1300347:I601 RS13525
gene id: 1300347:I601_RS13525
uniprot id: A0A1A9GNC3
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1300347:I601 RS03910
gene id: 1300347:I601_RS03910
uniprot id: A0A1A9GG76
names: Similarity
messages: Belongs to the isochorismate synthase family.

1300347:I601 RS08745
gene id: 1300347:I601_RS08745
uniprot id: A0A1A9GJG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

1300347:I601 RS08295
gene id: 1300347:I601_RS08295
uniprot id: A0A1A9GIH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1300347:I601 RS14300
gene id: 1300347:I601_RS14300
uniprot id: A0A1A9GML0
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1300347:I601 RS08400
gene id: 1300347:I601_RS08400
uniprot id: A0A1A9GIJ2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1300347:I601 RS09700
gene id: 1300347:I601_RS09700
uniprot id: A0A1A9GJ90
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300347:I601 RS04190
gene id: 1300347:I601_RS04190
uniprot id: A0A1A9GIG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1300347:I601 RS04890
gene id: 1300347:I601_RS04890
uniprot id: A0A1A9GIU5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300347:I601 RS12505
gene id: 1300347:I601_RS12505
uniprot id: A0A1A9GKY1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1300347:I601 RS01080
gene id: 1300347:I601_RS01080
uniprot id: A0A1A9GGR5
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1300347:I601 RS01175
gene id: 1300347:I601_RS01175
uniprot id: A0A1A9GEM6
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1300347:I601 RS16060
gene id: 1300347:I601_RS16060
uniprot id: A0A1A9GMX3
names: Similarity
messages: Belongs to the UPF0749 family.

1300347:I601 RS10880
gene id: 1300347:I601_RS10880
uniprot id: A0A1A9GLU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

1300347:I601 RS01325
gene id: 1300347:I601_RS01325
uniprot id: A0A1A9GEQ4
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1300347:I601 RS17720
gene id: 1300347:I601_RS17720
uniprot id: A0A1A9GR94
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1300347:I601 RS13245
gene id: 1300347:I601_RS13245
uniprot id: A0A1A9GL80
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1300347:I601 RS15900
gene id: 1300347:I601_RS15900
uniprot id: A0A1A9GMV6
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS14405
gene id: 1300347:I601_RS14405
uniprot id: A0A1A9GMN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1300347:I601 RS08560
gene id: 1300347:I601_RS08560
uniprot id: A0A1A9GKF9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1300347:I601 RS12090
gene id: 1300347:I601_RS12090
uniprot id: A0A1A9GKJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1300347:I601 RS09275
gene id: 1300347:I601_RS09275
uniprot id: A0A1A9GKY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1300347:I601 RS08840
gene id: 1300347:I601_RS08840
uniprot id: A0A1A9GLA4
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS08345
gene id: 1300347:I601_RS08345
uniprot id: A0A1A9GII2
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1300347:I601 RS12935
gene id: 1300347:I601_RS12935
uniprot id: A0A1A9GNL3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1300347:I601 RS01300
gene id: 1300347:I601_RS01300
uniprot id: A0A1A9GEG5
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1300347:I601 RS10265
gene id: 1300347:I601_RS10265
uniprot id: A0A1A9GLE7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1300347:I601 RS14820
gene id: 1300347:I601_RS14820
uniprot id: A0A1A9GM96
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1300347:I601 RS08440
gene id: 1300347:I601_RS08440
uniprot id: A0A1A9GJ88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1300347:I601 RS10565
gene id: 1300347:I601_RS10565
uniprot id: A0A1A9GJX4
names: Similarity
messages: Belongs to the intimin/invasin family.

1300347:I601 RS07255
gene id: 1300347:I601_RS07255
uniprot id: A0A1A9GJQ5
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

1300347:I601 RS14690
gene id: 1300347:I601_RS14690
uniprot id: A0A1A9GM68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1300347:I601 RS14355
gene id: 1300347:I601_RS14355
uniprot id: A0A1A9GMM0
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1300347:I601 RS17020
gene id: 1300347:I601_RS17020
uniprot id: A0A1A9GQH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1300347:I601 RS18665
gene id: 1300347:I601_RS18665
uniprot id: A0A1A9GRA1
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS10220
gene id: 1300347:I601_RS10220
uniprot id: A0A1A9GLZ2
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1300347:I601 RS13590
gene id: 1300347:I601_RS13590
uniprot id: A0A1A9GLL9
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1300347:I601 RS01240
gene id: 1300347:I601_RS01240
uniprot id: A0A1A9GEK7
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

1300347:I601 RS03935
gene id: 1300347:I601_RS03935
uniprot id: A0A1A9GFY5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1300347:I601 RS09160
gene id: 1300347:I601_RS09160
uniprot id: A0A1A9GKT1
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1300347:I601 RS16755
gene id: 1300347:I601_RS16755
uniprot id: A0A1A9GNA6
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
messages: Homodimer.
messages: In the C-terminal section; belongs to the MurCDEF family.

1300347:I601 RS17885
gene id: 1300347:I601_RS17885
uniprot id: A0A1A9GNZ9
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS08425
gene id: 1300347:I601_RS08425
uniprot id: A0A1A9GKL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1300347:I601 RS19150
gene id: 1300347:I601_RS19150
uniprot id: A0A1A9GPQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1300347:I601 RS04280
gene id: 1300347:I601_RS04280
uniprot id: A0A1A9GGA8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1300347:I601 RS09630
gene id: 1300347:I601_RS09630
uniprot id: A0A1A9GLA5
names: Similarity
messages: Belongs to the peptidase S1C family.

1300347:I601 RS04660
gene id: 1300347:I601_RS04660
uniprot id: A0A1A9GGM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1300347:I601 RS08125
gene id: 1300347:I601_RS08125
uniprot id: A0A1A9GK88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1300347:I601 RS19520
gene id: 1300347:I601_RS19520
uniprot id: A0A1A9GRX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1300347:I601 RS02330
gene id: 1300347:I601_RS02330
uniprot id: A0A1A9GFU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1300347:I601 RS13880
gene id: 1300347:I601_RS13880
uniprot id: A0A1A9GP25
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1300347:I601 RS18725
gene id: 1300347:I601_RS18725
uniprot id: A0A1A9GRD8
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS08155
gene id: 1300347:I601_RS08155
uniprot id: A0A1A9GID4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Heterodimer of an alpha and a beta chain.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300347:I601 RS17995
gene id: 1300347:I601_RS17995
uniprot id: A0A1A9GQV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1300347:I601 RS06165
gene id: 1300347:I601_RS06165
uniprot id: A0A1A9GHB7
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

1300347:I601 RS16090
gene id: 1300347:I601_RS16090
uniprot id: A0A1A9GMZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1300347:I601 RS05365
gene id: 1300347:I601_RS05365
uniprot id: A0A1A9GJ86
names: Similarity
messages: Belongs to the CFA/CMAS family.

1300347:I601 RS14615
gene id: 1300347:I601_RS14615
uniprot id: A0A1A9GP34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

1300347:I601 RS04315
gene id: 1300347:I601_RS04315
uniprot id: A0A1A9GGF2
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS18330
gene id: 1300347:I601_RS18330
uniprot id: A0A1A9GP77
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

1300347:I601 RS18410
gene id: 1300347:I601_RS18410
uniprot id: A0A1A9GP92
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1300347:I601 RS19500
gene id: 1300347:I601_RS19500
uniprot id: A0A1A9GPY2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300347:I601 RS11440
gene id: 1300347:I601_RS11440
uniprot id: A0A1A9GMB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1300347:I601 RS16235
gene id: 1300347:I601_RS16235
uniprot id: A0A1A9GN27
names: Similarity
messages: Belongs to the ComB family.

1300347:I601 RS15830
gene id: 1300347:I601_RS15830
uniprot id: A0A1A9GPL1
names: Similarity
messages: Belongs to the TPP enzyme family.

1300347:I601 RS05625
gene id: 1300347:I601_RS05625
uniprot id: A0A1A9GH00
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1300347:I601 RS04425
gene id: 1300347:I601_RS04425
uniprot id: A0A1A9GGB9
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1300347:I601 RS10120
gene id: 1300347:I601_RS10120
uniprot id: A0A1A9GLC0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

1300347:I601 RS19610
gene id: 1300347:I601_RS19610
uniprot id: A0A1A9GRQ3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1300347:I601 RS02120
gene id: 1300347:I601_RS02120
uniprot id: A0A1A9GF55
names: Similarity
messages: Belongs to the CdaR family.

1300347:I601 RS09245
gene id: 1300347:I601_RS09245
uniprot id: A0A1A9GJQ8
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1300347:I601 RS17140
gene id: 1300347:I601_RS17140
uniprot id: A0A1A9GNG2
names: Similarity
messages: Belongs to the cytochrome P450 family.

1300347:I601 RS03960
gene id: 1300347:I601_RS03960
uniprot id: A0A1A9GI12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1300347:I601 RS13165
gene id: 1300347:I601_RS13165
uniprot id: A0A1A9GNM8
names: Similarity
messages: Belongs to the peptidase C40 family.

1300347:I601 RS02820
gene id: 1300347:I601_RS02820
uniprot id: A0A1A9GFK2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1300347:I601 RS16180
gene id: 1300347:I601_RS16180
uniprot id: A0A1A9GPZ9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1300347:I601 RS13530
gene id: 1300347:I601_RS13530
uniprot id: A0A1A9GNI5
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1300347:I601 RS07465
gene id: 1300347:I601_RS07465
uniprot id: A0A1A9GK09
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

1300347:I601 RS01450
gene id: 1300347:I601_RS01450
uniprot id: A0A1A9GEJ5
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1300347:I601 RS05545
gene id: 1300347:I601_RS05545
uniprot id: A0A1A9GJ84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1300347:I601 RS13495
gene id: 1300347:I601_RS13495
uniprot id: A0A1A9GLD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1300347:I601 RS05890
gene id: 1300347:I601_RS05890
uniprot id: A0A1A9GIW4
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

1300347:I601 RS03065
gene id: 1300347:I601_RS03065
uniprot id: A0A1A9GHI8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1300347:I601 RS12515
gene id: 1300347:I601_RS12515
uniprot id: A0A1A9GMP7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1300347:I601 RS18535
gene id: 1300347:I601_RS18535
uniprot id: A0A1A9GPB3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1300347:I601 RS11640
gene id: 1300347:I601_RS11640
uniprot id: A0A1A9GKF5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1300347:I601 RS12285
gene id: 1300347:I601_RS12285
uniprot id: A0A1A9GN75
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1300347:I601 RS15050
gene id: 1300347:I601_RS15050
uniprot id: A0A1A9GP68
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1300347:I601 RS09090
gene id: 1300347:I601_RS09090
uniprot id: A0A1A9GJN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1300347:I601 RS01850
gene id: 1300347:I601_RS01850
uniprot id: A0A1A9GGM3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1300347:I601 RS07060
gene id: 1300347:I601_RS07060
uniprot id: A0A1A9GJS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1300347:I601 RS05040
gene id: 1300347:I601_RS05040
uniprot id: A0A1A9GIF0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1300347:I601 RS12435
gene id: 1300347:I601_RS12435
uniprot id: A0A1A9GKY6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1300347:I601 RS00125
gene id: 1300347:I601_RS00125
uniprot id: A0A1A9GFQ8
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS01350
gene id: 1300347:I601_RS01350
uniprot id: A0A1A9GEH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1300347:I601 RS04485
gene id: 1300347:I601_RS04485
uniprot id: A0A1A9GG93
names: Similarity
messages: Belongs to the peptidase M28 family. M28A subfamily.

1300347:I601 RS18965
gene id: 1300347:I601_RS18965
uniprot id: A0A1A9GS20
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300347:I601 RS13775
gene id: 1300347:I601_RS13775
uniprot id: A0A1A9GNG1
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1300347:I601 RS16810
gene id: 1300347:I601_RS16810
uniprot id: A0A1A9GQ63
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1300347:I601 RS02810
gene id: 1300347:I601_RS02810
uniprot id: A0A1A9GHA3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1300347:I601 RS04080
gene id: 1300347:I601_RS04080
uniprot id: A0A1A9GG14
names: Similarity
messages: Belongs to the histone deacetylase family.

1300347:I601 RS16990
gene id: 1300347:I601_RS16990
uniprot id: A0A1A9GND3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1300347:I601 RS09660
gene id: 1300347:I601_RS09660
uniprot id: A0A1A9GJC1
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1300347:I601 RS16950
gene id: 1300347:I601_RS16950
uniprot id: A0A1A9GNE4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1300347:I601 RS03715
gene id: 1300347:I601_RS03715
uniprot id: A0A1A9GG01
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1300347:I601 RS01370
gene id: 1300347:I601_RS01370
uniprot id: A0A1A9GGI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

1300347:I601 RS15145
gene id: 1300347:I601_RS15145
uniprot id: A0A1A9GMG1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1300347:I601 RS16470
gene id: 1300347:I601_RS16470
uniprot id: A0A1A9GQ62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1300347:I601 RS13575
gene id: 1300347:I601_RS13575
uniprot id: A0A1A9GNW8
names: Subcellular Location Annotation
messages: Cytoplasm

1300347:I601 RS19185
gene id: 1300347:I601_RS19185
uniprot id: A0A1A9GS18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

1300347:I601 RS18220
gene id: 1300347:I601_RS18220
uniprot id: A0A1A9GP36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1300347:I601 RS17805
gene id: 1300347:I601_RS17805
uniprot id: A0A1A9GQT0
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

1300347:I601 RS15000
gene id: 1300347:I601_RS15000
uniprot id: A0A1A9GP58
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1300347:I601 RS18495
gene id: 1300347:I601_RS18495
uniprot id: A0A1A9GPC2
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS06125
gene id: 1300347:I601_RS06125
uniprot id: A0A1A9GHB2
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS03050
gene id: 1300347:I601_RS03050
uniprot id: A0A1A9GHB6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1300347:I601 RS10105
gene id: 1300347:I601_RS10105
uniprot id: A0A1A9GJG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1300347:I601 RS08365
gene id: 1300347:I601_RS08365
uniprot id: A0A1A9GKX4
names: Similarity
messages: Belongs to the Nth/MutY family.

1300347:I601 RS07005
gene id: 1300347:I601_RS07005
uniprot id: A0A1A9GJL0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1300347:I601 RS06990
gene id: 1300347:I601_RS06990
uniprot id: A0A1A9GHP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1300347:I601 RS09425
gene id: 1300347:I601_RS09425
uniprot id: A0A1A9GL69
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1300347:I601 RS12900
gene id: 1300347:I601_RS12900
uniprot id: A0A1A9GL67
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1300347:I601 RS09610
gene id: 1300347:I601_RS09610
uniprot id: A0A1A9GJB0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1300347:I601 RS09680
gene id: 1300347:I601_RS09680
uniprot id: A0A1A9GLB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

1300347:I601 RS09350
gene id: 1300347:I601_RS09350
uniprot id: A0A1A9GJ95
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300347:I601 RS06790
gene id: 1300347:I601_RS06790
uniprot id: A0A1A9GJZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1300347:I601 RS03675
gene id: 1300347:I601_RS03675
uniprot id: A0A1A9GI61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1300347:I601 RS04105
gene id: 1300347:I601_RS04105
uniprot id: A0A1A9GGB1
names: Cofactor
messages: Binds 1 FAD per subunit.

1300347:I601 RS06405
gene id: 1300347:I601_RS06405
uniprot id: A0A1A9GHL5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300347:I601 RS03835
gene id: 1300347:I601_RS03835
uniprot id: A0A1A9GFX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1300347:I601 RS13805
gene id: 1300347:I601_RS13805
uniprot id: A0A1A9GMA4
names: Similarity
messages: Belongs to the glutamine synthetase family.

1300347:I601 RS05835
gene id: 1300347:I601_RS05835
uniprot id: A0A1A9GH21
names: Similarity
messages: Belongs to the cytochrome P450 family.

