1288484:G6R31 RS07230
gene id: 1288484:G6R31_RS07230
uniprot id: A0A6G7H3V7
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1288484:G6R31 RS11810
gene id: 1288484:G6R31_RS11810
uniprot id: A0A6G7H5P3
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1288484:G6R31 RS08945
gene id: 1288484:G6R31_RS08945
uniprot id: A0A6G7H544
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1288484:G6R31 RS00705
gene id: 1288484:G6R31_RS00705
uniprot id: A0A6G7H0E0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1288484:G6R31 RS13720
gene id: 1288484:G6R31_RS13720
uniprot id: A0A6G7H6L6
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1288484:G6R31 RS00340
gene id: 1288484:G6R31_RS00340
uniprot id: A0A6G7H0V2
names: Similarity
messages: Belongs to the peptidase M29 family.

1288484:G6R31 RS04595
gene id: 1288484:G6R31_RS04595
uniprot id: A0A6G7H3C1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1288484:G6R31 RS01050
gene id: 1288484:G6R31_RS01050
uniprot id: A0A6G7H199
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1288484:G6R31 RS11475
gene id: 1288484:G6R31_RS11475
uniprot id: A0A6G7H656
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1288484:G6R31 RS01875
gene id: 1288484:G6R31_RS01875
uniprot id: A0A6G7H1N9
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1288484:G6R31 RS10765
gene id: 1288484:G6R31_RS10765
uniprot id: A0A6G7H5T5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1288484:G6R31 RS05825
gene id: 1288484:G6R31_RS05825
uniprot id: A0A6G7H3L6
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1288484:G6R31 RS02350
gene id: 1288484:G6R31_RS02350
uniprot id: A0A6G7H1P0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1288484:G6R31 RS07330
gene id: 1288484:G6R31_RS07330
uniprot id: A0A6G7H4D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1288484:G6R31 RS09090
gene id: 1288484:G6R31_RS09090
uniprot id: A0A6G7H4F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1288484:G6R31 RS09785
gene id: 1288484:G6R31_RS09785
uniprot id: A0A6G7H5I0
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1288484:G6R31 RS11445
gene id: 1288484:G6R31_RS11445
uniprot id: A0A6G7H7X3
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

1288484:G6R31 RS03155
gene id: 1288484:G6R31_RS03155
uniprot id: A0A6G7H1H1
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1288484:G6R31 RS14755
gene id: 1288484:G6R31_RS14755
uniprot id: A0A6G7H8R2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1288484:G6R31 RS06180
gene id: 1288484:G6R31_RS06180
uniprot id: A0A6G7H304
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1288484:G6R31 RS08735
gene id: 1288484:G6R31_RS08735
uniprot id: A0A6G7H5D4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1288484:G6R31 RS07160
gene id: 1288484:G6R31_RS07160
uniprot id: A0A6G7H3G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1288484:G6R31 RS08100
gene id: 1288484:G6R31_RS08100
uniprot id: A0A6G7H411
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the transfer of the amino group of L-glutamate to [LysW]-aminoadipate 6-semialdehyde, generating [LysW]-gamma-L-lysine.
messages: Cytoplasm
messages: Homodimer.

1288484:G6R31 RS03030
gene id: 1288484:G6R31_RS03030
uniprot id: A0A6G7H1E2
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1288484:G6R31 RS15300
gene id: 1288484:G6R31_RS15300
uniprot id: A0A6G7H8D9
names: Similarity
messages: Belongs to the sulfate adenylyltransferase family.

1288484:G6R31 RS15290
gene id: 1288484:G6R31_RS15290
uniprot id: A0A6G7H921
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

1288484:G6R31 RS07145
gene id: 1288484:G6R31_RS07145
uniprot id: A0A6G7H3K6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

1288484:G6R31 RS00910
gene id: 1288484:G6R31_RS00910
uniprot id: A0A6G7H0D2
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1288484:G6R31 RS06115
gene id: 1288484:G6R31_RS06115
uniprot id: A0A6G7H2Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1288484:G6R31 RS14240
gene id: 1288484:G6R31_RS14240
uniprot id: A0A6G7H8A5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1288484:G6R31 RS11825
gene id: 1288484:G6R31_RS11825
uniprot id: A0A6G7H6F3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1288484:G6R31 RS10045
gene id: 1288484:G6R31_RS10045
uniprot id: A0A6G7H4W7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1288484:G6R31 RS06260
gene id: 1288484:G6R31_RS06260
uniprot id: A0A6G7H310
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1288484:G6R31 RS09305
gene id: 1288484:G6R31_RS09305
uniprot id: A0A6G7H5A3
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

1288484:G6R31 RS06865
gene id: 1288484:G6R31_RS06865
uniprot id: A0A6G7H400
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1288484:G6R31 RS00070
gene id: 1288484:G6R31_RS00070
uniprot id: A0A6G7H000
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1288484:G6R31 RS02730
gene id: 1288484:G6R31_RS02730
uniprot id: A0A6G7H190
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1288484:G6R31 RS12345
gene id: 1288484:G6R31_RS12345
uniprot id: A0A6G7H6Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1288484:G6R31 RS04695
gene id: 1288484:G6R31_RS04695
uniprot id: A0A6G7H2D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1288484:G6R31 RS07195
gene id: 1288484:G6R31_RS07195
uniprot id: A0A6G7H430
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1288484:G6R31 RS04500
gene id: 1288484:G6R31_RS04500
uniprot id: A0A6G7H263
names: Function
names: Similarity
messages: Belongs to the NanE family.
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

1288484:G6R31 RS00540
gene id: 1288484:G6R31_RS00540
uniprot id: A0A6G7H0T5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1288484:G6R31 RS14015
gene id: 1288484:G6R31_RS14015
uniprot id: A0A6G7H864
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

1288484:G6R31 RS02790
gene id: 1288484:G6R31_RS02790
uniprot id: A0A6G7H1Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1288484:G6R31 RS01745
gene id: 1288484:G6R31_RS01745
uniprot id: A0A6G7H1V8
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1288484:G6R31 RS03150
gene id: 1288484:G6R31_RS03150
uniprot id: A0A6G7H2L3
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS02625
gene id: 1288484:G6R31_RS02625
uniprot id: A0A6G7H1J3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1288484:G6R31 RS10380
gene id: 1288484:G6R31_RS10380
uniprot id: A0A6G7H5S8
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS11290
gene id: 1288484:G6R31_RS11290
uniprot id: A0A6G7H625
names: Similarity
messages: Belongs to the DinB family.

1288484:G6R31 RS00595
gene id: 1288484:G6R31_RS00595
uniprot id: A0A6G7H0B9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1288484:G6R31 RS12260
gene id: 1288484:G6R31_RS12260
uniprot id: A0A6G7H711
names: Similarity
messages: Belongs to the RutC family.

1288484:G6R31 RS09440
gene id: 1288484:G6R31_RS09440
uniprot id: A0A6G7H4M1
names: Similarity
messages: Belongs to the GSP E family.

1288484:G6R31 RS01995
gene id: 1288484:G6R31_RS01995
uniprot id: A0A6G7H1R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1288484:G6R31 RS14655
gene id: 1288484:G6R31_RS14655
uniprot id: A0A6G7H8I2
names: Function
messages: Long-chain fatty alcohol oxidase involved in the omega-oxidation pathway of lipid degradation.

1288484:G6R31 RS14570
gene id: 1288484:G6R31_RS14570
uniprot id: A0A6G7H8K5
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1288484:G6R31 RS01305
gene id: 1288484:G6R31_RS01305
uniprot id: A0A6G7H1B2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1288484:G6R31 RS09745
gene id: 1288484:G6R31_RS09745
uniprot id: A0A6G7H4T9
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1288484:G6R31 RS00155
gene id: 1288484:G6R31_RS00155
uniprot id: A0A6G7H007
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1288484:G6R31 RS00525
gene id: 1288484:G6R31_RS00525
uniprot id: A0A6G7H0I3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1288484:G6R31 RS05720
gene id: 1288484:G6R31_RS05720
uniprot id: A0A6G7H3J3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1288484:G6R31 RS10040
gene id: 1288484:G6R31_RS10040
uniprot id: A0A6G7H604
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1288484:G6R31 RS06950
gene id: 1288484:G6R31_RS06950
uniprot id: A0A6G7H3C9
names: Similarity
messages: Belongs to the leucine-binding protein family.

1288484:G6R31 RS02970
gene id: 1288484:G6R31_RS02970
uniprot id: A0A6G7H2I2
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1288484:G6R31 RS10115
gene id: 1288484:G6R31_RS10115
uniprot id: A0A6G7H591
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1288484:G6R31 RS03200
gene id: 1288484:G6R31_RS03200
uniprot id: A0A6G7H1H3
names: Similarity
messages: Belongs to the peptidase S41A family.

1288484:G6R31 RS02050
gene id: 1288484:G6R31_RS02050
uniprot id: A0A6G7H0X2
names: Similarity
messages: Belongs to the PGI/PMI family.

1288484:G6R31 RS06890
gene id: 1288484:G6R31_RS06890
uniprot id: A0A6G7H3C4
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1288484:G6R31 RS15225
gene id: 1288484:G6R31_RS15225
uniprot id: A0A6G7H8T2
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

1288484:G6R31 RS03415
gene id: 1288484:G6R31_RS03415
uniprot id: A0A6G7H1Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 15 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1288484:G6R31 RS06595
gene id: 1288484:G6R31_RS06595
uniprot id: A0A6G7H374
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

1288484:G6R31 RS14780
gene id: 1288484:G6R31_RS14780
uniprot id: A0A6G7H8K2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS02500
gene id: 1288484:G6R31_RS02500
uniprot id: A0A6G7H152
names: Similarity
messages: Belongs to the peptidase C40 family.

1288484:G6R31 RS09385
gene id: 1288484:G6R31_RS09385
uniprot id: A0A6G7H4L1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1288484:G6R31 RS14040
gene id: 1288484:G6R31_RS14040
uniprot id: A0A6G7H7K4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1288484:G6R31 RS10085
gene id: 1288484:G6R31_RS10085
uniprot id: A0A6G7H4Z7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1288484:G6R31 RS02240
gene id: 1288484:G6R31_RS02240
uniprot id: A0A6G7H1M0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1288484:G6R31 RS09115
gene id: 1288484:G6R31_RS09115
uniprot id: A0A6G7H574
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1288484:G6R31 RS12275
gene id: 1288484:G6R31_RS12275
uniprot id: A0A6G7H5W1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1288484:G6R31 RS10160
gene id: 1288484:G6R31_RS10160
uniprot id: A0A6G7H4Y7
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS13920
gene id: 1288484:G6R31_RS13920
uniprot id: A0A6G7H7I4
names: Caution
names: Cofactor
names: Domain
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Consists of two distinct domains; an N-terminal heme-containing oxygen-binding domain and a C-terminal reductase domain with binding sites for FAD and NAD(P)H.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS13050
gene id: 1288484:G6R31_RS13050
uniprot id: A0A6G7H6B0
names: Similarity
messages: Belongs to the universal stress protein A family.

1288484:G6R31 RS02485
gene id: 1288484:G6R31_RS02485
uniprot id: A0A6G7H188
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS04705
gene id: 1288484:G6R31_RS04705
uniprot id: A0A6G7H3E0
names: Caution
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS06110
gene id: 1288484:G6R31_RS06110
uniprot id: A0A6G7H436
names: Similarity
messages: Belongs to the peptidase C56 family.

1288484:G6R31 RS07200
gene id: 1288484:G6R31_RS07200
uniprot id: A0A6G7H3L5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1288484:G6R31 RS07905
gene id: 1288484:G6R31_RS07905
uniprot id: A0A6G7H866
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS07525
gene id: 1288484:G6R31_RS07525
uniprot id: A0A6G7H3M7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1288484:G6R31 RS06070
gene id: 1288484:G6R31_RS06070
uniprot id: A0A6G7H6Z4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Cytoplasm
messages: Homodimer.
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1288484:G6R31 RS09895
gene id: 1288484:G6R31_RS09895
uniprot id: A0A6G7H5K0
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1288484:G6R31 RS14450
gene id: 1288484:G6R31_RS14450
uniprot id: A0A6G7H7S2
names: Similarity
messages: Belongs to the arginase family.

1288484:G6R31 RS00935
gene id: 1288484:G6R31_RS00935
uniprot id: A0A6G7H105
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

1288484:G6R31 RS08540
gene id: 1288484:G6R31_RS08540
uniprot id: A0A6G7H4U8
names: Function
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1288484:G6R31 RS01945
gene id: 1288484:G6R31_RS01945
uniprot id: A0A6G7H173
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1288484:G6R31 RS07775
gene id: 1288484:G6R31_RS07775
uniprot id: A0A6G7H4J3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

1288484:G6R31 RS09190
gene id: 1288484:G6R31_RS09190
uniprot id: A0A6G7H583
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS01920
gene id: 1288484:G6R31_RS01920
uniprot id: A0A6G7H1Y9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1288484:G6R31 RS13000
gene id: 1288484:G6R31_RS13000
uniprot id: A0A6G7H7D1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1288484:G6R31 RS01415
gene id: 1288484:G6R31_RS01415
uniprot id: A0A6G7H0Y2
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1288484:G6R31 RS02885
gene id: 1288484:G6R31_RS02885
uniprot id: A0A6G7H1C0
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1288484:G6R31 RS08180
gene id: 1288484:G6R31_RS08180
uniprot id: A0A6G7H712
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

1288484:G6R31 RS11685
gene id: 1288484:G6R31_RS11685
uniprot id: A0A6G7H5M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1288484:G6R31 RS14670
gene id: 1288484:G6R31_RS14670
uniprot id: A0A6G7H8Z5
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1288484:G6R31 RS10245
gene id: 1288484:G6R31_RS10245
uniprot id: A0A6G7H5K4
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS02910
gene id: 1288484:G6R31_RS02910
uniprot id: A0A6G7H1G9
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS16725
gene id: 1288484:G6R31_RS16725
uniprot id: A0A6G7H910
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1288484:G6R31 RS06010
gene id: 1288484:G6R31_RS06010
uniprot id: A0A6G7H2X1
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Periplasm

1288484:G6R31 RS08980
gene id: 1288484:G6R31_RS08980
uniprot id: A0A6G7H572
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1288484:G6R31 RS10520
gene id: 1288484:G6R31_RS10520
uniprot id: A0A6G7H573
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1288484:G6R31 RS02125
gene id: 1288484:G6R31_RS02125
uniprot id: A0A6G7H1L7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1288484:G6R31 RS07555
gene id: 1288484:G6R31_RS07555
uniprot id: A0A6G7H3P2
names: Similarity
messages: Belongs to the type II topoisomerase GyrB family.

1288484:G6R31 RS08065
gene id: 1288484:G6R31_RS08065
uniprot id: A0A6G7H3X5
names: Similarity
messages: Belongs to the lycopene cyclase family.

1288484:G6R31 RS01635
gene id: 1288484:G6R31_RS01635
uniprot id: A0A6G7H122
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1288484:G6R31 RS03560
gene id: 1288484:G6R31_RS03560
uniprot id: A0A6G7H2I4
names: Similarity
messages: Belongs to the PspA/IM30 family.

1288484:G6R31 RS08520
gene id: 1288484:G6R31_RS08520
uniprot id: A0A6G7H454
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1288484:G6R31 RS10815
gene id: 1288484:G6R31_RS10815
uniprot id: A0A6G7H5Z9
names: Similarity
messages: Belongs to the FUN14 family.

1288484:G6R31 RS01985
gene id: 1288484:G6R31_RS01985
uniprot id: A0A6G7H7C9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1288484:G6R31 RS03460
gene id: 1288484:G6R31_RS03460
uniprot id: A0A6G7H2E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1288484:G6R31 RS07730
gene id: 1288484:G6R31_RS07730
uniprot id: A0A6G7H3S5
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1288484:G6R31 RS09395
gene id: 1288484:G6R31_RS09395
uniprot id: A0A6G7H4K4
names: Similarity
messages: Belongs to the barstar family.

