128944:AWM75 RS02705
gene id: 128944:AWM75_RS02705
uniprot id: A0A0X8FKH3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

128944:AWM75 RS06425
gene id: 128944:AWM75_RS06425
uniprot id: A0A109RGX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

128944:AWM75 RS05455
gene id: 128944:AWM75_RS05455
uniprot id: A0A120IAX6
names: Similarity
messages: Belongs to the EamA transporter family.

128944:AWM75 RS03130
gene id: 128944:AWM75_RS03130
uniprot id: A0A109RGQ3
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

128944:AWM75 RS01965
gene id: 128944:AWM75_RS01965
uniprot id: A0A0X8FK69
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

128944:AWM75 RS00350
gene id: 128944:AWM75_RS00350
uniprot id: A0A0X8FJK2
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

128944:AWM75 RS00780
gene id: 128944:AWM75_RS00780
uniprot id: A0A109RGK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Cell membrane
messages: Membrane
messages: N-acetylglucosaminyltransferase that catalyzes the polymerization of single monomer units of UDP-N-acetylglucosamine to produce the linear homomer poly-beta-1,6-N-acetyl-D-glucosamine (PNAG, also referred to as PIA), a biofilm adhesin polysaccharide. Requires IcaD for full activity.

128944:AWM75 RS05785
gene id: 128944:AWM75_RS05785
uniprot id: A0A0X8FLQ1
names: Subcellular Location Annotation
messages: Membrane

128944:AWM75 RS05675
gene id: 128944:AWM75_RS05675
uniprot id: A0A109RH44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Cell membrane
messages: Membrane

128944:AWM75 RS04545
gene id: 128944:AWM75_RS04545
uniprot id: A0A0X8FL41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

128944:AWM75 RS02230
gene id: 128944:AWM75_RS02230
uniprot id: A0A0X8FKB0
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

128944:AWM75 RS03115
gene id: 128944:AWM75_RS03115
uniprot id: A0A109RGW8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

128944:AWM75 RS00025
gene id: 128944:AWM75_RS00025
uniprot id: A0A0X8FJF9
names: Similarity
messages: Belongs to the peptidase M20A family.

128944:AWM75 RS00960
gene id: 128944:AWM75_RS00960
uniprot id: A0A109RGE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
messages: Membrane

128944:AWM75 RS05875
gene id: 128944:AWM75_RS05875
uniprot id: A0A0X8FLR2
names: Similarity
messages: Belongs to the glycosyl hydrolase 73 family.

128944:AWM75 RS06415
gene id: 128944:AWM75_RS06415
uniprot id: A0A109RHC1
names: Similarity
messages: Belongs to the thioester dehydratase family. FabZ subfamily.

128944:AWM75 RS05955
gene id: 128944:AWM75_RS05955
uniprot id: A0A0X8FLK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

128944:AWM75 RS05380
gene id: 128944:AWM75_RS05380
uniprot id: A0A109RI11
names: Similarity
messages: Belongs to the UPF0340 family.

128944:AWM75 RS01550
gene id: 128944:AWM75_RS01550
uniprot id: A0A0X8FK25
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

128944:AWM75 RS04825
gene id: 128944:AWM75_RS04825
uniprot id: A0A0X8FLD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

128944:AWM75 RS07085
gene id: 128944:AWM75_RS07085
uniprot id: A0A109RH76
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

128944:AWM75 RS08485
gene id: 128944:AWM75_RS08485
uniprot id: A0A0X8FMH0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

128944:AWM75 RS00360
gene id: 128944:AWM75_RS00360
uniprot id: A0A0X8FJP1
names: Subcellular Location Annotation
messages: Membrane

128944:AWM75 RS01675
gene id: 128944:AWM75_RS01675
uniprot id: A0A0X8FK44
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

128944:AWM75 RS03680
gene id: 128944:AWM75_RS03680
uniprot id: A0A120IAU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

128944:AWM75 RS00010
gene id: 128944:AWM75_RS00010
uniprot id: A0A109RHE8
names: Subcellular Location Annotation
messages: Membrane

128944:AWM75 RS01745
gene id: 128944:AWM75_RS01745
uniprot id: A0A0X8FKL4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

128944:AWM75 RS05415
gene id: 128944:AWM75_RS05415
uniprot id: A0A0X8FLE4
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

128944:AWM75 RS03975
gene id: 128944:AWM75_RS03975
uniprot id: A0A0X8FLD2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

128944:AWM75 RS06740
gene id: 128944:AWM75_RS06740
uniprot id: A0A0X8FN36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Cytoplasm
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.

128944:AWM75 RS06255
gene id: 128944:AWM75_RS06255
uniprot id: A0A0X8FMX3
names: Similarity
messages: Belongs to the thioester dehydratase family. FabZ subfamily.

128944:AWM75 RS01700
gene id: 128944:AWM75_RS01700
uniprot id: A0A109RHL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

128944:AWM75 RS00455
gene id: 128944:AWM75_RS00455
uniprot id: A0A0X8FK32
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

128944:AWM75 RS04065
gene id: 128944:AWM75_RS04065
uniprot id: A0A0X8FM84
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

128944:AWM75 RS04620
gene id: 128944:AWM75_RS04620
uniprot id: A0A0X8FLA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

128944:AWM75 RS00140
gene id: 128944:AWM75_RS00140
uniprot id: A0A0X8FJY8
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

128944:AWM75 RS02315
gene id: 128944:AWM75_RS02315
uniprot id: A0A0X8FKB2
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

128944:AWM75 RS08270
gene id: 128944:AWM75_RS08270
uniprot id: A0A0X8FMG1
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

128944:AWM75 RS04505
gene id: 128944:AWM75_RS04505
uniprot id: A0A120IAV7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

128944:AWM75 RS05555
gene id: 128944:AWM75_RS05555
uniprot id: A0A0X8FLM2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

128944:AWM75 RS07565
gene id: 128944:AWM75_RS07565
uniprot id: A0A109RH94
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

128944:AWM75 RS02360
gene id: 128944:AWM75_RS02360
uniprot id: A0A109RGC1
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

128944:AWM75 RS06685
gene id: 128944:AWM75_RS06685
uniprot id: A0A109RHZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

128944:AWM75 RS00370
gene id: 128944:AWM75_RS00370
uniprot id: A0A0X8FJM6
names: Function
names: Similarity
messages: Belongs to the ArsC family.
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

128944:AWM75 RS01005
gene id: 128944:AWM75_RS01005
uniprot id: A0A0X8FJV3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

128944:AWM75 RS05115
gene id: 128944:AWM75_RS05115
uniprot id: A0A109RH73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

128944:AWM75 RS02830
gene id: 128944:AWM75_RS02830
uniprot id: A0A109RGF9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

128944:AWM75 RS08235
gene id: 128944:AWM75_RS08235
uniprot id: A0A0X8FMD0
names: Subcellular Location Annotation
messages: Membrane

128944:AWM75 RS03145
gene id: 128944:AWM75_RS03145
uniprot id: A0A0X8FKT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

128944:AWM75 RS04735
gene id: 128944:AWM75_RS04735
uniprot id: A0A0X8FL66
names: Similarity
messages: Belongs to the ParB family.

128944:AWM75 RS03705
gene id: 128944:AWM75_RS03705
uniprot id: A0A0X8FKU1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

128944:AWM75 RS03170
gene id: 128944:AWM75_RS03170
uniprot id: A0A0X8FKM7
names: Subcellular Location Annotation
messages: Membrane

128944:AWM75 RS00465
gene id: 128944:AWM75_RS00465
uniprot id: A0A0X8FJM5
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

128944:AWM75 RS02700
gene id: 128944:AWM75_RS02700
uniprot id: A0A0X8FKG0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

128944:AWM75 RS05580
gene id: 128944:AWM75_RS05580
uniprot id: A0A0X8FLG3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

128944:AWM75 RS03140
gene id: 128944:AWM75_RS03140
uniprot id: A0A109RHM5
names: Subcellular Location Annotation
messages: Membrane

128944:AWM75 RS07325
gene id: 128944:AWM75_RS07325
uniprot id: A0A0X8FMG3
names: Subcellular Location Annotation
messages: Membrane

128944:AWM75 RS02335
gene id: 128944:AWM75_RS02335
uniprot id: A0A0X8FKC7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

128944:AWM75 RS07725
gene id: 128944:AWM75_RS07725
uniprot id: A0A109RHG9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

128944:AWM75 RS05375
gene id: 128944:AWM75_RS05375
uniprot id: A0A109RGZ4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

128944:AWM75 RS02010
gene id: 128944:AWM75_RS02010
uniprot id: A0A0X8FK86
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

128944:AWM75 RS00020
gene id: 128944:AWM75_RS00020
uniprot id: A0A0X8FJQ5
names: Subcellular Location Annotation
messages: Membrane

128944:AWM75 RS04420
gene id: 128944:AWM75_RS04420
uniprot id: A0A109RH07
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

128944:AWM75 RS06185
gene id: 128944:AWM75_RS06185
uniprot id: A0A109RGW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

128944:AWM75 RS04395
gene id: 128944:AWM75_RS04395
uniprot id: A0A0X8FL16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

128944:AWM75 RS07910
gene id: 128944:AWM75_RS07910
uniprot id: A0A0X8FMD4
names: Similarity
messages: Belongs to the UPF0047 family.

128944:AWM75 RS01595
gene id: 128944:AWM75_RS01595
uniprot id: A0A109RGJ5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

128944:AWM75 RS00930
gene id: 128944:AWM75_RS00930
uniprot id: A0A0X8FKA3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

128944:AWM75 RS02000
gene id: 128944:AWM75_RS02000
uniprot id: A0A0X8FK71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0154 family.
messages: Membrane

128944:AWM75 RS06710
gene id: 128944:AWM75_RS06710
uniprot id: A0A0X8FLU7
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

128944:AWM75 RS03710
gene id: 128944:AWM75_RS03710
uniprot id: A0A0X8FKU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.

128944:AWM75 RS02665
gene id: 128944:AWM75_RS02665
uniprot id: A0A109RHQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

128944:AWM75 RS04325
gene id: 128944:AWM75_RS04325
uniprot id: A0A0X8FL10
names: Cofactor
messages: Binds 1 zinc ion per subunit.

128944:AWM75 RS02490
gene id: 128944:AWM75_RS02490
uniprot id: A0A109RGS2
names: Similarity
messages: Belongs to the thioester dehydratase family. FabZ subfamily.

128944:AWM75 RS00300
gene id: 128944:AWM75_RS00300
uniprot id: A0A0X8FJK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

128944:AWM75 RS02880
gene id: 128944:AWM75_RS02880
uniprot id: A0A0X8FMH6
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

128944:AWM75 RS04000
gene id: 128944:AWM75_RS04000
uniprot id: A0A109RGQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

128944:AWM75 RS00130
gene id: 128944:AWM75_RS00130
uniprot id: A0A0X8FJJ9
names: Similarity
messages: Belongs to the fabD family.

128944:AWM75 RS02320
gene id: 128944:AWM75_RS02320
uniprot id: A0A0X8FKC3
names: Similarity
messages: Belongs to the FGGY kinase family.

128944:AWM75 RS05120
gene id: 128944:AWM75_RS05120
uniprot id: A0A0X8FMK0
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

128944:AWM75 RS01930
gene id: 128944:AWM75_RS01930
uniprot id: A0A109RGR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

128944:AWM75 RS03740
gene id: 128944:AWM75_RS03740
uniprot id: A0A0X8FKV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

128944:AWM75 RS00915
gene id: 128944:AWM75_RS00915
uniprot id: A0A0X8FJV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

128944:AWM75 RS06680
gene id: 128944:AWM75_RS06680
uniprot id: A0A109RI64
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

128944:AWM75 RS02690
gene id: 128944:AWM75_RS02690
uniprot id: A0A0X8FKG9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

128944:AWM75 RS04090
gene id: 128944:AWM75_RS04090
uniprot id: A0A109RHQ7
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

128944:AWM75 RS07235
gene id: 128944:AWM75_RS07235
uniprot id: A0A0X8FLZ5
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

128944:AWM75 RS04725
gene id: 128944:AWM75_RS04725
uniprot id: A0A0X8FL72
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

128944:AWM75 RS05885
gene id: 128944:AWM75_RS05885
uniprot id: A0A0X8FLL5
names: Similarity
messages: Belongs to the peptidase C40 family.

128944:AWM75 RS02465
gene id: 128944:AWM75_RS02465
uniprot id: A0A0X8FKD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

128944:AWM75 RS01735
gene id: 128944:AWM75_RS01735
uniprot id: A0A0X8FK49
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

128944:AWM75 RS05225
gene id: 128944:AWM75_RS05225
uniprot id: A0A0X8FLI1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

128944:AWM75 RS01585
gene id: 128944:AWM75_RS01585
uniprot id: A0A0X8FKJ4
names: Similarity
messages: Belongs to the cycloisomerase 2 family.