1300347:I601 RS00730
gene id: 1300347:I601_RS00730
uniprot id: A0A1A9GGJ4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1300347:I601 RS18540
gene id: 1300347:I601_RS18540
uniprot id: A0A1A9GRQ8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1300347:I601 RS03940
gene id: 1300347:I601_RS03940
uniprot id: A0A1A9GHU5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

1300347:I601 RS04160
gene id: 1300347:I601_RS04160
uniprot id: A0A1A9GIL0
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS05140
gene id: 1300347:I601_RS05140
uniprot id: A0A1A9GIG9
names: Caution
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300347:I601 RS16940
gene id: 1300347:I601_RS16940
uniprot id: A0A1A9GNC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Membrane

1300347:I601 RS13090
gene id: 1300347:I601_RS13090
uniprot id: A0A1A9GLU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

1300347:I601 RS05875
gene id: 1300347:I601_RS05875
uniprot id: A0A1A9GH55
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1300347:I601 RS16710
gene id: 1300347:I601_RS16710
uniprot id: A0A1A9GQ41
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1300347:I601 RS13040
gene id: 1300347:I601_RS13040
uniprot id: A0A1A9GLT4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1300347:I601 RS02195
gene id: 1300347:I601_RS02195
uniprot id: A0A1A9GEX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1300347:I601 RS16705
gene id: 1300347:I601_RS16705
uniprot id: A0A1A9GN97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1300347:I601 RS12275
gene id: 1300347:I601_RS12275
uniprot id: A0A1A9GMS4
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1300347:I601 RS10810
gene id: 1300347:I601_RS10810
uniprot id: A0A1A9GK15
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

1300347:I601 RS14955
gene id: 1300347:I601_RS14955
uniprot id: A0A1A9GPM6
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1300347:I601 RS16305
gene id: 1300347:I601_RS16305
uniprot id: A0A1A9GN26
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

1300347:I601 RS05880
gene id: 1300347:I601_RS05880
uniprot id: A0A1A9GH57
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1300347:I601 RS05240
gene id: 1300347:I601_RS05240
uniprot id: A0A1A9GIJ0
names: Function
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: May catalyze the transamination reaction in phenylalanine biosynthesis.

1300347:I601 RS07275
gene id: 1300347:I601_RS07275
uniprot id: A0A1A9GIJ5
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300347:I601 RS16035
gene id: 1300347:I601_RS16035
uniprot id: A0A1A9GPW9
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS01585
gene id: 1300347:I601_RS01585
uniprot id: A0A1A9GER8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1300347:I601 RS02280
gene id: 1300347:I601_RS02280
uniprot id: A0A1A9GFT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1300347:I601 RS06710
gene id: 1300347:I601_RS06710
uniprot id: A0A1A9GHS3
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS03890
gene id: 1300347:I601_RS03890
uniprot id: A0A1A9GHT4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1300347:I601 RS16510
gene id: 1300347:I601_RS16510
uniprot id: A0A1A9GQJ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

1300347:I601 RS04455
gene id: 1300347:I601_RS04455
uniprot id: A0A1A9GI98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1300347:I601 RS00465
gene id: 1300347:I601_RS00465
uniprot id: A0A1A9GFX9
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.

1300347:I601 RS12605
gene id: 1300347:I601_RS12605
uniprot id: A0A1A9GKZ3
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1300347:I601 RS01455
gene id: 1300347:I601_RS01455
uniprot id: A0A1A9GGD6
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS01400
gene id: 1300347:I601_RS01400
uniprot id: A0A1A9GEI5
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS19625
gene id: 1300347:I601_RS19625
uniprot id: A0A1A9GRT8
names: Similarity
messages: Belongs to the TPP enzyme family.

1300347:I601 RS02375
gene id: 1300347:I601_RS02375
uniprot id: A0A1A9GHI5
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS11805
gene id: 1300347:I601_RS11805
uniprot id: A0A1A9GMA2
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1300347:I601 RS17135
gene id: 1300347:I601_RS17135
uniprot id: A0A1A9GP51
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1300347:I601 RS04320
gene id: 1300347:I601_RS04320
uniprot id: A0A1A9GIN5
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS07170
gene id: 1300347:I601_RS07170
uniprot id: A0A1A9GKA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

1300347:I601 RS10065
gene id: 1300347:I601_RS10065
uniprot id: A0A1A9GJK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1300347:I601 RS13605
gene id: 1300347:I601_RS13605
uniprot id: A0A1A9GLG2
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1300347:I601 RS03645
gene id: 1300347:I601_RS03645
uniprot id: A0A1A9GIB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1300347:I601 RS17190
gene id: 1300347:I601_RS17190
uniprot id: A0A1A9GNH2
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

1300347:I601 RS03820
gene id: 1300347:I601_RS03820
uniprot id: A0A1A9GGN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1300347:I601 RS11445
gene id: 1300347:I601_RS11445
uniprot id: A0A1A9GKE8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1300347:I601 RS03975
gene id: 1300347:I601_RS03975
uniprot id: A0A1A9GG30
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS11840
gene id: 1300347:I601_RS11840
uniprot id: A0A1A9GKE7
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS16055
gene id: 1300347:I601_RS16055
uniprot id: A0A1A9GMV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

1300347:I601 RS12880
gene id: 1300347:I601_RS12880
uniprot id: A0A1A9GL72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1300347:I601 RS02135
gene id: 1300347:I601_RS02135
uniprot id: A0A1A9GF16
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS17060
gene id: 1300347:I601_RS17060
uniprot id: A0A1A9GQV7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1300347:I601 RS11555
gene id: 1300347:I601_RS11555
uniprot id: A0A1A9GKG7
names: Similarity
messages: Belongs to the pirin family.

1300347:I601 RS12495
gene id: 1300347:I601_RS12495
uniprot id: A0A1A9GLH8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1300347:I601 RS14720
gene id: 1300347:I601_RS14720
uniprot id: A0A1A9GM75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1300347:I601 RS03580
gene id: 1300347:I601_RS03580
uniprot id: A0A1A9GHQ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1300347:I601 RS09875
gene id: 1300347:I601_RS09875
uniprot id: A0A1A9GLS3
names: Similarity
messages: Belongs to the universal stress protein A family.

1300347:I601 RS06230
gene id: 1300347:I601_RS06230
uniprot id: A0A1A9GJ33
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1300347:I601 RS02255
gene id: 1300347:I601_RS02255
uniprot id: A0A1A9GHA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1300347:I601 RS14255
gene id: 1300347:I601_RS14255
uniprot id: A0A1A9GLU0
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1300347:I601 RS09575
gene id: 1300347:I601_RS09575
uniprot id: A0A1A9GL37
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS01220
gene id: 1300347:I601_RS01220
uniprot id: A0A1A9GGF8
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

1300347:I601 RS18030
gene id: 1300347:I601_RS18030
uniprot id: A0A1A9GNZ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1300347:I601 RS07565
gene id: 1300347:I601_RS07565
uniprot id: A0A1A9GKF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1300347:I601 RS14425
gene id: 1300347:I601_RS14425
uniprot id: A0A1A9GNT8
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase involved in purine salvage.

1300347:I601 RS05260
gene id: 1300347:I601_RS05260
uniprot id: A0A1A9GGZ0
names: Similarity
messages: Belongs to the fructosamine kinase family.

1300347:I601 RS15320
gene id: 1300347:I601_RS15320
uniprot id: A0A1A9GPU8
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

1300347:I601 RS20270
gene id: 1300347:I601_RS20270
uniprot id: A0A1A9GSC4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1300347:I601 RS02075
gene id: 1300347:I601_RS02075
uniprot id: A0A1A9GHC4
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS02420
gene id: 1300347:I601_RS02420
uniprot id: A0A1A9GFA9
names: Similarity
messages: Belongs to the peptidase S8 family.

1300347:I601 RS10455
gene id: 1300347:I601_RS10455
uniprot id: A0A1A9GKD8
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS01505
gene id: 1300347:I601_RS01505
uniprot id: A0A1A9GGV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1300347:I601 RS10015
gene id: 1300347:I601_RS10015
uniprot id: A0A1A9GJJ2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

1300347:I601 RS19770
gene id: 1300347:I601_RS19770
uniprot id: A0A1A9GSH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

1300347:I601 RS13990
gene id: 1300347:I601_RS13990
uniprot id: A0A1A9GNR9
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

1300347:I601 RS08435
gene id: 1300347:I601_RS08435
uniprot id: A0A1A9GL09
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1300347:I601 RS20030
gene id: 1300347:I601_RS20030
uniprot id: A0A1A9GS15
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1300347:I601 RS19330
gene id: 1300347:I601_RS19330
uniprot id: A0A1A9GPS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

1300347:I601 RS12600
gene id: 1300347:I601_RS12600
uniprot id: A0A1A9GL03
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

1300347:I601 RS14995
gene id: 1300347:I601_RS14995
uniprot id: A0A1A9GMD1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1300347:I601 RS01680
gene id: 1300347:I601_RS01680
uniprot id: A0A1A9GET7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1300347:I601 RS11715
gene id: 1300347:I601_RS11715
uniprot id: A0A1A9GKJ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

1300347:I601 RS16730
gene id: 1300347:I601_RS16730
uniprot id: A0A1A9GNC1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1300347:I601 RS04770
gene id: 1300347:I601_RS04770
uniprot id: A0A1A9GGI7
names: Similarity
messages: Belongs to the peptidase M1 family.

1300347:I601 RS14270
gene id: 1300347:I601_RS14270
uniprot id: A0A1A9GNQ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1300347:I601 RS18010
gene id: 1300347:I601_RS18010
uniprot id: A0A1A9GR09
names: Similarity
messages: Belongs to the universal stress protein A family.

1300347:I601 RS14850
gene id: 1300347:I601_RS14850
uniprot id: A0A1A9GP24
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1300347:I601 RS03175
gene id: 1300347:I601_RS03175
uniprot id: A0A1A9GHK9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1300347:I601 RS07800
gene id: 1300347:I601_RS07800
uniprot id: A0A1A9GIA3
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1300347:I601 RS14345
gene id: 1300347:I601_RS14345
uniprot id: A0A1A9GM12
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

1300347:I601 RS15780
gene id: 1300347:I601_RS15780
uniprot id: A0A1A9GMS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1300347:I601 RS19475
gene id: 1300347:I601_RS19475
uniprot id: A0A1A9GRR8
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1300347:I601 RS20140
gene id: 1300347:I601_RS20140
uniprot id: A0A1A9GQV0
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS20055
gene id: 1300347:I601_RS20055
uniprot id: A0A1A9GQ87
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS19000
gene id: 1300347:I601_RS19000
uniprot id: A0A1A9GPM2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1300347:I601 RS14685
gene id: 1300347:I601_RS14685
uniprot id: A0A1A9GM16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

1300347:I601 RS17070
gene id: 1300347:I601_RS17070
uniprot id: A0A1A9GQI1
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

1300347:I601 RS08195
gene id: 1300347:I601_RS08195
uniprot id: A0A1A9GIE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1300347:I601 RS08245
gene id: 1300347:I601_RS08245
uniprot id: A0A1A9GIF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1300347:I601 RS14935
gene id: 1300347:I601_RS14935
uniprot id: A0A1A9GM69
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300347:I601 RS04835
gene id: 1300347:I601_RS04835
uniprot id: A0A1A9GIA9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1300347:I601 RS09740
gene id: 1300347:I601_RS09740
uniprot id: A0A1A9GLS6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1300347:I601 RS09765
gene id: 1300347:I601_RS09765
uniprot id: A0A1A9GL51
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1300347:I601 RS02690
gene id: 1300347:I601_RS02690
uniprot id: A0A1A9GFE6
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1300347:I601 RS07560
gene id: 1300347:I601_RS07560
uniprot id: A0A1A9GJV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1300347:I601 RS19400
gene id: 1300347:I601_RS19400
uniprot id: A0A1A9GPW2
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1300347:I601 RS05725
gene id: 1300347:I601_RS05725
uniprot id: A0A1A9GH20
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS09330
gene id: 1300347:I601_RS09330
uniprot id: A0A1A9GJ89
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1300347:I601 RS10295
gene id: 1300347:I601_RS10295
uniprot id: A0A1A9GKA9
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1300347:I601 RS05320
gene id: 1300347:I601_RS05320
uniprot id: A0A1A9GHH1
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1300347:I601 RS02685
gene id: 1300347:I601_RS02685
uniprot id: A0A1A9GFC6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1300347:I601 RS18805
gene id: 1300347:I601_RS18805
uniprot id: A0A1A9GPH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1300347:I601 RS19435
gene id: 1300347:I601_RS19435
uniprot id: A0A1A9GS66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1300347:I601 RS06120
gene id: 1300347:I601_RS06120
uniprot id: A0A1A9GHA5
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1300347:I601 RS15775
gene id: 1300347:I601_RS15775
uniprot id: A0A1A9GMR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1300347:I601 RS07280
gene id: 1300347:I601_RS07280
uniprot id: A0A1A9GHX0
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS19955
gene id: 1300347:I601_RS19955
uniprot id: A0A1A9GQ65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane

1300347:I601 RS16445
gene id: 1300347:I601_RS16445
uniprot id: A0A1A9GN52
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1300347:I601 RS08965
gene id: 1300347:I601_RS08965
uniprot id: A0A1A9GKP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

1300347:I601 RS02015
gene id: 1300347:I601_RS02015
uniprot id: A0A1A9GGX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1300347:I601 RS03855
gene id: 1300347:I601_RS03855
uniprot id: A0A1A9GHZ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1300347:I601 RS06725
gene id: 1300347:I601_RS06725
uniprot id: A0A1A9GHL7
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1300347:I601 RS18825
gene id: 1300347:I601_RS18825
uniprot id: A0A1A9GRE7
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1300347:I601 RS03895
gene id: 1300347:I601_RS03895
uniprot id: A0A1A9GI96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1300347:I601 RS14700
gene id: 1300347:I601_RS14700
uniprot id: A0A1A9GNZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1300347:I601 RS13025
gene id: 1300347:I601_RS13025
uniprot id: A0A1A9GN80
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1300347:I601 RS13845
gene id: 1300347:I601_RS13845
uniprot id: A0A1A9GLR7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300347:I601 RS11615
gene id: 1300347:I601_RS11615
uniprot id: A0A1A9GKH7
names: Similarity
messages: Belongs to the peptidase M24B family.

1300347:I601 RS01780
gene id: 1300347:I601_RS01780
uniprot id: A0A1A9GEV5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1300347:I601 RS18820
gene id: 1300347:I601_RS18820
uniprot id: A0A1A9GRG1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1300347:I601 RS18065
gene id: 1300347:I601_RS18065
uniprot id: A0A1A9GP28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1300347:I601 RS04685
gene id: 1300347:I601_RS04685
uniprot id: A0A1A9GGD4
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1300347:I601 RS11860
gene id: 1300347:I601_RS11860
uniprot id: A0A1A9GMV9
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS12985
gene id: 1300347:I601_RS12985
uniprot id: A0A1A9GNM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1300347:I601 RS07585
gene id: 1300347:I601_RS07585
uniprot id: A0A1A9GKI3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300347:I601 RS16820
gene id: 1300347:I601_RS16820
uniprot id: A0A1A9GQ83
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS02430
gene id: 1300347:I601_RS02430
uniprot id: A0A1A9GFW0
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS17880
gene id: 1300347:I601_RS17880
uniprot id: A0A1A9GNW0
names: Similarity
messages: Belongs to the LppX/LprAFG lipoprotein family.

1300347:I601 RS20395
gene id: 1300347:I601_RS20395
uniprot id: A0A1A9GQG1
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS18415
gene id: 1300347:I601_RS18415
uniprot id: A0A1A9GRM8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1300347:I601 RS02300
gene id: 1300347:I601_RS02300
uniprot id: A0A1A9GGW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1300347:I601 RS17285
gene id: 1300347:I601_RS17285
uniprot id: A0A1A9GP85
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1300347:I601 RS06855
gene id: 1300347:I601_RS06855
uniprot id: A0A1A9GHV1
names: Function
names: Similarity
messages: Belongs to the LarC family.
messages: Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes.

