1294273:ROSELON RS16180
gene id: 1294273:ROSELON_RS16180
uniprot id: W8ST79
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1294273:ROSELON RS00190
gene id: 1294273:ROSELON_RS00190
uniprot id: W8RXH6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1294273:ROSELON RS10085
gene id: 1294273:ROSELON_RS10085
uniprot id: W8S2T2
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1294273:ROSELON RS04990
gene id: 1294273:ROSELON_RS04990
uniprot id: W8RQP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1294273:ROSELON RS15590
gene id: 1294273:ROSELON_RS15590
uniprot id: W8RWM7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1294273:ROSELON RS12040
gene id: 1294273:ROSELON_RS12040
uniprot id: W8SQT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1294273:ROSELON RS11700
gene id: 1294273:ROSELON_RS11700
uniprot id: W8RUB9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1294273:ROSELON RS09230
gene id: 1294273:ROSELON_RS09230
uniprot id: W8S296
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1294273:ROSELON RS12185
gene id: 1294273:ROSELON_RS12185
uniprot id: W8SQZ8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1294273:ROSELON RS07740
gene id: 1294273:ROSELON_RS07740
uniprot id: W8RS84
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1294273:ROSELON RS08065
gene id: 1294273:ROSELON_RS08065
uniprot id: W8RSD7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.

1294273:ROSELON RS00290
gene id: 1294273:ROSELON_RS00290
uniprot id: W8RNF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

1294273:ROSELON RS15915
gene id: 1294273:ROSELON_RS15915
uniprot id: W8RWT7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1294273:ROSELON RS05260
gene id: 1294273:ROSELON_RS05260
uniprot id: W8S409
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1294273:ROSELON RS07825
gene id: 1294273:ROSELON_RS07825
uniprot id: W8S5E3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1294273:ROSELON RS07100
gene id: 1294273:ROSELON_RS07100
uniprot id: W8RS00
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1294273:ROSELON RS15850
gene id: 1294273:ROSELON_RS15850
uniprot id: W8RWS2
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1294273:ROSELON RS05525
gene id: 1294273:ROSELON_RS05525
uniprot id: W8S0B3
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1294273:ROSELON RS09280
gene id: 1294273:ROSELON_RS09280
uniprot id: W8S644
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1294273:ROSELON RS02075
gene id: 1294273:ROSELON_RS02075
uniprot id: W8RYH5
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1294273:ROSELON RS08220
gene id: 1294273:ROSELON_RS08220
uniprot id: W8S5L2
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1294273:ROSELON RS08130
gene id: 1294273:ROSELON_RS08130
uniprot id: W8RSK3
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1294273:ROSELON RS04915
gene id: 1294273:ROSELON_RS04915
uniprot id: W8RQW3
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1294273:ROSELON RS14975
gene id: 1294273:ROSELON_RS14975
uniprot id: W8SSJ9
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1294273:ROSELON RS14370
gene id: 1294273:ROSELON_RS14370
uniprot id: W8SS53
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1294273:ROSELON RS06495
gene id: 1294273:ROSELON_RS06495
uniprot id: W8RRP3
names: Similarity
messages: Belongs to the ketopantoate reductase family.

1294273:ROSELON RS07735
gene id: 1294273:ROSELON_RS07735
uniprot id: W8RSE7
names: Function
names: Subcellular Location Annotation
messages: Could be a virulence factor.
messages: Membrane
messages: Secreted

1294273:ROSELON RS14620
gene id: 1294273:ROSELON_RS14620
uniprot id: W8SSE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1294273:ROSELON RS03580
gene id: 1294273:ROSELON_RS03580
uniprot id: W8SKW9
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS04355
gene id: 1294273:ROSELON_RS04355
uniprot id: W8SLB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1294273:ROSELON RS15795
gene id: 1294273:ROSELON_RS15795
uniprot id: W8RWE4
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1294273:ROSELON RS09310
gene id: 1294273:ROSELON_RS09310
uniprot id: W8S2B1
names: Caution
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1294273:ROSELON RS14635
gene id: 1294273:ROSELON_RS14635
uniprot id: W8RVW9
names: Similarity
messages: Belongs to the TrpC family.

1294273:ROSELON RS07330
gene id: 1294273:ROSELON_RS07330
uniprot id: W8SN67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1294273:ROSELON RS06195
gene id: 1294273:ROSELON_RS06195
uniprot id: W8RR99
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1294273:ROSELON RS12365
gene id: 1294273:ROSELON_RS12365
uniprot id: W8S459
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1294273:ROSELON RS02145
gene id: 1294273:ROSELON_RS02145
uniprot id: W8S2G8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1294273:ROSELON RS08670
gene id: 1294273:ROSELON_RS08670
uniprot id: W8SNU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1294273:ROSELON RS15845
gene id: 1294273:ROSELON_RS15845
uniprot id: W8RWF3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

1294273:ROSELON RS00370
gene id: 1294273:ROSELON_RS00370
uniprot id: W8RN48
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1294273:ROSELON RS03225
gene id: 1294273:ROSELON_RS03225
uniprot id: W8RPL3
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

1294273:ROSELON RS14125
gene id: 1294273:ROSELON_RS14125
uniprot id: W8S510
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1294273:ROSELON RS04655
gene id: 1294273:ROSELON_RS04655
uniprot id: W8RZV3
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

1294273:ROSELON RS16745
gene id: 1294273:ROSELON_RS16745
uniprot id: W8RWV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1294273:ROSELON RS08780
gene id: 1294273:ROSELON_RS08780
uniprot id: W8RSW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1294273:ROSELON RS15570
gene id: 1294273:ROSELON_RS15570
uniprot id: W8SSV0
names: Similarity
messages: Belongs to the TelA family.

1294273:ROSELON RS11135
gene id: 1294273:ROSELON_RS11135
uniprot id: W8RU05
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS07855
gene id: 1294273:ROSELON_RS07855
uniprot id: W8S1K5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1294273:ROSELON RS06065
gene id: 1294273:ROSELON_RS06065
uniprot id: W8S0K6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1294273:ROSELON RS00285
gene id: 1294273:ROSELON_RS00285
uniprot id: W8RXJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1294273:ROSELON RS14090
gene id: 1294273:ROSELON_RS14090
uniprot id: W8SRZ2
names: Similarity
messages: Belongs to the UPF0145 family.

1294273:ROSELON RS16820
gene id: 1294273:ROSELON_RS16820
uniprot id: W8RWX0
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1294273:ROSELON RS05080
gene id: 1294273:ROSELON_RS05080
uniprot id: W8S036
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ChlB/BchB/BchZ family.
messages: Chlorophyllide reductase is composed of three subunits; BchX, BchY and BchZ. Forms a heterodimer of one BchY and one BchZ subunit.
messages: Converts chlorophylls (Chl) into bacteriochlorophylls (BChl) by reducing ring B of the tetrapyrrole.

1294273:ROSELON RS05785
gene id: 1294273:ROSELON_RS05785
uniprot id: W8RRB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1294273:ROSELON RS16070
gene id: 1294273:ROSELON_RS16070
uniprot id: W8RWW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1294273:ROSELON RS04980
gene id: 1294273:ROSELON_RS04980
uniprot id: W8S018
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1294273:ROSELON RS05645
gene id: 1294273:ROSELON_RS05645
uniprot id: W8SM32
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1294273:ROSELON RS11130
gene id: 1294273:ROSELON_RS11130
uniprot id: W8RU17
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS09330
gene id: 1294273:ROSELON_RS09330
uniprot id: W8RT04
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1294273:ROSELON RS07535
gene id: 1294273:ROSELON_RS07535
uniprot id: W8RS49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1294273:ROSELON RS01075
gene id: 1294273:ROSELON_RS01075
uniprot id: W8RXX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1294273:ROSELON RS01610
gene id: 1294273:ROSELON_RS01610
uniprot id: W8RP45
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS02650
gene id: 1294273:ROSELON_RS02650
uniprot id: W8RYS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1294273:ROSELON RS06715
gene id: 1294273:ROSELON_RS06715
uniprot id: W8S0X5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1294273:ROSELON RS07335
gene id: 1294273:ROSELON_RS07335
uniprot id: W8S573
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1294273:ROSELON RS00650
gene id: 1294273:ROSELON_RS00650
uniprot id: W8S1I8
names: Subunit
messages: Homodimer.

1294273:ROSELON RS04105
gene id: 1294273:ROSELON_RS04105
uniprot id: W8RQ36
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1294273:ROSELON RS08090
gene id: 1294273:ROSELON_RS08090
uniprot id: W8RSE2
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

1294273:ROSELON RS07245
gene id: 1294273:ROSELON_RS07245
uniprot id: W8S1B3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1294273:ROSELON RS13410
gene id: 1294273:ROSELON_RS13410
uniprot id: W8S4N0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1294273:ROSELON RS06775
gene id: 1294273:ROSELON_RS06775
uniprot id: W8RRM1
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1294273:ROSELON RS06835
gene id: 1294273:ROSELON_RS06835
uniprot id: W8S101
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

1294273:ROSELON RS03780
gene id: 1294273:ROSELON_RS03780
uniprot id: W8S382
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1294273:ROSELON RS13540
gene id: 1294273:ROSELON_RS13540
uniprot id: W8SRM9
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1294273:ROSELON RS11720
gene id: 1294273:ROSELON_RS11720
uniprot id: W8S3Q0
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1294273:ROSELON RS10885
gene id: 1294273:ROSELON_RS10885
uniprot id: W8RTW3
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS05845
gene id: 1294273:ROSELON_RS05845
uniprot id: W8S4B9
names: Similarity
messages: Belongs to the transglycosylase Slt family.
messages: Belongs to the virb1 family.

1294273:ROSELON RS09505
gene id: 1294273:ROSELON_RS09505
uniprot id: W8RT93
names: Subcellular Location Annotation
messages: Cell inner membrane

1294273:ROSELON RS16170
gene id: 1294273:ROSELON_RS16170
uniprot id: W8RWK9
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1294273:ROSELON RS06335
gene id: 1294273:ROSELON_RS06335
uniprot id: W8S4K0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1294273:ROSELON RS05100
gene id: 1294273:ROSELON_RS05100
uniprot id: W8S3Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reaction center PufL/M/PsbA/D family.
messages: Cellular chromatophore membrane
messages: Membrane
messages: The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis.

1294273:ROSELON RS08185
gene id: 1294273:ROSELON_RS08185
uniprot id: W8RSF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1294273:ROSELON RS01595
gene id: 1294273:ROSELON_RS01595
uniprot id: W8SJV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.
messages: Belongs to the antenna complex beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The core complex is formed by different alpha and beta chains, binding bacteriochlorophyll molecules, and arranged most probably in tetrameric structures disposed around the reaction center. The non-pigmented gamma chains may constitute additional components.

1294273:ROSELON RS14330
gene id: 1294273:ROSELON_RS14330
uniprot id: W8S544
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1294273:ROSELON RS15265
gene id: 1294273:ROSELON_RS15265
uniprot id: W8S5P1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1294273:ROSELON RS14280
gene id: 1294273:ROSELON_RS14280
uniprot id: W8S534
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1294273:ROSELON RS04975
gene id: 1294273:ROSELON_RS04975
uniprot id: W8S3W5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1294273:ROSELON RS10320
gene id: 1294273:ROSELON_RS10320
uniprot id: W8S2X9
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1294273:ROSELON RS13450
gene id: 1294273:ROSELON_RS13450
uniprot id: W8SRL5
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

1294273:ROSELON RS12785
gene id: 1294273:ROSELON_RS12785
uniprot id: W8RUW6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1294273:ROSELON RS12425
gene id: 1294273:ROSELON_RS12425
uniprot id: W8RUU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1294273:ROSELON RS05675
gene id: 1294273:ROSELON_RS05675
uniprot id: W8S486
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1294273:ROSELON RS06010
gene id: 1294273:ROSELON_RS06010
uniprot id: W8SM99
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1294273:ROSELON RS13985
gene id: 1294273:ROSELON_RS13985
uniprot id: W8RVP6
names: Caution
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1294273:ROSELON RS08035
gene id: 1294273:ROSELON_RS08035
uniprot id: W8RSI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

1294273:ROSELON RS16565
gene id: 1294273:ROSELON_RS16565
uniprot id: W8RWR9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1294273:ROSELON RS05040
gene id: 1294273:ROSELON_RS05040
uniprot id: W8RQQ0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1294273:ROSELON RS05820
gene id: 1294273:ROSELON_RS05820
uniprot id: W8S4B6
names: Similarity
messages: Belongs to the TPP enzyme family.

1294273:ROSELON RS13370
gene id: 1294273:ROSELON_RS13370
uniprot id: W8SRK0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1294273:ROSELON RS14605
gene id: 1294273:ROSELON_RS14605
uniprot id: W8RVW7
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1294273:ROSELON RS09360
gene id: 1294273:ROSELON_RS09360
uniprot id: W8SP93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1294273:ROSELON RS11920
gene id: 1294273:ROSELON_RS11920
uniprot id: W8S3T3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1294273:ROSELON RS16290
gene id: 1294273:ROSELON_RS16290
uniprot id: W8RX10
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS12440
gene id: 1294273:ROSELON_RS12440
uniprot id: W8S470
names: Subcellular Location Annotation
messages: Secreted

1294273:ROSELON RS16845
gene id: 1294273:ROSELON_RS16845
uniprot id: W8RWX6
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1294273:ROSELON RS12980
gene id: 1294273:ROSELON_RS12980
uniprot id: W8RUZ8
names: Function
messages: Multidrug efflux pump.

1294273:ROSELON RS06085
gene id: 1294273:ROSELON_RS06085
uniprot id: W8S4G3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1294273:ROSELON RS03100
gene id: 1294273:ROSELON_RS03100
uniprot id: W8S2X0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1294273:ROSELON RS02730
gene id: 1294273:ROSELON_RS02730
uniprot id: W8RPE9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1294273:ROSELON RS15840
gene id: 1294273:ROSELON_RS15840
uniprot id: W8S5Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1294273:ROSELON RS16960
gene id: 1294273:ROSELON_RS16960
uniprot id: W8S6H4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1294273:ROSELON RS15150
gene id: 1294273:ROSELON_RS15150
uniprot id: W8S971
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1294273:ROSELON RS14100
gene id: 1294273:ROSELON_RS14100
uniprot id: W8S505
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.

1294273:ROSELON RS00810
gene id: 1294273:ROSELON_RS00810
uniprot id: W8RNQ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1294273:ROSELON RS09455
gene id: 1294273:ROSELON_RS09455
uniprot id: W8RT85
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

1294273:ROSELON RS14400
gene id: 1294273:ROSELON_RS14400
uniprot id: W8S8R9
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1294273:ROSELON RS15830
gene id: 1294273:ROSELON_RS15830
uniprot id: W8ST07
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1294273:ROSELON RS09865
gene id: 1294273:ROSELON_RS09865
uniprot id: W8RTC0
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS18125
gene id: 1294273:ROSELON_RS18125
uniprot id: W8S0D4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1294273:ROSELON RS02630
gene id: 1294273:ROSELON_RS02630
uniprot id: W8RPQ4
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS07650
gene id: 1294273:ROSELON_RS07650
uniprot id: W8RS67
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

1294273:ROSELON RS00110
gene id: 1294273:ROSELON_RS00110
uniprot id: W8RN13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1294273:ROSELON RS16955
gene id: 1294273:ROSELON_RS16955
uniprot id: W8SA31
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1294273:ROSELON RS05910
gene id: 1294273:ROSELON_RS05910
uniprot id: W8SM80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1294273:ROSELON RS02685
gene id: 1294273:ROSELON_RS02685
uniprot id: W8RPE1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1294273:ROSELON RS14665
gene id: 1294273:ROSELON_RS14665
uniprot id: W8SSF3
names: Similarity
messages: Belongs to the citrate synthase family.

1294273:ROSELON RS01480
gene id: 1294273:ROSELON_RS01480
uniprot id: W8S201
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1294273:ROSELON RS12720
gene id: 1294273:ROSELON_RS12720
uniprot id: W8SR79
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1294273:ROSELON RS01500
gene id: 1294273:ROSELON_RS01500
uniprot id: W8S204
names: Subcellular Location Annotation
messages: Cell inner membrane

1294273:ROSELON RS11450
gene id: 1294273:ROSELON_RS11450
uniprot id: W8S756
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1294273:ROSELON RS00120
gene id: 1294273:ROSELON_RS00120
uniprot id: W8S1A3
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS03940
gene id: 1294273:ROSELON_RS03940
uniprot id: W8RZE5
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1294273:ROSELON RS00800
gene id: 1294273:ROSELON_RS00800
uniprot id: W8S1M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1294273:ROSELON RS05180
gene id: 1294273:ROSELON_RS05180
uniprot id: W8RQS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PucC family.
messages: Membrane

1294273:ROSELON RS08760
gene id: 1294273:ROSELON_RS08760
uniprot id: W8RSQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1294273:ROSELON RS12305
gene id: 1294273:ROSELON_RS12305
uniprot id: W8S7Q8
names: Similarity
messages: Belongs to the pirin family.