1288484:G6R31 RS07455
gene id: 1288484:G6R31_RS07455
uniprot id: A0A6G7H3L8
names: Similarity
messages: Belongs to the UPF0111 family.

1288484:G6R31 RS07530
gene id: 1288484:G6R31_RS07530
uniprot id: A0A6G7H407
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1288484:G6R31 RS12450
gene id: 1288484:G6R31_RS12450
uniprot id: A0A6G7H5Z1
names: Similarity
messages: Belongs to the cytochrome P450 family.

1288484:G6R31 RS10840
gene id: 1288484:G6R31_RS10840
uniprot id: A0A6G7H598
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1288484:G6R31 RS06980
gene id: 1288484:G6R31_RS06980
uniprot id: A0A6G7H421
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1288484:G6R31 RS07655
gene id: 1288484:G6R31_RS07655
uniprot id: A0A6G7H4H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1288484:G6R31 RS06775
gene id: 1288484:G6R31_RS06775
uniprot id: A0A6G7H3A4
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS13700
gene id: 1288484:G6R31_RS13700
uniprot id: A0A6G7H7A9
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

1288484:G6R31 RS11575
gene id: 1288484:G6R31_RS11575
uniprot id: A0A6G7H7B6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1288484:G6R31 RS14380
gene id: 1288484:G6R31_RS14380
uniprot id: A0A6G7H7U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

1288484:G6R31 RS11525
gene id: 1288484:G6R31_RS11525
uniprot id: A0A6G7H5W9
names: Similarity
messages: Belongs to the ParB family.

1288484:G6R31 RS14300
gene id: 1288484:G6R31_RS14300
uniprot id: A0A6G7H8F7
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1288484:G6R31 RS09805
gene id: 1288484:G6R31_RS09805
uniprot id: A0A6G7H5W4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1288484:G6R31 RS11200
gene id: 1288484:G6R31_RS11200
uniprot id: A0A6G7H5E1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

1288484:G6R31 RS04460
gene id: 1288484:G6R31_RS04460
uniprot id: A0A6G7H7N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1288484:G6R31 RS04555
gene id: 1288484:G6R31_RS04555
uniprot id: A0A6G7H273
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS02030
gene id: 1288484:G6R31_RS02030
uniprot id: A0A6G7H106
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1288484:G6R31 RS03375
gene id: 1288484:G6R31_RS03375
uniprot id: A0A6G7H2Q3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS05470
gene id: 1288484:G6R31_RS05470
uniprot id: A0A6G7H2N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1288484:G6R31 RS02020
gene id: 1288484:G6R31_RS02020
uniprot id: A0A6G7H1N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1288484:G6R31 RS01725
gene id: 1288484:G6R31_RS01725
uniprot id: A0A6G7H1D0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1288484:G6R31 RS11025
gene id: 1288484:G6R31_RS11025
uniprot id: A0A6G7H5A7
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1288484:G6R31 RS03785
gene id: 1288484:G6R31_RS03785
uniprot id: A0A6G7H2M4
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

1288484:G6R31 RS09260
gene id: 1288484:G6R31_RS09260
uniprot id: A0A6G7H4J1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

1288484:G6R31 RS01370
gene id: 1288484:G6R31_RS01370
uniprot id: A0A6G7H0P5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

1288484:G6R31 RS13410
gene id: 1288484:G6R31_RS13410
uniprot id: A0A6G7H6G6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS14585
gene id: 1288484:G6R31_RS14585
uniprot id: A0A6G7H7Z0
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1288484:G6R31 RS11985
gene id: 1288484:G6R31_RS11985
uniprot id: A0A6G7H6H3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1288484:G6R31 RS09930
gene id: 1288484:G6R31_RS09930
uniprot id: A0A6G7H4S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

1288484:G6R31 RS02765
gene id: 1288484:G6R31_RS02765
uniprot id: A0A6G7H2E1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homodimer.

1288484:G6R31 RS12080
gene id: 1288484:G6R31_RS12080
uniprot id: A0A6G7H6Y1
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1288484:G6R31 RS06530
gene id: 1288484:G6R31_RS06530
uniprot id: A0A6G7H3R2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1288484:G6R31 RS07570
gene id: 1288484:G6R31_RS07570
uniprot id: A0A6G7H4H8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1288484:G6R31 RS09825
gene id: 1288484:G6R31_RS09825
uniprot id: A0A6G7H542
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

1288484:G6R31 RS03515
gene id: 1288484:G6R31_RS03515
uniprot id: A0A6G7H2B8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1288484:G6R31 RS03420
gene id: 1288484:G6R31_RS03420
uniprot id: A0A6G7H1L2
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1288484:G6R31 RS00475
gene id: 1288484:G6R31_RS00475
uniprot id: A0A6G7H0X1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1288484:G6R31 RS02220
gene id: 1288484:G6R31_RS02220
uniprot id: A0A6G7H100
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1288484:G6R31 RS13095
gene id: 1288484:G6R31_RS13095
uniprot id: A0A6G7H6X0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1288484:G6R31 RS00585
gene id: 1288484:G6R31_RS00585
uniprot id: A0A6G7H0Z1
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS13795
gene id: 1288484:G6R31_RS13795
uniprot id: A0A6G7H7F4
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1288484:G6R31 RS02115
gene id: 1288484:G6R31_RS02115
uniprot id: A0A6G7H7V8
names: Similarity
messages: Belongs to the RelA/SpoT family.

1288484:G6R31 RS12215
gene id: 1288484:G6R31_RS12215
uniprot id: A0A6G7H6P9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1288484:G6R31 RS02445
gene id: 1288484:G6R31_RS02445
uniprot id: A0A6G7H140
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

1288484:G6R31 RS12085
gene id: 1288484:G6R31_RS12085
uniprot id: A0A6G7H845
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1288484:G6R31 RS00520
gene id: 1288484:G6R31_RS00520
uniprot id: A0A6G7H062
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1288484:G6R31 RS10035
gene id: 1288484:G6R31_RS10035
uniprot id: A0A6G7H4X1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1288484:G6R31 RS02815
gene id: 1288484:G6R31_RS02815
uniprot id: A0A6G7H2F2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1288484:G6R31 RS08810
gene id: 1288484:G6R31_RS08810
uniprot id: A0A6G7H541
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS11605
gene id: 1288484:G6R31_RS11605
uniprot id: A0A6G7H676
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1288484:G6R31 RS06740
gene id: 1288484:G6R31_RS06740
uniprot id: A0A6G7H849
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

1288484:G6R31 RS02810
gene id: 1288484:G6R31_RS02810
uniprot id: A0A6G7H1A5
names: Similarity
messages: Belongs to the YciI family.

1288484:G6R31 RS09225
gene id: 1288484:G6R31_RS09225
uniprot id: A0A6G7H4G0
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS10100
gene id: 1288484:G6R31_RS10100
uniprot id: A0A6G7H4X7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1288484:G6R31 RS01520
gene id: 1288484:G6R31_RS01520
uniprot id: A0A6G7H1B6
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1288484:G6R31 RS09595
gene id: 1288484:G6R31_RS09595
uniprot id: A0A6G7H5F0
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS01470
gene id: 1288484:G6R31_RS01470
uniprot id: A0A6G7H1A6
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1288484:G6R31 RS16540
gene id: 1288484:G6R31_RS16540
uniprot id: A0A6G7H9I4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1288484:G6R31 RS00955
gene id: 1288484:G6R31_RS00955
uniprot id: A0A6G7H1H7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1288484:G6R31 RS07580
gene id: 1288484:G6R31_RS07580
uniprot id: A0A6G7H417
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1288484:G6R31 RS06860
gene id: 1288484:G6R31_RS06860
uniprot id: A0A6G7H3N8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1288484:G6R31 RS11020
gene id: 1288484:G6R31_RS11020
uniprot id: A0A6G7H658
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1288484:G6R31 RS00760
gene id: 1288484:G6R31_RS00760
uniprot id: A0A6G7H0F0
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1288484:G6R31 RS07275
gene id: 1288484:G6R31_RS07275
uniprot id: A0A6G7H4C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1288484:G6R31 RS01290
gene id: 1288484:G6R31_RS01290
uniprot id: A0A6G7H0J2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS09485
gene id: 1288484:G6R31_RS09485
uniprot id: A0A6G7H4P9
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS12130
gene id: 1288484:G6R31_RS12130
uniprot id: A0A6G7H5V7
names: Similarity
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.

1288484:G6R31 RS16355
gene id: 1288484:G6R31_RS16355
uniprot id: A0A6G7H9J3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1288484:G6R31 RS10845
gene id: 1288484:G6R31_RS10845
uniprot id: A0A6G7H627
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1288484:G6R31 RS15130
gene id: 1288484:G6R31_RS15130
uniprot id: A0A6G7H985
names: Similarity
messages: Belongs to the malate synthase family.

1288484:G6R31 RS07660
gene id: 1288484:G6R31_RS07660
uniprot id: A0A6G7H4B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1288484:G6R31 RS09840
gene id: 1288484:G6R31_RS09840
uniprot id: A0A6G7H5D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1288484:G6R31 RS05870
gene id: 1288484:G6R31_RS05870
uniprot id: A0A6G7H3P0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1288484:G6R31 RS04540
gene id: 1288484:G6R31_RS04540
uniprot id: A0A6G7H270
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1288484:G6R31 RS00720
gene id: 1288484:G6R31_RS00720
uniprot id: A0A6G7H0B0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1288484:G6R31 RS05675
gene id: 1288484:G6R31_RS05675
uniprot id: A0A6G7H2V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1288484:G6R31 RS15045
gene id: 1288484:G6R31_RS15045
uniprot id: A0A6G7H8C6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1288484:G6R31 RS07745
gene id: 1288484:G6R31_RS07745
uniprot id: A0A6G7H3R9
names: Similarity
messages: Belongs to the Fur family.

1288484:G6R31 RS15085
gene id: 1288484:G6R31_RS15085
uniprot id: A0A6G7H862
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1288484:G6R31 RS13560
gene id: 1288484:G6R31_RS13560
uniprot id: A0A6G7H6U5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1288484:G6R31 RS03000
gene id: 1288484:G6R31_RS03000
uniprot id: A0A6G7H228
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS13415
gene id: 1288484:G6R31_RS13415
uniprot id: A0A6G7H7K0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1288484:G6R31 RS10080
gene id: 1288484:G6R31_RS10080
uniprot id: A0A6G7H5H5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1288484:G6R31 RS11460
gene id: 1288484:G6R31_RS11460
uniprot id: A0A6G7H5V9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1288484:G6R31 RS09415
gene id: 1288484:G6R31_RS09415
uniprot id: A0A6G7H596
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS06725
gene id: 1288484:G6R31_RS06725
uniprot id: A0A6G7H4D7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1288484:G6R31 RS04585
gene id: 1288484:G6R31_RS04585
uniprot id: A0A6G7H2B4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1288484:G6R31 RS10630
gene id: 1288484:G6R31_RS10630
uniprot id: A0A6G7H5X0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1288484:G6R31 RS10675
gene id: 1288484:G6R31_RS10675
uniprot id: A0A6G7H5Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

1288484:G6R31 RS08300
gene id: 1288484:G6R31_RS08300
uniprot id: A0A6G7H4T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family. BdbC subfamily.
messages: Membrane

1288484:G6R31 RS12515
gene id: 1288484:G6R31_RS12515
uniprot id: A0A6G7H6R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1288484:G6R31 RS06365
gene id: 1288484:G6R31_RS06365
uniprot id: A0A6G7H367
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1288484:G6R31 RS00280
gene id: 1288484:G6R31_RS00280
uniprot id: A0A6G7H0U1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1288484:G6R31 RS07370
gene id: 1288484:G6R31_RS07370
uniprot id: A0A6G7H3P3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1288484:G6R31 RS16855
gene id: 1288484:G6R31_RS16855
uniprot id: A0A6G7H4A3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1288484:G6R31 RS12330
gene id: 1288484:G6R31_RS12330
uniprot id: A0A6G7H5X1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1288484:G6R31 RS10915
gene id: 1288484:G6R31_RS10915
uniprot id: A0A6G7H5L8
names: Similarity
messages: Belongs to the SufE family.

1288484:G6R31 RS00905
gene id: 1288484:G6R31_RS00905
uniprot id: A0A6G7H179
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1288484:G6R31 RS03465
gene id: 1288484:G6R31_RS03465
uniprot id: A0A6G7H291
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 15 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1288484:G6R31 RS14215
gene id: 1288484:G6R31_RS14215
uniprot id: A0A6G7H7L2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1288484:G6R31 RS03450
gene id: 1288484:G6R31_RS03450
uniprot id: A0A6G7H2A8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 15 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1288484:G6R31 RS15155
gene id: 1288484:G6R31_RS15155
uniprot id: A0A6G7H8E5
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1288484:G6R31 RS10965
gene id: 1288484:G6R31_RS10965
uniprot id: A0A6G7H597
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1288484:G6R31 RS13755
gene id: 1288484:G6R31_RS13755
uniprot id: A0A6G7H7C1
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS10885
gene id: 1288484:G6R31_RS10885
uniprot id: A0A6G7H5D2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

1288484:G6R31 RS15315
gene id: 1288484:G6R31_RS15315
uniprot id: A0A6G7H8A2
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1288484:G6R31 RS00700
gene id: 1288484:G6R31_RS00700
uniprot id: A0A6G7H0W5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1288484:G6R31 RS03305
gene id: 1288484:G6R31_RS03305
uniprot id: A0A6G7H261
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1288484:G6R31 RS08370
gene id: 1288484:G6R31_RS08370
uniprot id: A0A6G7H4U4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1288484:G6R31 RS10575
gene id: 1288484:G6R31_RS10575
uniprot id: A0A6G7H5U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

1288484:G6R31 RS11935
gene id: 1288484:G6R31_RS11935
uniprot id: A0A6G7H5S6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1288484:G6R31 RS14820
gene id: 1288484:G6R31_RS14820
uniprot id: A0A6G7H888
names: Similarity
messages: Belongs to the peptidase S24 family.

1288484:G6R31 RS04570
gene id: 1288484:G6R31_RS04570
uniprot id: A0A6G7H7M5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1288484:G6R31 RS06560
gene id: 1288484:G6R31_RS06560
uniprot id: A0A6G7H3Z8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1288484:G6R31 RS11920
gene id: 1288484:G6R31_RS11920
uniprot id: A0A6G7H5S9
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1288484:G6R31 RS11820
gene id: 1288484:G6R31_RS11820
uniprot id: A0A6G7H621
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS16365
gene id: 1288484:G6R31_RS16365
uniprot id: A0A6G7H973
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

1288484:G6R31 RS09925
gene id: 1288484:G6R31_RS09925
uniprot id: A0A6G7H5M8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

1288484:G6R31 RS05525
gene id: 1288484:G6R31_RS05525
uniprot id: A0A6G7H3I1
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS13110
gene id: 1288484:G6R31_RS13110
uniprot id: A0A6G7H7F1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1288484:G6R31 RS01625
gene id: 1288484:G6R31_RS01625
uniprot id: A0A6G7H1J8
names: Similarity
messages: Belongs to the fabD family.

1288484:G6R31 RS00165
gene id: 1288484:G6R31_RS00165
uniprot id: A0A6G7H0P4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1288484:G6R31 RS15380
gene id: 1288484:G6R31_RS15380
uniprot id: A0A6G7H8B1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1288484:G6R31 RS08315
gene id: 1288484:G6R31_RS08315
uniprot id: A0A6G7H7U3
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

1288484:G6R31 RS07235
gene id: 1288484:G6R31_RS07235
uniprot id: A0A6G7H473
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1288484:G6R31 RS05425
gene id: 1288484:G6R31_RS05425
uniprot id: A0A6G7H3B0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1288484:G6R31 RS13465
gene id: 1288484:G6R31_RS13465
uniprot id: A0A6G7H6H7
names: Similarity
messages: Belongs to the UPF0102 family.

