1300344:I598 RS06890
gene id: 1300344:I598_RS06890
uniprot id: A0A168F650
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

1300344:I598 RS03880
gene id: 1300344:I598_RS03880
uniprot id: A0A168EQS7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1300344:I598 RS15255
gene id: 1300344:I598_RS15255
uniprot id: A0A161IKA9
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

1300344:I598 RS03510
gene id: 1300344:I598_RS03510
uniprot id: A0A168ENU2
names: Similarity
messages: Belongs to the Fur family.

1300344:I598 RS17085
gene id: 1300344:I598_RS17085
uniprot id: A0A161IH37
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1300344:I598 RS04280
gene id: 1300344:I598_RS04280
uniprot id: A0A168ESW8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1300344:I598 RS04120
gene id: 1300344:I598_RS04120
uniprot id: A0A168ES39
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1300344:I598 RS05965
gene id: 1300344:I598_RS05965
uniprot id: A0A168F144
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1300344:I598 RS16090
gene id: 1300344:I598_RS16090
uniprot id: A0A161IGN3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1300344:I598 RS00780
gene id: 1300344:I598_RS00780
uniprot id: A0A168E955
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1300344:I598 RS07100
gene id: 1300344:I598_RS07100
uniprot id: A0A168F7H0
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1300344:I598 RS01300
gene id: 1300344:I598_RS01300
uniprot id: A0A168EBX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1300344:I598 RS08510
gene id: 1300344:I598_RS08510
uniprot id: A0A161I6Y3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1300344:I598 RS05225
gene id: 1300344:I598_RS05225
uniprot id: A0A168EXP4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1300344:I598 RS00770
gene id: 1300344:I598_RS00770
uniprot id: A0A161I0Y4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1300344:I598 RS08965
gene id: 1300344:I598_RS08965
uniprot id: A0A161HQA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1300344:I598 RS11630
gene id: 1300344:I598_RS11630
uniprot id: A0A161I2I9
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1300344:I598 RS14985
gene id: 1300344:I598_RS14985
uniprot id: A0A168FUR1
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1300344:I598 RS16135
gene id: 1300344:I598_RS16135
uniprot id: A0A168FZ13
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

1300344:I598 RS13490
gene id: 1300344:I598_RS13490
uniprot id: A0A168FPI9
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1300344:I598 RS01880
gene id: 1300344:I598_RS01880
uniprot id: A0A168EFE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

1300344:I598 RS08550
gene id: 1300344:I598_RS08550
uniprot id: A0A168FBE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1300344:I598 RS15170
gene id: 1300344:I598_RS15170
uniprot id: A0A161IG76
names: Subcellular Location Annotation
messages: Cytoplasm

1300344:I598 RS07610
gene id: 1300344:I598_RS07610
uniprot id: A0A168F930
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1300344:I598 RS14730
gene id: 1300344:I598_RS14730
uniprot id: A0A168FTT8
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1300344:I598 RS00015
gene id: 1300344:I598_RS00015
uniprot id: A0A168E4B7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1300344:I598 RS03645
gene id: 1300344:I598_RS03645
uniprot id: A0A168EPH1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1300344:I598 RS09160
gene id: 1300344:I598_RS09160
uniprot id: A0A168FCX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1300344:I598 RS06455
gene id: 1300344:I598_RS06455
uniprot id: A0A161I120
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1300344:I598 RS08545
gene id: 1300344:I598_RS08545
uniprot id: A0A161I1P8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1300344:I598 RS12515
gene id: 1300344:I598_RS12515
uniprot id: A0A161I8J6
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS15380
gene id: 1300344:I598_RS15380
uniprot id: A0A168FWE9
names: Similarity
messages: Belongs to the peptidase C40 family.

1300344:I598 RS03440
gene id: 1300344:I598_RS03440
uniprot id: A0A161HZS1
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1300344:I598 RS00445
gene id: 1300344:I598_RS00445
uniprot id: A0A168E7B9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1300344:I598 RS05630
gene id: 1300344:I598_RS05630
uniprot id: A0A168EZH5
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1300344:I598 RS03550
gene id: 1300344:I598_RS03550
uniprot id: A0A168ENY6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1300344:I598 RS05425
gene id: 1300344:I598_RS05425
uniprot id: A0A161I0M0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1300344:I598 RS15090
gene id: 1300344:I598_RS15090
uniprot id: A0A161HSN5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300344:I598 RS15595
gene id: 1300344:I598_RS15595
uniprot id: A0A168FX77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1300344:I598 RS11220
gene id: 1300344:I598_RS11220
uniprot id: A0A161HRA5
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1300344:I598 RS03390
gene id: 1300344:I598_RS03390
uniprot id: A0A168EN83
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1300344:I598 RS01035
gene id: 1300344:I598_RS01035
uniprot id: A0A161IIB9
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS03445
gene id: 1300344:I598_RS03445
uniprot id: A0A168ENH5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1300344:I598 RS08190
gene id: 1300344:I598_RS08190
uniprot id: A0A161I6T6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1300344:I598 RS10425
gene id: 1300344:I598_RS10425
uniprot id: A0A161I290
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300344:I598 RS17090
gene id: 1300344:I598_RS17090
uniprot id: A0A161IA58
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1300344:I598 RS06280
gene id: 1300344:I598_RS06280
uniprot id: A0A161IKG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1300344:I598 RS05055
gene id: 1300344:I598_RS05055
uniprot id: A0A168EWX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1300344:I598 RS07150
gene id: 1300344:I598_RS07150
uniprot id: A0A168F7R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1300344:I598 RS11015
gene id: 1300344:I598_RS11015
uniprot id: A0A168FHA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1300344:I598 RS06520
gene id: 1300344:I598_RS06520
uniprot id: A0A168F3Y5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1300344:I598 RS12190
gene id: 1300344:I598_RS12190
uniprot id: A0A161IJ44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1300344:I598 RS03615
gene id: 1300344:I598_RS03615
uniprot id: A0A161IJE3
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300344:I598 RS16930
gene id: 1300344:I598_RS16930
uniprot id: A0A168G1U6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1300344:I598 RS00080
gene id: 1300344:I598_RS00080
uniprot id: A0A168E4Q4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300344:I598 RS15705
gene id: 1300344:I598_RS15705
uniprot id: A0A168FXI9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

1300344:I598 RS06705
gene id: 1300344:I598_RS06705
uniprot id: A0A161I155
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

1300344:I598 RS08225
gene id: 1300344:I598_RS08225
uniprot id: A0A161I1L7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1300344:I598 RS16920
gene id: 1300344:I598_RS16920
uniprot id: A0A161IKZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1300344:I598 RS10265
gene id: 1300344:I598_RS10265
uniprot id: A0A161HQW8
names: Similarity
messages: Belongs to the GARS family.

1300344:I598 RS08230
gene id: 1300344:I598_RS08230
uniprot id: A0A168FAQ7
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1300344:I598 RS15735
gene id: 1300344:I598_RS15735
uniprot id: A0A161I9M2
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1300344:I598 RS12550
gene id: 1300344:I598_RS12550
uniprot id: A0A161I2T1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1300344:I598 RS01385
gene id: 1300344:I598_RS01385
uniprot id: A0A161IIH4
names: Similarity
messages: Belongs to the Dps family.

1300344:I598 RS05165
gene id: 1300344:I598_RS05165
uniprot id: A0A161IGC2
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS14490
gene id: 1300344:I598_RS14490
uniprot id: A0A161HSH4
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

1300344:I598 RS09645
gene id: 1300344:I598_RS09645
uniprot id: A0A161HQM0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1300344:I598 RS03605
gene id: 1300344:I598_RS03605
uniprot id: A0A168EPB5
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

1300344:I598 RS06945
gene id: 1300344:I598_RS06945
uniprot id: A0A168F6K3
names: Cofactor
messages: Can also use Mn(2+) ion.

1300344:I598 RS16200
gene id: 1300344:I598_RS16200
uniprot id: A0A168FZD5
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

1300344:I598 RS12555
gene id: 1300344:I598_RS12555
uniprot id: A0A168FL97
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1300344:I598 RS04260
gene id: 1300344:I598_RS04260
uniprot id: A0A168ESR1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1300344:I598 RS05180
gene id: 1300344:I598_RS05180
uniprot id: A0A168EXI6
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS07810
gene id: 1300344:I598_RS07810
uniprot id: A0A161HPW8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1300344:I598 RS05260
gene id: 1300344:I598_RS05260
uniprot id: A0A168EXW1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1300344:I598 RS09865
gene id: 1300344:I598_RS09865
uniprot id: A0A161IE14
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS00245
gene id: 1300344:I598_RS00245
uniprot id: A0A168E5S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1300344:I598 RS05880
gene id: 1300344:I598_RS05880
uniprot id: A0A161IGN8
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300344:I598 RS13630
gene id: 1300344:I598_RS13630
uniprot id: A0A161I8Y6
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1300344:I598 RS10010
gene id: 1300344:I598_RS10010
uniprot id: A0A161HQT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1300344:I598 RS05545
gene id: 1300344:I598_RS05545
uniprot id: A0A168EZ65
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS03875
gene id: 1300344:I598_RS03875
uniprot id: A0A168EQR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

1300344:I598 RS10980
gene id: 1300344:I598_RS10980
uniprot id: A0A161IIL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1300344:I598 RS07985
gene id: 1300344:I598_RS07985
uniprot id: A0A161ID61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1300344:I598 RS11055
gene id: 1300344:I598_RS11055
uniprot id: A0A168FHD4
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1300344:I598 RS15730
gene id: 1300344:I598_RS15730
uniprot id: A0A161IGH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1300344:I598 RS10755
gene id: 1300344:I598_RS10755
uniprot id: A0A161IM81
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1300344:I598 RS13650
gene id: 1300344:I598_RS13650
uniprot id: A0A161HS90
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1300344:I598 RS13210
gene id: 1300344:I598_RS13210
uniprot id: A0A168FNG9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1300344:I598 RS07400
gene id: 1300344:I598_RS07400
uniprot id: A0A161I6H6
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1300344:I598 RS00850
gene id: 1300344:I598_RS00850
uniprot id: A0A161IEG9
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS08635
gene id: 1300344:I598_RS08635
uniprot id: A0A161I1Q5
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS10560
gene id: 1300344:I598_RS10560
uniprot id: A0A168FGC2
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS04820
gene id: 1300344:I598_RS04820
uniprot id: A0A168EVQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1300344:I598 RS12845
gene id: 1300344:I598_RS12845
uniprot id: A0A161I2W0
names: Subcellular Location Annotation
messages: Cytoplasm

1300344:I598 RS00440
gene id: 1300344:I598_RS00440
uniprot id: A0A168E7A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1300344:I598 RS04850
gene id: 1300344:I598_RS04850
uniprot id: A0A161HWH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1300344:I598 RS16035
gene id: 1300344:I598_RS16035
uniprot id: A0A168FYQ9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1300344:I598 RS08110
gene id: 1300344:I598_RS08110
uniprot id: A0A161HQ07
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1300344:I598 RS09155
gene id: 1300344:I598_RS09155
uniprot id: A0A161ILJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1300344:I598 RS05205
gene id: 1300344:I598_RS05205
uniprot id: A0A168EXM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1300344:I598 RS01935
gene id: 1300344:I598_RS01935
uniprot id: A0A168EFQ5
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1300344:I598 RS09135
gene id: 1300344:I598_RS09135
uniprot id: A0A168FCV2
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

1300344:I598 RS04710
gene id: 1300344:I598_RS04710
uniprot id: A0A161I099
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1300344:I598 RS01770
gene id: 1300344:I598_RS01770
uniprot id: A0A161IEY7
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1300344:I598 RS03795
gene id: 1300344:I598_RS03795
uniprot id: A0A161HZW2
names: Similarity
messages: Belongs to the TrpC family.

1300344:I598 RS08680
gene id: 1300344:I598_RS08680
uniprot id: A0A161I1R4
names: Similarity
messages: Belongs to the histone deacetylase family.

1300344:I598 RS01190
gene id: 1300344:I598_RS01190
uniprot id: A0A161I133
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1300344:I598 RS03320
gene id: 1300344:I598_RS03320
uniprot id: A0A168EMW5
names: Similarity
messages: Belongs to the UDPGP type 1 family.

1300344:I598 RS13590
gene id: 1300344:I598_RS13590
uniprot id: A0A168FPU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1300344:I598 RS00300
gene id: 1300344:I598_RS00300
uniprot id: A0A168E674
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300344:I598 RS08180
gene id: 1300344:I598_RS08180
uniprot id: A0A168FAJ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1300344:I598 RS03900
gene id: 1300344:I598_RS03900
uniprot id: A0A168EQV1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1300344:I598 RS12560
gene id: 1300344:I598_RS12560
uniprot id: A0A161IF82
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

1300344:I598 RS00660
gene id: 1300344:I598_RS00660
uniprot id: A0A168E8H1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1300344:I598 RS04620
gene id: 1300344:I598_RS04620
uniprot id: A0A168EUK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1300344:I598 RS03700
gene id: 1300344:I598_RS03700
uniprot id: A0A168EPT2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1300344:I598 RS08330
gene id: 1300344:I598_RS08330
uniprot id: A0A161I1M7
names: Similarity
messages: Belongs to the UPF0336 family.

