1286171:EAL2 RS08150
gene id: 1286171:EAL2_RS08150
uniprot id: W8TGH8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1286171:EAL2 RS01920
gene id: 1286171:EAL2_RS01920
uniprot id: W8TD14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1286171:EAL2 RS04010
gene id: 1286171:EAL2_RS04010
uniprot id: W8T5G2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1286171:EAL2 RS08190
gene id: 1286171:EAL2_RS08190
uniprot id: W8TL65
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1286171:EAL2 RS00455
gene id: 1286171:EAL2_RS00455
uniprot id: W8TGV9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1286171:EAL2 RS09220
gene id: 1286171:EAL2_RS09220
uniprot id: W8TLV3
names: Similarity
messages: Belongs to the class-I fumarase family.

1286171:EAL2 RS08545
gene id: 1286171:EAL2_RS08545
uniprot id: W8T5J4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1286171:EAL2 RS03430
gene id: 1286171:EAL2_RS03430
uniprot id: W8TIE2
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

1286171:EAL2 RS01725
gene id: 1286171:EAL2_RS01725
uniprot id: W8T1R8
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

1286171:EAL2 RS10210
gene id: 1286171:EAL2_RS10210
uniprot id: W8U923
names: Similarity
messages: Belongs to the DEAD box helicase family.

1286171:EAL2 RS11095
gene id: 1286171:EAL2_RS11095
uniprot id: W8U9K6
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1286171:EAL2 RS07350
gene id: 1286171:EAL2_RS07350
uniprot id: W8U7A5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1286171:EAL2 RS01270
gene id: 1286171:EAL2_RS01270
uniprot id: W8U3K4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1286171:EAL2 RS05220
gene id: 1286171:EAL2_RS05220
uniprot id: W8TEU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1286171:EAL2 RS12560
gene id: 1286171:EAL2_RS12560
uniprot id: W8TJ81
names: Subcellular Location Annotation
messages: Cytoplasm

1286171:EAL2 RS13840
gene id: 1286171:EAL2_RS13840
uniprot id: W8TB78
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

1286171:EAL2 RS01345
gene id: 1286171:EAL2_RS01345
uniprot id: W8THB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

1286171:EAL2 RS00700
gene id: 1286171:EAL2_RS00700
uniprot id: W8U3A7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1286171:EAL2 RS04685
gene id: 1286171:EAL2_RS04685
uniprot id: W8U5M9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

1286171:EAL2 RS13555
gene id: 1286171:EAL2_RS13555
uniprot id: W8TPJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1286171:EAL2 RS13515
gene id: 1286171:EAL2_RS13515
uniprot id: W8T8L2
names: Similarity
messages: Belongs to the universal stress protein A family.

1286171:EAL2 RS01860
gene id: 1286171:EAL2_RS01860
uniprot id: W8U405
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1286171:EAL2 RS06640
gene id: 1286171:EAL2_RS06640
uniprot id: W8TFP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1286171:EAL2 RS04895
gene id: 1286171:EAL2_RS04895
uniprot id: W8T3D7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1286171:EAL2 RS10330
gene id: 1286171:EAL2_RS10330
uniprot id: W8TMF1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

1286171:EAL2 RS04470
gene id: 1286171:EAL2_RS04470
uniprot id: W8U5I7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1286171:EAL2 RS07560
gene id: 1286171:EAL2_RS07560
uniprot id: W8T4X0
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

1286171:EAL2 RS01470
gene id: 1286171:EAL2_RS01470
uniprot id: W8THE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1286171:EAL2 RS12555
gene id: 1286171:EAL2_RS12555
uniprot id: W8TNW5
names: Subcellular Location Annotation
messages: Cytoplasm

1286171:EAL2 RS06580
gene id: 1286171:EAL2_RS06580
uniprot id: W8U6S8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1286171:EAL2 RS06060
gene id: 1286171:EAL2_RS06060
uniprot id: W8TFA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1286171:EAL2 RS10390
gene id: 1286171:EAL2_RS10390
uniprot id: W8T909
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

1286171:EAL2 RS10105
gene id: 1286171:EAL2_RS10105
uniprot id: W8T6F7
names: Similarity
messages: Belongs to the internalin family.

1286171:EAL2 RS01930
gene id: 1286171:EAL2_RS01930
uniprot id: W8T4F7
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1286171:EAL2 RS01420
gene id: 1286171:EAL2_RS01420
uniprot id: W8TGN2
names: Similarity
messages: Belongs to the thioredoxin family.

1286171:EAL2 RS00690
gene id: 1286171:EAL2_RS00690
uniprot id: W8T170
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1286171:EAL2 RS06300
gene id: 1286171:EAL2_RS06300
uniprot id: W8TK29
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1286171:EAL2 RS14125
gene id: 1286171:EAL2_RS14125
uniprot id: W8TPZ6
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

1286171:EAL2 RS07435
gene id: 1286171:EAL2_RS07435
uniprot id: W8TG33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1286171:EAL2 RS08725
gene id: 1286171:EAL2_RS08725
uniprot id: W8U854
names: Similarity
messages: Belongs to the peptidase C56 family.

1286171:EAL2 RS06675
gene id: 1286171:EAL2_RS06675
uniprot id: W8T710
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

1286171:EAL2 RS09785
gene id: 1286171:EAL2_RS09785
uniprot id: W8T691
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1286171:EAL2 RS14580
gene id: 1286171:EAL2_RS14580
uniprot id: W8TKK0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1286171:EAL2 RS06020
gene id: 1286171:EAL2_RS06020
uniprot id: W8T6J1
names: Similarity
messages: Belongs to the TlyA family.

1286171:EAL2 RS13455
gene id: 1286171:EAL2_RS13455
uniprot id: W8TPG4
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1286171:EAL2 RS03905
gene id: 1286171:EAL2_RS03905
uniprot id: W8T2V1
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1286171:EAL2 RS12485
gene id: 1286171:EAL2_RS12485
uniprot id: W8UAK5
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1286171:EAL2 RS07910
gene id: 1286171:EAL2_RS07910
uniprot id: W8U7M7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1286171:EAL2 RS07005
gene id: 1286171:EAL2_RS07005
uniprot id: W8U735
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1286171:EAL2 RS04955
gene id: 1286171:EAL2_RS04955
uniprot id: W8TJA8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1286171:EAL2 RS13860
gene id: 1286171:EAL2_RS13860
uniprot id: W8T8U2
names: Function
names: Similarity
names: Subunit
messages: Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization.
messages: Belongs to the HutP family.
messages: Homohexamer.

1286171:EAL2 RS10845
gene id: 1286171:EAL2_RS10845
uniprot id: W8U9E2
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1286171:EAL2 RS07565
gene id: 1286171:EAL2_RS07565
uniprot id: W8T7E7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1286171:EAL2 RS09920
gene id: 1286171:EAL2_RS09920
uniprot id: W8T6B6
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1286171:EAL2 RS00905
gene id: 1286171:EAL2_RS00905
uniprot id: W8TH45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

1286171:EAL2 RS04430
gene id: 1286171:EAL2_RS04430
uniprot id: W8TEF0
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1286171:EAL2 RS08865
gene id: 1286171:EAL2_RS08865
uniprot id: W8T883
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1286171:EAL2 RS00035
gene id: 1286171:EAL2_RS00035
uniprot id: W8T3H0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1286171:EAL2 RS06325
gene id: 1286171:EAL2_RS06325
uniprot id: W8T481
names: Function
names: Similarity
messages: Belongs to the desulfoferrodoxin family.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.

1286171:EAL2 RS07115
gene id: 1286171:EAL2_RS07115
uniprot id: W8TFX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

1286171:EAL2 RS01000
gene id: 1286171:EAL2_RS01000
uniprot id: W8U3H8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1286171:EAL2 RS14870
gene id: 1286171:EAL2_RS14870
uniprot id: W8THN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1286171:EAL2 RS12465
gene id: 1286171:EAL2_RS12465
uniprot id: W8TNU1
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS07970
gene id: 1286171:EAL2_RS07970
uniprot id: W8T561
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1286171:EAL2 RS11260
gene id: 1286171:EAL2_RS11260
uniprot id: W8T761
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS06085
gene id: 1286171:EAL2_RS06085
uniprot id: W8TFB1
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS09380
gene id: 1286171:EAL2_RS09380
uniprot id: W8U8K0
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS00450
gene id: 1286171:EAL2_RS00450
uniprot id: W8U354
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1286171:EAL2 RS07580
gene id: 1286171:EAL2_RS07580
uniprot id: W8TG58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1286171:EAL2 RS07295
gene id: 1286171:EAL2_RS07295
uniprot id: W8T7B0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1286171:EAL2 RS04835
gene id: 1286171:EAL2_RS04835
uniprot id: W8U5R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1286171:EAL2 RS10200
gene id: 1286171:EAL2_RS10200
uniprot id: W8T6H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
messages: Membrane

1286171:EAL2 RS12060
gene id: 1286171:EAL2_RS12060
uniprot id: W8TNK2
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1286171:EAL2 RS10145
gene id: 1286171:EAL2_RS10145
uniprot id: W8TMA8
names: Similarity
messages: Belongs to the peptidase S41A family.

1286171:EAL2 RS08745
gene id: 1286171:EAL2_RS08745
uniprot id: W8T856
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

1286171:EAL2 RS00850
gene id: 1286171:EAL2_RS00850
uniprot id: W8U3E2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1286171:EAL2 RS10810
gene id: 1286171:EAL2_RS10810
uniprot id: W8T6W0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1286171:EAL2 RS10645
gene id: 1286171:EAL2_RS10645
uniprot id: W8THX8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

1286171:EAL2 RS12635
gene id: 1286171:EAL2_RS12635
uniprot id: W8TJ95
names: Similarity
messages: Belongs to the UPF0251 family.

1286171:EAL2 RS11130
gene id: 1286171:EAL2_RS11130
uniprot id: W8TI75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1286171:EAL2 RS08065
gene id: 1286171:EAL2_RS08065
uniprot id: W8U7R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1286171:EAL2 RS11415
gene id: 1286171:EAL2_RS11415
uniprot id: W8T9K8
names: Similarity
messages: Belongs to the CobH/CbiC family.

1286171:EAL2 RS06430
gene id: 1286171:EAL2_RS06430
uniprot id: W8T6T0
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1286171:EAL2 RS11900
gene id: 1286171:EAL2_RS11900
uniprot id: W8T7L4
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

1286171:EAL2 RS11240
gene id: 1286171:EAL2_RS11240
uniprot id: W8T9H3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1286171:EAL2 RS03385
gene id: 1286171:EAL2_RS03385
uniprot id: W8U4T7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
messages: Membrane

1286171:EAL2 RS01680
gene id: 1286171:EAL2_RS01680
uniprot id: W8T4C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1286171:EAL2 RS14560
gene id: 1286171:EAL2_RS14560
uniprot id: W8TQ84
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

1286171:EAL2 RS01460
gene id: 1286171:EAL2_RS01460
uniprot id: W8T459
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1286171:EAL2 RS05265
gene id: 1286171:EAL2_RS05265
uniprot id: W8TJF1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1286171:EAL2 RS09990
gene id: 1286171:EAL2_RS09990
uniprot id: W8THJ7
names: Similarity
messages: Belongs to the CpsD/CapB family.

1286171:EAL2 RS11280
gene id: 1286171:EAL2_RS11280
uniprot id: W8TIB5
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

1286171:EAL2 RS07360
gene id: 1286171:EAL2_RS07360
uniprot id: W8TG21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1286171:EAL2 RS12215
gene id: 1286171:EAL2_RS12215
uniprot id: W8TNN2
names: Similarity
messages: Belongs to the EamA transporter family.

1286171:EAL2 RS07025
gene id: 1286171:EAL2_RS07025
uniprot id: W8T765
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1286171:EAL2 RS09950
gene id: 1286171:EAL2_RS09950
uniprot id: W8T8T9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1286171:EAL2 RS06065
gene id: 1286171:EAL2_RS06065
uniprot id: W8T421
names: Caution
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1286171:EAL2 RS06710
gene id: 1286171:EAL2_RS06710
uniprot id: W8TKE6
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

1286171:EAL2 RS06105
gene id: 1286171:EAL2_RS06105
uniprot id: W8TJY0
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1286171:EAL2 RS14055
gene id: 1286171:EAL2_RS14055
uniprot id: W8TBF5
names: Similarity
messages: Belongs to the hemerythrin family.

1286171:EAL2 RS13405
gene id: 1286171:EAL2_RS13405
uniprot id: W8TPF4
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1286171:EAL2 RS04750
gene id: 1286171:EAL2_RS04750
uniprot id: W8T3B4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1286171:EAL2 RS04900
gene id: 1286171:EAL2_RS04900
uniprot id: W8T5Z1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1286171:EAL2 RS04095
gene id: 1286171:EAL2_RS04095
uniprot id: W8TE59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1286171:EAL2 RS08275
gene id: 1286171:EAL2_RS08275
uniprot id: W8T5D4
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1286171:EAL2 RS08875
gene id: 1286171:EAL2_RS08875
uniprot id: W8TLM0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1286171:EAL2 RS02710
gene id: 1286171:EAL2_RS02710
uniprot id: W8TDE8
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS12680
gene id: 1286171:EAL2_RS12680
uniprot id: W8UAN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1286171:EAL2 RS04755
gene id: 1286171:EAL2_RS04755
uniprot id: W8T5W7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1286171:EAL2 RS03360
gene id: 1286171:EAL2_RS03360
uniprot id: W8TIC7
names: Similarity
messages: Belongs to the RutC family.