1288484:G6R31 RS14315
gene id: 1288484:G6R31_RS14315
uniprot id: A0A6G7H8B5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1288484:G6R31 RS13230
gene id: 1288484:G6R31_RS13230
uniprot id: A0A6G7H6D8
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS06280
gene id: 1288484:G6R31_RS06280
uniprot id: A0A6G7H3T5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1288484:G6R31 RS00685
gene id: 1288484:G6R31_RS00685
uniprot id: A0A6G7H0L2
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS02370
gene id: 1288484:G6R31_RS02370
uniprot id: A0A6G7H267
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1288484:G6R31 RS08970
gene id: 1288484:G6R31_RS08970
uniprot id: A0A6G7H4D4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1288484:G6R31 RS05815
gene id: 1288484:G6R31_RS05815
uniprot id: A0A6G7H365
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1288484:G6R31 RS05300
gene id: 1288484:G6R31_RS05300
uniprot id: A0A6G7H366
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1288484:G6R31 RS07955
gene id: 1288484:G6R31_RS07955
uniprot id: A0A6G7H3U4
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1288484:G6R31 RS00290
gene id: 1288484:G6R31_RS00290
uniprot id: A0A6G7H069
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1288484:G6R31 RS00190
gene id: 1288484:G6R31_RS00190
uniprot id: A0A6G7H051
names: Similarity
messages: Belongs to the ETF-QO/FixC family.

1288484:G6R31 RS07310
gene id: 1288484:G6R31_RS07310
uniprot id: A0A6G7H3K3
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

1288484:G6R31 RS03445
gene id: 1288484:G6R31_RS03445
uniprot id: A0A6G7H1Z2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1288484:G6R31 RS00755
gene id: 1288484:G6R31_RS00755
uniprot id: A0A6G7H0X5
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1288484:G6R31 RS05510
gene id: 1288484:G6R31_RS05510
uniprot id: A0A6G7H2P0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1288484:G6R31 RS03050
gene id: 1288484:G6R31_RS03050
uniprot id: A0A6G7H1F3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1288484:G6R31 RS07000
gene id: 1288484:G6R31_RS07000
uniprot id: A0A6G7H3E5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS07345
gene id: 1288484:G6R31_RS07345
uniprot id: A0A6G7H7N0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1288484:G6R31 RS04455
gene id: 1288484:G6R31_RS04455
uniprot id: A0A6G7H2R8
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS05290
gene id: 1288484:G6R31_RS05290
uniprot id: A0A6G7H390
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

1288484:G6R31 RS02895
gene id: 1288484:G6R31_RS02895
uniprot id: A0A6G7H206
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS10910
gene id: 1288484:G6R31_RS10910
uniprot id: A0A6G7H587
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

1288484:G6R31 RS02510
gene id: 1288484:G6R31_RS02510
uniprot id: A0A6G7H150
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1288484:G6R31 RS01610
gene id: 1288484:G6R31_RS01610
uniprot id: A0A6G7H0P7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1288484:G6R31 RS02835
gene id: 1288484:G6R31_RS02835
uniprot id: A0A6G7H1N3
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS02490
gene id: 1288484:G6R31_RS02490
uniprot id: A0A6G7H146
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

1288484:G6R31 RS10700
gene id: 1288484:G6R31_RS10700
uniprot id: A0A6G7H5W2
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1288484:G6R31 RS12100
gene id: 1288484:G6R31_RS12100
uniprot id: A0A6G7H5T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1288484:G6R31 RS10995
gene id: 1288484:G6R31_RS10995
uniprot id: A0A6G7H5F2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1288484:G6R31 RS10500
gene id: 1288484:G6R31_RS10500
uniprot id: A0A6G7H5E9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1288484:G6R31 RS07680
gene id: 1288484:G6R31_RS07680
uniprot id: A0A6G7H3Q9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1288484:G6R31 RS06790
gene id: 1288484:G6R31_RS06790
uniprot id: A0A6G7H438
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1288484:G6R31 RS05270
gene id: 1288484:G6R31_RS05270
uniprot id: A0A6G7H3E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1288484:G6R31 RS02795
gene id: 1288484:G6R31_RS02795
uniprot id: A0A6G7H227
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1288484:G6R31 RS01350
gene id: 1288484:G6R31_RS01350
uniprot id: A0A6G7H0X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1288484:G6R31 RS00500
gene id: 1288484:G6R31_RS00500
uniprot id: A0A6G7H197
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1288484:G6R31 RS12740
gene id: 1288484:G6R31_RS12740
uniprot id: A0A6G7H684
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1288484:G6R31 RS08555
gene id: 1288484:G6R31_RS08555
uniprot id: A0A6G7H489
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

1288484:G6R31 RS01660
gene id: 1288484:G6R31_RS01660
uniprot id: A0A6G7H0U8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1288484:G6R31 RS10745
gene id: 1288484:G6R31_RS10745
uniprot id: A0A6G7H558
names: Similarity
messages: Belongs to the TrpF family.

1288484:G6R31 RS11750
gene id: 1288484:G6R31_RS11750
uniprot id: A0A6G7H5P6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1288484:G6R31 RS06455
gene id: 1288484:G6R31_RS06455
uniprot id: A0A6G7H339
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1288484:G6R31 RS00140
gene id: 1288484:G6R31_RS00140
uniprot id: A0A6G7H137
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.

1288484:G6R31 RS13480
gene id: 1288484:G6R31_RS13480
uniprot id: A0A6G7H6H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1288484:G6R31 RS08040
gene id: 1288484:G6R31_RS08040
uniprot id: A0A6G7H401
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1288484:G6R31 RS00800
gene id: 1288484:G6R31_RS00800
uniprot id: A0A6G7H0N2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1288484:G6R31 RS00725
gene id: 1288484:G6R31_RS00725
uniprot id: A0A6G7H149
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1288484:G6R31 RS07565
gene id: 1288484:G6R31_RS07565
uniprot id: A0A6G7H3N9
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1288484:G6R31 RS06140
gene id: 1288484:G6R31_RS06140
uniprot id: A0A6G7H3B5
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1288484:G6R31 RS00215
gene id: 1288484:G6R31_RS00215
uniprot id: A0A6G7H017
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

1288484:G6R31 RS13100
gene id: 1288484:G6R31_RS13100
uniprot id: A0A6G7H6E4
names: Similarity
messages: Belongs to the asparaginase 1 family.

1288484:G6R31 RS10060
gene id: 1288484:G6R31_RS10060
uniprot id: A0A6G7H750
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1288484:G6R31 RS02575
gene id: 1288484:G6R31_RS02575
uniprot id: A0A6G7H1Y7
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

1288484:G6R31 RS03335
gene id: 1288484:G6R31_RS03335
uniprot id: A0A6G7H1K3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS04520
gene id: 1288484:G6R31_RS04520
uniprot id: A0A6G7H2S8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS15670
gene id: 1288484:G6R31_RS15670
uniprot id: A0A6G7H8J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1288484:G6R31 RS05450
gene id: 1288484:G6R31_RS05450
uniprot id: A0A6G7H3S7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS07175
gene id: 1288484:G6R31_RS07175
uniprot id: A0A6G7H3U8
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1288484:G6R31 RS06275
gene id: 1288484:G6R31_RS06275
uniprot id: A0A6G7H7R6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1288484:G6R31 RS08665
gene id: 1288484:G6R31_RS08665
uniprot id: A0A6G7H491
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS14785
gene id: 1288484:G6R31_RS14785
uniprot id: A0A6G7H818
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.

1288484:G6R31 RS01430
gene id: 1288484:G6R31_RS01430
uniprot id: A0A6G7H184
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS12725
gene id: 1288484:G6R31_RS12725
uniprot id: A0A6G7H6U7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1288484:G6R31 RS01020
gene id: 1288484:G6R31_RS01020
uniprot id: A0A6G7H161
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1288484:G6R31 RS01620
gene id: 1288484:G6R31_RS01620
uniprot id: A0A6G7H0Q3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1288484:G6R31 RS16105
gene id: 1288484:G6R31_RS16105
uniprot id: A0A6G7H9R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

1288484:G6R31 RS01640
gene id: 1288484:G6R31_RS01640
uniprot id: A0A6G7H1D6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1288484:G6R31 RS00710
gene id: 1288484:G6R31_RS00710
uniprot id: A0A6G7H0A2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1288484:G6R31 RS03385
gene id: 1288484:G6R31_RS03385
uniprot id: A0A6G7H2F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1288484:G6R31 RS03370
gene id: 1288484:G6R31_RS03370
uniprot id: A0A6G7H1K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1288484:G6R31 RS15200
gene id: 1288484:G6R31_RS15200
uniprot id: A0A6G7H8Z2
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS09375
gene id: 1288484:G6R31_RS09375
uniprot id: A0A6G7H4M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1288484:G6R31 RS05295
gene id: 1288484:G6R31_RS05295
uniprot id: A0A6G7H3C2
names: Similarity
messages: Belongs to the ComB family.

1288484:G6R31 RS08630
gene id: 1288484:G6R31_RS08630
uniprot id: A0A6G7H462
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1288484:G6R31 RS12225
gene id: 1288484:G6R31_RS12225
uniprot id: A0A6G7H682
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1288484:G6R31 RS09915
gene id: 1288484:G6R31_RS09915
uniprot id: A0A6G7H5Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

1288484:G6R31 RS00730
gene id: 1288484:G6R31_RS00730
uniprot id: A0A6G7H0A1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1288484:G6R31 RS10715
gene id: 1288484:G6R31_RS10715
uniprot id: A0A6G7H5S5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1288484:G6R31 RS10610
gene id: 1288484:G6R31_RS10610
uniprot id: A0A6G7H5Y7
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1288484:G6R31 RS00940
gene id: 1288484:G6R31_RS00940
uniprot id: A0A6G7H0I0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1288484:G6R31 RS13495
gene id: 1288484:G6R31_RS13495
uniprot id: A0A6G7H6F5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1288484:G6R31 RS12685
gene id: 1288484:G6R31_RS12685
uniprot id: A0A6G7H674
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1288484:G6R31 RS05460
gene id: 1288484:G6R31_RS05460
uniprot id: A0A6G7H7N1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1288484:G6R31 RS10175
gene id: 1288484:G6R31_RS10175
uniprot id: A0A6G7H5A1
names: Similarity
messages: Belongs to the NAPRTase family.

1288484:G6R31 RS10410
gene id: 1288484:G6R31_RS10410
uniprot id: A0A6G7H5V8
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

1288484:G6R31 RS08705
gene id: 1288484:G6R31_RS08705
uniprot id: A0A6G7H505
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

1288484:G6R31 RS11595
gene id: 1288484:G6R31_RS11595
uniprot id: A0A6G7H6B3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1288484:G6R31 RS13320
gene id: 1288484:G6R31_RS13320
uniprot id: A0A6G7H766
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1288484:G6R31 RS07050
gene id: 1288484:G6R31_RS07050
uniprot id: A0A6G7H3F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1288484:G6R31 RS05650
gene id: 1288484:G6R31_RS05650
uniprot id: A0A6G7H335
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1288484:G6R31 RS00400
gene id: 1288484:G6R31_RS00400
uniprot id: A0A6G7H045
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1288484:G6R31 RS00740
gene id: 1288484:G6R31_RS00740
uniprot id: A0A6G7H0Y9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1288484:G6R31 RS12920
gene id: 1288484:G6R31_RS12920
uniprot id: A0A6G7H6Z6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1288484:G6R31 RS11655
gene id: 1288484:G6R31_RS11655
uniprot id: A0A6G7H685
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1288484:G6R31 RS05505
gene id: 1288484:G6R31_RS05505
uniprot id: A0A6G7H2S9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1288484:G6R31 RS14970
gene id: 1288484:G6R31_RS14970
uniprot id: A0A6G7H812
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

1288484:G6R31 RS09715
gene id: 1288484:G6R31_RS09715
uniprot id: A0A6G7H523
names: Similarity
messages: Belongs to the asp23 family.

1288484:G6R31 RS09450
gene id: 1288484:G6R31_RS09450
uniprot id: A0A6G7H4L4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1288484:G6R31 RS10580
gene id: 1288484:G6R31_RS10580
uniprot id: A0A6G7H5W0
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1288484:G6R31 RS03540
gene id: 1288484:G6R31_RS03540
uniprot id: A0A6G7H1N1
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1288484:G6R31 RS09080
gene id: 1288484:G6R31_RS09080
uniprot id: A0A6G7H4G1
names: Similarity
messages: Belongs to the RimK family. LysX subfamily.

1288484:G6R31 RS04565
gene id: 1288484:G6R31_RS04565
uniprot id: A0A6G7H2V7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1288484:G6R31 RS00620
gene id: 1288484:G6R31_RS00620
uniprot id: A0A6G7H081
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

1288484:G6R31 RS14490
gene id: 1288484:G6R31_RS14490
uniprot id: A0A6G7H7U2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1288484:G6R31 RS01130
gene id: 1288484:G6R31_RS01130
uniprot id: A0A6G7H6Q5
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS07045
gene id: 1288484:G6R31_RS07045
uniprot id: A0A6G7H3I6
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

1288484:G6R31 RS12545
gene id: 1288484:G6R31_RS12545
uniprot id: A0A6G7H761
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS06940
gene id: 1288484:G6R31_RS06940
uniprot id: A0A6G7H3D5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1288484:G6R31 RS10490
gene id: 1288484:G6R31_RS10490
uniprot id: A0A6G7H5W8
names: Similarity
messages: Belongs to the peptidase S13 family.

1288484:G6R31 RS10480
gene id: 1288484:G6R31_RS10480
uniprot id: A0A6G7H820
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1288484:G6R31 RS08235
gene id: 1288484:G6R31_RS08235
uniprot id: A0A6G7H4C6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1288484:G6R31 RS05985
gene id: 1288484:G6R31_RS05985
uniprot id: A0A6G7H416
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

1288484:G6R31 RS13880
gene id: 1288484:G6R31_RS13880
uniprot id: A0A6G7H7S9
names: Similarity
messages: Belongs to the peptidase S45 family.

1288484:G6R31 RS10515
gene id: 1288484:G6R31_RS10515
uniprot id: A0A6G7H5P5
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1288484:G6R31 RS07665
gene id: 1288484:G6R31_RS07665
uniprot id: A0A6G7H3U3
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS00715
gene id: 1288484:G6R31_RS00715
uniprot id: A0A6G7H1D7
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1288484:G6R31 RS01280
gene id: 1288484:G6R31_RS01280
uniprot id: A0A6G7H0J6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1288484:G6R31 RS07765
gene id: 1288484:G6R31_RS07765
uniprot id: A0A0D5Z8R8
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1288484:G6R31 RS13060
gene id: 1288484:G6R31_RS13060
uniprot id: A0A6G7H6A9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1288484:G6R31 RS12340
gene id: 1288484:G6R31_RS12340
uniprot id: A0A6G7H6N2
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS15195
gene id: 1288484:G6R31_RS15195
uniprot id: A0A6G7H852
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS10800
gene id: 1288484:G6R31_RS10800
uniprot id: A0A6G7H568
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1288484:G6R31 RS12220
gene id: 1288484:G6R31_RS12220
uniprot id: A0A6G7H5V1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1288484:G6R31 RS09845
gene id: 1288484:G6R31_RS09845
uniprot id: A0A6G7H4V9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1288484:G6R31 RS03070
gene id: 1288484:G6R31_RS03070
uniprot id: A0A6G7H220
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1288484:G6R31 RS14665
gene id: 1288484:G6R31_RS14665
uniprot id: A0A6G7H7X1
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1288484:G6R31 RS14210
gene id: 1288484:G6R31_RS14210
uniprot id: A0A6G7H8H1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1288484:G6R31 RS07300
gene id: 1288484:G6R31_RS07300
uniprot id: A0A6G7H451
names: Cofactor
messages: The heme is bound between the two transmembrane subunits.