1300347:I601 RS03925
gene id: 1300347:I601_RS03925
uniprot id: A0A1A9GG21
names: Similarity
messages: Belongs to the cytochrome P450 family.

1300347:I601 RS02235
gene id: 1300347:I601_RS02235
uniprot id: A0A1A9GF38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1300347:I601 RS10905
gene id: 1300347:I601_RS10905
uniprot id: A0A1A9GJX0
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

1300347:I601 RS01285
gene id: 1300347:I601_RS01285
uniprot id: A0A1A9GF69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1300347:I601 RS05530
gene id: 1300347:I601_RS05530
uniprot id: A0A1A9GGZ8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1300347:I601 RS00215
gene id: 1300347:I601_RS00215
uniprot id: A0A1A9GG51
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300347:I601 RS02200
gene id: 1300347:I601_RS02200
uniprot id: A0A1A9GGU5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1300347:I601 RS15225
gene id: 1300347:I601_RS15225
uniprot id: A0A1A9GP97
names: Similarity
messages: Belongs to the TlyA family.

1300347:I601 RS18670
gene id: 1300347:I601_RS18670
uniprot id: A0A1A9GRV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1300347:I601 RS14895
gene id: 1300347:I601_RS14895
uniprot id: A0A1A9GM97
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1300347:I601 RS15175
gene id: 1300347:I601_RS15175
uniprot id: A0A1A9GPV7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1300347:I601 RS16300
gene id: 1300347:I601_RS16300
uniprot id: A0A1A9GN25
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS14200
gene id: 1300347:I601_RS14200
uniprot id: A0A1A9GMI9
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS07700
gene id: 1300347:I601_RS07700
uniprot id: A0A1A9GI79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1300347:I601 RS10390
gene id: 1300347:I601_RS10390
uniprot id: A0A1A9GLQ2
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

1300347:I601 RS02735
gene id: 1300347:I601_RS02735
uniprot id: A0A1A9GFE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1300347:I601 RS00640
gene id: 1300347:I601_RS00640
uniprot id: A0A1A9GE81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1300347:I601 RS09430
gene id: 1300347:I601_RS09430
uniprot id: A0A1A9GJA8
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1300347:I601 RS19420
gene id: 1300347:I601_RS19420
uniprot id: A0A1A9GRU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1300347:I601 RS03830
gene id: 1300347:I601_RS03830
uniprot id: A0A1A9GG26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1300347:I601 RS14240
gene id: 1300347:I601_RS14240
uniprot id: A0A1A9GLZ1
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1300347:I601 RS14010
gene id: 1300347:I601_RS14010
uniprot id: A0A1A9GLP5
names: Similarity
messages: Belongs to the universal stress protein A family.

1300347:I601 RS02180
gene id: 1300347:I601_RS02180
uniprot id: A0A1A9GFR2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1300347:I601 RS19800
gene id: 1300347:I601_RS19800
uniprot id: A0A1A9GPX6
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

1300347:I601 RS11155
gene id: 1300347:I601_RS11155
uniprot id: A0A1A9GKS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1300347:I601 RS14295
gene id: 1300347:I601_RS14295
uniprot id: A0A1A9GPD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1300347:I601 RS04305
gene id: 1300347:I601_RS04305
uniprot id: A0A1A9GI35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1300347:I601 RS02215
gene id: 1300347:I601_RS02215
uniprot id: A0A1A9GH18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1300347:I601 RS11490
gene id: 1300347:I601_RS11490
uniprot id: A0A1A9GM59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

1300347:I601 RS01965
gene id: 1300347:I601_RS01965
uniprot id: A0A1A9GGW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1300347:I601 RS12145
gene id: 1300347:I601_RS12145
uniprot id: A0A1A9GKR3
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

1300347:I601 RS12490
gene id: 1300347:I601_RS12490
uniprot id: A0A1A9GNC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

1300347:I601 RS08935
gene id: 1300347:I601_RS08935
uniprot id: A0A1A9GJ21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1300347:I601 RS14675
gene id: 1300347:I601_RS14675
uniprot id: A0A1A9GPK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1300347:I601 RS01115
gene id: 1300347:I601_RS01115
uniprot id: A0A1A9GGB6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1300347:I601 RS00170
gene id: 1300347:I601_RS00170
uniprot id: A0A1A9GFR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm

1300347:I601 RS10005
gene id: 1300347:I601_RS10005
uniprot id: A0A1A9GJE9
names: Similarity
messages: Belongs to the thioredoxin family.

1300347:I601 RS17790
gene id: 1300347:I601_RS17790
uniprot id: A0A1A9GNW2
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1300347:I601 RS17830
gene id: 1300347:I601_RS17830
uniprot id: A0A1A9GNU9
names: Similarity
messages: Belongs to the thymidine kinase family.

1300347:I601 RS01835
gene id: 1300347:I601_RS01835
uniprot id: A0A1A9GEW5
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.

1300347:I601 RS06815
gene id: 1300347:I601_RS06815
uniprot id: A0A1A9GIB1
names: Similarity
messages: Belongs to the FPG family.

1300347:I601 RS05285
gene id: 1300347:I601_RS05285
uniprot id: A0A1A9GGQ2
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300347:I601 RS15790
gene id: 1300347:I601_RS15790
uniprot id: A0A1A9GQ35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1300347:I601 RS15545
gene id: 1300347:I601_RS15545
uniprot id: A0A1A9GPF3
names: Similarity
messages: Belongs to the GSP E family.

1300347:I601 RS13945
gene id: 1300347:I601_RS13945
uniprot id: A0A1A9GLT5
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

1300347:I601 RS16125
gene id: 1300347:I601_RS16125
uniprot id: A0A1A9GQA7
names: Similarity
messages: Belongs to the Fur family.

1300347:I601 RS18760
gene id: 1300347:I601_RS18760
uniprot id: A0A1A9GPG5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1300347:I601 RS05770
gene id: 1300347:I601_RS05770
uniprot id: A0A1A9GHQ2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1300347:I601 RS12810
gene id: 1300347:I601_RS12810
uniprot id: A0A1A9GMW5
names: Similarity
messages: Belongs to the AAA ATPase family.

1300347:I601 RS16400
gene id: 1300347:I601_RS16400
uniprot id: A0A1A9GN45
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

1300347:I601 RS13700
gene id: 1300347:I601_RS13700
uniprot id: A0A1A9GM84
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1300347:I601 RS08715
gene id: 1300347:I601_RS08715
uniprot id: A0A1A9GIR8
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1300347:I601 RS00520
gene id: 1300347:I601_RS00520
uniprot id: A0A1A9GG16
names: Similarity
messages: Belongs to the asparagine synthetase family.

1300347:I601 RS20195
gene id: 1300347:I601_RS20195
uniprot id: A0A1A9GQW0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1300347:I601 RS12050
gene id: 1300347:I601_RS12050
uniprot id: A0A1A9GKN0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300347:I601 RS17770
gene id: 1300347:I601_RS17770
uniprot id: A0A1A9GRA4
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1300347:I601 RS05205
gene id: 1300347:I601_RS05205
uniprot id: A0A1A9GIP0
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1300347:I601 RS14890
gene id: 1300347:I601_RS14890
uniprot id: A0A1A9GMA5
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1300347:I601 RS08255
gene id: 1300347:I601_RS08255
uniprot id: A0A1A9GIF8
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1300347:I601 RS04255
gene id: 1300347:I601_RS04255
uniprot id: A0A1A9GIM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1300347:I601 RS18595
gene id: 1300347:I601_RS18595
uniprot id: A0A1A9GQ12
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1300347:I601 RS13560
gene id: 1300347:I601_RS13560
uniprot id: A0A1A9GLK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1300347:I601 RS13600
gene id: 1300347:I601_RS13600
uniprot id: A0A1A9GM64
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1300347:I601 RS06600
gene id: 1300347:I601_RS06600
uniprot id: A0A1A9GJC2
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS07715
gene id: 1300347:I601_RS07715
uniprot id: A0A1A9GKI6
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1300347:I601 RS01710
gene id: 1300347:I601_RS01710
uniprot id: A0A1A9GGQ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1300347:I601 RS17065
gene id: 1300347:I601_RS17065
uniprot id: A0A1A9GQD2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1300347:I601 RS10230
gene id: 1300347:I601_RS10230
uniprot id: A0A1A9GLM5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1300347:I601 RS12815
gene id: 1300347:I601_RS12815
uniprot id: A0A1A9GNF1
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300347:I601 RS17800
gene id: 1300347:I601_RS17800
uniprot id: A0A1A9GR98
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS03585
gene id: 1300347:I601_RS03585
uniprot id: A0A1A9GHU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1300347:I601 RS06845
gene id: 1300347:I601_RS06845
uniprot id: A0A1A9GJH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

1300347:I601 RS09355
gene id: 1300347:I601_RS09355
uniprot id: A0A1A9GJ60
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1300347:I601 RS04215
gene id: 1300347:I601_RS04215
uniprot id: A0A1A9GG79
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1300347:I601 RS11575
gene id: 1300347:I601_RS11575
uniprot id: A0A1A9GK96
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

1300347:I601 RS06195
gene id: 1300347:I601_RS06195
uniprot id: A0A1A9GJ98
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

1300347:I601 RS09000
gene id: 1300347:I601_RS09000
uniprot id: A0A1A9GIW5
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1300347:I601 RS15155
gene id: 1300347:I601_RS15155
uniprot id: A0A1A9GPR8
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1300347:I601 RS02360
gene id: 1300347:I601_RS02360
uniprot id: A0A1A9GH17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1300347:I601 RS20170
gene id: 1300347:I601_RS20170
uniprot id: A0A1A9GSB4
names: Similarity
messages: Belongs to the YjdM family.

1300347:I601 RS14075
gene id: 1300347:I601_RS14075
uniprot id: A0A1A9GP60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Membrane

1300347:I601 RS07835
gene id: 1300347:I601_RS07835
uniprot id: A0A1A9GKN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1300347:I601 RS14800
gene id: 1300347:I601_RS14800
uniprot id: A0A1A9GP14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1300347:I601 RS05565
gene id: 1300347:I601_RS05565
uniprot id: A0A1A9GJB7
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1300347:I601 RS04150
gene id: 1300347:I601_RS04150
uniprot id: A0A1A9GI50
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1300347:I601 RS11880
gene id: 1300347:I601_RS11880
uniprot id: A0A1A9GMZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1300347:I601 RS00530
gene id: 1300347:I601_RS00530
uniprot id: A0A1A9GGF5
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1300347:I601 RS00555
gene id: 1300347:I601_RS00555
uniprot id: A0A1A9GFV2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1300347:I601 RS10655
gene id: 1300347:I601_RS10655
uniprot id: A0A1A9GKH2
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1300347:I601 RS04555
gene id: 1300347:I601_RS04555
uniprot id: A0A1A9GIB5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1300347:I601 RS17740
gene id: 1300347:I601_RS17740
uniprot id: A0A1A9GNV2
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS04020
gene id: 1300347:I601_RS04020
uniprot id: A0A1A9GGS7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1300347:I601 RS08410
gene id: 1300347:I601_RS08410
uniprot id: A0A1A9GII7
names: Subcellular Location Annotation
messages: Cytoplasm

1300347:I601 RS14985
gene id: 1300347:I601_RS14985
uniprot id: A0A1A9GM81
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1300347:I601 RS01340
gene id: 1300347:I601_RS01340
uniprot id: A0A1A9GEM5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1300347:I601 RS02590
gene id: 1300347:I601_RS02590
uniprot id: A0A1A9GFC7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

1300347:I601 RS14805
gene id: 1300347:I601_RS14805
uniprot id: A0A1A9GPJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1300347:I601 RS16465
gene id: 1300347:I601_RS16465
uniprot id: A0A1A9GQ03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1300347:I601 RS19895
gene id: 1300347:I601_RS19895
uniprot id: A0A1A9GQP4
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS12170
gene id: 1300347:I601_RS12170
uniprot id: A0A1A9GKT5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1300347:I601 RS06480
gene id: 1300347:I601_RS06480
uniprot id: A0A1A9GHI0
names: Similarity
messages: Belongs to the CdaR family.

1300347:I601 RS18005
gene id: 1300347:I601_RS18005
uniprot id: A0A1A9GQW8
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1300347:I601 RS14610
gene id: 1300347:I601_RS14610
uniprot id: A0A1A9GNX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1300347:I601 RS12400
gene id: 1300347:I601_RS12400
uniprot id: A0A1A9GKQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1300347:I601 RS04775
gene id: 1300347:I601_RS04775
uniprot id: A0A1A9GGJ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

1300347:I601 RS06700
gene id: 1300347:I601_RS06700
uniprot id: A0A1A9GJE6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300347:I601 RS08105
gene id: 1300347:I601_RS08105
uniprot id: A0A1A9GIG5
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1300347:I601 RS00615
gene id: 1300347:I601_RS00615
uniprot id: A0A1A9GG10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1300347:I601 RS04185
gene id: 1300347:I601_RS04185
uniprot id: A0A1A9GHZ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300347:I601 RS07080
gene id: 1300347:I601_RS07080
uniprot id: A0A1A9GHT1
names: Similarity
messages: Belongs to the peptidase S58 family.

1300347:I601 RS02290
gene id: 1300347:I601_RS02290
uniprot id: A0A1A9GF68
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1300347:I601 RS07570
gene id: 1300347:I601_RS07570
uniprot id: A0A1A9GJX3
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1300347:I601 RS11430
gene id: 1300347:I601_RS11430
uniprot id: A0A1A9GMM6
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS16380
gene id: 1300347:I601_RS16380
uniprot id: A0A1A9GQK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1300347:I601 RS14410
gene id: 1300347:I601_RS14410
uniprot id: A0A1A9GLX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1300347:I601 RS15835
gene id: 1300347:I601_RS15835
uniprot id: A0A1A9GQ47
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS03000
gene id: 1300347:I601_RS03000
uniprot id: A0A1A9GHA8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1300347:I601 RS00435
gene id: 1300347:I601_RS00435
uniprot id: A0A1A9GEQ9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1300347:I601 RS03880
gene id: 1300347:I601_RS03880
uniprot id: A0A1A9GG35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1300347:I601 RS06945
gene id: 1300347:I601_RS06945
uniprot id: A0A1A9GJJ8
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1300347:I601 RS17730
gene id: 1300347:I601_RS17730
uniprot id: A0A1A9GNT2
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

1300347:I601 RS16190
gene id: 1300347:I601_RS16190
uniprot id: A0A1A9GQF7
names: Similarity
messages: Belongs to the DSD1 family.

1300347:I601 RS08665
gene id: 1300347:I601_RS08665
uniprot id: A0A1A9GIX7
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1300347:I601 RS01170
gene id: 1300347:I601_RS01170
uniprot id: A0A1A9GGE6
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

1300347:I601 RS07970
gene id: 1300347:I601_RS07970
uniprot id: A0A1A9GKN8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1300347:I601 RS05895
gene id: 1300347:I601_RS05895
uniprot id: A0A1A9GJF2
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS17415
gene id: 1300347:I601_RS17415
uniprot id: A0A1A9GQK2
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

1300347:I601 RS05360
gene id: 1300347:I601_RS05360
uniprot id: A0A1A9GH14
names: Similarity
messages: Belongs to the CFA/CMAS family.