1300344:I598 RS02680
gene id: 1300344:I598_RS02680
uniprot id: A0A161HVH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

1300344:I598 RS03840
gene id: 1300344:I598_RS03840
uniprot id: A0A161IFR2
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

1300344:I598 RS11100
gene id: 1300344:I598_RS11100
uniprot id: A0A161I7Y7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1300344:I598 RS12640
gene id: 1300344:I598_RS12640
uniprot id: A0A161HZM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1300344:I598 RS02925
gene id: 1300344:I598_RS02925
uniprot id: A0A168EL31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1300344:I598 RS02960
gene id: 1300344:I598_RS02960
uniprot id: A0A168EL98
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1300344:I598 RS05585
gene id: 1300344:I598_RS05585
uniprot id: A0A168EZA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1300344:I598 RS05250
gene id: 1300344:I598_RS05250
uniprot id: A0A161IK24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1300344:I598 RS17670
gene id: 1300344:I598_RS17670
uniprot id: A0A161IMX1
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

1300344:I598 RS14485
gene id: 1300344:I598_RS14485
uniprot id: A0A168FT13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1300344:I598 RS09600
gene id: 1300344:I598_RS09600
uniprot id: A0A161HYH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1300344:I598 RS01500
gene id: 1300344:I598_RS01500
uniprot id: A0A161IIJ1
names: Similarity
messages: Belongs to the universal stress protein A family.

1300344:I598 RS16980
gene id: 1300344:I598_RS16980
uniprot id: A0A168G1Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1300344:I598 RS03655
gene id: 1300344:I598_RS03655
uniprot id: A0A168EPK3
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1300344:I598 RS14315
gene id: 1300344:I598_RS14315
uniprot id: A0A168FSD3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1300344:I598 RS10810
gene id: 1300344:I598_RS10810
uniprot id: A0A168FGY3
names: Similarity
messages: Belongs to the TPP enzyme family.

1300344:I598 RS00680
gene id: 1300344:I598_RS00680
uniprot id: A0A168E8L3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1300344:I598 RS09310
gene id: 1300344:I598_RS09310
uniprot id: A0A168FDB0
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

1300344:I598 RS16285
gene id: 1300344:I598_RS16285
uniprot id: A0A161IGR1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1300344:I598 RS04595
gene id: 1300344:I598_RS04595
uniprot id: A0A168EUH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1300344:I598 RS05365
gene id: 1300344:I598_RS05365
uniprot id: A0A161HWQ9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1300344:I598 RS11445
gene id: 1300344:I598_RS11445
uniprot id: A0A161IEP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1300344:I598 RS12235
gene id: 1300344:I598_RS12235
uniprot id: A0A161HZG8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1300344:I598 RS02530
gene id: 1300344:I598_RS02530
uniprot id: A0A161HVE9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1300344:I598 RS06515
gene id: 1300344:I598_RS06515
uniprot id: A0A168F3W2
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS05570
gene id: 1300344:I598_RS05570
uniprot id: A0A161IGJ1
names: Similarity
messages: Belongs to the DDAH family.

1300344:I598 RS02875
gene id: 1300344:I598_RS02875
uniprot id: A0A168EKT8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1300344:I598 RS07165
gene id: 1300344:I598_RS07165
uniprot id: A0A161IH89
names: Similarity
messages: Belongs to the peptidase M24B family.

1300344:I598 RS15280
gene id: 1300344:I598_RS15280
uniprot id: A0A168FW08
names: Subcellular Location Annotation
messages: Cytoplasm

1300344:I598 RS04605
gene id: 1300344:I598_RS04605
uniprot id: A0A161IG30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1300344:I598 RS07995
gene id: 1300344:I598_RS07995
uniprot id: A0A168F9Z1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300344:I598 RS01520
gene id: 1300344:I598_RS01520
uniprot id: A0A161IEU0
names: Similarity
messages: Belongs to the universal stress protein A family.

1300344:I598 RS15225
gene id: 1300344:I598_RS15225
uniprot id: A0A161I9F8
names: Similarity
messages: Belongs to the PspA/IM30 family.

1300344:I598 RS05875
gene id: 1300344:I598_RS05875
uniprot id: A0A161HWZ3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1300344:I598 RS17245
gene id: 1300344:I598_RS17245
uniprot id: A0A168G2U6
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1300344:I598 RS01890
gene id: 1300344:I598_RS01890
uniprot id: A0A168EFH0
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS00590
gene id: 1300344:I598_RS00590
uniprot id: A0A168E845
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300344:I598 RS06765
gene id: 1300344:I598_RS06765
uniprot id: A0A168F5F3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1300344:I598 RS09175
gene id: 1300344:I598_RS09175
uniprot id: A0A161IHZ1
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1300344:I598 RS03010
gene id: 1300344:I598_RS03010
uniprot id: A0A168ELG5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300344:I598 RS08125
gene id: 1300344:I598_RS08125
uniprot id: A0A161I1K8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1300344:I598 RS07215
gene id: 1300344:I598_RS07215
uniprot id: A0A161IH98
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300344:I598 RS08020
gene id: 1300344:I598_RS08020
uniprot id: A0A161IHI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1300344:I598 RS11550
gene id: 1300344:I598_RS11550
uniprot id: A0A168FIL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1300344:I598 RS13475
gene id: 1300344:I598_RS13475
uniprot id: A0A161I8W8
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

1300344:I598 RS13970
gene id: 1300344:I598_RS13970
uniprot id: A0A168FR49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1300344:I598 RS07725
gene id: 1300344:I598_RS07725
uniprot id: A0A161I1G7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1300344:I598 RS09805
gene id: 1300344:I598_RS09805
uniprot id: A0A161I242
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1300344:I598 RS17165
gene id: 1300344:I598_RS17165
uniprot id: A0A161I1E7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1300344:I598 RS07940
gene id: 1300344:I598_RS07940
uniprot id: A0A161I6P6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300344:I598 RS08920
gene id: 1300344:I598_RS08920
uniprot id: A0A161HY83
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1300344:I598 RS00050
gene id: 1300344:I598_RS00050
uniprot id: A0A161II18
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1300344:I598 RS08945
gene id: 1300344:I598_RS08945
uniprot id: A0A161I749
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS11665
gene id: 1300344:I598_RS11665
uniprot id: A0A161HRG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1300344:I598 RS08105
gene id: 1300344:I598_RS08105
uniprot id: A0A168FAC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1300344:I598 RS10565
gene id: 1300344:I598_RS10565
uniprot id: A0A161HQZ8
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS08155
gene id: 1300344:I598_RS08155
uniprot id: A0A168FAG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1300344:I598 RS16020
gene id: 1300344:I598_RS16020
uniprot id: A0A161IKL6
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1300344:I598 RS04655
gene id: 1300344:I598_RS04655
uniprot id: A0A161IG36
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Tetramer of two alpha and two beta subunits.

1300344:I598 RS11430
gene id: 1300344:I598_RS11430
uniprot id: A0A161IIS6
names: Similarity
messages: Belongs to the peptidase C56 family.

1300344:I598 RS11975
gene id: 1300344:I598_RS11975
uniprot id: A0A168FJJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta sliding clamp family.
messages: Cytoplasm

1300344:I598 RS03815
gene id: 1300344:I598_RS03815
uniprot id: A0A168EQE0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1300344:I598 RS03625
gene id: 1300344:I598_RS03625
uniprot id: A0A168EPF7
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1300344:I598 RS02400
gene id: 1300344:I598_RS02400
uniprot id: A0A168EIF3
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1300344:I598 RS10015
gene id: 1300344:I598_RS10015
uniprot id: A0A161HYM5
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1300344:I598 RS16235
gene id: 1300344:I598_RS16235
uniprot id: A0A161IGQ3
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1300344:I598 RS00485
gene id: 1300344:I598_RS00485
uniprot id: A0A168E7G8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1300344:I598 RS13265
gene id: 1300344:I598_RS13265
uniprot id: A0A161IFH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1300344:I598 RS00135
gene id: 1300344:I598_RS00135
uniprot id: A0A168E526
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1300344:I598 RS04175
gene id: 1300344:I598_RS04175
uniprot id: A0A161IJL8
names: Similarity
messages: Belongs to the UPF0098 family.

1300344:I598 RS08300
gene id: 1300344:I598_RS08300
uniprot id: A0A168FAW9
names: Function
names: Similarity
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.
messages: Belongs to the IucA/IucC family.

1300344:I598 RS04780
gene id: 1300344:I598_RS04780
uniprot id: A0A168EVD3
names: Subcellular Location Annotation
messages: Cytoplasm

1300344:I598 RS02945
gene id: 1300344:I598_RS02945
uniprot id: A0A168EL37
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1300344:I598 RS07475
gene id: 1300344:I598_RS07475
uniprot id: A0A161HXN1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1300344:I598 RS14180
gene id: 1300344:I598_RS14180
uniprot id: A0A161HSE5
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

1300344:I598 RS11805
gene id: 1300344:I598_RS11805
uniprot id: A0A168FJ73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1300344:I598 RS08840
gene id: 1300344:I598_RS08840
uniprot id: A0A161IDK8
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1300344:I598 RS03000
gene id: 1300344:I598_RS03000
uniprot id: A0A168ELF0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300344:I598 RS04455
gene id: 1300344:I598_RS04455
uniprot id: A0A168ETR3
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1300344:I598 RS03205
gene id: 1300344:I598_RS03205
uniprot id: A0A168EMD9
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1300344:I598 RS16970
gene id: 1300344:I598_RS16970
uniprot id: A0A161IL04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1300344:I598 RS06325
gene id: 1300344:I598_RS06325
uniprot id: A0A168F329
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1300344:I598 RS02275
gene id: 1300344:I598_RS02275
uniprot id: A0A161IF67
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1300344:I598 RS05395
gene id: 1300344:I598_RS05395
uniprot id: A0A168EYI4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1300344:I598 RS12760
gene id: 1300344:I598_RS12760
uniprot id: A0A161IFB0
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1300344:I598 RS10550
gene id: 1300344:I598_RS10550
uniprot id: A0A168FGA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1300344:I598 RS10855
gene id: 1300344:I598_RS10855
uniprot id: A0A161IMA1
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS12985
gene id: 1300344:I598_RS12985
uniprot id: A0A161HS02
names: Similarity
messages: Belongs to the peptidase M20A family.

1300344:I598 RS01420
gene id: 1300344:I598_RS01420
uniprot id: A0A168ECD3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1300344:I598 RS10735
gene id: 1300344:I598_RS10735
uniprot id: A0A168FGQ6
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1300344:I598 RS01995
gene id: 1300344:I598_RS01995
uniprot id: A0A161I1C7
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

1300344:I598 RS12545
gene id: 1300344:I598_RS12545
uniprot id: A0A161IJ91
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300344:I598 RS04385
gene id: 1300344:I598_RS04385
uniprot id: A0A168ETF6
names: Similarity
messages: Belongs to the group II decarboxylase family.

1300344:I598 RS06295
gene id: 1300344:I598_RS06295
uniprot id: A0A161HX62
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1300344:I598 RS13370
gene id: 1300344:I598_RS13370
uniprot id: A0A161IFI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1300344:I598 RS12070
gene id: 1300344:I598_RS12070
uniprot id: A0A161IMW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1300344:I598 RS12430
gene id: 1300344:I598_RS12430
uniprot id: A0A168FKW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1300344:I598 RS02445
gene id: 1300344:I598_RS02445
uniprot id: A0A168EIK2
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

1300344:I598 RS08360
gene id: 1300344:I598_RS08360
uniprot id: A0A161I6W1
names: Similarity
messages: Belongs to the UPF0234 family.

1300344:I598 RS13600
gene id: 1300344:I598_RS13600
uniprot id: A0A161HS85
names: Similarity
messages: Belongs to the CsoR family.

1300344:I598 RS06470
gene id: 1300344:I598_RS06470
uniprot id: A0A168F3P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell membrane
messages: Membrane

1300344:I598 RS15565
gene id: 1300344:I598_RS15565
uniprot id: A0A168FX41
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1300344:I598 RS13180
gene id: 1300344:I598_RS13180
uniprot id: A0A168FNF6
names: Similarity
messages: Belongs to the KduI family.

1300344:I598 RS01885
gene id: 1300344:I598_RS01885
uniprot id: A0A168EFF5
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1300344:I598 RS09725
gene id: 1300344:I598_RS09725
uniprot id: A0A161I7F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1300344:I598 RS10135
gene id: 1300344:I598_RS10135
uniprot id: A0A161IE45
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1300344:I598 RS05005
gene id: 1300344:I598_RS05005
uniprot id: A0A168EWP9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1300344:I598 RS10185
gene id: 1300344:I598_RS10185
uniprot id: A0A161IE53
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

1300344:I598 RS06645
gene id: 1300344:I598_RS06645
uniprot id: A0A161HXB6
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

1300344:I598 RS12920
gene id: 1300344:I598_RS12920
uniprot id: A0A161I8Q0
names: Similarity
messages: Belongs to the AHA1 family.

1300344:I598 RS01805
gene id: 1300344:I598_RS01805
uniprot id: A0A168EET2
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1300344:I598 RS08090
gene id: 1300344:I598_RS08090
uniprot id: A0A161I6R7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1300344:I598 RS17115
gene id: 1300344:I598_RS17115
uniprot id: A0A161I1E0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

1300344:I598 RS09840
gene id: 1300344:I598_RS09840
uniprot id: A0A161HQQ5
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS00320
gene id: 1300344:I598_RS00320
uniprot id: A0A168E6A5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1300344:I598 RS14550
gene id: 1300344:I598_RS14550
uniprot id: A0A161IK07
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1300344:I598 RS00965
gene id: 1300344:I598_RS00965
uniprot id: A0A168EA58
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS01350
gene id: 1300344:I598_RS01350
uniprot id: A0A168EC54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1300344:I598 RS16175
gene id: 1300344:I598_RS16175
uniprot id: A0A161IKN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1300344:I598 RS04800
gene id: 1300344:I598_RS04800
uniprot id: A0A161HWG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

1300344:I598 RS16350
gene id: 1300344:I598_RS16350
uniprot id: A0A168FZV1
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS08785
gene id: 1300344:I598_RS08785
uniprot id: A0A168FC07
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1300344:I598 RS05200
gene id: 1300344:I598_RS05200
uniprot id: A0A168EXL4
names: Similarity
messages: Belongs to the peptidase M16 family.