1288484:G6R31 RS08865
gene id: 1288484:G6R31_RS08865
uniprot id: A0A6G7H4B6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1288484:G6R31 RS03430
gene id: 1288484:G6R31_RS03430
uniprot id: A0A6G7H1M2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1288484:G6R31 RS11505
gene id: 1288484:G6R31_RS11505
uniprot id: A0A6G7H6P0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-66 and Arg-69) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

1288484:G6R31 RS03395
gene id: 1288484:G6R31_RS03395
uniprot id: A0A6G7H1Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1288484:G6R31 RS13385
gene id: 1288484:G6R31_RS13385
uniprot id: A0A6G7H758
names: Similarity
messages: Belongs to the CutA family.

1288484:G6R31 RS13205
gene id: 1288484:G6R31_RS13205
uniprot id: A0A6G7H747
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1288484:G6R31 RS08345
gene id: 1288484:G6R31_RS08345
uniprot id: A0A6G7H413
names: Similarity
messages: Belongs to the peptidase S1C family.

1288484:G6R31 RS01085
gene id: 1288484:G6R31_RS01085
uniprot id: A0A6G7H0G1
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

1288484:G6R31 RS10120
gene id: 1288484:G6R31_RS10120
uniprot id: A0A6G7H5L7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1288484:G6R31 RS04655
gene id: 1288484:G6R31_RS04655
uniprot id: A0A6G7H332
names: Subcellular Location Annotation
messages: Cytoplasm

1288484:G6R31 RS15070
gene id: 1288484:G6R31_RS15070
uniprot id: A0A6G7H837
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1288484:G6R31 RS12490
gene id: 1288484:G6R31_RS12490
uniprot id: A0A6G7H752
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1288484:G6R31 RS03745
gene id: 1288484:G6R31_RS03745
uniprot id: A0A6G7H2F8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1288484:G6R31 RS05780
gene id: 1288484:G6R31_RS05780
uniprot id: A0A6G7H3E6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1288484:G6R31 RS06395
gene id: 1288484:G6R31_RS06395
uniprot id: A0A6G7H330
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS11155
gene id: 1288484:G6R31_RS11155
uniprot id: A0A6G7H5Q6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS01140
gene id: 1288484:G6R31_RS01140
uniprot id: A0A6G7H0K7
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS08525
gene id: 1288484:G6R31_RS08525
uniprot id: A0A6G7H4Z0
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

1288484:G6R31 RS05965
gene id: 1288484:G6R31_RS05965
uniprot id: A0A6G7H306
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS00495
gene id: 1288484:G6R31_RS00495
uniprot id: A0A6G7H061
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

1288484:G6R31 RS06155
gene id: 1288484:G6R31_RS06155
uniprot id: A0A6G7H3N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1288484:G6R31 RS11680
gene id: 1288484:G6R31_RS11680
uniprot id: A0A6G7H6G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1288484:G6R31 RS03440
gene id: 1288484:G6R31_RS03440
uniprot id: A0A6G7H1M4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 15 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1288484:G6R31 RS00735
gene id: 1288484:G6R31_RS00735
uniprot id: A0A6G7H0M2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1288484:G6R31 RS07320
gene id: 1288484:G6R31_RS07320
uniprot id: A0A6G7H4P7
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1288484:G6R31 RS13530
gene id: 1288484:G6R31_RS13530
uniprot id: A0A6G7H6I7
names: Similarity
messages: Belongs to the Dps family.

1288484:G6R31 RS04495
gene id: 1288484:G6R31_RS04495
uniprot id: A0A6G7H762
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1288484:G6R31 RS13450
gene id: 1288484:G6R31_RS13450
uniprot id: A0A6G7H785
names: Similarity
messages: Belongs to the Nth/MutY family.

1288484:G6R31 RS09200
gene id: 1288484:G6R31_RS09200
uniprot id: A0A6G7H4J9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1288484:G6R31 RS09150
gene id: 1288484:G6R31_RS09150
uniprot id: A0A6G7H7W3
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1288484:G6R31 RS09015
gene id: 1288484:G6R31_RS09015
uniprot id: A0A6G7H4Z2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1288484:G6R31 RS09455
gene id: 1288484:G6R31_RS09455
uniprot id: A0A6G7H5E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1288484:G6R31 RS14700
gene id: 1288484:G6R31_RS14700
uniprot id: A0A6G7H900
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1288484:G6R31 RS05610
gene id: 1288484:G6R31_RS05610
uniprot id: A0A6G7H3B6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1288484:G6R31 RS11430
gene id: 1288484:G6R31_RS11430
uniprot id: A0A6G7H5K3
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1288484:G6R31 RS09445
gene id: 1288484:G6R31_RS09445
uniprot id: A0A6G7H5Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease PrsW family.
messages: Cell membrane
messages: Membrane

1288484:G6R31 RS02645
gene id: 1288484:G6R31_RS02645
uniprot id: A0A6G7H1B9
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1288484:G6R31 RS08805
gene id: 1288484:G6R31_RS08805
uniprot id: A0A6G7H4A5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1288484:G6R31 RS10340
gene id: 1288484:G6R31_RS10340
uniprot id: A0A6G7H4Z9
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1288484:G6R31 RS09875
gene id: 1288484:G6R31_RS09875
uniprot id: A0A6G7H4R7
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1288484:G6R31 RS05415
gene id: 1288484:G6R31_RS05415
uniprot id: A0A6G7H2M1
names: Similarity
messages: Belongs to the TrpC family.

1288484:G6R31 RS11555
gene id: 1288484:G6R31_RS11555
uniprot id: A0A6G7H5P1
names: Similarity
messages: Belongs to the UPF0173 family.

1288484:G6R31 RS11175
gene id: 1288484:G6R31_RS11175
uniprot id: A0A6G7H5I1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1288484:G6R31 RS06720
gene id: 1288484:G6R31_RS06720
uniprot id: A0A6G7H394
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1288484:G6R31 RS05645
gene id: 1288484:G6R31_RS05645
uniprot id: A0A6G7H2R1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1288484:G6R31 RS13075
gene id: 1288484:G6R31_RS13075
uniprot id: A0A6G7H6M0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1288484:G6R31 RS06270
gene id: 1288484:G6R31_RS06270
uniprot id: A0A6G7H3Q3
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1288484:G6R31 RS01680
gene id: 1288484:G6R31_RS01680
uniprot id: A0A6G7H1K8
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1288484:G6R31 RS09185
gene id: 1288484:G6R31_RS09185
uniprot id: A0A6G7H556
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1288484:G6R31 RS05635
gene id: 1288484:G6R31_RS05635
uniprot id: A0A6G7H3K1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1288484:G6R31 RS16380
gene id: 1288484:G6R31_RS16380
uniprot id: A0A6G7H9X2
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

1288484:G6R31 RS12155
gene id: 1288484:G6R31_RS12155
uniprot id: A0A6G7H6N8
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

1288484:G6R31 RS06690
gene id: 1288484:G6R31_RS06690
uniprot id: A0A6G7H3X0
names: Similarity
messages: Belongs to the BshC family.

1288484:G6R31 RS06535
gene id: 1288484:G6R31_RS06535
uniprot id: A0A6G7H397
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1288484:G6R31 RS08035
gene id: 1288484:G6R31_RS08035
uniprot id: A0A6G7H4H2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1288484:G6R31 RS04055
gene id: 1288484:G6R31_RS04055
uniprot id: A0A6G7H322
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1288484:G6R31 RS00975
gene id: 1288484:G6R31_RS00975
uniprot id: A0A6G7H7B0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1288484:G6R31 RS08570
gene id: 1288484:G6R31_RS08570
uniprot id: A0A6G7H464
names: Similarity
messages: Belongs to the P(II) protein family.

1288484:G6R31 RS00920
gene id: 1288484:G6R31_RS00920
uniprot id: A0A6G7H117
names: Similarity
messages: Belongs to the asp23 family.

1288484:G6R31 RS03190
gene id: 1288484:G6R31_RS03190
uniprot id: A0A6G7H241
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1288484:G6R31 RS07715
gene id: 1288484:G6R31_RS07715
uniprot id: A0A6G7H4I3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1288484:G6R31 RS10555
gene id: 1288484:G6R31_RS10555
uniprot id: A0A6G7H530
names: Similarity
messages: Belongs to the peptidase S9C family.

1288484:G6R31 RS09695
gene id: 1288484:G6R31_RS09695
uniprot id: A0A6G7H4Q5
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

1288484:G6R31 RS04435
gene id: 1288484:G6R31_RS04435
uniprot id: A0A6G7H253
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1288484:G6R31 RS11410
gene id: 1288484:G6R31_RS11410
uniprot id: A0A6G7H699
names: Caution
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1288484:G6R31 RS01615
gene id: 1288484:G6R31_RS01615
uniprot id: A0A6G7H1T8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1288484:G6R31 RS16230
gene id: 1288484:G6R31_RS16230
uniprot id: A0A6G7H8U2
names: Similarity
messages: Belongs to the WrbA family.

1288484:G6R31 RS00105
gene id: 1288484:G6R31_RS00105
uniprot id: A0A6G7H0N4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1288484:G6R31 RS10255
gene id: 1288484:G6R31_RS10255
uniprot id: A0A6G7H7Z5
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1288484:G6R31 RS03410
gene id: 1288484:G6R31_RS03410
uniprot id: A0A6G7H281
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 15 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1288484:G6R31 RS08175
gene id: 1288484:G6R31_RS08175
uniprot id: A0A6G7H3Y3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS11030
gene id: 1288484:G6R31_RS11030
uniprot id: A0A6G7H5N8
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS11120
gene id: 1288484:G6R31_RS11120
uniprot id: A0A6G7H5H2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1288484:G6R31 RS08310
gene id: 1288484:G6R31_RS08310
uniprot id: A0A6G7H449
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

1288484:G6R31 RS10710
gene id: 1288484:G6R31_RS10710
uniprot id: A0A6G7H5Y0
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1288484:G6R31 RS12110
gene id: 1288484:G6R31_RS12110
uniprot id: A0A6G7H6J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1288484:G6R31 RS09955
gene id: 1288484:G6R31_RS09955
uniprot id: A0A6G7H5F5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1288484:G6R31 RS07670
gene id: 1288484:G6R31_RS07670
uniprot id: A0A6G7H3R5
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS01330
gene id: 1288484:G6R31_RS01330
uniprot id: A0A6G7H1N8
names: Similarity
messages: Belongs to the peptidase S66 family.

1288484:G6R31 RS02925
gene id: 1288484:G6R31_RS02925
uniprot id: A0A6G7H1D4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1288484:G6R31 RS13940
gene id: 1288484:G6R31_RS13940
uniprot id: A0A6G7H869
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1288484:G6R31 RS06660
gene id: 1288484:G6R31_RS06660
uniprot id: A0A6G7H4C8
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1288484:G6R31 RS00660
gene id: 1288484:G6R31_RS00660
uniprot id: A0A6G7H1C7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1288484:G6R31 RS08125
gene id: 1288484:G6R31_RS08125
uniprot id: A0A6G7H3X3
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1288484:G6R31 RS12400
gene id: 1288484:G6R31_RS12400
uniprot id: A0A6G7H6R7
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

1288484:G6R31 RS00090
gene id: 1288484:G6R31_RS00090
uniprot id: A0A6G7GZZ7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1288484:G6R31 RS00055
gene id: 1288484:G6R31_RS00055
uniprot id: A0A6G7H0Q1
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Periplasm

1288484:G6R31 RS01040
gene id: 1288484:G6R31_RS01040
uniprot id: A0A6G7H1I7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1288484:G6R31 RS06785
gene id: 1288484:G6R31_RS06785
uniprot id: A0A6G7H399
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1288484:G6R31 RS08790
gene id: 1288484:G6R31_RS08790
uniprot id: A0A6G7H4C7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1288484:G6R31 RS13030
gene id: 1288484:G6R31_RS13030
uniprot id: A0A6G7H6Z8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1288484:G6R31 RS07550
gene id: 1288484:G6R31_RS07550
uniprot id: A0A6G7H3S3
names: Subcellular Location Annotation
messages: Cytoplasm

1288484:G6R31 RS16720
gene id: 1288484:G6R31_RS16720
uniprot id: A0A6G7H957
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

1288484:G6R31 RS14865
gene id: 1288484:G6R31_RS14865
uniprot id: A0A6G7H7X0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1288484:G6R31 RS07270
gene id: 1288484:G6R31_RS07270
uniprot id: A0A6G7H3I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1288484:G6R31 RS08650
gene id: 1288484:G6R31_RS08650
uniprot id: A0A6G7H4Z4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1288484:G6R31 RS16055
gene id: 1288484:G6R31_RS16055
uniprot id: A0A6G7H8M0
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

1288484:G6R31 RS09565
gene id: 1288484:G6R31_RS09565
uniprot id: A0A6G7H5G8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. Tam family.
messages: Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
messages: Cytoplasm

1288484:G6R31 RS02520
gene id: 1288484:G6R31_RS02520
uniprot id: A0A6G7H1T5
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS10955
gene id: 1288484:G6R31_RS10955
uniprot id: A0A6G7H5B7
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1288484:G6R31 RS11130
gene id: 1288484:G6R31_RS11130
uniprot id: A0A6G7H6H9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1288484:G6R31 RS16735
gene id: 1288484:G6R31_RS16735
uniprot id: A0A6G7H909
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1288484:G6R31 RS01475
gene id: 1288484:G6R31_RS01475
uniprot id: A0A6G7H1E5
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1288484:G6R31 RS13020
gene id: 1288484:G6R31_RS13020
uniprot id: A0A6G7H6K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1288484:G6R31 RS07150
gene id: 1288484:G6R31_RS07150
uniprot id: A0A6G7H3H5
names: Similarity
messages: Belongs to the peptidase S1C family.

1288484:G6R31 RS01760
gene id: 1288484:G6R31_RS01760
uniprot id: A0A6G7H0R8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1288484:G6R31 RS12165
gene id: 1288484:G6R31_RS12165
uniprot id: A0A6G7H671
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily.

1288484:G6R31 RS15160
gene id: 1288484:G6R31_RS15160
uniprot id: A0A6G7H8V5
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS15405
gene id: 1288484:G6R31_RS15405
uniprot id: A0A6G7H942
names: Similarity
messages: Belongs to the transposase 7 family.

1288484:G6R31 RS07220
gene id: 1288484:G6R31_RS07220
uniprot id: A0A6G7H4B8
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1288484:G6R31 RS02690
gene id: 1288484:G6R31_RS02690
uniprot id: A0A6G7H1W6
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS16160
gene id: 1288484:G6R31_RS16160
uniprot id: A0A6G7H8T0
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1288484:G6R31 RS14765
gene id: 1288484:G6R31_RS14765
uniprot id: A0A6G7H878
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

1288484:G6R31 RS07925
gene id: 1288484:G6R31_RS07925
uniprot id: A0A6G7H4F2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit.

1288484:G6R31 RS13905
gene id: 1288484:G6R31_RS13905
uniprot id: A0A6G7H7L6
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS00065
gene id: 1288484:G6R31_RS00065
uniprot id: A0A6G7H038
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1288484:G6R31 RS12650
gene id: 1288484:G6R31_RS12650
uniprot id: A0A6G7H6F1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

1288484:G6R31 RS03685
gene id: 1288484:G6R31_RS03685
uniprot id: A0A6G7H232
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1288484:G6R31 RS14190
gene id: 1288484:G6R31_RS14190
uniprot id: A0A6G7H7P4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1288484:G6R31 RS05745
gene id: 1288484:G6R31_RS05745
uniprot id: A0A6G7H2S7
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1288484:G6R31 RS12205
gene id: 1288484:G6R31_RS12205
uniprot id: A0A6G7H701
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane.