128944:AWM75 RS02305
gene id: 128944:AWM75_RS02305
uniprot id: A0A0X8FKC6
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

128944:AWM75 RS03220
gene id: 128944:AWM75_RS03220
uniprot id: A0A120IAT4
names: Function
names: Similarity
messages: Belongs to the CpsD/CapB family.
messages: Involved in the regulation of capsular polysaccharide biosynthesis. Autophosphorylation of CpsD attenuates its activity and reduces the level of encapsulation. May be part of a complex that directs the coordinated polymerization and export to the cell surface of the capsular polysaccharide.

128944:AWM75 RS06690
gene id: 128944:AWM75_RS06690
uniprot id: A0A0X8FLZ9
names: Similarity
messages: Belongs to the CinA family.

128944:AWM75 RS02995
gene id: 128944:AWM75_RS02995
uniprot id: A0A0X8FKQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

128944:AWM75 RS02660
gene id: 128944:AWM75_RS02660
uniprot id: A0A109RGJ4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

128944:AWM75 RS00210
gene id: 128944:AWM75_RS00210
uniprot id: A0A0X8FJL2
names: Subcellular Location Annotation
messages: Cytoplasm

128944:AWM75 RS03275
gene id: 128944:AWM75_RS03275
uniprot id: A0A109RGQ5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

128944:AWM75 RS08875
gene id: 128944:AWM75_RS08875
uniprot id: A0A109RGC5
names: Subcellular Location Annotation
messages: Membrane

128944:AWM75 RS05990
gene id: 128944:AWM75_RS05990
uniprot id: A0A0X8FLN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

128944:AWM75 RS00740
gene id: 128944:AWM75_RS00740
uniprot id: A0A0X8FJQ9
names: Similarity
messages: Belongs to the OsmC/Ohr family.

128944:AWM75 RS07055
gene id: 128944:AWM75_RS07055
uniprot id: A0A0X8FLY4
names: Subcellular Location Annotation
messages: Cytoplasm

128944:AWM75 RS01915
gene id: 128944:AWM75_RS01915
uniprot id: A0A0X8FK60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

128944:AWM75 RS06695
gene id: 128944:AWM75_RS06695
uniprot id: A0A0X8FLU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

128944:AWM75 RS00235
gene id: 128944:AWM75_RS00235
uniprot id: A0A0X8FKX2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

128944:AWM75 RS00270
gene id: 128944:AWM75_RS00270
uniprot id: A0A0X8FJJ3
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

128944:AWM75 RS02580
gene id: 128944:AWM75_RS02580
uniprot id: A0A120IAR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

128944:AWM75 RS01275
gene id: 128944:AWM75_RS01275
uniprot id: A0A120IAP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

128944:AWM75 RS01310
gene id: 128944:AWM75_RS01310
uniprot id: A0A0X8FK10
names: Function
messages: Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase.

128944:AWM75 RS02235
gene id: 128944:AWM75_RS02235
uniprot id: A0A0X8FKA0
names: Activity Regulation
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), including enzyme I, and histidine-containing protein (HPr) are required for the phosphorylation, which leads to the activation of the enzyme.

128944:AWM75 RS03510
gene id: 128944:AWM75_RS03510
uniprot id: A0A0X8FKS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

128944:AWM75 RS03605
gene id: 128944:AWM75_RS03605
uniprot id: A0A109RGS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

128944:AWM75 RS02770
gene id: 128944:AWM75_RS02770
uniprot id: A0A0X8FKH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

128944:AWM75 RS08205
gene id: 128944:AWM75_RS08205
uniprot id: A0A0X8FMB1
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

128944:AWM75 RS06675
gene id: 128944:AWM75_RS06675
uniprot id: A0A109RH67
names: Similarity
messages: Belongs to the acylphosphatase family.

128944:AWM75 RS02760
gene id: 128944:AWM75_RS02760
uniprot id: A0A0X8FKG7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

128944:AWM75 RS02940
gene id: 128944:AWM75_RS02940
uniprot id: A0A0X8FKJ1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

128944:AWM75 RS06550
gene id: 128944:AWM75_RS06550
uniprot id: A0A0X8FLT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

128944:AWM75 RS06325
gene id: 128944:AWM75_RS06325
uniprot id: A0A109RH23
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

128944:AWM75 RS00280
gene id: 128944:AWM75_RS00280
uniprot id: A0A0X8FJN8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

128944:AWM75 RS08125
gene id: 128944:AWM75_RS08125
uniprot id: A0A120IB29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

128944:AWM75 RS03480
gene id: 128944:AWM75_RS03480
uniprot id: A0A0X8FKS1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

128944:AWM75 RS03150
gene id: 128944:AWM75_RS03150
uniprot id: A0A0X8FKM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

128944:AWM75 RS05790
gene id: 128944:AWM75_RS05790
uniprot id: A0A0X8FLI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

128944:AWM75 RS06315
gene id: 128944:AWM75_RS06315
uniprot id: A0A0X8FM56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

128944:AWM75 RS04150
gene id: 128944:AWM75_RS04150
uniprot id: A0A0X8FM94
names: Similarity
messages: Belongs to the ClpA/ClpB family.

128944:AWM75 RS06700
gene id: 128944:AWM75_RS06700
uniprot id: A0A0X8FLV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

128944:AWM75 RS08080
gene id: 128944:AWM75_RS08080
uniprot id: A0A0X8FMB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

128944:AWM75 RS07815
gene id: 128944:AWM75_RS07815
uniprot id: A0A120IB22
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

128944:AWM75 RS02020
gene id: 128944:AWM75_RS02020
uniprot id: A0A0X8FLI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

128944:AWM75 RS03300
gene id: 128944:AWM75_RS03300
uniprot id: A0A109RGE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

128944:AWM75 RS07490
gene id: 128944:AWM75_RS07490
uniprot id: A0A109RHG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

128944:AWM75 RS07485
gene id: 128944:AWM75_RS07485
uniprot id: A0A0X8FM48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

128944:AWM75 RS04535
gene id: 128944:AWM75_RS04535
uniprot id: A0A0X8FL54
names: Subcellular Location Annotation
messages: Membrane

128944:AWM75 RS02860
gene id: 128944:AWM75_RS02860
uniprot id: A0A0X8FKI3
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

128944:AWM75 RS02195
gene id: 128944:AWM75_RS02195
uniprot id: A0A109RGH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane

128944:AWM75 RS02410
gene id: 128944:AWM75_RS02410
uniprot id: A0A0X8FKD6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

128944:AWM75 RS06235
gene id: 128944:AWM75_RS06235
uniprot id: A0A0X8FLM9
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

128944:AWM75 RS02380
gene id: 128944:AWM75_RS02380
uniprot id: A0A0X8FKD3
names: Similarity
messages: Belongs to the glycosyl hydrolase 73 family.

128944:AWM75 RS06640
gene id: 128944:AWM75_RS06640
uniprot id: A0A0X8FLT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

128944:AWM75 RS05250
gene id: 128944:AWM75_RS05250
uniprot id: A0A0X8FLD1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

128944:AWM75 RS02090
gene id: 128944:AWM75_RS02090
uniprot id: A0A0X8FK97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

128944:AWM75 RS07715
gene id: 128944:AWM75_RS07715
uniprot id: A0A0X8FML3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

128944:AWM75 RS07360
gene id: 128944:AWM75_RS07360
uniprot id: A0A0X8FN00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

128944:AWM75 RS07700
gene id: 128944:AWM75_RS07700
uniprot id: A0A0X8FMB1
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

128944:AWM75 RS04110
gene id: 128944:AWM75_RS04110
uniprot id: A0A0X8FL04
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

128944:AWM75 RS04510
gene id: 128944:AWM75_RS04510
uniprot id: A0A109RGS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

128944:AWM75 RS07555
gene id: 128944:AWM75_RS07555
uniprot id: A0A0X8FMJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

128944:AWM75 RS05690
gene id: 128944:AWM75_RS05690
uniprot id: A0A120IAY1
names: Similarity
messages: Belongs to the OsmC/Ohr family.

128944:AWM75 RS06360
gene id: 128944:AWM75_RS06360
uniprot id: A0A0X8FLP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

128944:AWM75 RS01190
gene id: 128944:AWM75_RS01190
uniprot id: A0A109RGJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

128944:AWM75 RS06440
gene id: 128944:AWM75_RS06440
uniprot id: A0A109RI53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

128944:AWM75 RS03090
gene id: 128944:AWM75_RS03090
uniprot id: A0A0X8FKL1
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

128944:AWM75 RS06725
gene id: 128944:AWM75_RS06725
uniprot id: A0A0X8FMB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

128944:AWM75 RS07630
gene id: 128944:AWM75_RS07630
uniprot id: A0A0X8FM40
names: Subcellular Location Annotation
messages: Membrane

128944:AWM75 RS06915
gene id: 128944:AWM75_RS06915
uniprot id: A0A0X8FM26
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

128944:AWM75 RS02610
gene id: 128944:AWM75_RS02610
uniprot id: A0A0X8FKG3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

128944:AWM75 RS02030
gene id: 128944:AWM75_RS02030
uniprot id: A0A120IAQ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

128944:AWM75 RS06420
gene id: 128944:AWM75_RS06420
uniprot id: A0A0X8FMZ2
names: Similarity
messages: Belongs to the acetyltransferase family.

128944:AWM75 RS08045
gene id: 128944:AWM75_RS08045
uniprot id: A0A0X8FNI7
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

128944:AWM75 RS07330
gene id: 128944:AWM75_RS07330
uniprot id: A0A0X8FM28
names: Similarity
messages: Belongs to the serine/threonine dehydratase family. DsdA subfamily.

128944:AWM75 RS06750
gene id: 128944:AWM75_RS06750
uniprot id: A0A120IAZ8
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

128944:AWM75 RS03535
gene id: 128944:AWM75_RS03535
uniprot id: A0A109RGE8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

128944:AWM75 RS06645
gene id: 128944:AWM75_RS06645
uniprot id: A0A0X8FMA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EzrA family.
messages: Cell membrane
messages: Membrane
messages: Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization.

128944:AWM75 RS07505
gene id: 128944:AWM75_RS07505
uniprot id: A0A109RH93
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

128944:AWM75 RS05395
gene id: 128944:AWM75_RS05395
uniprot id: A0A0X8FLE0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

128944:AWM75 RS01730
gene id: 128944:AWM75_RS01730
uniprot id: A0A0X8FK42
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

128944:AWM75 RS06350
gene id: 128944:AWM75_RS06350
uniprot id: A0A109RGT6
names: Similarity
messages: Belongs to the MecA family.

128944:AWM75 RS04605
gene id: 128944:AWM75_RS04605
uniprot id: A0A109RGV9
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

128944:AWM75 RS04235
gene id: 128944:AWM75_RS04235
uniprot id: A0A0X8FL05
names: Similarity
messages: Belongs to the ABC transporter superfamily.

128944:AWM75 RS01135
gene id: 128944:AWM75_RS01135
uniprot id: A0A109RG69
names: Subcellular Location Annotation
messages: Membrane

128944:AWM75 RS03990
gene id: 128944:AWM75_RS03990
uniprot id: A0A0X8FM74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

128944:AWM75 RS08035
gene id: 128944:AWM75_RS08035
uniprot id: A0A0X8FMB8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

128944:AWM75 RS00645
gene id: 128944:AWM75_RS00645
uniprot id: A0A109RGD4
names: Similarity
messages: Belongs to the peptidase M13 family.

128944:AWM75 RS03925
gene id: 128944:AWM75_RS03925
uniprot id: A0A120IAU7
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

128944:AWM75 RS05195
gene id: 128944:AWM75_RS05195
uniprot id: A0A0X8FML4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

128944:AWM75 RS03745
gene id: 128944:AWM75_RS03745
uniprot id: A0A109RGS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

128944:AWM75 RS07130
gene id: 128944:AWM75_RS07130
uniprot id: A0A0X8FLY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

128944:AWM75 RS05370
gene id: 128944:AWM75_RS05370
uniprot id: A0A109RGT0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

128944:AWM75 RS03520
gene id: 128944:AWM75_RS03520
uniprot id: A0A0X8FM20
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

128944:AWM75 RS04640
gene id: 128944:AWM75_RS04640
uniprot id: A0A109RH86
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

128944:AWM75 RS07245
gene id: 128944:AWM75_RS07245
uniprot id: A0A0X8FM19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

128944:AWM75 RS06715
gene id: 128944:AWM75_RS06715
uniprot id: A0A0X8FLT9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

128944:AWM75 RS04040
gene id: 128944:AWM75_RS04040
uniprot id: A0A0X8FKZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

128944:AWM75 RS04210
gene id: 128944:AWM75_RS04210
uniprot id: A0A0X8FL58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

128944:AWM75 RS03315
gene id: 128944:AWM75_RS03315
uniprot id: A0A0X8FKN7
names: Similarity
messages: Belongs to the UPF0178 family.

128944:AWM75 RS06355
gene id: 128944:AWM75_RS06355
uniprot id: A0A0X8FLV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArsC family. Spx subfamily.
messages: Cytoplasm
messages: Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes. Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase (RNAP). This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator.
messages: Interacts with the C-terminal domain of the alpha subunit of the RNAP.