1294273:ROSELON RS09140
gene id: 1294273:ROSELON_RS09140
uniprot id: W8SP50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1294273:ROSELON RS09710
gene id: 1294273:ROSELON_RS09710
uniprot id: W8RTA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1294273:ROSELON RS10070
gene id: 1294273:ROSELON_RS10070
uniprot id: W8RTI9
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1294273:ROSELON RS00255
gene id: 1294273:ROSELON_RS00255
uniprot id: W8S1C7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

1294273:ROSELON RS07410
gene id: 1294273:ROSELON_RS07410
uniprot id: W8S587
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1294273:ROSELON RS09715
gene id: 1294273:ROSELON_RS09715
uniprot id: W8SPJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1294273:ROSELON RS12590
gene id: 1294273:ROSELON_RS12590
uniprot id: W8SR58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1294273:ROSELON RS02395
gene id: 1294273:ROSELON_RS02395
uniprot id: W8S2K2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1294273:ROSELON RS10095
gene id: 1294273:ROSELON_RS10095
uniprot id: W8RTF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1294273:ROSELON RS11365
gene id: 1294273:ROSELON_RS11365
uniprot id: W8RU54
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1294273:ROSELON RS06205
gene id: 1294273:ROSELON_RS06205
uniprot id: W8S4I2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1294273:ROSELON RS00785
gene id: 1294273:ROSELON_RS00785
uniprot id: W8RNP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1294273:ROSELON RS10580
gene id: 1294273:ROSELON_RS10580
uniprot id: W8RTQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

1294273:ROSELON RS07220
gene id: 1294273:ROSELON_RS07220
uniprot id: W8S1B0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1294273:ROSELON RS12730
gene id: 1294273:ROSELON_RS12730
uniprot id: W8S4B5
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS00875
gene id: 1294273:ROSELON_RS00875
uniprot id: W8RNR6
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.

1294273:ROSELON RS00070
gene id: 1294273:ROSELON_RS00070
uniprot id: W8S197
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1294273:ROSELON RS10465
gene id: 1294273:ROSELON_RS10465
uniprot id: W8S2Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1294273:ROSELON RS09125
gene id: 1294273:ROSELON_RS09125
uniprot id: W8S277
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1294273:ROSELON RS13890
gene id: 1294273:ROSELON_RS13890
uniprot id: W8SRV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1294273:ROSELON RS15765
gene id: 1294273:ROSELON_RS15765
uniprot id: W8S5Y3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

1294273:ROSELON RS16205
gene id: 1294273:ROSELON_RS16205
uniprot id: W8ST84
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

1294273:ROSELON RS10175
gene id: 1294273:ROSELON_RS10175
uniprot id: W8RTK9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1294273:ROSELON RS11550
gene id: 1294273:ROSELON_RS11550
uniprot id: W8S3L7
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1294273:ROSELON RS14440
gene id: 1294273:ROSELON_RS14440
uniprot id: W8RVZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1294273:ROSELON RS08180
gene id: 1294273:ROSELON_RS08180
uniprot id: W8RSL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1294273:ROSELON RS11615
gene id: 1294273:ROSELON_RS11615
uniprot id: W8S7A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1294273:ROSELON RS07935
gene id: 1294273:ROSELON_RS07935
uniprot id: W8SNF7
names: Subcellular Location Annotation
messages: Cell inner membrane

1294273:ROSELON RS15025
gene id: 1294273:ROSELON_RS15025
uniprot id: W8S954
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1294273:ROSELON RS13790
gene id: 1294273:ROSELON_RS13790
uniprot id: W8SRT1
names: Similarity
messages: Belongs to the peptidase S33 family.

1294273:ROSELON RS11370
gene id: 1294273:ROSELON_RS11370
uniprot id: W8SQD8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1294273:ROSELON RS09235
gene id: 1294273:ROSELON_RS09235
uniprot id: W8RT50
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1294273:ROSELON RS18580
gene id: 1294273:ROSELON_RS18580
uniprot id: W8S2D5
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS04485
gene id: 1294273:ROSELON_RS04485
uniprot id: W8RZR2
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

1294273:ROSELON RS01055
gene id: 1294273:ROSELON_RS01055
uniprot id: W8RNV0
names: Cofactor
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

1294273:ROSELON RS14935
gene id: 1294273:ROSELON_RS14935
uniprot id: W8S938
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

1294273:ROSELON RS10340
gene id: 1294273:ROSELON_RS10340
uniprot id: W8S6N5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1294273:ROSELON RS08325
gene id: 1294273:ROSELON_RS08325
uniprot id: W8RSN3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1294273:ROSELON RS08405
gene id: 1294273:ROSELON_RS08405
uniprot id: W8RSI9
names: Similarity
messages: Belongs to the GcvT family.

1294273:ROSELON RS04060
gene id: 1294273:ROSELON_RS04060
uniprot id: W8SL55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1294273:ROSELON RS11950
gene id: 1294273:ROSELON_RS11950
uniprot id: W8S3T9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1294273:ROSELON RS04660
gene id: 1294273:ROSELON_RS04660
uniprot id: W8RQP2
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

1294273:ROSELON RS10245
gene id: 1294273:ROSELON_RS10245
uniprot id: W8RTM2
names: Subcellular Location Annotation
messages: Cell inner membrane

1294273:ROSELON RS10730
gene id: 1294273:ROSELON_RS10730
uniprot id: W8S346
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1294273:ROSELON RS14820
gene id: 1294273:ROSELON_RS14820
uniprot id: W8RVZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1294273:ROSELON RS07055
gene id: 1294273:ROSELON_RS07055
uniprot id: W8SMY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1294273:ROSELON RS05430
gene id: 1294273:ROSELON_RS05430
uniprot id: W8SLY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1294273:ROSELON RS04045
gene id: 1294273:ROSELON_RS04045
uniprot id: W8RZG5
names: Similarity
messages: Belongs to the peptidase U62 family.

1294273:ROSELON RS02475
gene id: 1294273:ROSELON_RS02475
uniprot id: W8RYP9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1294273:ROSELON RS02605
gene id: 1294273:ROSELON_RS02605
uniprot id: W8RPQ0
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

1294273:ROSELON RS06230
gene id: 1294273:ROSELON_RS06230
uniprot id: W8SME3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1294273:ROSELON RS11395
gene id: 1294273:ROSELON_RS11395
uniprot id: W8SQE3
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.
messages: Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids.

1294273:ROSELON RS08865
gene id: 1294273:ROSELON_RS08865
uniprot id: W8RSY0
names: Similarity
messages: Belongs to the GSP E family.

1294273:ROSELON RS14575
gene id: 1294273:ROSELON_RS14575
uniprot id: W8S5C0
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS05055
gene id: 1294273:ROSELON_RS05055
uniprot id: W8S030
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1294273:ROSELON RS03860
gene id: 1294273:ROSELON_RS03860
uniprot id: W8S397
names: Similarity
messages: Belongs to the peptidase M16 family.

1294273:ROSELON RS06340
gene id: 1294273:ROSELON_RS06340
uniprot id: W8S0Q5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1294273:ROSELON RS04710
gene id: 1294273:ROSELON_RS04710
uniprot id: W8RQT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1294273:ROSELON RS00570
gene id: 1294273:ROSELON_RS00570
uniprot id: W8S1H5
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS00300
gene id: 1294273:ROSELON_RS00300
uniprot id: W8SJ62
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Interacts with CtaA.
messages: Membrane

1294273:ROSELON RS10375
gene id: 1294273:ROSELON_RS10375
uniprot id: W8RTN9
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

1294273:ROSELON RS16020
gene id: 1294273:ROSELON_RS16020
uniprot id: W8ST49
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS09840
gene id: 1294273:ROSELON_RS09840
uniprot id: W8RTB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1294273:ROSELON RS09810
gene id: 1294273:ROSELON_RS09810
uniprot id: W8RTB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1294273:ROSELON RS08700
gene id: 1294273:ROSELON_RS08700
uniprot id: W8S5V0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1294273:ROSELON RS13860
gene id: 1294273:ROSELON_RS13860
uniprot id: W8RVM1
names: Similarity
messages: Belongs to the UPF0178 family.

1294273:ROSELON RS10450
gene id: 1294273:ROSELON_RS10450
uniprot id: W8RTM5
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

1294273:ROSELON RS05980
gene id: 1294273:ROSELON_RS05980
uniprot id: W8RRF3
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the WrbA family.
messages: Binds 1 FMN per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1294273:ROSELON RS00700
gene id: 1294273:ROSELON_RS00700
uniprot id: W8RNM6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1294273:ROSELON RS15250
gene id: 1294273:ROSELON_RS15250
uniprot id: W8RWG7
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS04595
gene id: 1294273:ROSELON_RS04595
uniprot id: W8RQE2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1294273:ROSELON RS07190
gene id: 1294273:ROSELON_RS07190
uniprot id: W8S549
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1294273:ROSELON RS14845
gene id: 1294273:ROSELON_RS14845
uniprot id: W8RW02
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS00410
gene id: 1294273:ROSELON_RS00410
uniprot id: W8RXL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1294273:ROSELON RS09470
gene id: 1294273:ROSELON_RS09470
uniprot id: W8S688
names: Similarity
messages: Belongs to the GARS family.

1294273:ROSELON RS14250
gene id: 1294273:ROSELON_RS14250
uniprot id: W8S8N5
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS14955
gene id: 1294273:ROSELON_RS14955
uniprot id: W8SSJ5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1294273:ROSELON RS14775
gene id: 1294273:ROSELON_RS14775
uniprot id: W8RVZ0
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1294273:ROSELON RS06825
gene id: 1294273:ROSELON_RS06825
uniprot id: W8SMS6
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1294273:ROSELON RS01255
gene id: 1294273:ROSELON_RS01255
uniprot id: W8S1W2
names: Similarity
messages: Belongs to the CFA/CMAS family.

1294273:ROSELON RS00310
gene id: 1294273:ROSELON_RS00310
uniprot id: W8RXJ4
names: Similarity
messages: Belongs to the peptidase U62 family.

1294273:ROSELON RS13880
gene id: 1294273:ROSELON_RS13880
uniprot id: W8RVE9
names: Similarity
messages: Belongs to the allantoicase family.

1294273:ROSELON RS01850
gene id: 1294273:ROSELON_RS01850
uniprot id: W8RYC6
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1294273:ROSELON RS08740
gene id: 1294273:ROSELON_RS08740
uniprot id: W8SNW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1294273:ROSELON RS13960
gene id: 1294273:ROSELON_RS13960
uniprot id: W8RVP0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1294273:ROSELON RS14485
gene id: 1294273:ROSELON_RS14485
uniprot id: W8RVR8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1294273:ROSELON RS16500
gene id: 1294273:ROSELON_RS16500
uniprot id: W8STC5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

1294273:ROSELON RS03495
gene id: 1294273:ROSELON_RS03495
uniprot id: W8RZ62
names: Similarity
messages: Belongs to the glutamate synthase family.

1294273:ROSELON RS03885
gene id: 1294273:ROSELON_RS03885
uniprot id: W8S3A2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1294273:ROSELON RS13835
gene id: 1294273:ROSELON_RS13835
uniprot id: W8SRU1
names: Similarity
messages: Belongs to the BolA/IbaG family.

1294273:ROSELON RS06305
gene id: 1294273:ROSELON_RS06305
uniprot id: W8SMF6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1294273:ROSELON RS00565
gene id: 1294273:ROSELON_RS00565
uniprot id: W8SJA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1294273:ROSELON RS07575
gene id: 1294273:ROSELON_RS07575
uniprot id: W8S5B2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1294273:ROSELON RS12825
gene id: 1294273:ROSELON_RS12825
uniprot id: W8S7Y6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1294273:ROSELON RS12495
gene id: 1294273:ROSELON_RS12495
uniprot id: W8S7T6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1294273:ROSELON RS09145
gene id: 1294273:ROSELON_RS09145
uniprot id: W8S629
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1294273:ROSELON RS08505
gene id: 1294273:ROSELON_RS08505
uniprot id: W8RSK5
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1294273:ROSELON RS13650
gene id: 1294273:ROSELON_RS13650
uniprot id: W8S8C5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1294273:ROSELON RS07155
gene id: 1294273:ROSELON_RS07155
uniprot id: W8RRY8
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1294273:ROSELON RS08840
gene id: 1294273:ROSELON_RS08840
uniprot id: W8RSX6
names: Similarity
messages: Belongs to the peptidase A24 family.

1294273:ROSELON RS04410
gene id: 1294273:ROSELON_RS04410
uniprot id: W8SLC2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1294273:ROSELON RS10035
gene id: 1294273:ROSELON_RS10035
uniprot id: W8S6J5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1294273:ROSELON RS05205
gene id: 1294273:ROSELON_RS05205
uniprot id: W8SLV0
names: Function
names: Similarity
messages: Belongs to the AcsF family.
messages: Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME).

1294273:ROSELON RS08115
gene id: 1294273:ROSELON_RS08115
uniprot id: W8SNI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1294273:ROSELON RS00655
gene id: 1294273:ROSELON_RS00655
uniprot id: W8RXQ1
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

1294273:ROSELON RS01670
gene id: 1294273:ROSELON_RS01670
uniprot id: W8S235
names: Function
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.

1294273:ROSELON RS08860
gene id: 1294273:ROSELON_RS08860
uniprot id: W8S223
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS04270
gene id: 1294273:ROSELON_RS04270
uniprot id: W8RQG6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

1294273:ROSELON RS01680
gene id: 1294273:ROSELON_RS01680
uniprot id: W8RP56
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1294273:ROSELON RS04570
gene id: 1294273:ROSELON_RS04570
uniprot id: W8RQD5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1294273:ROSELON RS08315
gene id: 1294273:ROSELON_RS08315
uniprot id: W8S5M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0283 family.
messages: Cell inner membrane
messages: Membrane

1294273:ROSELON RS13845
gene id: 1294273:ROSELON_RS13845
uniprot id: W8S4V8
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

1294273:ROSELON RS12885
gene id: 1294273:ROSELON_RS12885
uniprot id: W8RV36
names: Similarity
messages: Belongs to the CFA/CMAS family.

1294273:ROSELON RS14120
gene id: 1294273:ROSELON_RS14120
uniprot id: W8S8K7
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1294273:ROSELON RS05420
gene id: 1294273:ROSELON_RS05420
uniprot id: W8RR43
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1294273:ROSELON RS16660
gene id: 1294273:ROSELON_RS16660
uniprot id: W8S6C8
names: Similarity
messages: Belongs to the glutamate synthase family.

1294273:ROSELON RS03985
gene id: 1294273:ROSELON_RS03985
uniprot id: W8SL41
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1294273:ROSELON RS16010
gene id: 1294273:ROSELON_RS16010
uniprot id: W8RWI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1294273:ROSELON RS06655
gene id: 1294273:ROSELON_RS06655
uniprot id: W8S4Q7
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1294273:ROSELON RS04810
gene id: 1294273:ROSELON_RS04810
uniprot id: W8RQL4
names: Subcellular Location Annotation
messages: Cell outer membrane

1294273:ROSELON RS07390
gene id: 1294273:ROSELON_RS07390
uniprot id: W8S1D5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1294273:ROSELON RS13110
gene id: 1294273:ROSELON_RS13110
uniprot id: W8S836
names: Similarity
messages: Belongs to the Dps family.

1294273:ROSELON RS00405
gene id: 1294273:ROSELON_RS00405
uniprot id: W8S1F0
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1294273:ROSELON RS07695
gene id: 1294273:ROSELON_RS07695
uniprot id: W8RS75
names: Similarity
messages: Belongs to the PhoH family.

1294273:ROSELON RS13070
gene id: 1294273:ROSELON_RS13070
uniprot id: W8RV16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1294273:ROSELON RS01080
gene id: 1294273:ROSELON_RS01080
uniprot id: W8RNG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1294273:ROSELON RS11690
gene id: 1294273:ROSELON_RS11690
uniprot id: W8S7B6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1294273:ROSELON RS09795
gene id: 1294273:ROSELON_RS09795
uniprot id: W8S6G7
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1294273:ROSELON RS05160
gene id: 1294273:ROSELON_RS05160
uniprot id: W8RQR6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ChlB/BchB/BchZ family.
messages: Binds 1 [4Fe-4S] cluster per heterodimer. The cluster is bound at the heterodimer interface by residues from both subunits.
messages: Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex.
messages: Protochlorophyllide reductase is composed of three subunits; BchL, BchN and BchB. Forms a heterotetramer of two BchB and two BchN subunits.

1294273:ROSELON RS15595
gene id: 1294273:ROSELON_RS15595
uniprot id: W8SSV5
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1294273:ROSELON RS14825
gene id: 1294273:ROSELON_RS14825
uniprot id: W8RWA5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1294273:ROSELON RS16975
gene id: 1294273:ROSELON_RS16975
uniprot id: W8SA39
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1294273:ROSELON RS01835
gene id: 1294273:ROSELON_RS01835
uniprot id: W8RNW9
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1294273:ROSELON RS12950
gene id: 1294273:ROSELON_RS12950
uniprot id: W8S806
names: Similarity
messages: Belongs to the SHMT family.