1286171:EAL2 RS11470
gene id: 1286171:EAL2_RS11470
uniprot id: W8U9U5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1286171:EAL2 RS10870
gene id: 1286171:EAL2_RS10870
uniprot id: W8U9E7
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1286171:EAL2 RS00910
gene id: 1286171:EAL2_RS00910
uniprot id: W8TCI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

1286171:EAL2 RS08630
gene id: 1286171:EAL2_RS08630
uniprot id: W8U833
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1286171:EAL2 RS14610
gene id: 1286171:EAL2_RS14610
uniprot id: W8TBQ8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the gmhB family.
messages: Cytoplasm
messages: Monomer.

1286171:EAL2 RS06175
gene id: 1286171:EAL2_RS06175
uniprot id: W8U6I0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

1286171:EAL2 RS06525
gene id: 1286171:EAL2_RS06525
uniprot id: W8T6U9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

1286171:EAL2 RS08530
gene id: 1286171:EAL2_RS08530
uniprot id: W8U806
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1286171:EAL2 RS01715
gene id: 1286171:EAL2_RS01715
uniprot id: W8THM2
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

1286171:EAL2 RS12875
gene id: 1286171:EAL2_RS12875
uniprot id: W8UAT5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1286171:EAL2 RS14555
gene id: 1286171:EAL2_RS14555
uniprot id: W8UC04
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.

1286171:EAL2 RS14800
gene id: 1286171:EAL2_RS14800
uniprot id: W8TG88
names: Similarity
messages: Belongs to the UPF0111 family.

1286171:EAL2 RS07425
gene id: 1286171:EAL2_RS07425
uniprot id: W8U7C3
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1286171:EAL2 RS10050
gene id: 1286171:EAL2_RS10050
uniprot id: W8THL1
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1286171:EAL2 RS06755
gene id: 1286171:EAL2_RS06755
uniprot id: W8U6Z5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

1286171:EAL2 RS05225
gene id: 1286171:EAL2_RS05225
uniprot id: W8T3J8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1286171:EAL2 RS00615
gene id: 1286171:EAL2_RS00615
uniprot id: W8T3R3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1286171:EAL2 RS05205
gene id: 1286171:EAL2_RS05205
uniprot id: W8T638
names: Similarity
messages: Belongs to the transpeptidase family.

1286171:EAL2 RS13775
gene id: 1286171:EAL2_RS13775
uniprot id: W8TPQ1
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate ammonia-lyase family.
messages: Homodimer.

1286171:EAL2 RS06850
gene id: 1286171:EAL2_RS06850
uniprot id: W8U711
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1286171:EAL2 RS00050
gene id: 1286171:EAL2_RS00050
uniprot id: W8TC43
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1286171:EAL2 RS02205
gene id: 1286171:EAL2_RS02205
uniprot id: W8T1Z1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1286171:EAL2 RS07885
gene id: 1286171:EAL2_RS07885
uniprot id: W8U7M4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

1286171:EAL2 RS00730
gene id: 1286171:EAL2_RS00730
uniprot id: W8TH10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1286171:EAL2 RS07285
gene id: 1286171:EAL2_RS07285
uniprot id: W8TKP3
names: Similarity
messages: Belongs to the asp23 family.

1286171:EAL2 RS06425
gene id: 1286171:EAL2_RS06425
uniprot id: W8T499
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the encapsulin family. Family 1 subfamily.
messages: Encapsulin nanocompartment

1286171:EAL2 RS00085
gene id: 1286171:EAL2_RS00085
uniprot id: W8TGS1
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

1286171:EAL2 RS08025
gene id: 1286171:EAL2_RS08025
uniprot id: W8U7Q5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1286171:EAL2 RS08085
gene id: 1286171:EAL2_RS08085
uniprot id: W8T7P7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1286171:EAL2 RS00995
gene id: 1286171:EAL2_RS00995
uniprot id: W8T3Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1286171:EAL2 RS07030
gene id: 1286171:EAL2_RS07030
uniprot id: W8U740
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1286171:EAL2 RS13985
gene id: 1286171:EAL2_RS13985
uniprot id: W8TPW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

1286171:EAL2 RS04940
gene id: 1286171:EAL2_RS04940
uniprot id: W8T3E7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

1286171:EAL2 RS08015
gene id: 1286171:EAL2_RS08015
uniprot id: W8T574
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1286171:EAL2 RS10955
gene id: 1286171:EAL2_RS10955
uniprot id: W8TMT1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1286171:EAL2 RS12995
gene id: 1286171:EAL2_RS12995
uniprot id: W8TAL7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1286171:EAL2 RS10365
gene id: 1286171:EAL2_RS10365
uniprot id: W8T905
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1286171:EAL2 RS08140
gene id: 1286171:EAL2_RS08140
uniprot id: W8U7S6
names: Similarity
messages: Belongs to the GSP E family.

1286171:EAL2 RS06370
gene id: 1286171:EAL2_RS06370
uniprot id: W8TFG9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1286171:EAL2 RS06215
gene id: 1286171:EAL2_RS06215
uniprot id: W8T6N4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor.

1286171:EAL2 RS04020
gene id: 1286171:EAL2_RS04020
uniprot id: W8TIR4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1286171:EAL2 RS12310
gene id: 1286171:EAL2_RS12310
uniprot id: W8TJ24
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

1286171:EAL2 RS04760
gene id: 1286171:EAL2_RS04760
uniprot id: W8U5P3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1286171:EAL2 RS00845
gene id: 1286171:EAL2_RS00845
uniprot id: W8T3W4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1286171:EAL2 RS09875
gene id: 1286171:EAL2_RS09875
uniprot id: W8T8S7
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1286171:EAL2 RS05800
gene id: 1286171:EAL2_RS05800
uniprot id: W8TJQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1286171:EAL2 RS08555
gene id: 1286171:EAL2_RS08555
uniprot id: W8U814
names: Similarity
messages: Belongs to the group II decarboxylase family.

1286171:EAL2 RS08465
gene id: 1286171:EAL2_RS08465
uniprot id: W8TGP1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1286171:EAL2 RS08075
gene id: 1286171:EAL2_RS08075
uniprot id: W8TGG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1286171:EAL2 RS00405
gene id: 1286171:EAL2_RS00405
uniprot id: W8U5M3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1286171:EAL2 RS07925
gene id: 1286171:EAL2_RS07925
uniprot id: W8T551
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1286171:EAL2 RS04230
gene id: 1286171:EAL2_RS04230
uniprot id: W8T326
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS13875
gene id: 1286171:EAL2_RS13875
uniprot id: W8TPS2
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS06475
gene id: 1286171:EAL2_RS06475
uniprot id: W8T4A7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1286171:EAL2 RS07835
gene id: 1286171:EAL2_RS07835
uniprot id: W8U7L2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1286171:EAL2 RS14695
gene id: 1286171:EAL2_RS14695
uniprot id: W8THR7
names: Similarity
messages: Belongs to the universal stress protein A family.

1286171:EAL2 RS07530
gene id: 1286171:EAL2_RS07530
uniprot id: W8TKS7
names: Similarity
messages: Belongs to the GSP E family.

1286171:EAL2 RS08220
gene id: 1286171:EAL2_RS08220
uniprot id: W8TGJ1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1286171:EAL2 RS03965
gene id: 1286171:EAL2_RS03965
uniprot id: W8U555
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1286171:EAL2 RS03465
gene id: 1286171:EAL2_RS03465
uniprot id: W8T2L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Membrane

1286171:EAL2 RS12795
gene id: 1286171:EAL2_RS12795
uniprot id: W8T848
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

1286171:EAL2 RS06510
gene id: 1286171:EAL2_RS06510
uniprot id: W8TK75
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1286171:EAL2 RS11300
gene id: 1286171:EAL2_RS11300
uniprot id: W8TN17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1286171:EAL2 RS12405
gene id: 1286171:EAL2_RS12405
uniprot id: W8TJ46
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

1286171:EAL2 RS13900
gene id: 1286171:EAL2_RS13900
uniprot id: W8TPS8
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1286171:EAL2 RS06695
gene id: 1286171:EAL2_RS06695
uniprot id: W8T4I2
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1286171:EAL2 RS05995
gene id: 1286171:EAL2_RS05995
uniprot id: W8U6E6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1286171:EAL2 RS11825
gene id: 1286171:EAL2_RS11825
uniprot id: W8T7K0
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS04695
gene id: 1286171:EAL2_RS04695
uniprot id: W8TEK3
names: Similarity
messages: Belongs to the CvfB family.

1286171:EAL2 RS06095
gene id: 1286171:EAL2_RS06095
uniprot id: W8T6K9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1286171:EAL2 RS10545
gene id: 1286171:EAL2_RS10545
uniprot id: W8TMJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1286171:EAL2 RS00460
gene id: 1286171:EAL2_RS00460
uniprot id: W8TC99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1286171:EAL2 RS00515
gene id: 1286171:EAL2_RS00515
uniprot id: W8T135
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1286171:EAL2 RS11485
gene id: 1286171:EAL2_RS11485
uniprot id: W8T7D7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1286171:EAL2 RS07270
gene id: 1286171:EAL2_RS07270
uniprot id: W8T4R6
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1286171:EAL2 RS04555
gene id: 1286171:EAL2_RS04555
uniprot id: W8TEH4
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

1286171:EAL2 RS13505
gene id: 1286171:EAL2_RS13505
uniprot id: W8TPH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1286171:EAL2 RS00750
gene id: 1286171:EAL2_RS00750
uniprot id: W8U3B9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1286171:EAL2 RS05745
gene id: 1286171:EAL2_RS05745
uniprot id: W8U698
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1286171:EAL2 RS03585
gene id: 1286171:EAL2_RS03585
uniprot id: W8TDV8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1286171:EAL2 RS00580
gene id: 1286171:EAL2_RS00580
uniprot id: W8TCC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation.

1286171:EAL2 RS08535
gene id: 1286171:EAL2_RS08535
uniprot id: W8TLE5
names: Similarity
messages: Belongs to the peptidase C40 family.

1286171:EAL2 RS05525
gene id: 1286171:EAL2_RS05525
uniprot id: W8TEZ4
names: Similarity
messages: Belongs to the peptidase S14 family.

1286171:EAL2 RS13780
gene id: 1286171:EAL2_RS13780
uniprot id: W8TK12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate mutase GlmE subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.

1286171:EAL2 RS07035
gene id: 1286171:EAL2_RS07035
uniprot id: W8TKK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1286171:EAL2 RS06350
gene id: 1286171:EAL2_RS06350
uniprot id: W8T485
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1286171:EAL2 RS06770
gene id: 1286171:EAL2_RS06770
uniprot id: W8T4J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1286171:EAL2 RS10380
gene id: 1286171:EAL2_RS10380
uniprot id: W8THS4
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

1286171:EAL2 RS01805
gene id: 1286171:EAL2_RS01805
uniprot id: W8T4E2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1286171:EAL2 RS02040
gene id: 1286171:EAL2_RS02040
uniprot id: W8T4G6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1286171:EAL2 RS06730
gene id: 1286171:EAL2_RS06730
uniprot id: W8U6Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1286171:EAL2 RS05315
gene id: 1286171:EAL2_RS05315
uniprot id: W8TJF9
names: Similarity
messages: Belongs to the UPF0047 family.

1286171:EAL2 RS14040
gene id: 1286171:EAL2_RS14040
uniprot id: W8TPX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1286171:EAL2 RS05325
gene id: 1286171:EAL2_RS05325
uniprot id: W8T3L7
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1286171:EAL2 RS06035
gene id: 1286171:EAL2_RS06035
uniprot id: W8TFA1
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1286171:EAL2 RS05670
gene id: 1286171:EAL2_RS05670
uniprot id: W8TJN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1286171:EAL2 RS10485
gene id: 1286171:EAL2_RS10485
uniprot id: W8T6P0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1286171:EAL2 RS01745
gene id: 1286171:EAL2_RS01745
uniprot id: W8TCY0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1286171:EAL2 RS03980
gene id: 1286171:EAL2_RS03980
uniprot id: W8T2W3
names: Caution
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1286171:EAL2 RS06145
gene id: 1286171:EAL2_RS06145
uniprot id: W8T6L8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1286171:EAL2 RS01995
gene id: 1286171:EAL2_RS01995
uniprot id: W8U425
names: Similarity
messages: Belongs to the peptidase S16 family.

1286171:EAL2 RS08620
gene id: 1286171:EAL2_RS08620
uniprot id: W8T5K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1286171:EAL2 RS07080
gene id: 1286171:EAL2_RS07080
uniprot id: W8U750
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

1286171:EAL2 RS04500
gene id: 1286171:EAL2_RS04500
uniprot id: W8U5J4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

1286171:EAL2 RS01640
gene id: 1286171:EAL2_RS01640
uniprot id: W8T4C1
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1286171:EAL2 RS06555
gene id: 1286171:EAL2_RS06555
uniprot id: W8U6S3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1286171:EAL2 RS07105
gene id: 1286171:EAL2_RS07105
uniprot id: W8U755
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1286171:EAL2 RS08830
gene id: 1286171:EAL2_RS08830
uniprot id: W8T9T5
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

1286171:EAL2 RS06645
gene id: 1286171:EAL2_RS06645
uniprot id: W8T4H4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1286171:EAL2 RS00720
gene id: 1286171:EAL2_RS00720
uniprot id: W8T3T6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1286171:EAL2 RS03770
gene id: 1286171:EAL2_RS03770
uniprot id: W8U514
names: Similarity
messages: Belongs to the RutC family.

1286171:EAL2 RS08315
gene id: 1286171:EAL2_RS08315
uniprot id: W8TGL0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1286171:EAL2 RS13675
gene id: 1286171:EAL2_RS13675
uniprot id: W8UBC0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

1286171:EAL2 RS10820
gene id: 1286171:EAL2_RS10820
uniprot id: W8U9D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

1286171:EAL2 RS06885
gene id: 1286171:EAL2_RS06885
uniprot id: W8TFT3
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1286171:EAL2 RS12970
gene id: 1286171:EAL2_RS12970
uniprot id: W8TAK9
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS01535
gene id: 1286171:EAL2_RS01535
uniprot id: W8T493
names: Similarity
messages: Belongs to the bacterial flagellin family.