1300347:I601 RS06090
gene id: 1300347:I601_RS06090
uniprot id: A0A1A9GJJ4
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

1300347:I601 RS00680
gene id: 1300347:I601_RS00680
uniprot id: A0A1A9GGI2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1300347:I601 RS01255
gene id: 1300347:I601_RS01255
uniprot id: A0A1A9GG91
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300347:I601 RS01195
gene id: 1300347:I601_RS01195
uniprot id: A0A1A9GEK9
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS13535
gene id: 1300347:I601_RS13535
uniprot id: A0A1A9GLL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1300347:I601 RS11365
gene id: 1300347:I601_RS11365
uniprot id: A0A1A9GKB4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1300347:I601 RS00855
gene id: 1300347:I601_RS00855
uniprot id: A0A1A9GG08
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1300347:I601 RS01280
gene id: 1300347:I601_RS01280
uniprot id: A0A1A9GGV9
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1300347:I601 RS06835
gene id: 1300347:I601_RS06835
uniprot id: A0A1A9GJG7
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

1300347:I601 RS09685
gene id: 1300347:I601_RS09685
uniprot id: A0A1A9GJG0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1300347:I601 RS01900
gene id: 1300347:I601_RS01900
uniprot id: A0A1A9GGN3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300347:I601 RS01530
gene id: 1300347:I601_RS01530
uniprot id: A0A1A9GFB2
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS14160
gene id: 1300347:I601_RS14160
uniprot id: A0A1A9GLX5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1300347:I601 RS14840
gene id: 1300347:I601_RS14840
uniprot id: A0A1A9GM95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1300347:I601 RS05135
gene id: 1300347:I601_RS05135
uniprot id: A0A1A9GGM0
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS16630
gene id: 1300347:I601_RS16630
uniprot id: A0A1A9GNA3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1300347:I601 RS08930
gene id: 1300347:I601_RS08930
uniprot id: A0A1A9GKX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1300347:I601 RS12550
gene id: 1300347:I601_RS12550
uniprot id: A0A1A9GKT7
names: Similarity
messages: Belongs to the DprA/Smf family.

1300347:I601 RS18815
gene id: 1300347:I601_RS18815
uniprot id: A0A1A9GRZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1300347:I601 RS11755
gene id: 1300347:I601_RS11755
uniprot id: A0A1A9GM91
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1300347:I601 RS11310
gene id: 1300347:I601_RS11310
uniprot id: A0A1A9GK47
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1300347:I601 RS07940
gene id: 1300347:I601_RS07940
uniprot id: A0A1A9GIG6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1300347:I601 RS06320
gene id: 1300347:I601_RS06320
uniprot id: A0A1A9GHF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1300347:I601 RS01940
gene id: 1300347:I601_RS01940
uniprot id: A0A1A9GF01
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1300347:I601 RS21905
gene id: 1300347:I601_RS21905
uniprot id: A0A1A9GRP3
names: Subcellular Location Annotation
messages: Cell inner membrane

1300347:I601 RS11845
gene id: 1300347:I601_RS11845
uniprot id: A0A1A9GKK2
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS01070
gene id: 1300347:I601_RS01070
uniprot id: A0A1A9GGC7
names: Similarity
messages: Belongs to the YciI family.

1300347:I601 RS06670
gene id: 1300347:I601_RS06670
uniprot id: A0A1A9GI77
names: Similarity
messages: Belongs to the peptidase M13 family.

1300347:I601 RS05730
gene id: 1300347:I601_RS05730
uniprot id: A0A1A9GH29
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

1300347:I601 RS12945
gene id: 1300347:I601_RS12945
uniprot id: A0A1A9GL13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1300347:I601 RS05905
gene id: 1300347:I601_RS05905
uniprot id: A0A1A9GJ36
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS00810
gene id: 1300347:I601_RS00810
uniprot id: A0A1A9GGG3
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1300347:I601 RS03780
gene id: 1300347:I601_RS03780
uniprot id: A0A1A9GFV5
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

1300347:I601 RS00780
gene id: 1300347:I601_RS00780
uniprot id: A0A1A9GGK3
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

1300347:I601 RS00695
gene id: 1300347:I601_RS00695
uniprot id: A0A1A9GEB8
names: Similarity
messages: Belongs to the PGI/PMI family.

1300347:I601 RS16665
gene id: 1300347:I601_RS16665
uniprot id: A0A1A9GQN3
names: Similarity
messages: Belongs to the UPF0098 family.

1300347:I601 RS09780
gene id: 1300347:I601_RS09780
uniprot id: A0A1A9GLD7
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

1300347:I601 RS02335
gene id: 1300347:I601_RS02335
uniprot id: A0A1A9GF54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1300347:I601 RS03760
gene id: 1300347:I601_RS03760
uniprot id: A0A1A9GID3
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

1300347:I601 RS03310
gene id: 1300347:I601_RS03310
uniprot id: A0A1A9GFL0
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1300347:I601 RS16770
gene id: 1300347:I601_RS16770
uniprot id: A0A1A9GQ72
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1300347:I601 RS18230
gene id: 1300347:I601_RS18230
uniprot id: A0A1A9GP55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1300347:I601 RS02450
gene id: 1300347:I601_RS02450
uniprot id: A0A1A9GGZ5
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

1300347:I601 RS02175
gene id: 1300347:I601_RS02175
uniprot id: A0A1A9GHE8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1300347:I601 RS02355
gene id: 1300347:I601_RS02355
uniprot id: A0A1A9GHD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1300347:I601 RS13305
gene id: 1300347:I601_RS13305
uniprot id: A0A1A9GLD6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

1300347:I601 RS11920
gene id: 1300347:I601_RS11920
uniprot id: A0A1A9GMK2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300347:I601 RS13630
gene id: 1300347:I601_RS13630
uniprot id: A0A1A9GNE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1300347:I601 RS11240
gene id: 1300347:I601_RS11240
uniprot id: A0A1A9GM08
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300347:I601 RS20105
gene id: 1300347:I601_RS20105
uniprot id: A0A1A9GQ81
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1300347:I601 RS20205
gene id: 1300347:I601_RS20205
uniprot id: A0A1A9GQC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1300347:I601 RS17005
gene id: 1300347:I601_RS17005
uniprot id: A0A1A9GQA4
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1300347:I601 RS01275
gene id: 1300347:I601_RS01275
uniprot id: A0A1A9GEP6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1300347:I601 RS01245
gene id: 1300347:I601_RS01245
uniprot id: A0A1A9GEL3
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS01750
gene id: 1300347:I601_RS01750
uniprot id: A0A1A9GH02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1300347:I601 RS14885
gene id: 1300347:I601_RS14885
uniprot id: A0A1A9GM60
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

1300347:I601 RS02220
gene id: 1300347:I601_RS02220
uniprot id: A0A1A9GF73
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1300347:I601 RS07130
gene id: 1300347:I601_RS07130
uniprot id: A0A1A9GHU0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300347:I601 RS01660
gene id: 1300347:I601_RS01660
uniprot id: A0A1A9GGP9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

1300347:I601 RS05975
gene id: 1300347:I601_RS05975
uniprot id: A0A1A9GH78
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1300347:I601 RS15335
gene id: 1300347:I601_RS15335
uniprot id: A0A1A9GMJ7
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1300347:I601 RS06850
gene id: 1300347:I601_RS06850
uniprot id: A0A1A9GJN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

1300347:I601 RS02110
gene id: 1300347:I601_RS02110
uniprot id: A0A1A9GGW5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1300347:I601 RS19245
gene id: 1300347:I601_RS19245
uniprot id: A0A1A9GPM9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1300347:I601 RS03485
gene id: 1300347:I601_RS03485
uniprot id: A0A1A9GHN8
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS04765
gene id: 1300347:I601_RS04765
uniprot id: A0A1A9GH63
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

1300347:I601 RS05060
gene id: 1300347:I601_RS05060
uniprot id: A0A1A9GGV3
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS05255
gene id: 1300347:I601_RS05255
uniprot id: A0A1A9GIQ1
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1300347:I601 RS13490
gene id: 1300347:I601_RS13490
uniprot id: A0A1A9GM40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1300347:I601 RS12470
gene id: 1300347:I601_RS12470
uniprot id: A0A1A9GN79
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1300347:I601 RS06080
gene id: 1300347:I601_RS06080
uniprot id: A0A1A9GH74
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1300347:I601 RS17550
gene id: 1300347:I601_RS17550
uniprot id: A0A1A9GNR5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1300347:I601 RS06720
gene id: 1300347:I601_RS06720
uniprot id: A0A1A9GI86
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1300347:I601 RS13690
gene id: 1300347:I601_RS13690
uniprot id: A0A1A9GLN8
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

1300347:I601 RS19965
gene id: 1300347:I601_RS19965
uniprot id: A0A1A9GRV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1300347:I601 RS19870
gene id: 1300347:I601_RS19870
uniprot id: A0A1A9GSJ0
names: Similarity
messages: Belongs to the CsoR family.

1300347:I601 RS20180
gene id: 1300347:I601_RS20180
uniprot id: A0A1A9GQ84
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

1300347:I601 RS12765
gene id: 1300347:I601_RS12765
uniprot id: A0A1A9GND9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1300347:I601 RS14230
gene id: 1300347:I601_RS14230
uniprot id: A0A1A9GNR1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1300347:I601 RS14910
gene id: 1300347:I601_RS14910
uniprot id: A0A1A9GP38
names: Similarity
messages: Belongs to the group II decarboxylase family.

1300347:I601 RS08415
gene id: 1300347:I601_RS08415
uniprot id: A0A1A9GKY5
names: Similarity
messages: Belongs to the CsoR family.

1300347:I601 RS12465
gene id: 1300347:I601_RS12465
uniprot id: A0A1A9GMN2
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

1300347:I601 RS19020
gene id: 1300347:I601_RS19020
uniprot id: A0A1A9GRJ9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1300347:I601 RS11895
gene id: 1300347:I601_RS11895
uniprot id: A0A1A9GKL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1300347:I601 RS09280
gene id: 1300347:I601_RS09280
uniprot id: A0A1A9GL40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1300347:I601 RS02295
gene id: 1300347:I601_RS02295
uniprot id: A0A1A9GEZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1300347:I601 RS08330
gene id: 1300347:I601_RS08330
uniprot id: A0A1A9GIP3
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1300347:I601 RS11775
gene id: 1300347:I601_RS11775
uniprot id: A0A1A9GKK4
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1300347:I601 RS18305
gene id: 1300347:I601_RS18305
uniprot id: A0A1A9GP74
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1300347:I601 RS12920
gene id: 1300347:I601_RS12920
uniprot id: A0A1A9GMY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1300347:I601 RS05610
gene id: 1300347:I601_RS05610
uniprot id: A0A1A9GH60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1300347:I601 RS16900
gene id: 1300347:I601_RS16900
uniprot id: A0A1A9GND5
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1300347:I601 RS15235
gene id: 1300347:I601_RS15235
uniprot id: A0A1A9GMH8
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1300347:I601 RS14605
gene id: 1300347:I601_RS14605
uniprot id: A0A1A9GPF6
names: Similarity
messages: Belongs to the carbamate kinase family.

1300347:I601 RS19195
gene id: 1300347:I601_RS19195
uniprot id: A0A1A9GPL9
names: Similarity
names: Subunit
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Monomer.

1300347:I601 RS06810
gene id: 1300347:I601_RS06810
uniprot id: A0A1A9GK33
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS02950
gene id: 1300347:I601_RS02950
uniprot id: A0A1A9GH95
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1300347:I601 RS14215
gene id: 1300347:I601_RS14215
uniprot id: A0A1A9GLX4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1300347:I601 RS02455
gene id: 1300347:I601_RS02455
uniprot id: A0A1A9GHF1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1300347:I601 RS17435
gene id: 1300347:I601_RS17435
uniprot id: A0A1A9GPB6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1300347:I601 RS13425
gene id: 1300347:I601_RS13425
uniprot id: A0A1A9GNG0
names: Similarity
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.

1300347:I601 RS12080
gene id: 1300347:I601_RS12080
uniprot id: A0A1A9GN32
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1300347:I601 RS19510
gene id: 1300347:I601_RS19510
uniprot id: A0A1A9GRP5
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1300347:I601 RS12820
gene id: 1300347:I601_RS12820
uniprot id: A0A1A9GMW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1300347:I601 RS07380
gene id: 1300347:I601_RS07380
uniprot id: A0A1A9GHZ1
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1300347:I601 RS18920
gene id: 1300347:I601_RS18920
uniprot id: A0A1A9GRI6
names: Similarity
messages: Belongs to the TPP enzyme family.

1300347:I601 RS06180
gene id: 1300347:I601_RS06180
uniprot id: A0A1A9GJ23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

1300347:I601 RS11140
gene id: 1300347:I601_RS11140
uniprot id: A0A1A9GM54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1300347:I601 RS02240
gene id: 1300347:I601_RS02240
uniprot id: A0A1A9GF59
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1300347:I601 RS13610
gene id: 1300347:I601_RS13610
uniprot id: A0A1A9GLM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1300347:I601 RS18630
gene id: 1300347:I601_RS18630
uniprot id: A0A1A9GRC0
names: Similarity
messages: Belongs to the Fur family.

1300347:I601 RS00950
gene id: 1300347:I601_RS00950
uniprot id: A0A1A9GG28
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

1300347:I601 RS14730
gene id: 1300347:I601_RS14730
uniprot id: A0A1A9GMT1
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1300347:I601 RS02940
gene id: 1300347:I601_RS02940
uniprot id: A0A1A9GFJ4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1300347:I601 RS13135
gene id: 1300347:I601_RS13135
uniprot id: A0A1A9GNQ4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300347:I601 RS17495
gene id: 1300347:I601_RS17495
uniprot id: A0A1A9GNS0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1300347:I601 RS12320
gene id: 1300347:I601_RS12320
uniprot id: A0A1A9GML6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1300347:I601 RS18215
gene id: 1300347:I601_RS18215
uniprot id: A0A1A9GPT2
names: Similarity
messages: Belongs to the glutamate synthase family.

1300347:I601 RS00270
gene id: 1300347:I601_RS00270
uniprot id: A0A1A9GGA2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1300347:I601 RS06310
gene id: 1300347:I601_RS06310
uniprot id: A0A1A9GI08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1300347:I601 RS03455
gene id: 1300347:I601_RS03455
uniprot id: A0A1A9GGG1
names: Similarity
messages: Belongs to the citrate synthase family.

1300347:I601 RS15025
gene id: 1300347:I601_RS15025
uniprot id: A0A1A9GPS8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1300347:I601 RS07755
gene id: 1300347:I601_RS07755
uniprot id: A0A1A9GI48
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1300347:I601 RS10425
gene id: 1300347:I601_RS10425
uniprot id: A0A1A9GLH4
names: Similarity
messages: Belongs to the PrpD family.

1300347:I601 RS06460
gene id: 1300347:I601_RS06460
uniprot id: A0A1A9GHM3
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS19480
gene id: 1300347:I601_RS19480
uniprot id: A0A1A9GPU7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1300347:I601 RS03985
gene id: 1300347:I601_RS03985
uniprot id: A0A1A9GFZ5
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS14620
gene id: 1300347:I601_RS14620
uniprot id: A0A1A9GM57
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS19300
gene id: 1300347:I601_RS19300
uniprot id: A0A1A9GPT6
names: Similarity
messages: Belongs to the peptidase S8 family.