1288484:G6R31 RS10090
gene id: 1288484:G6R31_RS10090
uniprot id: A0A6G7H4Y0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1288484:G6R31 RS09550
gene id: 1288484:G6R31_RS09550
uniprot id: A0A6G7H4P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1288484:G6R31 RS01275
gene id: 1288484:G6R31_RS01275
uniprot id: A0A6G7H1M9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1288484:G6R31 RS05275
gene id: 1288484:G6R31_RS05275
uniprot id: A0A0D5Z9C8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1288484:G6R31 RS00325
gene id: 1288484:G6R31_RS00325
uniprot id: A0A6G7H0S3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS04615
gene id: 1288484:G6R31_RS04615
uniprot id: A0A6G7H2K3
names: Similarity
messages: Belongs to the peptidase C40 family.

1288484:G6R31 RS00655
gene id: 1288484:G6R31_RS00655
uniprot id: A0A6G7H092
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1288484:G6R31 RS08185
gene id: 1288484:G6R31_RS08185
uniprot id: A0A6G7H4B5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1288484:G6R31 RS04650
gene id: 1288484:G6R31_RS04650
uniprot id: A0A6G7H290
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.

1288484:G6R31 RS14440
gene id: 1288484:G6R31_RS14440
uniprot id: A0A6G7H7T2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

1288484:G6R31 RS05875
gene id: 1288484:G6R31_RS05875
uniprot id: A0A6G7H2V2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1288484:G6R31 RS01155
gene id: 1288484:G6R31_RS01155
uniprot id: A0A6G7H0H8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably interacts with PlsX.

1288484:G6R31 RS00795
gene id: 1288484:G6R31_RS00795
uniprot id: A0A6G7H7H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

1288484:G6R31 RS01025
gene id: 1288484:G6R31_RS01025
uniprot id: A0A6G7H114
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1288484:G6R31 RS09910
gene id: 1288484:G6R31_RS09910
uniprot id: A0A6G7H4V1
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1288484:G6R31 RS13710
gene id: 1288484:G6R31_RS13710
uniprot id: A0A6G7H770
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.

1288484:G6R31 RS06265
gene id: 1288484:G6R31_RS06265
uniprot id: A0A6G7H3D4
names: Similarity
messages: Belongs to the GSP E family.

1288484:G6R31 RS00750
gene id: 1288484:G6R31_RS00750
uniprot id: A0A6G7H121
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1288484:G6R31 RS02065
gene id: 1288484:G6R31_RS02065
uniprot id: A0A6G7H191
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1288484:G6R31 RS14185
gene id: 1288484:G6R31_RS14185
uniprot id: A0A6G7H7R7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1288484:G6R31 RS05385
gene id: 1288484:G6R31_RS05385
uniprot id: A0A6G7H2Q8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. LysZ subfamily.
messages: Catalyzes the phosphorylation of LysW-gamma-alpha-aminoadipate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS05530
gene id: 1288484:G6R31_RS05530
uniprot id: A0A6G7H2P1
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS01090
gene id: 1288484:G6R31_RS01090
uniprot id: A0A6G7H1J7
names: Similarity
messages: Belongs to the glutamine synthetase family.

1288484:G6R31 RS10585
gene id: 1288484:G6R31_RS10585
uniprot id: A0A6G7H5Q5
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1288484:G6R31 RS10455
gene id: 1288484:G6R31_RS10455
uniprot id: A0A6G7H563
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XseA family.
messages: Cytoplasm

1288484:G6R31 RS02985
gene id: 1288484:G6R31_RS02985
uniprot id: A0A6G7H285
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS07585
gene id: 1288484:G6R31_RS07585
uniprot id: A0A6G7H4D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1288484:G6R31 RS13770
gene id: 1288484:G6R31_RS13770
uniprot id: A0A6G7H6Q3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1288484:G6R31 RS02550
gene id: 1288484:G6R31_RS02550
uniprot id: A0A6G7H162
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1288484:G6R31 RS15010
gene id: 1288484:G6R31_RS15010
uniprot id: A0A6G7H857
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1288484:G6R31 RS02600
gene id: 1288484:G6R31_RS02600
uniprot id: A0A6G7H167
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1288484:G6R31 RS05405
gene id: 1288484:G6R31_RS05405
uniprot id: A0A6G7H3G2
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1288484:G6R31 RS11050
gene id: 1288484:G6R31_RS11050
uniprot id: A0A6G7H5Y5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1288484:G6R31 RS11630
gene id: 1288484:G6R31_RS11630
uniprot id: A0A6G7H6F8
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1288484:G6R31 RS14485
gene id: 1288484:G6R31_RS14485
uniprot id: A0A6G7H7W8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1288484:G6R31 RS09760
gene id: 1288484:G6R31_RS09760
uniprot id: A0A6G7H4R5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1288484:G6R31 RS09435
gene id: 1288484:G6R31_RS09435
uniprot id: A0A6G7H4N8
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

1288484:G6R31 RS00965
gene id: 1288484:G6R31_RS00965
uniprot id: A0A6G7H189
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS08030
gene id: 1288484:G6R31_RS08030
uniprot id: A0A6G7H4N3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS14505
gene id: 1288484:G6R31_RS14505
uniprot id: A0A6G7H8M2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1288484:G6R31 RS07850
gene id: 1288484:G6R31_RS07850
uniprot id: A0A6G7H769
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1288484:G6R31 RS10125
gene id: 1288484:G6R31_RS10125
uniprot id: A0A6G7H5P0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1288484:G6R31 RS06445
gene id: 1288484:G6R31_RS06445
uniprot id: A0A6G7H340
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1288484:G6R31 RS16115
gene id: 1288484:G6R31_RS16115
uniprot id: A0A6G7H9G0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1288484:G6R31 RS14660
gene id: 1288484:G6R31_RS14660
uniprot id: A0A6G7H7Z8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1288484:G6R31 RS13170
gene id: 1288484:G6R31_RS13170
uniprot id: A0A6G7H6C9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1288484:G6R31 RS06375
gene id: 1288484:G6R31_RS06375
uniprot id: A0A6G7H475
names: Similarity
messages: Belongs to the TelA family.

1288484:G6R31 RS12775
gene id: 1288484:G6R31_RS12775
uniprot id: A0A6G7H640
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1288484:G6R31 RS10770
gene id: 1288484:G6R31_RS10770
uniprot id: A0A6G7H5B1
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1288484:G6R31 RS11850
gene id: 1288484:G6R31_RS11850
uniprot id: A0A6G7H824
names: Similarity
messages: Belongs to the UPF0047 family.

1288484:G6R31 RS06960
gene id: 1288484:G6R31_RS06960
uniprot id: A0A6G7H3C8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metal hydrolase YfiT family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Possible metal-dependent hydrolase.

1288484:G6R31 RS11770
gene id: 1288484:G6R31_RS11770
uniprot id: A0A6G7H6E3
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1288484:G6R31 RS01150
gene id: 1288484:G6R31_RS01150
uniprot id: A0A6G7H1K7
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1288484:G6R31 RS14590
gene id: 1288484:G6R31_RS14590
uniprot id: A0A6G7H7W1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

1288484:G6R31 RS15335
gene id: 1288484:G6R31_RS15335
uniprot id: A0A6G7H915
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1288484:G6R31 RS07515
gene id: 1288484:G6R31_RS07515
uniprot id: A0A6G7H4G8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1288484:G6R31 RS11060
gene id: 1288484:G6R31_RS11060
uniprot id: A0A6G7H5E3
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1288484:G6R31 RS13270
gene id: 1288484:G6R31_RS13270
uniprot id: A0A6G7H6H4
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1288484:G6R31 RS01265
gene id: 1288484:G6R31_RS01265
uniprot id: A0A6G7H0M6
names: Similarity
messages: Belongs to the FBPase class 2 family.

1288484:G6R31 RS12115
gene id: 1288484:G6R31_RS12115
uniprot id: A0A6G7H6L4
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1288484:G6R31 RS02295
gene id: 1288484:G6R31_RS02295
uniprot id: A0A6G7H1N0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1288484:G6R31 RS03325
gene id: 1288484:G6R31_RS03325
uniprot id: A0A6G7H1K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1288484:G6R31 RS03365
gene id: 1288484:G6R31_RS03365
uniprot id: A0A6G7H1P6
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1288484:G6R31 RS09235
gene id: 1288484:G6R31_RS09235
uniprot id: A0A6G7H4U3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1288484:G6R31 RS11480
gene id: 1288484:G6R31_RS11480
uniprot id: A0A6G7H7E7
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1288484:G6R31 RS09145
gene id: 1288484:G6R31_RS09145
uniprot id: A0A6G7H4G4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1288484:G6R31 RS10370
gene id: 1288484:G6R31_RS10370
uniprot id: A0A6G7H5Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1288484:G6R31 RS00045
gene id: 1288484:G6R31_RS00045
uniprot id: A0A6G7H6L7
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Periplasm

1288484:G6R31 RS05335
gene id: 1288484:G6R31_RS05335
uniprot id: A0A6G7H6X8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

1288484:G6R31 RS06915
gene id: 1288484:G6R31_RS06915
uniprot id: A0A6G7H3P8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1288484:G6R31 RS01045
gene id: 1288484:G6R31_RS01045
uniprot id: A0A6G7H0F9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1288484:G6R31 RS10050
gene id: 1288484:G6R31_RS10050
uniprot id: A0A6G7H5P7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1288484:G6R31 RS12460
gene id: 1288484:G6R31_RS12460
uniprot id: A0A6G7H6C1
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS08715
gene id: 1288484:G6R31_RS08715
uniprot id: A0A6G7H4U2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1288484:G6R31 RS01840
gene id: 1288484:G6R31_RS01840
uniprot id: A0A6G7H1F0
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1288484:G6R31 RS06510
gene id: 1288484:G6R31_RS06510
uniprot id: A0A6G7H350
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS16455
gene id: 1288484:G6R31_RS16455
uniprot id: A0A6G7H952
names: Similarity
messages: Belongs to the HsdR family.

1288484:G6R31 RS11125
gene id: 1288484:G6R31_RS11125
uniprot id: A0A6G7H5F3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1288484:G6R31 RS14680
gene id: 1288484:G6R31_RS14680
uniprot id: A0A6G7H8Q2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1288484:G6R31 RS06075
gene id: 1288484:G6R31_RS06075
uniprot id: A0A6G7H2Y0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1288484:G6R31 RS15990
gene id: 1288484:G6R31_RS15990
uniprot id: A0A6G7H8Q0
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS05225
gene id: 1288484:G6R31_RS05225
uniprot id: A0A6G7H2W0
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1288484:G6R31 RS12485
gene id: 1288484:G6R31_RS12485
uniprot id: A0A6G7H616
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

1288484:G6R31 RS02245
gene id: 1288484:G6R31_RS02245
uniprot id: A0A6G7H145
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1288484:G6R31 RS06590
gene id: 1288484:G6R31_RS06590
uniprot id: A0A6G7H3A7
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1288484:G6R31 RS01555
gene id: 1288484:G6R31_RS01555
uniprot id: A0A6G7H0P3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1288484:G6R31 RS14940
gene id: 1288484:G6R31_RS14940
uniprot id: A0A6G7H8R3
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1288484:G6R31 RS10135
gene id: 1288484:G6R31_RS10135
uniprot id: A0A6G7H507
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1288484:G6R31 RS02990
gene id: 1288484:G6R31_RS02990
uniprot id: A0A6G7H1E3
names: Similarity
messages: Belongs to the peptidase M16 family.

1288484:G6R31 RS01645
gene id: 1288484:G6R31_RS01645
uniprot id: A0A6G7H1H6
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1288484:G6R31 RS00535
gene id: 1288484:G6R31_RS00535
uniprot id: A0A6G7H0Y1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1288484:G6R31 RS11395
gene id: 1288484:G6R31_RS11395
uniprot id: A0A6G7H5H0
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1288484:G6R31 RS10975
gene id: 1288484:G6R31_RS10975
uniprot id: A0A6G7H612
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1288484:G6R31 RS10895
gene id: 1288484:G6R31_RS10895
uniprot id: A0A6G7H6E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1288484:G6R31 RS13935
gene id: 1288484:G6R31_RS13935
uniprot id: A0A6G7H7T9
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1288484:G6R31 RS07600
gene id: 1288484:G6R31_RS07600
uniprot id: A0A6G7H4G3
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1288484:G6R31 RS08150
gene id: 1288484:G6R31_RS08150
uniprot id: A0A6G7H420
names: Similarity
messages: Belongs to the peptidase S58 family.

1288484:G6R31 RS08780
gene id: 1288484:G6R31_RS08780
uniprot id: A0A6G7H515
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1288484:G6R31 RS11740
gene id: 1288484:G6R31_RS11740
uniprot id: A0A6G7H5Q0
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS08140
gene id: 1288484:G6R31_RS08140
uniprot id: A0A6G7H4Q3
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

1288484:G6R31 RS12600
gene id: 1288484:G6R31_RS12600
uniprot id: A0A6G7H664
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1288484:G6R31 RS16000
gene id: 1288484:G6R31_RS16000
uniprot id: A0A6G7H9P6
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1288484:G6R31 RS08010
gene id: 1288484:G6R31_RS08010
uniprot id: A0A6G7H487
names: Similarity
messages: Belongs to the peptidase S8 family.

1288484:G6R31 RS04640
gene id: 1288484:G6R31_RS04640
uniprot id: A0A6G7H288
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

1288484:G6R31 RS02335
gene id: 1288484:G6R31_RS02335
uniprot id: A0A6G7H1Q5
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1288484:G6R31 RS05735
gene id: 1288484:G6R31_RS05735
uniprot id: A0A6G7H2T1
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1288484:G6R31 RS06000
gene id: 1288484:G6R31_RS06000
uniprot id: A0A6G7H3R1
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Periplasm

1288484:G6R31 RS16005
gene id: 1288484:G6R31_RS16005
uniprot id: A0A6G7H8L0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1288484:G6R31 RS04430
gene id: 1288484:G6R31_RS04430
uniprot id: A0A6G7H6V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Set transporter family.
messages: Membrane

1288484:G6R31 RS06655
gene id: 1288484:G6R31_RS06655
uniprot id: A0A6G7H384
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1288484:G6R31 RS02420
gene id: 1288484:G6R31_RS02420
uniprot id: A0A6G7H733
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS07155
gene id: 1288484:G6R31_RS07155
uniprot id: A0A6G7H4L7
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1288484:G6R31 RS01990
gene id: 1288484:G6R31_RS01990
uniprot id: A0A6G7H0W2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1288484:G6R31 RS03795
gene id: 1288484:G6R31_RS03795
uniprot id: A0A6G7H252
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1288484:G6R31 RS12755
gene id: 1288484:G6R31_RS12755
uniprot id: A0A6G7H791
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1288484:G6R31 RS01545
gene id: 1288484:G6R31_RS01545
uniprot id: A0A6G7H0N9
names: Similarity
messages: Belongs to the peptidase S8 family.

1288484:G6R31 RS02870
gene id: 1288484:G6R31_RS02870
uniprot id: A0A6G7H2G2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1288484:G6R31 RS15390
gene id: 1288484:G6R31_RS15390
uniprot id: A0A6G7H892
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS03455
gene id: 1288484:G6R31_RS03455
uniprot id: A0A6G7H6X3
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS00650
gene id: 1288484:G6R31_RS00650
uniprot id: A0A6G7H0D0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1288484:G6R31 RS05740
gene id: 1288484:G6R31_RS05740
uniprot id: A0A6G7H3X6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1288484:G6R31 RS11185
gene id: 1288484:G6R31_RS11185
uniprot id: A0A6G7H6I8
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1288484:G6R31 RS02720
gene id: 1288484:G6R31_RS02720
uniprot id: A0A6G7H192
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1288484:G6R31 RS11330
gene id: 1288484:G6R31_RS11330
uniprot id: A0A6G7H5G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1288484:G6R31 RS11385
gene id: 1288484:G6R31_RS11385
uniprot id: A0A6G7H6B6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS07425
gene id: 1288484:G6R31_RS07425
uniprot id: A0A6G7H3Q2
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.