128944:AWM75 RS02965
gene id: 128944:AWM75_RS02965
uniprot id: A0A109RGU1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

128944:AWM75 RS07205
gene id: 128944:AWM75_RS07205
uniprot id: A0A0X8FM46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

128944:AWM75 RS06260
gene id: 128944:AWM75_RS06260
uniprot id: A0A120IAZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

128944:AWM75 RS06390
gene id: 128944:AWM75_RS06390
uniprot id: A0A0X8FLP8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

128944:AWM75 RS06825
gene id: 128944:AWM75_RS06825
uniprot id: A0A109RH18
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

128944:AWM75 RS08855
gene id: 128944:AWM75_RS08855
uniprot id: A0A0X8FM09
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

128944:AWM75 RS05815
gene id: 128944:AWM75_RS05815
uniprot id: A0A0X8FLJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

128944:AWM75 RS05055
gene id: 128944:AWM75_RS05055
uniprot id: A0A109RGU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

128944:AWM75 RS04430
gene id: 128944:AWM75_RS04430
uniprot id: A0A120IAV9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

128944:AWM75 RS04140
gene id: 128944:AWM75_RS04140
uniprot id: A0A0X8FL06
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

128944:AWM75 RS00160
gene id: 128944:AWM75_RS00160
uniprot id: A0A120IAL7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

128944:AWM75 RS03590
gene id: 128944:AWM75_RS03590
uniprot id: A0A109RGZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

128944:AWM75 RS01230
gene id: 128944:AWM75_RS01230
uniprot id: A0A0X8FJZ9
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

128944:AWM75 RS00325
gene id: 128944:AWM75_RS00325
uniprot id: A0A120IAM4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

128944:AWM75 RS03800
gene id: 128944:AWM75_RS03800
uniprot id: A0A0X8FKV6
names: Subcellular Location Annotation
messages: Membrane

128944:AWM75 RS02375
gene id: 128944:AWM75_RS02375
uniprot id: A0A0X8FKB8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

128944:AWM75 RS04610
gene id: 128944:AWM75_RS04610
uniprot id: A0A109RHY3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

128944:AWM75 RS03410
gene id: 128944:AWM75_RS03410
uniprot id: A0A0X8FKQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

128944:AWM75 RS04005
gene id: 128944:AWM75_RS04005
uniprot id: A0A109RGG6
names: Similarity
messages: Belongs to the UPF0213 family.

128944:AWM75 RS00395
gene id: 128944:AWM75_RS00395
uniprot id: A0A0X8FKY9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

128944:AWM75 RS00920
gene id: 128944:AWM75_RS00920
uniprot id: A0A0X8FJU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

128944:AWM75 RS02035
gene id: 128944:AWM75_RS02035
uniprot id: A0A120IAR0
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
messages: Homohexamer.

128944:AWM75 RS05130
gene id: 128944:AWM75_RS05130
uniprot id: A0A109RGY3
names: Similarity
messages: Belongs to the IMPACT family.

128944:AWM75 RS01975
gene id: 128944:AWM75_RS01975
uniprot id: A0A0X8FK82
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

128944:AWM75 RS03565
gene id: 128944:AWM75_RS03565
uniprot id: A0A0X8FKR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

128944:AWM75 RS06590
gene id: 128944:AWM75_RS06590
uniprot id: A0A120IB01
names: Subcellular Location Annotation
messages: Cytoplasm

128944:AWM75 RS05235
gene id: 128944:AWM75_RS05235
uniprot id: A0A0X8FLB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

128944:AWM75 RS06305
gene id: 128944:AWM75_RS06305
uniprot id: A0A0X8FLP0
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

128944:AWM75 RS00400
gene id: 128944:AWM75_RS00400
uniprot id: A0A120IAM3
names: Subcellular Location Annotation
messages: Membrane

128944:AWM75 RS03200
gene id: 128944:AWM75_RS03200
uniprot id: A0A0X8FLY1
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

128944:AWM75 RS01165
gene id: 128944:AWM75_RS01165
uniprot id: A0A0X8FJX5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

128944:AWM75 RS01565
gene id: 128944:AWM75_RS01565
uniprot id: A0A0X8FK28
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

128944:AWM75 RS06905
gene id: 128944:AWM75_RS06905
uniprot id: A0A109RI73
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

128944:AWM75 RS04680
gene id: 128944:AWM75_RS04680
uniprot id: A0A120IAW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

128944:AWM75 RS03225
gene id: 128944:AWM75_RS03225
uniprot id: A0A0X8FKU3
names: Subcellular Location Annotation
messages: Membrane

128944:AWM75 RS07255
gene id: 128944:AWM75_RS07255
uniprot id: A0A0X8FN84
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

128944:AWM75 RS07535
gene id: 128944:AWM75_RS07535
uniprot id: A0A0X8FM43
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

128944:AWM75 RS04305
gene id: 128944:AWM75_RS04305
uniprot id: A0A0X8FL24
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

128944:AWM75 RS06735
gene id: 128944:AWM75_RS06735
uniprot id: A0A109RH64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

128944:AWM75 RS02290
gene id: 128944:AWM75_RS02290
uniprot id: A0A120IAR4
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

128944:AWM75 RS01285
gene id: 128944:AWM75_RS01285
uniprot id: A0A120IAP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

128944:AWM75 RS03120
gene id: 128944:AWM75_RS03120
uniprot id: A0A0X8FLX1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

128944:AWM75 RS00390
gene id: 128944:AWM75_RS00390
uniprot id: A0A109RGC0
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

128944:AWM75 RS08370
gene id: 128944:AWM75_RS08370
uniprot id: A0A109RH58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

128944:AWM75 RS05320
gene id: 128944:AWM75_RS05320
uniprot id: A0A0X8FLE6
names: Subcellular Location Annotation
messages: Membrane

128944:AWM75 RS04695
gene id: 128944:AWM75_RS04695
uniprot id: A0A109RHE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

128944:AWM75 RS02615
gene id: 128944:AWM75_RS02615
uniprot id: A0A0X8FKF8
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

128944:AWM75 RS02500
gene id: 128944:AWM75_RS02500
uniprot id: A0A120IAS0
names: Similarity
messages: Belongs to the DtxR/MntR family.

128944:AWM75 RS05545
gene id: 128944:AWM75_RS05545
uniprot id: A0A109RGL8
names: Subcellular Location Annotation
messages: Membrane

128944:AWM75 RS07185
gene id: 128944:AWM75_RS07185
uniprot id: A0A120IB11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

128944:AWM75 RS08455
gene id: 128944:AWM75_RS08455
uniprot id: A0A109RIC2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

128944:AWM75 RS00710
gene id: 128944:AWM75_RS00710
uniprot id: A0A0X8FL31
names: Similarity
messages: Belongs to the PemK/MazF family.

128944:AWM75 RS05365
gene id: 128944:AWM75_RS05365
uniprot id: A0A0X8FMN0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

128944:AWM75 RS06785
gene id: 128944:AWM75_RS06785
uniprot id: A0A0X8FLV4
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

128944:AWM75 RS05270
gene id: 128944:AWM75_RS05270
uniprot id: A0A0X8FLT3
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

128944:AWM75 RS04700
gene id: 128944:AWM75_RS04700
uniprot id: A0A109RID2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.

128944:AWM75 RS00445
gene id: 128944:AWM75_RS00445
uniprot id: A0A0X8FJP0
names: Similarity
messages: Belongs to the pyruvate kinase family.

128944:AWM75 RS00345
gene id: 128944:AWM75_RS00345
uniprot id: A0A0X8FJT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

128944:AWM75 RS04275
gene id: 128944:AWM75_RS04275
uniprot id: A0A109RGR8
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

128944:AWM75 RS03455
gene id: 128944:AWM75_RS03455
uniprot id: A0A120IAU0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

128944:AWM75 RS01305
gene id: 128944:AWM75_RS01305
uniprot id: A0A0X8FK11
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

128944:AWM75 RS02430
gene id: 128944:AWM75_RS02430
uniprot id: A0A109RGI3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

128944:AWM75 RS04165
gene id: 128944:AWM75_RS04165
uniprot id: A0A120IAW0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

128944:AWM75 RS01650
gene id: 128944:AWM75_RS01650
uniprot id: A0A0X8FK48
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

128944:AWM75 RS01425
gene id: 128944:AWM75_RS01425
uniprot id: A0A109RGQ1
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

128944:AWM75 RS06505
gene id: 128944:AWM75_RS06505
uniprot id: A0A109RH60
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

128944:AWM75 RS04615
gene id: 128944:AWM75_RS04615
uniprot id: A0A109RHS3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

128944:AWM75 RS03630
gene id: 128944:AWM75_RS03630
uniprot id: A0A0X8FKT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

128944:AWM75 RS02210
gene id: 128944:AWM75_RS02210
uniprot id: A0A109RHH7
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

128944:AWM75 RS05810
gene id: 128944:AWM75_RS05810
uniprot id: A0A0X8FLJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

128944:AWM75 RS04270
gene id: 128944:AWM75_RS04270
uniprot id: A0A120IAV3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

128944:AWM75 RS03635
gene id: 128944:AWM75_RS03635
uniprot id: A0A0X8FKU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

128944:AWM75 RS06435
gene id: 128944:AWM75_RS06435
uniprot id: A0A109RH35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HPr family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
messages: P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity.

128944:AWM75 RS05800
gene id: 128944:AWM75_RS05800
uniprot id: A0A0X8FLJ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

128944:AWM75 RS05125
gene id: 128944:AWM75_RS05125
uniprot id: A0A109RGS4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

128944:AWM75 RS05910
gene id: 128944:AWM75_RS05910
uniprot id: A0A0X8FM12
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

128944:AWM75 RS05150
gene id: 128944:AWM75_RS05150
uniprot id: A0A0X8FLA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

128944:AWM75 RS01505
gene id: 128944:AWM75_RS01505
uniprot id: A0A109RGN2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

128944:AWM75 RS01250
gene id: 128944:AWM75_RS01250
uniprot id: A0A0X8FJY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

128944:AWM75 RS02510
gene id: 128944:AWM75_RS02510
uniprot id: A0A120IAS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

128944:AWM75 RS04920
gene id: 128944:AWM75_RS04920
uniprot id: A0A0X8FLD8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

128944:AWM75 RS03640
gene id: 128944:AWM75_RS03640
uniprot id: A0A0X8FKT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

128944:AWM75 RS01720
gene id: 128944:AWM75_RS01720
uniprot id: A0A0X8FK57
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

128944:AWM75 RS07150
gene id: 128944:AWM75_RS07150
uniprot id: A0A0X8FLX8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

128944:AWM75 RS07350
gene id: 128944:AWM75_RS07350
uniprot id: A0A120IB10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

128944:AWM75 RS01235
gene id: 128944:AWM75_RS01235
uniprot id: A0A0X8FK01
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

128944:AWM75 RS01575
gene id: 128944:AWM75_RS01575
uniprot id: A0A0X8FK24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

128944:AWM75 RS04035
gene id: 128944:AWM75_RS04035
uniprot id: A0A0X8FKY0
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

128944:AWM75 RS03715
gene id: 128944:AWM75_RS03715
uniprot id: A0A0X8FKV2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

128944:AWM75 RS04925
gene id: 128944:AWM75_RS04925
uniprot id: A0A0X8FL78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

128944:AWM75 RS01740
gene id: 128944:AWM75_RS01740
uniprot id: A0A0X8FK39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

128944:AWM75 RS02120
gene id: 128944:AWM75_RS02120
uniprot id: A0A109RGB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

128944:AWM75 RS06610
gene id: 128944:AWM75_RS06610
uniprot id: A0A0X8FLY9
names: Similarity
messages: Belongs to the TelA family.

128944:AWM75 RS06205
gene id: 128944:AWM75_RS06205
uniprot id: A0A0X8FLT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

128944:AWM75 RS03525
gene id: 128944:AWM75_RS03525
uniprot id: A0A120IAT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

128944:AWM75 RS07755
gene id: 128944:AWM75_RS07755
uniprot id: A0A109RI34
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

128944:AWM75 RS07305
gene id: 128944:AWM75_RS07305
uniprot id: A0A0X8FM16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

128944:AWM75 RS01860
gene id: 128944:AWM75_RS01860
uniprot id: A0A120IAQ2
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

128944:AWM75 RS03735
gene id: 128944:AWM75_RS03735
uniprot id: A0A0X8FLA4
names: Subcellular Location Annotation
messages: Membrane

128944:AWM75 RS05390
gene id: 128944:AWM75_RS05390
uniprot id: A0A0X8FLK2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

128944:AWM75 RS00255
gene id: 128944:AWM75_RS00255
uniprot id: A0A109RHF9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

128944:AWM75 RS02200
gene id: 128944:AWM75_RS02200
uniprot id: A0A109RGH2
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

128944:AWM75 RS07370
gene id: 128944:AWM75_RS07370
uniprot id: A0A0X8FM68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

128944:AWM75 RS00015
gene id: 128944:AWM75_RS00015
uniprot id: A0A109RH90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

128944:AWM75 RS05025
gene id: 128944:AWM75_RS05025
uniprot id: A0A0X8FL87
names: Subcellular Location Annotation
messages: Membrane

128944:AWM75 RS02170
gene id: 128944:AWM75_RS02170
uniprot id: A0A0X8FKQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

128944:AWM75 RS08320
gene id: 128944:AWM75_RS08320
uniprot id: A0A0X8FMD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

128944:AWM75 RS08375
gene id: 128944:AWM75_RS08375
uniprot id: A0A109RGX2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

128944:AWM75 RS05750
gene id: 128944:AWM75_RS05750
uniprot id: A0A0X8FLK3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

128944:AWM75 RS00990
gene id: 128944:AWM75_RS00990
uniprot id: A0A0X8FJW5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

128944:AWM75 RS00275
gene id: 128944:AWM75_RS00275
uniprot id: A0A0X8FJL5
names: Similarity
messages: Belongs to the Fur family.