1300344:I598 RS00635
gene id: 1300344:I598_RS00635
uniprot id: A0A168E8B9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1300344:I598 RS08815
gene id: 1300344:I598_RS08815
uniprot id: A0A161HQ87
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300344:I598 RS05210
gene id: 1300344:I598_RS05210
uniprot id: A0A161HWN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1300344:I598 RS06180
gene id: 1300344:I598_RS06180
uniprot id: A0A161IKF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1300344:I598 RS15125
gene id: 1300344:I598_RS15125
uniprot id: A0A168FV80
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

1300344:I598 RS04785
gene id: 1300344:I598_RS04785
uniprot id: A0A161IJV5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1300344:I598 RS16985
gene id: 1300344:I598_RS16985
uniprot id: A0A161IH18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1300344:I598 RS13695
gene id: 1300344:I598_RS13695
uniprot id: A0A168FQC9
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS10305
gene id: 1300344:I598_RS10305
uniprot id: A0A161IM11
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1300344:I598 RS13465
gene id: 1300344:I598_RS13465
uniprot id: A0A168FPD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1300344:I598 RS16935
gene id: 1300344:I598_RS16935
uniprot id: A0A161IH11
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1300344:I598 RS11490
gene id: 1300344:I598_RS11490
uniprot id: A0A161IEQ6
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS02760
gene id: 1300344:I598_RS02760
uniprot id: A0A168EKA1
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Homodimer.

1300344:I598 RS08835
gene id: 1300344:I598_RS08835
uniprot id: A0A168FC46
names: Similarity
messages: Belongs to the thymidine kinase family.

1300344:I598 RS03670
gene id: 1300344:I598_RS03670
uniprot id: A0A168EPP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1300344:I598 RS09605
gene id: 1300344:I598_RS09605
uniprot id: A0A161II37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.

1300344:I598 RS02970
gene id: 1300344:I598_RS02970
uniprot id: A0A168ELA8
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1300344:I598 RS02130
gene id: 1300344:I598_RS02130
uniprot id: A0A161HZ99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1300344:I598 RS07190
gene id: 1300344:I598_RS07190
uniprot id: A0A161I1N4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1300344:I598 RS02290
gene id: 1300344:I598_RS02290
uniprot id: A0A168EI14
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1300344:I598 RS15820
gene id: 1300344:I598_RS15820
uniprot id: A0A161IKI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1300344:I598 RS01370
gene id: 1300344:I598_RS01370
uniprot id: A0A168EC86
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1300344:I598 RS05760
gene id: 1300344:I598_RS05760
uniprot id: A0A168F049
names: Similarity
messages: Belongs to the peptidase M13 family.

1300344:I598 RS17185
gene id: 1300344:I598_RS17185
uniprot id: A0A161IH52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1300344:I598 RS10360
gene id: 1300344:I598_RS10360
uniprot id: A0A168FFU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polysaccharide lyase 1 family.
messages: Secreted

1300344:I598 RS07955
gene id: 1300344:I598_RS07955
uniprot id: A0A161IDC5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1300344:I598 RS00340
gene id: 1300344:I598_RS00340
uniprot id: A0A168E6E8
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1300344:I598 RS12255
gene id: 1300344:I598_RS12255
uniprot id: A0A161IF42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1300344:I598 RS07355
gene id: 1300344:I598_RS07355
uniprot id: A0A168F8D3
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1300344:I598 RS05470
gene id: 1300344:I598_RS05470
uniprot id: A0A161IGH8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1300344:I598 RS06285
gene id: 1300344:I598_RS06285
uniprot id: A0A168F2U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1300344:I598 RS07450
gene id: 1300344:I598_RS07450
uniprot id: A0A161I6I2
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1300344:I598 RS12170
gene id: 1300344:I598_RS12170
uniprot id: A0A161IMX8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300344:I598 RS06825
gene id: 1300344:I598_RS06825
uniprot id: A0A168F5T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1300344:I598 RS08475
gene id: 1300344:I598_RS08475
uniprot id: A0A168FB88
names: Similarity
messages: Belongs to the peptidase A24 family.

1300344:I598 RS16380
gene id: 1300344:I598_RS16380
uniprot id: A0A168FZZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1300344:I598 RS13980
gene id: 1300344:I598_RS13980
uniprot id: A0A161HSC4
names: Similarity
messages: Belongs to the HSP15 family.

1300344:I598 RS06355
gene id: 1300344:I598_RS06355
uniprot id: A0A161IGV9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

1300344:I598 RS12460
gene id: 1300344:I598_RS12460
uniprot id: A0A161IF69
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1300344:I598 RS03050
gene id: 1300344:I598_RS03050
uniprot id: A0A168ELN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1300344:I598 RS08250
gene id: 1300344:I598_RS08250
uniprot id: A0A168FAS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1300344:I598 RS17010
gene id: 1300344:I598_RS17010
uniprot id: A0A161HTB0
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1300344:I598 RS06785
gene id: 1300344:I598_RS06785
uniprot id: A0A168F5I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1300344:I598 RS06640
gene id: 1300344:I598_RS06640
uniprot id: A0A168F4S1
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

1300344:I598 RS04515
gene id: 1300344:I598_RS04515
uniprot id: A0A168EU21
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS03685
gene id: 1300344:I598_RS03685
uniprot id: A0A161IFP1
names: Similarity
messages: Belongs to the YciI family.

1300344:I598 RS03680
gene id: 1300344:I598_RS03680
uniprot id: A0A161HVX4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1300344:I598 RS15085
gene id: 1300344:I598_RS15085
uniprot id: A0A168FV34
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1300344:I598 RS05135
gene id: 1300344:I598_RS05135
uniprot id: A0A168EXC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1300344:I598 RS05000
gene id: 1300344:I598_RS05000
uniprot id: A0A168EWN6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300344:I598 RS15390
gene id: 1300344:I598_RS15390
uniprot id: A0A168FWJ0
names: Similarity
messages: Belongs to the universal stress protein A family.

1300344:I598 RS13150
gene id: 1300344:I598_RS13150
uniprot id: A0A161I2Y9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1300344:I598 RS08485
gene id: 1300344:I598_RS08485
uniprot id: A0A161HY20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1300344:I598 RS05335
gene id: 1300344:I598_RS05335
uniprot id: A0A168EY98
names: Similarity
messages: Belongs to the DprA/Smf family.

1300344:I598 RS03080
gene id: 1300344:I598_RS03080
uniprot id: A0A161HVN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

1300344:I598 RS05375
gene id: 1300344:I598_RS05375
uniprot id: A0A161I0L1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1300344:I598 RS04320
gene id: 1300344:I598_RS04320
uniprot id: A0A168ET35
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS14525
gene id: 1300344:I598_RS14525
uniprot id: A0A168FT49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1300344:I598 RS16720
gene id: 1300344:I598_RS16720
uniprot id: A0A161IKX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1300344:I598 RS03055
gene id: 1300344:I598_RS03055
uniprot id: A0A168ELQ4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1300344:I598 RS12185
gene id: 1300344:I598_RS12185
uniprot id: A0A161HZF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1300344:I598 RS00140
gene id: 1300344:I598_RS00140
uniprot id: A0A168E551
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS10910
gene id: 1300344:I598_RS10910
uniprot id: A0A161IMB2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

1300344:I598 RS11640
gene id: 1300344:I598_RS11640
uniprot id: A0A161IES9
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS06780
gene id: 1300344:I598_RS06780
uniprot id: A0A161IKM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1300344:I598 RS16320
gene id: 1300344:I598_RS16320
uniprot id: A0A161IKR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1300344:I598 RS12795
gene id: 1300344:I598_RS12795
uniprot id: A0A161I2V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1300344:I598 RS10105
gene id: 1300344:I598_RS10105
uniprot id: A0A168FF84
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1300344:I598 RS11885
gene id: 1300344:I598_RS11885
uniprot id: A0A161HZC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1300344:I598 RS05345
gene id: 1300344:I598_RS05345
uniprot id: A0A168EYB2
names: Similarity
messages: Belongs to the UPF0102 family.

1300344:I598 RS09115
gene id: 1300344:I598_RS09115
uniprot id: A0A161HQC5
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

1300344:I598 RS15505
gene id: 1300344:I598_RS15505
uniprot id: A0A161IKE3
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1300344:I598 RS16410
gene id: 1300344:I598_RS16410
uniprot id: A0A161HT39
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1300344:I598 RS10625
gene id: 1300344:I598_RS10625
uniprot id: A0A161IIF5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1300344:I598 RS15450
gene id: 1300344:I598_RS15450
uniprot id: A0A161I0R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1300344:I598 RS06435
gene id: 1300344:I598_RS06435
uniprot id: A0A168F3J0
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS02720
gene id: 1300344:I598_RS02720
uniprot id: A0A168EK00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1300344:I598 RS08495
gene id: 1300344:I598_RS08495
uniprot id: A0A161I1P3
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS03005
gene id: 1300344:I598_RS03005
uniprot id: A0A168ELF9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1300344:I598 RS08160
gene id: 1300344:I598_RS08160
uniprot id: A0A161HQ14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1300344:I598 RS05245
gene id: 1300344:I598_RS05245
uniprot id: A0A168EXU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1300344:I598 RS08290
gene id: 1300344:I598_RS08290
uniprot id: A0A161IDC3
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

1300344:I598 RS01380
gene id: 1300344:I598_RS01380
uniprot id: A0A161I159
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1300344:I598 RS05750
gene id: 1300344:I598_RS05750
uniprot id: A0A168F031
names: Similarity
messages: Belongs to the FPG family.

1300344:I598 RS15175
gene id: 1300344:I598_RS15175
uniprot id: A0A161I9F3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

1300344:I598 RS01245
gene id: 1300344:I598_RS01245
uniprot id: A0A161IIF2
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1300344:I598 RS14325
gene id: 1300344:I598_RS14325
uniprot id: A0A168FSG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1300344:I598 RS05635
gene id: 1300344:I598_RS05635
uniprot id: A0A168EZJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1300344:I598 RS02645
gene id: 1300344:I598_RS02645
uniprot id: A0A168EJJ3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1300344:I598 RS02910
gene id: 1300344:I598_RS02910
uniprot id: A0A168EKZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1300344:I598 RS17840
gene id: 1300344:I598_RS17840
uniprot id: A0A168F7F1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1300344:I598 RS16880
gene id: 1300344:I598_RS16880
uniprot id: A0A161IH05
names: Similarity
messages: Belongs to the PrpD family.

1300344:I598 RS07905
gene id: 1300344:I598_RS07905
uniprot id: A0A161IDB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

1300344:I598 RS12650
gene id: 1300344:I598_RS12650
uniprot id: A0A161I2T8
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS04625
gene id: 1300344:I598_RS04625
uniprot id: A0A168EUL4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1300344:I598 RS09845
gene id: 1300344:I598_RS09845
uniprot id: A0A161HYK4
names: Similarity
messages: Belongs to the PhoU family.
messages: Belongs to the UPF0111 family.

1300344:I598 RS11245
gene id: 1300344:I598_RS11245
uniprot id: A0A161IEK9
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1300344:I598 RS16490
gene id: 1300344:I598_RS16490
uniprot id: A0A161I9Y5
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

1300344:I598 RS00865
gene id: 1300344:I598_RS00865
uniprot id: A0A168E9M8
names: Similarity
messages: Belongs to the ketopantoate reductase family.

1300344:I598 RS04960
gene id: 1300344:I598_RS04960
uniprot id: A0A161HWJ1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1300344:I598 RS00480
gene id: 1300344:I598_RS00480
uniprot id: A0A168E7F1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1300344:I598 RS13045
gene id: 1300344:I598_RS13045
uniprot id: A0A161IJG3
names: Similarity
messages: Belongs to the UPF0225 family.

1300344:I598 RS12285
gene id: 1300344:I598_RS12285
uniprot id: A0A161HZH3
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

1300344:I598 RS14415
gene id: 1300344:I598_RS14415
uniprot id: A0A161IFW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1300344:I598 RS12055
gene id: 1300344:I598_RS12055
uniprot id: A0A161IEZ9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1300344:I598 RS00360
gene id: 1300344:I598_RS00360
uniprot id: A0A161I0S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane

1300344:I598 RS06020
gene id: 1300344:I598_RS06020
uniprot id: A0A168F1A3
names: Similarity
messages: Belongs to the GroES chaperonin family.

1300344:I598 RS07840
gene id: 1300344:I598_RS07840
uniprot id: A0A161I6N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm

1300344:I598 RS02715
gene id: 1300344:I598_RS02715
uniprot id: A0A161IJ15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1300344:I598 RS16190
gene id: 1300344:I598_RS16190
uniprot id: A0A161I9U3
names: Similarity
messages: Belongs to the YciI family.

1300344:I598 RS15335
gene id: 1300344:I598_RS15335
uniprot id: A0A168FWA7
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1300344:I598 RS15005
gene id: 1300344:I598_RS15005
uniprot id: A0A161I3E7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1300344:I598 RS00350
gene id: 1300344:I598_RS00350
uniprot id: A0A168E6I4
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1300344:I598 RS00855
gene id: 1300344:I598_RS00855
uniprot id: A0A168E9K7
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1300344:I598 RS06120
gene id: 1300344:I598_RS06120
uniprot id: A0A168F1V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1300344:I598 RS11695
gene id: 1300344:I598_RS11695
uniprot id: A0A161I851
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1300344:I598 RS17280
gene id: 1300344:I598_RS17280
uniprot id: A0A168G306
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

1300344:I598 RS02185
gene id: 1300344:I598_RS02185
uniprot id: A0A168EHD6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1300344:I598 RS16585
gene id: 1300344:I598_RS16585
uniprot id: A0A161IGW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1300344:I598 RS08215
gene id: 1300344:I598_RS08215
uniprot id: A0A161HXY7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1300344:I598 RS15325
gene id: 1300344:I598_RS15325
uniprot id: A0A161I9H0
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.