1294273:ROSELON RS09685
gene id: 1294273:ROSELON_RS09685
uniprot id: W8RT97
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1294273:ROSELON RS05580
gene id: 1294273:ROSELON_RS05580
uniprot id: W8S0C2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1294273:ROSELON RS03290
gene id: 1294273:ROSELON_RS03290
uniprot id: W8RZ30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

1294273:ROSELON RS15105
gene id: 1294273:ROSELON_RS15105
uniprot id: W8RWE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1294273:ROSELON RS05850
gene id: 1294273:ROSELON_RS05850
uniprot id: W8RRC6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1294273:ROSELON RS08450
gene id: 1294273:ROSELON_RS08450
uniprot id: W8RSQ7
names: Subcellular Location Annotation
messages: Cell membrane

1294273:ROSELON RS01150
gene id: 1294273:ROSELON_RS01150
uniprot id: W8RNX0
names: Subcellular Location Annotation
messages: Cytoplasm

1294273:ROSELON RS14220
gene id: 1294273:ROSELON_RS14220
uniprot id: W8S8N0
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1294273:ROSELON RS04995
gene id: 1294273:ROSELON_RS04995
uniprot id: W8SLR8
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

1294273:ROSELON RS13995
gene id: 1294273:ROSELON_RS13995
uniprot id: W8S8I2
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1294273:ROSELON RS03745
gene id: 1294273:ROSELON_RS03745
uniprot id: W8RPV9
names: Similarity
messages: Belongs to the YkuD family.

1294273:ROSELON RS06100
gene id: 1294273:ROSELON_RS06100
uniprot id: W8SMC0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1294273:ROSELON RS13495
gene id: 1294273:ROSELON_RS13495
uniprot id: W8S4P2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1294273:ROSELON RS00455
gene id: 1294273:ROSELON_RS00455
uniprot id: W8SJ87
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1294273:ROSELON RS15295
gene id: 1294273:ROSELON_RS15295
uniprot id: W8SSQ3
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

1294273:ROSELON RS04615
gene id: 1294273:ROSELON_RS04615
uniprot id: W8RQN2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1294273:ROSELON RS04420
gene id: 1294273:ROSELON_RS04420
uniprot id: W8RZP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1294273:ROSELON RS14410
gene id: 1294273:ROSELON_RS14410
uniprot id: W8RVQ5
names: Function
messages: Multidrug efflux pump.

1294273:ROSELON RS02085
gene id: 1294273:ROSELON_RS02085
uniprot id: W8RP19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1294273:ROSELON RS14230
gene id: 1294273:ROSELON_RS14230
uniprot id: W8S526
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1294273:ROSELON RS05770
gene id: 1294273:ROSELON_RS05770
uniprot id: W8SM52
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1294273:ROSELON RS15875
gene id: 1294273:ROSELON_RS15875
uniprot id: W8RWS7
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1294273:ROSELON RS04625
gene id: 1294273:ROSELON_RS04625
uniprot id: W8SLH0
names: Similarity
messages: Belongs to the YkuD family.

1294273:ROSELON RS14680
gene id: 1294273:ROSELON_RS14680
uniprot id: W8S5D3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

1294273:ROSELON RS06970
gene id: 1294273:ROSELON_RS06970
uniprot id: W8RRX7
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1294273:ROSELON RS04550
gene id: 1294273:ROSELON_RS04550
uniprot id: W8SLF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1294273:ROSELON RS15525
gene id: 1294273:ROSELON_RS15525
uniprot id: W8SSU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

1294273:ROSELON RS05740
gene id: 1294273:ROSELON_RS05740
uniprot id: W8SM47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1294273:ROSELON RS03620
gene id: 1294273:ROSELON_RS03620
uniprot id: W8RQ52
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

1294273:ROSELON RS08920
gene id: 1294273:ROSELON_RS08920
uniprot id: W8RST1
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1294273:ROSELON RS05620
gene id: 1294273:ROSELON_RS05620
uniprot id: W8SM27
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS12500
gene id: 1294273:ROSELON_RS12500
uniprot id: W8S476
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1294273:ROSELON RS05880
gene id: 1294273:ROSELON_RS05880
uniprot id: W8RR37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1294273:ROSELON RS13145
gene id: 1294273:ROSELON_RS13145
uniprot id: W8RV31
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS07850
gene id: 1294273:ROSELON_RS07850
uniprot id: W8S5E7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1294273:ROSELON RS04030
gene id: 1294273:ROSELON_RS04030
uniprot id: W8RQ18
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1294273:ROSELON RS01110
gene id: 1294273:ROSELON_RS01110
uniprot id: W8RNH0
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1294273:ROSELON RS03870
gene id: 1294273:ROSELON_RS03870
uniprot id: W8RQ96
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1294273:ROSELON RS06915
gene id: 1294273:ROSELON_RS06915
uniprot id: W8RRQ0
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1294273:ROSELON RS11035
gene id: 1294273:ROSELON_RS11035
uniprot id: W8SQ64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

1294273:ROSELON RS09085
gene id: 1294273:ROSELON_RS09085
uniprot id: W8RT23
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1294273:ROSELON RS15045
gene id: 1294273:ROSELON_RS15045
uniprot id: W8SSL1
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1294273:ROSELON RS13685
gene id: 1294273:ROSELON_RS13685
uniprot id: W8RVB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1294273:ROSELON RS16475
gene id: 1294273:ROSELON_RS16475
uniprot id: W8RWQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1294273:ROSELON RS07305
gene id: 1294273:ROSELON_RS07305
uniprot id: W8SN63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1294273:ROSELON RS05215
gene id: 1294273:ROSELON_RS05215
uniprot id: W8S060
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1294273:ROSELON RS11985
gene id: 1294273:ROSELON_RS11985
uniprot id: W8RUJ6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1294273:ROSELON RS07345
gene id: 1294273:ROSELON_RS07345
uniprot id: W8RS79
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1294273:ROSELON RS15345
gene id: 1294273:ROSELON_RS15345
uniprot id: W8RWI2
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1294273:ROSELON RS08235
gene id: 1294273:ROSELON_RS08235
uniprot id: W8RSG4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1294273:ROSELON RS14580
gene id: 1294273:ROSELON_RS14580
uniprot id: W8RVW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1294273:ROSELON RS07565
gene id: 1294273:ROSELON_RS07565
uniprot id: W8RS54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1294273:ROSELON RS12210
gene id: 1294273:ROSELON_RS12210
uniprot id: W8RUR5
names: Function
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Has multiple catalytic activities. Apart from catalyzing the oxidation of (+)-tartrate to oxaloglycolate, also converts meso-tartrate to D-glycerate and catalyzes the oxidative decarboxylation of D-malate to pyruvate.

1294273:ROSELON RS09570
gene id: 1294273:ROSELON_RS09570
uniprot id: W8S6A5
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1294273:ROSELON RS07570
gene id: 1294273:ROSELON_RS07570
uniprot id: W8SNA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1294273:ROSELON RS01260
gene id: 1294273:ROSELON_RS01260
uniprot id: W8RNZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1294273:ROSELON RS13040
gene id: 1294273:ROSELON_RS13040
uniprot id: W8S4G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

1294273:ROSELON RS12330
gene id: 1294273:ROSELON_RS12330
uniprot id: W8RUT4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1294273:ROSELON RS14135
gene id: 1294273:ROSELON_RS14135
uniprot id: W8RVS5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1294273:ROSELON RS07225
gene id: 1294273:ROSELON_RS07225
uniprot id: W8RS58
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1294273:ROSELON RS10795
gene id: 1294273:ROSELON_RS10795
uniprot id: W8S6V1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1294273:ROSELON RS08030
gene id: 1294273:ROSELON_RS08030
uniprot id: W8S1N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

1294273:ROSELON RS08755
gene id: 1294273:ROSELON_RS08755
uniprot id: W8RSW0
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1294273:ROSELON RS12545
gene id: 1294273:ROSELON_RS12545
uniprot id: W8RUW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1294273:ROSELON RS04290
gene id: 1294273:ROSELON_RS04290
uniprot id: W8RZL2
names: Similarity
messages: Belongs to the YggT family.

1294273:ROSELON RS06280
gene id: 1294273:ROSELON_RS06280
uniprot id: W8SMF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

1294273:ROSELON RS00135
gene id: 1294273:ROSELON_RS00135
uniprot id: W8RN17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1294273:ROSELON RS09575
gene id: 1294273:ROSELON_RS09575
uniprot id: W8S2G0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1294273:ROSELON RS10140
gene id: 1294273:ROSELON_RS10140
uniprot id: W8S6K6
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1294273:ROSELON RS15600
gene id: 1294273:ROSELON_RS15600
uniprot id: W8S9D9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1294273:ROSELON RS16995
gene id: 1294273:ROSELON_RS16995
uniprot id: W8STN4
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1294273:ROSELON RS13105
gene id: 1294273:ROSELON_RS13105
uniprot id: W8SRF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

1294273:ROSELON RS04910
gene id: 1294273:ROSELON_RS04910
uniprot id: W8S010
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1294273:ROSELON RS07810
gene id: 1294273:ROSELON_RS07810
uniprot id: W8RSF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1294273:ROSELON RS03485
gene id: 1294273:ROSELON_RS03485
uniprot id: W8SKV2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

1294273:ROSELON RS06895
gene id: 1294273:ROSELON_RS06895
uniprot id: W8RRP6
names: Similarity
messages: Belongs to the proline racemase family.

1294273:ROSELON RS15280
gene id: 1294273:ROSELON_RS15280
uniprot id: W8S988
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1294273:ROSELON RS12070
gene id: 1294273:ROSELON_RS12070
uniprot id: W8S3Z1
names: Function
names: Similarity
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: May be required for disulfide bond formation in some proteins.

1294273:ROSELON RS11235
gene id: 1294273:ROSELON_RS11235
uniprot id: W8RU36
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1294273:ROSELON RS06685
gene id: 1294273:ROSELON_RS06685
uniprot id: W8S0X0
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1294273:ROSELON RS15120
gene id: 1294273:ROSELON_RS15120
uniprot id: W8S5L9
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1294273:ROSELON RS10845
gene id: 1294273:ROSELON_RS10845
uniprot id: W8SQ26
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

1294273:ROSELON RS07380
gene id: 1294273:ROSELON_RS07380
uniprot id: W8SN73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1294273:ROSELON RS00520
gene id: 1294273:ROSELON_RS00520
uniprot id: W8RNJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.

1294273:ROSELON RS09985
gene id: 1294273:ROSELON_RS09985
uniprot id: W8SPN8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1294273:ROSELON RS07060
gene id: 1294273:ROSELON_RS07060
uniprot id: W8S4Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1294273:ROSELON RS12755
gene id: 1294273:ROSELON_RS12755
uniprot id: W8S4C1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1294273:ROSELON RS05115
gene id: 1294273:ROSELON_RS05115
uniprot id: W8RQR0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1294273:ROSELON RS11155
gene id: 1294273:ROSELON_RS11155
uniprot id: W8RU22
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1294273:ROSELON RS04425
gene id: 1294273:ROSELON_RS04425
uniprot id: W8RQJ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1294273:ROSELON RS04920
gene id: 1294273:ROSELON_RS04920
uniprot id: W8SLQ7
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1294273:ROSELON RS08815
gene id: 1294273:ROSELON_RS08815
uniprot id: W8SNY0
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1294273:ROSELON RS11775
gene id: 1294273:ROSELON_RS11775
uniprot id: W8RUF5
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1294273:ROSELON RS13665
gene id: 1294273:ROSELON_RS13665
uniprot id: W8RVH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1294273:ROSELON RS05010
gene id: 1294273:ROSELON_RS05010
uniprot id: W8RQY2
names: Similarity
messages: Belongs to the Tim44 family.

1294273:ROSELON RS09885
gene id: 1294273:ROSELON_RS09885
uniprot id: W8RTG3
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1294273:ROSELON RS04725
gene id: 1294273:ROSELON_RS04725
uniprot id: W8S3T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1294273:ROSELON RS14165
gene id: 1294273:ROSELON_RS14165
uniprot id: W8S8M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1294273:ROSELON RS04565
gene id: 1294273:ROSELON_RS04565
uniprot id: W8RQM1
names: Similarity
messages: Belongs to the UPF0758 family.

1294273:ROSELON RS01950
gene id: 1294273:ROSELON_RS01950
uniprot id: W8RYE9
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS14940
gene id: 1294273:ROSELON_RS14940
uniprot id: W8S5I6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1294273:ROSELON RS01310
gene id: 1294273:ROSELON_RS01310
uniprot id: W8RNK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1294273:ROSELON RS15555
gene id: 1294273:ROSELON_RS15555
uniprot id: W8S5U7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

1294273:ROSELON RS11200
gene id: 1294273:ROSELON_RS11200
uniprot id: W8RU28
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1294273:ROSELON RS11175
gene id: 1294273:ROSELON_RS11175
uniprot id: W8S3C8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1294273:ROSELON RS11570
gene id: 1294273:ROSELON_RS11570
uniprot id: W8S789
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1294273:ROSELON RS03925
gene id: 1294273:ROSELON_RS03925
uniprot id: W8RPZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

1294273:ROSELON RS07470
gene id: 1294273:ROSELON_RS07470
uniprot id: W8SN87
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

1294273:ROSELON RS13675
gene id: 1294273:ROSELON_RS13675
uniprot id: W8S8C9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1294273:ROSELON RS14415
gene id: 1294273:ROSELON_RS14415
uniprot id: W8RVZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family.
messages: Cell membrane
messages: Membrane

1294273:ROSELON RS14780
gene id: 1294273:ROSELON_RS14780
uniprot id: W8RW96
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

1294273:ROSELON RS03590
gene id: 1294273:ROSELON_RS03590
uniprot id: W8RZ81
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS00935
gene id: 1294273:ROSELON_RS00935
uniprot id: W8RND7
names: Similarity
messages: Belongs to the GST superfamily.

1294273:ROSELON RS11490
gene id: 1294273:ROSELON_RS11490
uniprot id: W8S769
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS13595
gene id: 1294273:ROSELON_RS13595
uniprot id: W8S8B8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1294273:ROSELON RS15055
gene id: 1294273:ROSELON_RS15055
uniprot id: W8RW31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiV subfamily.
messages: Forms an heterodimer with UbiU.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiU, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

1294273:ROSELON RS01020
gene id: 1294273:ROSELON_RS01020
uniprot id: W8S1R6
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1294273:ROSELON RS08645
gene id: 1294273:ROSELON_RS08645
uniprot id: W8SNU0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1294273:ROSELON RS02300
gene id: 1294273:ROSELON_RS02300
uniprot id: W8S2I8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1294273:ROSELON RS13605
gene id: 1294273:ROSELON_RS13605
uniprot id: W8RVA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1294273:ROSELON RS12650
gene id: 1294273:ROSELON_RS12650
uniprot id: W8SR69
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

1294273:ROSELON RS07665
gene id: 1294273:ROSELON_RS07665
uniprot id: W8S1H4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1294273:ROSELON RS02705
gene id: 1294273:ROSELON_RS02705
uniprot id: W8RPE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1294273:ROSELON RS09215
gene id: 1294273:ROSELON_RS09215
uniprot id: W8RSY1
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS03765
gene id: 1294273:ROSELON_RS03765
uniprot id: W8RZB2
names: Subcellular Location Annotation
messages: chloroplast

1294273:ROSELON RS05800
gene id: 1294273:ROSELON_RS05800
uniprot id: W8S4B0
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS00675
gene id: 1294273:ROSELON_RS00675
uniprot id: W8S1J4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

1294273:ROSELON RS05455
gene id: 1294273:ROSELON_RS05455
uniprot id: W8S443
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1294273:ROSELON RS07490
gene id: 1294273:ROSELON_RS07490
uniprot id: W8RS41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

1294273:ROSELON RS17030
gene id: 1294273:ROSELON_RS17030
uniprot id: W8S6I6
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1294273:ROSELON RS04905
gene id: 1294273:ROSELON_RS04905
uniprot id: W8S3V6
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1294273:ROSELON RS09020
gene id: 1294273:ROSELON_RS09020
uniprot id: W8RSU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1294273:ROSELON RS07370
gene id: 1294273:ROSELON_RS07370
uniprot id: W8RS82
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1294273:ROSELON RS00495
gene id: 1294273:ROSELON_RS00495
uniprot id: W8RXM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

1294273:ROSELON RS08915
gene id: 1294273:ROSELON_RS08915
uniprot id: W8RSY8
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1294273:ROSELON RS01040
gene id: 1294273:ROSELON_RS01040
uniprot id: W8SJJ7
names: Subcellular Location Annotation
messages: Cytoplasm

1294273:ROSELON RS12075
gene id: 1294273:ROSELON_RS12075
uniprot id: W8RUL5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1294273:ROSELON RS08525
gene id: 1294273:ROSELON_RS08525
uniprot id: W8RSS3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1294273:ROSELON RS12935
gene id: 1294273:ROSELON_RS12935
uniprot id: W8RUZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1294273:ROSELON RS05235
gene id: 1294273:ROSELON_RS05235
uniprot id: W8S405
names: Function
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.
messages: Involved in bacteriochlorophyll biosynthesis; introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX.