128944:AWM75 RS06165
gene id: 128944:AWM75_RS06165
uniprot id: A0A0X8FM37
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

128944:AWM75 RS01875
gene id: 128944:AWM75_RS01875
uniprot id: A0A109RG98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

128944:AWM75 RS01195
gene id: 128944:AWM75_RS01195
uniprot id: A0A0X8FL96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

128944:AWM75 RS04840
gene id: 128944:AWM75_RS04840
uniprot id: A0A0X8FL84
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

128944:AWM75 RS01140
gene id: 128944:AWM75_RS01140
uniprot id: A0A0X8FK17
names: Subcellular Location Annotation
messages: Membrane

128944:AWM75 RS04130
gene id: 128944:AWM75_RS04130
uniprot id: A0A0X8FMG2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

128944:AWM75 RS01545
gene id: 128944:AWM75_RS01545
uniprot id: A0A0X8FK81
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

128944:AWM75 RS00555
gene id: 128944:AWM75_RS00555
uniprot id: A0A120IAM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

128944:AWM75 RS02285
gene id: 128944:AWM75_RS02285
uniprot id: A0A120IAR5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

128944:AWM75 RS05095
gene id: 128944:AWM75_RS05095
uniprot id: A0A0X8FLA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

128944:AWM75 RS02730
gene id: 128944:AWM75_RS02730
uniprot id: A0A0X8FLS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

128944:AWM75 RS06525
gene id: 128944:AWM75_RS06525
uniprot id: A0A120IB03
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

128944:AWM75 RS06515
gene id: 128944:AWM75_RS06515
uniprot id: A0A120IAZ7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

128944:AWM75 RS04070
gene id: 128944:AWM75_RS04070
uniprot id: A0A109RGN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

128944:AWM75 RS03330
gene id: 128944:AWM75_RS03330
uniprot id: A0A0X8FKP2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

128944:AWM75 RS06275
gene id: 128944:AWM75_RS06275
uniprot id: A0A120IAZ6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

128944:AWM75 RS04815
gene id: 128944:AWM75_RS04815
uniprot id: A0A109RGJ3
names: Cofactor
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Binds 1 Mg(2+) ion per subunit.

128944:AWM75 RS02070
gene id: 128944:AWM75_RS02070
uniprot id: A0A0X8FK95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

128944:AWM75 RS02675
gene id: 128944:AWM75_RS02675
uniprot id: A0A0X8FKL7
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

128944:AWM75 RS08245
gene id: 128944:AWM75_RS08245
uniprot id: A0A0X8FME8
names: Similarity
messages: Belongs to the ArsC family.

128944:AWM75 RS04765
gene id: 128944:AWM75_RS04765
uniprot id: A0A120IAW2
names: Similarity
messages: Belongs to the peptidase S11 family.

128944:AWM75 RS03050
gene id: 128944:AWM75_RS03050
uniprot id: A0A120IAS4
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

128944:AWM75 RS01890
gene id: 128944:AWM75_RS01890
uniprot id: A0A0X8FK61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

128944:AWM75 RS04515
gene id: 128944:AWM75_RS04515
uniprot id: A0A109RGI6
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

128944:AWM75 RS02515
gene id: 128944:AWM75_RS02515
uniprot id: A0A120IAR9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

128944:AWM75 RS00320
gene id: 128944:AWM75_RS00320
uniprot id: A0A0X8FKY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

128944:AWM75 RS03670
gene id: 128944:AWM75_RS03670
uniprot id: A0A109RGX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

128944:AWM75 RS07545
gene id: 128944:AWM75_RS07545
uniprot id: A0A0X8FM30
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

128944:AWM75 RS01935
gene id: 128944:AWM75_RS01935
uniprot id: A0A0X8FLH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

128944:AWM75 RS01500
gene id: 128944:AWM75_RS01500
uniprot id: A0A0X8FK23
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

128944:AWM75 RS04050
gene id: 128944:AWM75_RS04050
uniprot id: A0A0X8FLE3
names: Similarity
messages: Belongs to the LOG family.

128944:AWM75 RS07195
gene id: 128944:AWM75_RS07195
uniprot id: A0A109RGS1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

128944:AWM75 RS04980
gene id: 128944:AWM75_RS04980
uniprot id: A0A120IAW6
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.

128944:AWM75 RS04625
gene id: 128944:AWM75_RS04625
uniprot id: A0A0X8FL48
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

128944:AWM75 RS00825
gene id: 128944:AWM75_RS00825
uniprot id: A0A0X8FJU7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

128944:AWM75 RS02595
gene id: 128944:AWM75_RS02595
uniprot id: A0A109RGC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

128944:AWM75 RS02495
gene id: 128944:AWM75_RS02495
uniprot id: A0A0X8FLP6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

128944:AWM75 RS04155
gene id: 128944:AWM75_RS04155
uniprot id: A0A120IAV4
names: Similarity
messages: Belongs to the CtsR family.

128944:AWM75 RS03045
gene id: 128944:AWM75_RS03045
uniprot id: A0A0X8FLW2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

128944:AWM75 RS03295
gene id: 128944:AWM75_RS03295
uniprot id: A0A109RGN0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

128944:AWM75 RS02810
gene id: 128944:AWM75_RS02810
uniprot id: A0A0X8FLT6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

128944:AWM75 RS04045
gene id: 128944:AWM75_RS04045
uniprot id: A0A0X8FKX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

128944:AWM75 RS04075
gene id: 128944:AWM75_RS04075
uniprot id: A0A109RGU2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

128944:AWM75 RS08675
gene id: 128944:AWM75_RS08675
uniprot id: A0A0X8FJG7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. PhnX family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Involved in phosphonate degradation.

128944:AWM75 RS02670
gene id: 128944:AWM75_RS02670
uniprot id: A0A109RHK0
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

128944:AWM75 RS06565
gene id: 128944:AWM75_RS06565
uniprot id: A0A0X8FLR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

128944:AWM75 RS02075
gene id: 128944:AWM75_RS02075
uniprot id: A0A0X8FK80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

128944:AWM75 RS08240
gene id: 128944:AWM75_RS08240
uniprot id: A0A0X8FNU0
names: Subcellular Location Annotation
messages: Membrane

128944:AWM75 RS05265
gene id: 128944:AWM75_RS05265
uniprot id: A0A0X8FLB9
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

128944:AWM75 RS04465
gene id: 128944:AWM75_RS04465
uniprot id: A0A0X8FL44
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

128944:AWM75 RS08505
gene id: 128944:AWM75_RS08505
uniprot id: A0A0X8FMW2
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

128944:AWM75 RS07820
gene id: 128944:AWM75_RS07820
uniprot id: A0A0X8FMB1
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

128944:AWM75 RS02395
gene id: 128944:AWM75_RS02395
uniprot id: A0A0X8FKD2
names: Subcellular Location Annotation
messages: Cytoplasm

128944:AWM75 RS02225
gene id: 128944:AWM75_RS02225
uniprot id: A0A0X8FKB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

128944:AWM75 RS05640
gene id: 128944:AWM75_RS05640
uniprot id: A0A0X8FLI5
names: Similarity
messages: Belongs to the peptidase C40 family.

128944:AWM75 RS05615
gene id: 128944:AWM75_RS05615
uniprot id: A0A109RH06
names: Subcellular Location Annotation
messages: Membrane

128944:AWM75 RS00480
gene id: 128944:AWM75_RS00480
uniprot id: A0A109RG48
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

128944:AWM75 RS03795
gene id: 128944:AWM75_RS03795
uniprot id: A0A0X8FKU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UPF0213 family.
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

128944:AWM75 RS05930
gene id: 128944:AWM75_RS05930
uniprot id: A0A120IAY7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

128944:AWM75 RS06495
gene id: 128944:AWM75_RS06495
uniprot id: A0A0X8FM81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

128944:AWM75 RS02785
gene id: 128944:AWM75_RS02785
uniprot id: A0A0X8FKG8
names: Subcellular Location Annotation
messages: Membrane

128944:AWM75 RS04595
gene id: 128944:AWM75_RS04595
uniprot id: A0A109RGQ6
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

128944:AWM75 RS04105
gene id: 128944:AWM75_RS04105
uniprot id: A0A0X8FL01
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.

128944:AWM75 RS04375
gene id: 128944:AWM75_RS04375
uniprot id: A0A0X8FMB1
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

128944:AWM75 RS02260
gene id: 128944:AWM75_RS02260
uniprot id: A0A109RGR0
names: Function
messages: Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions.

128944:AWM75 RS05895
gene id: 128944:AWM75_RS05895
uniprot id: A0A0X8FLK6
names: Similarity
messages: Belongs to the peptidase M29 family.

128944:AWM75 RS02600
gene id: 128944:AWM75_RS02600
uniprot id: A0A0X8FKK7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

128944:AWM75 RS01910
gene id: 128944:AWM75_RS01910
uniprot id: A0A0X8FK70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

128944:AWM75 RS05340
gene id: 128944:AWM75_RS05340
uniprot id: A0A0X8FLD4
names: Similarity
messages: Belongs to the glycosyl hydrolase 73 family.

128944:AWM75 RS04220
gene id: 128944:AWM75_RS04220
uniprot id: A0A0X8FL08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

128944:AWM75 RS07375
gene id: 128944:AWM75_RS07375
uniprot id: A0A0X8FM11
names: Similarity
messages: Belongs to the ABC transporter superfamily.

128944:AWM75 RS06430
gene id: 128944:AWM75_RS06430
uniprot id: A0A0X8FMJ6
names: Similarity
messages: Belongs to the ClpA/ClpB family.

128944:AWM75 RS02100
gene id: 128944:AWM75_RS02100
uniprot id: A0A0X8FLJ7
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

128944:AWM75 RS04685
gene id: 128944:AWM75_RS04685
uniprot id: A0A120IAW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

128944:AWM75 RS04030
gene id: 128944:AWM75_RS04030
uniprot id: A0A0X8FKZ4
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

128944:AWM75 RS02800
gene id: 128944:AWM75_RS02800
uniprot id: A0A0X8FKI7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

128944:AWM75 RS03890
gene id: 128944:AWM75_RS03890
uniprot id: A0A0X8FKW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

128944:AWM75 RS05625
gene id: 128944:AWM75_RS05625
uniprot id: A0A109RHW1
names: Subunit
messages: Monomer.

128944:AWM75 RS07615
gene id: 128944:AWM75_RS07615
uniprot id: A0A0X8FM60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

128944:AWM75 RS04835
gene id: 128944:AWM75_RS04835
uniprot id: A0A0X8FL68
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

128944:AWM75 RS02105
gene id: 128944:AWM75_RS02105
uniprot id: A0A120IAQ7
names: Similarity
messages: Belongs to the TlyA family.

128944:AWM75 RS06320
gene id: 128944:AWM75_RS06320
uniprot id: A0A0X8FLR4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

128944:AWM75 RS06895
gene id: 128944:AWM75_RS06895
uniprot id: A0A109RGZ3
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

128944:AWM75 RS01215
gene id: 128944:AWM75_RS01215
uniprot id: A0A109RHD8
names: Similarity
messages: Belongs to the peptidase S41A family.

128944:AWM75 RS00230
gene id: 128944:AWM75_RS00230
uniprot id: A0A109RGG5
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

128944:AWM75 RS05975
gene id: 128944:AWM75_RS05975
uniprot id: A0A0X8FLL0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

128944:AWM75 RS02750
gene id: 128944:AWM75_RS02750
uniprot id: A0A120IAS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

128944:AWM75 RS03700
gene id: 128944:AWM75_RS03700
uniprot id: A0A0X8FL00
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

128944:AWM75 RS01210
gene id: 128944:AWM75_RS01210
uniprot id: A0A109RHJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

128944:AWM75 RS07450
gene id: 128944:AWM75_RS07450
uniprot id: A0A0X8FM21
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

128944:AWM75 RS04460
gene id: 128944:AWM75_RS04460
uniprot id: A0A0X8FL43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

128944:AWM75 RS00340
gene id: 128944:AWM75_RS00340
uniprot id: A0A120IAM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

128944:AWM75 RS03620
gene id: 128944:AWM75_RS03620
uniprot id: A0A0X8FKZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

128944:AWM75 RS03895
gene id: 128944:AWM75_RS03895
uniprot id: A0A0X8FKW3
names: Similarity
messages: Belongs to the DEAD box helicase family.