1288484:G6R31 RS08565
gene id: 1288484:G6R31_RS08565
uniprot id: A0A6G7H5A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1288484:G6R31 RS11585
gene id: 1288484:G6R31_RS11585
uniprot id: A0A6G7H5K1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1288484:G6R31 RS10130
gene id: 1288484:G6R31_RS10130
uniprot id: A0A6G7H5I4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1288484:G6R31 RS11565
gene id: 1288484:G6R31_RS11565
uniprot id: A0A6G7H6Q1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1288484:G6R31 RS01345
gene id: 1288484:G6R31_RS01345
uniprot id: A0A6G7H0K2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1288484:G6R31 RS08130
gene id: 1288484:G6R31_RS08130
uniprot id: A0A6G7H4A6
names: Similarity
messages: Belongs to the leucine-binding protein family.

1288484:G6R31 RS01310
gene id: 1288484:G6R31_RS01310
uniprot id: A0A6G7H165
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1288484:G6R31 RS06755
gene id: 1288484:G6R31_RS06755
uniprot id: A0A6G7H3Y0
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. Futalosine hydrolase subfamily.
messages: Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).

1288484:G6R31 RS02305
gene id: 1288484:G6R31_RS02305
uniprot id: A0A6G7H116
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1288484:G6R31 RS02670
gene id: 1288484:G6R31_RS02670
uniprot id: A0A6G7H183
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS02165
gene id: 1288484:G6R31_RS02165
uniprot id: A0A6G7H0Z0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1288484:G6R31 RS04510
gene id: 1288484:G6R31_RS04510
uniprot id: A0A6G7H2U6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1288484:G6R31 RS00780
gene id: 1288484:G6R31_RS00780
uniprot id: A0A6G7H159
names: Similarity
messages: Belongs to the peptidase S49 family.

1288484:G6R31 RS07140
gene id: 1288484:G6R31_RS07140
uniprot id: A0A6G7H422
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1288484:G6R31 RS16265
gene id: 1288484:G6R31_RS16265
uniprot id: A0A6G7H9H9
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS03915
gene id: 1288484:G6R31_RS03915
uniprot id: A0A6G7H1V5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1288484:G6R31 RS00035
gene id: 1288484:G6R31_RS00035
uniprot id: A0A6G7GZY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1288484:G6R31 RS13815
gene id: 1288484:G6R31_RS13815
uniprot id: A0A6G7H7D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1288484:G6R31 RS13460
gene id: 1288484:G6R31_RS13460
uniprot id: A0A6G7H6K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1288484:G6R31 RS14335
gene id: 1288484:G6R31_RS14335
uniprot id: A0A6G7H7Q2
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS09245
gene id: 1288484:G6R31_RS09245
uniprot id: A0A6G7H593
names: Similarity
messages: Belongs to the UPF0225 family.

1288484:G6R31 RS06450
gene id: 1288484:G6R31_RS06450
uniprot id: A0A6G7H3X8
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

1288484:G6R31 RS04635
gene id: 1288484:G6R31_RS04635
uniprot id: A0A6G7H2C4
names: Similarity
messages: Belongs to the aspartokinase family.

1288484:G6R31 RS03210
gene id: 1288484:G6R31_RS03210
uniprot id: A0A6G7H743
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Membrane

1288484:G6R31 RS10325
gene id: 1288484:G6R31_RS10325
uniprot id: A0A6G7H653
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1288484:G6R31 RS11140
gene id: 1288484:G6R31_RS11140
uniprot id: A0A6G7H5E7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1288484:G6R31 RS08285
gene id: 1288484:G6R31_RS08285
uniprot id: A0A6G7H4D5
names: Similarity
messages: Belongs to the citrate synthase family.

1288484:G6R31 RS08785
gene id: 1288484:G6R31_RS08785
uniprot id: A0A6G7H4V2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1288484:G6R31 RS06770
gene id: 1288484:G6R31_RS06770
uniprot id: A0A6G7H3D7
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS07355
gene id: 1288484:G6R31_RS07355
uniprot id: A0A6G7H4C3
names: Similarity
messages: Belongs to the thioredoxin family.

1288484:G6R31 RS03145
gene id: 1288484:G6R31_RS03145
uniprot id: A0A6G7H1G2
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1288484:G6R31 RS01690
gene id: 1288484:G6R31_RS01690
uniprot id: A0A6G7H6R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1288484:G6R31 RS10025
gene id: 1288484:G6R31_RS10025
uniprot id: A0A6G7H5G5
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1288484:G6R31 RS00850
gene id: 1288484:G6R31_RS00850
uniprot id: A0A6G7H0C1
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS07040
gene id: 1288484:G6R31_RS07040
uniprot id: A0A6G7H402
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1288484:G6R31 RS03330
gene id: 1288484:G6R31_RS03330
uniprot id: A0A6G7H2E4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1288484:G6R31 RS11400
gene id: 1288484:G6R31_RS11400
uniprot id: A0A6G7H5U7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1288484:G6R31 RS11005
gene id: 1288484:G6R31_RS11005
uniprot id: A0A6G7H5D3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS06035
gene id: 1288484:G6R31_RS06035
uniprot id: A0A6G7H316
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1288484:G6R31 RS05420
gene id: 1288484:G6R31_RS05420
uniprot id: A0A6G7H2Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1288484:G6R31 RS08170
gene id: 1288484:G6R31_RS08170
uniprot id: A0A6G7H4T0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1288484:G6R31 RS05465
gene id: 1288484:G6R31_RS05465
uniprot id: A0A6G7H3H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1288484:G6R31 RS12135
gene id: 1288484:G6R31_RS12135
uniprot id: A0A6G7H6Z1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1288484:G6R31 RS14850
gene id: 1288484:G6R31_RS14850
uniprot id: A0A6G7H924
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1288484:G6R31 RS14070
gene id: 1288484:G6R31_RS14070
uniprot id: A0A6G7H877
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1288484:G6R31 RS00915
gene id: 1288484:G6R31_RS00915
uniprot id: A0A6G7H0Q2
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1288484:G6R31 RS09535
gene id: 1288484:G6R31_RS09535
uniprot id: A0A6G7H5E0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1288484:G6R31 RS00050
gene id: 1288484:G6R31_RS00050
uniprot id: A0A6G7H0M3
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS02170
gene id: 1288484:G6R31_RS02170
uniprot id: A0A6G7H6T0
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

1288484:G6R31 RS13010
gene id: 1288484:G6R31_RS13010
uniprot id: A0A6G7H726
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1288484:G6R31 RS08965
gene id: 1288484:G6R31_RS08965
uniprot id: A0A6G7H5H4
names: Similarity
messages: Belongs to the SCO1/2 family.

1288484:G6R31 RS00345
gene id: 1288484:G6R31_RS00345
uniprot id: A0A6G7H0Q6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1288484:G6R31 RS09390
gene id: 1288484:G6R31_RS09390
uniprot id: A0A6G7H5P4
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

1288484:G6R31 RS11055
gene id: 1288484:G6R31_RS11055
uniprot id: A0A6G7H5G0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1288484:G6R31 RS11115
gene id: 1288484:G6R31_RS11115
uniprot id: A0A6G7H5Z5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1288484:G6R31 RS16020
gene id: 1288484:G6R31_RS16020
uniprot id: A0A6G7H8W3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1288484:G6R31 RS01825
gene id: 1288484:G6R31_RS01825
uniprot id: A0A6G7H153
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1288484:G6R31 RS13175
gene id: 1288484:G6R31_RS13175
uniprot id: A0A6G7H7G1
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1288484:G6R31 RS14750
gene id: 1288484:G6R31_RS14750
uniprot id: A0A6G7H7X2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1288484:G6R31 RS03110
gene id: 1288484:G6R31_RS03110
uniprot id: A0A6G7H1T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1288484:G6R31 RS07055
gene id: 1288484:G6R31_RS07055
uniprot id: A0A6G7H4J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1288484:G6R31 RS02570
gene id: 1288484:G6R31_RS02570
uniprot id: A0A6G7H1U5
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

1288484:G6R31 RS08395
gene id: 1288484:G6R31_RS08395
uniprot id: A0A6G7H575
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1288484:G6R31 RS15035
gene id: 1288484:G6R31_RS15035
uniprot id: A0A6G7H8W1
names: Similarity
messages: Belongs to the ParB family.

1288484:G6R31 RS10055
gene id: 1288484:G6R31_RS10055
uniprot id: A0A6G7H4U5
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1288484:G6R31 RS10240
gene id: 1288484:G6R31_RS10240
uniprot id: A0A6G7H5R2
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS07325
gene id: 1288484:G6R31_RS07325
uniprot id: A0A6G7H3J9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell inner membrane
messages: Cell membrane
messages: Forms a complex with MdtI.
messages: Membrane

1288484:G6R31 RS01070
gene id: 1288484:G6R31_RS01070
uniprot id: A0A6G7H171
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

1288484:G6R31 RS03550
gene id: 1288484:G6R31_RS03550
uniprot id: A0A6G7H2T4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS04645
gene id: 1288484:G6R31_RS04645
uniprot id: A0A6G7H3D0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1288484:G6R31 RS08765
gene id: 1288484:G6R31_RS08765
uniprot id: A0A6G7H7R1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1288484:G6R31 RS10485
gene id: 1288484:G6R31_RS10485
uniprot id: A0A6G7H538
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1288484:G6R31 RS09815
gene id: 1288484:G6R31_RS09815
uniprot id: A0A6G7H5K8
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

1288484:G6R31 RS10430
gene id: 1288484:G6R31_RS10430
uniprot id: A0A6G7H5S2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1288484:G6R31 RS12860
gene id: 1288484:G6R31_RS12860
uniprot id: A0A6G7H6T1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1288484:G6R31 RS15105
gene id: 1288484:G6R31_RS15105
uniprot id: A0A6G7H8U5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1288484:G6R31 RS08375
gene id: 1288484:G6R31_RS08375
uniprot id: A0A6G7H4N2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1288484:G6R31 RS02400
gene id: 1288484:G6R31_RS02400
uniprot id: A0A6G7H1R6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1288484:G6R31 RS13160
gene id: 1288484:G6R31_RS13160
uniprot id: A0A6G7H6Y0
names: Similarity
messages: Belongs to the Fur family.

1288484:G6R31 RS10065
gene id: 1288484:G6R31_RS10065
uniprot id: A0A6G7H580
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1288484:G6R31 RS06080
gene id: 1288484:G6R31_RS06080
uniprot id: A0A6G7H3A5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1288484:G6R31 RS00680
gene id: 1288484:G6R31_RS00680
uniprot id: A0A6G7H091
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS09345
gene id: 1288484:G6R31_RS09345
uniprot id: A0A6G7H4W3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS14080
gene id: 1288484:G6R31_RS14080
uniprot id: A0A6G7H7M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1288484:G6R31 RS10940
gene id: 1288484:G6R31_RS10940
uniprot id: A0A6G7H5E2
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1288484:G6R31 RS03240
gene id: 1288484:G6R31_RS03240
uniprot id: A0A6G7H1V2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1288484:G6R31 RS15135
gene id: 1288484:G6R31_RS15135
uniprot id: A0A6G7H8I7
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1288484:G6R31 RS09215
gene id: 1288484:G6R31_RS09215
uniprot id: A0A6G7H4H5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

1288484:G6R31 RS02160
gene id: 1288484:G6R31_RS02160
uniprot id: A0A6G7H1T9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1288484:G6R31 RS10775
gene id: 1288484:G6R31_RS10775
uniprot id: A0A6G7H594
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1288484:G6R31 RS14985
gene id: 1288484:G6R31_RS14985
uniprot id: A0A6G7H8B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0316 family.
messages: Cell membrane
messages: Membrane

1288484:G6R31 RS06425
gene id: 1288484:G6R31_RS06425
uniprot id: A0A6G7H377
names: Similarity
messages: Belongs to the ycf81 family.

1288484:G6R31 RS01030
gene id: 1288484:G6R31_RS01030
uniprot id: A0A6G7H0I9
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1288484:G6R31 RS02180
gene id: 1288484:G6R31_RS02180
uniprot id: A0A6G7H1M6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1288484:G6R31 RS03090
gene id: 1288484:G6R31_RS03090
uniprot id: A0A6G7H1G0
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS08145
gene id: 1288484:G6R31_RS08145
uniprot id: A0A6G7H4J2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1288484:G6R31 RS12270
gene id: 1288484:G6R31_RS12270
uniprot id: A0A6G7H6Q8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1288484:G6R31 RS12910
gene id: 1288484:G6R31_RS12910
uniprot id: A0A6G7H6X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1288484:G6R31 RS00150
gene id: 1288484:G6R31_RS00150
uniprot id: A0A6G7H0U9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1288484:G6R31 RS12350
gene id: 1288484:G6R31_RS12350
uniprot id: A0A6G7H6K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1288484:G6R31 RS08045
gene id: 1288484:G6R31_RS08045
uniprot id: A0A6G7H3X9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1288484:G6R31 RS14330
gene id: 1288484:G6R31_RS14330
uniprot id: A0A6G7H8T6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

1288484:G6R31 RS01605
gene id: 1288484:G6R31_RS01605
uniprot id: A0A6G7H0T8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1288484:G6R31 RS14325
gene id: 1288484:G6R31_RS14325
uniprot id: A0A6G7H7R3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS11590
gene id: 1288484:G6R31_RS11590
uniprot id: A0A6G7H5X8
names: Similarity
messages: Belongs to the pyruvate kinase family.

1288484:G6R31 RS03425
gene id: 1288484:G6R31_RS03425
uniprot id: A0A6G7H2R4
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1288484:G6R31 RS08260
gene id: 1288484:G6R31_RS08260
uniprot id: A0A6G7H419
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1288484:G6R31 RS10435
gene id: 1288484:G6R31_RS10435
uniprot id: A0A6G7H5U0
names: Similarity
messages: Belongs to the peptidase M29 family.

1288484:G6R31 RS13180
gene id: 1288484:G6R31_RS13180
uniprot id: A0A6G7H6C8
names: Similarity
messages: Belongs to the CinA family.

1288484:G6R31 RS08360
gene id: 1288484:G6R31_RS08360
uniprot id: A0A6G7H4R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1288484:G6R31 RS16675
gene id: 1288484:G6R31_RS16675
uniprot id: A0A6G7H902
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1288484:G6R31 RS12620
gene id: 1288484:G6R31_RS12620
uniprot id: A0A6G7H8H4
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS04470
gene id: 1288484:G6R31_RS04470
uniprot id: A0A6G7H6T4
names: Similarity
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1288484:G6R31 RS05440
gene id: 1288484:G6R31_RS05440
uniprot id: A0A6G7H2R9
names: Similarity
messages: Belongs to the GARS family.

1288484:G6R31 RS03435
gene id: 1288484:G6R31_RS03435
uniprot id: A0A6G7H2G4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 15 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1288484:G6R31 RS05355
gene id: 1288484:G6R31_RS05355
uniprot id: A0A6G7H3A0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1288484:G6R31 RS02120
gene id: 1288484:G6R31_RS02120
uniprot id: A0A6G7H1A2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1288484:G6R31 RS12565
gene id: 1288484:G6R31_RS12565
uniprot id: A0A6G7H6E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1288484:G6R31 RS09835
gene id: 1288484:G6R31_RS09835
uniprot id: A0A6G7H5J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1288484:G6R31 RS06550
gene id: 1288484:G6R31_RS06550
uniprot id: A0A6G7H4A8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

1288484:G6R31 RS05750
gene id: 1288484:G6R31_RS05750
uniprot id: A0A6G7H3M1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

1288484:G6R31 RS04535
gene id: 1288484:G6R31_RS04535
uniprot id: A0A6G7H3B1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1288484:G6R31 RS14955
gene id: 1288484:G6R31_RS14955
uniprot id: A0A6G7H848
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1288484:G6R31 RS04525
gene id: 1288484:G6R31_RS04525
uniprot id: A0A6G7H2A4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1288484:G6R31 RS06470
gene id: 1288484:G6R31_RS06470
uniprot id: A0A6G7H3W5
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1288484:G6R31 RS03380
gene id: 1288484:G6R31_RS03380
uniprot id: A0A6G7H1L1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1288484:G6R31 RS07630
gene id: 1288484:G6R31_RS07630
uniprot id: A0A6G7H725
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1288484:G6R31 RS00440
gene id: 1288484:G6R31_RS00440
uniprot id: A0A6G7H186
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS12575
gene id: 1288484:G6R31_RS12575
uniprot id: A0A6G7H855
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1288484:G6R31 RS07430
gene id: 1288484:G6R31_RS07430
uniprot id: A0A6G7H3M6
names: Similarity
messages: Belongs to the acylphosphatase family.