1294273:ROSELON RS08105
gene id: 1294273:ROSELON_RS08105
uniprot id: W8RSJ9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.

1294273:ROSELON RS06110
gene id: 1294273:ROSELON_RS06110
uniprot id: W8S0L4
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1294273:ROSELON RS01025
gene id: 1294273:ROSELON_RS01025
uniprot id: W8RXW9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1294273:ROSELON RS01140
gene id: 1294273:ROSELON_RS01140
uniprot id: W8S1T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1294273:ROSELON RS03430
gene id: 1294273:ROSELON_RS03430
uniprot id: W8SKU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1294273:ROSELON RS05995
gene id: 1294273:ROSELON_RS05995
uniprot id: W8S0J6
names: Similarity
messages: Belongs to the histone deacetylase family.

1294273:ROSELON RS09535
gene id: 1294273:ROSELON_RS09535
uniprot id: W8RT98
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1294273:ROSELON RS12405
gene id: 1294273:ROSELON_RS12405
uniprot id: W8SR31
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1294273:ROSELON RS16740
gene id: 1294273:ROSELON_RS16740
uniprot id: W8S6D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1294273:ROSELON RS10910
gene id: 1294273:ROSELON_RS10910
uniprot id: W8RTW8
names: Subcellular Location Annotation
messages: Cell membrane

1294273:ROSELON RS16915
gene id: 1294273:ROSELON_RS16915
uniprot id: W8RWZ1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1294273:ROSELON RS09945
gene id: 1294273:ROSELON_RS09945
uniprot id: W8RTH0
names: Similarity
messages: Belongs to the universal stress protein A family.

1294273:ROSELON RS12910
gene id: 1294273:ROSELON_RS12910
uniprot id: W8RV41
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

1294273:ROSELON RS06500
gene id: 1294273:ROSELON_RS06500
uniprot id: W8RRG2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1294273:ROSELON RS09060
gene id: 1294273:ROSELON_RS09060
uniprot id: W8S262
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1294273:ROSELON RS13185
gene id: 1294273:ROSELON_RS13185
uniprot id: W8RV38
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1294273:ROSELON RS14920
gene id: 1294273:ROSELON_RS14920
uniprot id: W8RW12
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS09340
gene id: 1294273:ROSELON_RS09340
uniprot id: W8S659
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1294273:ROSELON RS12050
gene id: 1294273:ROSELON_RS12050
uniprot id: W8S3W0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1294273:ROSELON RS05285
gene id: 1294273:ROSELON_RS05285
uniprot id: W8S073
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

1294273:ROSELON RS11350
gene id: 1294273:ROSELON_RS11350
uniprot id: W8S734
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1294273:ROSELON RS13075
gene id: 1294273:ROSELON_RS13075
uniprot id: W8RV74
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS01575
gene id: 1294273:ROSELON_RS01575
uniprot id: W8S213
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1294273:ROSELON RS10700
gene id: 1294273:ROSELON_RS10700
uniprot id: W8SQ04
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1294273:ROSELON RS09970
gene id: 1294273:ROSELON_RS09970
uniprot id: W8S2R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1294273:ROSELON RS15015
gene id: 1294273:ROSELON_RS15015
uniprot id: W8RWD6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1294273:ROSELON RS07765
gene id: 1294273:ROSELON_RS07765
uniprot id: W8RS88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1294273:ROSELON RS05270
gene id: 1294273:ROSELON_RS05270
uniprot id: W8RR20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1294273:ROSELON RS17090
gene id: 1294273:ROSELON_RS17090
uniprot id: W8S6K8
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1294273:ROSELON RS08510
gene id: 1294273:ROSELON_RS08510
uniprot id: W8SNR4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-53 and Arg-56) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

1294273:ROSELON RS02315
gene id: 1294273:ROSELON_RS02315
uniprot id: W8RP86
names: Subcellular Location Annotation
messages: Cytoplasm

1294273:ROSELON RS13015
gene id: 1294273:ROSELON_RS13015
uniprot id: W8S4G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1294273:ROSELON RS12955
gene id: 1294273:ROSELON_RS12955
uniprot id: W8S4F4
names: Similarity
messages: Belongs to the universal stress protein A family.

1294273:ROSELON RS09165
gene id: 1294273:ROSELON_RS09165
uniprot id: W8SP55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1294273:ROSELON RS10215
gene id: 1294273:ROSELON_RS10215
uniprot id: W8S2W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1294273:ROSELON RS00770
gene id: 1294273:ROSELON_RS00770
uniprot id: W8RNA9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1294273:ROSELON RS04785
gene id: 1294273:ROSELON_RS04785
uniprot id: W8RQL0
names: Similarity
messages: Belongs to the Gfa family.

1294273:ROSELON RS01855
gene id: 1294273:ROSELON_RS01855
uniprot id: W8RPA1
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1294273:ROSELON RS08305
gene id: 1294273:ROSELON_RS08305
uniprot id: W8RSH4
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS06690
gene id: 1294273:ROSELON_RS06690
uniprot id: W8RRS3
names: Similarity
messages: Belongs to the UPF0246 family.

1294273:ROSELON RS14215
gene id: 1294273:ROSELON_RS14215
uniprot id: W8SS18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1294273:ROSELON RS05730
gene id: 1294273:ROSELON_RS05730
uniprot id: W8RRA3
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS10780
gene id: 1294273:ROSELON_RS10780
uniprot id: W8S358
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1294273:ROSELON RS04210
gene id: 1294273:ROSELON_RS04210
uniprot id: W8RZJ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Cell membrane
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1294273:ROSELON RS08685
gene id: 1294273:ROSELON_RS08685
uniprot id: W8RSU9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1294273:ROSELON RS14490
gene id: 1294273:ROSELON_RS14490
uniprot id: W8RW11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1294273:ROSELON RS02495
gene id: 1294273:ROSELON_RS02495
uniprot id: W8S2L8
names: Similarity
messages: Belongs to the HsdR family.

1294273:ROSELON RS07140
gene id: 1294273:ROSELON_RS07140
uniprot id: W8S530
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1294273:ROSELON RS12150
gene id: 1294273:ROSELON_RS12150
uniprot id: W8S428
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1294273:ROSELON RS04605
gene id: 1294273:ROSELON_RS04605
uniprot id: W8S3P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

1294273:ROSELON RS02965
gene id: 1294273:ROSELON_RS02965
uniprot id: W8SKM0
names: Subunit
messages: Homodimer.

1294273:ROSELON RS12205
gene id: 1294273:ROSELON_RS12205
uniprot id: W8RUN1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1294273:ROSELON RS04575
gene id: 1294273:ROSELON_RS04575
uniprot id: W8SLF6
names: Similarity
messages: Belongs to the SfsA family.

1294273:ROSELON RS13670
gene id: 1294273:ROSELON_RS13670
uniprot id: W8SRQ4
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

1294273:ROSELON RS06905
gene id: 1294273:ROSELON_RS06905
uniprot id: W8S4V9
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

1294273:ROSELON RS03015
gene id: 1294273:ROSELON_RS03015
uniprot id: W8RPI4
names: Similarity
messages: Belongs to the universal stress protein A family.

1294273:ROSELON RS13425
gene id: 1294273:ROSELON_RS13425
uniprot id: W8SRL1
names: PTM
messages: Binds 1 heme group per subunit.

1294273:ROSELON RS15180
gene id: 1294273:ROSELON_RS15180
uniprot id: W8S976
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1294273:ROSELON RS09150
gene id: 1294273:ROSELON_RS09150
uniprot id: W8S281
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1294273:ROSELON RS14305
gene id: 1294273:ROSELON_RS14305
uniprot id: W8S539
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1294273:ROSELON RS02735
gene id: 1294273:ROSELON_RS02735
uniprot id: W8SKI7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1294273:ROSELON RS05105
gene id: 1294273:ROSELON_RS05105
uniprot id: W8S039
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the reaction center PufL/M/PsbA/D family.
messages: Cellular chromatophore membrane
messages: Membrane
messages: Reaction center is composed of four bacteriochlorophylls, two bacteriopheophytins, two ubiquinones, one iron, and highly hydrophobic polypeptide chains.
messages: The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis.

1294273:ROSELON RS01285
gene id: 1294273:ROSELON_RS01285
uniprot id: W8RP00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Cytoplasm
messages: Homodimer.

1294273:ROSELON RS08600
gene id: 1294273:ROSELON_RS08600
uniprot id: W8S1Y3
names: Similarity
messages: Belongs to the IMPACT family.

1294273:ROSELON RS06720
gene id: 1294273:ROSELON_RS06720
uniprot id: W8RRS8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1294273:ROSELON RS13590
gene id: 1294273:ROSELON_RS13590
uniprot id: W8SRN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1294273:ROSELON RS05660
gene id: 1294273:ROSELON_RS05660
uniprot id: W8RR90
names: Similarity
messages: Belongs to the histone deacetylase family.

1294273:ROSELON RS04635
gene id: 1294273:ROSELON_RS04635
uniprot id: W8RZU7
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

1294273:ROSELON RS05875
gene id: 1294273:ROSELON_RS05875
uniprot id: W8RRD1
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1294273:ROSELON RS13975
gene id: 1294273:ROSELON_RS13975
uniprot id: W8S4Y3
names: Similarity
messages: Belongs to the YkuD family.

1294273:ROSELON RS06090
gene id: 1294273:ROSELON_RS06090
uniprot id: W8S0L1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1294273:ROSELON RS00925
gene id: 1294273:ROSELON_RS00925
uniprot id: W8RXV3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1294273:ROSELON RS00590
gene id: 1294273:ROSELON_RS00590
uniprot id: W8SJB0
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1294273:ROSELON RS03890
gene id: 1294273:ROSELON_RS03890
uniprot id: W8RZD6
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1294273:ROSELON RS15920
gene id: 1294273:ROSELON_RS15920
uniprot id: W8ST28
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

1294273:ROSELON RS12895
gene id: 1294273:ROSELON_RS12895
uniprot id: W8S7Z8
names: Function
names: Similarity
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.

1294273:ROSELON RS08855
gene id: 1294273:ROSELON_RS08855
uniprot id: W8S5X8
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS07445
gene id: 1294273:ROSELON_RS07445
uniprot id: W8RS35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1294273:ROSELON RS03275
gene id: 1294273:ROSELON_RS03275
uniprot id: W8RPM3
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).

1294273:ROSELON RS05120
gene id: 1294273:ROSELON_RS05120
uniprot id: W8SLT6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

1294273:ROSELON RS14020
gene id: 1294273:ROSELON_RS14020
uniprot id: W8S8I6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1294273:ROSELON RS00960
gene id: 1294273:ROSELON_RS00960
uniprot id: W8RNE4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1294273:ROSELON RS08190
gene id: 1294273:ROSELON_RS08190
uniprot id: W8SNJ8
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1294273:ROSELON RS11865
gene id: 1294273:ROSELON_RS11865
uniprot id: W8S7F3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1294273:ROSELON RS00790
gene id: 1294273:ROSELON_RS00790
uniprot id: W8RNB3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1294273:ROSELON RS01220
gene id: 1294273:ROSELON_RS01220
uniprot id: W8RNY3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1294273:ROSELON RS11245
gene id: 1294273:ROSELON_RS11245
uniprot id: W8SQB0
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1294273:ROSELON RS06595
gene id: 1294273:ROSELON_RS06595
uniprot id: W8S0U9
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.

1294273:ROSELON RS14850
gene id: 1294273:ROSELON_RS14850
uniprot id: W8RWA9
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS09695
gene id: 1294273:ROSELON_RS09695
uniprot id: W8S6F5
names: Similarity
messages: Belongs to the UPF0173 family.

1294273:ROSELON RS11535
gene id: 1294273:ROSELON_RS11535
uniprot id: W8RU95
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

1294273:ROSELON RS00175
gene id: 1294273:ROSELON_RS00175
uniprot id: W8RN23
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1294273:ROSELON RS12780
gene id: 1294273:ROSELON_RS12780
uniprot id: W8S4C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1294273:ROSELON RS04235
gene id: 1294273:ROSELON_RS04235
uniprot id: W8RZK2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1294273:ROSELON RS04230
gene id: 1294273:ROSELON_RS04230
uniprot id: W8S3G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1294273:ROSELON RS04380
gene id: 1294273:ROSELON_RS04380
uniprot id: W8RQ89
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

1294273:ROSELON RS07030
gene id: 1294273:ROSELON_RS07030
uniprot id: W8SMY2
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1294273:ROSELON RS03630
gene id: 1294273:ROSELON_RS03630
uniprot id: W8SKX8
names: Subunit
messages: Monomer.

1294273:ROSELON RS17005
gene id: 1294273:ROSELON_RS17005
uniprot id: W8S6I2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1294273:ROSELON RS04945
gene id: 1294273:ROSELON_RS04945
uniprot id: W8SLR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1294273:ROSELON RS08935
gene id: 1294273:ROSELON_RS08935
uniprot id: W8S237
names: Similarity
messages: Belongs to the UPF0235 family.

1294273:ROSELON RS15255
gene id: 1294273:ROSELON_RS15255
uniprot id: W8SSP1
names: Similarity
messages: Belongs to the DDAH family.

1294273:ROSELON RS07240
gene id: 1294273:ROSELON_RS07240
uniprot id: W8S556
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1294273:ROSELON RS04545
gene id: 1294273:ROSELON_RS04545
uniprot id: W8RQC9
names: Similarity
messages: Belongs to the PpiC/parvulin rotamase family.

1294273:ROSELON RS08295
gene id: 1294273:ROSELON_RS08295
uniprot id: W8S1T2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1294273:ROSELON RS00640
gene id: 1294273:ROSELON_RS00640
uniprot id: W8RN86
names: Similarity
messages: Belongs to the DSD1 family.

1294273:ROSELON RS04940
gene id: 1294273:ROSELON_RS04940
uniprot id: W8RQN5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1294273:ROSELON RS11540
gene id: 1294273:ROSELON_RS11540
uniprot id: W8SQH7
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1294273:ROSELON RS03840
gene id: 1294273:ROSELON_RS03840
uniprot id: W8RQ91
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1294273:ROSELON RS08255
gene id: 1294273:ROSELON_RS08255
uniprot id: W8RSG9
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1294273:ROSELON RS07435
gene id: 1294273:ROSELON_RS07435
uniprot id: W8S590
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1294273:ROSELON RS11620
gene id: 1294273:ROSELON_RS11620
uniprot id: W8S3N3
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1294273:ROSELON RS01485
gene id: 1294273:ROSELON_RS01485
uniprot id: W8RY47
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS04000
gene id: 1294273:ROSELON_RS04000
uniprot id: W8RQB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1294273:ROSELON RS10940
gene id: 1294273:ROSELON_RS10940
uniprot id: W8S6X4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1294273:ROSELON RS06315
gene id: 1294273:ROSELON_RS06315
uniprot id: W8S0Q0
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1294273:ROSELON RS13400
gene id: 1294273:ROSELON_RS13400
uniprot id: W8S889
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

1294273:ROSELON RS08590
gene id: 1294273:ROSELON_RS08590
uniprot id: W8SNT1
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1294273:ROSELON RS15770
gene id: 1294273:ROSELON_RS15770
uniprot id: W8RWE1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1294273:ROSELON RS16850
gene id: 1294273:ROSELON_RS16850
uniprot id: W8STK0
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1294273:ROSELON RS06535
gene id: 1294273:ROSELON_RS06535
uniprot id: W8S4N6
names: Similarity
messages: Belongs to the SCO1/2 family.

1294273:ROSELON RS13240
gene id: 1294273:ROSELON_RS13240
uniprot id: W8SRH6
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1294273:ROSELON RS03165
gene id: 1294273:ROSELON_RS03165
uniprot id: W8SKQ2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1294273:ROSELON RS14095
gene id: 1294273:ROSELON_RS14095
uniprot id: W8S8K3
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1294273:ROSELON RS15285
gene id: 1294273:ROSELON_RS15285
uniprot id: W8RW59
names: Similarity
messages: Belongs to the thioredoxin family. DsbE subfamily.

1294273:ROSELON RS00485
gene id: 1294273:ROSELON_RS00485
uniprot id: W8SJ91
names: Similarity
messages: Belongs to the aspartokinase family.