128944:AWM75 RS01615
gene id: 128944:AWM75_RS01615
uniprot id: A0A109RG92
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

128944:AWM75 RS02160
gene id: 128944:AWM75_RS02160
uniprot id: A0A0X8FKA5
names: Function
messages: Required for transformation and DNA binding.

128944:AWM75 RS06460
gene id: 128944:AWM75_RS06460
uniprot id: A0A0X8FLS1
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

128944:AWM75 RS04745
gene id: 128944:AWM75_RS04745
uniprot id: A0A0X8FLM1
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

128944:AWM75 RS00335
gene id: 128944:AWM75_RS00335
uniprot id: A0A120IAM5
names: Similarity
messages: Belongs to the RecJ family.

128944:AWM75 RS03765
gene id: 128944:AWM75_RS03765
uniprot id: A0A109RGF4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

128944:AWM75 RS00510
gene id: 128944:AWM75_RS00510
uniprot id: A0A0X8FJP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell membrane

128944:AWM75 RS07610
gene id: 128944:AWM75_RS07610
uniprot id: A0A0X8FM39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

128944:AWM75 RS03585
gene id: 128944:AWM75_RS03585
uniprot id: A0A0X8FKT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

128944:AWM75 RS04255
gene id: 128944:AWM75_RS04255
uniprot id: A0A0X8FL17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

128944:AWM75 RS05355
gene id: 128944:AWM75_RS05355
uniprot id: A0A0X8FLE9
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

128944:AWM75 RS04085
gene id: 128944:AWM75_RS04085
uniprot id: A0A109RHW2
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

128944:AWM75 RS04265
gene id: 128944:AWM75_RS04265
uniprot id: A0A0X8FMA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

128944:AWM75 RS08110
gene id: 128944:AWM75_RS08110
uniprot id: A0A0X8FMD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

128944:AWM75 RS04630
gene id: 128944:AWM75_RS04630
uniprot id: A0A0X8FL64
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

128944:AWM75 RS03695
gene id: 128944:AWM75_RS03695
uniprot id: A0A120IAU4
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

128944:AWM75 RS07090
gene id: 128944:AWM75_RS07090
uniprot id: A0A0X8FN66
names: Function
messages: Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase.

128944:AWM75 RS02550
gene id: 128944:AWM75_RS02550
uniprot id: A0A0X8FKD8
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

128944:AWM75 RS07155
gene id: 128944:AWM75_RS07155
uniprot id: A0A0X8FLY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

128944:AWM75 RS03610
gene id: 128944:AWM75_RS03610
uniprot id: A0A109RHU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

128944:AWM75 RS05005
gene id: 128944:AWM75_RS05005
uniprot id: A0A0X8FLA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

128944:AWM75 RS06845
gene id: 128944:AWM75_RS06845
uniprot id: A0A0X8FLW6
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
messages: Homodimer.

128944:AWM75 RS03230
gene id: 128944:AWM75_RS03230
uniprot id: A0A0X8FKN2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

128944:AWM75 RS05305
gene id: 128944:AWM75_RS05305
uniprot id: A0A109RGQ2
names: Subcellular Location Annotation
messages: Membrane

128944:AWM75 RS04985
gene id: 128944:AWM75_RS04985
uniprot id: A0A120IAX5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

128944:AWM75 RS06530
gene id: 128944:AWM75_RS06530
uniprot id: A0A120IB00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

128944:AWM75 RS07430
gene id: 128944:AWM75_RS07430
uniprot id: A0A109RH38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

128944:AWM75 RS06780
gene id: 128944:AWM75_RS06780
uniprot id: A0A0X8FLW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpB family.
messages: Cytoplasm
messages: Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

128944:AWM75 RS01270
gene id: 128944:AWM75_RS01270
uniprot id: A0A0X8FLA6
names: Similarity
messages: Belongs to the thioredoxin family.

128944:AWM75 RS06455
gene id: 128944:AWM75_RS06455
uniprot id: A0A0X8FLR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Cytoplasm

128944:AWM75 RS07415
gene id: 128944:AWM75_RS07415
uniprot id: A0A109RH51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

128944:AWM75 RS01840
gene id: 128944:AWM75_RS01840
uniprot id: A0A0X8FK62
names: Subcellular Location Annotation
messages: Cell membrane

128944:AWM75 RS02905
gene id: 128944:AWM75_RS02905
uniprot id: A0A109RGP4
names: Similarity
messages: Belongs to the UPF0223 family.

128944:AWM75 RS08190
gene id: 128944:AWM75_RS08190
uniprot id: A0A0X8FMF0
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

128944:AWM75 RS04215
gene id: 128944:AWM75_RS04215
uniprot id: A0A0X8FL02
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

128944:AWM75 RS06540
gene id: 128944:AWM75_RS06540
uniprot id: A0A0X8FLS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family.
messages: Cell membrane
messages: Membrane

128944:AWM75 RS03950
gene id: 128944:AWM75_RS03950
uniprot id: A0A0X8FKX5
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

128944:AWM75 RS07140
gene id: 128944:AWM75_RS07140
uniprot id: A0A0X8FLZ4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

128944:AWM75 RS04855
gene id: 128944:AWM75_RS04855
uniprot id: A0A0X8FL76
names: Similarity
messages: Belongs to the asp23 family.

128944:AWM75 RS01525
gene id: 128944:AWM75_RS01525
uniprot id: A0A120IAQ0
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

128944:AWM75 RS05325
gene id: 128944:AWM75_RS05325
uniprot id: A0A0X8FLE1
names: Subcellular Location Annotation
messages: Membrane

128944:AWM75 RS05255
gene id: 128944:AWM75_RS05255
uniprot id: A0A0X8FLC0
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

128944:AWM75 RS02445
gene id: 128944:AWM75_RS02445
uniprot id: A0A0X8FKJ2
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

128944:AWM75 RS01150
gene id: 128944:AWM75_RS01150
uniprot id: A0A0X8FJX4
names: Similarity
messages: Belongs to the BMP lipoprotein family.

128944:AWM75 RS07165
gene id: 128944:AWM75_RS07165
uniprot id: A0A0X8FME4
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

128944:AWM75 RS03885
gene id: 128944:AWM75_RS03885
uniprot id: A0A0X8FKV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0316 family.
messages: Cell membrane
messages: Membrane

128944:AWM75 RS02585
gene id: 128944:AWM75_RS02585
uniprot id: A0A109RGK7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

128944:AWM75 RS03690
gene id: 128944:AWM75_RS03690
uniprot id: A0A120IAV0
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

128944:AWM75 RS02945
gene id: 128944:AWM75_RS02945
uniprot id: A0A0X8FKK1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

128944:AWM75 RS02990
gene id: 128944:AWM75_RS02990
uniprot id: A0A0X8FMB1
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

128944:AWM75 RS00265
gene id: 128944:AWM75_RS00265
uniprot id: A0A0X8FJS9
names: Subcellular Location Annotation
messages: Membrane

128944:AWM75 RS01685
gene id: 128944:AWM75_RS01685
uniprot id: A0A0X8FLF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

128944:AWM75 RS05680
gene id: 128944:AWM75_RS05680
uniprot id: A0A0X8FMS1
names: Subcellular Location Annotation
messages: Cell membrane

128944:AWM75 RS00880
gene id: 128944:AWM75_RS00880
uniprot id: A0A109RGD9
names: Similarity
messages: Belongs to the LOR family.

128944:AWM75 RS07220
gene id: 128944:AWM75_RS07220
uniprot id: A0A0X8FM02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

128944:AWM75 RS07265
gene id: 128944:AWM75_RS07265
uniprot id: A0A109RH02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

128944:AWM75 RS05985
gene id: 128944:AWM75_RS05985
uniprot id: A0A0X8FM27
names: Similarity
messages: Belongs to the Fur family.

128944:AWM75 RS04120
gene id: 128944:AWM75_RS04120
uniprot id: A0A0X8FKZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

128944:AWM75 RS07445
gene id: 128944:AWM75_RS07445
uniprot id: A0A0X8FM78
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecU family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation.

128944:AWM75 RS00835
gene id: 128944:AWM75_RS00835
uniprot id: A0A0X8FJU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LPG synthase family.
messages: Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
messages: Cell membrane
messages: Membrane

128944:AWM75 RS00475
gene id: 128944:AWM75_RS00475
uniprot id: A0A0X8FKZ9
names: Subcellular Location Annotation
messages: Membrane

128944:AWM75 RS08440
gene id: 128944:AWM75_RS08440
uniprot id: A0A0X8FNP0
names: Subcellular Location Annotation
messages: Membrane

128944:AWM75 RS02365
gene id: 128944:AWM75_RS02365
uniprot id: A0A109RGB8
names: Subcellular Location Annotation
messages: Membrane

128944:AWM75 RS06195
gene id: 128944:AWM75_RS06195
uniprot id: A0A109RI40
names: Similarity
messages: Belongs to the UDPGP type 2 family.

128944:AWM75 RS01870
gene id: 128944:AWM75_RS01870
uniprot id: A0A109RGA1
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

128944:AWM75 RS03550
gene id: 128944:AWM75_RS03550
uniprot id: A0A0X8FKR9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

128944:AWM75 RS05925
gene id: 128944:AWM75_RS05925
uniprot id: A0A0X8FMU1
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

128944:AWM75 RS03360
gene id: 128944:AWM75_RS03360
uniprot id: A0A0X8FM00
names: Subcellular Location Annotation
messages: Membrane

128944:AWM75 RS00560
gene id: 128944:AWM75_RS00560
uniprot id: A0A120IAM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

128944:AWM75 RS01895
gene id: 128944:AWM75_RS01895
uniprot id: A0A0X8FK74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

128944:AWM75 RS03545
gene id: 128944:AWM75_RS03545
uniprot id: A0A0X8FKY3
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

128944:AWM75 RS05315
gene id: 128944:AWM75_RS05315
uniprot id: A0A0X8FLC8
names: Similarity
messages: Belongs to the leucine-binding protein family.

128944:AWM75 RS03775
gene id: 128944:AWM75_RS03775
uniprot id: A0A0X8FL09
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

128944:AWM75 RS03595
gene id: 128944:AWM75_RS03595
uniprot id: A0A0X8FM29
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

128944:AWM75 RS07525
gene id: 128944:AWM75_RS07525
uniprot id: A0A0X8FM31
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

128944:AWM75 RS04555
gene id: 128944:AWM75_RS04555
uniprot id: A0A0X8FL45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

128944:AWM75 RS07645
gene id: 128944:AWM75_RS07645
uniprot id: A0A0X8FM73
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

128944:AWM75 RS02920
gene id: 128944:AWM75_RS02920
uniprot id: A0A0X8FKQ1
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

128944:AWM75 RS05100
gene id: 128944:AWM75_RS05100
uniprot id: A0A0X8FL98
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

128944:AWM75 RS03625
gene id: 128944:AWM75_RS03625
uniprot id: A0A0X8FKS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

128944:AWM75 RS07290
gene id: 128944:AWM75_RS07290
uniprot id: A0A0X8FM55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

128944:AWM75 RS02815
gene id: 128944:AWM75_RS02815
uniprot id: A0A0X8FMB1
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

128944:AWM75 RS01245
gene id: 128944:AWM75_RS01245
uniprot id: A0A0X8FJZ4
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

128944:AWM75 RS01970
gene id: 128944:AWM75_RS01970
uniprot id: A0A0X8FK87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

128944:AWM75 RS05590
gene id: 128944:AWM75_RS05590
uniprot id: A0A0X8FLX0
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

128944:AWM75 RS00660
gene id: 128944:AWM75_RS00660
uniprot id: A0A0X8FJW3
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

128944:AWM75 RS07215
gene id: 128944:AWM75_RS07215
uniprot id: A0A0X8FM05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

128944:AWM75 RS03500
gene id: 128944:AWM75_RS03500
uniprot id: A0A0X8FKR4
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

128944:AWM75 RS07470
gene id: 128944:AWM75_RS07470
uniprot id: A0A0X8FM18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

128944:AWM75 RS08070
gene id: 128944:AWM75_RS08070
uniprot id: A0A0X8FMF1
names: Subcellular Location Annotation
messages: Membrane

128944:AWM75 RS03860
gene id: 128944:AWM75_RS03860
uniprot id: A0A109RHQ1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

128944:AWM75 RS06545
gene id: 128944:AWM75_RS06545
uniprot id: A0A0X8FLT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

128944:AWM75 RS05515
gene id: 128944:AWM75_RS05515
uniprot id: A0A0X8FLH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

128944:AWM75 RS02005
gene id: 128944:AWM75_RS02005
uniprot id: A0A0X8FKN6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

128944:AWM75 RS03430
gene id: 128944:AWM75_RS03430
uniprot id: A0A0X8FKR5
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

128944:AWM75 RS07920
gene id: 128944:AWM75_RS07920
uniprot id: A0A0X8FM96
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.