1300344:I598 RS08115
gene id: 1300344:I598_RS08115
uniprot id: A0A161HXX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1300344:I598 RS02835
gene id: 1300344:I598_RS02835
uniprot id: A0A161IFD8
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1300344:I598 RS02685
gene id: 1300344:I598_RS02685
uniprot id: A0A161IFB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Belongs to the peptidase S8 family.
messages: Cytoplasm

1300344:I598 RS17100
gene id: 1300344:I598_RS17100
uniprot id: A0A168G2C0
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

1300344:I598 RS06170
gene id: 1300344:I598_RS06170
uniprot id: A0A168F282
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

1300344:I598 RS08590
gene id: 1300344:I598_RS08590
uniprot id: A0A161I1Q2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

1300344:I598 RS00095
gene id: 1300344:I598_RS00095
uniprot id: A0A168E4T8
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

1300344:I598 RS03630
gene id: 1300344:I598_RS03630
uniprot id: A0A161HVW7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

1300344:I598 RS15455
gene id: 1300344:I598_RS15455
uniprot id: A0A161IKD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1300344:I598 RS03135
gene id: 1300344:I598_RS03135
uniprot id: A0A161IFH7
names: Similarity
messages: Belongs to the AHA1 family.

1300344:I598 RS08795
gene id: 1300344:I598_RS08795
uniprot id: A0A161I723
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS16185
gene id: 1300344:I598_RS16185
uniprot id: A0A161IGP5
names: Similarity
messages: Belongs to the YciI family.

1300344:I598 RS07680
gene id: 1300344:I598_RS07680
uniprot id: A0A168F981
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1300344:I598 RS04920
gene id: 1300344:I598_RS04920
uniprot id: A0A161I0D5
names: Subcellular Location Annotation
messages: Cytoplasm

1300344:I598 RS01195
gene id: 1300344:I598_RS01195
uniprot id: A0A161IIE5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1300344:I598 RS02780
gene id: 1300344:I598_RS02780
uniprot id: A0A161HVJ3
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS03025
gene id: 1300344:I598_RS03025
uniprot id: A0A168ELL6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1300344:I598 RS05265
gene id: 1300344:I598_RS05265
uniprot id: A0A161HWP4
names: Similarity
messages: Belongs to the FPG family.

1300344:I598 RS15535
gene id: 1300344:I598_RS15535
uniprot id: A0A168FX16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1300344:I598 RS01815
gene id: 1300344:I598_RS01815
uniprot id: A0A168EEZ3
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1300344:I598 RS07555
gene id: 1300344:I598_RS07555
uniprot id: A0A168F8Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1300344:I598 RS11105
gene id: 1300344:I598_RS11105
uniprot id: A0A168FHH6
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS15525
gene id: 1300344:I598_RS15525
uniprot id: A0A161I9J7
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

1300344:I598 RS10125
gene id: 1300344:I598_RS10125
uniprot id: A0A161I269
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Belongs to the acyl-CoA oxidase family.

1300344:I598 RS14835
gene id: 1300344:I598_RS14835
uniprot id: A0A168FU53
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1300344:I598 RS13700
gene id: 1300344:I598_RS13700
uniprot id: A0A161HS95
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS14780
gene id: 1300344:I598_RS14780
uniprot id: A0A168FTZ4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1300344:I598 RS02200
gene id: 1300344:I598_RS02200
uniprot id: A0A168EHN1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1300344:I598 RS02305
gene id: 1300344:I598_RS02305
uniprot id: A0A161IIW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1300344:I598 RS03505
gene id: 1300344:I598_RS03505
uniprot id: A0A168ENT0
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300344:I598 RS00255
gene id: 1300344:I598_RS00255
uniprot id: A0A168E5T7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300344:I598 RS02940
gene id: 1300344:I598_RS02940
uniprot id: A0A161HZK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1300344:I598 RS02545
gene id: 1300344:I598_RS02545
uniprot id: A0A168EJ06
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300344:I598 RS14380
gene id: 1300344:I598_RS14380
uniprot id: A0A161HSG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1300344:I598 RS10440
gene id: 1300344:I598_RS10440
uniprot id: A0A161IE92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1300344:I598 RS04475
gene id: 1300344:I598_RS04475
uniprot id: A0A161IJR2
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1300344:I598 RS04070
gene id: 1300344:I598_RS04070
uniprot id: A0A168ERU8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1300344:I598 RS13775
gene id: 1300344:I598_RS13775
uniprot id: A0A168FQJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1300344:I598 RS02085
gene id: 1300344:I598_RS02085
uniprot id: A0A168EGS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

1300344:I598 RS18335
gene id: 1300344:I598_RS18335
uniprot id: A0A168FRN0
names: Subcellular Location Annotation
messages: Cytoplasm

1300344:I598 RS10895
gene id: 1300344:I598_RS10895
uniprot id: A0A161IEF6
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS05995
gene id: 1300344:I598_RS05995
uniprot id: A0A161I0V6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1300344:I598 RS10280
gene id: 1300344:I598_RS10280
uniprot id: A0A161I278
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1300344:I598 RS01725
gene id: 1300344:I598_RS01725
uniprot id: A0A168EED6
names: Similarity
messages: Belongs to the glutamine synthetase family.

1300344:I598 RS13515
gene id: 1300344:I598_RS13515
uniprot id: A0A161I319
names: Function
names: Similarity
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

1300344:I598 RS06615
gene id: 1300344:I598_RS06615
uniprot id: A0A168F4I3
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1300344:I598 RS07665
gene id: 1300344:I598_RS07665
uniprot id: A0A161HXQ7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300344:I598 RS08050
gene id: 1300344:I598_RS08050
uniprot id: A0A161IL54
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1300344:I598 RS15915
gene id: 1300344:I598_RS15915
uniprot id: A0A161HSX7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1300344:I598 RS11040
gene id: 1300344:I598_RS11040
uniprot id: A0A168FHB8
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

1300344:I598 RS10235
gene id: 1300344:I598_RS10235
uniprot id: A0A161IE59
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1300344:I598 RS05125
gene id: 1300344:I598_RS05125
uniprot id: A0A168EX91
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1300344:I598 RS11690
gene id: 1300344:I598_RS11690
uniprot id: A0A161IET6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1300344:I598 RS16120
gene id: 1300344:I598_RS16120
uniprot id: A0A161I115
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1300344:I598 RS08145
gene id: 1300344:I598_RS08145
uniprot id: A0A168FAE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1300344:I598 RS08525
gene id: 1300344:I598_RS08525
uniprot id: A0A168FBD5
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1300344:I598 RS01250
gene id: 1300344:I598_RS01250
uniprot id: A0A168EBJ2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1300344:I598 RS16610
gene id: 1300344:I598_RS16610
uniprot id: A0A161HT63
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

1300344:I598 RS07850
gene id: 1300344:I598_RS07850
uniprot id: A0A161IL26
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1300344:I598 RS13245
gene id: 1300344:I598_RS13245
uniprot id: A0A161HZU3
names: Similarity
messages: Belongs to the YciI family.

1300344:I598 RS01225
gene id: 1300344:I598_RS01225
uniprot id: A0A168EBD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1300344:I598 RS08165
gene id: 1300344:I598_RS08165
uniprot id: A0A161HXY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1300344:I598 RS01865
gene id: 1300344:I598_RS01865
uniprot id: A0A168EFA5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

1300344:I598 RS13620
gene id: 1300344:I598_RS13620
uniprot id: A0A168FPX5
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

1300344:I598 RS03595
gene id: 1300344:I598_RS03595
uniprot id: A0A168EP74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1300344:I598 RS02665
gene id: 1300344:I598_RS02665
uniprot id: A0A161IJ09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1300344:I598 RS07185
gene id: 1300344:I598_RS07185
uniprot id: A0A161I6E9
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

1300344:I598 RS07745
gene id: 1300344:I598_RS07745
uniprot id: A0A168F9E3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300344:I598 RS06650
gene id: 1300344:I598_RS06650
uniprot id: A0A161IH02
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS17250
gene id: 1300344:I598_RS17250
uniprot id: A0A168G2V7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1300344:I598 RS03930
gene id: 1300344:I598_RS03930
uniprot id: A0A168ER37
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1300344:I598 RS05745
gene id: 1300344:I598_RS05745
uniprot id: A0A168F010
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300344:I598 RS12710
gene id: 1300344:I598_RS12710
uniprot id: A0A161IFA3
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1300344:I598 RS07015
gene id: 1300344:I598_RS07015
uniprot id: A0A168F6W3
names: Similarity
messages: Belongs to the universal stress protein A family.

1300344:I598 RS08370
gene id: 1300344:I598_RS08370
uniprot id: A0A161IL92
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS05090
gene id: 1300344:I598_RS05090
uniprot id: A0A168EX35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1300344:I598 RS09110
gene id: 1300344:I598_RS09110
uniprot id: A0A168FCU1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

1300344:I598 RS12525
gene id: 1300344:I598_RS12525
uniprot id: A0A168FL73
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

1300344:I598 RS01950
gene id: 1300344:I598_RS01950
uniprot id: A0A161IIR2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'P' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Non-allosteric.

1300344:I598 RS01875
gene id: 1300344:I598_RS01875
uniprot id: A0A168EFC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1300344:I598 RS10380
gene id: 1300344:I598_RS10380
uniprot id: A0A161I285
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1300344:I598 RS17240
gene id: 1300344:I598_RS17240
uniprot id: A0A161IA77
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1300344:I598 RS04660
gene id: 1300344:I598_RS04660
uniprot id: A0A161I090
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1300344:I598 RS13100
gene id: 1300344:I598_RS13100
uniprot id: A0A161I2Y5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1300344:I598 RS04085
gene id: 1300344:I598_RS04085
uniprot id: A0A168ERW9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1300344:I598 RS00740
gene id: 1300344:I598_RS00740
uniprot id: A0A168E8X0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1300344:I598 RS10320
gene id: 1300344:I598_RS10320
uniprot id: A0A161HYR3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

1300344:I598 RS15555
gene id: 1300344:I598_RS15555
uniprot id: A0A161IKF1
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

1300344:I598 RS16180
gene id: 1300344:I598_RS16180
uniprot id: A0A161I3N2
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

1300344:I598 RS17300
gene id: 1300344:I598_RS17300
uniprot id: A0A168G368
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

1300344:I598 RS11600
gene id: 1300344:I598_RS11600
uniprot id: A0A168FIQ4
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS07005
gene id: 1300344:I598_RS07005
uniprot id: A0A161IH63
names: Similarity
messages: Belongs to the SufE family.

1300344:I598 RS16940
gene id: 1300344:I598_RS16940
uniprot id: A0A161IA40
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1300344:I598 RS16155
gene id: 1300344:I598_RS16155
uniprot id: A0A168FZ70
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1300344:I598 RS05370
gene id: 1300344:I598_RS05370
uniprot id: A0A161IGG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1300344:I598 RS05560
gene id: 1300344:I598_RS05560
uniprot id: A0A168EZ91
names: Similarity
messages: Belongs to the CutA family.

1300344:I598 RS10620
gene id: 1300344:I598_RS10620
uniprot id: A0A161HYV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1300344:I598 RS17170
gene id: 1300344:I598_RS17170
uniprot id: A0A161IL35
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

1300344:I598 RS10335
gene id: 1300344:I598_RS10335
uniprot id: A0A168FFR5
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1300344:I598 RS13440
gene id: 1300344:I598_RS13440
uniprot id: A0A161IF64
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

1300344:I598 RS16075
gene id: 1300344:I598_RS16075
uniprot id: A0A161IKM4
names: Similarity
messages: Belongs to the YciI family.

1300344:I598 RS02885
gene id: 1300344:I598_RS02885
uniprot id: A0A161IFE6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300344:I598 RS07920
gene id: 1300344:I598_RS07920
uniprot id: A0A161IHH7
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1300344:I598 RS08740
gene id: 1300344:I598_RS08740
uniprot id: A0A161IDJ5
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1300344:I598 RS05410
gene id: 1300344:I598_RS05410
uniprot id: A0A168EYK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1300344:I598 RS03730
gene id: 1300344:I598_RS03730
uniprot id: A0A161HVY2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300344:I598 RS09795
gene id: 1300344:I598_RS09795
uniprot id: A0A161HYK0
names: Similarity
messages: Belongs to the GSP E family.

1300344:I598 RS01495
gene id: 1300344:I598_RS01495
uniprot id: A0A161I174
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS15685
gene id: 1300344:I598_RS15685
uniprot id: A0A161IGH1
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1300344:I598 RS02320
gene id: 1300344:I598_RS02320
uniprot id: A0A161HVD6
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1300344:I598 RS08030
gene id: 1300344:I598_RS08030
uniprot id: A0A168FA36
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1300344:I598 RS13365
gene id: 1300344:I598_RS13365
uniprot id: A0A168FP10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

1300344:I598 RS13750
gene id: 1300344:I598_RS13750
uniprot id: A0A168FQH9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

1300344:I598 RS01795
gene id: 1300344:I598_RS01795
uniprot id: A0A161I1A7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1300344:I598 RS16960
gene id: 1300344:I598_RS16960
uniprot id: A0A161HTA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1300344:I598 RS17910
gene id: 1300344:I598_RS17910
uniprot id: A0A161I8H5
names: Similarity
messages: Belongs to the UPF0749 family.

1300344:I598 RS06155
gene id: 1300344:I598_RS06155
uniprot id: A0A161I0X7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homotetramer.

1300344:I598 RS03600
gene id: 1300344:I598_RS03600
uniprot id: A0A168EP92
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1300344:I598 RS11675
gene id: 1300344:I598_RS11675
uniprot id: A0A161IIW1
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

1300344:I598 RS06570
gene id: 1300344:I598_RS06570
uniprot id: A0A168F460
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1300344:I598 RS08130
gene id: 1300344:I598_RS08130
uniprot id: A0A168FAD6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1300344:I598 RS03560
gene id: 1300344:I598_RS03560
uniprot id: A0A168EP37
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1300344:I598 RS14855
gene id: 1300344:I598_RS14855
uniprot id: A0A161I3D3
names: Similarity
messages: Belongs to the UPF0045 family.