1294273:ROSELON RS07710
gene id: 1294273:ROSELON_RS07710
uniprot id: W8RSE3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1294273:ROSELON RS07970
gene id: 1294273:ROSELON_RS07970
uniprot id: W8RSC2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1294273:ROSELON RS14295
gene id: 1294273:ROSELON_RS14295
uniprot id: W8SS36
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1294273:ROSELON RS01165
gene id: 1294273:ROSELON_RS01165
uniprot id: W8S1U3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

1294273:ROSELON RS09815
gene id: 1294273:ROSELON_RS09815
uniprot id: W8SPL2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1294273:ROSELON RS06815
gene id: 1294273:ROSELON_RS06815
uniprot id: W8RRU7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1294273:ROSELON RS08205
gene id: 1294273:ROSELON_RS08205
uniprot id: W8RSL3
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

1294273:ROSELON RS16240
gene id: 1294273:ROSELON_RS16240
uniprot id: W8S9Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Probably responsible for the translocation of the substrate across the membrane.
messages: Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).

1294273:ROSELON RS16970
gene id: 1294273:ROSELON_RS16970
uniprot id: W8STM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.
messages: The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.

1294273:ROSELON RS00930
gene id: 1294273:ROSELON_RS00930
uniprot id: W8RNS4
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1294273:ROSELON RS01200
gene id: 1294273:ROSELON_RS01200
uniprot id: W8RNX8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

1294273:ROSELON RS12790
gene id: 1294273:ROSELON_RS12790
uniprot id: W8RV14
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1294273:ROSELON RS01530
gene id: 1294273:ROSELON_RS01530
uniprot id: W8SJT9
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

1294273:ROSELON RS05135
gene id: 1294273:ROSELON_RS05135
uniprot id: W8RR02
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS12035
gene id: 1294273:ROSELON_RS12035
uniprot id: W8RUK7
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1294273:ROSELON RS04440
gene id: 1294273:ROSELON_RS04440
uniprot id: W8RZQ0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1294273:ROSELON RS06190
gene id: 1294273:ROSELON_RS06190
uniprot id: W8RRJ6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of five rings (E,L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1294273:ROSELON RS12180
gene id: 1294273:ROSELON_RS12180
uniprot id: W8RUR2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1294273:ROSELON RS02660
gene id: 1294273:ROSELON_RS02660
uniprot id: W8RPD8
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS14990
gene id: 1294273:ROSELON_RS14990
uniprot id: W8RW22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

1294273:ROSELON RS08680
gene id: 1294273:ROSELON_RS08680
uniprot id: W8S1Z5
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this 1-Cys peroxiredoxin, no C(R) is present and C(P) instead forms a disulfide with a cysteine from another protein or with a small thiol molecule.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1294273:ROSELON RS07395
gene id: 1294273:ROSELON_RS07395
uniprot id: W8RS86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1294273:ROSELON RS00995
gene id: 1294273:ROSELON_RS00995
uniprot id: W8S1R1
names: Function
names: Similarity
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.

1294273:ROSELON RS03425
gene id: 1294273:ROSELON_RS03425
uniprot id: W8RPP7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1294273:ROSELON RS15160
gene id: 1294273:ROSELON_RS15160
uniprot id: W8RW42
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS10500
gene id: 1294273:ROSELON_RS10500
uniprot id: W8RTN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

1294273:ROSELON RS00065
gene id: 1294273:ROSELON_RS00065
uniprot id: W8SJ21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1294273:ROSELON RS08125
gene id: 1294273:ROSELON_RS08125
uniprot id: W8S1Q3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

1294273:ROSELON RS07475
gene id: 1294273:ROSELON_RS07475
uniprot id: W8S598
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1294273:ROSELON RS06145
gene id: 1294273:ROSELON_RS06145
uniprot id: W8RR89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1294273:ROSELON RS16115
gene id: 1294273:ROSELON_RS16115
uniprot id: W8RWK0
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1294273:ROSELON RS01170
gene id: 1294273:ROSELON_RS01170
uniprot id: W8RXZ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1294273:ROSELON RS12610
gene id: 1294273:ROSELON_RS12610
uniprot id: W8S7V5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1294273:ROSELON RS14615
gene id: 1294273:ROSELON_RS14615
uniprot id: W8RW63
names: Similarity
messages: Belongs to the PpiC/parvulin rotamase family.

1294273:ROSELON RS12710
gene id: 1294273:ROSELON_RS12710
uniprot id: W8S4B1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COX15/CtaA family. Type 2 subfamily.
messages: Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8. The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
messages: Cell membrane
messages: Interacts with CtaB.
messages: Membrane

1294273:ROSELON RS16815
gene id: 1294273:ROSELON_RS16815
uniprot id: W8S6E7
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1294273:ROSELON RS11675
gene id: 1294273:ROSELON_RS11675
uniprot id: W8RUB3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1294273:ROSELON RS12670
gene id: 1294273:ROSELON_RS12670
uniprot id: W8RUV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1294273:ROSELON RS03185
gene id: 1294273:ROSELON_RS03185
uniprot id: W8RPK9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1294273:ROSELON RS03510
gene id: 1294273:ROSELON_RS03510
uniprot id: W8RZ67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

1294273:ROSELON RS02405
gene id: 1294273:ROSELON_RS02405
uniprot id: W8RPA0
names: Similarity
messages: Belongs to the MreC family.

1294273:ROSELON RS07375
gene id: 1294273:ROSELON_RS07375
uniprot id: W8RS24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1294273:ROSELON RS13765
gene id: 1294273:ROSELON_RS13765
uniprot id: W8SRS5
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1294273:ROSELON RS15035
gene id: 1294273:ROSELON_RS15035
uniprot id: W8RW28
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1294273:ROSELON RS16230
gene id: 1294273:ROSELON_RS16230
uniprot id: W8RX00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1294273:ROSELON RS09275
gene id: 1294273:ROSELON_RS09275
uniprot id: W8SP74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1294273:ROSELON RS13390
gene id: 1294273:ROSELON_RS13390
uniprot id: W8RV72
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1294273:ROSELON RS17050
gene id: 1294273:ROSELON_RS17050
uniprot id: W8STP6
names: Similarity
messages: Belongs to the RecJ family.

1294273:ROSELON RS06300
gene id: 1294273:ROSELON_RS06300
uniprot id: W8RRB9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1294273:ROSELON RS16965
gene id: 1294273:ROSELON_RS16965
uniprot id: W8RXE4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

1294273:ROSELON RS03970
gene id: 1294273:ROSELON_RS03970
uniprot id: W8RZF2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

1294273:ROSELON RS09075
gene id: 1294273:ROSELON_RS09075
uniprot id: W8S614
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1294273:ROSELON RS07385
gene id: 1294273:ROSELON_RS07385
uniprot id: W8S583
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1294273:ROSELON RS06475
gene id: 1294273:ROSELON_RS06475
uniprot id: W8RRN9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1294273:ROSELON RS05885
gene id: 1294273:ROSELON_RS05885
uniprot id: W8SM73
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1294273:ROSELON RS01815
gene id: 1294273:ROSELON_RS01815
uniprot id: W8RNW3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1294273:ROSELON RS12360
gene id: 1294273:ROSELON_RS12360
uniprot id: W8S7R6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1294273:ROSELON RS13945
gene id: 1294273:ROSELON_RS13945
uniprot id: W8S4X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

1294273:ROSELON RS03385
gene id: 1294273:ROSELON_RS03385
uniprot id: W8SKT6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1294273:ROSELON RS07585
gene id: 1294273:ROSELON_RS07585
uniprot id: W8RSC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1294273:ROSELON RS07875
gene id: 1294273:ROSELON_RS07875
uniprot id: W8S5E9
names: Function
names: Similarity
messages: A possible function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex.
messages: Belongs to the bacterial AtpI family.

1294273:ROSELON RS03315
gene id: 1294273:ROSELON_RS03315
uniprot id: W8RZ35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1294273:ROSELON RS13755
gene id: 1294273:ROSELON_RS13755
uniprot id: W8RVC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1294273:ROSELON RS03800
gene id: 1294273:ROSELON_RS03800
uniprot id: W8SL09
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1294273:ROSELON RS12395
gene id: 1294273:ROSELON_RS12395
uniprot id: W8RUQ8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1294273:ROSELON RS07090
gene id: 1294273:ROSELON_RS07090
uniprot id: W8S158
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1294273:ROSELON RS00350
gene id: 1294273:ROSELON_RS00350
uniprot id: W8SJ70
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1294273:ROSELON RS01230
gene id: 1294273:ROSELON_RS01230
uniprot id: W8SJM9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1294273:ROSELON RS10635
gene id: 1294273:ROSELON_RS10635
uniprot id: W8RTR0
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

1294273:ROSELON RS05895
gene id: 1294273:ROSELON_RS05895
uniprot id: W8S0H8
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1294273:ROSELON RS07895
gene id: 1294273:ROSELON_RS07895
uniprot id: W8SNF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1294273:ROSELON RS07415
gene id: 1294273:ROSELON_RS07415
uniprot id: W8S1D9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1294273:ROSELON RS01900
gene id: 1294273:ROSELON_RS01900
uniprot id: W8RYD8
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1294273:ROSELON RS15855
gene id: 1294273:ROSELON_RS15855
uniprot id: W8ST13
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1294273:ROSELON RS00050
gene id: 1294273:ROSELON_RS00050
uniprot id: W8RXF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1294273:ROSELON RS03090
gene id: 1294273:ROSELON_RS03090
uniprot id: W8RPJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1294273:ROSELON RS10735
gene id: 1294273:ROSELON_RS10735
uniprot id: W8RTU8
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1294273:ROSELON RS08785
gene id: 1294273:ROSELON_RS08785
uniprot id: W8RSQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

1294273:ROSELON RS07260
gene id: 1294273:ROSELON_RS07260
uniprot id: W8SN56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1294273:ROSELON RS02350
gene id: 1294273:ROSELON_RS02350
uniprot id: W8RYN3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1294273:ROSELON RS03235
gene id: 1294273:ROSELON_RS03235
uniprot id: W8S2Z1
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1294273:ROSELON RS11785
gene id: 1294273:ROSELON_RS11785
uniprot id: W8S7D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1294273:ROSELON RS02610
gene id: 1294273:ROSELON_RS02610
uniprot id: W8RPD2
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1294273:ROSELON RS01300
gene id: 1294273:ROSELON_RS01300
uniprot id: W8RY14
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1294273:ROSELON RS02585
gene id: 1294273:ROSELON_RS02585
uniprot id: W8RPC7
names: Subcellular Location Annotation
messages: Periplasm

1294273:ROSELON RS02895
gene id: 1294273:ROSELON_RS02895
uniprot id: W8RPH0
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1294273:ROSELON RS06290
gene id: 1294273:ROSELON_RS06290
uniprot id: W8S0P5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1294273:ROSELON RS17085
gene id: 1294273:ROSELON_RS17085
uniprot id: W8SA78
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1294273:ROSELON RS07310
gene id: 1294273:ROSELON_RS07310
uniprot id: W8S549
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1294273:ROSELON RS00130
gene id: 1294273:ROSELON_RS00130
uniprot id: W8RNC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1294273:ROSELON RS09335
gene id: 1294273:ROSELON_RS09335
uniprot id: W8SP89
names: Subcellular Location Annotation
messages: Mitochondrion

1294273:ROSELON RS17040
gene id: 1294273:ROSELON_RS17040
uniprot id: W8RXG2
names: Similarity
messages: Belongs to the FBPase class 2 family.

1294273:ROSELON RS11325
gene id: 1294273:ROSELON_RS11325
uniprot id: W8S731
names: Similarity
messages: Belongs to the peptidase C40 family.

1294273:ROSELON RS03910
gene id: 1294273:ROSELON_RS03910
uniprot id: W8S3A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1294273:ROSELON RS10480
gene id: 1294273:ROSELON_RS10480
uniprot id: W8SPW7
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1294273:ROSELON RS10330
gene id: 1294273:ROSELON_RS10330
uniprot id: W8RTK0
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1294273:ROSELON RS05130
gene id: 1294273:ROSELON_RS05130
uniprot id: W8S044
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PucC family.
messages: Membrane

1294273:ROSELON RS00435
gene id: 1294273:ROSELON_RS00435
uniprot id: W8S1F4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1294273:ROSELON RS15720
gene id: 1294273:ROSELON_RS15720
uniprot id: W8RWD4
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1294273:ROSELON RS04470
gene id: 1294273:ROSELON_RS04470
uniprot id: W8RQB2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1294273:ROSELON RS06120
gene id: 1294273:ROSELON_RS06120
uniprot id: W8RR83
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1294273:ROSELON RS07425
gene id: 1294273:ROSELON_RS07425
uniprot id: W8RS32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1294273:ROSELON RS02460
gene id: 1294273:ROSELON_RS02460
uniprot id: W8SKE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1294273:ROSELON RS02090
gene id: 1294273:ROSELON_RS02090
uniprot id: W8SK59
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1294273:ROSELON RS03010
gene id: 1294273:ROSELON_RS03010
uniprot id: W8RPW0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

1294273:ROSELON RS14930
gene id: 1294273:ROSELON_RS14930
uniprot id: W8SSJ2
names: Similarity
messages: Belongs to the PpiC/parvulin rotamase family.

1294273:ROSELON RS13475
gene id: 1294273:ROSELON_RS13475
uniprot id: W8SRM0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1294273:ROSELON RS04845
gene id: 1294273:ROSELON_RS04845
uniprot id: W8SLP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1294273:ROSELON RS16785
gene id: 1294273:ROSELON_RS16785
uniprot id: W8STI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1294273:ROSELON RS11520
gene id: 1294273:ROSELON_RS11520
uniprot id: W8S3L2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1294273:ROSELON RS11125
gene id: 1294273:ROSELON_RS11125
uniprot id: W8S3B8
names: Similarity
messages: Belongs to the leucine-binding protein family.

1294273:ROSELON RS07265
gene id: 1294273:ROSELON_RS07265
uniprot id: W8S561
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1294273:ROSELON RS16910
gene id: 1294273:ROSELON_RS16910
uniprot id: W8S6G5
names: Similarity
messages: Belongs to the GST superfamily.

1294273:ROSELON RS12345
gene id: 1294273:ROSELON_RS12345
uniprot id: W8S454
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1294273:ROSELON RS05110
gene id: 1294273:ROSELON_RS05110
uniprot id: W8RQZ9
names: Function
names: PTM
messages: Binds 4 heme groups per subunit.
messages: The reaction center of purple bacteria contains a tightly bound cytochrome molecule which re-reduces the photo oxidized primary electron donor.

1294273:ROSELON RS06170
gene id: 1294273:ROSELON_RS06170
uniprot id: W8RR94
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

1294273:ROSELON RS15805
gene id: 1294273:ROSELON_RS15805
uniprot id: W8ST02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1294273:ROSELON RS03730
gene id: 1294273:ROSELON_RS03730
uniprot id: W8S372
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1294273:ROSELON RS13990
gene id: 1294273:ROSELON_RS13990
uniprot id: W8SRX4
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1294273:ROSELON RS10370
gene id: 1294273:ROSELON_RS10370
uniprot id: W8S2Y5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1294273:ROSELON RS09070
gene id: 1294273:ROSELON_RS09070
uniprot id: W8SP32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

1294273:ROSELON RS15800
gene id: 1294273:ROSELON_RS15800
uniprot id: W8RWR2
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1294273:ROSELON RS06750
gene id: 1294273:ROSELON_RS06750
uniprot id: W8RRL5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1294273:ROSELON RS09080
gene id: 1294273:ROSELON_RS09080
uniprot id: W8S266
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1294273:ROSELON RS08055
gene id: 1294273:ROSELON_RS08055
uniprot id: W8S1P0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and a hydrophobic anchor protein.

1294273:ROSELON RS08720
gene id: 1294273:ROSELON_RS08720
uniprot id: W8S5V6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1294273:ROSELON RS16655
gene id: 1294273:ROSELON_RS16655
uniprot id: W8S9W4
names: Function
names: Similarity
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.

1294273:ROSELON RS16095
gene id: 1294273:ROSELON_RS16095
uniprot id: W8RWX3
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1294273:ROSELON RS16105
gene id: 1294273:ROSELON_RS16105
uniprot id: W8S9N2
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

1294273:ROSELON RS14545
gene id: 1294273:ROSELON_RS14545
uniprot id: W8SS93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

1294273:ROSELON RS04280
gene id: 1294273:ROSELON_RS04280
uniprot id: W8SL97
names: Function
messages: Acts on leucine, isoleucine and valine.

1294273:ROSELON RS06575
gene id: 1294273:ROSELON_RS06575
uniprot id: W8RRQ5
names: Similarity
messages: Belongs to the thioredoxin family.