128944:AWM75 RS08260
gene id: 128944:AWM75_RS08260
uniprot id: A0A0X8FMD2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

128944:AWM75 RS08075
gene id: 128944:AWM75_RS08075
uniprot id: A0A0X8FM98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

128944:AWM75 RS08250
gene id: 128944:AWM75_RS08250
uniprot id: A0A0X8FMB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Ycf16 family.
messages: Membrane

128944:AWM75 RS00525
gene id: 128944:AWM75_RS00525
uniprot id: A0A0X8FJR5
names: Subcellular Location Annotation
messages: Membrane

128944:AWM75 RS06875
gene id: 128944:AWM75_RS06875
uniprot id: A0A0X8FMC3
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

128944:AWM75 RS03615
gene id: 128944:AWM75_RS03615
uniprot id: A0A109RHP3
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

128944:AWM75 RS01695
gene id: 128944:AWM75_RS01695
uniprot id: A0A109RGF6
names: Similarity
messages: Belongs to the FBPase class 3 family.

128944:AWM75 RS05065
gene id: 128944:AWM75_RS05065
uniprot id: A0A109RGP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

128944:AWM75 RS07110
gene id: 128944:AWM75_RS07110
uniprot id: A0A120IB13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

128944:AWM75 RS07455
gene id: 128944:AWM75_RS07455
uniprot id: A0A0X8FM35
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

128944:AWM75 RS00440
gene id: 128944:AWM75_RS00440
uniprot id: A0A0X8FJM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diaminopimelate dehydrogenase family.
messages: Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.
messages: Homodimer.

128944:AWM75 RS01775
gene id: 128944:AWM75_RS01775
uniprot id: A0A120IAQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

128944:AWM75 RS04300
gene id: 128944:AWM75_RS04300
uniprot id: A0A0X8FL23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

128944:AWM75 RS03685
gene id: 128944:AWM75_RS03685
uniprot id: A0A120IAU1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

128944:AWM75 RS02775
gene id: 128944:AWM75_RS02775
uniprot id: A0A0X8FKH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

128944:AWM75 RS01945
gene id: 128944:AWM75_RS01945
uniprot id: A0A109RGG2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

128944:AWM75 RS05245
gene id: 128944:AWM75_RS05245
uniprot id: A0A0X8FMI4
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

128944:AWM75 RS06720
gene id: 128944:AWM75_RS06720
uniprot id: A0A0X8FLU2
names: Caution
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

128944:AWM75 RS02140
gene id: 128944:AWM75_RS02140
uniprot id: A0A0X8FK88
names: Similarity
messages: Belongs to the peptidase M24B family.

128944:AWM75 RS03820
gene id: 128944:AWM75_RS03820
uniprot id: A0A109RH01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease N1/T1 family.
messages: Secreted

128944:AWM75 RS02925
gene id: 128944:AWM75_RS02925
uniprot id: A0A0X8FKI5
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

128944:AWM75 RS05085
gene id: 128944:AWM75_RS05085
uniprot id: A0A0X8FLB2
names: Similarity
messages: Belongs to the DDAH family.

128944:AWM75 RS06410
gene id: 128944:AWM75_RS06410
uniprot id: A0A0X8FLS4
names: Similarity
messages: Belongs to the thioester dehydratase family. FabZ subfamily.

128944:AWM75 RS00035
gene id: 128944:AWM75_RS00035
uniprot id: A0A0X8FJL1
names: Subcellular Location Annotation
messages: Membrane

128944:AWM75 RS03495
gene id: 128944:AWM75_RS03495
uniprot id: A0A0X8FKR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

128944:AWM75 RS08290
gene id: 128944:AWM75_RS08290
uniprot id: A0A120IB28
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

128944:AWM75 RS04455
gene id: 128944:AWM75_RS04455
uniprot id: A0A0X8FL27
names: Similarity
messages: Belongs to the peptidase M16 family.

128944:AWM75 RS07250
gene id: 128944:AWM75_RS07250
uniprot id: A0A109RHF1
names: Function
names: Similarity
names: Subunit
messages: A non-essential component of RNA polymerase (RNAP).
messages: Belongs to the RNA polymerase subunit epsilon family.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunit. The core is associated with a delta subunit, and at least one of epsilon or omega. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

128944:AWM75 RS07720
gene id: 128944:AWM75_RS07720
uniprot id: A0A0X8FM82
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

128944:AWM75 RS05840
gene id: 128944:AWM75_RS05840
uniprot id: A0A109RGU6
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

128944:AWM75 RS00775
gene id: 128944:AWM75_RS00775
uniprot id: A0A0X8FJS3
names: Subcellular Location Annotation
messages: cell wall

128944:AWM75 RS05240
gene id: 128944:AWM75_RS05240
uniprot id: A0A0X8FLD3
names: Similarity
messages: Belongs to the UDPGP type 2 family.

128944:AWM75 RS06370
gene id: 128944:AWM75_RS06370
uniprot id: A0A0X8FLR5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

128944:AWM75 RS03370
gene id: 128944:AWM75_RS03370
uniprot id: A0A109RGR3
names: Subcellular Location Annotation
messages: Membrane

128944:AWM75 RS01420
gene id: 128944:AWM75_RS01420
uniprot id: A0A0X8FK13
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

128944:AWM75 RS00435
gene id: 128944:AWM75_RS00435
uniprot id: A0A0X8FJQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

128944:AWM75 RS04475
gene id: 128944:AWM75_RS04475
uniprot id: A0A0X8FL35
names: Subcellular Location Annotation
messages: Membrane

128944:AWM75 RS01200
gene id: 128944:AWM75_RS01200
uniprot id: A0A109RGB4
names: Similarity
messages: Belongs to the DprA/Smf family.

128944:AWM75 RS00145
gene id: 128944:AWM75_RS00145
uniprot id: A0A0X8FJI3
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

128944:AWM75 RS04670
gene id: 128944:AWM75_RS04670
uniprot id: A0A109RH11
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

128944:AWM75 RS02015
gene id: 128944:AWM75_RS02015
uniprot id: A0A109RGP9
names: Similarity
messages: Belongs to the RNase H family.

128944:AWM75 RS04770
gene id: 128944:AWM75_RS04770
uniprot id: A0A109RGT9
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

128944:AWM75 RS03905
gene id: 128944:AWM75_RS03905
uniprot id: A0A0X8FKX6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

128944:AWM75 RS05935
gene id: 128944:AWM75_RS05935
uniprot id: A0A120IAY6
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

128944:AWM75 RS00845
gene id: 128944:AWM75_RS00845
uniprot id: A0A0X8FJS7
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

128944:AWM75 RS04320
gene id: 128944:AWM75_RS04320
uniprot id: A0A0X8FL15
names: Similarity
messages: Belongs to the disproportionating enzyme family.

128944:AWM75 RS07460
gene id: 128944:AWM75_RS07460
uniprot id: A0A0X8FM34
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

128944:AWM75 RS02735
gene id: 128944:AWM75_RS02735
uniprot id: A0A120IAS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

128944:AWM75 RS04715
gene id: 128944:AWM75_RS04715
uniprot id: A0A0X8FL61
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

128944:AWM75 RS02455
gene id: 128944:AWM75_RS02455
uniprot id: A0A0X8FKE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

128944:AWM75 RS02530
gene id: 128944:AWM75_RS02530
uniprot id: A0A0X8FKF2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

128944:AWM75 RS01750
gene id: 128944:AWM75_RS01750
uniprot id: A0A0X8FK54
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

128944:AWM75 RS03010
gene id: 128944:AWM75_RS03010
uniprot id: A0A0X8FKK5
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

128944:AWM75 RS04880
gene id: 128944:AWM75_RS04880
uniprot id: A0A109RH65
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

128944:AWM75 RS00855
gene id: 128944:AWM75_RS00855
uniprot id: A0A0X8FJT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

128944:AWM75 RS07295
gene id: 128944:AWM75_RS07295
uniprot id: A0A0X8FM01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

128944:AWM75 RS03015
gene id: 128944:AWM75_RS03015
uniprot id: A0A0X8FKK2
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.

128944:AWM75 RS04100
gene id: 128944:AWM75_RS04100
uniprot id: A0A0X8FKZ3
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

128944:AWM75 RS07640
gene id: 128944:AWM75_RS07640
uniprot id: A0A0X8FMK8
names: Similarity
messages: Belongs to the UPF0177 family.

128944:AWM75 RS02910
gene id: 128944:AWM75_RS02910
uniprot id: A0A109RHR3
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

128944:AWM75 RS03085
gene id: 128944:AWM75_RS03085
uniprot id: A0A0X8FKL5
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

128944:AWM75 RS02540
gene id: 128944:AWM75_RS02540
uniprot id: A0A0X8FKE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

128944:AWM75 RS05180
gene id: 128944:AWM75_RS05180
uniprot id: A0A0X8FLS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

128944:AWM75 RS01960
gene id: 128944:AWM75_RS01960
uniprot id: A0A0X8FKD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

128944:AWM75 RS01940
gene id: 128944:AWM75_RS01940
uniprot id: A0A109RGG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

128944:AWM75 RS02050
gene id: 128944:AWM75_RS02050
uniprot id: A0A0X8FK79
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

128944:AWM75 RS05070
gene id: 128944:AWM75_RS05070
uniprot id: A0A0X8FLG1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

128944:AWM75 RS03600
gene id: 128944:AWM75_RS03600
uniprot id: A0A109RGM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

128944:AWM75 RS00310
gene id: 128944:AWM75_RS00310
uniprot id: A0A0X8FJK0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

128944:AWM75 RS05525
gene id: 128944:AWM75_RS05525
uniprot id: A0A0X8FMQ1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

128944:AWM75 RS08225
gene id: 128944:AWM75_RS08225
uniprot id: A0A0X8FMH2
names: Subcellular Location Annotation
messages: Membrane

128944:AWM75 RS07210
gene id: 128944:AWM75_RS07210
uniprot id: A0A0X8FLZ2
names: Similarity
messages: Belongs to the UPF0473 family.

128944:AWM75 RS01825
gene id: 128944:AWM75_RS01825
uniprot id: A0A0X8FK59
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

128944:AWM75 RS01600
gene id: 128944:AWM75_RS01600
uniprot id: A0A0X8FLE2
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

128944:AWM75 RS03020
gene id: 128944:AWM75_RS03020
uniprot id: A0A0X8FKL2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

128944:AWM75 RS00935
gene id: 128944:AWM75_RS00935
uniprot id: A0A0X8FJT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

128944:AWM75 RS01670
gene id: 128944:AWM75_RS01670
uniprot id: A0A0X8FKK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

128944:AWM75 RS02575
gene id: 128944:AWM75_RS02575
uniprot id: A0A0X8FLQ7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

128944:AWM75 RS07175
gene id: 128944:AWM75_RS07175
uniprot id: A0A109RH46
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

128944:AWM75 RS03675
gene id: 128944:AWM75_RS03675
uniprot id: A0A0X8FM41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

128944:AWM75 RS05020
gene id: 128944:AWM75_RS05020
uniprot id: A0A0X8FL95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

128944:AWM75 RS02840
gene id: 128944:AWM75_RS02840
uniprot id: A0A0X8FKH7
names: Subcellular Location Annotation
messages: Membrane

128944:AWM75 RS07300
gene id: 128944:AWM75_RS07300
uniprot id: A0A0X8FM15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: chloroplast

128944:AWM75 RS02295
gene id: 128944:AWM75_RS02295
uniprot id: A0A0X8FKH2
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

128944:AWM75 RS06760
gene id: 128944:AWM75_RS06760
uniprot id: A0A120IB05
names: Similarity
messages: Belongs to the Fur family.

128944:AWM75 RS04865
gene id: 128944:AWM75_RS04865
uniprot id: A0A0X8FLN1
names: Similarity
messages: Belongs to the asp23 family.

128944:AWM75 RS06775
gene id: 128944:AWM75_RS06775
uniprot id: A0A0X8FLW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

128944:AWM75 RS03270
gene id: 128944:AWM75_RS03270
uniprot id: A0A0X8FKP7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

128944:AWM75 RS03285
gene id: 128944:AWM75_RS03285
uniprot id: A0A120IAT2
names: Function
names: Similarity
messages: Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.

128944:AWM75 RS08105
gene id: 128944:AWM75_RS08105
uniprot id: A0A0X8FMR6
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

128944:AWM75 RS04710
gene id: 128944:AWM75_RS04710
uniprot id: A0A0X8FLB7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

128944:AWM75 RS01855
gene id: 128944:AWM75_RS01855
uniprot id: A0A0X8FLG7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

128944:AWM75 RS01495
gene id: 128944:AWM75_RS01495
uniprot id: A0A0X8FKI4
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

128944:AWM75 RS07690
gene id: 128944:AWM75_RS07690
uniprot id: A0A0X8FM70
names: Similarity
messages: Belongs to the YjdM family.

128944:AWM75 RS04600
gene id: 128944:AWM75_RS04600
uniprot id: A0A0X8FNS7
names: Similarity
messages: Belongs to the XFP family.