1286171:EAL2 RS04535
gene id: 1286171:EAL2_RS04535
uniprot id: W8TEG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1286171:EAL2 RS15055
gene id: 1286171:EAL2_RS15055
uniprot id: W8TFF9
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

1286171:EAL2 RS07050
gene id: 1286171:EAL2_RS07050
uniprot id: W8T770
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1286171:EAL2 RS07875
gene id: 1286171:EAL2_RS07875
uniprot id: W8T539
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family. L-methionine gamma-lyase subfamily.

1286171:EAL2 RS06460
gene id: 1286171:EAL2_RS06460
uniprot id: W8U6Q2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1286171:EAL2 RS02185
gene id: 1286171:EAL2_RS02185
uniprot id: W8T4J0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1286171:EAL2 RS11475
gene id: 1286171:EAL2_RS11475
uniprot id: W8TN58
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1286171:EAL2 RS04360
gene id: 1286171:EAL2_RS04360
uniprot id: W8U5G9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1286171:EAL2 RS14395
gene id: 1286171:EAL2_RS14395
uniprot id: W8UBX6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1286171:EAL2 RS13070
gene id: 1286171:EAL2_RS13070
uniprot id: W8TAN5
names: Similarity
messages: Belongs to the UPF0371 family.

1286171:EAL2 RS04915
gene id: 1286171:EAL2_RS04915
uniprot id: W8TEP0
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1286171:EAL2 RS07190
gene id: 1286171:EAL2_RS07190
uniprot id: W8TFY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1286171:EAL2 RS06405
gene id: 1286171:EAL2_RS06405
uniprot id: W8T6S5
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS13295
gene id: 1286171:EAL2_RS13295
uniprot id: W8UB35
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS13660
gene id: 1286171:EAL2_RS13660
uniprot id: W8TJY1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1286171:EAL2 RS15560
gene id: 1286171:EAL2_RS15560
uniprot id: W8TIN6
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1286171:EAL2 RS03715
gene id: 1286171:EAL2_RS03715
uniprot id: W8T2R0
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

1286171:EAL2 RS11135
gene id: 1286171:EAL2_RS11135
uniprot id: W8T730
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1286171:EAL2 RS07415
gene id: 1286171:EAL2_RS07415
uniprot id: W8T4U4
names: Similarity
messages: Belongs to the YggT family.

1286171:EAL2 RS00695
gene id: 1286171:EAL2_RS00695
uniprot id: W8T3T0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1286171:EAL2 RS00760
gene id: 1286171:EAL2_RS00760
uniprot id: W8TCG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1286171:EAL2 RS07765
gene id: 1286171:EAL2_RS07765
uniprot id: W8TKW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1286171:EAL2 RS13560
gene id: 1286171:EAL2_RS13560
uniprot id: W8TJV4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1286171:EAL2 RS15625
gene id: 1286171:EAL2_RS15625
uniprot id: W8T1P2
names: Similarity
messages: Belongs to the bacterial flagellin family.

1286171:EAL2 RS01285
gene id: 1286171:EAL2_RS01285
uniprot id: W8T1F6
names: Similarity
messages: Belongs to the EamA transporter family.

1286171:EAL2 RS14345
gene id: 1286171:EAL2_RS14345
uniprot id: W8UBW8
names: Similarity
messages: Belongs to the carbamate kinase family.

1286171:EAL2 RS07120
gene id: 1286171:EAL2_RS07120
uniprot id: W8T4P3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1286171:EAL2 RS08740
gene id: 1286171:EAL2_RS08740
uniprot id: W8T5N4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1286171:EAL2 RS14690
gene id: 1286171:EAL2_RS14690
uniprot id: W8TD18
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

1286171:EAL2 RS03450
gene id: 1286171:EAL2_RS03450
uniprot id: W8U4V2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1286171:EAL2 RS13260
gene id: 1286171:EAL2_RS13260
uniprot id: W8TPC0
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1286171:EAL2 RS14280
gene id: 1286171:EAL2_RS14280
uniprot id: W8TKE1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1286171:EAL2 RS07355
gene id: 1286171:EAL2_RS07355
uniprot id: W8TKQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1286171:EAL2 RS09395
gene id: 1286171:EAL2_RS09395
uniprot id: W8T633
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1286171:EAL2 RS00835
gene id: 1286171:EAL2_RS00835
uniprot id: W8TCH4
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1286171:EAL2 RS06165
gene id: 1286171:EAL2_RS06165
uniprot id: W8T446
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1286171:EAL2 RS00645
gene id: 1286171:EAL2_RS00645
uniprot id: W8U396
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

1286171:EAL2 RS10980
gene id: 1286171:EAL2_RS10980
uniprot id: W8TMT6
names: Similarity
messages: Belongs to the universal stress protein A family.

1286171:EAL2 RS06270
gene id: 1286171:EAL2_RS06270
uniprot id: W8U6K3
names: Similarity
messages: Belongs to the UPF0473 family.

1286171:EAL2 RS04830
gene id: 1286171:EAL2_RS04830
uniprot id: W8T5X9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1286171:EAL2 RS01905
gene id: 1286171:EAL2_RS01905
uniprot id: W8T4F3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1286171:EAL2 RS04090
gene id: 1286171:EAL2_RS04090
uniprot id: W8TIT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

1286171:EAL2 RS13640
gene id: 1286171:EAL2_RS13640
uniprot id: W8T8P3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1286171:EAL2 RS08305
gene id: 1286171:EAL2_RS08305
uniprot id: W8T7U3
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1286171:EAL2 RS01445
gene id: 1286171:EAL2_RS01445
uniprot id: W8THE0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1286171:EAL2 RS11320
gene id: 1286171:EAL2_RS11320
uniprot id: W8U9Q9
names: Similarity
messages: Belongs to the UPF0251 family.

1286171:EAL2 RS01545
gene id: 1286171:EAL2_RS01545
uniprot id: W8THI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1286171:EAL2 RS14155
gene id: 1286171:EAL2_RS14155
uniprot id: W8TKC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1286171:EAL2 RS04315
gene id: 1286171:EAL2_RS04315
uniprot id: W8TJ04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1286171:EAL2 RS02160
gene id: 1286171:EAL2_RS02160
uniprot id: W8T4I5
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.
messages: May be involved in the biosynthesis of molybdopterin.

1286171:EAL2 RS14495
gene id: 1286171:EAL2_RS14495
uniprot id: W8TBN5
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS06155
gene id: 1286171:EAL2_RS06155
uniprot id: W8TJZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

1286171:EAL2 RS13590
gene id: 1286171:EAL2_RS13590
uniprot id: W8T8N1
names: Similarity
messages: Belongs to the UPF0237 family.

1286171:EAL2 RS05885
gene id: 1286171:EAL2_RS05885
uniprot id: W8T6G3
names: Similarity
messages: Belongs to the peptidase S11 family.

1286171:EAL2 RS01635
gene id: 1286171:EAL2_RS01635
uniprot id: W8T1Q2
names: Similarity
messages: Belongs to the HepT RNase toxin family.

1286171:EAL2 RS05875
gene id: 1286171:EAL2_RS05875
uniprot id: W8TF67
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1286171:EAL2 RS14160
gene id: 1286171:EAL2_RS14160
uniprot id: W8TNK2
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1286171:EAL2 RS08205
gene id: 1286171:EAL2_RS08205
uniprot id: W8T7S1
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS09025
gene id: 1286171:EAL2_RS09025
uniprot id: W8TGZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1286171:EAL2 RS00385
gene id: 1286171:EAL2_RS00385
uniprot id: W8TGU9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1286171:EAL2 RS01830
gene id: 1286171:EAL2_RS01830
uniprot id: W8T4E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1286171:EAL2 RS06950
gene id: 1286171:EAL2_RS06950
uniprot id: W8T752
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS12450
gene id: 1286171:EAL2_RS12450
uniprot id: W8TJ54
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1286171:EAL2 RS10045
gene id: 1286171:EAL2_RS10045
uniprot id: W8TM88
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of alpha-methyl-L-serine to D-alanine with tetrahydrofolate (THF) serving as the one-carbon carrier.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1286171:EAL2 RS04285
gene id: 1286171:EAL2_RS04285
uniprot id: W8U5F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

1286171:EAL2 RS12250
gene id: 1286171:EAL2_RS12250
uniprot id: W8TA57
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

1286171:EAL2 RS10495
gene id: 1286171:EAL2_RS10495
uniprot id: W8U979
names: Similarity
messages: Belongs to the universal stress protein A family.

1286171:EAL2 RS01705
gene id: 1286171:EAL2_RS01705
uniprot id: W8T4D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane

1286171:EAL2 RS11700
gene id: 1286171:EAL2_RS11700
uniprot id: W8T7I2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1286171:EAL2 RS06825
gene id: 1286171:EAL2_RS06825
uniprot id: W8T733
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1286171:EAL2 RS09185
gene id: 1286171:EAL2_RS09185
uniprot id: W8T605
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1286171:EAL2 RS01480
gene id: 1286171:EAL2_RS01480
uniprot id: W8T1I6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1286171:EAL2 RS10305
gene id: 1286171:EAL2_RS10305
uniprot id: W8U944
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

1286171:EAL2 RS00220
gene id: 1286171:EAL2_RS00220
uniprot id: W8TC75
names: Similarity
messages: Belongs to the UPF0173 family.

1286171:EAL2 RS13725
gene id: 1286171:EAL2_RS13725
uniprot id: W8UBD5
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1286171:EAL2 RS13155
gene id: 1286171:EAL2_RS13155
uniprot id: W8UB01
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1286171:EAL2 RS08165
gene id: 1286171:EAL2_RS08165
uniprot id: W8TL59
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1286171:EAL2 RS08375
gene id: 1286171:EAL2_RS08375
uniprot id: W8U7X3
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.

1286171:EAL2 RS06235
gene id: 1286171:EAL2_RS06235
uniprot id: W8T462
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

1286171:EAL2 RS04045
gene id: 1286171:EAL2_RS04045
uniprot id: W8TIR9
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

1286171:EAL2 RS06480
gene id: 1286171:EAL2_RS06480
uniprot id: W8U6Q8
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1286171:EAL2 RS00765
gene id: 1286171:EAL2_RS00765
uniprot id: W8T185
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1286171:EAL2 RS00885
gene id: 1286171:EAL2_RS00885
uniprot id: W8TCI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1286171:EAL2 RS10725
gene id: 1286171:EAL2_RS10725
uniprot id: W8THZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1286171:EAL2 RS03500
gene id: 1286171:EAL2_RS03500
uniprot id: W8U4W4
names: Similarity
messages: Belongs to the Lgt family.

1286171:EAL2 RS13325
gene id: 1286171:EAL2_RS13325
uniprot id: W8TPE0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1286171:EAL2 RS00895
gene id: 1286171:EAL2_RS00895
uniprot id: W8T3X2
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1286171:EAL2 RS00830
gene id: 1286171:EAL2_RS00830
uniprot id: W8TH30
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1286171:EAL2 RS06855
gene id: 1286171:EAL2_RS06855
uniprot id: W8TKH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1286171:EAL2 RS02415
gene id: 1286171:EAL2_RS02415
uniprot id: W8U4B0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1286171:EAL2 RS04730
gene id: 1286171:EAL2_RS04730
uniprot id: W8T5W5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1286171:EAL2 RS14645
gene id: 1286171:EAL2_RS14645
uniprot id: W8TKL4
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

1286171:EAL2 RS09215
gene id: 1286171:EAL2_RS09215
uniprot id: W8T8H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

1286171:EAL2 RS00740
gene id: 1286171:EAL2_RS00740
uniprot id: W8T180
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1286171:EAL2 RS04975
gene id: 1286171:EAL2_RS04975
uniprot id: W8U5U1
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1286171:EAL2 RS09190
gene id: 1286171:EAL2_RS09190
uniprot id: W8T8H0
names: Similarity
messages: Belongs to the UPF0735 family.

1286171:EAL2 RS06100
gene id: 1286171:EAL2_RS06100
uniprot id: W8U6G5
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1286171:EAL2 RS00225
gene id: 1286171:EAL2_RS00225
uniprot id: W8T0Z6
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS01005
gene id: 1286171:EAL2_RS01005
uniprot id: W8TH69
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

1286171:EAL2 RS12730
gene id: 1286171:EAL2_RS12730
uniprot id: W8UAP9
names: Similarity
messages: Belongs to the glutamate synthase family.

1286171:EAL2 RS07555
gene id: 1286171:EAL2_RS07555
uniprot id: W8TG52
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1286171:EAL2 RS12045
gene id: 1286171:EAL2_RS12045
uniprot id: W8TIW8
names: Similarity
messages: Belongs to the pirin family.

1286171:EAL2 RS00230
gene id: 1286171:EAL2_RS00230
uniprot id: W8T3K2
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1286171:EAL2 RS06595
gene id: 1286171:EAL2_RS06595
uniprot id: W8T4F5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1286171:EAL2 RS08060
gene id: 1286171:EAL2_RS08060
uniprot id: W8T7P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1286171:EAL2 RS04055
gene id: 1286171:EAL2_RS04055
uniprot id: W8T9T5
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

1286171:EAL2 RS07850
gene id: 1286171:EAL2_RS07850
uniprot id: W8T533
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1286171:EAL2 RS07695
gene id: 1286171:EAL2_RS07695
uniprot id: W8TG83
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS00190
gene id: 1286171:EAL2_RS00190
uniprot id: W8TGT8
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1286171:EAL2 RS00620
gene id: 1286171:EAL2_RS00620
uniprot id: W8U389
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1286171:EAL2 RS05905
gene id: 1286171:EAL2_RS05905
uniprot id: W8T3Y8
names: Function
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

1286171:EAL2 RS00960
gene id: 1286171:EAL2_RS00960
uniprot id: W8TCJ7
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1286171:EAL2 RS14185
gene id: 1286171:EAL2_RS14185
uniprot id: W8T942
names: Similarity
messages: Belongs to the EamA transporter family.