1294273:ROSELON RS08110
gene id: 1294273:ROSELON_RS08110
uniprot id: W8RSE6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1294273:ROSELON RS01440
gene id: 1294273:ROSELON_RS01440
uniprot id: W8RY38
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1294273:ROSELON RS06080
gene id: 1294273:ROSELON_RS06080
uniprot id: W8SMB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1294273:ROSELON RS05445
gene id: 1294273:ROSELON_RS05445
uniprot id: W8RQW4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1294273:ROSELON RS07300
gene id: 1294273:ROSELON_RS07300
uniprot id: W8RS17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1294273:ROSELON RS04665
gene id: 1294273:ROSELON_RS04665
uniprot id: W8RQG0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1294273:ROSELON RS15540
gene id: 1294273:ROSELON_RS15540
uniprot id: W8RWM0
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

1294273:ROSELON RS10290
gene id: 1294273:ROSELON_RS10290
uniprot id: W8S6M8
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1294273:ROSELON RS04500
gene id: 1294273:ROSELON_RS04500
uniprot id: W8SLE0
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

1294273:ROSELON RS03025
gene id: 1294273:ROSELON_RS03025
uniprot id: W8S2V8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

1294273:ROSELON RS07420
gene id: 1294273:ROSELON_RS07420
uniprot id: W8RS91
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1294273:ROSELON RS02655
gene id: 1294273:ROSELON_RS02655
uniprot id: W8RPQ7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1294273:ROSELON RS12605
gene id: 1294273:ROSELON_RS12605
uniprot id: W8SR61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1294273:ROSELON RS06225
gene id: 1294273:ROSELON_RS06225
uniprot id: W8RRA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Membrane

1294273:ROSELON RS10135
gene id: 1294273:ROSELON_RS10135
uniprot id: W8SPR5
names: Similarity
messages: Belongs to the CobH/CbiC family.

1294273:ROSELON RS15700
gene id: 1294273:ROSELON_RS15700
uniprot id: W8RWD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1294273:ROSELON RS05000
gene id: 1294273:ROSELON_RS05000
uniprot id: W8S3W8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1294273:ROSELON RS00075
gene id: 1294273:ROSELON_RS00075
uniprot id: W8RXF8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1294273:ROSELON RS03555
gene id: 1294273:ROSELON_RS03555
uniprot id: W8SKW5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1294273:ROSELON RS04800
gene id: 1294273:ROSELON_RS04800
uniprot id: W8RZZ7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1294273:ROSELON RS05050
gene id: 1294273:ROSELON_RS05050
uniprot id: W8S3X6
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1294273:ROSELON RS16390
gene id: 1294273:ROSELON_RS16390
uniprot id: W8RWP2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1294273:ROSELON RS00710
gene id: 1294273:ROSELON_RS00710
uniprot id: W8SJC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1294273:ROSELON RS07200
gene id: 1294273:ROSELON_RS07200
uniprot id: W8RS52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1294273:ROSELON RS00100
gene id: 1294273:ROSELON_RS00100
uniprot id: W8RXG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1294273:ROSELON RS13320
gene id: 1294273:ROSELON_RS13320
uniprot id: W8S876
names: Similarity
messages: Belongs to the GcvT family.

1294273:ROSELON RS00965
gene id: 1294273:ROSELON_RS00965
uniprot id: W8SJI4
names: Similarity
messages: Belongs to the PhzF family.

1294273:ROSELON RS04510
gene id: 1294273:ROSELON_RS04510
uniprot id: W8RZR9
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

1294273:ROSELON RS14560
gene id: 1294273:ROSELON_RS14560
uniprot id: W8RVU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

1294273:ROSELON RS10165
gene id: 1294273:ROSELON_RS10165
uniprot id: W8S6K9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1294273:ROSELON RS13020
gene id: 1294273:ROSELON_RS13020
uniprot id: W8RV07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

1294273:ROSELON RS00900
gene id: 1294273:ROSELON_RS00900
uniprot id: W8RXU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1294273:ROSELON RS06165
gene id: 1294273:ROSELON_RS06165
uniprot id: W8RRJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cytoplasm

1294273:ROSELON RS07075
gene id: 1294273:ROSELON_RS07075
uniprot id: W8RRT8
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1294273:ROSELON RS03810
gene id: 1294273:ROSELON_RS03810
uniprot id: W8RZC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1294273:ROSELON RS13435
gene id: 1294273:ROSELON_RS13435
uniprot id: W8S4N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1294273:ROSELON RS09495
gene id: 1294273:ROSELON_RS09495
uniprot id: W8S692
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1294273:ROSELON RS14375
gene id: 1294273:ROSELON_RS14375
uniprot id: W8S8R1
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS11425
gene id: 1294273:ROSELON_RS11425
uniprot id: W8SQE8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1294273:ROSELON RS07025
gene id: 1294273:ROSELON_RS07025
uniprot id: W8RRS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1294273:ROSELON RS11695
gene id: 1294273:ROSELON_RS11695
uniprot id: W8S3P5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1294273:ROSELON RS07010
gene id: 1294273:ROSELON_RS07010
uniprot id: W8S4Y5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1294273:ROSELON RS01690
gene id: 1294273:ROSELON_RS01690
uniprot id: W8SJX1
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS04960
gene id: 1294273:ROSELON_RS04960
uniprot id: W8RQX3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1294273:ROSELON RS03815
gene id: 1294273:ROSELON_RS03815
uniprot id: W8RQ86
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1294273:ROSELON RS16520
gene id: 1294273:ROSELON_RS16520
uniprot id: W8STC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1294273:ROSELON RS00660
gene id: 1294273:ROSELON_RS00660
uniprot id: W8RNL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

1294273:ROSELON RS07160
gene id: 1294273:ROSELON_RS07160
uniprot id: W8SN39
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS03040
gene id: 1294273:ROSELON_RS03040
uniprot id: W8RPI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1294273:ROSELON RS15480
gene id: 1294273:ROSELON_RS15480
uniprot id: W8S9C3
names: Similarity
messages: Belongs to the peptidase C56 family.

1294273:ROSELON RS14895
gene id: 1294273:ROSELON_RS14895
uniprot id: W8RW09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1294273:ROSELON RS11595
gene id: 1294273:ROSELON_RS11595
uniprot id: W8S3M7
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

1294273:ROSELON RS09755
gene id: 1294273:ROSELON_RS09755
uniprot id: W8RTB0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1294273:ROSELON RS05030
gene id: 1294273:ROSELON_RS05030
uniprot id: W8S028
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1294273:ROSELON RS13740
gene id: 1294273:ROSELON_RS13740
uniprot id: W8SRR9
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS02645
gene id: 1294273:ROSELON_RS02645
uniprot id: W8S2P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1294273:ROSELON RS07355
gene id: 1294273:ROSELON_RS07355
uniprot id: W8SN70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1294273:ROSELON RS10235
gene id: 1294273:ROSELON_RS10235
uniprot id: W8S6M1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1294273:ROSELON RS17620
gene id: 1294273:ROSELON_RS17620
uniprot id: W8RWQ2
names: Subcellular Location Annotation
messages: Secreted

1294273:ROSELON RS13935
gene id: 1294273:ROSELON_RS13935
uniprot id: W8SRW3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1294273:ROSELON RS04985
gene id: 1294273:ROSELON_RS04985
uniprot id: W8RQX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

1294273:ROSELON RS06550
gene id: 1294273:ROSELON_RS06550
uniprot id: W8RRQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1294273:ROSELON RS06105
gene id: 1294273:ROSELON_RS06105
uniprot id: W8S4G6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1294273:ROSELON RS14160
gene id: 1294273:ROSELON_RS14160
uniprot id: W8RVT0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1294273:ROSELON RS06765
gene id: 1294273:ROSELON_RS06765
uniprot id: W8S0Y6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1294273:ROSELON RS15455
gene id: 1294273:ROSELON_RS15455
uniprot id: W8S9B9
names: Similarity
messages: Belongs to the peptidase M1 family.

1294273:ROSELON RS12550
gene id: 1294273:ROSELON_RS12550
uniprot id: W8SR50
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1294273:ROSELON RS00095
gene id: 1294273:ROSELON_RS00095
uniprot id: W8S198
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1294273:ROSELON RS00155
gene id: 1294273:ROSELON_RS00155
uniprot id: W8RN19
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

1294273:ROSELON RS07885
gene id: 1294273:ROSELON_RS07885
uniprot id: W8RSG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1294273:ROSELON RS00890
gene id: 1294273:ROSELON_RS00890
uniprot id: W8SJG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1294273:ROSELON RS01860
gene id: 1294273:ROSELON_RS01860
uniprot id: W8RNX5
names: Similarity
messages: Belongs to the UPF0102 family.

1294273:ROSELON RS07085
gene id: 1294273:ROSELON_RS07085
uniprot id: W8S502
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1294273:ROSELON RS11055
gene id: 1294273:ROSELON_RS11055
uniprot id: W8RTZ3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1294273:ROSELON RS14520
gene id: 1294273:ROSELON_RS14520
uniprot id: W8SS87
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1294273:ROSELON RS10180
gene id: 1294273:ROSELON_RS10180
uniprot id: W8RTH1
names: Function
messages: Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A.

1294273:ROSELON RS10425
gene id: 1294273:ROSELON_RS10425
uniprot id: W8RTL9
names: Function
names: Similarity
messages: Belongs to the ribose 1,5-bisphosphokinase family.
messages: Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).

1294273:ROSELON RS01495
gene id: 1294273:ROSELON_RS01495
uniprot id: W8SJT5
names: Subcellular Location Annotation
messages: Cell inner membrane

1294273:ROSELON RS00440
gene id: 1294273:ROSELON_RS00440
uniprot id: W8RXL6
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1294273:ROSELON RS04155
gene id: 1294273:ROSELON_RS04155
uniprot id: W8RZI6
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1294273:ROSELON RS06820
gene id: 1294273:ROSELON_RS06820
uniprot id: W8RRN0
names: Caution
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1294273:ROSELON RS14300
gene id: 1294273:ROSELON_RS14300
uniprot id: W8S8P4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

1294273:ROSELON RS01235
gene id: 1294273:ROSELON_RS01235
uniprot id: W8S1V8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1294273:ROSELON RS01785
gene id: 1294273:ROSELON_RS01785
uniprot id: W8RP84
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1294273:ROSELON RS00910
gene id: 1294273:ROSELON_RS00910
uniprot id: W8RND3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1294273:ROSELON RS12285
gene id: 1294273:ROSELON_RS12285
uniprot id: W8RUS9
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

1294273:ROSELON RS12090
gene id: 1294273:ROSELON_RS12090
uniprot id: W8S7M7
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

1294273:ROSELON RS04480
gene id: 1294273:ROSELON_RS04480
uniprot id: W8S3M1
names: Similarity
messages: Belongs to the peptidase S41A family.

1294273:ROSELON RS03955
gene id: 1294273:ROSELON_RS03955
uniprot id: W8SL35
names: Similarity
messages: Belongs to the thioredoxin family.

1294273:ROSELON RS10605
gene id: 1294273:ROSELON_RS10605
uniprot id: W8RTS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1294273:ROSELON RS04950
gene id: 1294273:ROSELON_RS04950
uniprot id: W8S3W3
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

1294273:ROSELON RS13285
gene id: 1294273:ROSELON_RS13285
uniprot id: W8RVB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1294273:ROSELON RS16220
gene id: 1294273:ROSELON_RS16220
uniprot id: W8RWL8
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1294273:ROSELON RS07040
gene id: 1294273:ROSELON_RS07040
uniprot id: W8S144
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1294273:ROSELON RS16580
gene id: 1294273:ROSELON_RS16580
uniprot id: W8STE0
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS04100
gene id: 1294273:ROSELON_RS04100
uniprot id: W8RQD9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1294273:ROSELON RS09705
gene id: 1294273:ROSELON_RS09705
uniprot id: W8RTD6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1294273:ROSELON RS09370
gene id: 1294273:ROSELON_RS09370
uniprot id: W8S2C5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1294273:ROSELON RS12475
gene id: 1294273:ROSELON_RS12475
uniprot id: W8RUS0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1294273:ROSELON RS10620
gene id: 1294273:ROSELON_RS10620
uniprot id: W8S6S5
names: Similarity
messages: Belongs to the DapA family.

1294273:ROSELON RS10775
gene id: 1294273:ROSELON_RS10775
uniprot id: W8S6U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1294273:ROSELON RS04680
gene id: 1294273:ROSELON_RS04680
uniprot id: W8RZW0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

1294273:ROSELON RS08650
gene id: 1294273:ROSELON_RS08650
uniprot id: W8S5U2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

1294273:ROSELON RS14325
gene id: 1294273:ROSELON_RS14325
uniprot id: W8S8Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1294273:ROSELON RS14515
gene id: 1294273:ROSELON_RS14515
uniprot id: W8RW17
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

1294273:ROSELON RS11915
gene id: 1294273:ROSELON_RS11915
uniprot id: W8S7G4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1294273:ROSELON RS10545
gene id: 1294273:ROSELON_RS10545
uniprot id: W8RTR7
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1294273:ROSELON RS09600
gene id: 1294273:ROSELON_RS09600
uniprot id: W8S2G5
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1294273:ROSELON RS02340
gene id: 1294273:ROSELON_RS02340
uniprot id: W8SKC2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1294273:ROSELON RS02955
gene id: 1294273:ROSELON_RS02955
uniprot id: W8RPV1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1294273:ROSELON RS00850
gene id: 1294273:ROSELON_RS00850
uniprot id: W8RNR2
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1294273:ROSELON RS07020
gene id: 1294273:ROSELON_RS07020
uniprot id: W8RRY6
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1294273:ROSELON RS06520
gene id: 1294273:ROSELON_RS06520
uniprot id: W8RRG8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1294273:ROSELON RS04320
gene id: 1294273:ROSELON_RS04320
uniprot id: W8RQH4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

1294273:ROSELON RS05370
gene id: 1294273:ROSELON_RS05370
uniprot id: W8S087
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1294273:ROSELON RS04770
gene id: 1294273:ROSELON_RS04770
uniprot id: W8S3U1
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1294273:ROSELON RS02720
gene id: 1294273:ROSELON_RS02720
uniprot id: W8RYU2
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

1294273:ROSELON RS07325
gene id: 1294273:ROSELON_RS07325
uniprot id: W8RS19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1294273:ROSELON RS12350
gene id: 1294273:ROSELON_RS12350
uniprot id: W8RUQ0
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1294273:ROSELON RS10350
gene id: 1294273:ROSELON_RS10350
uniprot id: W8RTN7
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1294273:ROSELON RS13215
gene id: 1294273:ROSELON_RS13215
uniprot id: W8RVA1
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS14565
gene id: 1294273:ROSELON_RS14565
uniprot id: W8SSC2
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1294273:ROSELON RS13785
gene id: 1294273:ROSELON_RS13785
uniprot id: W8RVK4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1294273:ROSELON RS01730
gene id: 1294273:ROSELON_RS01730
uniprot id: W8RYA0
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS00535
gene id: 1294273:ROSELON_RS00535
uniprot id: W8S1H1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1294273:ROSELON RS16585
gene id: 1294273:ROSELON_RS16585
uniprot id: W8S9V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1294273:ROSELON RS01415
gene id: 1294273:ROSELON_RS01415
uniprot id: W8RY33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1294273:ROSELON RS12850
gene id: 1294273:ROSELON_RS12850
uniprot id: W8S4D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1294273:ROSELON RS01365
gene id: 1294273:ROSELON_RS01365
uniprot id: W8RP14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Cell inner membrane
messages: Membrane
messages: Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.

1294273:ROSELON RS06245
gene id: 1294273:ROSELON_RS06245
uniprot id: W8RRK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1294273:ROSELON RS01965
gene id: 1294273:ROSELON_RS01965
uniprot id: W8SK37
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1294273:ROSELON RS11660
gene id: 1294273:ROSELON_RS11660
uniprot id: W8SQK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Could be part of an ABC transporter complex.
messages: Membrane

1294273:ROSELON RS02665
gene id: 1294273:ROSELON_RS02665
uniprot id: W8SKH4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1294273:ROSELON RS09955
gene id: 1294273:ROSELON_RS09955
uniprot id: W8SPN4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1294273:ROSELON RS07550
gene id: 1294273:ROSELON_RS07550
uniprot id: W8S1F9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1294273:ROSELON RS14645
gene id: 1294273:ROSELON_RS14645
uniprot id: W8SSE7
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1294273:ROSELON RS01930
gene id: 1294273:ROSELON_RS01930
uniprot id: W8RPB9
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1294273:ROSELON RS09025
gene id: 1294273:ROSELON_RS09025
uniprot id: W8SP21
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1294273:ROSELON RS16550
gene id: 1294273:ROSELON_RS16550
uniprot id: W8STD5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1294273:ROSELON RS02135
gene id: 1294273:ROSELON_RS02135
uniprot id: W8RP58
names: Similarity
messages: Belongs to the TrpF family.