128944:AWM75 RS07480
gene id: 128944:AWM75_RS07480
uniprot id: A0A0X8FMI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

128944:AWM75 RS03025
gene id: 128944:AWM75_RS03025
uniprot id: A0A0X8FKK3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

128944:AWM75 RS05410
gene id: 128944:AWM75_RS05410
uniprot id: A0A0X8FLE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

128944:AWM75 RS00290
gene id: 128944:AWM75_RS00290
uniprot id: A0A0X8FJL9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

128944:AWM75 RS00305
gene id: 128944:AWM75_RS00305
uniprot id: A0A0X8FK08
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

128944:AWM75 RS03665
gene id: 128944:AWM75_RS03665
uniprot id: A0A0X8FKU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

128944:AWM75 RS05740
gene id: 128944:AWM75_RS05740
uniprot id: A0A0X8FMJ3
names: Similarity
messages: Belongs to the glutamine synthetase family.

128944:AWM75 RS06790
gene id: 128944:AWM75_RS06790
uniprot id: A0A0X8FLU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

128944:AWM75 RS06655
gene id: 128944:AWM75_RS06655
uniprot id: A0A109RHD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

128944:AWM75 RS02650
gene id: 128944:AWM75_RS02650
uniprot id: A0A0X8FLR7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

128944:AWM75 RS05260
gene id: 128944:AWM75_RS05260
uniprot id: A0A0X8FLC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

128944:AWM75 RS03515
gene id: 128944:AWM75_RS03515
uniprot id: A0A109RGR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

128944:AWM75 RS01020
gene id: 128944:AWM75_RS01020
uniprot id: A0A0X8FKB3
names: Subcellular Location Annotation
messages: Membrane

128944:AWM75 RS01175
gene id: 128944:AWM75_RS01175
uniprot id: A0A0X8FJX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase family. ParE type 2 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

128944:AWM75 RS03580
gene id: 128944:AWM75_RS03580
uniprot id: A0A0X8FL85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

128944:AWM75 RS04260
gene id: 128944:AWM75_RS04260
uniprot id: A0A109RGU4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

128944:AWM75 RS01570
gene id: 128944:AWM75_RS01570
uniprot id: A0A0X8FK31
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

128944:AWM75 RS05155
gene id: 128944:AWM75_RS05155
uniprot id: A0A0X8FLC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

128944:AWM75 RS02190
gene id: 128944:AWM75_RS02190
uniprot id: A0A0X8FLK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

128944:AWM75 RS07420
gene id: 128944:AWM75_RS07420
uniprot id: A0A0X8FNA6
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

128944:AWM75 RS07680
gene id: 128944:AWM75_RS07680
uniprot id: A0A0X8FMB1
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

128944:AWM75 RS02740
gene id: 128944:AWM75_RS02740
uniprot id: A0A120IAS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

128944:AWM75 RS06240
gene id: 128944:AWM75_RS06240
uniprot id: A0A0X8FM50
names: Similarity
messages: Belongs to the asp23 family.

128944:AWM75 RS03460
gene id: 128944:AWM75_RS03460
uniprot id: A0A120IAT9
names: Similarity
messages: Belongs to the RutC family.

128944:AWM75 RS05200
gene id: 128944:AWM75_RS05200
uniprot id: A0A120IAX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

128944:AWM75 RS00715
gene id: 128944:AWM75_RS00715
uniprot id: A0A0X8FMB1
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

128944:AWM75 RS07925
gene id: 128944:AWM75_RS07925
uniprot id: A0A0X8FMA0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

128944:AWM75 RS04660
gene id: 128944:AWM75_RS04660
uniprot id: A0A0X8FLL4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

128944:AWM75 RS08180
gene id: 128944:AWM75_RS08180
uniprot id: A0A0X8FMB0
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

128944:AWM75 RS00595
gene id: 128944:AWM75_RS00595
uniprot id: A0A0X8FJQ4
names: Similarity
messages: Belongs to the creatininase superfamily.

128944:AWM75 RS05835
gene id: 128944:AWM75_RS05835
uniprot id: A0A0X8FMT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

128944:AWM75 RS05570
gene id: 128944:AWM75_RS05570
uniprot id: A0A0X8FLG8
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

128944:AWM75 RS03650
gene id: 128944:AWM75_RS03650
uniprot id: A0A0X8FKT4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

128944:AWM75 RS07705
gene id: 128944:AWM75_RS07705
uniprot id: A0A0X8FM49
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

128944:AWM75 RS00220
gene id: 128944:AWM75_RS00220
uniprot id: A0A0X8FK00
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates ribosomal protein L11.

128944:AWM75 RS08115
gene id: 128944:AWM75_RS08115
uniprot id: A0A109RH71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

128944:AWM75 RS01760
gene id: 128944:AWM75_RS01760
uniprot id: A0A0X8FLF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

128944:AWM75 RS06555
gene id: 128944:AWM75_RS06555
uniprot id: A0A0X8FLS6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

128944:AWM75 RS04250
gene id: 128944:AWM75_RS04250
uniprot id: A0A0X8FLG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

128944:AWM75 RS06265
gene id: 128944:AWM75_RS06265
uniprot id: A0A120IAZ0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

128944:AWM75 RS02275
gene id: 128944:AWM75_RS02275
uniprot id: A0A120IAR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

128944:AWM75 RS04720
gene id: 128944:AWM75_RS04720
uniprot id: A0A0X8FL74
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

128944:AWM75 RS03505
gene id: 128944:AWM75_RS03505
uniprot id: A0A0X8FL77
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

128944:AWM75 RS05490
gene id: 128944:AWM75_RS05490
uniprot id: A0A0X8FLF5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

128944:AWM75 RS06755
gene id: 128944:AWM75_RS06755
uniprot id: A0A120IB08
names: Similarity
messages: Belongs to the CvfB family.

128944:AWM75 RS03035
gene id: 128944:AWM75_RS03035
uniprot id: A0A0X8FKL6
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

128944:AWM75 RS00155
gene id: 128944:AWM75_RS00155
uniprot id: A0A0X8FKW2
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

128944:AWM75 RS06595
gene id: 128944:AWM75_RS06595
uniprot id: A0A109RH08
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

128944:AWM75 RS07900
gene id: 128944:AWM75_RS07900
uniprot id: A0A109RGV4
names: Subcellular Location Annotation
messages: Membrane

128944:AWM75 RS04530
gene id: 128944:AWM75_RS04530
uniprot id: A0A0X8FL37
names: Subcellular Location Annotation
messages: Membrane

128944:AWM75 RS03540
gene id: 128944:AWM75_RS03540
uniprot id: A0A109RGJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

128944:AWM75 RS01820
gene id: 128944:AWM75_RS01820
uniprot id: A0A0X8FK55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

128944:AWM75 RS01725
gene id: 128944:AWM75_RS01725
uniprot id: A0A0X8FK58
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

128944:AWM75 RS04095
gene id: 128944:AWM75_RS04095
uniprot id: A0A0X8FL49
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

128944:AWM75 RS06535
gene id: 128944:AWM75_RS06535
uniprot id: A0A0X8FLX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsL family.
messages: Cell membrane
messages: Essential cell division protein.
messages: Membrane

128944:AWM75 RS00865
gene id: 128944:AWM75_RS00865
uniprot id: A0A0X8FL47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

128944:AWM75 RS06135
gene id: 128944:AWM75_RS06135
uniprot id: A0A0X8FLL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PrsA family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.

128944:AWM75 RS02110
gene id: 128944:AWM75_RS02110
uniprot id: A0A109RGJ0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

128944:AWM75 RS04635
gene id: 128944:AWM75_RS04635
uniprot id: A0A0X8FL62
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

128944:AWM75 RS07540
gene id: 128944:AWM75_RS07540
uniprot id: A0A0X8FM32
names: Similarity
messages: Belongs to the PrpD family.

128944:AWM75 RS06840
gene id: 128944:AWM75_RS06840
uniprot id: A0A0X8FM17
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

128944:AWM75 RS07225
gene id: 128944:AWM75_RS07225
uniprot id: A0A0X8FLZ3
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

128944:AWM75 RS00100
gene id: 128944:AWM75_RS00100
uniprot id: A0A120IAL8
names: Similarity
names: Subunit
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
messages: Homotetramer.

128944:AWM75 RS01105
gene id: 128944:AWM75_RS01105
uniprot id: A0A109RGH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

128944:AWM75 RS06570
gene id: 128944:AWM75_RS06570
uniprot id: A0A0X8FM92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

128944:AWM75 RS02960
gene id: 128944:AWM75_RS02960
uniprot id: A0A0X8FKK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

128944:AWM75 RS05765
gene id: 128944:AWM75_RS05765
uniprot id: A0A120IAY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

128944:AWM75 RS02565
gene id: 128944:AWM75_RS02565
uniprot id: A0A0X8FKF5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

128944:AWM75 RS04390
gene id: 128944:AWM75_RS04390
uniprot id: A0A0X8FL34
names: Similarity
messages: Belongs to the peptidase M20A family.

128944:AWM75 RS04890
gene id: 128944:AWM75_RS04890
uniprot id: A0A109RGR5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

128944:AWM75 RS07665
gene id: 128944:AWM75_RS07665
uniprot id: A0A109RH43
names: Subcellular Location Annotation
messages: Membrane

128944:AWM75 RS02150
gene id: 128944:AWM75_RS02150
uniprot id: A0A0X8FKA2
names: Function
messages: Required for transformation and DNA binding.

128944:AWM75 RS05185
gene id: 128944:AWM75_RS05185
uniprot id: A0A0X8FLC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

128944:AWM75 RS06270
gene id: 128944:AWM75_RS06270
uniprot id: A0A120IAZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

128944:AWM75 RS05090
gene id: 128944:AWM75_RS05090
uniprot id: A0A0X8FLA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

128944:AWM75 RS04410
gene id: 128944:AWM75_RS04410
uniprot id: A0A0X8FLI4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

128944:AWM75 RS03865
gene id: 128944:AWM75_RS03865
uniprot id: A0A0X8FL19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

128944:AWM75 RS00150
gene id: 128944:AWM75_RS00150
uniprot id: A0A109RGB0
names: Similarity
messages: Belongs to the thioester dehydratase family. FabZ subfamily.

128944:AWM75 RS06745
gene id: 128944:AWM75_RS06745
uniprot id: A0A120IB02
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

128944:AWM75 RS03855
gene id: 128944:AWM75_RS03855
uniprot id: A0A109RHV1
names: Similarity
messages: Belongs to the thioester dehydratase family. FabZ subfamily.

128944:AWM75 RS03570
gene id: 128944:AWM75_RS03570
uniprot id: A0A0X8FKS7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

128944:AWM75 RS01885
gene id: 128944:AWM75_RS01885
uniprot id: A0A0X8FMJ9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

128944:AWM75 RS05945
gene id: 128944:AWM75_RS05945
uniprot id: A0A120IAZ1
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

128944:AWM75 RS02425
gene id: 128944:AWM75_RS02425
uniprot id: A0A109RGI1
names: Subcellular Location Annotation
messages: Membrane

128944:AWM75 RS05915
gene id: 128944:AWM75_RS05915
uniprot id: A0A0X8FLM4
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

128944:AWM75 RS03530
gene id: 128944:AWM75_RS03530
uniprot id: A0A109RGN8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

128944:AWM75 RS00875
gene id: 128944:AWM75_RS00875
uniprot id: A0A120IAN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines hypoxanthine and guanine to form the corresponding ribonucleotides IMP (inosine 5'-monophosphate) and GMP (guanosine 5'-monophosphate), with the release of PPi.

128944:AWM75 RS05595
gene id: 128944:AWM75_RS05595
uniprot id: A0A0X8FLI3
names: Similarity
messages: Belongs to the UPF0045 family.

128944:AWM75 RS05825
gene id: 128944:AWM75_RS05825
uniprot id: A0A0X8FLL3
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

128944:AWM75 RS07200
gene id: 128944:AWM75_RS07200
uniprot id: A0A109RGX1
names: Similarity
messages: Belongs to the UPF0297 family.

128944:AWM75 RS01665
gene id: 128944:AWM75_RS01665
uniprot id: A0A0X8FK30
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

128944:AWM75 RS06405
gene id: 128944:AWM75_RS06405
uniprot id: A0A0X8FM71
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

128944:AWM75 RS05770
gene id: 128944:AWM75_RS05770
uniprot id: A0A109RGY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

128944:AWM75 RS06230
gene id: 128944:AWM75_RS06230
uniprot id: A0A0X8FLN0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

128944:AWM75 RS01755
gene id: 128944:AWM75_RS01755
uniprot id: A0A109RGP0
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

128944:AWM75 RS00120
gene id: 128944:AWM75_RS00120
uniprot id: A0A0X8FJL8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

128944:AWM75 RS00900
gene id: 128944:AWM75_RS00900
uniprot id: A0A0X8FJU1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

128944:AWM75 RS07500
gene id: 128944:AWM75_RS07500
uniprot id: A0A109RH13
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

128944:AWM75 RS03935
gene id: 128944:AWM75_RS03935
uniprot id: A0A120IAU8
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

128944:AWM75 RS01395
gene id: 128944:AWM75_RS01395
uniprot id: A0A0X8FK05
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

128944:AWM75 RS07170
gene id: 128944:AWM75_RS07170
uniprot id: A0A0X8FM08
names: Function
names: Similarity
names: Subunit
messages: In the N-terminal section; belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily.
messages: Monomer.
messages: Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine.