1286171:EAL2 RS12705
gene id: 1286171:EAL2_RS12705
uniprot id: W8UAP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1286171:EAL2 RS04345
gene id: 1286171:EAL2_RS04345
uniprot id: W8TED6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1286171:EAL2 RS00915
gene id: 1286171:EAL2_RS00915
uniprot id: W8T1B9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1286171:EAL2 RS06210
gene id: 1286171:EAL2_RS06210
uniprot id: W8T456
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1286171:EAL2 RS06715
gene id: 1286171:EAL2_RS06715
uniprot id: W8TFQ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1286171:EAL2 RS15705
gene id: 1286171:EAL2_RS15705
uniprot id: W8U5R5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1286171:EAL2 RS05780
gene id: 1286171:EAL2_RS05780
uniprot id: W8TF46
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS00380
gene id: 1286171:EAL2_RS00380
uniprot id: W8U335
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1286171:EAL2 RS03725
gene id: 1286171:EAL2_RS03725
uniprot id: W8U505
names: Cofactor
names: Similarity
messages: Belongs to the PHP family.
messages: Binds 3 Zn(2+) ions per subunit.

1286171:EAL2 RS04795
gene id: 1286171:EAL2_RS04795
uniprot id: W8TEL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1286171:EAL2 RS07345
gene id: 1286171:EAL2_RS07345
uniprot id: W8T7B8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1286171:EAL2 RS00670
gene id: 1286171:EAL2_RS00670
uniprot id: W8T3S4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1286171:EAL2 RS05935
gene id: 1286171:EAL2_RS05935
uniprot id: W8TF79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1286171:EAL2 RS05860
gene id: 1286171:EAL2_RS05860
uniprot id: W8T6F8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1286171:EAL2 RS05725
gene id: 1286171:EAL2_RS05725
uniprot id: W8TJP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1286171:EAL2 RS06800
gene id: 1286171:EAL2_RS06800
uniprot id: W8T729
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

1286171:EAL2 RS05735
gene id: 1286171:EAL2_RS05735
uniprot id: W8T3V0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1286171:EAL2 RS05855
gene id: 1286171:EAL2_RS05855
uniprot id: W8T3X6
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

1286171:EAL2 RS04950
gene id: 1286171:EAL2_RS04950
uniprot id: W8U5T6
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1286171:EAL2 RS10615
gene id: 1286171:EAL2_RS10615
uniprot id: W8TMK8
names: Similarity
messages: Belongs to the DEAD box helicase family.

1286171:EAL2 RS07670
gene id: 1286171:EAL2_RS07670
uniprot id: W8TG78
names: Similarity
messages: Belongs to the citrate synthase family.

1286171:EAL2 RS00865
gene id: 1286171:EAL2_RS00865
uniprot id: W8T1A7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1286171:EAL2 RS00925
gene id: 1286171:EAL2_RS00925
uniprot id: W8U3G1
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1286171:EAL2 RS05965
gene id: 1286171:EAL2_RS05965
uniprot id: W8T6I0
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1286171:EAL2 RS00665
gene id: 1286171:EAL2_RS00665
uniprot id: W8TCF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1286171:EAL2 RS00090
gene id: 1286171:EAL2_RS00090
uniprot id: W8TC49
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1286171:EAL2 RS02010
gene id: 1286171:EAL2_RS02010
uniprot id: W8T1W1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1286171:EAL2 RS07645
gene id: 1286171:EAL2_RS07645
uniprot id: W8TKU3
names: Similarity
messages: Belongs to the universal stress protein A family.

1286171:EAL2 RS11420
gene id: 1286171:EAL2_RS11420
uniprot id: W8U9T2
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

1286171:EAL2 RS00855
gene id: 1286171:EAL2_RS00855
uniprot id: W8TH34
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1286171:EAL2 RS10715
gene id: 1286171:EAL2_RS10715
uniprot id: W8U9B6
names: Similarity
messages: Belongs to the YjdM family.

1286171:EAL2 RS13735
gene id: 1286171:EAL2_RS13735
uniprot id: W8TJZ8
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1286171:EAL2 RS04825
gene id: 1286171:EAL2_RS04825
uniprot id: W8T3C5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1286171:EAL2 RS07200
gene id: 1286171:EAL2_RS07200
uniprot id: W8T795
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1286171:EAL2 RS10060
gene id: 1286171:EAL2_RS10060
uniprot id: W8T8V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1286171:EAL2 RS00775
gene id: 1286171:EAL2_RS00775
uniprot id: W8U3C4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1286171:EAL2 RS03275
gene id: 1286171:EAL2_RS03275
uniprot id: W8U4R5
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1286171:EAL2 RS02225
gene id: 1286171:EAL2_RS02225
uniprot id: W8TD73
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1286171:EAL2 RS03370
gene id: 1286171:EAL2_RS03370
uniprot id: W8TDR3
names: Similarity
messages: Belongs to the SfsA family.

1286171:EAL2 RS07465
gene id: 1286171:EAL2_RS07465
uniprot id: W8T4V2
names: Similarity
messages: Belongs to the TelA family.

1286171:EAL2 RS01505
gene id: 1286171:EAL2_RS01505
uniprot id: W8T1J2
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

1286171:EAL2 RS11355
gene id: 1286171:EAL2_RS11355
uniprot id: W8TID4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1286171:EAL2 RS01245
gene id: 1286171:EAL2_RS01245
uniprot id: W8T414
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1286171:EAL2 RS05700
gene id: 1286171:EAL2_RS05700
uniprot id: W8TJN7
names: Similarity
messages: Belongs to the peptidase C40 family.

1286171:EAL2 RS15700
gene id: 1286171:EAL2_RS15700
uniprot id: W8T5Y3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1286171:EAL2 RS05960
gene id: 1286171:EAL2_RS05960
uniprot id: W8T3Z8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1286171:EAL2 RS06760
gene id: 1286171:EAL2_RS06760
uniprot id: W8TKF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1286171:EAL2 RS13850
gene id: 1286171:EAL2_RS13850
uniprot id: W8TPR6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1286171:EAL2 RS05835
gene id: 1286171:EAL2_RS05835
uniprot id: W8T3X1
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1286171:EAL2 RS03735
gene id: 1286171:EAL2_RS03735
uniprot id: W8TDY9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1286171:EAL2 RS14380
gene id: 1286171:EAL2_RS14380
uniprot id: W8TKG2
names: Similarity
messages: Belongs to the CdaR family.

1286171:EAL2 RS04160
gene id: 1286171:EAL2_RS04160
uniprot id: W8U5D3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1286171:EAL2 RS03550
gene id: 1286171:EAL2_RS03550
uniprot id: W8U4X3
names: Similarity
messages: Belongs to the EamA transporter family.

1286171:EAL2 RS00235
gene id: 1286171:EAL2_RS00235
uniprot id: W8U330
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1286171:EAL2 RS00890
gene id: 1286171:EAL2_RS00890
uniprot id: W8T1B3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1286171:EAL2 RS04970
gene id: 1286171:EAL2_RS04970
uniprot id: W8T604
names: Similarity
messages: Belongs to the CinA family.

1286171:EAL2 RS13460
gene id: 1286171:EAL2_RS13460
uniprot id: W8TJT2
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

1286171:EAL2 RS04660
gene id: 1286171:EAL2_RS04660
uniprot id: W8U5M3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1286171:EAL2 RS01215
gene id: 1286171:EAL2_RS01215
uniprot id: W8T1E4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1286171:EAL2 RS12955
gene id: 1286171:EAL2_RS12955
uniprot id: W8TP44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1286171:EAL2 RS12170
gene id: 1286171:EAL2_RS12170
uniprot id: W8TIZ1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1286171:EAL2 RS05035
gene id: 1286171:EAL2_RS05035
uniprot id: W8TEQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1286171:EAL2 RS08525
gene id: 1286171:EAL2_RS08525
uniprot id: W8T800
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1286171:EAL2 RS14260
gene id: 1286171:EAL2_RS14260
uniprot id: W8T956
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1286171:EAL2 RS06310
gene id: 1286171:EAL2_RS06310
uniprot id: W8T477
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1286171:EAL2 RS10080
gene id: 1286171:EAL2_RS10080
uniprot id: W8T6F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

1286171:EAL2 RS02095
gene id: 1286171:EAL2_RS02095
uniprot id: W8THT5
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1286171:EAL2 RS06455
gene id: 1286171:EAL2_RS06455
uniprot id: W8T6T4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1286171:EAL2 RS11060
gene id: 1286171:EAL2_RS11060
uniprot id: W8T9D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1286171:EAL2 RS06250
gene id: 1286171:EAL2_RS06250
uniprot id: W8TK17
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1286171:EAL2 RS13470
gene id: 1286171:EAL2_RS13470
uniprot id: W8TAY3
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

1286171:EAL2 RS12175
gene id: 1286171:EAL2_RS12175
uniprot id: W8T7Q4
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS00790
gene id: 1286171:EAL2_RS00790
uniprot id: W8T192
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1286171:EAL2 RS07960
gene id: 1286171:EAL2_RS07960
uniprot id: W8TL11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1286171:EAL2 RS09475
gene id: 1286171:EAL2_RS09475
uniprot id: W8THA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1286171:EAL2 RS10940
gene id: 1286171:EAL2_RS10940
uniprot id: W8T9A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

1286171:EAL2 RS01700
gene id: 1286171:EAL2_RS01700
uniprot id: W8T1R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

1286171:EAL2 RS03045
gene id: 1286171:EAL2_RS03045
uniprot id: W8T2D6
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

1286171:EAL2 RS05015
gene id: 1286171:EAL2_RS05015
uniprot id: W8TEQ6
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1286171:EAL2 RS01890
gene id: 1286171:EAL2_RS01890
uniprot id: W8THQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1286171:EAL2 RS14005
gene id: 1286171:EAL2_RS14005
uniprot id: W8TBE6
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS09825
gene id: 1286171:EAL2_RS09825
uniprot id: W8T699
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

1286171:EAL2 RS13800
gene id: 1286171:EAL2_RS13800
uniprot id: W8TPQ6
names: Subcellular Location Annotation
messages: Cytoplasm

1286171:EAL2 RS08070
gene id: 1286171:EAL2_RS08070
uniprot id: W8TL38
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1286171:EAL2 RS00435
gene id: 1286171:EAL2_RS00435
uniprot id: W8TC93
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1286171:EAL2 RS14700
gene id: 1286171:EAL2_RS14700
uniprot id: W8TI00
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1286171:EAL2 RS06380
gene id: 1286171:EAL2_RS06380
uniprot id: W8T6S0
names: Caution
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1286171:EAL2 RS05235
gene id: 1286171:EAL2_RS05235
uniprot id: W8U5Z3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1286171:EAL2 RS11170
gene id: 1286171:EAL2_RS11170
uniprot id: W8U9M3
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1286171:EAL2 RS13265
gene id: 1286171:EAL2_RS13265
uniprot id: W8TJM9
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1286171:EAL2 RS12435
gene id: 1286171:EAL2_RS12435
uniprot id: W8TA93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1286171:EAL2 RS03985
gene id: 1286171:EAL2_RS03985
uniprot id: W8T5F7
names: Similarity
messages: Belongs to the ketopantoate reductase family.

1286171:EAL2 RS03455
gene id: 1286171:EAL2_RS03455
uniprot id: W8TIE6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
messages: Homodimer.

1286171:EAL2 RS00440
gene id: 1286171:EAL2_RS00440
uniprot id: W8T118
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1286171:EAL2 RS08985
gene id: 1286171:EAL2_RS08985
uniprot id: W8T5U2
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

1286171:EAL2 RS06610
gene id: 1286171:EAL2_RS06610
uniprot id: W8TKB9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1286171:EAL2 RS05075
gene id: 1286171:EAL2_RS05075
uniprot id: W8U5W3
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

1286171:EAL2 RS00550
gene id: 1286171:EAL2_RS00550
uniprot id: W8U373
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

1286171:EAL2 RS07675
gene id: 1286171:EAL2_RS07675
uniprot id: W8T4Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

1286171:EAL2 RS12870
gene id: 1286171:EAL2_RS12870
uniprot id: W8T866
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1286171:EAL2 RS09480
gene id: 1286171:EAL2_RS09480
uniprot id: W8T644
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

1286171:EAL2 RS06765
gene id: 1286171:EAL2_RS06765
uniprot id: W8TFR3
names: Similarity
messages: Belongs to the MotB family.

1286171:EAL2 RS09110
gene id: 1286171:EAL2_RS09110
uniprot id: W8T8G5
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1286171:EAL2 RS07735
gene id: 1286171:EAL2_RS07735
uniprot id: W8U7J3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1286171:EAL2 RS04445
gene id: 1286171:EAL2_RS04445
uniprot id: W8U5I4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1286171:EAL2 RS04220
gene id: 1286171:EAL2_RS04220
uniprot id: W8TIY8
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1286171:EAL2 RS09555
gene id: 1286171:EAL2_RS09555
uniprot id: W8U8N4
names: Similarity
messages: Belongs to the DprA/Smf family.