1288484:G6R31 RS16060
gene id: 1288484:G6R31_RS16060
uniprot id: A0A6G7H9F0
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS06360
gene id: 1288484:G6R31_RS06360
uniprot id: A0A6G7H3N2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS03800
gene id: 1288484:G6R31_RS03800
uniprot id: A0A6G7H2G9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1288484:G6R31 RS08550
gene id: 1288484:G6R31_RS08550
uniprot id: A0A6G7H4R2
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS01855
gene id: 1288484:G6R31_RS01855
uniprot id: A0A6G7H0T6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1288484:G6R31 RS08530
gene id: 1288484:G6R31_RS08530
uniprot id: A0A6G7H442
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

1288484:G6R31 RS12480
gene id: 1288484:G6R31_RS12480
uniprot id: A0A6G7H644
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1288484:G6R31 RS09370
gene id: 1288484:G6R31_RS09370
uniprot id: A0A6G7H552
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1288484:G6R31 RS00380
gene id: 1288484:G6R31_RS00380
uniprot id: A0A6G7H176
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1288484:G6R31 RS13090
gene id: 1288484:G6R31_RS13090
uniprot id: A0A6G7H7Q9
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1288484:G6R31 RS03310
gene id: 1288484:G6R31_RS03310
uniprot id: A0A6G7H1N6
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1288484:G6R31 RS15385
gene id: 1288484:G6R31_RS15385
uniprot id: A0A6G7H949
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1288484:G6R31 RS08190
gene id: 1288484:G6R31_RS08190
uniprot id: A0A6G7H4N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane

1288484:G6R31 RS11580
gene id: 1288484:G6R31_RS11580
uniprot id: A0A6G7H6E9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1288484:G6R31 RS11620
gene id: 1288484:G6R31_RS11620
uniprot id: A0A6G7H6Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1288484:G6R31 RS07675
gene id: 1288484:G6R31_RS07675
uniprot id: A0A6G7H4V6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1288484:G6R31 RS07085
gene id: 1288484:G6R31_RS07085
uniprot id: A0A6G7H476
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1288484:G6R31 RS08450
gene id: 1288484:G6R31_RS08450
uniprot id: A0A6G7H450
names: Similarity
messages: Belongs to the peptidase M17 family.

1288484:G6R31 RS15250
gene id: 1288484:G6R31_RS15250
uniprot id: A0A6G7H899
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

1288484:G6R31 RS02580
gene id: 1288484:G6R31_RS02580
uniprot id: A0A6G7H1S9
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1288484:G6R31 RS00210
gene id: 1288484:G6R31_RS00210
uniprot id: A0A6G7H0V9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1288484:G6R31 RS10495
gene id: 1288484:G6R31_RS10495
uniprot id: A0A6G7H519
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1288484:G6R31 RS04680
gene id: 1288484:G6R31_RS04680
uniprot id: A0A6G7H315
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1288484:G6R31 RS13540
gene id: 1288484:G6R31_RS13540
uniprot id: A0A6G7H6I6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1288484:G6R31 RS08220
gene id: 1288484:G6R31_RS08220
uniprot id: A0A6G7H404
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1288484:G6R31 RS12655
gene id: 1288484:G6R31_RS12655
uniprot id: A0A6G7H6T7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1288484:G6R31 RS13650
gene id: 1288484:G6R31_RS13650
uniprot id: A0A6G7H760
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1288484:G6R31 RS09850
gene id: 1288484:G6R31_RS09850
uniprot id: A0A6G7H4U1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1288484:G6R31 RS04610
gene id: 1288484:G6R31_RS04610
uniprot id: A0A6G7H283
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1288484:G6R31 RS15940
gene id: 1288484:G6R31_RS15940
uniprot id: A0A6G7H8K7
names: Similarity
messages: Belongs to the transposase 7 family.

1288484:G6R31 RS10760
gene id: 1288484:G6R31_RS10760
uniprot id: A0A6G7H5Y9
names: Similarity
messages: Belongs to the DprA/Smf family.

1288484:G6R31 RS06820
gene id: 1288484:G6R31_RS06820
uniprot id: A0A6G7H425
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS05935
gene id: 1288484:G6R31_RS05935
uniprot id: A0A6G7H6W3
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily.

1288484:G6R31 RS05485
gene id: 1288484:G6R31_RS05485
uniprot id: A0A6G7H3C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1288484:G6R31 RS07115
gene id: 1288484:G6R31_RS07115
uniprot id: A0A6G7H498
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1288484:G6R31 RS03105
gene id: 1288484:G6R31_RS03105
uniprot id: A0A6G7H1G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1288484:G6R31 RS02315
gene id: 1288484:G6R31_RS02315
uniprot id: A0A6G7H123
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1288484:G6R31 RS00640
gene id: 1288484:G6R31_RS00640
uniprot id: A0A6G7H101
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1288484:G6R31 RS07170
gene id: 1288484:G6R31_RS07170
uniprot id: A0A6G7H3H0
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1288484:G6R31 RS13240
gene id: 1288484:G6R31_RS13240
uniprot id: A0A6G7H765
names: Similarity
messages: Belongs to the peptidase S8 family.

1288484:G6R31 RS14935
gene id: 1288484:G6R31_RS14935
uniprot id: A0A6G7H8A8
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

1288484:G6R31 RS16740
gene id: 1288484:G6R31_RS16740
uniprot id: A0A6G7H9U0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1288484:G6R31 RS12395
gene id: 1288484:G6R31_RS12395
uniprot id: A0A6G7H6P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1288484:G6R31 RS02025
gene id: 1288484:G6R31_RS02025
uniprot id: A0A6G7H1I0
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1288484:G6R31 RS02940
gene id: 1288484:G6R31_RS02940
uniprot id: A0A6G7H1Q3
names: Similarity
messages: Belongs to the FemABX family.

1288484:G6R31 RS08800
gene id: 1288484:G6R31_RS08800
uniprot id: A0A6G7H5E4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS11065
gene id: 1288484:G6R31_RS11065
uniprot id: A0A6G7H6G9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1288484:G6R31 RS01515
gene id: 1288484:G6R31_RS01515
uniprot id: A0A6G7H103
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1288484:G6R31 RS11780
gene id: 1288484:G6R31_RS11780
uniprot id: A0A6G7H6A8
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS07190
gene id: 1288484:G6R31_RS07190
uniprot id: A0A6G7H494
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS06310
gene id: 1288484:G6R31_RS06310
uniprot id: A0A6G7H319
names: Similarity
messages: Belongs to the RutC family.

1288484:G6R31 RS09290
gene id: 1288484:G6R31_RS09290
uniprot id: A0A6G7H4V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

1288484:G6R31 RS01530
gene id: 1288484:G6R31_RS01530
uniprot id: A0A6G7H1A4
names: Similarity
messages: Belongs to the GSP E family.

1288484:G6R31 RS08910
gene id: 1288484:G6R31_RS08910
uniprot id: A0A6G7H4D1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1288484:G6R31 RS10790
gene id: 1288484:G6R31_RS10790
uniprot id: A0A6G7H588
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS07460
gene id: 1288484:G6R31_RS07460
uniprot id: A0A6G7H3Z7
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1288484:G6R31 RS11610
gene id: 1288484:G6R31_RS11610
uniprot id: A0A6G7H5Q2
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1288484:G6R31 RS02345
gene id: 1288484:G6R31_RS02345
uniprot id: A0A6G7H1U7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS00410
gene id: 1288484:G6R31_RS00410
uniprot id: A0A6G7H0G3
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS11650
gene id: 1288484:G6R31_RS11650
uniprot id: A0A6G7H6D6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1288484:G6R31 RS14635
gene id: 1288484:G6R31_RS14635
uniprot id: A0A6G7H858
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1288484:G6R31 RS14145
gene id: 1288484:G6R31_RS14145
uniprot id: A0A6G7H8G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1288484:G6R31 RS09280
gene id: 1288484:G6R31_RS09280
uniprot id: A0A6G7H5C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1288484:G6R31 RS04410
gene id: 1288484:G6R31_RS04410
uniprot id: A0A6G7H244
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1288484:G6R31 RS16170
gene id: 1288484:G6R31_RS16170
uniprot id: A0A6G7H9S5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Cell membrane
messages: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
messages: Membrane

1288484:G6R31 RS12425
gene id: 1288484:G6R31_RS12425
uniprot id: A0A6G7H742
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1288484:G6R31 RS02100
gene id: 1288484:G6R31_RS02100
uniprot id: A0A6G7H0Y3
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS03005
gene id: 1288484:G6R31_RS03005
uniprot id: A0A6G7H6T3
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

1288484:G6R31 RS01355
gene id: 1288484:G6R31_RS01355
uniprot id: A0A6G7H185
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS08820
gene id: 1288484:G6R31_RS08820
uniprot id: A0A6G7H490
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1288484:G6R31 RS07395
gene id: 1288484:G6R31_RS07395
uniprot id: A0A6G7H3K8
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1288484:G6R31 RS02000
gene id: 1288484:G6R31_RS02000
uniprot id: A0A6G7H0V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

1288484:G6R31 RS12580
gene id: 1288484:G6R31_RS12580
uniprot id: A0A6G7H6S7
names: Similarity
messages: Belongs to the DinB family.

1288484:G6R31 RS05785
gene id: 1288484:G6R31_RS05785
uniprot id: A0A6G7H2X6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1288484:G6R31 RS14455
gene id: 1288484:G6R31_RS14455
uniprot id: A0A6G7H8L1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

1288484:G6R31 RS11955
gene id: 1288484:G6R31_RS11955
uniprot id: A0A6G7H6L0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1288484:G6R31 RS02450
gene id: 1288484:G6R31_RS02450
uniprot id: A0A6G7H1G3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS01695
gene id: 1288484:G6R31_RS01695
uniprot id: A0A6G7H0R0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS06845
gene id: 1288484:G6R31_RS06845
uniprot id: A0A6G7H3A8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

1288484:G6R31 RS14375
gene id: 1288484:G6R31_RS14375
uniprot id: A0A6G7H8C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

1288484:G6R31 RS10105
gene id: 1288484:G6R31_RS10105
uniprot id: A0A6G7H5Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1288484:G6R31 RS16125
gene id: 1288484:G6R31_RS16125
uniprot id: A0A6G7H8K9
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

1288484:G6R31 RS14405
gene id: 1288484:G6R31_RS14405
uniprot id: A0A6G7H8K0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1288484:G6R31 RS07480
gene id: 1288484:G6R31_RS07480
uniprot id: A0A6G7H486
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1288484:G6R31 RS01335
gene id: 1288484:G6R31_RS01335
uniprot id: A0A6G7H0K6
names: Similarity
messages: Belongs to the catalase family.

1288484:G6R31 RS01400
gene id: 1288484:G6R31_RS01400
uniprot id: A0A6G7H1F8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1288484:G6R31 RS10405
gene id: 1288484:G6R31_RS10405
uniprot id: A0A6G7H528
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1288484:G6R31 RS10095
gene id: 1288484:G6R31_RS10095
uniprot id: A0A6G7H613
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1288484:G6R31 RS14675
gene id: 1288484:G6R31_RS14675
uniprot id: A0A6G7H7W2
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1288484:G6R31 RS00425
gene id: 1288484:G6R31_RS00425
uniprot id: A0A6G7H0R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1288484:G6R31 RS13235
gene id: 1288484:G6R31_RS13235
uniprot id: A0A6G7H823
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS06505
gene id: 1288484:G6R31_RS06505
uniprot id: A0A6G7H7B4
names: Similarity
messages: Belongs to the peptidase S1B family.

1288484:G6R31 RS01445
gene id: 1288484:G6R31_RS01445
uniprot id: A0A6G7H1Q8
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS15295
gene id: 1288484:G6R31_RS15295
uniprot id: A0A6G7H8X0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1288484:G6R31 RS16360
gene id: 1288484:G6R31_RS16360
uniprot id: A0A6G7H9E8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1288484:G6R31 RS09995
gene id: 1288484:G6R31_RS09995
uniprot id: A0A6G7H5N7
names: Similarity
messages: Belongs to the UbiD family.

1288484:G6R31 RS00805
gene id: 1288484:G6R31_RS00805
uniprot id: A0A6G7H0Z8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

1288484:G6R31 RS11930
gene id: 1288484:G6R31_RS11930
uniprot id: A0A6G7H6W1
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1288484:G6R31 RS13355
gene id: 1288484:G6R31_RS13355
uniprot id: A0A6G7H7J1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1288484:G6R31 RS12715
gene id: 1288484:G6R31_RS12715
uniprot id: A0A6G7H632
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1288484:G6R31 RS00645
gene id: 1288484:G6R31_RS00645
uniprot id: A0A6G7H0V5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1288484:G6R31 RS01810
gene id: 1288484:G6R31_RS01810
uniprot id: A0A6G7H0S9
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

1288484:G6R31 RS15340
gene id: 1288484:G6R31_RS15340
uniprot id: A0A6G7H931
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1288484:G6R31 RS09400
gene id: 1288484:G6R31_RS09400
uniprot id: A0A6G7H5D7
names: Similarity
messages: Belongs to the glutamine synthetase family.

1288484:G6R31 RS10945
gene id: 1288484:G6R31_RS10945
uniprot id: A0A6G7H5C3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1288484:G6R31 RS01795
gene id: 1288484:G6R31_RS01795
uniprot id: A0A6G7H0W8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1288484:G6R31 RS00285
gene id: 1288484:G6R31_RS00285
uniprot id: A0A6G7H0P6
names: Similarity
messages: Belongs to the peptidase M29 family.

1288484:G6R31 RS05805
gene id: 1288484:G6R31_RS05805
uniprot id: A0A6G7H3N1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1288484:G6R31 RS11735
gene id: 1288484:G6R31_RS11735
uniprot id: A0A6G7H5S0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1288484:G6R31 RS12355
gene id: 1288484:G6R31_RS12355
uniprot id: A0A6G7H624
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1288484:G6R31 RS12245
gene id: 1288484:G6R31_RS12245
uniprot id: A0A6G7H603
names: Similarity
messages: Belongs to the peptidase M16 family.

1288484:G6R31 RS02070
gene id: 1288484:G6R31_RS02070
uniprot id: A0A6G7H1K6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1288484:G6R31 RS02210
gene id: 1288484:G6R31_RS02210
uniprot id: A0A6G7H102
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1288484:G6R31 RS08675
gene id: 1288484:G6R31_RS08675
uniprot id: A0A6G7H483
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

1288484:G6R31 RS05730
gene id: 1288484:G6R31_RS05730
uniprot id: A0A6G7H2W7
names: Similarity
messages: Belongs to the MoaB/Mog family.

1288484:G6R31 RS14900
gene id: 1288484:G6R31_RS14900
uniprot id: A0A6G7H807
names: Similarity
messages: Belongs to the threonine synthase family.