128944:AWM75 RS03930
gene id: 128944:AWM75_RS03930
uniprot id: A0A120IAV5
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

128944:AWM75 RS08175
gene id: 128944:AWM75_RS08175
uniprot id: A0A0X8FMA5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

128944:AWM75 RS07320
gene id: 128944:AWM75_RS07320
uniprot id: A0A0X8FM04
names: Similarity
messages: Belongs to the RutC family.

128944:AWM75 RS05695
gene id: 128944:AWM75_RS05695
uniprot id: A0A120IAY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

128944:AWM75 RS01170
gene id: 128944:AWM75_RS01170
uniprot id: A0A0X8FJY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

128944:AWM75 RS01025
gene id: 128944:AWM75_RS01025
uniprot id: A0A0X8FJU9
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

128944:AWM75 RS03780
gene id: 128944:AWM75_RS03780
uniprot id: A0A0X8FKV1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

128944:AWM75 RS06575
gene id: 128944:AWM75_RS06575
uniprot id: A0A0X8FLU6
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

128944:AWM75 RS02975
gene id: 128944:AWM75_RS02975
uniprot id: A0A120IAT3
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

128944:AWM75 RS02935
gene id: 128944:AWM75_RS02935
uniprot id: A0A0X8FKJ6
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

128944:AWM75 RS06815
gene id: 128944:AWM75_RS06815
uniprot id: A0A0X8FN49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

128944:AWM75 RS03485
gene id: 128944:AWM75_RS03485
uniprot id: A0A0X8FKR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

128944:AWM75 RS02330
gene id: 128944:AWM75_RS02330
uniprot id: A0A0X8FKS6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

128944:AWM75 RS06300
gene id: 128944:AWM75_RS06300
uniprot id: A0A0X8FLP7
names: Similarity
messages: Belongs to the asp23 family.

128944:AWM75 RS01185
gene id: 128944:AWM75_RS01185
uniprot id: A0A0X8FJX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor.

128944:AWM75 RS06665
gene id: 128944:AWM75_RS06665
uniprot id: A0A109RGY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

128944:AWM75 RS01470
gene id: 128944:AWM75_RS01470
uniprot id: A0A0X8FK29
names: Function
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the irreversible reduction of 2,3-butanediol to (S)-acetoin in the presence of NADH.

128944:AWM75 RS08120
gene id: 128944:AWM75_RS08120
uniprot id: A0A0X8FNJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

128944:AWM75 RS06335
gene id: 128944:AWM75_RS06335
uniprot id: A0A120IAZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

128944:AWM75 RS01290
gene id: 128944:AWM75_RS01290
uniprot id: A0A120IAP5
names: Subcellular Location Annotation
messages: Cytoplasm

128944:AWM75 RS03560
gene id: 128944:AWM75_RS03560
uniprot id: A0A0X8FKT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

128944:AWM75 RS01865
gene id: 128944:AWM75_RS01865
uniprot id: A0A109RGH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

128944:AWM75 RS00655
gene id: 128944:AWM75_RS00655
uniprot id: A0A109RG51
names: Similarity
messages: Belongs to the PemK/MazF family.

128944:AWM75 RS03575
gene id: 128944:AWM75_RS03575
uniprot id: A0A0X8FKS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

128944:AWM75 RS05010
gene id: 128944:AWM75_RS05010
uniprot id: A0A0X8FLA2
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

128944:AWM75 RS06090
gene id: 128944:AWM75_RS06090
uniprot id: A0A120IAY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

128944:AWM75 RS01485
gene id: 128944:AWM75_RS01485
uniprot id: A0A0X8FK22
names: Subcellular Location Annotation
messages: Membrane

128944:AWM75 RS03790
gene id: 128944:AWM75_RS03790
uniprot id: A0A0X8FKW0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

128944:AWM75 RS02475
gene id: 128944:AWM75_RS02475
uniprot id: A0A0X8FKC9
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

128944:AWM75 RS07045
gene id: 128944:AWM75_RS07045
uniprot id: A0A0X8FLX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CitD family.
messages: Covalent carrier of the coenzyme of citrate lyase.
messages: Cytoplasm
messages: Oligomer with a subunit composition of (alpha,beta,gamma)6.

128944:AWM75 RS02250
gene id: 128944:AWM75_RS02250
uniprot id: A0A0X8FKR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

128944:AWM75 RS06310
gene id: 128944:AWM75_RS06310
uniprot id: A0A0X8FLN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

128944:AWM75 RS07660
gene id: 128944:AWM75_RS07660
uniprot id: A0A120IB21
names: Subcellular Location Annotation
messages: Membrane

128944:AWM75 RS05105
gene id: 128944:AWM75_RS05105
uniprot id: A0A0X8FLR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

128944:AWM75 RS02765
gene id: 128944:AWM75_RS02765
uniprot id: A0A0X8FKH9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

128944:AWM75 RS04490
gene id: 128944:AWM75_RS04490
uniprot id: A0A0X8FL52
names: Function
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

128944:AWM75 RS07960
gene id: 128944:AWM75_RS07960
uniprot id: A0A0X8FNH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

128944:AWM75 RS02685
gene id: 128944:AWM75_RS02685
uniprot id: A0A0X8FKF6
names: Similarity
messages: Belongs to the asp23 family.

128944:AWM75 RS08185
gene id: 128944:AWM75_RS08185
uniprot id: A0A0X8FMS6
names: Similarity
messages: Belongs to the EamA transporter family.

128944:AWM75 RS01540
gene id: 128944:AWM75_RS01540
uniprot id: A0A120IAP8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

128944:AWM75 RS03945
gene id: 128944:AWM75_RS03945
uniprot id: A0A0X8FKW8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

128944:AWM75 RS01560
gene id: 128944:AWM75_RS01560
uniprot id: A0A0X8FK35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

128944:AWM75 RS00505
gene id: 128944:AWM75_RS00505
uniprot id: A0A0X8FJM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Cell membrane
messages: Membrane

128944:AWM75 RS06340
gene id: 128944:AWM75_RS06340
uniprot id: A0A109RGZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

128944:AWM75 RS07790
gene id: 128944:AWM75_RS07790
uniprot id: A0A0X8FM63
names: Subcellular Location Annotation
messages: Membrane

128944:AWM75 RS02725
gene id: 128944:AWM75_RS02725
uniprot id: A0A109RGT1
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

128944:AWM75 RS01880
gene id: 128944:AWM75_RS01880
uniprot id: A0A0X8FKC2
names: Similarity
messages: Belongs to the ribF family.

128944:AWM75 RS00545
gene id: 128944:AWM75_RS00545
uniprot id: A0A109RGK1
names: Similarity
messages: Belongs to the KdgT transporter family.

128944:AWM75 RS03490
gene id: 128944:AWM75_RS03490
uniprot id: A0A0X8FMJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

128944:AWM75 RS00380
gene id: 128944:AWM75_RS00380
uniprot id: A0A0X8FK19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.

128944:AWM75 RS05960
gene id: 128944:AWM75_RS05960
uniprot id: A0A0X8FLM3
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

128944:AWM75 RS01715
gene id: 128944:AWM75_RS01715
uniprot id: A0A0X8FK43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

128944:AWM75 RS01070
gene id: 128944:AWM75_RS01070
uniprot id: A0A0X8FJX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

128944:AWM75 RS04115
gene id: 128944:AWM75_RS04115
uniprot id: A0A0X8FKY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane

128944:AWM75 RS08390
gene id: 128944:AWM75_RS08390
uniprot id: A0A0X8FME3
names: Similarity
messages: Belongs to the UPF0145 family.

128944:AWM75 RS04560
gene id: 128944:AWM75_RS04560
uniprot id: A0A0X8FL38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

128944:AWM75 RS00225
gene id: 128944:AWM75_RS00225
uniprot id: A0A0X8FJJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

128944:AWM75 RS02280
gene id: 128944:AWM75_RS02280
uniprot id: A0A120IAR3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

128944:AWM75 RS00315
gene id: 128944:AWM75_RS00315
uniprot id: A0A109RGJ2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

128944:AWM75 RS02420
gene id: 128944:AWM75_RS02420
uniprot id: A0A0X8FLN6
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

128944:AWM75 RS04315
gene id: 128944:AWM75_RS04315
uniprot id: A0A0X8FL07
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

128944:AWM75 RS08200
gene id: 128944:AWM75_RS08200
uniprot id: A0A0X8FNL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

128944:AWM75 RS06830
gene id: 128944:AWM75_RS06830
uniprot id: A0A109RGQ9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

128944:AWM75 RS01605
gene id: 128944:AWM75_RS01605
uniprot id: A0A120IAP7
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

128944:AWM75 RS04575
gene id: 128944:AWM75_RS04575
uniprot id: A0A0X8FL63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

128944:AWM75 RS01450
gene id: 128944:AWM75_RS01450
uniprot id: A0A109RHE7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

128944:AWM75 RS00260
gene id: 128944:AWM75_RS00260
uniprot id: A0A109RH99
names: Similarity
messages: Belongs to the peptidase S49 family.

128944:AWM75 RS08100
gene id: 128944:AWM75_RS08100
uniprot id: A0A0X8FMA2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

128944:AWM75 RS03815
gene id: 128944:AWM75_RS03815
uniprot id: A0A0X8FKW6
names: Similarity
messages: Belongs to the barstar family.

128944:AWM75 RS05350
gene id: 128944:AWM75_RS05350
uniprot id: A0A0X8FLU0
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

128944:AWM75 RS01160
gene id: 128944:AWM75_RS01160
uniprot id: A0A0X8FJY5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

128944:AWM75 RS00630
gene id: 128944:AWM75_RS00630
uniprot id: A0A109RGD0
names: Similarity
messages: Belongs to the CapA family.

128944:AWM75 RS02885
gene id: 128944:AWM75_RS02885
uniprot id: A0A0X8FKJ7
names: Subcellular Location Annotation
messages: Membrane

128944:AWM75 RS02215
gene id: 128944:AWM75_RS02215
uniprot id: A0A0X8FKG2
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

128944:AWM75 RS03900
gene id: 128944:AWM75_RS03900
uniprot id: A0A0X8FLC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

128944:AWM75 RS04970
gene id: 128944:AWM75_RS04970
uniprot id: A0A0X8FMI0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

128944:AWM75 RS08095
gene id: 128944:AWM75_RS08095
uniprot id: A0A0X8FM95
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

128944:AWM75 RS05520
gene id: 128944:AWM75_RS05520
uniprot id: A0A109RGZ2
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

128944:AWM75 RS02135
gene id: 128944:AWM75_RS02135
uniprot id: A0A0X8FKF3
names: Similarity
messages: Belongs to the asp23 family.

128944:AWM75 RS03350
gene id: 128944:AWM75_RS03350
uniprot id: A0A0X8FKQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

128944:AWM75 RS01610
gene id: 128944:AWM75_RS01610
uniprot id: A0A109RGG8
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

128944:AWM75 RS02095
gene id: 128944:AWM75_RS02095
uniprot id: A0A109RGL3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

128944:AWM75 RS02220
gene id: 128944:AWM75_RS02220
uniprot id: A0A0X8FK98
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

128944:AWM75 RS01800
gene id: 128944:AWM75_RS01800
uniprot id: A0A0X8FMB1
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

128944:AWM75 RS03380
gene id: 128944:AWM75_RS03380
uniprot id: A0A109RHT1
names: Function
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the irreversible reduction of 2,3-butanediol to (S)-acetoin in the presence of NADH.

128944:AWM75 RS05685
gene id: 128944:AWM75_RS05685
uniprot id: A0A120IAY2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

128944:AWM75 RS08365
gene id: 128944:AWM75_RS08365
uniprot id: A0A120IB35
names: Subcellular Location Annotation
messages: Membrane

128944:AWM75 RS02720
gene id: 128944:AWM75_RS02720
uniprot id: A0A0X8FKH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

128944:AWM75 RS07650
gene id: 128944:AWM75_RS07650
uniprot id: A0A109RH56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

128944:AWM75 RS07070
gene id: 128944:AWM75_RS07070
uniprot id: A0A0X8FLX2
names: Subcellular Location Annotation
messages: Membrane

128944:AWM75 RS04645
gene id: 128944:AWM75_RS04645
uniprot id: A0A0X8FL50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

128944:AWM75 RS02640
gene id: 128944:AWM75_RS02640
uniprot id: A0A0X8FKG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

128944:AWM75 RS03095
gene id: 128944:AWM75_RS03095
uniprot id: A0A0X8FKL8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

128944:AWM75 RS02535
gene id: 128944:AWM75_RS02535
uniprot id: A0A0X8FKF0
names: Subcellular Location Annotation
messages: Membrane

128944:AWM75 RS04690
gene id: 128944:AWM75_RS04690
uniprot id: A0A120IAX0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

128944:AWM75 RS05920
gene id: 128944:AWM75_RS05920
uniprot id: A0A109RH50
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

128944:AWM75 RS01555
gene id: 128944:AWM75_RS01555
uniprot id: A0A0X8FK38
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.