1300344:I598 RS11895
gene id: 1300344:I598_RS11895
uniprot id: A0A161I2L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1300344:I598 RS08755
gene id: 1300344:I598_RS08755
uniprot id: A0A161ILE5
names: Similarity
messages: Belongs to the peptidase S33 family.

1300344:I598 RS04310
gene id: 1300344:I598_RS04310
uniprot id: A0A168ET08
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300344:I598 RS16995
gene id: 1300344:I598_RS16995
uniprot id: A0A168G204
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1300344:I598 RS03695
gene id: 1300344:I598_RS03695
uniprot id: A0A168EPS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1300344:I598 RS15965
gene id: 1300344:I598_RS15965
uniprot id: A0A161HSY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1300344:I598 RS14895
gene id: 1300344:I598_RS14895
uniprot id: A0A161I0H6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1300344:I598 RS00695
gene id: 1300344:I598_RS00695
uniprot id: A0A161IEE4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1300344:I598 RS08335
gene id: 1300344:I598_RS08335
uniprot id: A0A168FAZ4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1300344:I598 RS03955
gene id: 1300344:I598_RS03955
uniprot id: A0A168ER58
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

1300344:I598 RS07980
gene id: 1300344:I598_RS07980
uniprot id: A0A168F9X8
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1300344:I598 RS01345
gene id: 1300344:I598_RS01345
uniprot id: A0A168EC46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.

1300344:I598 RS10325
gene id: 1300344:I598_RS10325
uniprot id: A0A161IIA9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300344:I598 RS12445
gene id: 1300344:I598_RS12445
uniprot id: A0A161IJ80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1300344:I598 RS15770
gene id: 1300344:I598_RS15770
uniprot id: A0A161I3J9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1300344:I598 RS08135
gene id: 1300344:I598_RS08135
uniprot id: A0A161ID92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1300344:I598 RS15220
gene id: 1300344:I598_RS15220
uniprot id: A0A161IG84
names: Similarity
messages: Belongs to the peptidase S8 family.

1300344:I598 RS04135
gene id: 1300344:I598_RS04135
uniprot id: A0A168ES73
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS16870
gene id: 1300344:I598_RS16870
uniprot id: A0A161I3T8
names: Similarity
messages: Belongs to the citrate synthase family.

1300344:I598 RS08220
gene id: 1300344:I598_RS08220
uniprot id: A0A161IHK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1300344:I598 RS03665
gene id: 1300344:I598_RS03665
uniprot id: A0A161IJF0
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

1300344:I598 RS07760
gene id: 1300344:I598_RS07760
uniprot id: A0A161HPW2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1300344:I598 RS08580
gene id: 1300344:I598_RS08580
uniprot id: A0A161HY35
names: Similarity
messages: Belongs to the peptidase S1C family.

1300344:I598 RS16280
gene id: 1300344:I598_RS16280
uniprot id: A0A168FZK8
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1300344:I598 RS05300
gene id: 1300344:I598_RS05300
uniprot id: A0A161IK30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1300344:I598 RS12470
gene id: 1300344:I598_RS12470
uniprot id: A0A168FKZ4
names: Similarity
messages: Belongs to the ParB family.

1300344:I598 RS04045
gene id: 1300344:I598_RS04045
uniprot id: A0A161IFU3
names: Similarity
messages: Belongs to the AHA1 family.

1300344:I598 RS18290
gene id: 1300344:I598_RS18290
uniprot id: A0A168F955
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS08195
gene id: 1300344:I598_RS08195
uniprot id: A0A168FAL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1300344:I598 RS16580
gene id: 1300344:I598_RS16580
uniprot id: A0A168G0P8
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

1300344:I598 RS05980
gene id: 1300344:I598_RS05980
uniprot id: A0A168F169
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300344:I598 RS10165
gene id: 1300344:I598_RS10165
uniprot id: A0A161HYP2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1300344:I598 RS01895
gene id: 1300344:I598_RS01895
uniprot id: A0A161I1B7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

1300344:I598 RS04790
gene id: 1300344:I598_RS04790
uniprot id: A0A168EVG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1300344:I598 RS07300
gene id: 1300344:I598_RS07300
uniprot id: A0A161I6G2
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS16735
gene id: 1300344:I598_RS16735
uniprot id: A0A161IGY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1300344:I598 RS00125
gene id: 1300344:I598_RS00125
uniprot id: A0A161IE58
names: Similarity
messages: Belongs to the cytochrome P450 family.

1300344:I598 RS17560
gene id: 1300344:I598_RS17560
uniprot id: A0A168EQK9
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

1300344:I598 RS02905
gene id: 1300344:I598_RS02905
uniprot id: A0A168EKY2
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS01450
gene id: 1300344:I598_RS01450
uniprot id: A0A168ECI7
names: Similarity
messages: Belongs to the CdaR family.

1300344:I598 RS11720
gene id: 1300344:I598_RS11720
uniprot id: A0A161HZA1
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

1300344:I598 RS13965
gene id: 1300344:I598_RS13965
uniprot id: A0A168FR21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1300344:I598 RS02840
gene id: 1300344:I598_RS02840
uniprot id: A0A161HZI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1300344:I598 RS08315
gene id: 1300344:I598_RS08315
uniprot id: A0A161HQ32
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

1300344:I598 RS10475
gene id: 1300344:I598_RS10475
uniprot id: A0A161IID3
names: Similarity
messages: Belongs to the pirin family.

1300344:I598 RS08280
gene id: 1300344:I598_RS08280
uniprot id: A0A161I1M2
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS00275
gene id: 1300344:I598_RS00275
uniprot id: A0A168E5Z3
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1300344:I598 RS12435
gene id: 1300344:I598_RS12435
uniprot id: A0A161HRS6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1300344:I598 RS08070
gene id: 1300344:I598_RS08070
uniprot id: A0A161IHJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1300344:I598 RS06725
gene id: 1300344:I598_RS06725
uniprot id: A0A168F578
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1300344:I598 RS12405
gene id: 1300344:I598_RS12405
uniprot id: A0A168FKR8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1300344:I598 RS15180
gene id: 1300344:I598_RS15180
uniprot id: A0A168FVM4
names: Similarity
messages: Belongs to the WXG100 family.

1300344:I598 RS03155
gene id: 1300344:I598_RS03155
uniprot id: A0A168EM58
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1300344:I598 RS09720
gene id: 1300344:I598_RS09720
uniprot id: A0A161IDZ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

1300344:I598 RS06895
gene id: 1300344:I598_RS06895
uniprot id: A0A168F671
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1300344:I598 RS04290
gene id: 1300344:I598_RS04290
uniprot id: A0A161HW70
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1300344:I598 RS04510
gene id: 1300344:I598_RS04510
uniprot id: A0A168EU12
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300344:I598 RS08170
gene id: 1300344:I598_RS08170
uniprot id: A0A161IHK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1300344:I598 RS03195
gene id: 1300344:I598_RS03195
uniprot id: A0A168EMB4
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

1300344:I598 RS06720
gene id: 1300344:I598_RS06720
uniprot id: A0A168F560
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1300344:I598 RS15695
gene id: 1300344:I598_RS15695
uniprot id: A0A168FXF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1300344:I598 RS08470
gene id: 1300344:I598_RS08470
uniprot id: A0A161ILA6
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1300344:I598 RS10330
gene id: 1300344:I598_RS10330
uniprot id: A0A161I282
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1300344:I598 RS01085
gene id: 1300344:I598_RS01085
uniprot id: A0A161IIC9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1300344:I598 RS04665
gene id: 1300344:I598_RS04665
uniprot id: A0A168EUQ5
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1300344:I598 RS15065
gene id: 1300344:I598_RS15065
uniprot id: A0A161IG61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1300344:I598 RS06680
gene id: 1300344:I598_RS06680
uniprot id: A0A161IKL5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1300344:I598 RS07615
gene id: 1300344:I598_RS07615
uniprot id: A0A161HPU3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1300344:I598 RS08630
gene id: 1300344:I598_RS08630
uniprot id: A0A161IHQ8
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS03720
gene id: 1300344:I598_RS03720
uniprot id: A0A168EPX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1300344:I598 RS14010
gene id: 1300344:I598_RS14010
uniprot id: A0A161I922
names: Similarity
messages: Belongs to the universal stress protein A family.

1300344:I598 RS14085
gene id: 1300344:I598_RS14085
uniprot id: A0A161I040
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1300344:I598 RS16875
gene id: 1300344:I598_RS16875
uniprot id: A0A168G1P8
names: Function
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.

1300344:I598 RS16975
gene id: 1300344:I598_RS16975
uniprot id: A0A161I3U7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1300344:I598 RS06050
gene id: 1300344:I598_RS06050
uniprot id: A0A161HX23
names: Similarity
messages: Belongs to the thioredoxin family.

1300344:I598 RS06930
gene id: 1300344:I598_RS06930
uniprot id: A0A168F6D8
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS10245
gene id: 1300344:I598_RS10245
uniprot id: A0A168FFJ2
names: Similarity
messages: Belongs to the peptidase S8 family.

1300344:I598 RS17095
gene id: 1300344:I598_RS17095
uniprot id: A0A168G2A5
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

1300344:I598 RS11260
gene id: 1300344:I598_RS11260
uniprot id: A0A161IMH3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily.

1300344:I598 RS06770
gene id: 1300344:I598_RS06770
uniprot id: A0A168F5G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

1300344:I598 RS16785
gene id: 1300344:I598_RS16785
uniprot id: A0A161IGY9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1300344:I598 RS07480
gene id: 1300344:I598_RS07480
uniprot id: A0A161IHC8
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS14930
gene id: 1300344:I598_RS14930
uniprot id: A0A168FUG5
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1300344:I598 RS09785
gene id: 1300344:I598_RS09785
uniprot id: A0A168FEI2
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS10240
gene id: 1300344:I598_RS10240
uniprot id: A0A161I7M7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1300344:I598 RS07565
gene id: 1300344:I598_RS07565
uniprot id: A0A161HPT6
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1300344:I598 RS12165
gene id: 1300344:I598_RS12165
uniprot id: A0A168FJX8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1300344:I598 RS07140
gene id: 1300344:I598_RS07140
uniprot id: A0A168F7Q0
names: Similarity
messages: Belongs to the DEAD box helicase family.

1300344:I598 RS00775
gene id: 1300344:I598_RS00775
uniprot id: A0A161II87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1300344:I598 RS15910
gene id: 1300344:I598_RS15910
uniprot id: A0A168FYA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1300344:I598 RS08185
gene id: 1300344:I598_RS08185
uniprot id: A0A161IDA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1300344:I598 RS13920
gene id: 1300344:I598_RS13920
uniprot id: A0A168FQX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1300344:I598 RS13645
gene id: 1300344:I598_RS13645
uniprot id: A0A168FQ20
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300344:I598 RS01155
gene id: 1300344:I598_RS01155
uniprot id: A0A168EB01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1300344:I598 RS15375
gene id: 1300344:I598_RS15375
uniprot id: A0A161I9H6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

1300344:I598 RS11565
gene id: 1300344:I598_RS11565
uniprot id: A0A161HRF2
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1300344:I598 RS09565
gene id: 1300344:I598_RS09565
uniprot id: A0A168FDV3
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1300344:I598 RS12450
gene id: 1300344:I598_RS12450
uniprot id: A0A161I2R9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1300344:I598 RS00975
gene id: 1300344:I598_RS00975
uniprot id: A0A161I108
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

1300344:I598 RS01055
gene id: 1300344:I598_RS01055
uniprot id: A0A161IEK0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1300344:I598 RS00860
gene id: 1300344:I598_RS00860
uniprot id: A0A168E9L7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1300344:I598 RS02820
gene id: 1300344:I598_RS02820
uniprot id: A0A168EKK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

1300344:I598 RS07490
gene id: 1300344:I598_RS07490
uniprot id: A0A168F8Q5
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1300344:I598 RS08055
gene id: 1300344:I598_RS08055
uniprot id: A0A161IDF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1300344:I598 RS00980
gene id: 1300344:I598_RS00980
uniprot id: A0A161IIB3
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS08750
gene id: 1300344:I598_RS08750
uniprot id: A0A168FBW4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300344:I598 RS00990
gene id: 1300344:I598_RS00990
uniprot id: A0A168EA96
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300344:I598 RS04675
gene id: 1300344:I598_RS04675
uniprot id: A0A168EUU3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1300344:I598 RS02455
gene id: 1300344:I598_RS02455
uniprot id: A0A168EIN3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1300344:I598 RS15365
gene id: 1300344:I598_RS15365
uniprot id: A0A168FWD5
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS03570
gene id: 1300344:I598_RS03570
uniprot id: A0A168EP54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1300344:I598 RS00705
gene id: 1300344:I598_RS00705
uniprot id: A0A168E8P9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1300344:I598 RS00500
gene id: 1300344:I598_RS00500
uniprot id: A0A168E7L3
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1300344:I598 RS06200
gene id: 1300344:I598_RS06200
uniprot id: A0A161IGT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1300344:I598 RS08640
gene id: 1300344:I598_RS08640
uniprot id: A0A168FBM6
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS10210
gene id: 1300344:I598_RS10210
uniprot id: A0A161HQW2
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1300344:I598 RS12420
gene id: 1300344:I598_RS12420
uniprot id: A0A168FKS8
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

1300344:I598 RS04835
gene id: 1300344:I598_RS04835
uniprot id: A0A161IJW3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300344:I598 RS08950
gene id: 1300344:I598_RS08950
uniprot id: A0A168FCH2
names: Similarity
messages: Belongs to the UxaA family.