1286171:EAL2 RS10730
gene id: 1286171:EAL2_RS10730
uniprot id: W8T6U4
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS11395
gene id: 1286171:EAL2_RS11395
uniprot id: W8U9S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1286171:EAL2 RS00390
gene id: 1286171:EAL2_RS00390
uniprot id: W8T108
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1286171:EAL2 RS05955
gene id: 1286171:EAL2_RS05955
uniprot id: W8TF84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1286171:EAL2 RS01030
gene id: 1286171:EAL2_RS01030
uniprot id: W8TH74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1286171:EAL2 RS10855
gene id: 1286171:EAL2_RS10855
uniprot id: W8TI19
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

1286171:EAL2 RS03875
gene id: 1286171:EAL2_RS03875
uniprot id: W8TE19
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS07955
gene id: 1286171:EAL2_RS07955
uniprot id: W8U7P0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1286171:EAL2 RS04000
gene id: 1286171:EAL2_RS04000
uniprot id: W8TE39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1286171:EAL2 RS13620
gene id: 1286171:EAL2_RS13620
uniprot id: W8TB19
names: Similarity
messages: Belongs to the EamA transporter family.

1286171:EAL2 RS06120
gene id: 1286171:EAL2_RS06120
uniprot id: W8T6L4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1286171:EAL2 RS04870
gene id: 1286171:EAL2_RS04870
uniprot id: W8T3D3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1286171:EAL2 RS02180
gene id: 1286171:EAL2_RS02180
uniprot id: W8T1Y8
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1286171:EAL2 RS04985
gene id: 1286171:EAL2_RS04985
uniprot id: W8TEQ2
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS05865
gene id: 1286171:EAL2_RS05865
uniprot id: W8U6C3
names: Similarity
messages: Belongs to the RutC family.

1286171:EAL2 RS06650
gene id: 1286171:EAL2_RS06650
uniprot id: W8T706
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1286171:EAL2 RS00810
gene id: 1286171:EAL2_RS00810
uniprot id: W8TCG9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1286171:EAL2 RS08850
gene id: 1286171:EAL2_RS08850
uniprot id: W8TLL5
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1286171:EAL2 RS07990
gene id: 1286171:EAL2_RS07990
uniprot id: W8TGE4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

1286171:EAL2 RS04065
gene id: 1286171:EAL2_RS04065
uniprot id: W8TIS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1286171:EAL2 RS02155
gene id: 1286171:EAL2_RS02155
uniprot id: W8T1Y5
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1286171:EAL2 RS06895
gene id: 1286171:EAL2_RS06895
uniprot id: W8T745
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1286171:EAL2 RS01895
gene id: 1286171:EAL2_RS01895
uniprot id: W8TD08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1286171:EAL2 RS04270
gene id: 1286171:EAL2_RS04270
uniprot id: W8TEC2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Non-allosteric.

1286171:EAL2 RS14180
gene id: 1286171:EAL2_RS14180
uniprot id: W8TKC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1286171:EAL2 RS13855
gene id: 1286171:EAL2_RS13855
uniprot id: W8TK32
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

1286171:EAL2 RS06970
gene id: 1286171:EAL2_RS06970
uniprot id: W8T4M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1286171:EAL2 RS12660
gene id: 1286171:EAL2_RS12660
uniprot id: W8TJA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1286171:EAL2 RS05270
gene id: 1286171:EAL2_RS05270
uniprot id: W8TEU8
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1286171:EAL2 RS13905
gene id: 1286171:EAL2_RS13905
uniprot id: W8TK44
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS12900
gene id: 1286171:EAL2_RS12900
uniprot id: W8UAU1
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1286171:EAL2 RS00165
gene id: 1286171:EAL2_RS00165
uniprot id: W8TGT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1286171:EAL2 RS06655
gene id: 1286171:EAL2_RS06655
uniprot id: W8U6Y0
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1286171:EAL2 RS01495
gene id: 1286171:EAL2_RS01495
uniprot id: W8THF4
names: Similarity
messages: Belongs to the UPF0175 family.

1286171:EAL2 RS08605
gene id: 1286171:EAL2_RS08605
uniprot id: W8U826
names: Similarity
messages: Belongs to the GARS family.

1286171:EAL2 RS06615
gene id: 1286171:EAL2_RS06615
uniprot id: W8TFN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1286171:EAL2 RS06805
gene id: 1286171:EAL2_RS06805
uniprot id: W8U703
names: Subcellular Location Annotation
messages: Cytoplasm

1286171:EAL2 RS00410
gene id: 1286171:EAL2_RS00410
uniprot id: W8TC87
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1286171:EAL2 RS13140
gene id: 1286171:EAL2_RS13140
uniprot id: W8TJJ8
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS09695
gene id: 1286171:EAL2_RS09695
uniprot id: W8U8R4
names: Similarity
messages: Belongs to the peptidase S14 family.

1286171:EAL2 RS08640
gene id: 1286171:EAL2_RS08640
uniprot id: W8TGS7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1286171:EAL2 RS00755
gene id: 1286171:EAL2_RS00755
uniprot id: W8TH17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1286171:EAL2 RS04840
gene id: 1286171:EAL2_RS04840
uniprot id: W8TEN0
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

1286171:EAL2 RS12425
gene id: 1286171:EAL2_RS12425
uniprot id: W8TNT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1286171:EAL2 RS02210
gene id: 1286171:EAL2_RS02210
uniprot id: W8T4J5
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1286171:EAL2 RS00200
gene id: 1286171:EAL2_RS00200
uniprot id: W8T0Z1
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

1286171:EAL2 RS11325
gene id: 1286171:EAL2_RS11325
uniprot id: W8TIC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1286171:EAL2 RS13055
gene id: 1286171:EAL2_RS13055
uniprot id: W8TJI1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1286171:EAL2 RS13990
gene id: 1286171:EAL2_RS13990
uniprot id: W8TK97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1286171:EAL2 RS04665
gene id: 1286171:EAL2_RS04665
uniprot id: W8TJ59
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1286171:EAL2 RS00685
gene id: 1286171:EAL2_RS00685
uniprot id: W8TCE7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1286171:EAL2 RS08890
gene id: 1286171:EAL2_RS08890
uniprot id: W8T888
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1286171:EAL2 RS01550
gene id: 1286171:EAL2_RS01550
uniprot id: W8TCV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1286171:EAL2 RS07390
gene id: 1286171:EAL2_RS07390
uniprot id: W8T4T9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1286171:EAL2 RS11250
gene id: 1286171:EAL2_RS11250
uniprot id: W8TN06
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1286171:EAL2 RS10920
gene id: 1286171:EAL2_RS10920
uniprot id: W8U9F8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1286171:EAL2 RS00185
gene id: 1286171:EAL2_RS00185
uniprot id: W8U318
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1286171:EAL2 RS04025
gene id: 1286171:EAL2_RS04025
uniprot id: W8TE44
names: Similarity
messages: Belongs to the CarB family.

1286171:EAL2 RS04780
gene id: 1286171:EAL2_RS04780
uniprot id: W8T5X1
names: Similarity
messages: Belongs to the IMPACT family.

1286171:EAL2 RS03215
gene id: 1286171:EAL2_RS03215
uniprot id: W8TDN7
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1286171:EAL2 RS03640
gene id: 1286171:EAL2_RS03640
uniprot id: W8T2P7
names: Similarity
messages: Belongs to the HypE family.

1286171:EAL2 RS02015
gene id: 1286171:EAL2_RS02015
uniprot id: W8T4G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

1286171:EAL2 RS07095
gene id: 1286171:EAL2_RS07095
uniprot id: W8T4P0
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1286171:EAL2 RS08485
gene id: 1286171:EAL2_RS08485
uniprot id: W8TLD3
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1286171:EAL2 RS08385
gene id: 1286171:EAL2_RS08385
uniprot id: W8T5G1
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

1286171:EAL2 RS06725
gene id: 1286171:EAL2_RS06725
uniprot id: W8T717
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1286171:EAL2 RS10865
gene id: 1286171:EAL2_RS10865
uniprot id: W8T996
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1286171:EAL2 RS07335
gene id: 1286171:EAL2_RS07335
uniprot id: W8TG16
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1286171:EAL2 RS01025
gene id: 1286171:EAL2_RS01025
uniprot id: W8U3I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1286171:EAL2 RS12745
gene id: 1286171:EAL2_RS12745
uniprot id: W8T837
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

1286171:EAL2 RS03205
gene id: 1286171:EAL2_RS03205
uniprot id: W8TIA0
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1286171:EAL2 RS03085
gene id: 1286171:EAL2_RS03085
uniprot id: W8TI82
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).

1286171:EAL2 RS08520
gene id: 1286171:EAL2_RS08520
uniprot id: W8T5J0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1286171:EAL2 RS13385
gene id: 1286171:EAL2_RS13385
uniprot id: W8TJR3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1286171:EAL2 RS14210
gene id: 1286171:EAL2_RS14210
uniprot id: W8TKC8
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS02500
gene id: 1286171:EAL2_RS02500
uniprot id: W8TDB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1286171:EAL2 RS09065
gene id: 1286171:EAL2_RS09065
uniprot id: W8U8F1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1286171:EAL2 RS11065
gene id: 1286171:EAL2_RS11065
uniprot id: W8U9J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

1286171:EAL2 RS00010
gene id: 1286171:EAL2_RS00010
uniprot id: W8T3G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1286171:EAL2 RS12305
gene id: 1286171:EAL2_RS12305
uniprot id: W8TNQ2
names: Cofactor
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1286171:EAL2 RS06335
gene id: 1286171:EAL2_RS06335
uniprot id: W8U6M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

1286171:EAL2 RS06320
gene id: 1286171:EAL2_RS06320
uniprot id: W8TK34
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class U subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

1286171:EAL2 RS06940
gene id: 1286171:EAL2_RS06940
uniprot id: W8TFU3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1286171:EAL2 RS00920
gene id: 1286171:EAL2_RS00920
uniprot id: W8T3X8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1286171:EAL2 RS04215
gene id: 1286171:EAL2_RS04215
uniprot id: W8U5E5
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1286171:EAL2 RS01010
gene id: 1286171:EAL2_RS01010
uniprot id: W8TCL1
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

1286171:EAL2 RS04540
gene id: 1286171:EAL2_RS04540
uniprot id: W8T377
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1286171:EAL2 RS03590
gene id: 1286171:EAL2_RS03590
uniprot id: W8T2N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1286171:EAL2 RS05145
gene id: 1286171:EAL2_RS05145
uniprot id: W8TES6
names: Similarity
messages: Belongs to the HepT RNase toxin family.

1286171:EAL2 RS10710
gene id: 1286171:EAL2_RS10710
uniprot id: W8T970
names: Similarity
messages: Belongs to the DapB family.

1286171:EAL2 RS01780
gene id: 1286171:EAL2_RS01780
uniprot id: W8T4E1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1286171:EAL2 RS07690
gene id: 1286171:EAL2_RS07690
uniprot id: W8TKV3
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS03320
gene id: 1286171:EAL2_RS03320
uniprot id: W8T511
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

1286171:EAL2 RS08685
gene id: 1286171:EAL2_RS08685
uniprot id: W8TLH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1286171:EAL2 RS08680
gene id: 1286171:EAL2_RS08680
uniprot id: W8U844
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1286171:EAL2 RS08515
gene id: 1286171:EAL2_RS08515
uniprot id: W8TGQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1286171:EAL2 RS13195
gene id: 1286171:EAL2_RS13195
uniprot id: W8T8D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1286171:EAL2 RS12285
gene id: 1286171:EAL2_RS12285
uniprot id: W8TNP7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1286171:EAL2 RS08595
gene id: 1286171:EAL2_RS08595
uniprot id: W8T5K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1286171:EAL2 RS15020
gene id: 1286171:EAL2_RS15020
uniprot id: W8TE79
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS07865
gene id: 1286171:EAL2_RS07865
uniprot id: W8TKZ0
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1286171:EAL2 RS08370
gene id: 1286171:EAL2_RS08370
uniprot id: W8T7W0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1286171:EAL2 RS10900
gene id: 1286171:EAL2_RS10900
uniprot id: W8TMR9
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS00820
gene id: 1286171:EAL2_RS00820
uniprot id: W8T3V9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1286171:EAL2 RS12700
gene id: 1286171:EAL2_RS12700
uniprot id: W8TAE3
names: Similarity
messages: Belongs to the TrpF family.

1286171:EAL2 RS11225
gene id: 1286171:EAL2_RS11225
uniprot id: W8TN01
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1286171:EAL2 RS13880
gene id: 1286171:EAL2_RS13880
uniprot id: W8TK38
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1286171:EAL2 RS06015
gene id: 1286171:EAL2_RS06015
uniprot id: W8T410
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1286171:EAL2 RS00635
gene id: 1286171:EAL2_RS00635
uniprot id: W8T160
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1286171:EAL2 RS07205
gene id: 1286171:EAL2_RS07205
uniprot id: W8U774
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1286171:EAL2 RS10675
gene id: 1286171:EAL2_RS10675
uniprot id: W8T6T3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DbpA subfamily.
messages: Contains an N-terminal domain that binds non-specifically to RNA and a C-terminal domain that binds specifically and tightly to hairpin 92 of 23S rRNA.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes.