1300347:I601 RS10140
gene id: 1300347:I601_RS10140
uniprot id: A0A1A9GJP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1300347:I601 RS20370
gene id: 1300347:I601_RS20370
uniprot id: A0A1A9GS86
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1300347:I601 RS01615
gene id: 1300347:I601_RS01615
uniprot id: A0A1A9GEW1
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

1300347:I601 RS08205
gene id: 1300347:I601_RS08205
uniprot id: A0A1A9GIE8
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS18420
gene id: 1300347:I601_RS18420
uniprot id: A0A1A9GPX4
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1300347:I601 RS02070
gene id: 1300347:I601_RS02070
uniprot id: A0A1A9GF46
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1300347:I601 RS03685
gene id: 1300347:I601_RS03685
uniprot id: A0A1A9GHS6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1300347:I601 RS09410
gene id: 1300347:I601_RS09410
uniprot id: A0A1A9GKY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1300347:I601 RS02350
gene id: 1300347:I601_RS02350
uniprot id: A0A1A9GGX8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1300347:I601 RS14595
gene id: 1300347:I601_RS14595
uniprot id: A0A1A9GM37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AmiS/UreI family.
messages: Membrane

1300347:I601 RS07010
gene id: 1300347:I601_RS07010
uniprot id: A0A1A9GJR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1300347:I601 RS02310
gene id: 1300347:I601_RS02310
uniprot id: A0A1A9GH06
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1300347:I601 RS18270
gene id: 1300347:I601_RS18270
uniprot id: A0A1A9GP48
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1300347:I601 RS19325
gene id: 1300347:I601_RS19325
uniprot id: A0A1A9GRN0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1300347:I601 RS18545
gene id: 1300347:I601_RS18545
uniprot id: A0A1A9GPZ4
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

1300347:I601 RS18910
gene id: 1300347:I601_RS18910
uniprot id: A0A1A9GRG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1300347:I601 RS06285
gene id: 1300347:I601_RS06285
uniprot id: A0A1A9GJN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1300347:I601 RS10135
gene id: 1300347:I601_RS10135
uniprot id: A0A1A9GLK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1300347:I601 RS04055
gene id: 1300347:I601_RS04055
uniprot id: A0A1A9GI31
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1300347:I601 RS08250
gene id: 1300347:I601_RS08250
uniprot id: A0A1A9GIK3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1300347:I601 RS11145
gene id: 1300347:I601_RS11145
uniprot id: A0A1A9GK86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

1300347:I601 RS03825
gene id: 1300347:I601_RS03825
uniprot id: A0A1A9GG03
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1300347:I601 RS02945
gene id: 1300347:I601_RS02945
uniprot id: A0A1A9GFE5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1300347:I601 RS02065
gene id: 1300347:I601_RS02065
uniprot id: A0A1A9GGY6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1300347:I601 RS07000
gene id: 1300347:I601_RS07000
uniprot id: A0A1A9GK39
names: Similarity
messages: Belongs to the peptidase M1 family.

1300347:I601 RS10050
gene id: 1300347:I601_RS10050
uniprot id: A0A1A9GK57
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1300347:I601 RS02190
gene id: 1300347:I601_RS02190
uniprot id: A0A1A9GF50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1300347:I601 RS16895
gene id: 1300347:I601_RS16895
uniprot id: A0A1A9GNE6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

1300347:I601 RS07845
gene id: 1300347:I601_RS07845
uniprot id: A0A1A9GI76
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1300347:I601 RS13615
gene id: 1300347:I601_RS13615
uniprot id: A0A1A9GLK5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1300347:I601 RS01180
gene id: 1300347:I601_RS01180
uniprot id: A0A1A9GGT6
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1300347:I601 RS12380
gene id: 1300347:I601_RS12380
uniprot id: A0A1A9GMU3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1300347:I601 RS20025
gene id: 1300347:I601_RS20025
uniprot id: A0A1A9GS75
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1300347:I601 RS11635
gene id: 1300347:I601_RS11635
uniprot id: A0A1A9GKG3
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300347:I601 RS01820
gene id: 1300347:I601_RS01820
uniprot id: A0A1A9GEZ7
names: Similarity
messages: Belongs to the stealth family.

1300347:I601 RS06275
gene id: 1300347:I601_RS06275
uniprot id: A0A1A9GHB0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1300347:I601 RS18235
gene id: 1300347:I601_RS18235
uniprot id: A0A1A9GQZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1300347:I601 RS10660
gene id: 1300347:I601_RS10660
uniprot id: A0A1A9GJS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

1300347:I601 RS19430
gene id: 1300347:I601_RS19430
uniprot id: A0A1A9GPU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1300347:I601 RS01665
gene id: 1300347:I601_RS01665
uniprot id: A0A1A9GEW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1300347:I601 RS14325
gene id: 1300347:I601_RS14325
uniprot id: A0A1A9GPA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1300347:I601 RS14845
gene id: 1300347:I601_RS14845
uniprot id: A0A1A9GM87
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1300347:I601 RS15260
gene id: 1300347:I601_RS15260
uniprot id: A0A1A9GMH6
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

1300347:I601 RS04365
gene id: 1300347:I601_RS04365
uniprot id: A0A1A9GIP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1300347:I601 RS12905
gene id: 1300347:I601_RS12905
uniprot id: A0A1A9GL56
names: Similarity
messages: Belongs to the ribF family.

1300347:I601 RS11940
gene id: 1300347:I601_RS11940
uniprot id: A0A1A9GKG8
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1300347:I601 RS16420
gene id: 1300347:I601_RS16420
uniprot id: A0A1A9GQ50
names: Caution
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

1300347:I601 RS05045
gene id: 1300347:I601_RS05045
uniprot id: A0A1A9GIX5
names: Similarity
messages: Belongs to the peptidase S51 family.

1300347:I601 RS02260
gene id: 1300347:I601_RS02260
uniprot id: A0A1A9GGZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1300347:I601 RS02265
gene id: 1300347:I601_RS02265
uniprot id: A0A1A9GH27
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1300347:I601 RS03120
gene id: 1300347:I601_RS03120
uniprot id: A0A1A9GHG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

1300347:I601 RS12630
gene id: 1300347:I601_RS12630
uniprot id: A0A1A9GL26
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1300347:I601 RS06150
gene id: 1300347:I601_RS06150
uniprot id: A0A1A9GJ93
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300347:I601 RS03845
gene id: 1300347:I601_RS03845
uniprot id: A0A1A9GI87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1300347:I601 RS21005
gene id: 1300347:I601_RS21005
uniprot id: A0A1A9GG43
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1300347:I601 RS02365
gene id: 1300347:I601_RS02365
uniprot id: A0A1A9GH47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1300347:I601 RS12345
gene id: 1300347:I601_RS12345
uniprot id: A0A1A9GLE4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1300347:I601 RS14505
gene id: 1300347:I601_RS14505
uniprot id: A0A1A9GMP2
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

1300347:I601 RS01380
gene id: 1300347:I601_RS01380
uniprot id: A0A1A9GGX7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1300347:I601 RS00655
gene id: 1300347:I601_RS00655
uniprot id: A0A1A9GFW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1300347:I601 RS11780
gene id: 1300347:I601_RS11780
uniprot id: A0A1A9GMX0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1300347:I601 RS05035
gene id: 1300347:I601_RS05035
uniprot id: A0A1A9GGK1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1300347:I601 RS19890
gene id: 1300347:I601_RS19890
uniprot id: A0A1A9GSG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1300347:I601 RS09020
gene id: 1300347:I601_RS09020
uniprot id: A0A1A9GKS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1300347:I601 RS14320
gene id: 1300347:I601_RS14320
uniprot id: A0A1A9GNR7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1300347:I601 RS19440
gene id: 1300347:I601_RS19440
uniprot id: A0A1A9GQI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1300347:I601 RS08780
gene id: 1300347:I601_RS08780
uniprot id: A0A1A9GKV0
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300347:I601 RS19945
gene id: 1300347:I601_RS19945
uniprot id: A0A1A9GQQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1300347:I601 RS14765
gene id: 1300347:I601_RS14765
uniprot id: A0A1A9GP62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1300347:I601 RS14080
gene id: 1300347:I601_RS14080
uniprot id: A0A1A9GNN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

1300347:I601 RS00450
gene id: 1300347:I601_RS00450
uniprot id: A0A1A9GE11
names: Similarity
messages: Belongs to the AHA1 family.

1300347:I601 RS12560
gene id: 1300347:I601_RS12560
uniprot id: A0A1A9GMQ9
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1300347:I601 RS17680
gene id: 1300347:I601_RS17680
uniprot id: A0A1A9GNR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1300347:I601 RS11885
gene id: 1300347:I601_RS11885
uniprot id: A0A1A9GL52
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1300347:I601 RS07125
gene id: 1300347:I601_RS07125
uniprot id: A0A1A9GIG8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1300347:I601 RS07865
gene id: 1300347:I601_RS07865
uniprot id: A0A1A9GKL8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1300347:I601 RS03035
gene id: 1300347:I601_RS03035
uniprot id: A0A1A9GFK0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1300347:I601 RS12420
gene id: 1300347:I601_RS12420
uniprot id: A0A1A9GN70
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1300347:I601 RS17655
gene id: 1300347:I601_RS17655
uniprot id: A0A1A9GQQ5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1300347:I601 RS20250
gene id: 1300347:I601_RS20250
uniprot id: A0A1A9GQ60
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS20400
gene id: 1300347:I601_RS20400
uniprot id: A0A1A9GQD9
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS03735
gene id: 1300347:I601_RS03735
uniprot id: A0A1A9GHQ8
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS01950
gene id: 1300347:I601_RS01950
uniprot id: A0A1A9GGP3
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

1300347:I601 RS15170
gene id: 1300347:I601_RS15170
uniprot id: A0A1A9GMG8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1300347:I601 RS07365
gene id: 1300347:I601_RS07365
uniprot id: A0A1A9GI57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1300347:I601 RS09985
gene id: 1300347:I601_RS09985
uniprot id: A0A1A9GLH3
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1300347:I601 RS12975
gene id: 1300347:I601_RS12975
uniprot id: A0A1A9GN66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

1300347:I601 RS05755
gene id: 1300347:I601_RS05755
uniprot id: A0A1A9GJ03
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1300347:I601 RS04745
gene id: 1300347:I601_RS04745
uniprot id: A0A1A9GIB4
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS00700
gene id: 1300347:I601_RS00700
uniprot id: A0A1A9GE58
names: Similarity
messages: Belongs to the UPF0434 family.

1300347:I601 RS19415
gene id: 1300347:I601_RS19415
uniprot id: A0A1A9GS98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1300347:I601 RS02600
gene id: 1300347:I601_RS02600
uniprot id: A0A1A9GH22
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1300347:I601 RS15135
gene id: 1300347:I601_RS15135
uniprot id: A0A1A9GMA9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1300347:I601 RS12555
gene id: 1300347:I601_RS12555
uniprot id: A0A1A9GKZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1300347:I601 RS13330
gene id: 1300347:I601_RS13330
uniprot id: A0A1A9GLG3
names: Similarity
messages: Belongs to the threonine aldolase family.

1300347:I601 RS13485
gene id: 1300347:I601_RS13485
uniprot id: A0A1A9GNX7
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300347:I601 RS04570
gene id: 1300347:I601_RS04570
uniprot id: A0A1A9GH30
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1300347:I601 RS03115
gene id: 1300347:I601_RS03115
uniprot id: A0A1A9GHT5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

1300347:I601 RS14125
gene id: 1300347:I601_RS14125
uniprot id: A0A1A9GP70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1300347:I601 RS05315
gene id: 1300347:I601_RS05315
uniprot id: A0A1A9GJ77
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1300347:I601 RS08450
gene id: 1300347:I601_RS08450
uniprot id: A0A1A9GIP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1300347:I601 RS11965
gene id: 1300347:I601_RS11965
uniprot id: A0A1A9GME0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1300347:I601 RS09140
gene id: 1300347:I601_RS09140
uniprot id: A0A1A9GJP1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1300347:I601 RS07825
gene id: 1300347:I601_RS07825
uniprot id: A0A1A9GK92
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1300347:I601 RS14750
gene id: 1300347:I601_RS14750
uniprot id: A0A1A9GP03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

1300347:I601 RS10110
gene id: 1300347:I601_RS10110
uniprot id: A0A1A9GJN3
names: Function
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1300347:I601 RS13320
gene id: 1300347:I601_RS13320
uniprot id: A0A1A9GN76
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS02380
gene id: 1300347:I601_RS02380
uniprot id: A0A1A9GFV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

1300347:I601 RS03205
gene id: 1300347:I601_RS03205
uniprot id: A0A1A9GFI9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1300347:I601 RS10115
gene id: 1300347:I601_RS10115
uniprot id: A0A1A9GJL3
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

1300347:I601 RS03775
gene id: 1300347:I601_RS03775
uniprot id: A0A1A9GG17
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

1300347:I601 RS01320
gene id: 1300347:I601_RS01320
uniprot id: A0A1A9GGH3
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1300347:I601 RS06395
gene id: 1300347:I601_RS06395
uniprot id: A0A1A9GJ85
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1300347:I601 RS07325
gene id: 1300347:I601_RS07325
uniprot id: A0A1A9GIK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

1300347:I601 RS12355
gene id: 1300347:I601_RS12355
uniprot id: A0A1A9GKV1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1300347:I601 RS12895
gene id: 1300347:I601_RS12895
uniprot id: A0A1A9GL05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1300347:I601 RS01775
gene id: 1300347:I601_RS01775
uniprot id: A0A1A9GFI1
names: Similarity
messages: Belongs to the peptidase M1 family.

1300347:I601 RS03490
gene id: 1300347:I601_RS03490
uniprot id: A0A1A9GHS8
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS10255
gene id: 1300347:I601_RS10255
uniprot id: A0A1A9GJR4
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1300347:I601 RS03330
gene id: 1300347:I601_RS03330
uniprot id: A0A1A9GHN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscL family.
messages: Membrane

1300347:I601 RS12215
gene id: 1300347:I601_RS12215
uniprot id: A0A1A9GMR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1300347:I601 RS14155
gene id: 1300347:I601_RS14155
uniprot id: A0A1A9GLS2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1300347:I601 RS14195
gene id: 1300347:I601_RS14195
uniprot id: A0A1A9GPC1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

1300347:I601 RS14025
gene id: 1300347:I601_RS14025
uniprot id: A0A1A9GNK8
names: Similarity
messages: Belongs to the thioredoxin family. DsbE subfamily.

1300347:I601 RS07110
gene id: 1300347:I601_RS07110
uniprot id: A0A1A9GJT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1300347:I601 RS13235
gene id: 1300347:I601_RS13235
uniprot id: A0A1A9GNS6
names: Similarity
messages: Belongs to the arsA ATPase family.

1300347:I601 RS19465
gene id: 1300347:I601_RS19465
uniprot id: A0A1A9GSB1
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS13980
gene id: 1300347:I601_RS13980
uniprot id: A0A1A9GP41
names: Subcellular Location Annotation
messages: Cell membrane

1300347:I601 RS02850
gene id: 1300347:I601_RS02850
uniprot id: A0A1A9GH77
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

1300347:I601 RS02505
gene id: 1300347:I601_RS02505
uniprot id: A0A1A9GHG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1300347:I601 RS18570
gene id: 1300347:I601_RS18570
uniprot id: A0A1A9GRT2
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS13520
gene id: 1300347:I601_RS13520
uniprot id: A0A1A9GNV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1300347:I601 RS08265
gene id: 1300347:I601_RS08265
uniprot id: A0A1A9GKV4
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1300347:I601 RS10740
gene id: 1300347:I601_RS10740
uniprot id: A0A1A9GK14
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1300347:I601 RS02285
gene id: 1300347:I601_RS02285
uniprot id: A0A1A9GF47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1300347:I601 RS09690
gene id: 1300347:I601_RS09690
uniprot id: A0A1A9GLR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1300347:I601 RS11950
gene id: 1300347:I601_RS11950
uniprot id: A0A1A9GKL0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1300347:I601 RS11890
gene id: 1300347:I601_RS11890
uniprot id: A0A1A9GKF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1300347:I601 RS14110
gene id: 1300347:I601_RS14110
uniprot id: A0A1A9GLV4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1300347:I601 RS08220
gene id: 1300347:I601_RS08220
uniprot id: A0A1A9GKA8
names: Similarity
messages: Belongs to the peptidase S13 family.

1300347:I601 RS11410
gene id: 1300347:I601_RS11410
uniprot id: A0A1A9GK65
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1300347:I601 RS18985
gene id: 1300347:I601_RS18985
uniprot id: A0A1A9GRV6
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

1300347:I601 RS01085
gene id: 1300347:I601_RS01085
uniprot id: A0A1A9GF28
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1300347:I601 RS15885
gene id: 1300347:I601_RS15885
uniprot id: A0A1A9GQ57
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300347:I601 RS04610
gene id: 1300347:I601_RS04610
uniprot id: A0A1A9GGL3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1300347:I601 RS08955
gene id: 1300347:I601_RS08955
uniprot id: A0A1A9GJ06
names: Similarity
messages: Belongs to the TPP enzyme family.