1300344:I598 RS00735
gene id: 1300344:I598_RS00735
uniprot id: A0A168E8W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1300344:I598 RS14475
gene id: 1300344:I598_RS14475
uniprot id: A0A168FSX7
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1300344:I598 RS02865
gene id: 1300344:I598_RS02865
uniprot id: A0A161IJ35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1300344:I598 RS06475
gene id: 1300344:I598_RS06475
uniprot id: A0A168F3Q7
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1300344:I598 RS05130
gene id: 1300344:I598_RS05130
uniprot id: A0A168EXA7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1300344:I598 RS04540
gene id: 1300344:I598_RS04540
uniprot id: A0A161HWA9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300344:I598 RS14890
gene id: 1300344:I598_RS14890
uniprot id: A0A161HSL3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1300344:I598 RS02540
gene id: 1300344:I598_RS02540
uniprot id: A0A161HZE5
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

1300344:I598 RS06925
gene id: 1300344:I598_RS06925
uniprot id: A0A168F6C2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1300344:I598 RS00305
gene id: 1300344:I598_RS00305
uniprot id: A0A168E692
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1300344:I598 RS03610
gene id: 1300344:I598_RS03610
uniprot id: A0A168EPC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1300344:I598 RS05780
gene id: 1300344:I598_RS05780
uniprot id: A0A161I0S1
names: Similarity
messages: Belongs to the peptidase M1 family.

1300344:I598 RS07950
gene id: 1300344:I598_RS07950
uniprot id: A0A161IL39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1300344:I598 RS05430
gene id: 1300344:I598_RS05430
uniprot id: A0A168EYM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1300344:I598 RS04245
gene id: 1300344:I598_RS04245
uniprot id: A0A161IFX6
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS00615
gene id: 1300344:I598_RS00615
uniprot id: A0A168E898
names: Similarity
messages: Belongs to the group II decarboxylase family.

1300344:I598 RS11615
gene id: 1300344:I598_RS11615
uniprot id: A0A161HRG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1300344:I598 RS16095
gene id: 1300344:I598_RS16095
uniprot id: A0A161I9S6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1300344:I598 RS01020
gene id: 1300344:I598_RS01020
uniprot id: A0A168EAD4
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1300344:I598 RS08675
gene id: 1300344:I598_RS08675
uniprot id: A0A161HY49
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1300344:I598 RS06345
gene id: 1300344:I598_RS06345
uniprot id: A0A168F351
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

1300344:I598 RS09825
gene id: 1300344:I598_RS09825
uniprot id: A0A168FEM2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1300344:I598 RS03220
gene id: 1300344:I598_RS03220
uniprot id: A0A168EMH8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

1300344:I598 RS12790
gene id: 1300344:I598_RS12790
uniprot id: A0A161IJC7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1300344:I598 RS05315
gene id: 1300344:I598_RS05315
uniprot id: A0A161HWQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1300344:I598 RS00130
gene id: 1300344:I598_RS00130
uniprot id: A0A168E501
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

1300344:I598 RS05120
gene id: 1300344:I598_RS05120
uniprot id: A0A161I0H1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1300344:I598 RS15000
gene id: 1300344:I598_RS15000
uniprot id: A0A161IK69
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1300344:I598 RS13870
gene id: 1300344:I598_RS13870
uniprot id: A0A168FQQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1300344:I598 RS04735
gene id: 1300344:I598_RS04735
uniprot id: A0A161IJU8
names: Function
names: Subcellular Location Annotation
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

1300344:I598 RS11010
gene id: 1300344:I598_RS11010
uniprot id: A0A161IMD3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1300344:I598 RS12740
gene id: 1300344:I598_RS12740
uniprot id: A0A161HZN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

1300344:I598 RS05385
gene id: 1300344:I598_RS05385
uniprot id: A0A168EYE9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1300344:I598 RS13425
gene id: 1300344:I598_RS13425
uniprot id: A0A161I8W2
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

1300344:I598 RS11320
gene id: 1300344:I598_RS11320
uniprot id: A0A161HRC1
names: Subcellular Location Annotation
messages: Cell membrane

1300344:I598 RS05440
gene id: 1300344:I598_RS05440
uniprot id: A0A168EYQ2
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS08600
gene id: 1300344:I598_RS08600
uniprot id: A0A161I6Z7
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300344:I598 RS04810
gene id: 1300344:I598_RS04810
uniprot id: A0A161I0B7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1300344:I598 RS07455
gene id: 1300344:I598_RS07455
uniprot id: A0A168F8P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1300344:I598 RS11575
gene id: 1300344:I598_RS11575
uniprot id: A0A161IIU6
names: Similarity
messages: In the N-terminal section; belongs to the phytochrome family.

1300344:I598 RS00825
gene id: 1300344:I598_RS00825
uniprot id: A0A161I0Z0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1300344:I598 RS08025
gene id: 1300344:I598_RS08025
uniprot id: A0A161I1J9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1300344:I598 RS11610
gene id: 1300344:I598_RS11610
uniprot id: A0A168FIR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1300344:I598 RS05305
gene id: 1300344:I598_RS05305
uniprot id: A0A168EY43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1300344:I598 RS11545
gene id: 1300344:I598_RS11545
uniprot id: A0A161I834
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1300344:I598 RS05930
gene id: 1300344:I598_RS05930
uniprot id: A0A168F0Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1300344:I598 RS03870
gene id: 1300344:I598_RS03870
uniprot id: A0A161IJH8
names: Similarity
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Homohexamer. Assembles into a hexameric ring structure.

1300344:I598 RS07210
gene id: 1300344:I598_RS07210
uniprot id: A0A161HXK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1300344:I598 RS08100
gene id: 1300344:I598_RS08100
uniprot id: A0A161IL59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1300344:I598 RS05320
gene id: 1300344:I598_RS05320
uniprot id: A0A161IGF0
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1300344:I598 RS15035
gene id: 1300344:I598_RS15035
uniprot id: A0A168FUW7
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1300344:I598 RS04970
gene id: 1300344:I598_RS04970
uniprot id: A0A161I0E7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1300344:I598 RS14915
gene id: 1300344:I598_RS14915
uniprot id: A0A161IG34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1300344:I598 RS06820
gene id: 1300344:I598_RS06820
uniprot id: A0A168F5R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1300344:I598 RS01150
gene id: 1300344:I598_RS01150
uniprot id: A0A168EAY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1300344:I598 RS04610
gene id: 1300344:I598_RS04610
uniprot id: A0A161I083
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300344:I598 RS03485
gene id: 1300344:I598_RS03485
uniprot id: A0A161IFL7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1300344:I598 RS16390
gene id: 1300344:I598_RS16390
uniprot id: A0A161I9X1
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1300344:I598 RS06310
gene id: 1300344:I598_RS06310
uniprot id: A0A168F2W3
names: Similarity
messages: Belongs to the DSD1 family.

1300344:I598 RS05715
gene id: 1300344:I598_RS05715
uniprot id: A0A168EZX2
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1300344:I598 RS02120
gene id: 1300344:I598_RS02120
uniprot id: A0A161HVA9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300344:I598 RS12480
gene id: 1300344:I598_RS12480
uniprot id: A0A168FL27
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1300344:I598 RS06990
gene id: 1300344:I598_RS06990
uniprot id: A0A168F6S8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1300344:I598 RS10050
gene id: 1300344:I598_RS10050
uniprot id: A0A161ILX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1300344:I598 RS01435
gene id: 1300344:I598_RS01435
uniprot id: A0A168ECH5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1300344:I598 RS00225
gene id: 1300344:I598_RS00225
uniprot id: A0A168E5L5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1300344:I598 RS02695
gene id: 1300344:I598_RS02695
uniprot id: A0A168EJT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1300344:I598 RS12090
gene id: 1300344:I598_RS12090
uniprot id: A0A161IJ22
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1300344:I598 RS13195
gene id: 1300344:I598_RS13195
uniprot id: A0A161HZT8
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS07540
gene id: 1300344:I598_RS07540
uniprot id: A0A168F8X2
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS07795
gene id: 1300344:I598_RS07795
uniprot id: A0A168F9H0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1300344:I598 RS05285
gene id: 1300344:I598_RS05285
uniprot id: A0A168EXZ9
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300344:I598 RS01440
gene id: 1300344:I598_RS01440
uniprot id: A0A161I165
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1300344:I598 RS04495
gene id: 1300344:I598_RS04495
uniprot id: A0A161IG17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1300344:I598 RS06575
gene id: 1300344:I598_RS06575
uniprot id: A0A168F479
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1300344:I598 RS11085
gene id: 1300344:I598_RS11085
uniprot id: A0A161I2D6
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

1300344:I598 RS15815
gene id: 1300344:I598_RS15815
uniprot id: A0A161I0W6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1300344:I598 RS16790
gene id: 1300344:I598_RS16790
uniprot id: A0A161IA21
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS06840
gene id: 1300344:I598_RS06840
uniprot id: A0A168F5W0
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1300344:I598 RS08175
gene id: 1300344:I598_RS08175
uniprot id: A0A161I1L4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1300344:I598 RS16030
gene id: 1300344:I598_RS16030
uniprot id: A0A161I3L8
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS12330
gene id: 1300344:I598_RS12330
uniprot id: A0A168FKJ9
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS16315
gene id: 1300344:I598_RS16315
uniprot id: A0A161I140
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1300344:I598 RS16405
gene id: 1300344:I598_RS16405
uniprot id: A0A168G030
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

1300344:I598 RS13205
gene id: 1300344:I598_RS13205
uniprot id: A0A161I2Z4
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS01280
gene id: 1300344:I598_RS01280
uniprot id: A0A168EBS6
names: Similarity
messages: Belongs to the Fur family.

1300344:I598 RS17825
gene id: 1300344:I598_RS17825
uniprot id: A0A168F0C5
names: Similarity
messages: Belongs to the type IB topoisomerase family.

1300344:I598 RS12425
gene id: 1300344:I598_RS12425
uniprot id: A0A168FKU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1300344:I598 RS01680
gene id: 1300344:I598_RS01680
uniprot id: A0A168EE54
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

1300344:I598 RS01900
gene id: 1300344:I598_RS01900
uniprot id: A0A161IIQ4
names: Caution
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

1300344:I598 RS08235
gene id: 1300344:I598_RS08235
uniprot id: A0A161IDB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1300344:I598 RS17045
gene id: 1300344:I598_RS17045
uniprot id: A0A168G251
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

1300344:I598 RS12785
gene id: 1300344:I598_RS12785
uniprot id: A0A161HRX5
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS12025
gene id: 1300344:I598_RS12025
uniprot id: A0A168FJN2
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS11005
gene id: 1300344:I598_RS11005
uniprot id: A0A168FH91
names: Similarity
messages: Belongs to the UPF0303 family.

1300344:I598 RS03545
gene id: 1300344:I598_RS03545
uniprot id: A0A168ENX7
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1300344:I598 RS10095
gene id: 1300344:I598_RS10095
uniprot id: A0A168FF66
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1300344:I598 RS16420
gene id: 1300344:I598_RS16420
uniprot id: A0A161IKS7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1300344:I598 RS05075
gene id: 1300344:I598_RS05075
uniprot id: A0A168EWY9
names: Similarity
messages: Belongs to the FPG family.

1300344:I598 RS16000
gene id: 1300344:I598_RS16000
uniprot id: A0A168FYK9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1300344:I598 RS15395
gene id: 1300344:I598_RS15395
uniprot id: A0A161HSR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1300344:I598 RS01220
gene id: 1300344:I598_RS01220
uniprot id: A0A168EBB7
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS02955
gene id: 1300344:I598_RS02955
uniprot id: A0A168EL81
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1300344:I598 RS13760
gene id: 1300344:I598_RS13760
uniprot id: A0A161HZZ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1300344:I598 RS00075
gene id: 1300344:I598_RS00075
uniprot id: A0A161IE51
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

1300344:I598 RS06335
gene id: 1300344:I598_RS06335
uniprot id: A0A161IKG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1300344:I598 RS06860
gene id: 1300344:I598_RS06860
uniprot id: A0A161I171
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1300344:I598 RS09145
gene id: 1300344:I598_RS09145
uniprot id: A0A161I775
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

1300344:I598 RS02860
gene id: 1300344:I598_RS02860
uniprot id: A0A168EKR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1300344:I598 RS06590
gene id: 1300344:I598_RS06590
uniprot id: A0A168F4D0
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

1300344:I598 RS07640
gene id: 1300344:I598_RS07640
uniprot id: A0A161I6K6
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS09260
gene id: 1300344:I598_RS09260
uniprot id: A0A168FD73
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS04815
gene id: 1300344:I598_RS04815
uniprot id: A0A168EVN0
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1300344:I598 RS02880
gene id: 1300344:I598_RS02880
uniprot id: A0A161HVL0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1300344:I598 RS05340
gene id: 1300344:I598_RS05340
uniprot id: A0A168EYA4
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1300344:I598 RS08875
gene id: 1300344:I598_RS08875
uniprot id: A0A161IHU5
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1300344:I598 RS08490
gene id: 1300344:I598_RS08490
uniprot id: A0A161IHN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1300344:I598 RS08095
gene id: 1300344:I598_RS08095
uniprot id: A0A168FAA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1300344:I598 RS16165
gene id: 1300344:I598_RS16165
uniprot id: A0A161HT07
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1300344:I598 RS08060
gene id: 1300344:I598_RS08060
uniprot id: A0A161HQ02
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1300344:I598 RS02525
gene id: 1300344:I598_RS02525
uniprot id: A0A168EIZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1300344:I598 RS10070
gene id: 1300344:I598_RS10070
uniprot id: A0A161II79
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1300344:I598 RS08665
gene id: 1300344:I598_RS08665
uniprot id: A0A168FBQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1300344:I598 RS08500
gene id: 1300344:I598_RS08500
uniprot id: A0A168FBA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1300344:I598 RS16630
gene id: 1300344:I598_RS16630
uniprot id: A0A168G0W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1300344:I598 RS05380
gene id: 1300344:I598_RS05380
uniprot id: A0A168EYE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

1300344:I598 RS13615
gene id: 1300344:I598_RS13615
uniprot id: A0A161I329
names: Similarity
messages: Belongs to the ALAD family.