1286171:EAL2 RS08880
gene id: 1286171:EAL2_RS08880
uniprot id: W8TGX0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1286171:EAL2 RS04185
gene id: 1286171:EAL2_RS04185
uniprot id: W8TIY1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1286171:EAL2 RS04610
gene id: 1286171:EAL2_RS04610
uniprot id: W8T5U8
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

1286171:EAL2 RS07020
gene id: 1286171:EAL2_RS07020
uniprot id: W8T4N0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1286171:EAL2 RS10175
gene id: 1286171:EAL2_RS10175
uniprot id: W8T6H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1286171:EAL2 RS12200
gene id: 1286171:EAL2_RS12200
uniprot id: W8T7Q9
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1286171:EAL2 RS00950
gene id: 1286171:EAL2_RS00950
uniprot id: W8U3G6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1286171:EAL2 RS08565
gene id: 1286171:EAL2_RS08565
uniprot id: W8TGR0
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1286171:EAL2 RS01360
gene id: 1286171:EAL2_RS01360
uniprot id: W8T439
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1286171:EAL2 RS11340
gene id: 1286171:EAL2_RS11340
uniprot id: W8U9R5
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

1286171:EAL2 RS03375
gene id: 1286171:EAL2_RS03375
uniprot id: W8T2J3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1286171:EAL2 RS10260
gene id: 1286171:EAL2_RS10260
uniprot id: W8TMD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1286171:EAL2 RS11230
gene id: 1286171:EAL2_RS11230
uniprot id: W8TIA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1286171:EAL2 RS08790
gene id: 1286171:EAL2_RS08790
uniprot id: W8T868
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1286171:EAL2 RS01880
gene id: 1286171:EAL2_RS01880
uniprot id: W8T4F1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1286171:EAL2 RS07380
gene id: 1286171:EAL2_RS07380
uniprot id: W8TKQ6
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

1286171:EAL2 RS08810
gene id: 1286171:EAL2_RS08810
uniprot id: W8TLK3
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

1286171:EAL2 RS01375
gene id: 1286171:EAL2_RS01375
uniprot id: W8T1G9
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

1286171:EAL2 RS05465
gene id: 1286171:EAL2_RS05465
uniprot id: W8T3P4
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.

1286171:EAL2 RS08215
gene id: 1286171:EAL2_RS08215
uniprot id: W8TL71
names: Similarity
messages: Belongs to the GSP E family.

1286171:EAL2 RS00540
gene id: 1286171:EAL2_RS00540
uniprot id: W8T140
names: Similarity
messages: Belongs to the class II ribonucleoside-triphosphate reductase family.

1286171:EAL2 RS04050
gene id: 1286171:EAL2_RS04050
uniprot id: W8TE49
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

1286171:EAL2 RS14245
gene id: 1286171:EAL2_RS14245
uniprot id: W8TBI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1286171:EAL2 RS04800
gene id: 1286171:EAL2_RS04800
uniprot id: W8T3C1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1286171:EAL2 RS09545
gene id: 1286171:EAL2_RS09545
uniprot id: W8T655
names: Similarity
messages: Belongs to the NadC/ModD family.

1286171:EAL2 RS08080
gene id: 1286171:EAL2_RS08080
uniprot id: W8T591
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1286171:EAL2 RS10455
gene id: 1286171:EAL2_RS10455
uniprot id: W8THT8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1286171:EAL2 RS07475
gene id: 1286171:EAL2_RS07475
uniprot id: W8U7D5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1286171:EAL2 RS09375
gene id: 1286171:EAL2_RS09375
uniprot id: W8T8K1
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

1286171:EAL2 RS04725
gene id: 1286171:EAL2_RS04725
uniprot id: W8T3B0
names: Function
names: Similarity
messages: Belongs to the PyrI family.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

1286171:EAL2 RS03935
gene id: 1286171:EAL2_RS03935
uniprot id: W8T5E7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1286171:EAL2 RS05285
gene id: 1286171:EAL2_RS05285
uniprot id: W8U604
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1286171:EAL2 RS01540
gene id: 1286171:EAL2_RS01540
uniprot id: W8U3T3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

1286171:EAL2 RS00210
gene id: 1286171:EAL2_RS00210
uniprot id: W8U325
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1286171:EAL2 RS04240
gene id: 1286171:EAL2_RS04240
uniprot id: W8U5F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease PrsW family.
messages: Cell membrane
messages: Membrane

1286171:EAL2 RS00800
gene id: 1286171:EAL2_RS00800
uniprot id: W8U3D1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1286171:EAL2 RS11745
gene id: 1286171:EAL2_RS11745
uniprot id: W8TNE7
names: Similarity
messages: Belongs to the peptidase S14 family.

1286171:EAL2 RS00490
gene id: 1286171:EAL2_RS00490
uniprot id: W8T129
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

1286171:EAL2 RS02195
gene id: 1286171:EAL2_RS02195
uniprot id: W8THV2
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

1286171:EAL2 RS08635
gene id: 1286171:EAL2_RS08635
uniprot id: W8TLG8
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1286171:EAL2 RS00705
gene id: 1286171:EAL2_RS00705
uniprot id: W8TH06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1286171:EAL2 RS13705
gene id: 1286171:EAL2_RS13705
uniprot id: W8TPN2
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS12475
gene id: 1286171:EAL2_RS12475
uniprot id: W8T7X3
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS04525
gene id: 1286171:EAL2_RS04525
uniprot id: W8U5J8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1286171:EAL2 RS02235
gene id: 1286171:EAL2_RS02235
uniprot id: W8T4J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1286171:EAL2 RS07845
gene id: 1286171:EAL2_RS07845
uniprot id: W8TGB4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1286171:EAL2 RS08020
gene id: 1286171:EAL2_RS08020
uniprot id: W8T7N3
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1286171:EAL2 RS09200
gene id: 1286171:EAL2_RS09200
uniprot id: W8TLV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1286171:EAL2 RS02125
gene id: 1286171:EAL2_RS02125
uniprot id: W8THT9
names: Function
messages: May be involved in the biosynthesis of molybdopterin.

1286171:EAL2 RS12325
gene id: 1286171:EAL2_RS12325
uniprot id: W8UAH4
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS05720
gene id: 1286171:EAL2_RS05720
uniprot id: W8U693
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1286171:EAL2 RS04440
gene id: 1286171:EAL2_RS04440
uniprot id: W8T5S1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1286171:EAL2 RS00640
gene id: 1286171:EAL2_RS00640
uniprot id: W8T3R8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

1286171:EAL2 RS10270
gene id: 1286171:EAL2_RS10270
uniprot id: W8T6J2
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1286171:EAL2 RS05765
gene id: 1286171:EAL2_RS05765
uniprot id: W8T6D8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

1286171:EAL2 RS07175
gene id: 1286171:EAL2_RS07175
uniprot id: W8T790
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1286171:EAL2 RS11265
gene id: 1286171:EAL2_RS11265
uniprot id: W8T9H8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

1286171:EAL2 RS01530
gene id: 1286171:EAL2_RS01530
uniprot id: W8T1M0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1286171:EAL2 RS06245
gene id: 1286171:EAL2_RS06245
uniprot id: W8U6J5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1286171:EAL2 RS14305
gene id: 1286171:EAL2_RS14305
uniprot id: W8TKE8
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1286171:EAL2 RS07775
gene id: 1286171:EAL2_RS07775
uniprot id: W8T516
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1286171:EAL2 RS00990
gene id: 1286171:EAL2_RS00990
uniprot id: W8T1D0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

1286171:EAL2 RS07180
gene id: 1286171:EAL2_RS07180
uniprot id: W8U770
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1286171:EAL2 RS12470
gene id: 1286171:EAL2_RS12470
uniprot id: W8TJ61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Membrane

1286171:EAL2 RS09070
gene id: 1286171:EAL2_RS09070
uniprot id: W8TLT8
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1286171:EAL2 RS01845
gene id: 1286171:EAL2_RS01845
uniprot id: W8TCZ7
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1286171:EAL2 RS03560
gene id: 1286171:EAL2_RS03560
uniprot id: W8TDV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

1286171:EAL2 RS09325
gene id: 1286171:EAL2_RS09325
uniprot id: W8T622
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS09930
gene id: 1286171:EAL2_RS09930
uniprot id: W8U8W5
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1286171:EAL2 RS04310
gene id: 1286171:EAL2_RS04310
uniprot id: W8U5G2
names: Similarity
messages: Belongs to the UPF0045 family.

1286171:EAL2 RS02025
gene id: 1286171:EAL2_RS02025
uniprot id: W8THS2
names: Similarity
messages: Belongs to the peptidase S41A family.

1286171:EAL2 RS01970
gene id: 1286171:EAL2_RS01970
uniprot id: W8U420
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

1286171:EAL2 RS06130
gene id: 1286171:EAL2_RS06130
uniprot id: W8TJY7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1286171:EAL2 RS12445
gene id: 1286171:EAL2_RS12445
uniprot id: W8TNT6
names: Similarity
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit G family.

1286171:EAL2 RS00710
gene id: 1286171:EAL2_RS00710
uniprot id: W8TCF3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1286171:EAL2 RS13550
gene id: 1286171:EAL2_RS13550
uniprot id: W8UB86
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1286171:EAL2 RS00020
gene id: 1286171:EAL2_RS00020
uniprot id: W8TGR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1286171:EAL2 RS07185
gene id: 1286171:EAL2_RS07185
uniprot id: W8TKM7
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1286171:EAL2 RS01520
gene id: 1286171:EAL2_RS01520
uniprot id: W8THF9
names: Similarity
messages: Belongs to the FlgM family.

1286171:EAL2 RS09465
gene id: 1286171:EAL2_RS09465
uniprot id: W8TLZ3
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

1286171:EAL2 RS06550
gene id: 1286171:EAL2_RS06550
uniprot id: W8T6V6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1286171:EAL2 RS10620
gene id: 1286171:EAL2_RS10620
uniprot id: W8THX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1286171:EAL2 RS04120
gene id: 1286171:EAL2_RS04120
uniprot id: W8TE62
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1286171:EAL2 RS07445
gene id: 1286171:EAL2_RS07445
uniprot id: W8T7D2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1286171:EAL2 RS06745
gene id: 1286171:EAL2_RS06745
uniprot id: W8T4J1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1286171:EAL2 RS08040
gene id: 1286171:EAL2_RS08040
uniprot id: W8T579
names: Similarity
messages: Belongs to the UPF0749 family.

1286171:EAL2 RS10425
gene id: 1286171:EAL2_RS10425
uniprot id: W8THT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
messages: Homodimer.
messages: Involved in phosphonate degradation.

1286171:EAL2 RS07920
gene id: 1286171:EAL2_RS07920
uniprot id: W8TGC9
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family. DapH subfamily.
messages: Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.

1286171:EAL2 RS00630
gene id: 1286171:EAL2_RS00630
uniprot id: W8TCD6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1286171:EAL2 RS09205
gene id: 1286171:EAL2_RS09205
uniprot id: W8TH57
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1286171:EAL2 RS14130
gene id: 1286171:EAL2_RS14130
uniprot id: W8TKB7
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1286171:EAL2 RS00970
gene id: 1286171:EAL2_RS00970
uniprot id: W8T3Y7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1286171:EAL2 RS13075
gene id: 1286171:EAL2_RS13075
uniprot id: W8UAY3
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

1286171:EAL2 RS08660
gene id: 1286171:EAL2_RS08660
uniprot id: W8TLH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1286171:EAL2 RS08405
gene id: 1286171:EAL2_RS08405
uniprot id: W8TGN2
names: Similarity
messages: Belongs to the thioredoxin family.

1286171:EAL2 RS07715
gene id: 1286171:EAL2_RS07715
uniprot id: W8TKV7
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS13480
gene id: 1286171:EAL2_RS13480
uniprot id: W8TPG8
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1286171:EAL2 RS07420
gene id: 1286171:EAL2_RS07420
uniprot id: W8T7C8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1286171:EAL2 RS08755
gene id: 1286171:EAL2_RS08755
uniprot id: W8TLJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1286171:EAL2 RS10375
gene id: 1286171:EAL2_RS10375
uniprot id: W8TMG1
names: Similarity
messages: Belongs to the ThiD family.

1286171:EAL2 RS01020
gene id: 1286171:EAL2_RS01020
uniprot id: W8T3Z7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1286171:EAL2 RS07145
gene id: 1286171:EAL2_RS07145
uniprot id: W8T4P6
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS04645
gene id: 1286171:EAL2_RS04645
uniprot id: W8TJ56
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1286171:EAL2 RS00815
gene id: 1286171:EAL2_RS00815
uniprot id: W8T195
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1286171:EAL2 RS07995
gene id: 1286171:EAL2_RS07995
uniprot id: W8T568
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1286171:EAL2 RS07685
gene id: 1286171:EAL2_RS07685
uniprot id: W8U7I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1286171:EAL2 RS10310
gene id: 1286171:EAL2_RS10310
uniprot id: W8TME5
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

1286171:EAL2 RS08710
gene id: 1286171:EAL2_RS08710
uniprot id: W8TLI3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1286171:EAL2 RS01415
gene id: 1286171:EAL2_RS01415
uniprot id: W8U3N3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1286171:EAL2 RS06560
gene id: 1286171:EAL2_RS06560
uniprot id: W8TK86
names: Similarity
messages: Belongs to the ribF family.

1286171:EAL2 RS01735
gene id: 1286171:EAL2_RS01735
uniprot id: W8U3Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1286171:EAL2 RS02145
gene id: 1286171:EAL2_RS02145
uniprot id: W8THU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1286171:EAL2 RS04675
gene id: 1286171:EAL2_RS04675
uniprot id: W8T3A2
names: Similarity
messages: Belongs to the asparaginase 1 family.

1286171:EAL2 RS08160
gene id: 1286171:EAL2_RS08160
uniprot id: W8U7T0
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1286171:EAL2 RS14835
gene id: 1286171:EAL2_RS14835
uniprot id: W8U8K5
names: Similarity
messages: Belongs to the peptidase S8 family.

1286171:EAL2 RS13490
gene id: 1286171:EAL2_RS13490
uniprot id: W8T8K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

1286171:EAL2 RS05260
gene id: 1286171:EAL2_RS05260
uniprot id: W8U5Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1286171:EAL2 RS01300
gene id: 1286171:EAL2_RS01300
uniprot id: W8THA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1286171:EAL2 RS01675
gene id: 1286171:EAL2_RS01675
uniprot id: W8T1R0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1286171:EAL2 RS13160
gene id: 1286171:EAL2_RS13160
uniprot id: W8TP95
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1286171:EAL2 RS12340
gene id: 1286171:EAL2_RS12340
uniprot id: W8T7U0
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1286171:EAL2 RS10385
gene id: 1286171:EAL2_RS10385
uniprot id: W8T6M0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1286171:EAL2 RS11335
gene id: 1286171:EAL2_RS11335
uniprot id: W8T9J2
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1286171:EAL2 RS02940
gene id: 1286171:EAL2_RS02940
uniprot id: W8T4V0
names: Similarity
messages: Belongs to the peptidase S14 family.