1300347:I601 RS16690
gene id: 1300347:I601_RS16690
uniprot id: A0A1A9GNW3
names: Similarity
messages: Belongs to the catalase family.

1300347:I601 RS13540
gene id: 1300347:I601_RS13540
uniprot id: A0A1A9GNZ8
names: Similarity
messages: Belongs to the YggT family.

1300347:I601 RS17645
gene id: 1300347:I601_RS17645
uniprot id: A0A1A9GQN6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1300347:I601 RS00590
gene id: 1300347:I601_RS00590
uniprot id: A0A1A9GE71
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1300347:I601 RS04030
gene id: 1300347:I601_RS04030
uniprot id: A0A1A9GG58
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1300347:I601 RS12410
gene id: 1300347:I601_RS12410
uniprot id: A0A1A9GKV2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1300347:I601 RS12060
gene id: 1300347:I601_RS12060
uniprot id: A0A1A9GMZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.

1300347:I601 RS17810
gene id: 1300347:I601_RS17810
uniprot id: A0A1A9GQX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1300347:I601 RS00930
gene id: 1300347:I601_RS00930
uniprot id: A0A1A9GEZ9
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS06705
gene id: 1300347:I601_RS06705
uniprot id: A0A1A9GJK6
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

1300347:I601 RS16715
gene id: 1300347:I601_RS16715
uniprot id: A0A1A9GQP5
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS12185
gene id: 1300347:I601_RS12185
uniprot id: A0A1A9GKL5
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1300347:I601 RS02675
gene id: 1300347:I601_RS02675
uniprot id: A0A1A9GHP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1300347:I601 RS00820
gene id: 1300347:I601_RS00820
uniprot id: A0A1A9GG77
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1300347:I601 RS10750
gene id: 1300347:I601_RS10750
uniprot id: A0A1A9GKJ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1300347:I601 RS08500
gene id: 1300347:I601_RS08500
uniprot id: A0A1A9GIQ5
names: Similarity
messages: Belongs to the Fur family.

1300347:I601 RS15115
gene id: 1300347:I601_RS15115
uniprot id: A0A1A9GPC8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1300347:I601 RS10855
gene id: 1300347:I601_RS10855
uniprot id: A0A1A9GJW3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1300347:I601 RS12890
gene id: 1300347:I601_RS12890
uniprot id: A0A1A9GLQ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1300347:I601 RS08960
gene id: 1300347:I601_RS08960
uniprot id: A0A1A9GIV9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1300347:I601 RS00805
gene id: 1300347:I601_RS00805
uniprot id: A0A1A9GFZ8
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1300347:I601 RS17275
gene id: 1300347:I601_RS17275
uniprot id: A0A1A9GNM6
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

1300347:I601 RS18080
gene id: 1300347:I601_RS18080
uniprot id: A0A1A9GP01
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS16740
gene id: 1300347:I601_RS16740
uniprot id: A0A1A9GNX3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1300347:I601 RS03265
gene id: 1300347:I601_RS03265
uniprot id: A0A1A9GHW8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1300347:I601 RS04945
gene id: 1300347:I601_RS04945
uniprot id: A0A1A9GIF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Membrane

1300347:I601 RS19655
gene id: 1300347:I601_RS19655
uniprot id: A0A1A9GPZ1
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1300347:I601 RS13760
gene id: 1300347:I601_RS13760
uniprot id: A0A1A9GLJ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1300347:I601 RS06300
gene id: 1300347:I601_RS06300
uniprot id: A0A1A9GHJ4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1300347:I601 RS09655
gene id: 1300347:I601_RS09655
uniprot id: A0A1A9GJE7
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1300347:I601 RS19930
gene id: 1300347:I601_RS19930
uniprot id: A0A1A9GRZ8
names: Similarity
messages: Belongs to the thioredoxin family.

1300347:I601 RS10845
gene id: 1300347:I601_RS10845
uniprot id: A0A1A9GME1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300347:I601 RS03660
gene id: 1300347:I601_RS03660
uniprot id: A0A1A9GFZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1300347:I601 RS03800
gene id: 1300347:I601_RS03800
uniprot id: A0A1A9GHU8
names: Similarity
messages: Belongs to the UPF0234 family.

1300347:I601 RS13015
gene id: 1300347:I601_RS13015
uniprot id: A0A1A9GNJ3
names: Similarity
messages: Belongs to the PspA/IM30 family.

1300347:I601 RS14275
gene id: 1300347:I601_RS14275
uniprot id: A0A1A9GP98
names: Similarity
messages: Belongs to the GcvT family.

1300347:I601 RS09705
gene id: 1300347:I601_RS09705
uniprot id: A0A1A9GJF7
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1300347:I601 RS15180
gene id: 1300347:I601_RS15180
uniprot id: A0A1A9GN20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1300347:I601 RS09925
gene id: 1300347:I601_RS09925
uniprot id: A0A1A9GLT2
names: Similarity
messages: Belongs to the IMPACT family.

1300347:I601 RS09650
gene id: 1300347:I601_RS09650
uniprot id: A0A1A9GJ82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1300347:I601 RS03075
gene id: 1300347:I601_RS03075
uniprot id: A0A1A9GHY7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1300347:I601 RS05345
gene id: 1300347:I601_RS05345
uniprot id: A0A1A9GJ47
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1300347:I601 RS19125
gene id: 1300347:I601_RS19125
uniprot id: A0A1A9GRM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1300347:I601 RS11485
gene id: 1300347:I601_RS11485
uniprot id: A0A1A9GMN5
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS11570
gene id: 1300347:I601_RS11570
uniprot id: A0A1A9GKZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1300347:I601 RS16065
gene id: 1300347:I601_RS16065
uniprot id: A0A1A9GMY0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1300347:I601 RS16330
gene id: 1300347:I601_RS16330
uniprot id: A0A1A9GN44
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1300347:I601 RS04445
gene id: 1300347:I601_RS04445
uniprot id: A0A1A9GIL1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1300347:I601 RS13435
gene id: 1300347:I601_RS13435
uniprot id: A0A1A9GNW5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1300347:I601 RS07630
gene id: 1300347:I601_RS07630
uniprot id: A0A1A9GK44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

1300347:I601 RS05175
gene id: 1300347:I601_RS05175
uniprot id: A0A1A9GGR2
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS17105
gene id: 1300347:I601_RS17105
uniprot id: A0A1A9GQC5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1300347:I601 RS18735
gene id: 1300347:I601_RS18735
uniprot id: A0A1A9GPF8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

1300347:I601 RS07580
gene id: 1300347:I601_RS07580
uniprot id: A0A1A9GI97
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

1300347:I601 RS01535
gene id: 1300347:I601_RS01535
uniprot id: A0A1A9GEQ7
names: Function
names: Similarity
messages: Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
messages: In the C-terminal section; belongs to the radical SAM superfamily. CofH family.
messages: In the N-terminal section; belongs to the radical SAM superfamily. CofG family.

1300347:I601 RS13050
gene id: 1300347:I601_RS13050
uniprot id: A0A1A9GL98
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1300347:I601 RS04110
gene id: 1300347:I601_RS04110
uniprot id: A0A1A9GIK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1300347:I601 RS14715
gene id: 1300347:I601_RS14715
uniprot id: A0A1A9GP57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1300347:I601 RS13815
gene id: 1300347:I601_RS13815
uniprot id: A0A1A9GLQ9
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

1300347:I601 RS03215
gene id: 1300347:I601_RS03215
uniprot id: A0A1A9GHV7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1300347:I601 RS05550
gene id: 1300347:I601_RS05550
uniprot id: A0A1A9GIR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1300347:I601 RS15160
gene id: 1300347:I601_RS15160
uniprot id: A0A1A9GP82
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

1300347:I601 RS03740
gene id: 1300347:I601_RS03740
uniprot id: A0A1A9GI70
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS01625
gene id: 1300347:I601_RS01625
uniprot id: A0A1A9GFE7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1300347:I601 RS14815
gene id: 1300347:I601_RS14815
uniprot id: A0A1A9GP73
names: Similarity
messages: Belongs to the peptidase A24 family.

1300347:I601 RS10615
gene id: 1300347:I601_RS10615
uniprot id: A0A1A9GJY2
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1300347:I601 RS14420
gene id: 1300347:I601_RS14420
uniprot id: A0A1A9GM14
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS12205
gene id: 1300347:I601_RS12205
uniprot id: A0A1A9GN29
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS05430
gene id: 1300347:I601_RS05430
uniprot id: A0A1A9GGX9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1300347:I601 RS19960
gene id: 1300347:I601_RS19960
uniprot id: A0A1A9GQ52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1300347:I601 RS09965
gene id: 1300347:I601_RS09965
uniprot id: A0A1A9GJI1
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1300347:I601 RS20090
gene id: 1300347:I601_RS20090
uniprot id: A0A1A9GSK0
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1300347:I601 RS11355
gene id: 1300347:I601_RS11355
uniprot id: A0A1A9GKV7
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS10990
gene id: 1300347:I601_RS10990
uniprot id: A0A1A9GK59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1300347:I601 RS19515
gene id: 1300347:I601_RS19515
uniprot id: A0A1A9GSC3
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1300347:I601 RS16435
gene id: 1300347:I601_RS16435
uniprot id: A0A1A9GNQ8
names: Similarity
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Homohexamer. Assembles into a hexameric ring structure.

1300347:I601 RS12220
gene id: 1300347:I601_RS12220
uniprot id: A0A1A9GKU5
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

1300347:I601 RS16115
gene id: 1300347:I601_RS16115
uniprot id: A0A1A9GMZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1300347:I601 RS05790
gene id: 1300347:I601_RS05790
uniprot id: A0A1A9GIU3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1300347:I601 RS15820
gene id: 1300347:I601_RS15820
uniprot id: A0A1A9GMS7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NnrE/AIBP family.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300347:I601 RS02185
gene id: 1300347:I601_RS02185
uniprot id: A0A1A9GF27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1300347:I601 RS17025
gene id: 1300347:I601_RS17025
uniprot id: A0A1A9GNH7
names: Function
names: Subcellular Location Annotation
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

1300347:I601 RS15250
gene id: 1300347:I601_RS15250
uniprot id: A0A1A9GME4
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300347:I601 RS08865
gene id: 1300347:I601_RS08865
uniprot id: A0A1A9GKM8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1300347:I601 RS21580
gene id: 1300347:I601_RS21580
uniprot id: A0A1A9GPN8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

1300347:I601 RS06315
gene id: 1300347:I601_RS06315
uniprot id: A0A1A9GHE0
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

1300347:I601 RS01215
gene id: 1300347:I601_RS01215
uniprot id: A0A1A9GGD7
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

1300347:I601 RS18995
gene id: 1300347:I601_RS18995
uniprot id: A0A1A9GPI0
names: Similarity
messages: Belongs to the CobH/CbiC family.

1300347:I601 RS17985
gene id: 1300347:I601_RS17985
uniprot id: A0A1A9GP19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

1300347:I601 RS18350
gene id: 1300347:I601_RS18350
uniprot id: A0A1A9GR67
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.
messages: Belongs to the fatty acyl-CoA reductase family.

1300347:I601 RS06535
gene id: 1300347:I601_RS06535
uniprot id: A0A1A9GHF9
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cyclic amide hydrolase (CyAH) family.
messages: Homotetramer.
messages: Inhibited by cyanuric acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Responsible for the hydrolysis of barbituric acid (2,4,6-trihydroxy-1,3-pyrimidine), an intermediate in the oxidative catabolism of pyrimidines. Catalyzes the hydrolytic opening of the pyrimidine ring of barbituric acid to yield ureidomalonic acid.
messages: The monomer structure is formed from three repeating units (RUs) that share the same structure as one another. The monomer and the active site possess nearly threefold rotational symmetry, to the extent that the active site possesses three potential Ser-Lys catalytic dyads, but one of the 3 active site surfaces varies in composition suggesting it is involved in confering substrate specificity.

1300347:I601 RS02925
gene id: 1300347:I601_RS02925
uniprot id: A0A1A9GHV3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1300347:I601 RS17735
gene id: 1300347:I601_RS17735
uniprot id: A0A1A9GNW9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1300347:I601 RS01590
gene id: 1300347:I601_RS01590
uniprot id: A0A1A9GET0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1300347:I601 RS06145
gene id: 1300347:I601_RS06145
uniprot id: A0A1A9GJ39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1300347:I601 RS07765
gene id: 1300347:I601_RS07765
uniprot id: A0A1A9GKJ6
names: Similarity
messages: Belongs to the GSP E family.

1300347:I601 RS11930
gene id: 1300347:I601_RS11930
uniprot id: A0A1A9GN05
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS18645
gene id: 1300347:I601_RS18645
uniprot id: A0A1A9GQ22
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1300347:I601 RS08940
gene id: 1300347:I601_RS08940
uniprot id: A0A1A9GLC1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1300347:I601 RS06000
gene id: 1300347:I601_RS06000
uniprot id: A0A1A9GJ56
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS11830
gene id: 1300347:I601_RS11830
uniprot id: A0A1A9GMY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1300347:I601 RS14260
gene id: 1300347:I601_RS14260
uniprot id: A0A1A9GLZ4
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1300347:I601 RS12745
gene id: 1300347:I601_RS12745
uniprot id: A0A1A9GKX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1300347:I601 RS19070
gene id: 1300347:I601_RS19070
uniprot id: A0A1A9GRL3
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

1300347:I601 RS06370
gene id: 1300347:I601_RS06370
uniprot id: A0A1A9GHF0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300347:I601 RS06980
gene id: 1300347:I601_RS06980
uniprot id: A0A1A9GHT7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

1300347:I601 RS04155
gene id: 1300347:I601_RS04155
uniprot id: A0A1A9GGC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions.

1300347:I601 RS04415
gene id: 1300347:I601_RS04415
uniprot id: A0A1A9GIQ6
names: Similarity
messages: Belongs to the FPG family.

1300347:I601 RS00705
gene id: 1300347:I601_RS00705
uniprot id: A0A1A9GFX6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1300347:I601 RS00840
gene id: 1300347:I601_RS00840
uniprot id: A0A1A9GEC7
names: Similarity
messages: Belongs to the Dps family.

1300347:I601 RS03200
gene id: 1300347:I601_RS03200
uniprot id: A0A1A9GFP7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1300347:I601 RS12375
gene id: 1300347:I601_RS12375
uniprot id: A0A1A9GMM8
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1300347:I601 RS19710
gene id: 1300347:I601_RS19710
uniprot id: A0A1A9GRR9
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1300347:I601 RS10530
gene id: 1300347:I601_RS10530
uniprot id: A0A1A9GM52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

1300347:I601 RS06335
gene id: 1300347:I601_RS06335
uniprot id: A0A1A9GJQ1
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

1300347:I601 RS06245
gene id: 1300347:I601_RS06245
uniprot id: A0A1A9GJB2
names: Similarity
messages: Belongs to the thioredoxin family.

1300347:I601 RS02605
gene id: 1300347:I601_RS02605
uniprot id: A0A1A9GHI1
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

1300347:I601 RS11815
gene id: 1300347:I601_RS11815
uniprot id: A0A1A9GMC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1300347:I601 RS03980
gene id: 1300347:I601_RS03980
uniprot id: A0A1A9GG52
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS19505
gene id: 1300347:I601_RS19505
uniprot id: A0A1A9GPW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1300347:I601 RS16100
gene id: 1300347:I601_RS16100
uniprot id: A0A1A9GNJ6
names: Similarity
messages: Belongs to the peptidase U62 family.