1300344:I598 RS02515
gene id: 1300344:I598_RS02515
uniprot id: A0A161IIY8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1300344:I598 RS03775
gene id: 1300344:I598_RS03775
uniprot id: A0A168EQ49
names: Similarity
messages: Belongs to the glutamate synthase family.

1300344:I598 RS04880
gene id: 1300344:I598_RS04880
uniprot id: A0A168EW24
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1300344:I598 RS00950
gene id: 1300344:I598_RS00950
uniprot id: A0A161IEI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

1300344:I598 RS14745
gene id: 1300344:I598_RS14745
uniprot id: A0A161IK33
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1300344:I598 RS01780
gene id: 1300344:I598_RS01780
uniprot id: A0A168EEQ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1300344:I598 RS14995
gene id: 1300344:I598_RS14995
uniprot id: A0A161I0J1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate, the first step in the de novo biosynthesis of NAD(+).
messages: Cytoplasm

1300344:I598 RS04585
gene id: 1300344:I598_RS04585
uniprot id: A0A161IJS7
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1300344:I598 RS06215
gene id: 1300344:I598_RS06215
uniprot id: A0A168F2G4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1300344:I598 RS14920
gene id: 1300344:I598_RS14920
uniprot id: A0A161I9B5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1300344:I598 RS04855
gene id: 1300344:I598_RS04855
uniprot id: A0A161IG71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1300344:I598 RS04275
gene id: 1300344:I598_RS04275
uniprot id: A0A161IJN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1300344:I598 RS16965
gene id: 1300344:I598_RS16965
uniprot id: A0A161I1C1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1300344:I598 RS09220
gene id: 1300344:I598_RS09220
uniprot id: A0A161HYC7
names: Similarity
messages: Belongs to the universal stress protein A family.

1300344:I598 RS00550
gene id: 1300344:I598_RS00550
uniprot id: A0A168E7X6
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS04535
gene id: 1300344:I598_RS04535
uniprot id: A0A168EU67
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1300344:I598 RS10850
gene id: 1300344:I598_RS10850
uniprot id: A0A168FH06
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1300344:I598 RS12365
gene id: 1300344:I598_RS12365
uniprot id: A0A168FKM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

1300344:I598 RS02830
gene id: 1300344:I598_RS02830
uniprot id: A0A161HVK1
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS06695
gene id: 1300344:I598_RS06695
uniprot id: A0A161HXC2
names: Similarity
messages: Belongs to the LOG family.

1300344:I598 RS04055
gene id: 1300344:I598_RS04055
uniprot id: A0A168ERN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

1300344:I598 RS10080
gene id: 1300344:I598_RS10080
uniprot id: A0A168FF58
names: Similarity
messages: Belongs to the Dps family.

1300344:I598 RS04905
gene id: 1300344:I598_RS04905
uniprot id: A0A161HWI3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1300344:I598 RS03335
gene id: 1300344:I598_RS03335
uniprot id: A0A161HZQ7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1300344:I598 RS16855
gene id: 1300344:I598_RS16855
uniprot id: A0A161HT95
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS03810
gene id: 1300344:I598_RS03810
uniprot id: A0A168EQA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1300344:I598 RS12400
gene id: 1300344:I598_RS12400
uniprot id: A0A161I2R5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1300344:I598 RS11750
gene id: 1300344:I598_RS11750
uniprot id: A0A161IMR0
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

1300344:I598 RS04615
gene id: 1300344:I598_RS04615
uniprot id: A0A168EUJ0
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1300344:I598 RS12520
gene id: 1300344:I598_RS12520
uniprot id: A0A168FL58
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS16340
gene id: 1300344:I598_RS16340
uniprot id: A0A161I9W5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1300344:I598 RS14340
gene id: 1300344:I598_RS14340
uniprot id: A0A161IJY0
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS15500
gene id: 1300344:I598_RS15500
uniprot id: A0A161I0S4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1300344:I598 RS07325
gene id: 1300344:I598_RS07325
uniprot id: A0A161HXL4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

1300344:I598 RS09810
gene id: 1300344:I598_RS09810
uniprot id: A0A168FEK6
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300344:I598 RS15130
gene id: 1300344:I598_RS15130
uniprot id: A0A168FVE1
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

1300344:I598 RS08860
gene id: 1300344:I598_RS08860
uniprot id: A0A168FC86
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1300344:I598 RS04950
gene id: 1300344:I598_RS04950
uniprot id: A0A168EWF4
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1300344:I598 RS11485
gene id: 1300344:I598_RS11485
uniprot id: A0A168FIG6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

1300344:I598 RS06460
gene id: 1300344:I598_RS06460
uniprot id: A0A168F3L2
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1300344:I598 RS01985
gene id: 1300344:I598_RS01985
uniprot id: A0A168EG29
names: Similarity
messages: Belongs to the universal stress protein A family.

1300344:I598 RS03660
gene id: 1300344:I598_RS03660
uniprot id: A0A168EPL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1300344:I598 RS03920
gene id: 1300344:I598_RS03920
uniprot id: A0A161IJI4
names: Similarity
messages: Belongs to the fructosamine kinase family.

1300344:I598 RS07825
gene id: 1300344:I598_RS07825
uniprot id: A0A161I1H8
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS05950
gene id: 1300344:I598_RS05950
uniprot id: A0A168F0Z3
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1300344:I598 RS17230
gene id: 1300344:I598_RS17230
uniprot id: A0A168G2Q8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

1300344:I598 RS08935
gene id: 1300344:I598_RS08935
uniprot id: A0A168FCE7
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS07790
gene id: 1300344:I598_RS07790
uniprot id: A0A161I6M5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1300344:I598 RS05415
gene id: 1300344:I598_RS05415
uniprot id: A0A161HWR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1300344:I598 RS06540
gene id: 1300344:I598_RS06540
uniprot id: A0A168F431
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1300344:I598 RS07435
gene id: 1300344:I598_RS07435
uniprot id: A0A161I1D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1300344:I598 RS14900
gene id: 1300344:I598_RS14900
uniprot id: A0A161IK56
names: Similarity
messages: Belongs to the peptidase S13 family.

1300344:I598 RS14405
gene id: 1300344:I598_RS14405
uniprot id: A0A161I398
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1300344:I598 RS01240
gene id: 1300344:I598_RS01240
uniprot id: A0A161I139
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1300344:I598 RS00670
gene id: 1300344:I598_RS00670
uniprot id: A0A161I0W7
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

1300344:I598 RS05645
gene id: 1300344:I598_RS05645
uniprot id: A0A168EZL4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1300344:I598 RS07420
gene id: 1300344:I598_RS07420
uniprot id: A0A161HPR8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1300344:I598 RS00055
gene id: 1300344:I598_RS00055
uniprot id: A0A168E4K7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1300344:I598 RS08120
gene id: 1300344:I598_RS08120
uniprot id: A0A161IHJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1300344:I598 RS04725
gene id: 1300344:I598_RS04725
uniprot id: A0A168EV44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1300344:I598 RS01310
gene id: 1300344:I598_RS01310
uniprot id: A0A168EC00
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

1300344:I598 RS02100
gene id: 1300344:I598_RS02100
uniprot id: A0A161IIU1
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

1300344:I598 RS12870
gene id: 1300344:I598_RS12870
uniprot id: A0A168FME1
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS07730
gene id: 1300344:I598_RS07730
uniprot id: A0A168F9C4
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

1300344:I598 RS08015
gene id: 1300344:I598_RS08015
uniprot id: A0A161HXV7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1300344:I598 RS06885
gene id: 1300344:I598_RS06885
uniprot id: A0A161IKP4
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1300344:I598 RS03845
gene id: 1300344:I598_RS03845
uniprot id: A0A161HZW8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

1300344:I598 RS17005
gene id: 1300344:I598_RS17005
uniprot id: A0A168G229
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

1300344:I598 RS01675
gene id: 1300344:I598_RS01675
uniprot id: A0A168EE37
names: Similarity
messages: Belongs to the glutamine synthetase family.

1300344:I598 RS04460
gene id: 1300344:I598_RS04460
uniprot id: A0A168ETT1
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1300344:I598 RS06545
gene id: 1300344:I598_RS06545
uniprot id: A0A161HXA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.

1300344:I598 RS08535
gene id: 1300344:I598_RS08535
uniprot id: A0A161HY28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1300344:I598 RS17260
gene id: 1300344:I598_RS17260
uniprot id: A0A168G2Z7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1300344:I598 RS15550
gene id: 1300344:I598_RS15550
uniprot id: A0A161I0T2
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

1300344:I598 RS08710
gene id: 1300344:I598_RS08710
uniprot id: A0A168FBT2
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1300344:I598 RS10055
gene id: 1300344:I598_RS10055
uniprot id: A0A168FF45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1300344:I598 RS06550
gene id: 1300344:I598_RS06550
uniprot id: A0A161IGY7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1300344:I598 RS16485
gene id: 1300344:I598_RS16485
uniprot id: A0A161IGU5
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

1300344:I598 RS07405
gene id: 1300344:I598_RS07405
uniprot id: A0A168F8J1
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS01215
gene id: 1300344:I598_RS01215
uniprot id: A0A161IEM7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1300344:I598 RS14725
gene id: 1300344:I598_RS14725
uniprot id: A0A168FTS1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1300344:I598 RS12075
gene id: 1300344:I598_RS12075
uniprot id: A0A168FJR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1300344:I598 RS12065
gene id: 1300344:I598_RS12065
uniprot id: A0A168FJQ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1300344:I598 RS03635
gene id: 1300344:I598_RS03635
uniprot id: A0A161IFN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

1300344:I598 RS07510
gene id: 1300344:I598_RS07510
uniprot id: A0A161IKY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1300344:I598 RS16665
gene id: 1300344:I598_RS16665
uniprot id: A0A161I186
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS04860
gene id: 1300344:I598_RS04860
uniprot id: A0A161I0C6
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300344:I598 RS03425
gene id: 1300344:I598_RS03425
uniprot id: A0A168ENF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1300344:I598 RS00700
gene id: 1300344:I598_RS00700
uniprot id: A0A168E8P3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1300344:I598 RS01870
gene id: 1300344:I598_RS01870
uniprot id: A0A161IF04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1300344:I598 RS04435
gene id: 1300344:I598_RS04435
uniprot id: A0A168ETQ0
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

1300344:I598 RS07870
gene id: 1300344:I598_RS07870
uniprot id: A0A161IHH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family.
messages: Cell membrane
messages: Membrane

1300344:I598 RS08065
gene id: 1300344:I598_RS08065
uniprot id: A0A161HXW7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1300344:I598 RS07860
gene id: 1300344:I598_RS07860
uniprot id: A0A161HPX7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300344:I598 RS16915
gene id: 1300344:I598_RS16915
uniprot id: A0A161I1B6
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1300344:I598 RS07430
gene id: 1300344:I598_RS07430
uniprot id: A0A161IHC4
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1300344:I598 RS01430
gene id: 1300344:I598_RS01430
uniprot id: A0A168ECG0
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1300344:I598 RS12625
gene id: 1300344:I598_RS12625
uniprot id: A0A168FLI2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1300344:I598 RS15560
gene id: 1300344:I598_RS15560
uniprot id: A0A161I3I5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Cytoplasm
messages: Homotetramer.

1300344:I598 RS04840
gene id: 1300344:I598_RS04840
uniprot id: A0A168EVW1
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS00120
gene id: 1300344:I598_RS00120
uniprot id: A0A168E4Y3
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1300344:I598 RS03405
gene id: 1300344:I598_RS03405
uniprot id: A0A168ENB9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1300344:I598 RS02520
gene id: 1300344:I598_RS02520
uniprot id: A0A168EIY5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1300344:I598 RS03850
gene id: 1300344:I598_RS03850
uniprot id: A0A168EQI9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

1300344:I598 RS11115
gene id: 1300344:I598_RS11115
uniprot id: A0A168FHJ0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1300344:I598 RS06660
gene id: 1300344:I598_RS06660
uniprot id: A0A168F4T2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300344:I598 RS13605
gene id: 1300344:I598_RS13605
uniprot id: A0A161HZY1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1300344:I598 RS02555
gene id: 1300344:I598_RS02555
uniprot id: A0A168EJ29
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.

1300344:I598 RS16655
gene id: 1300344:I598_RS16655
uniprot id: A0A168G108
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1300344:I598 RS08715
gene id: 1300344:I598_RS08715
uniprot id: A0A161HQ75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions.

1300344:I598 RS08150
gene id: 1300344:I598_RS08150
uniprot id: A0A161IL66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1300344:I598 RS09615
gene id: 1300344:I598_RS09615
uniprot id: A0A168FDY6
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

1300344:I598 RS00565
gene id: 1300344:I598_RS00565
uniprot id: A0A168E804
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS03765
gene id: 1300344:I598_RS03765
uniprot id: A0A168EQ40
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

1300344:I598 RS12540
gene id: 1300344:I598_RS12540
uniprot id: A0A161HZK9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1300344:I598 RS13850
gene id: 1300344:I598_RS13850
uniprot id: A0A161I348
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1300344:I598 RS03020
gene id: 1300344:I598_RS03020
uniprot id: A0A168ELJ9
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1300344:I598 RS00325
gene id: 1300344:I598_RS00325
uniprot id: A0A168E6C0
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1300344:I598 RS05355
gene id: 1300344:I598_RS05355
uniprot id: A0A168EYC4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1300344:I598 RS04240
gene id: 1300344:I598_RS04240
uniprot id: A0A161HW64
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1300344:I598 RS11465
gene id: 1300344:I598_RS11465
uniprot id: A0A168FIF6
names: Similarity
messages: Belongs to the CsoR family.