1286171:EAL2 RS01325
gene id: 1286171:EAL2_RS01325
uniprot id: W8THB0
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

1286171:EAL2 RS12440
gene id: 1286171:EAL2_RS12440
uniprot id: W8UAJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1286171:EAL2 RS01835
gene id: 1286171:EAL2_RS01835
uniprot id: W8U3Z9
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1286171:EAL2 RS07625
gene id: 1286171:EAL2_RS07625
uniprot id: W8TG70
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

1286171:EAL2 RS13595
gene id: 1286171:EAL2_RS13595
uniprot id: W8TB13
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

1286171:EAL2 RS10950
gene id: 1286171:EAL2_RS10950
uniprot id: W8U9G4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1286171:EAL2 RS02215
gene id: 1286171:EAL2_RS02215
uniprot id: W8U470
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

1286171:EAL2 RS11160
gene id: 1286171:EAL2_RS11160
uniprot id: W8T737
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1286171:EAL2 RS10055
gene id: 1286171:EAL2_RS10055
uniprot id: W8T6E7
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1286171:EAL2 RS08410
gene id: 1286171:EAL2_RS08410
uniprot id: W8T5G6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1286171:EAL2 RS10415
gene id: 1286171:EAL2_RS10415
uniprot id: W8U967
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

1286171:EAL2 RS08510
gene id: 1286171:EAL2_RS08510
uniprot id: W8TLD9
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1286171:EAL2 RS06925
gene id: 1286171:EAL2_RS06925
uniprot id: W8T749
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1286171:EAL2 RS05915
gene id: 1286171:EAL2_RS05915
uniprot id: W8T6H0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1286171:EAL2 RS07440
gene id: 1286171:EAL2_RS07440
uniprot id: W8T4U8
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1286171:EAL2 RS04720
gene id: 1286171:EAL2_RS04720
uniprot id: W8TEK5
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1286171:EAL2 RS10530
gene id: 1286171:EAL2_RS10530
uniprot id: W8T6Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1286171:EAL2 RS09105
gene id: 1286171:EAL2_RS09105
uniprot id: W8T5Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

1286171:EAL2 RS12775
gene id: 1286171:EAL2_RS12775
uniprot id: W8TAF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1286171:EAL2 RS01320
gene id: 1286171:EAL2_RS01320
uniprot id: W8U3L2
names: Similarity
messages: Belongs to the Fur family.

1286171:EAL2 RS14190
gene id: 1286171:EAL2_RS14190
uniprot id: W8TBI0
names: Similarity
messages: Belongs to the peptidase S58 family.

1286171:EAL2 RS13630
gene id: 1286171:EAL2_RS13630
uniprot id: W8TPL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1286171:EAL2 RS08010
gene id: 1286171:EAL2_RS08010
uniprot id: W8TGF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1286171:EAL2 RS03340
gene id: 1286171:EAL2_RS03340
uniprot id: W8T2I6
names: Similarity
messages: Belongs to the ParB family.

1286171:EAL2 RS07130
gene id: 1286171:EAL2_RS07130
uniprot id: W8U761
names: Similarity
messages: Belongs to the NDK family.

1286171:EAL2 RS10685
gene id: 1286171:EAL2_RS10685
uniprot id: W8T966
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

1286171:EAL2 RS07220
gene id: 1286171:EAL2_RS07220
uniprot id: W8T4Q7
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS10775
gene id: 1286171:EAL2_RS10775
uniprot id: W8TI04
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1286171:EAL2 RS05815
gene id: 1286171:EAL2_RS05815
uniprot id: W8T6E8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1286171:EAL2 RS09615
gene id: 1286171:EAL2_RS09615
uniprot id: W8THD3
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS00840
gene id: 1286171:EAL2_RS00840
uniprot id: W8T1A1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1286171:EAL2 RS09755
gene id: 1286171:EAL2_RS09755
uniprot id: W8THF8
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1286171:EAL2 RS09330
gene id: 1286171:EAL2_RS09330
uniprot id: W8T8J1
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS12205
gene id: 1286171:EAL2_RS12205
uniprot id: W8TA48
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1286171:EAL2 RS12460
gene id: 1286171:EAL2_RS12460
uniprot id: W8UAK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
messages: Membrane

1286171:EAL2 RS04670
gene id: 1286171:EAL2_RS04670
uniprot id: W8TEJ7
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1286171:EAL2 RS05025
gene id: 1286171:EAL2_RS05025
uniprot id: W8U5V1
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1286171:EAL2 RS04015
gene id: 1286171:EAL2_RS04015
uniprot id: W8U567
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1286171:EAL2 RS05715
gene id: 1286171:EAL2_RS05715
uniprot id: W8T6C4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1286171:EAL2 RS00445
gene id: 1286171:EAL2_RS00445
uniprot id: W8T3M2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

1286171:EAL2 RS02375
gene id: 1286171:EAL2_RS02375
uniprot id: W8TD96
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1286171:EAL2 RS06565
gene id: 1286171:EAL2_RS06565
uniprot id: W8TFK4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1286171:EAL2 RS00900
gene id: 1286171:EAL2_RS00900
uniprot id: W8U3F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1286171:EAL2 RS01900
gene id: 1286171:EAL2_RS01900
uniprot id: W8T1U7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1286171:EAL2 RS07210
gene id: 1286171:EAL2_RS07210
uniprot id: W8TKN2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1286171:EAL2 RS06275
gene id: 1286171:EAL2_RS06275
uniprot id: W8TK23
names: Similarity
messages: Belongs to the Fur family.

1286171:EAL2 RS12370
gene id: 1286171:EAL2_RS12370
uniprot id: W8TA77
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1286171:EAL2 RS12480
gene id: 1286171:EAL2_RS12480
uniprot id: W8TAA3
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS07860
gene id: 1286171:EAL2_RS07860
uniprot id: W8U7L9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1286171:EAL2 RS00395
gene id: 1286171:EAL2_RS00395
uniprot id: W8T3L1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1286171:EAL2 RS10275
gene id: 1286171:EAL2_RS10275
uniprot id: W8T8Z2
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1286171:EAL2 RS06225
gene id: 1286171:EAL2_RS06225
uniprot id: W8TK11
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

1286171:EAL2 RS14290
gene id: 1286171:EAL2_RS14290
uniprot id: W8TBJ4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1286171:EAL2 RS07780
gene id: 1286171:EAL2_RS07780
uniprot id: W8T7I3
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1286171:EAL2 RS07385
gene id: 1286171:EAL2_RS07385
uniprot id: W8TG25
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

1286171:EAL2 RS03710
gene id: 1286171:EAL2_RS03710
uniprot id: W8TDY3
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1286171:EAL2 RS07170
gene id: 1286171:EAL2_RS07170
uniprot id: W8T4P9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1286171:EAL2 RS01825
gene id: 1286171:EAL2_RS01825
uniprot id: W8T1T5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1286171:EAL2 RS01885
gene id: 1286171:EAL2_RS01885
uniprot id: W8U409
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1286171:EAL2 RS06835
gene id: 1286171:EAL2_RS06835
uniprot id: W8TKG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1286171:EAL2 RS04530
gene id: 1286171:EAL2_RS04530
uniprot id: W8TJ34
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1286171:EAL2 RS01795
gene id: 1286171:EAL2_RS01795
uniprot id: W8TCY8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1286171:EAL2 RS12905
gene id: 1286171:EAL2_RS12905
uniprot id: W8TP32
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1286171:EAL2 RS02090
gene id: 1286171:EAL2_RS02090
uniprot id: W8U446
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1286171:EAL2 RS11385
gene id: 1286171:EAL2_RS11385
uniprot id: W8T792
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1286171:EAL2 RS04810
gene id: 1286171:EAL2_RS04810
uniprot id: W8U5Q4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1286171:EAL2 RS14670
gene id: 1286171:EAL2_RS14670
uniprot id: W8TC59
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1286171:EAL2 RS07480
gene id: 1286171:EAL2_RS07480
uniprot id: W8TKR8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1286171:EAL2 RS09210
gene id: 1286171:EAL2_RS09210
uniprot id: W8T608
names: Similarity
messages: Belongs to the class-I fumarase family.

1286171:EAL2 RS09020
gene id: 1286171:EAL2_RS09020
uniprot id: W8TLQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1286171:EAL2 RS03565
gene id: 1286171:EAL2_RS03565
uniprot id: W8T2N3
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1286171:EAL2 RS13810
gene id: 1286171:EAL2_RS13810
uniprot id: W8T8T1
names: Subcellular Location Annotation
messages: Cytoplasm

1286171:EAL2 RS03470
gene id: 1286171:EAL2_RS03470
uniprot id: W8T544
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS08265
gene id: 1286171:EAL2_RS08265
uniprot id: W8TL82
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

1286171:EAL2 RS05770
gene id: 1286171:EAL2_RS05770
uniprot id: W8U6A4
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

1286171:EAL2 RS06195
gene id: 1286171:EAL2_RS06195
uniprot id: W8U6I6
names: Similarity
messages: Belongs to the UPF0102 family.

1286171:EAL2 RS02610
gene id: 1286171:EAL2_RS02610
uniprot id: W8TDC9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1286171:EAL2 RS07100
gene id: 1286171:EAL2_RS07100
uniprot id: W8T778
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1286171:EAL2 RS04990
gene id: 1286171:EAL2_RS04990
uniprot id: W8T3F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1286171:EAL2 RS10560
gene id: 1286171:EAL2_RS10560
uniprot id: W8T944
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1286171:EAL2 RS00735
gene id: 1286171:EAL2_RS00735
uniprot id: W8TCF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1286171:EAL2 RS07725
gene id: 1286171:EAL2_RS07725
uniprot id: W8T504
names: Similarity
messages: Belongs to the FBPase class 3 family.

1286171:EAL2 RS06830
gene id: 1286171:EAL2_RS06830
uniprot id: W8U707
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1286171:EAL2 RS10650
gene id: 1286171:EAL2_RS10650
uniprot id: W8T6S7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

1286171:EAL2 RS12690
gene id: 1286171:EAL2_RS12690
uniprot id: W8TJA6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1286171:EAL2 RS11150
gene id: 1286171:EAL2_RS11150
uniprot id: W8TMY4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1286171:EAL2 RS02080
gene id: 1286171:EAL2_RS02080
uniprot id: W8T1X4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1286171:EAL2 RS10040
gene id: 1286171:EAL2_RS10040
uniprot id: W8U8Y8
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

1286171:EAL2 RS08360
gene id: 1286171:EAL2_RS08360
uniprot id: W8TGM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1286171:EAL2 RS06630
gene id: 1286171:EAL2_RS06630
uniprot id: W8U6X5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1286171:EAL2 RS06160
gene id: 1286171:EAL2_RS06160
uniprot id: W8TFC8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1286171:EAL2 RS00725
gene id: 1286171:EAL2_RS00725
uniprot id: W8U3B2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1286171:EAL2 RS04465
gene id: 1286171:EAL2_RS04465
uniprot id: W8T5S4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1286171:EAL2 RS05080
gene id: 1286171:EAL2_RS05080
uniprot id: W8TJD0
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1286171:EAL2 RS09585
gene id: 1286171:EAL2_RS09585
uniprot id: W8TM11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1286171:EAL2 RS05840
gene id: 1286171:EAL2_RS05840
uniprot id: W8T6F3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1286171:EAL2 RS12860
gene id: 1286171:EAL2_RS12860
uniprot id: W8TP22
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS07140
gene id: 1286171:EAL2_RS07140
uniprot id: W8TFX8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

1286171:EAL2 RS03480
gene id: 1286171:EAL2_RS03480
uniprot id: W8TIF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Membrane

1286171:EAL2 RS08825
gene id: 1286171:EAL2_RS08825
uniprot id: W8U875
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1286171:EAL2 RS14170
gene id: 1286171:EAL2_RS14170
uniprot id: W8UBT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1286171:EAL2 RS00110
gene id: 1286171:EAL2_RS00110
uniprot id: W8TGS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1286171:EAL2 RS08155
gene id: 1286171:EAL2_RS08155
uniprot id: W8T7R1
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1286171:EAL2 RS00825
gene id: 1286171:EAL2_RS00825
uniprot id: W8U3D6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1286171:EAL2 RS12000
gene id: 1286171:EAL2_RS12000
uniprot id: W8T7M6
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1286171:EAL2 RS08625
gene id: 1286171:EAL2_RS08625
uniprot id: W8T827
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1286171:EAL2 RS10585
gene id: 1286171:EAL2_RS10585
uniprot id: W8U995
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1286171:EAL2 RS13790
gene id: 1286171:EAL2_RS13790
uniprot id: W8TB65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate mutase GlmS subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.

1286171:EAL2 RS06720
gene id: 1286171:EAL2_RS06720
uniprot id: W8T4I6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1286171:EAL2 RS02220
gene id: 1286171:EAL2_RS02220
uniprot id: W8THV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Cytoplasm
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.

1286171:EAL2 RS03895
gene id: 1286171:EAL2_RS03895
uniprot id: W8TIN7
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

1286171:EAL2 RS08055
gene id: 1286171:EAL2_RS08055
uniprot id: W8T586
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1286171:EAL2 RS04735
gene id: 1286171:EAL2_RS04735
uniprot id: W8U5N8
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1286171:EAL2 RS04135
gene id: 1286171:EAL2_RS04135
uniprot id: W8U5B8
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1286171:EAL2 RS12535
gene id: 1286171:EAL2_RS12535
uniprot id: W8TNV8
names: Similarity
messages: Belongs to the peptidase S8 family.