1300347:I601 RS02245
gene id: 1300347:I601_RS02245
uniprot id: A0A1A9GEY8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1300347:I601 RS15325
gene id: 1300347:I601_RS15325
uniprot id: A0A1A9GPB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1300347:I601 RS12155
gene id: 1300347:I601_RS12155
uniprot id: A0A1A9GMG9
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1300347:I601 RS01575
gene id: 1300347:I601_RS01575
uniprot id: A0A1A9GH12
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1300347:I601 RS06640
gene id: 1300347:I601_RS06640
uniprot id: A0A1A9GJC5
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS06925
gene id: 1300347:I601_RS06925
uniprot id: A0A1A9GHS7
names: Similarity
names: Subunit
messages: Belongs to the Bpa family.
messages: Forms a homooligomeric, either hexameric or heptameric, ring-like structure which stacks co-axially with the proteasomal alpha-rings.

1300347:I601 RS07690
gene id: 1300347:I601_RS07690
uniprot id: A0A1A9GIS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1300347:I601 RS08470
gene id: 1300347:I601_RS08470
uniprot id: A0A1A9GKG1
names: Similarity
messages: Belongs to the PhoU family.
messages: Belongs to the UPF0111 family.

1300347:I601 RS12775
gene id: 1300347:I601_RS12775
uniprot id: A0A1A9GN24
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1300347:I601 RS05410
gene id: 1300347:I601_RS05410
uniprot id: A0A1A9GH26
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1300347:I601 RS10635
gene id: 1300347:I601_RS10635
uniprot id: A0A1A9GLN9
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS10190
gene id: 1300347:I601_RS10190
uniprot id: A0A1A9GM15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1300347:I601 RS11995
gene id: 1300347:I601_RS11995
uniprot id: A0A1A9GKN1
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS03295
gene id: 1300347:I601_RS03295
uniprot id: A0A1A9GGD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1300347:I601 RS02210
gene id: 1300347:I601_RS02210
uniprot id: A0A1A9GGY4
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1300347:I601 RS02275
gene id: 1300347:I601_RS02275
uniprot id: A0A1A9GHG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1300347:I601 RS07240
gene id: 1300347:I601_RS07240
uniprot id: A0A1A9GHU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1300347:I601 RS02320
gene id: 1300347:I601_RS02320
uniprot id: A0A1A9GF92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1300347:I601 RS17075
gene id: 1300347:I601_RS17075
uniprot id: A0A1A9GNI7
names: Similarity
messages: Belongs to the peptidase S8 family.

1300347:I601 RS14975
gene id: 1300347:I601_RS14975
uniprot id: A0A1A9GPR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1300347:I601 RS20220
gene id: 1300347:I601_RS20220
uniprot id: A0A1A9GSS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1300347:I601 RS12875
gene id: 1300347:I601_RS12875
uniprot id: A0A1A9GN46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1300347:I601 RS07260
gene id: 1300347:I601_RS07260
uniprot id: A0A1A9GJW4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

1300347:I601 RS06610
gene id: 1300347:I601_RS06610
uniprot id: A0A1A9GHQ3
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1300347:I601 RS09970
gene id: 1300347:I601_RS09970
uniprot id: A0A1A9GL90
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1300347:I601 RS08100
gene id: 1300347:I601_RS08100
uniprot id: A0A1A9GIC9
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

1300347:I601 RS01985
gene id: 1300347:I601_RS01985
uniprot id: A0A1A9GEZ0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1300347:I601 RS18690
gene id: 1300347:I601_RS18690
uniprot id: A0A1A9GRS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1300347:I601 RS03070
gene id: 1300347:I601_RS03070
uniprot id: A0A1A9GFP9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1300347:I601 RS11475
gene id: 1300347:I601_RS11475
uniprot id: A0A1A9GKC7
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS16040
gene id: 1300347:I601_RS16040
uniprot id: A0A1A9GMY5
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS18145
gene id: 1300347:I601_RS18145
uniprot id: A0A1A9GR31
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1300347:I601 RS13865
gene id: 1300347:I601_RS13865
uniprot id: A0A1A9GLR9
names: Similarity
messages: Belongs to the CdaR family.

1300347:I601 RS21100
gene id: 1300347:I601_RS21100
uniprot id: A0A1A9GIX0
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1300347:I601 RS11585
gene id: 1300347:I601_RS11585
uniprot id: A0A1A9GKE5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1300347:I601 RS17850
gene id: 1300347:I601_RS17850
uniprot id: A0A1A9GRA6
names: Similarity
messages: Belongs to the AHA1 family.

1300347:I601 RS19355
gene id: 1300347:I601_RS19355
uniprot id: A0A1A9GPT4
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS08340
gene id: 1300347:I601_RS08340
uniprot id: A0A1A9GJ68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate, the first step in the de novo biosynthesis of NAD(+).
messages: Cytoplasm

1300347:I601 RS10955
gene id: 1300347:I601_RS10955
uniprot id: A0A1A9GJX9
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS07695
gene id: 1300347:I601_RS07695
uniprot id: A0A1A9GI51
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300347:I601 RS19170
gene id: 1300347:I601_RS19170
uniprot id: A0A1A9GRM5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1300347:I601 RS07220
gene id: 1300347:I601_RS07220
uniprot id: A0A1A9GKB3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1300347:I601 RS04700
gene id: 1300347:I601_RS04700
uniprot id: A0A1A9GIA6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1300347:I601 RS17015
gene id: 1300347:I601_RS17015
uniprot id: A0A1A9GQC3
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

1300347:I601 RS08230
gene id: 1300347:I601_RS08230
uniprot id: A0A1A9GIM7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1300347:I601 RS16640
gene id: 1300347:I601_RS16640
uniprot id: A0A1A9GNV1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1300347:I601 RS13885
gene id: 1300347:I601_RS13885
uniprot id: A0A1A9GNJ0
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1300347:I601 RS18755
gene id: 1300347:I601_RS18755
uniprot id: A0A1A9GPH9
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS02745
gene id: 1300347:I601_RS02745
uniprot id: A0A1A9GF87
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

1300347:I601 RS09095
gene id: 1300347:I601_RS09095
uniprot id: A0A1A9GIY5
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1300347:I601 RS02640
gene id: 1300347:I601_RS02640
uniprot id: A0A1A9GFD6
names: Similarity
messages: Belongs to the group II decarboxylase family.

1300347:I601 RS06360
gene id: 1300347:I601_RS06360
uniprot id: A0A1A9GJT0
names: Similarity
messages: Belongs to the FBPase class 2 family.

1300347:I601 RS03695
gene id: 1300347:I601_RS03695
uniprot id: A0A1A9GG33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1300347:I601 RS07725
gene id: 1300347:I601_RS07725
uniprot id: A0A1A9GK71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1300347:I601 RS17405
gene id: 1300347:I601_RS17405
uniprot id: A0A1A9GQH9
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1300347:I601 RS12295
gene id: 1300347:I601_RS12295
uniprot id: A0A1A9GKN6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1300347:I601 RS08535
gene id: 1300347:I601_RS08535
uniprot id: A0A1A9GL38
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1300347:I601 RS21720
gene id: 1300347:I601_RS21720
uniprot id: A0A1A9GLL3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1300347:I601 RS16965
gene id: 1300347:I601_RS16965
uniprot id: A0A1A9GQB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1300347:I601 RS09920
gene id: 1300347:I601_RS09920
uniprot id: A0A1A9GL81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1300347:I601 RS09045
gene id: 1300347:I601_RS09045
uniprot id: A0A1A9GIX6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1300347:I601 RS18885
gene id: 1300347:I601_RS18885
uniprot id: A0A1A9GRT7
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS06155
gene id: 1300347:I601_RS06155
uniprot id: A0A1A9GHG2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1300347:I601 RS02895
gene id: 1300347:I601_RS02895
uniprot id: A0A1A9GFC9
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

1300347:I601 RS17225
gene id: 1300347:I601_RS17225
uniprot id: A0A1A9GNL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1300347:I601 RS07655
gene id: 1300347:I601_RS07655
uniprot id: A0A1A9GI24
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1300347:I601 RS11820
gene id: 1300347:I601_RS11820
uniprot id: A0A1A9GMH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1300347:I601 RS02230
gene id: 1300347:I601_RS02230
uniprot id: A0A1A9GFS1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1300347:I601 RS03875
gene id: 1300347:I601_RS03875
uniprot id: A0A1A9GG12
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.

1300347:I601 RS13200
gene id: 1300347:I601_RS13200
uniprot id: A0A1A9GLD0
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS14945
gene id: 1300347:I601_RS14945
uniprot id: A0A1A9GMB0
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

1300347:I601 RS00385
gene id: 1300347:I601_RS00385
uniprot id: A0A1A9GE33
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1300347:I601 RS03865
gene id: 1300347:I601_RS03865
uniprot id: A0A1A9GIF3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1300347:I601 RS15710
gene id: 1300347:I601_RS15710
uniprot id: A0A1A9GMR6
names: Similarity
messages: Belongs to the cytochrome P450 family.

1300347:I601 RS04025
gene id: 1300347:I601_RS04025
uniprot id: A0A1A9GG40
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1300347:I601 RS15065
gene id: 1300347:I601_RS15065
uniprot id: A0A1A9GPC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1300347:I601 RS01210
gene id: 1300347:I601_RS01210
uniprot id: A0A1A9GGP5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1300347:I601 RS08735
gene id: 1300347:I601_RS08735
uniprot id: A0A1A9GIZ5
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

1300347:I601 RS09545
gene id: 1300347:I601_RS09545
uniprot id: A0A1A9GJ64
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS03955
gene id: 1300347:I601_RS03955
uniprot id: A0A1A9GHX6
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS02725
gene id: 1300347:I601_RS02725
uniprot id: A0A1A9GHQ9
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS04510
gene id: 1300347:I601_RS04510
uniprot id: A0A1A9GGJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1300347:I601 RS17570
gene id: 1300347:I601_RS17570
uniprot id: A0A1A9GQS0
names: Similarity
messages: Belongs to the UPF0047 family.

1300347:I601 RS11260
gene id: 1300347:I601_RS11260
uniprot id: A0A1A9GKT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1300347:I601 RS02325
gene id: 1300347:I601_RS02325
uniprot id: A0A1A9GHH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1300347:I601 RS02760
gene id: 1300347:I601_RS02760
uniprot id: A0A1A9GH96
names: Similarity
messages: Belongs to the universal stress protein A family.

1300347:I601 RS09720
gene id: 1300347:I601_RS09720
uniprot id: A0A1A9GLP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1300347:I601 RS09335
gene id: 1300347:I601_RS09335
uniprot id: A0A1A9GLJ0
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

1300347:I601 RS13505
gene id: 1300347:I601_RS13505
uniprot id: A0A1A9GLH6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300347:I601 RS02935
gene id: 1300347:I601_RS02935
uniprot id: A0A1A9GFH7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1300347:I601 RS12715
gene id: 1300347:I601_RS12715
uniprot id: A0A1A9GNC7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1300347:I601 RS09040
gene id: 1300347:I601_RS09040
uniprot id: A0A1A9GJM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

1300347:I601 RS05700
gene id: 1300347:I601_RS05700
uniprot id: A0A1A9GIU6
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1300347:I601 RS20350
gene id: 1300347:I601_RS20350
uniprot id: A0A1A9GQD0
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS10710
gene id: 1300347:I601_RS10710
uniprot id: A0A1A9GJT2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1300347:I601 RS02750
gene id: 1300347:I601_RS02750
uniprot id: A0A1A9GH54
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.

1300347:I601 RS12450
gene id: 1300347:I601_RS12450
uniprot id: A0A1A9GKR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1300347:I601 RS14520
gene id: 1300347:I601_RS14520
uniprot id: A0A1A9GM39
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1300347:I601 RS17525
gene id: 1300347:I601_RS17525
uniprot id: A0A1A9GNS3
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1300347:I601 RS06900
gene id: 1300347:I601_RS06900
uniprot id: A0A1A9GJP7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

1300347:I601 RS20125
gene id: 1300347:I601_RS20125
uniprot id: A0A1A9GS41
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Membrane

1300347:I601 RS06880
gene id: 1300347:I601_RS06880
uniprot id: A0A1A9GHM7
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS18925
gene id: 1300347:I601_RS18925
uniprot id: A0A1A9GRG2
names: Similarity
messages: Belongs to the glutamate synthase family.

1300347:I601 RS19975
gene id: 1300347:I601_RS19975
uniprot id: A0A1A9GS65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1300347:I601 RS02270
gene id: 1300347:I601_RS02270
uniprot id: A0A1A9GF84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1300347:I601 RS18850
gene id: 1300347:I601_RS18850
uniprot id: A0A1A9GPJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1300347:I601 RS07930
gene id: 1300347:I601_RS07930
uniprot id: A0A1A9GK45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1300347:I601 RS03270
gene id: 1300347:I601_RS03270
uniprot id: A0A1A9GHJ5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1300347:I601 RS01315
gene id: 1300347:I601_RS01315
uniprot id: A0A1A9GGF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1300347:I601 RS18180
gene id: 1300347:I601_RS18180
uniprot id: A0A1A9GQZ1
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS15995
gene id: 1300347:I601_RS15995
uniprot id: A0A1A9GPW0
names: Similarity
messages: Belongs to the universal stress protein A family.

1300347:I601 RS10345
gene id: 1300347:I601_RS10345
uniprot id: A0A1A9GKB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1300347:I601 RS15655
gene id: 1300347:I601_RS15655
uniprot id: A0A1A9GPN5
names: Similarity
messages: Belongs to the cytochrome P450 family.

1300347:I601 RS19055
gene id: 1300347:I601_RS19055
uniprot id: A0A1A9GPM3
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1300347:I601 RS18935
gene id: 1300347:I601_RS18935
uniprot id: A0A1A9GRU8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1300347:I601 RS15130
gene id: 1300347:I601_RS15130
uniprot id: A0A1A9GN10
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1300347:I601 RS01570
gene id: 1300347:I601_RS01570
uniprot id: A0A1A9GEV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1300347:I601 RS02370
gene id: 1300347:I601_RS02370
uniprot id: A0A1A9GFA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1300347:I601 RS10645
gene id: 1300347:I601_RS10645
uniprot id: A0A1A9GJZ8
names: Similarity
messages: Belongs to the universal stress protein A family.

1300347:I601 RS05375
gene id: 1300347:I601_RS05375
uniprot id: A0A1A9GGV0
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1300347:I601 RS16425
gene id: 1300347:I601_RS16425
uniprot id: A0A1A9GN63
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily.

1300347:I601 RS15970
gene id: 1300347:I601_RS15970
uniprot id: A0A1A9GMV7
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS13385
gene id: 1300347:I601_RS13385
uniprot id: A0A1A9GNV5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1300347:I601 RS08725
gene id: 1300347:I601_RS08725
uniprot id: A0A1A9GL55
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1300347:I601 RS04005
gene id: 1300347:I601_RS04005
uniprot id: A0A1A9GI21
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1300347:I601 RS13780
gene id: 1300347:I601_RS13780
uniprot id: A0A1A9GP05
names: Function
names: Similarity
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

1300347:I601 RS11735
gene id: 1300347:I601_RS11735
uniprot id: A0A1A9GKI2
names: Similarity
messages: Belongs to the FPG family.

1300347:I601 RS06590
gene id: 1300347:I601_RS06590
uniprot id: A0A1A9GJB5
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1300347:I601 RS04450
gene id: 1300347:I601_RS04450
uniprot id: A0A1A9GI62
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1300347:I601 RS20120
gene id: 1300347:I601_RS20120
uniprot id: A0A1A9GSA0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1300347:I601 RS11975
gene id: 1300347:I601_RS11975
uniprot id: A0A1A9GKP6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1300347:I601 RS06140
gene id: 1300347:I601_RS06140
uniprot id: A0A1A9GJK5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1300347:I601 RS18605
gene id: 1300347:I601_RS18605
uniprot id: A0A1A9GPE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1300347:I601 RS02105
gene id: 1300347:I601_RS02105
uniprot id: A0A1A9GH75
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1300347:I601 RS11730
gene id: 1300347:I601_RS11730
uniprot id: A0A1A9GKC5
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1300347:I601 RS19250
gene id: 1300347:I601_RS19250
uniprot id: A0A1A9GPS5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1300347:I601 RS17965
gene id: 1300347:I601_RS17965
uniprot id: A0A1A9GP08
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS13325
gene id: 1300347:I601_RS13325
uniprot id: A0A1A9GND8
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

1300347:I601 RS05980
gene id: 1300347:I601_RS05980
uniprot id: A0A1A9GH59
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

1300347:I601 RS12065
gene id: 1300347:I601_RS12065
uniprot id: A0A1A9GMF9
names: Similarity
messages: Belongs to the peptidase S66 family.