1294273:ROSELON RS03490
gene id: 1294273:ROSELON_RS03490
uniprot id: W8S328
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

1294273:ROSELON RS09650
gene id: 1294273:ROSELON_RS09650
uniprot id: W8S6E8
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1294273:ROSELON RS05650
gene id: 1294273:ROSELON_RS05650
uniprot id: W8S482
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1294273:ROSELON RS11740
gene id: 1294273:ROSELON_RS11740
uniprot id: W8S7C7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1294273:ROSELON RS03030
gene id: 1294273:ROSELON_RS03030
uniprot id: W8RYY9
names: Subcellular Location Annotation
messages: Cell inner membrane

1294273:ROSELON RS06590
gene id: 1294273:ROSELON_RS06590
uniprot id: W8S4P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1294273:ROSELON RS16900
gene id: 1294273:ROSELON_RS16900
uniprot id: W8STK8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1294273:ROSELON RS05700
gene id: 1294273:ROSELON_RS05700
uniprot id: W8S491
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1294273:ROSELON RS08385
gene id: 1294273:ROSELON_RS08385
uniprot id: W8RSI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1294273:ROSELON RS15960
gene id: 1294273:ROSELON_RS15960
uniprot id: W8RWH2
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1294273:ROSELON RS12570
gene id: 1294273:ROSELON_RS12570
uniprot id: W8S7U9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1294273:ROSELON RS07755
gene id: 1294273:ROSELON_RS07755
uniprot id: W8S1J0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1294273:ROSELON RS11850
gene id: 1294273:ROSELON_RS11850
uniprot id: W8RUE8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1294273:ROSELON RS06660
gene id: 1294273:ROSELON_RS06660
uniprot id: W8S0W3
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1294273:ROSELON RS09835
gene id: 1294273:ROSELON_RS09835
uniprot id: W8RTF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1294273:ROSELON RS14530
gene id: 1294273:ROSELON_RS14530
uniprot id: W8S592
names: Similarity
messages: Belongs to the HIBADH-related family.

1294273:ROSELON RS13620
gene id: 1294273:ROSELON_RS13620
uniprot id: W8S8C1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1294273:ROSELON RS11390
gene id: 1294273:ROSELON_RS11390
uniprot id: W8RU59
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1294273:ROSELON RS10240
gene id: 1294273:ROSELON_RS10240
uniprot id: W8S2W6
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

1294273:ROSELON RS12260
gene id: 1294273:ROSELON_RS12260
uniprot id: W8RUS3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1294273:ROSELON RS12155
gene id: 1294273:ROSELON_RS12155
uniprot id: W8RUM5
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS04285
gene id: 1294273:ROSELON_RS04285
uniprot id: W8S3H3
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1294273:ROSELON RS01000
gene id: 1294273:ROSELON_RS01000
uniprot id: W8RXW5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1294273:ROSELON RS11340
gene id: 1294273:ROSELON_RS11340
uniprot id: W8RU49
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1294273:ROSELON RS01765
gene id: 1294273:ROSELON_RS01765
uniprot id: W8RNV2
names: Similarity
messages: Belongs to the NTE family.

1294273:ROSELON RS03540
gene id: 1294273:ROSELON_RS03540
uniprot id: W8RQ41
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1294273:ROSELON RS07465
gene id: 1294273:ROSELON_RS07465
uniprot id: W8RS38
names: Similarity
messages: Belongs to the autoinducer synthase family.

1294273:ROSELON RS08200
gene id: 1294273:ROSELON_RS08200
uniprot id: W8S1R5
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1294273:ROSELON RS14350
gene id: 1294273:ROSELON_RS14350
uniprot id: W8SS46
names: Similarity
messages: Belongs to the bacterial glucokinase family.

1294273:ROSELON RS01585
gene id: 1294273:ROSELON_RS01585
uniprot id: W8RP42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PucC family.
messages: Membrane

1294273:ROSELON RS13455
gene id: 1294273:ROSELON_RS13455
uniprot id: W8S899
names: Caution
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Belongs to the IspF family.
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1294273:ROSELON RS06790
gene id: 1294273:ROSELON_RS06790
uniprot id: W8S0Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1294273:ROSELON RS03070
gene id: 1294273:ROSELON_RS03070
uniprot id: W8SKN8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1294273:ROSELON RS09300
gene id: 1294273:ROSELON_RS09300
uniprot id: W8SP80
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1294273:ROSELON RS12985
gene id: 1294273:ROSELON_RS12985
uniprot id: W8SRD2
names: Function
names: Subcellular Location Annotation
messages: Could be a virulence factor.
messages: Secreted

1294273:ROSELON RS04695
gene id: 1294273:ROSELON_RS04695
uniprot id: W8SLK9
names: Similarity
messages: Belongs to the oxoprolinase family.

1294273:ROSELON RS04350
gene id: 1294273:ROSELON_RS04350
uniprot id: W8RQ82
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

1294273:ROSELON RS03525
gene id: 1294273:ROSELON_RS03525
uniprot id: W8SKW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1294273:ROSELON RS09130
gene id: 1294273:ROSELON_RS09130
uniprot id: W8RT32
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

1294273:ROSELON RS00280
gene id: 1294273:ROSELON_RS00280
uniprot id: W8S1D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

1294273:ROSELON RS07590
gene id: 1294273:ROSELON_RS07590
uniprot id: W8RS57
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1294273:ROSELON RS00335
gene id: 1294273:ROSELON_RS00335
uniprot id: W8RXJ8
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

1294273:ROSELON RS10665
gene id: 1294273:ROSELON_RS10665
uniprot id: W8S6T1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1294273:ROSELON RS15785
gene id: 1294273:ROSELON_RS15785
uniprot id: W8S9G9
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.

1294273:ROSELON RS01775
gene id: 1294273:ROSELON_RS01775
uniprot id: W8S263
names: Similarity
messages: Belongs to the GcvT family.

1294273:ROSELON RS14875
gene id: 1294273:ROSELON_RS14875
uniprot id: W8RWB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1294273:ROSELON RS08070
gene id: 1294273:ROSELON_RS08070
uniprot id: W8SNH7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

1294273:ROSELON RS01880
gene id: 1294273:ROSELON_RS01880
uniprot id: W8RPA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

1294273:ROSELON RS00815
gene id: 1294273:ROSELON_RS00815
uniprot id: W8RNB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1294273:ROSELON RS00395
gene id: 1294273:ROSELON_RS00395
uniprot id: W8SJ79
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1294273:ROSELON RS13795
gene id: 1294273:ROSELON_RS13795
uniprot id: W8S8E9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1294273:ROSELON RS04860
gene id: 1294273:ROSELON_RS04860
uniprot id: W8S003
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS11115
gene id: 1294273:ROSELON_RS11115
uniprot id: W8SQ77
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1294273:ROSELON RS05090
gene id: 1294273:ROSELON_RS05090
uniprot id: W8RQQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.
messages: Belongs to the antenna complex beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The core complex is formed by different alpha and beta chains, binding bacteriochlorophyll molecules, and arranged most probably in tetrameric structures disposed around the reaction center. The non-pigmented gamma chains may constitute additional components.

1294273:ROSELON RS07805
gene id: 1294273:ROSELON_RS07805
uniprot id: W8S1J7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1294273:ROSELON RS13655
gene id: 1294273:ROSELON_RS13655
uniprot id: W8S4R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

1294273:ROSELON RS10280
gene id: 1294273:ROSELON_RS10280
uniprot id: W8RTJ0
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS13690
gene id: 1294273:ROSELON_RS13690
uniprot id: W8RVI3
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1294273:ROSELON RS06645
gene id: 1294273:ROSELON_RS06645
uniprot id: W8RRJ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

1294273:ROSELON RS00080
gene id: 1294273:ROSELON_RS00080
uniprot id: W8RNB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1294273:ROSELON RS14915
gene id: 1294273:ROSELON_RS14915
uniprot id: W8S5I3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1294273:ROSELON RS12880
gene id: 1294273:ROSELON_RS12880
uniprot id: W8RUY3
names: Similarity
messages: Belongs to the DNA photolyase family.

1294273:ROSELON RS05610
gene id: 1294273:ROSELON_RS05610
uniprot id: W8RR79
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1294273:ROSELON RS04925
gene id: 1294273:ROSELON_RS04925
uniprot id: W8S3V9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1294273:ROSELON RS00360
gene id: 1294273:ROSELON_RS00360
uniprot id: W8RXK2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1294273:ROSELON RS02375
gene id: 1294273:ROSELON_RS02375
uniprot id: W8RYN6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1294273:ROSELON RS09160
gene id: 1294273:ROSELON_RS09160
uniprot id: W8RSX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1294273:ROSELON RS09175
gene id: 1294273:ROSELON_RS09175
uniprot id: W8S287
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1294273:ROSELON RS10590
gene id: 1294273:ROSELON_RS10590
uniprot id: W8SPY5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1294273:ROSELON RS01505
gene id: 1294273:ROSELON_RS01505
uniprot id: W8RY52
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1294273:ROSELON RS10800
gene id: 1294273:ROSELON_RS10800
uniprot id: W8S363
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1294273:ROSELON RS11230
gene id: 1294273:ROSELON_RS11230
uniprot id: W8S717
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1294273:ROSELON RS08435
gene id: 1294273:ROSELON_RS08435
uniprot id: W8SNQ0
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1294273:ROSELON RS01535
gene id: 1294273:ROSELON_RS01535
uniprot id: W8S208
names: Similarity
messages: Belongs to the ketopantoate reductase family.

1294273:ROSELON RS02005
gene id: 1294273:ROSELON_RS02005
uniprot id: W8RPD6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1294273:ROSELON RS00085
gene id: 1294273:ROSELON_RS00085
uniprot id: W8RN10
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.

1294273:ROSELON RS13265
gene id: 1294273:ROSELON_RS13265
uniprot id: W8SRI0
names: Caution
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1294273:ROSELON RS10660
gene id: 1294273:ROSELON_RS10660
uniprot id: W8SPZ6
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1294273:ROSELON RS00060
gene id: 1294273:ROSELON_RS00060
uniprot id: W8RN09
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1294273:ROSELON RS10640
gene id: 1294273:ROSELON_RS10640
uniprot id: W8S6S8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1294273:ROSELON RS13350
gene id: 1294273:ROSELON_RS13350
uniprot id: W8S4M0
names: Similarity
messages: Belongs to the LOG family.

1294273:ROSELON RS16865
gene id: 1294273:ROSELON_RS16865
uniprot id: W8RWY1
names: Similarity
messages: Belongs to the ArsC family.

1294273:ROSELON RS07050
gene id: 1294273:ROSELON_RS07050
uniprot id: W8RRT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1294273:ROSELON RS06760
gene id: 1294273:ROSELON_RS06760
uniprot id: W8S4S7
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1294273:ROSELON RS04065
gene id: 1294273:ROSELON_RS04065
uniprot id: W8S3D1
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1294273:ROSELON RS01175
gene id: 1294273:ROSELON_RS01175
uniprot id: W8RNX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1294273:ROSELON RS02445
gene id: 1294273:ROSELON_RS02445
uniprot id: W8RYP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1294273:ROSELON RS00905
gene id: 1294273:ROSELON_RS00905
uniprot id: W8RNS0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1294273:ROSELON RS08490
gene id: 1294273:ROSELON_RS08490
uniprot id: W8S5R4
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

1294273:ROSELON RS12275
gene id: 1294273:ROSELON_RS12275
uniprot id: W8S447
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1294273:ROSELON RS14770
gene id: 1294273:ROSELON_RS14770
uniprot id: W8S5F4
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1294273:ROSELON RS12970
gene id: 1294273:ROSELON_RS12970
uniprot id: W8S810
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. L-carnitine dehydrogenase subfamily.
messages: Catalyzes the NAD(+)-dependent oxidation of L-carnitine to 3-dehydrocarnitine.
messages: Cytoplasm
messages: Homodimer.

1294273:ROSELON RS03825
gene id: 1294273:ROSELON_RS03825
uniprot id: W8SL13
names: Similarity
messages: Belongs to the SDHAF4 family.

1294273:ROSELON RS12735
gene id: 1294273:ROSELON_RS12735
uniprot id: W8RUW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

1294273:ROSELON RS06175
gene id: 1294273:ROSELON_RS06175
uniprot id: W8SMD5
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

1294273:ROSELON RS16100
gene id: 1294273:ROSELON_RS16100
uniprot id: W8ST64
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1294273:ROSELON RS07255
gene id: 1294273:ROSELON_RS07255
uniprot id: W8RS08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1294273:ROSELON RS07350
gene id: 1294273:ROSELON_RS07350
uniprot id: W8RS22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1294273:ROSELON RS03190
gene id: 1294273:ROSELON_RS03190
uniprot id: W8SKQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1294273:ROSELON RS00445
gene id: 1294273:ROSELON_RS00445
uniprot id: W8RNI1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1294273:ROSELON RS15275
gene id: 1294273:ROSELON_RS15275
uniprot id: W8SSP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1294273:ROSELON RS02950
gene id: 1294273:ROSELON_RS02950
uniprot id: W8RYX5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1294273:ROSELON RS09180
gene id: 1294273:ROSELON_RS09180
uniprot id: W8RT41
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

1294273:ROSELON RS09315
gene id: 1294273:ROSELON_RS09315
uniprot id: W8RT00
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1294273:ROSELON RS09855
gene id: 1294273:ROSELON_RS09855
uniprot id: W8S2P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1294273:ROSELON RS01980
gene id: 1294273:ROSELON_RS01980
uniprot id: W8RPC9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1294273:ROSELON RS14040
gene id: 1294273:ROSELON_RS14040
uniprot id: W8S8J1
names: Similarity
messages: Belongs to the glycosyl hydrolase 68 family.

1294273:ROSELON RS16065
gene id: 1294273:ROSELON_RS16065
uniprot id: W8RWJ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1294273:ROSELON RS15020
gene id: 1294273:ROSELON_RS15020
uniprot id: W8SSK7
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1294273:ROSELON RS08145
gene id: 1294273:ROSELON_RS08145
uniprot id: W8S1Q8
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1294273:ROSELON RS09035
gene id: 1294273:ROSELON_RS09035
uniprot id: W8S258
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

1294273:ROSELON RS01470
gene id: 1294273:ROSELON_RS01470
uniprot id: W8RNP0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1294273:ROSELON RS04735
gene id: 1294273:ROSELON_RS04735
uniprot id: W8RQT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1294273:ROSELON RS14270
gene id: 1294273:ROSELON_RS14270
uniprot id: W8SS29
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1294273:ROSELON RS13440
gene id: 1294273:ROSELON_RS13440
uniprot id: W8RV80
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

1294273:ROSELON RS02055
gene id: 1294273:ROSELON_RS02055
uniprot id: W8RP13
names: Similarity
messages: Belongs to the YkuD family.

1294273:ROSELON RS10880
gene id: 1294273:ROSELON_RS10880
uniprot id: W8RTX7
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS17035
gene id: 1294273:ROSELON_RS17035
uniprot id: W8RX18
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS00325
gene id: 1294273:ROSELON_RS00325
uniprot id: W8SJ67
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1294273:ROSELON RS04035
gene id: 1294273:ROSELON_RS04035
uniprot id: W8SL50
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1294273:ROSELON RS13550
gene id: 1294273:ROSELON_RS13550
uniprot id: W8S4Q0
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1294273:ROSELON RS17135
gene id: 1294273:ROSELON_RS17135
uniprot id: W8S6L9
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS16545
gene id: 1294273:ROSELON_RS16545
uniprot id: W8RX50
names: Similarity
messages: Belongs to the UPF0262 family.

1294273:ROSELON RS03845
gene id: 1294273:ROSELON_RS03845
uniprot id: W8RPY0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1294273:ROSELON RS15980
gene id: 1294273:ROSELON_RS15980
uniprot id: W8S618
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1294273:ROSELON RS14815
gene id: 1294273:ROSELON_RS14815
uniprot id: W8S5G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1294273:ROSELON RS17130
gene id: 1294273:ROSELON_RS17130
uniprot id: W8SA94
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS14265
gene id: 1294273:ROSELON_RS14265
uniprot id: W8RVU9
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1294273:ROSELON RS14660
gene id: 1294273:ROSELON_RS14660
uniprot id: W8RW74
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1294273:ROSELON RS03980
gene id: 1294273:ROSELON_RS03980
uniprot id: W8RQ08
names: Similarity
messages: Belongs to the YkuD family.

1294273:ROSELON RS12225
gene id: 1294273:ROSELON_RS12225
uniprot id: W8S439
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1294273:ROSELON RS10935
gene id: 1294273:ROSELON_RS10935
uniprot id: W8SQ45
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1294273:ROSELON RS11565
gene id: 1294273:ROSELON_RS11565
uniprot id: W8SQI3
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1294273:ROSELON RS01955
gene id: 1294273:ROSELON_RS01955
uniprot id: W8RPC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1294273:ROSELON RS13560
gene id: 1294273:ROSELON_RS13560
uniprot id: W8SRN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

1294273:ROSELON RS07505
gene id: 1294273:ROSELON_RS07505
uniprot id: W8S1F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1294273:ROSELON RS02265
gene id: 1294273:ROSELON_RS02265
uniprot id: W8RPK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1294273:ROSELON RS12235
gene id: 1294273:ROSELON_RS12235
uniprot id: W8RUR9
names: Similarity
messages: Belongs to the HesB/IscA family.