1288484:G6R31 RS14140
gene id: 1288484:G6R31_RS14140
uniprot id: A0A6G7H8Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1288484:G6R31 RS02905
gene id: 1288484:G6R31_RS02905
uniprot id: A0A6G7H1Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1288484:G6R31 RS13135
gene id: 1288484:G6R31_RS13135
uniprot id: A0A6G7H696
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1288484:G6R31 RS08915
gene id: 1288484:G6R31_RS08915
uniprot id: A0A6G7H5G4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1288484:G6R31 RS13895
gene id: 1288484:G6R31_RS13895
uniprot id: A0A6G7H893
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1288484:G6R31 RS10460
gene id: 1288484:G6R31_RS10460
uniprot id: A0A6G7H540
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1288484:G6R31 RS07450
gene id: 1288484:G6R31_RS07450
uniprot id: A0A6G7H4F8
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS09630
gene id: 1288484:G6R31_RS09630
uniprot id: A0A6G7H4P5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1288484:G6R31 RS07965
gene id: 1288484:G6R31_RS07965
uniprot id: A0A6G7H4J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1288484:G6R31 RS10425
gene id: 1288484:G6R31_RS10425
uniprot id: A0A6G7H5D9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1288484:G6R31 RS06490
gene id: 1288484:G6R31_RS06490
uniprot id: A0A6G7H495
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1288484:G6R31 RS06410
gene id: 1288484:G6R31_RS06410
uniprot id: A0A6G7H3V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

1288484:G6R31 RS11515
gene id: 1288484:G6R31_RS11515
uniprot id: A0A6G7H6D9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1288484:G6R31 RS14835
gene id: 1288484:G6R31_RS14835
uniprot id: A0A6G7H8L2
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1288484:G6R31 RS05630
gene id: 1288484:G6R31_RS05630
uniprot id: A0A6G7H2Q7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1288484:G6R31 RS07975
gene id: 1288484:G6R31_RS07975
uniprot id: A0A6G7H4G2
names: Cofactor
messages: Binds 1 FAD per subunit.

1288484:G6R31 RS07380
gene id: 1288484:G6R31_RS07380
uniprot id: A0A6G7H4Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1288484:G6R31 RS06465
gene id: 1288484:G6R31_RS06465
uniprot id: A0A6G7H3T0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS02685
gene id: 1288484:G6R31_RS02685
uniprot id: A0A6G7H1K4
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS12975
gene id: 1288484:G6R31_RS12975
uniprot id: A0A6G7H6Y8
names: Similarity
messages: Belongs to the GreA/GreB family.

1288484:G6R31 RS02530
gene id: 1288484:G6R31_RS02530
uniprot id: A0A6G7H1R9
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS11860
gene id: 1288484:G6R31_RS11860
uniprot id: A0A6G7H6V1
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS05345
gene id: 1288484:G6R31_RS05345
uniprot id: A0A6G7H2L1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20A family. LysK subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine.
messages: Cytoplasm

1288484:G6R31 RS10200
gene id: 1288484:G6R31_RS10200
uniprot id: A0A6G7H517
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS08545
gene id: 1288484:G6R31_RS08545
uniprot id: A0A6G7H4X3
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1288484:G6R31 RS12905
gene id: 1288484:G6R31_RS12905
uniprot id: A0A6G7H7G5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1288484:G6R31 RS10600
gene id: 1288484:G6R31_RS10600
uniprot id: A0A6G7H692
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1288484:G6R31 RS07185
gene id: 1288484:G6R31_RS07185
uniprot id: A0A6G7H463
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1288484:G6R31 RS09135
gene id: 1288484:G6R31_RS09135
uniprot id: A0A6G7H4H1
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1288484:G6R31 RS07910
gene id: 1288484:G6R31_RS07910
uniprot id: A0A6G7H467
names: Cofactor
messages: Can also use Mn(2+) ion.

1288484:G6R31 RS00675
gene id: 1288484:G6R31_RS00675
uniprot id: A0A6G7H139
names: Similarity
messages: Belongs to the leucine-binding protein family.

1288484:G6R31 RS09085
gene id: 1288484:G6R31_RS09085
uniprot id: A0A6G7H5J5
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1288484:G6R31 RS07035
gene id: 1288484:G6R31_RS07035
uniprot id: A0A6G7H466
names: Similarity
messages: Belongs to the ribF family.

1288484:G6R31 RS05615
gene id: 1288484:G6R31_RS05615
uniprot id: A0A6G7H2U7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1288484:G6R31 RS12705
gene id: 1288484:G6R31_RS12705
uniprot id: A0A6G7H647
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1288484:G6R31 RS12605
gene id: 1288484:G6R31_RS12605
uniprot id: A0A6G7H7H5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1288484:G6R31 RS02935
gene id: 1288484:G6R31_RS02935
uniprot id: A0A6G7H1D2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1288484:G6R31 RS06315
gene id: 1288484:G6R31_RS06315
uniprot id: A0A6G7H3V8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1288484:G6R31 RS04515
gene id: 1288484:G6R31_RS04515
uniprot id: A0A6G7H2Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1288484:G6R31 RS05910
gene id: 1288484:G6R31_RS05910
uniprot id: A0A6G7H2W1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1288484:G6R31 RS02830
gene id: 1288484:G6R31_RS02830
uniprot id: A0A6G7H1B0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1288484:G6R31 RS14580
gene id: 1288484:G6R31_RS14580
uniprot id: A0A6G7H8H2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1288484:G6R31 RS00550
gene id: 1288484:G6R31_RS00550
uniprot id: A0A6G7H070
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Membrane

1288484:G6R31 RS14410
gene id: 1288484:G6R31_RS14410
uniprot id: A0A6G7H7P2
names: Similarity
messages: Belongs to the PstS family.

1288484:G6R31 RS02250
gene id: 1288484:G6R31_RS02250
uniprot id: A0A6G7H107
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1288484:G6R31 RS11815
gene id: 1288484:G6R31_RS11815
uniprot id: A0A6G7H792
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1288484:G6R31 RS03805
gene id: 1288484:G6R31_RS03805
uniprot id: A0A6G7H2K6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

1288484:G6R31 RS04005
gene id: 1288484:G6R31_RS04005
uniprot id: A0A6G7H313
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1288484:G6R31 RS03320
gene id: 1288484:G6R31_RS03320
uniprot id: A0A6G7H2P3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1288484:G6R31 RS09460
gene id: 1288484:G6R31_RS09460
uniprot id: A0A6G7H4K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1288484:G6R31 RS14120
gene id: 1288484:G6R31_RS14120
uniprot id: A0A6G7H839
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

1288484:G6R31 RS02805
gene id: 1288484:G6R31_RS02805
uniprot id: A0A6G7H1E9
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1288484:G6R31 RS11350
gene id: 1288484:G6R31_RS11350
uniprot id: A0A6G7H635
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

1288484:G6R31 RS08400
gene id: 1288484:G6R31_RS08400
uniprot id: A0A6G7H433
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1288484:G6R31 RS14790
gene id: 1288484:G6R31_RS14790
uniprot id: A0A6G7H7Y8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1288484:G6R31 RS02665
gene id: 1288484:G6R31_RS02665
uniprot id: A0A6G7H2C3
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1288484:G6R31 RS16110
gene id: 1288484:G6R31_RS16110
uniprot id: A0A6G7H8N0
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

1288484:G6R31 RS09540
gene id: 1288484:G6R31_RS09540
uniprot id: A0A6G7H582
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1288484:G6R31 RS10345
gene id: 1288484:G6R31_RS10345
uniprot id: A0A6G7H5D0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1288484:G6R31 RS09640
gene id: 1288484:G6R31_RS09640
uniprot id: A0A6G7H4N0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1288484:G6R31 RS03400
gene id: 1288484:G6R31_RS03400
uniprot id: A0A6G7H299
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1288484:G6R31 RS02300
gene id: 1288484:G6R31_RS02300
uniprot id: A0A6G7H155
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1288484:G6R31 RS10205
gene id: 1288484:G6R31_RS10205
uniprot id: A0A6G7H501
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1288484:G6R31 RS15075
gene id: 1288484:G6R31_RS15075
uniprot id: A0A6G7H968
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1288484:G6R31 RS02705
gene id: 1288484:G6R31_RS02705
uniprot id: A0A6G7H1C9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA.

1288484:G6R31 RS03345
gene id: 1288484:G6R31_RS03345
uniprot id: A0A6G7H289
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Dimer of large and small chains.

1288484:G6R31 RS10970
gene id: 1288484:G6R31_RS10970
uniprot id: A0A6G7H5M7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1288484:G6R31 RS10070
gene id: 1288484:G6R31_RS10070
uniprot id: A0A6G7H5K7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1288484:G6R31 RS03390
gene id: 1288484:G6R31_RS03390
uniprot id: A0A6G7H1L3
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS08770
gene id: 1288484:G6R31_RS08770
uniprot id: A0A6G7H4L5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS14050
gene id: 1288484:G6R31_RS14050
uniprot id: A0A6G7H7H8
names: Similarity
messages: Belongs to the CdaR family.

1288484:G6R31 RS07025
gene id: 1288484:G6R31_RS07025
uniprot id: A0A6G7H3R8
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

1288484:G6R31 RS15210
gene id: 1288484:G6R31_RS15210
uniprot id: A0A6G7H8F5
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

1288484:G6R31 RS02110
gene id: 1288484:G6R31_RS02110
uniprot id: A0A6G7H0X6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1288484:G6R31 RS12000
gene id: 1288484:G6R31_RS12000
uniprot id: A0A6G7H6E1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1288484:G6R31 RS07365
gene id: 1288484:G6R31_RS07365
uniprot id: A0A6G7H460
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1288484:G6R31 RS10075
gene id: 1288484:G6R31_RS10075
uniprot id: A0A6G7H5N0
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1288484:G6R31 RS07130
gene id: 1288484:G6R31_RS07130
uniprot id: A0A6G7H453
names: Similarity
messages: Belongs to the Skp family.

1288484:G6R31 RS09515
gene id: 1288484:G6R31_RS09515
uniprot id: A0A6G7H4K9
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1288484:G6R31 RS03285
gene id: 1288484:G6R31_RS03285
uniprot id: A0A6G7H1J4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1288484:G6R31 RS06580
gene id: 1288484:G6R31_RS06580
uniprot id: A0A6G7H3Y4
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX21/DDX50 subfamily.

1288484:G6R31 RS00665
gene id: 1288484:G6R31_RS00665
uniprot id: A0A6G7H0A0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1288484:G6R31 RS15060
gene id: 1288484:G6R31_RS15060
uniprot id: A0A6G7H8Q1
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1288484:G6R31 RS00670
gene id: 1288484:G6R31_RS00670
uniprot id: A0A6G7H7S8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1288484:G6R31 RS01035
gene id: 1288484:G6R31_RS01035
uniprot id: A0A6G7H0F1
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1288484:G6R31 RS03775
gene id: 1288484:G6R31_RS03775
uniprot id: A0A6G7H2X4
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

1288484:G6R31 RS11010
gene id: 1288484:G6R31_RS11010
uniprot id: A0A6G7H6F9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS05340
gene id: 1288484:G6R31_RS05340
uniprot id: A0A6G7H3F2
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS02285
gene id: 1288484:G6R31_RS02285
uniprot id: A0A6G7H1P5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1288484:G6R31 RS04425
gene id: 1288484:G6R31_RS04425
uniprot id: A0A6G7H2Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1288484:G6R31 RS15080
gene id: 1288484:G6R31_RS15080
uniprot id: A0A6G7H832
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1288484:G6R31 RS13045
gene id: 1288484:G6R31_RS13045
uniprot id: A0A6G7H6D4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS16820
gene id: 1288484:G6R31_RS16820
uniprot id: A0A6G7H1X8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1288484:G6R31 RS03295
gene id: 1288484:G6R31_RS03295
uniprot id: A0A6G7H279
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1288484:G6R31 RS00825
gene id: 1288484:G6R31_RS00825
uniprot id: A0A6G7H0C2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1288484:G6R31 RS12200
gene id: 1288484:G6R31_RS12200
uniprot id: A0A6G7H5W7
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1288484:G6R31 RS10395
gene id: 1288484:G6R31_RS10395
uniprot id: A0A6G7H529
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1288484:G6R31 RS01885
gene id: 1288484:G6R31_RS01885
uniprot id: A0A6G7H0T7
names: Similarity
messages: Belongs to the SCO1/2 family.

1288484:G6R31 RS11240
gene id: 1288484:G6R31_RS11240
uniprot id: A0A6G7H6J8
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.

1288484:G6R31 RS07890
gene id: 1288484:G6R31_RS07890
uniprot id: A0A6G7H4M8
names: Similarity
messages: Belongs to the histone deacetylase family.

1288484:G6R31 RS08605
gene id: 1288484:G6R31_RS08605
uniprot id: A0A6G7H499
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1288484:G6R31 RS14460
gene id: 1288484:G6R31_RS14460
uniprot id: A0A6G7H7Q1
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

1288484:G6R31 RS14400
gene id: 1288484:G6R31_RS14400
uniprot id: A0A6G7H7R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

1288484:G6R31 RS11855
gene id: 1288484:G6R31_RS11855
uniprot id: A0A6G7H5S1
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the NOS family. Bacterial NOS oxygenase subfamily.
messages: Catalyzes the production of nitric oxide.
messages: Homodimer.
messages: This protein is similar to the oxygenase domain of eukaryotic nitric oxide synthases but lacks the reductase domain which, in eukaryotes, is responsible for transfer of electrons to the ferric heme during nitric oxide synthesis.

1288484:G6R31 RS14255
gene id: 1288484:G6R31_RS14255
uniprot id: A0A6G7H7Q3
names: Similarity
messages: Belongs to the cytochrome P450 family.

1288484:G6R31 RS04440
gene id: 1288484:G6R31_RS04440
uniprot id: A0A6G7H2H3
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS06955
gene id: 1288484:G6R31_RS06955
uniprot id: A0A6G7H468
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1288484:G6R31 RS13200
gene id: 1288484:G6R31_RS13200
uniprot id: A0A6G7H728
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1288484:G6R31 RS12855
gene id: 1288484:G6R31_RS12855
uniprot id: A0A6G7H6Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1288484:G6R31 RS06855
gene id: 1288484:G6R31_RS06855
uniprot id: A0A6G7H3A9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1288484:G6R31 RS08840
gene id: 1288484:G6R31_RS08840
uniprot id: A0A6G7H525
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1288484:G6R31 RS14385
gene id: 1288484:G6R31_RS14385
uniprot id: A0A6G7H8H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1288484:G6R31 RS02535
gene id: 1288484:G6R31_RS02535
uniprot id: A0A6G7H198
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1288484:G6R31 RS12475
gene id: 1288484:G6R31_RS12475
uniprot id: A0A6G7H6M1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1288484:G6R31 RS08535
gene id: 1288484:G6R31_RS08535
uniprot id: A0A6G7H4H4
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

1288484:G6R31 RS08955
gene id: 1288484:G6R31_RS08955
uniprot id: A0A6G7H4F9
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

1288484:G6R31 RS06135
gene id: 1288484:G6R31_RS06135
uniprot id: A0A6G7H2Z0
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1288484:G6R31 RS13675
gene id: 1288484:G6R31_RS13675
uniprot id: A0A6G7H6K5
names: Similarity
messages: Belongs to the IMPACT family.

1288484:G6R31 RS12590
gene id: 1288484:G6R31_RS12590
uniprot id: A0A6G7H6U6
names: Similarity
messages: Belongs to the Nth/MutY family.

1288484:G6R31 RS03405
gene id: 1288484:G6R31_RS03405
uniprot id: A0A6G7H2D7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 15 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1288484:G6R31 RS02155
gene id: 1288484:G6R31_RS02155
uniprot id: A0A6G7H0Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1288484:G6R31 RS12990
gene id: 1288484:G6R31_RS12990
uniprot id: A0A6G7H6C4
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1288484:G6R31 RS15375
gene id: 1288484:G6R31_RS15375
uniprot id: A0A6G7H9F2
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1288484:G6R31 RS13280
gene id: 1288484:G6R31_RS13280
uniprot id: A0A6G7H7I1
names: Subcellular Location Annotation
messages: Membrane

1288484:G6R31 RS05455
gene id: 1288484:G6R31_RS05455
uniprot id: A0A6G7H2M8
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.