1300347:I601 RS08300
gene id: 1300347:I601_RS08300
uniprot id: A0A1A9GIL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1300347:I601 RS06530
gene id: 1300347:I601_RS06530
uniprot id: A0A1A9GHJ0
names: Similarity
messages: Belongs to the carbamate kinase family.

1300347:I601 RS14795
gene id: 1300347:I601_RS14795
uniprot id: A0A1A9GM76
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1300347:I601 RS08770
gene id: 1300347:I601_RS08770
uniprot id: A0A1A9GL68
names: Caution
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300347:I601 RS19970
gene id: 1300347:I601_RS19970
uniprot id: A0A1A9GSK1
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS17150
gene id: 1300347:I601_RS17150
uniprot id: A0A1A9GNI3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1300347:I601 RS07615
gene id: 1300347:I601_RS07615
uniprot id: A0A1A9GJW7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1300347:I601 RS18205
gene id: 1300347:I601_RS18205
uniprot id: A0A1A9GP54
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

1300347:I601 RS08640
gene id: 1300347:I601_RS08640
uniprot id: A0A1A9GIP9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1300347:I601 RS04205
gene id: 1300347:I601_RS04205
uniprot id: A0A1A9GGD5
names: Similarity
messages: Belongs to the pirin family.

1300347:I601 RS13210
gene id: 1300347:I601_RS13210
uniprot id: A0A1A9GN51
names: Similarity
messages: Belongs to the GSP E family.

1300347:I601 RS17670
gene id: 1300347:I601_RS17670
uniprot id: A0A1A9GR85
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

1300347:I601 RS19050
gene id: 1300347:I601_RS19050
uniprot id: A0A1A9GPN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1300347:I601 RS02535
gene id: 1300347:I601_RS02535
uniprot id: A0A1A9GF96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1300347:I601 RS16045
gene id: 1300347:I601_RS16045
uniprot id: A0A1A9GQC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1300347:I601 RS01955
gene id: 1300347:I601_RS01955
uniprot id: A0A1A9GH43
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1300347:I601 RS19425
gene id: 1300347:I601_RS19425
uniprot id: A0A1A9GRR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1300347:I601 RS09240
gene id: 1300347:I601_RS09240
uniprot id: A0A1A9GLH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1300347:I601 RS19665
gene id: 1300347:I601_RS19665
uniprot id: A0A1A9GSF9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1300347:I601 RS04585
gene id: 1300347:I601_RS04585
uniprot id: A0A1A9GGB4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300347:I601 RS17000
gene id: 1300347:I601_RS17000
uniprot id: A0A1A9GNF5
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1300347:I601 RS17030
gene id: 1300347:I601_RS17030
uniprot id: A0A1A9GQX4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1300347:I601 RS01265
gene id: 1300347:I601_RS01265
uniprot id: A0A1A9GGE4
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS07665
gene id: 1300347:I601_RS07665
uniprot id: A0A1A9GKH5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1300347:I601 RS18240
gene id: 1300347:I601_RS18240
uniprot id: A0A1A9GRK2
names: Similarity
messages: Belongs to the TrpC family.

1300347:I601 RS16980
gene id: 1300347:I601_RS16980
uniprot id: A0A1A9GQW3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

1300347:I601 RS09790
gene id: 1300347:I601_RS09790
uniprot id: A0A1A9GLT7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1300347:I601 RS11070
gene id: 1300347:I601_RS11070
uniprot id: A0A1A9GK55
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS07350
gene id: 1300347:I601_RS07350
uniprot id: A0A1A9GKA6
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1300347:I601 RS02140
gene id: 1300347:I601_RS02140
uniprot id: A0A1A9GF41
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS20500
gene id: 1300347:I601_RS20500
uniprot id: A0A1A9GSY4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1300347:I601 RS09980
gene id: 1300347:I601_RS09980
uniprot id: A0A1A9GLB8
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

1300347:I601 RS16970
gene id: 1300347:I601_RS16970
uniprot id: A0A1A9GQG0
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1300347:I601 RS19135
gene id: 1300347:I601_RS19135
uniprot id: A0A1A9GRZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1300347:I601 RS12115
gene id: 1300347:I601_RS12115
uniprot id: A0A1A9GMG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

1300347:I601 RS04535
gene id: 1300347:I601_RS04535
uniprot id: A0A1A9GGA1
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1300347:I601 RS14930
gene id: 1300347:I601_RS14930
uniprot id: A0A1A9GMX2
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1300347:I601 RS07680
gene id: 1300347:I601_RS07680
uniprot id: A0A1A9GIB8
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS01525
gene id: 1300347:I601_RS01525
uniprot id: A0A1A9GH01
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1300347:I601 RS06240
gene id: 1300347:I601_RS06240
uniprot id: A0A1A9GJ58
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1300347:I601 RS16915
gene id: 1300347:I601_RS16915
uniprot id: A0A1A9GQA3
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1300347:I601 RS14860
gene id: 1300347:I601_RS14860
uniprot id: A0A1A9GP26
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1300347:I601 RS02250
gene id: 1300347:I601_RS02250
uniprot id: A0A1A9GGV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1300347:I601 RS10195
gene id: 1300347:I601_RS10195
uniprot id: A0A1A9GK85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1300347:I601 RS03300
gene id: 1300347:I601_RS03300
uniprot id: A0A1A9GFQ0
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1300347:I601 RS04085
gene id: 1300347:I601_RS04085
uniprot id: A0A1A9GHX2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1300347:I601 RS17560
gene id: 1300347:I601_RS17560
uniprot id: A0A1A9GR48
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1300347:I601 RS11520
gene id: 1300347:I601_RS11520
uniprot id: A0A1A9GKE4
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS17890
gene id: 1300347:I601_RS17890
uniprot id: A0A1A9GNY4
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

1300347:I601 RS16275
gene id: 1300347:I601_RS16275
uniprot id: A0A1A9GQ20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1300347:I601 RS20365
gene id: 1300347:I601_RS20365
uniprot id: A0A1A9GSE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1300347:I601 RS10780
gene id: 1300347:I601_RS10780
uniprot id: A0A1A9GLS0
names: Similarity
messages: Belongs to the peptidase S1C family.

1300347:I601 RS02305
gene id: 1300347:I601_RS02305
uniprot id: A0A1A9GHC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1300347:I601 RS18655
gene id: 1300347:I601_RS18655
uniprot id: A0A1A9GPG0
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1300347:I601 RS10215
gene id: 1300347:I601_RS10215
uniprot id: A0A1A9GLD9
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1300347:I601 RS05150
gene id: 1300347:I601_RS05150
uniprot id: A0A1A9GIJ3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1300347:I601 RS17145
gene id: 1300347:I601_RS17145
uniprot id: A0A1A9GNJ9
names: Similarity
messages: Belongs to the cytochrome P450 family.

1300347:I601 RS00130
gene id: 1300347:I601_RS00130
uniprot id: A0A1A9GFU2
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS16105
gene id: 1300347:I601_RS16105
uniprot id: A0A1A9GMW3
names: Similarity
messages: Belongs to the peptidase U62 family.

1300347:I601 RS14745
gene id: 1300347:I601_RS14745
uniprot id: A0A1A9GM67
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Homodimer.

1300347:I601 RS18500
gene id: 1300347:I601_RS18500
uniprot id: A0A1A9GPA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1300347:I601 RS18560
gene id: 1300347:I601_RS18560
uniprot id: A0A1A9GPB5
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS14350
gene id: 1300347:I601_RS14350
uniprot id: A0A1A9GPE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1300347:I601 RS17535
gene id: 1300347:I601_RS17535
uniprot id: A0A1A9GPD6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1300347:I601 RS11650
gene id: 1300347:I601_RS11650
uniprot id: A0A1A9GMR8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1300347:I601 RS19390
gene id: 1300347:I601_RS19390
uniprot id: A0A1A9GQH2
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

1300347:I601 RS05865
gene id: 1300347:I601_RS05865
uniprot id: A0A1A9GJH9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1300347:I601 RS19740
gene id: 1300347:I601_RS19740
uniprot id: A0A1A9GQM4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

1300347:I601 RS08465
gene id: 1300347:I601_RS08465
uniprot id: A0A1A9GKZ2
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS12950
gene id: 1300347:I601_RS12950
uniprot id: A0A1A9GL75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1300347:I601 RS03665
gene id: 1300347:I601_RS03665
uniprot id: A0A1A9GFT8
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1300347:I601 RS13625
gene id: 1300347:I601_RS13625
uniprot id: A0A1A9GNX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1300347:I601 RS17640
gene id: 1300347:I601_RS17640
uniprot id: A0A1A9GNU8
names: Similarity
messages: Belongs to the UPF0045 family.

1300347:I601 RS13470
gene id: 1300347:I601_RS13470
uniprot id: A0A1A9GNB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1300347:I601 RS09155
gene id: 1300347:I601_RS09155
uniprot id: A0A1A9GJ01
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1300347:I601 RS07805
gene id: 1300347:I601_RS07805
uniprot id: A0A1A9GI60
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

1300347:I601 RS05735
gene id: 1300347:I601_RS05735
uniprot id: A0A1A9GGZ9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1300347:I601 RS05325
gene id: 1300347:I601_RS05325
uniprot id: A0A1A9GGU1
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1300347:I601 RS03305
gene id: 1300347:I601_RS03305
uniprot id: A0A1A9GFR6
names: Similarity
messages: Belongs to the UDPGP type 1 family.

1300347:I601 RS09125
gene id: 1300347:I601_RS09125
uniprot id: A0A1A9GL11
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300347:I601 RS06745
gene id: 1300347:I601_RS06745
uniprot id: A0A1A9GJF6
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1300347:I601 RS08690
gene id: 1300347:I601_RS08690
uniprot id: A0A1A9GIQ9
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1300347:I601 RS08335
gene id: 1300347:I601_RS08335
uniprot id: A0A1A9GKY7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1300347:I601 RS07360
gene id: 1300347:I601_RS07360
uniprot id: A0A1A9GJY7
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1300347:I601 RS12350
gene id: 1300347:I601_RS12350
uniprot id: A0A1A9GKP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1300347:I601 RS17875
gene id: 1300347:I601_RS17875
uniprot id: A0A1A9GPK8
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

1300347:I601 RS07035
gene id: 1300347:I601_RS07035
uniprot id: A0A1A9GHU6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1300347:I601 RS12540
gene id: 1300347:I601_RS12540
uniprot id: A0A1A9GND0
names: Similarity
messages: Belongs to the UPF0102 family.

1300347:I601 RS14385
gene id: 1300347:I601_RS14385
uniprot id: A0A1A9GNT7
names: Similarity
messages: Belongs to the FPG family.

1300347:I601 RS15640
gene id: 1300347:I601_RS15640
uniprot id: A0A1A9GPH3
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1300347:I601 RS12790
gene id: 1300347:I601_RS12790
uniprot id: A0A1A9GLN3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1300347:I601 RS12570
gene id: 1300347:I601_RS12570
uniprot id: A0A1A9GMR5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300347:I601 RS15110
gene id: 1300347:I601_RS15110
uniprot id: A0A1A9GP72
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1300347:I601 RS11770
gene id: 1300347:I601_RS11770
uniprot id: A0A1A9GMG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1300347:I601 RS03650
gene id: 1300347:I601_RS03650
uniprot id: A0A1A9GGK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1300347:I601 RS19525
gene id: 1300347:I601_RS19525
uniprot id: A0A1A9GRS7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1300347:I601 RS04595
gene id: 1300347:I601_RS04595
uniprot id: A0A1A9GIN8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1300347:I601 RS08260
gene id: 1300347:I601_RS08260
uniprot id: A0A1A9GK95
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1300347:I601 RS10590
gene id: 1300347:I601_RS10590
uniprot id: A0A1A9GLU6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MshB deacetylase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.

1300347:I601 RS12100
gene id: 1300347:I601_RS12100
uniprot id: A0A1A9GKP0
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS16795
gene id: 1300347:I601_RS16795
uniprot id: A0A1A9GNA0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1300347:I601 RS05370
gene id: 1300347:I601_RS05370
uniprot id: A0A1A9GHI3
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS10085
gene id: 1300347:I601_RS10085
uniprot id: A0A1A9GLJ8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1300347:I601 RS03750
gene id: 1300347:I601_RS03750
uniprot id: A0A1A9GHX4
names: Similarity
messages: Belongs to the pirin family.

1300347:I601 RS02930
gene id: 1300347:I601_RS02930
uniprot id: A0A1A9GG65
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1300347:I601 RS19175
gene id: 1300347:I601_RS19175
uniprot id: A0A1A9GRL0
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1300347:I601 RS12625
gene id: 1300347:I601_RS12625
uniprot id: A0A1A9GMZ6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1300347:I601 RS04240
gene id: 1300347:I601_RS04240
uniprot id: A0A1A9GI25
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1300347:I601 RS03520
gene id: 1300347:I601_RS03520
uniprot id: A0A1A9GHM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.
messages: Mitochondrion

1300347:I601 RS11915
gene id: 1300347:I601_RS11915
uniprot id: A0A1A9GMD7
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

1300347:I601 RS07335
gene id: 1300347:I601_RS07335
uniprot id: A0A1A9GI07
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1300347:I601 RS15045
gene id: 1300347:I601_RS15045
uniprot id: A0A1A9GME2
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1300347:I601 RS09300
gene id: 1300347:I601_RS09300
uniprot id: A0A1A9GJ26
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1300347:I601 RS19360
gene id: 1300347:I601_RS19360
uniprot id: A0A1A9GRM6
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS04675
gene id: 1300347:I601_RS04675
uniprot id: A0A1A9GGG4
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1300347:I601 RS12720
gene id: 1300347:I601_RS12720
uniprot id: A0A1A9GMU8
names: Similarity
messages: Belongs to the DDAH family.

1300347:I601 RS03860
gene id: 1300347:I601_RS03860
uniprot id: A0A1A9GG66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1300347:I601 RS13125
gene id: 1300347:I601_RS13125
uniprot id: A0A1A9GN99
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1300347:I601 RS13360
gene id: 1300347:I601_RS13360
uniprot id: A0A1A9GN81
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1300347:I601 RS12565
gene id: 1300347:I601_RS12565
uniprot id: A0A1A9GN94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1300347:I601 RS04930
gene id: 1300347:I601_RS04930
uniprot id: A0A1A9GGI5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1300347:I601 RS04680
gene id: 1300347:I601_RS04680
uniprot id: A0A1A9GGI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1300347:I601 RS16960
gene id: 1300347:I601_RS16960
uniprot id: A0A1A9GQT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1300347:I601 RS11390
gene id: 1300347:I601_RS11390
uniprot id: A0A1A9GMA7
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1300347:I601 RS03210
gene id: 1300347:I601_RS03210
uniprot id: A0A1A9GHE7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1300347:I601 RS00920
gene id: 1300347:I601_RS00920
uniprot id: A0A1A9GG97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1300347:I601 RS14525
gene id: 1300347:I601_RS14525
uniprot id: A0A1A9GM33
names: Subcellular Location Annotation
messages: Membrane

1300347:I601 RS01155
gene id: 1300347:I601_RS01155
uniprot id: A0A1A9GG70
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300347:I601 RS19670
gene id: 1300347:I601_RS19670
uniprot id: A0A1A9GRZ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.