1294273:ROSELON RS16015
gene id: 1294273:ROSELON_RS16015
uniprot id: W8RWV7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1294273:ROSELON RS07945
gene id: 1294273:ROSELON_RS07945
uniprot id: W8S1L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1294273:ROSELON RS16245
gene id: 1294273:ROSELON_RS16245
uniprot id: W8S667
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1294273:ROSELON RS06965
gene id: 1294273:ROSELON_RS06965
uniprot id: W8S4X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1294273:ROSELON RS16040
gene id: 1294273:ROSELON_RS16040
uniprot id: W8RWW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1294273:ROSELON RS14925
gene id: 1294273:ROSELON_RS14925
uniprot id: W8RWC1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1294273:ROSELON RS08930
gene id: 1294273:ROSELON_RS08930
uniprot id: W8S5Y9
names: Similarity
messages: Belongs to the histone deacetylase family.

1294273:ROSELON RS00795
gene id: 1294273:ROSELON_RS00795
uniprot id: W8SJE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1294273:ROSELON RS06770
gene id: 1294273:ROSELON_RS06770
uniprot id: W8RRT7
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS11630
gene id: 1294273:ROSELON_RS11630
uniprot id: W8RUC0
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS03145
gene id: 1294273:ROSELON_RS03145
uniprot id: W8S2Y0
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1294273:ROSELON RS02935
gene id: 1294273:ROSELON_RS02935
uniprot id: W8SKL6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1294273:ROSELON RS07540
gene id: 1294273:ROSELON_RS07540
uniprot id: W8SN99
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1294273:ROSELON RS03330
gene id: 1294273:ROSELON_RS03330
uniprot id: W8RPM9
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS10705
gene id: 1294273:ROSELON_RS10705
uniprot id: W8S6T7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1294273:ROSELON RS01605
gene id: 1294273:ROSELON_RS01605
uniprot id: W8RY66
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS10260
gene id: 1294273:ROSELON_RS10260
uniprot id: W8RTI6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1294273:ROSELON RS04730
gene id: 1294273:ROSELON_RS04730
uniprot id: W8RZY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1294273:ROSELON RS11925
gene id: 1294273:ROSELON_RS11925
uniprot id: W8RUG3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1294273:ROSELON RS07815
gene id: 1294273:ROSELON_RS07815
uniprot id: W8RS97
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1294273:ROSELON RS15755
gene id: 1294273:ROSELON_RS15755
uniprot id: W8SSZ2
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

1294273:ROSELON RS01065
gene id: 1294273:ROSELON_RS01065
uniprot id: W8SJK1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1294273:ROSELON RS07440
gene id: 1294273:ROSELON_RS07440
uniprot id: W8RS96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1294273:ROSELON RS03440
gene id: 1294273:ROSELON_RS03440
uniprot id: W8RZ58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1294273:ROSELON RS03380
gene id: 1294273:ROSELON_RS03380
uniprot id: W8RPN8
names: Similarity
messages: Belongs to the universal stress protein A family.

1294273:ROSELON RS16860
gene id: 1294273:ROSELON_RS16860
uniprot id: W8S6F7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane

1294273:ROSELON RS11635
gene id: 1294273:ROSELON_RS11635
uniprot id: W8SQJ9
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1294273:ROSELON RS06885
gene id: 1294273:ROSELON_RS06885
uniprot id: W8S112
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1294273:ROSELON RS05095
gene id: 1294273:ROSELON_RS05095
uniprot id: W8SLT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.
messages: Belongs to the antenna complex alpha subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The core complex is formed by different alpha and beta chains, binding bacteriochlorophyll molecules, and arranged most probably in tetrameric structures disposed around the reaction center. The non-pigmented gamma chains may constitute additional components.

1294273:ROSELON RS07725
gene id: 1294273:ROSELON_RS07725
uniprot id: W8S5D0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1294273:ROSELON RS04775
gene id: 1294273:ROSELON_RS04775
uniprot id: W8RZZ5
names: Similarity
messages: Belongs to the glutamate synthase family.

1294273:ROSELON RS16795
gene id: 1294273:ROSELON_RS16795
uniprot id: W8S6E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Periplasm

1294273:ROSELON RS09725
gene id: 1294273:ROSELON_RS09725
uniprot id: W8S2M0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1294273:ROSELON RS05340
gene id: 1294273:ROSELON_RS05340
uniprot id: W8S081
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS09560
gene id: 1294273:ROSELON_RS09560
uniprot id: W8RTA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.

1294273:ROSELON RS10100
gene id: 1294273:ROSELON_RS10100
uniprot id: W8SPQ8
names: Subcellular Location Annotation
messages: Cell membrane

1294273:ROSELON RS01370
gene id: 1294273:ROSELON_RS01370
uniprot id: W8RNL8
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1294273:ROSELON RS05155
gene id: 1294273:ROSELON_RS05155
uniprot id: W8RR05
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BchN/ChlN family.
messages: Binds 1 [4Fe-4S] cluster per heterodimer. The cluster is bound at the heterodimer interface by residues from both subunits.
messages: Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex.
messages: Protochlorophyllide reductase is composed of three subunits; BchL, BchN and BchB. Forms a heterotetramer of two BchB and two BchN subunits.

1294273:ROSELON RS04930
gene id: 1294273:ROSELON_RS04930
uniprot id: W8S012
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1294273:ROSELON RS15670
gene id: 1294273:ROSELON_RS15670
uniprot id: W8S5W9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1294273:ROSELON RS04175
gene id: 1294273:ROSELON_RS04175
uniprot id: W8SL76
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1294273:ROSELON RS10575
gene id: 1294273:ROSELON_RS10575
uniprot id: W8RTR9
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1294273:ROSELON RS02980
gene id: 1294273:ROSELON_RS02980
uniprot id: W8RPV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1294273:ROSELON RS04375
gene id: 1294273:ROSELON_RS04375
uniprot id: W8RQI3
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1294273:ROSELON RS07150
gene id: 1294273:ROSELON_RS07150
uniprot id: W8RS45
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1294273:ROSELON RS14885
gene id: 1294273:ROSELON_RS14885
uniprot id: W8S932
names: Subcellular Location Annotation
messages: Cell membrane

1294273:ROSELON RS15890
gene id: 1294273:ROSELON_RS15890
uniprot id: W8RWG0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1294273:ROSELON RS13775
gene id: 1294273:ROSELON_RS13775
uniprot id: W8S4U2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1294273:ROSELON RS06640
gene id: 1294273:ROSELON_RS06640
uniprot id: W8RRR7
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1294273:ROSELON RS06035
gene id: 1294273:ROSELON_RS06035
uniprot id: W8RR62
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1294273:ROSELON RS01555
gene id: 1294273:ROSELON_RS01555
uniprot id: W8RP38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Could be part of an ABC transporter complex.
messages: Membrane

1294273:ROSELON RS14315
gene id: 1294273:ROSELON_RS14315
uniprot id: W8RVW4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1294273:ROSELON RS07800
gene id: 1294273:ROSELON_RS07800
uniprot id: W8S5E1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1294273:ROSELON RS16620
gene id: 1294273:ROSELON_RS16620
uniprot id: W8RX65
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1294273:ROSELON RS17370
gene id: 1294273:ROSELON_RS17370
uniprot id: W8S434
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RTX toxin acyltransferase family.
messages: Cytoplasm
messages: Involved in fatty acylation of protoxin at internal lysine residues, thereby converting it to the active toxin.

1294273:ROSELON RS15940
gene id: 1294273:ROSELON_RS15940
uniprot id: W8RWU2
names: Similarity
messages: Belongs to the peptidase M24B family.

1294273:ROSELON RS13200
gene id: 1294273:ROSELON_RS13200
uniprot id: W8S853
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS16035
gene id: 1294273:ROSELON_RS16035
uniprot id: W8RWI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1294273:ROSELON RS13870
gene id: 1294273:ROSELON_RS13870
uniprot id: W8S8G1
names: Similarity
messages: Belongs to the HpcH/HpaI aldolase family.

1294273:ROSELON RS16045
gene id: 1294273:ROSELON_RS16045
uniprot id: W8ST54
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1294273:ROSELON RS16140
gene id: 1294273:ROSELON_RS16140
uniprot id: W8S653
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.

1294273:ROSELON RS16360
gene id: 1294273:ROSELON_RS16360
uniprot id: W8RWN7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1294273:ROSELON RS07340
gene id: 1294273:ROSELON_RS07340
uniprot id: W8S1C9
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1294273:ROSELON RS17650
gene id: 1294273:ROSELON_RS17650
uniprot id: W8RXL3
names: Similarity
messages: Belongs to the peptidase S33 family.

1294273:ROSELON RS07275
gene id: 1294273:ROSELON_RS07275
uniprot id: W8RS66
names: Similarity
messages: Belongs to the acylphosphatase family.

1294273:ROSELON RS16235
gene id: 1294273:ROSELON_RS16235
uniprot id: W8ST88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1294273:ROSELON RS03220
gene id: 1294273:ROSELON_RS03220
uniprot id: W8RPZ3
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

1294273:ROSELON RS08970
gene id: 1294273:ROSELON_RS08970
uniprot id: W8SP11
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

1294273:ROSELON RS09565
gene id: 1294273:ROSELON_RS09565
uniprot id: W8RT49
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1294273:ROSELON RS04815
gene id: 1294273:ROSELON_RS04815
uniprot id: W8SLP2
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS14155
gene id: 1294273:ROSELON_RS14155
uniprot id: W8RVK3
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1294273:ROSELON RS03740
gene id: 1294273:ROSELON_RS03740
uniprot id: W8RQ71
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

1294273:ROSELON RS02125
gene id: 1294273:ROSELON_RS02125
uniprot id: W8RYK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1294273:ROSELON RS06935
gene id: 1294273:ROSELON_RS06935
uniprot id: W8SMV7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1294273:ROSELON RS16455
gene id: 1294273:ROSELON_RS16455
uniprot id: W8STC1
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1294273:ROSELON RS14950
gene id: 1294273:ROSELON_RS14950
uniprot id: W8RWC4
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1294273:ROSELON RS08925
gene id: 1294273:ROSELON_RS08925
uniprot id: W8SP00
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1294273:ROSELON RS12455
gene id: 1294273:ROSELON_RS12455
uniprot id: W8SR40
names: Similarity
messages: Belongs to the GcvT family.

1294273:ROSELON RS11205
gene id: 1294273:ROSELON_RS11205
uniprot id: W8RU18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1294273:ROSELON RS15100
gene id: 1294273:ROSELON_RS15100
uniprot id: W8RW36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1294273:ROSELON RS13810
gene id: 1294273:ROSELON_RS13810
uniprot id: W8SRT6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1294273:ROSELON RS00665
gene id: 1294273:ROSELON_RS00665
uniprot id: W8RN90
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1294273:ROSELON RS09200
gene id: 1294273:ROSELON_RS09200
uniprot id: W8S636
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

1294273:ROSELON RS12575
gene id: 1294273:ROSELON_RS12575
uniprot id: W8S489
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1294273:ROSELON RS14790
gene id: 1294273:ROSELON_RS14790
uniprot id: W8S915
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

1294273:ROSELON RS08735
gene id: 1294273:ROSELON_RS08735
uniprot id: W8RSP4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1294273:ROSELON RS05320
gene id: 1294273:ROSELON_RS05320
uniprot id: W8RR26
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS06020
gene id: 1294273:ROSELON_RS06020
uniprot id: W8S0J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1294273:ROSELON RS06920
gene id: 1294273:ROSELON_RS06920
uniprot id: W8SMV0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1294273:ROSELON RS07840
gene id: 1294273:ROSELON_RS07840
uniprot id: W8RSA1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Cell inner membrane
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1294273:ROSELON RS03095
gene id: 1294273:ROSELON_RS03095
uniprot id: W8SKP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1294273:ROSELON RS15485
gene id: 1294273:ROSELON_RS15485
uniprot id: W8S5T4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1294273:ROSELON RS15095
gene id: 1294273:ROSELON_RS15095
uniprot id: W8S5L6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1294273:ROSELON RS05685
gene id: 1294273:ROSELON_RS05685
uniprot id: W8RR95
names: Similarity
messages: Belongs to the peptidase C40 family.

1294273:ROSELON RS14550
gene id: 1294273:ROSELON_RS14550
uniprot id: W8S8V2
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

1294273:ROSELON RS00090
gene id: 1294273:ROSELON_RS00090
uniprot id: W8SJ25
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1294273:ROSELON RS06980
gene id: 1294273:ROSELON_RS06980
uniprot id: W8SMX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1294273:ROSELON RS11665
gene id: 1294273:ROSELON_RS11665
uniprot id: W8S7B1
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1294273:ROSELON RS08265
gene id: 1294273:ROSELON_RS08265
uniprot id: W8S5M0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1294273:ROSELON RS07120
gene id: 1294273:ROSELON_RS07120
uniprot id: W8S164
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

1294273:ROSELON RS02675
gene id: 1294273:ROSELON_RS02675
uniprot id: W8RYT3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1294273:ROSELON RS08195
gene id: 1294273:ROSELON_RS08195
uniprot id: W8S5K7
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS17390
gene id: 1294273:ROSELON_RS17390
uniprot id: W8S0B8
names: Function
messages: Converts beta-D-mannuronic acid (M) to alpha-L-guluronic acid (G), producing a polymer with gel-forming capacity, required for the formation of the cyst coat.

1294273:ROSELON RS06095
gene id: 1294273:ROSELON_RS06095
uniprot id: W8RR77
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1294273:ROSELON RS01625
gene id: 1294273:ROSELON_RS01625
uniprot id: W8S225
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

1294273:ROSELON RS04090
gene id: 1294273:ROSELON_RS04090
uniprot id: W8S3D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

1294273:ROSELON RS05635
gene id: 1294273:ROSELON_RS05635
uniprot id: W8RR85
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1294273:ROSELON RS12460
gene id: 1294273:ROSELON_RS12460
uniprot id: W8S7T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.
messages: Membrane

1294273:ROSELON RS07045
gene id: 1294273:ROSELON_RS07045
uniprot id: W8RRZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1294273:ROSELON RS16145
gene id: 1294273:ROSELON_RS16145
uniprot id: W8RWK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Oligomer of 12 subunits arranged in the form of two hexameric ring.

1294273:ROSELON RS06450
gene id: 1294273:ROSELON_RS06450
uniprot id: W8RRF1
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1294273:ROSELON RS01425
gene id: 1294273:ROSELON_RS01425
uniprot id: W8RNM9
names: Subcellular Location Annotation
messages: Membrane

1294273:ROSELON RS03325
gene id: 1294273:ROSELON_RS03325
uniprot id: W8RQ10
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1294273:ROSELON RS07405
gene id: 1294273:ROSELON_RS07405
uniprot id: W8SN76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1294273:ROSELON RS01130
gene id: 1294273:ROSELON_RS01130
uniprot id: W8RNW5
names: Similarity
messages: Belongs to the UPF0276 family.

1294273:ROSELON RS02155
gene id: 1294273:ROSELON_RS02155
uniprot id: W8RPJ1
names: Function
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

1294273:ROSELON RS09775
gene id: 1294273:ROSELON_RS09775
uniprot id: W8RTE6
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1294273:ROSELON RS00270
gene id: 1294273:ROSELON_RS00270
uniprot id: W8RN36
names: Similarity
messages: Belongs to the peptidase M16 family.

1294273:ROSELON RS16460
gene id: 1294273:ROSELON_RS16460
uniprot id: W8S9T5
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1294273:ROSELON RS08340
gene id: 1294273:ROSELON_RS08340
uniprot id: W8S5N4
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1294273:ROSELON RS09430
gene id: 1294273:ROSELON_RS09430
uniprot id: W8RT83
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1294273:ROSELON RS06200
gene id: 1294273:ROSELON_RS06200
uniprot id: W8SMD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

1294273:ROSELON RS05860
gene id: 1294273:ROSELON_RS05860
uniprot id: W8SM69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1294273:ROSELON RS07450
gene id: 1294273:ROSELON_RS07450
uniprot id: W8SN83
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1294273:ROSELON RS06180
gene id: 1294273:ROSELON_RS06180
uniprot id: W8S4H9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1294273:ROSELON RS03345
gene id: 1294273:ROSELON_RS03345
uniprot id: W8RZ40
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1294273:ROSELON RS00275
gene id: 1294273:ROSELON_RS00275
uniprot id: W8SJ57
names: Similarity
messages: Belongs to the threonine synthase family.

1294273:ROSELON RS07480
gene id: 1294273:ROSELON_RS07480
uniprot id: W8S1E9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1294273:ROSELON RS12585
gene id: 1294273:ROSELON_RS12585
uniprot id: W8RUX3
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1294273:ROSELON RS04150
gene id: 1294273:ROSELON_RS04150
uniprot id: W8S3E9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1294273:ROSELON RS13330
gene id: 1294273:ROSELON_RS13330
uniprot id: W8RV63
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1294273:ROSELON RS10600
gene id: 1294273:ROSELON_RS10600
uniprot id: W8S318
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.