1300344:I598 RS06235
gene id: 1300344:I598_RS06235
uniprot id: A0A168F2J8
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1300344:I598 RS01860
gene id: 1300344:I598_RS01860
uniprot id: A0A168EF87
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1300344:I598 RS08440
gene id: 1300344:I598_RS08440
uniprot id: A0A161IHN1
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS10970
gene id: 1300344:I598_RS10970
uniprot id: A0A161HR44
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

1300344:I598 RS04680
gene id: 1300344:I598_RS04680
uniprot id: A0A168EUV4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1300344:I598 RS09590
gene id: 1300344:I598_RS09590
uniprot id: A0A168FDX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1300344:I598 RS13690
gene id: 1300344:I598_RS13690
uniprot id: A0A168FQA8
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family.

1300344:I598 RS15435
gene id: 1300344:I598_RS15435
uniprot id: A0A168FWP0
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1300344:I598 RS05505
gene id: 1300344:I598_RS05505
uniprot id: A0A168EZ05
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS01605
gene id: 1300344:I598_RS01605
uniprot id: A0A168EDE9
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1300344:I598 RS16245
gene id: 1300344:I598_RS16245
uniprot id: A0A168FZG5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300344:I598 RS08085
gene id: 1300344:I598_RS08085
uniprot id: A0A161ID82
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1300344:I598 RS07045
gene id: 1300344:I598_RS07045
uniprot id: A0A168F762
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1300344:I598 RS14495
gene id: 1300344:I598_RS14495
uniprot id: A0A161I0A5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300344:I598 RS10865
gene id: 1300344:I598_RS10865
uniprot id: A0A161HR36
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1300344:I598 RS07805
gene id: 1300344:I598_RS07805
uniprot id: A0A161ID83
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

1300344:I598 RS07770
gene id: 1300344:I598_RS07770
uniprot id: A0A161IHG2
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

1300344:I598 RS11225
gene id: 1300344:I598_RS11225
uniprot id: A0A161HZ40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

1300344:I598 RS04130
gene id: 1300344:I598_RS04130
uniprot id: A0A168ES57
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS16780
gene id: 1300344:I598_RS16780
uniprot id: A0A168G1D0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1300344:I598 RS01270
gene id: 1300344:I598_RS01270
uniprot id: A0A168EBQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1300344:I598 RS08075
gene id: 1300344:I598_RS08075
uniprot id: A0A161I1K3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1300344:I598 RS17215
gene id: 1300344:I598_RS17215
uniprot id: A0A161I1F5
names: Similarity
messages: Belongs to the glycosyl hydrolase.

1300344:I598 RS06220
gene id: 1300344:I598_RS06220
uniprot id: A0A168F2H6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1300344:I598 RS10890
gene id: 1300344:I598_RS10890
uniprot id: A0A168FH30
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

1300344:I598 RS04580
gene id: 1300344:I598_RS04580
uniprot id: A0A168EUC7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300344:I598 RS00800
gene id: 1300344:I598_RS00800
uniprot id: A0A168E9C7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1300344:I598 RS04630
gene id: 1300344:I598_RS04630
uniprot id: A0A168EUM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1300344:I598 RS11385
gene id: 1300344:I598_RS11385
uniprot id: A0A161I2G6
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS07125
gene id: 1300344:I598_RS07125
uniprot id: A0A168F7L2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1300344:I598 RS07975
gene id: 1300344:I598_RS07975
uniprot id: A0A161I1J5
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1300344:I598 RS14570
gene id: 1300344:I598_RS14570
uniprot id: A0A161I976
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS07605
gene id: 1300344:I598_RS07605
uniprot id: A0A161IKZ4
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

1300344:I598 RS12620
gene id: 1300344:I598_RS12620
uniprot id: A0A168FLH4
names: Similarity
messages: Belongs to the peptidase S8 family.

1300344:I598 RS02700
gene id: 1300344:I598_RS02700
uniprot id: A0A168EJV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1300344:I598 RS03045
gene id: 1300344:I598_RS03045
uniprot id: A0A168ELM6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1300344:I598 RS05045
gene id: 1300344:I598_RS05045
uniprot id: A0A161IJZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1300344:I598 RS15105
gene id: 1300344:I598_RS15105
uniprot id: A0A161I3F7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1300344:I598 RS07780
gene id: 1300344:I598_RS07780
uniprot id: A0A168F9F8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1300344:I598 RS12415
gene id: 1300344:I598_RS12415
uniprot id: A0A161I8I3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1300344:I598 RS02580
gene id: 1300344:I598_RS02580
uniprot id: A0A161HVF7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1300344:I598 RS01955
gene id: 1300344:I598_RS01955
uniprot id: A0A168EFV1
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

1300344:I598 RS03450
gene id: 1300344:I598_RS03450
uniprot id: A0A168ENJ0
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

1300344:I598 RS05805
gene id: 1300344:I598_RS05805
uniprot id: A0A161IKA2
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1300344:I598 RS03830
gene id: 1300344:I598_RS03830
uniprot id: A0A168EQH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1300344:I598 RS11290
gene id: 1300344:I598_RS11290
uniprot id: A0A168FHZ0
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

1300344:I598 RS06095
gene id: 1300344:I598_RS06095
uniprot id: A0A161HX32
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

1300344:I598 RS03065
gene id: 1300344:I598_RS03065
uniprot id: A0A161IJ65
names: Similarity
messages: Belongs to the DEAD box helicase family.

1300344:I598 RS05220
gene id: 1300344:I598_RS05220
uniprot id: A0A161I0I7
names: Similarity
messages: Belongs to the ribF family.

1300344:I598 RS07715
gene id: 1300344:I598_RS07715
uniprot id: A0A161HXR3
names: Similarity
messages: Belongs to the XFP family.

1300344:I598 RS01970
gene id: 1300344:I598_RS01970
uniprot id: A0A161IF22
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1300344:I598 RS08770
gene id: 1300344:I598_RS08770
uniprot id: A0A161HY64
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS07010
gene id: 1300344:I598_RS07010
uniprot id: A0A161I189
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS05935
gene id: 1300344:I598_RS05935
uniprot id: A0A161HX02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1300344:I598 RS00610
gene id: 1300344:I598_RS00610
uniprot id: A0A168E880
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1300344:I598 RS04985
gene id: 1300344:I598_RS04985
uniprot id: A0A168EWK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1300344:I598 RS06025
gene id: 1300344:I598_RS06025
uniprot id: A0A168F1B7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1300344:I598 RS16910
gene id: 1300344:I598_RS16910
uniprot id: A0A161HT99
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1300344:I598 RS03650
gene id: 1300344:I598_RS03650
uniprot id: A0A168EPI7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1300344:I598 RS05755
gene id: 1300344:I598_RS05755
uniprot id: A0A161IK95
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1300344:I598 RS05235
gene id: 1300344:I598_RS05235
uniprot id: A0A168EXT2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1300344:I598 RS08305
gene id: 1300344:I598_RS08305
uniprot id: A0A161IL85
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

1300344:I598 RS01755
gene id: 1300344:I598_RS01755
uniprot id: A0A168EEK1
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS14775
gene id: 1300344:I598_RS14775
uniprot id: A0A168FTY2
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

1300344:I598 RS07820
gene id: 1300344:I598_RS07820
uniprot id: A0A161IHG4
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS14910
gene id: 1300344:I598_RS14910
uniprot id: A0A168FUD4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1300344:I598 RS08620
gene id: 1300344:I598_RS08620
uniprot id: A0A161HQ65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1300344:I598 RS08375
gene id: 1300344:I598_RS08375
uniprot id: A0A168FB17
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1300344:I598 RS02250
gene id: 1300344:I598_RS02250
uniprot id: A0A168EHU4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

1300344:I598 RS15370
gene id: 1300344:I598_RS15370
uniprot id: A0A161IGB4
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

1300344:I598 RS01400
gene id: 1300344:I598_RS01400
uniprot id: A0A168ECC1
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1300344:I598 RS15800
gene id: 1300344:I598_RS15800
uniprot id: A0A168FXX8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1300344:I598 RS03895
gene id: 1300344:I598_RS03895
uniprot id: A0A161HZX4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

1300344:I598 RS05330
gene id: 1300344:I598_RS05330
uniprot id: A0A168EY70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1300344:I598 RS05230
gene id: 1300344:I598_RS05230
uniprot id: A0A168EXS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1300344:I598 RS13540
gene id: 1300344:I598_RS13540
uniprot id: A0A168FPP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1300344:I598 RS13055
gene id: 1300344:I598_RS13055
uniprot id: A0A168FMW6
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS03375
gene id: 1300344:I598_RS03375
uniprot id: A0A161HVS6
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS05475
gene id: 1300344:I598_RS05475
uniprot id: A0A161I0M9
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS00765
gene id: 1300344:I598_RS00765
uniprot id: A0A168E936
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1300344:I598 RS08140
gene id: 1300344:I598_RS08140
uniprot id: A0A161I6S6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1300344:I598 RS14115
gene id: 1300344:I598_RS14115
uniprot id: A0A168FRR9
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1300344:I598 RS16850
gene id: 1300344:I598_RS16850
uniprot id: A0A168G1N7
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS12770
gene id: 1300344:I598_RS12770
uniprot id: A0A168FM20
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

1300344:I598 RS06135
gene id: 1300344:I598_RS06135
uniprot id: A0A168F200
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

1300344:I598 RS06265
gene id: 1300344:I598_RS06265
uniprot id: A0A168F2P3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300344:I598 RS11685
gene id: 1300344:I598_RS11685
uniprot id: A0A168FIW1
names: Similarity
messages: Belongs to the DapA family.

1300344:I598 RS11280
gene id: 1300344:I598_RS11280
uniprot id: A0A161IIQ6
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

1300344:I598 RS11710
gene id: 1300344:I598_RS11710
uniprot id: A0A168FIY6
names: Similarity
messages: Belongs to the universal stress protein A family.

1300344:I598 RS02245
gene id: 1300344:I598_RS02245
uniprot id: A0A168EHT6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1300344:I598 RS08560
gene id: 1300344:I598_RS08560
uniprot id: A0A168FBG0
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1300344:I598 RS04600
gene id: 1300344:I598_RS04600
uniprot id: A0A161HWC2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300344:I598 RS04090
gene id: 1300344:I598_RS04090
uniprot id: A0A161HW41
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1300344:I598 RS08810
gene id: 1300344:I598_RS08810
uniprot id: A0A168FC31
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1300344:I598 RS00295
gene id: 1300344:I598_RS00295
uniprot id: A0A168E663
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1300344:I598 RS12475
gene id: 1300344:I598_RS12475
uniprot id: A0A168FL08
names: Similarity
messages: Belongs to the thioredoxin family.

1300344:I598 RS15040
gene id: 1300344:I598_RS15040
uniprot id: A0A161HSN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1300344:I598 RS14080
gene id: 1300344:I598_RS14080
uniprot id: A0A161HSD4
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1300344:I598 RS17855
gene id: 1300344:I598_RS17855
uniprot id: A0A161IDD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1300344:I598 RS16990
gene id: 1300344:I598_RS16990
uniprot id: A0A161IA46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1300344:I598 RS08275
gene id: 1300344:I598_RS08275
uniprot id: A0A161IHL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1300344:I598 RS01990
gene id: 1300344:I598_RS01990
uniprot id: A0A168EG46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1300344:I598 RS02855
gene id: 1300344:I598_RS02855
uniprot id: A0A168EKR4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1300344:I598 RS08010
gene id: 1300344:I598_RS08010
uniprot id: A0A161HPZ6
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1300344:I598 RS06125
gene id: 1300344:I598_RS06125
uniprot id: A0A168F1Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1300344:I598 RS00220
gene id: 1300344:I598_RS00220
uniprot id: A0A161II33
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1300344:I598 RS12875
gene id: 1300344:I598_RS12875
uniprot id: A0A168FMF4
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS01905
gene id: 1300344:I598_RS01905
uniprot id: A0A168EFI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1300344:I598 RS15320
gene id: 1300344:I598_RS15320
uniprot id: A0A161IGA6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1300344:I598 RS10085
gene id: 1300344:I598_RS10085
uniprot id: A0A161IE39
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1300344:I598 RS05155
gene id: 1300344:I598_RS05155
uniprot id: A0A168EXG6
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1300344:I598 RS00290
gene id: 1300344:I598_RS00290
uniprot id: A0A168E640
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1300344:I598 RS13625
gene id: 1300344:I598_RS13625
uniprot id: A0A161IFL4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1300344:I598 RS02975
gene id: 1300344:I598_RS02975
uniprot id: A0A168ELB7
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1300344:I598 RS07460
gene id: 1300344:I598_RS07460
uniprot id: A0A161IKX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1300344:I598 RS00650
gene id: 1300344:I598_RS00650
uniprot id: A0A168E8E9
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1300344:I598 RS15315
gene id: 1300344:I598_RS15315
uniprot id: A0A168FW55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

1300344:I598 RS03950
gene id: 1300344:I598_RS03950
uniprot id: A0A168ER47
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS13585
gene id: 1300344:I598_RS13585
uniprot id: A0A168FPT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Membrane

1300344:I598 RS04805
gene id: 1300344:I598_RS04805
uniprot id: A0A161IG63
names: Similarity
messages: Belongs to the YggT family.

1300344:I598 RS08745
gene id: 1300344:I598_RS08745
uniprot id: A0A161I716
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1300344:I598 RS04760
gene id: 1300344:I598_RS04760
uniprot id: A0A161I0A8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1300344:I598 RS08930
gene id: 1300344:I598_RS08930
uniprot id: A0A161I1T9
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

1300344:I598 RS02255
gene id: 1300344:I598_RS02255
uniprot id: A0A161IIW2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

1300344:I598 RS03380
gene id: 1300344:I598_RS03380
uniprot id: A0A161IFK6
names: Subcellular Location Annotation
messages: Membrane

1300344:I598 RS08035
gene id: 1300344:I598_RS08035
uniprot id: A0A161ID69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.