1286171:EAL2 RS06545
gene id: 1286171:EAL2_RS06545
uniprot id: W8T4C6
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

1286171:EAL2 RS05030
gene id: 1286171:EAL2_RS05030
uniprot id: W8TJC1
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1286171:EAL2 RS14880
gene id: 1286171:EAL2_RS14880
uniprot id: W8THN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family.
messages: Cell membrane
messages: Membrane

1286171:EAL2 RS07905
gene id: 1286171:EAL2_RS07905
uniprot id: W8T7L2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1286171:EAL2 RS04410
gene id: 1286171:EAL2_RS04410
uniprot id: W8T355
names: Similarity
messages: Belongs to the HsdR family.

1286171:EAL2 RS11480
gene id: 1286171:EAL2_RS11480
uniprot id: W8TIG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

1286171:EAL2 RS04790
gene id: 1286171:EAL2_RS04790
uniprot id: W8TJ80
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1286171:EAL2 RS14035
gene id: 1286171:EAL2_RS14035
uniprot id: W8UBQ3
names: Similarity
messages: Belongs to the EamA transporter family.

1286171:EAL2 RS07790
gene id: 1286171:EAL2_RS07790
uniprot id: W8TA77
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1286171:EAL2 RS06575
gene id: 1286171:EAL2_RS06575
uniprot id: W8T6W1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1286171:EAL2 RS04040
gene id: 1286171:EAL2_RS04040
uniprot id: W8U574
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1286171:EAL2 RS01015
gene id: 1286171:EAL2_RS01015
uniprot id: W8T1D5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1286171:EAL2 RS03505
gene id: 1286171:EAL2_RS03505
uniprot id: W8TIF8
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1286171:EAL2 RS01490
gene id: 1286171:EAL2_RS01490
uniprot id: W8U3P9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1286171:EAL2 RS03700
gene id: 1286171:EAL2_RS03700
uniprot id: W8U501
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

1286171:EAL2 RS10875
gene id: 1286171:EAL2_RS10875
uniprot id: W8TMR4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1286171:EAL2 RS07405
gene id: 1286171:EAL2_RS07405
uniprot id: W8TKQ9
names: Subcellular Location Annotation
messages: Cytoplasm

1286171:EAL2 RS01800
gene id: 1286171:EAL2_RS01800
uniprot id: W8T1T0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1286171:EAL2 RS07740
gene id: 1286171:EAL2_RS07740
uniprot id: W8TKW3
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1286171:EAL2 RS01730
gene id: 1286171:EAL2_RS01730
uniprot id: W8T4D6
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1286171:EAL2 RS05710
gene id: 1286171:EAL2_RS05710
uniprot id: W8T3U4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1286171:EAL2 RS14785
gene id: 1286171:EAL2_RS14785
uniprot id: W8U716
names: Similarity
messages: Belongs to the universal stress protein A family.

1286171:EAL2 RS04945
gene id: 1286171:EAL2_RS04945
uniprot id: W8T600
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1286171:EAL2 RS03820
gene id: 1286171:EAL2_RS03820
uniprot id: W8U524
names: Similarity
messages: Belongs to the EamA transporter family.

1286171:EAL2 RS05055
gene id: 1286171:EAL2_RS05055
uniprot id: W8TJC5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1286171:EAL2 RS11005
gene id: 1286171:EAL2_RS11005
uniprot id: W8TMU3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1286171:EAL2 RS07110
gene id: 1286171:EAL2_RS07110
uniprot id: W8TKL6
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1286171:EAL2 RS07300
gene id: 1286171:EAL2_RS07300
uniprot id: W8U793
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1286171:EAL2 RS04680
gene id: 1286171:EAL2_RS04680
uniprot id: W8T5V7
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

1286171:EAL2 RS07365
gene id: 1286171:EAL2_RS07365
uniprot id: W8T4T3
names: Similarity
messages: Belongs to the RemA family.

1286171:EAL2 RS01295
gene id: 1286171:EAL2_RS01295
uniprot id: W8U3K8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1286171:EAL2 RS10690
gene id: 1286171:EAL2_RS10690
uniprot id: W8U9B1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1286171:EAL2 RS12320
gene id: 1286171:EAL2_RS12320
uniprot id: W8TA68
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

1286171:EAL2 RS06355
gene id: 1286171:EAL2_RS06355
uniprot id: W8T6R4
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1286171:EAL2 RS06055
gene id: 1286171:EAL2_RS06055
uniprot id: W8TJW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1286171:EAL2 RS07045
gene id: 1286171:EAL2_RS07045
uniprot id: W8T4N3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1286171:EAL2 RS10895
gene id: 1286171:EAL2_RS10895
uniprot id: W8U9F2
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1286171:EAL2 RS00115
gene id: 1286171:EAL2_RS00115
uniprot id: W8TC52
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1286171:EAL2 RS13310
gene id: 1286171:EAL2_RS13310
uniprot id: W8T8G1
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1286171:EAL2 RS07840
gene id: 1286171:EAL2_RS07840
uniprot id: W8TKY2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

1286171:EAL2 RS10825
gene id: 1286171:EAL2_RS10825
uniprot id: W8TMQ2
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1286171:EAL2 RS14415
gene id: 1286171:EAL2_RS14415
uniprot id: W8TBL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1286171:EAL2 RS01785
gene id: 1286171:EAL2_RS01785
uniprot id: W8U3Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1286171:EAL2 RS05730
gene id: 1286171:EAL2_RS05730
uniprot id: W8TF35
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1286171:EAL2 RS08145
gene id: 1286171:EAL2_RS08145
uniprot id: W8TL53
names: Similarity
messages: Belongs to the peptidase M18 family.

1286171:EAL2 RS14455
gene id: 1286171:EAL2_RS14455
uniprot id: W8TKH6
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1286171:EAL2 RS14145
gene id: 1286171:EAL2_RS14145
uniprot id: W8UBS8
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS11330
gene id: 1286171:EAL2_RS11330
uniprot id: W8T780
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1286171:EAL2 RS07770
gene id: 1286171:EAL2_RS07770
uniprot id: W8TG96
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1286171:EAL2 RS04930
gene id: 1286171:EAL2_RS04930
uniprot id: W8TJA4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1286171:EAL2 RS06140
gene id: 1286171:EAL2_RS06140
uniprot id: W8T440
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

1286171:EAL2 RS09650
gene id: 1286171:EAL2_RS09650
uniprot id: W8TM21
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS13465
gene id: 1286171:EAL2_RS13465
uniprot id: W8T8J9
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

1286171:EAL2 RS09985
gene id: 1286171:EAL2_RS09985
uniprot id: W8TM74
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.
messages: Dephosphorylates CpsD. Involved in the regulation of capsular polysaccharide biosynthesis.

1286171:EAL2 RS00870
gene id: 1286171:EAL2_RS00870
uniprot id: W8T3W9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1286171:EAL2 RS05990
gene id: 1286171:EAL2_RS05990
uniprot id: W8T6I5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1286171:EAL2 RS11460
gene id: 1286171:EAL2_RS11460
uniprot id: W8T7A9
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1286171:EAL2 RS10450
gene id: 1286171:EAL2_RS10450
uniprot id: W8TMH4
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS05755
gene id: 1286171:EAL2_RS05755
uniprot id: W8TF41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1286171:EAL2 RS01875
gene id: 1286171:EAL2_RS01875
uniprot id: W8T1U3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1286171:EAL2 RS02645
gene id: 1286171:EAL2_RS02645
uniprot id: W8T4Q4
names: Similarity
messages: Belongs to the peptidase S14 family.

1286171:EAL2 RS08175
gene id: 1286171:EAL2_RS08175
uniprot id: W8T5B2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1286171:EAL2 RS07000
gene id: 1286171:EAL2_RS07000
uniprot id: W8T760
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

1286171:EAL2 RS02890
gene id: 1286171:EAL2_RS02890
uniprot id: W8U4J4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1286171:EAL2 RS04880
gene id: 1286171:EAL2_RS04880
uniprot id: W8U5R9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1286171:EAL2 RS14090
gene id: 1286171:EAL2_RS14090
uniprot id: W8TBG4
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1286171:EAL2 RS08860
gene id: 1286171:EAL2_RS08860
uniprot id: W8T5R1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1286171:EAL2 RS08610
gene id: 1286171:EAL2_RS08610
uniprot id: W8TLG2
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1286171:EAL2 RS14325
gene id: 1286171:EAL2_RS14325
uniprot id: W8TQ39
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

1286171:EAL2 RS08940
gene id: 1286171:EAL2_RS08940
uniprot id: W8T899
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1286171:EAL2 RS12800
gene id: 1286171:EAL2_RS12800
uniprot id: W8TAG6
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1286171:EAL2 RS13050
gene id: 1286171:EAL2_RS13050
uniprot id: W8TP67
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS13190
gene id: 1286171:EAL2_RS13190
uniprot id: W8TJL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1286171:EAL2 RS09505
gene id: 1286171:EAL2_RS09505
uniprot id: W8T8M2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1286171:EAL2 RS13030
gene id: 1286171:EAL2_RS13030
uniprot id: W8TJH3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1286171:EAL2 RS06025
gene id: 1286171:EAL2_RS06025
uniprot id: W8U6F0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1286171:EAL2 RS11615
gene id: 1286171:EAL2_RS11615
uniprot id: W8TIN9
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

1286171:EAL2 RS05210
gene id: 1286171:EAL2_RS05210
uniprot id: W8U5Y6
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1286171:EAL2 RS07260
gene id: 1286171:EAL2_RS07260
uniprot id: W8TKN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1286171:EAL2 RS04620
gene id: 1286171:EAL2_RS04620
uniprot id: W8TJ51
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1286171:EAL2 RS05020
gene id: 1286171:EAL2_RS05020
uniprot id: W8T3G0
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1286171:EAL2 RS07855
gene id: 1286171:EAL2_RS07855
uniprot id: W8T7K1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1286171:EAL2 RS04115
gene id: 1286171:EAL2_RS04115
uniprot id: W8TIT6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1286171:EAL2 RS09890
gene id: 1286171:EAL2_RS09890
uniprot id: W8THI1
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS01455
gene id: 1286171:EAL2_RS01455
uniprot id: W8T1I2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1286171:EAL2 RS08260
gene id: 1286171:EAL2_RS08260
uniprot id: W8U7V0
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS00610
gene id: 1286171:EAL2_RS00610
uniprot id: W8T155
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1286171:EAL2 RS05250
gene id: 1286171:EAL2_RS05250
uniprot id: W8T3K3
names: Similarity
messages: Belongs to the UPF0749 family.

1286171:EAL2 RS08130
gene id: 1286171:EAL2_RS08130
uniprot id: W8T5A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

1286171:EAL2 RS10835
gene id: 1286171:EAL2_RS10835
uniprot id: W8T6W5
names: Similarity
messages: Belongs to the UPF0251 family.

1286171:EAL2 RS09115
gene id: 1286171:EAL2_RS09115
uniprot id: W8U8F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

1286171:EAL2 RS06605
gene id: 1286171:EAL2_RS06605
uniprot id: W8U6V8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1286171:EAL2 RS06815
gene id: 1286171:EAL2_RS06815
uniprot id: W8TFR8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

1286171:EAL2 RS06440
gene id: 1286171:EAL2_RS06440
uniprot id: W8TK60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1286171:EAL2 RS05215
gene id: 1286171:EAL2_RS05215
uniprot id: W8TJE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1286171:EAL2 RS12695
gene id: 1286171:EAL2_RS12695
uniprot id: W8T826
names: Similarity
messages: Belongs to the TrpC family.

1286171:EAL2 RS01410
gene id: 1286171:EAL2_RS01410
uniprot id: W8T449
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS05065
gene id: 1286171:EAL2_RS05065
uniprot id: W8T3H1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1286171:EAL2 RS12500
gene id: 1286171:EAL2_RS12500
uniprot id: W8T7X9
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1286171:EAL2 RS05275
gene id: 1286171:EAL2_RS05275
uniprot id: W8T3K8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1286171:EAL2 RS03435
gene id: 1286171:EAL2_RS03435
uniprot id: W8TDS7
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

1286171:EAL2 RS04875
gene id: 1286171:EAL2_RS04875
uniprot id: W8T5Y6
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1286171:EAL2 RS13010
gene id: 1286171:EAL2_RS13010
uniprot id: W8TJG7
names: Similarity
messages: Belongs to the DSD1 family.

1286171:EAL2 RS04745
gene id: 1286171:EAL2_RS04745
uniprot id: W8TEL1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

1286171:EAL2 RS01040
gene id: 1286171:EAL2_RS01040
uniprot id: W8T1D9
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS07590
gene id: 1286171:EAL2_RS07590
uniprot id: W8T7F1
names: Similarity
messages: Belongs to the archease family.

1286171:EAL2 RS10510
gene id: 1286171:EAL2_RS10510
uniprot id: W8T934
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1286171:EAL2 RS00785
gene id: 1286171:EAL2_RS00785
uniprot id: W8TCG4
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1286171:EAL2 RS00880
gene id: 1286171:EAL2_RS00880
uniprot id: W8TH39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1286171:EAL2 RS04805
gene id: 1286171:EAL2_RS04805
uniprot id: W8T5X5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1286171:EAL2 RS07710
gene id: 1286171:EAL2_RS07710
uniprot id: W8U7I8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

1286171:EAL2 RS03775
gene id: 1286171:EAL2_RS03775
uniprot id: W8TIL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1286171:EAL2 RS05975
gene id: 1286171:EAL2_RS05975
uniprot id: W8TJV0
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1286171:EAL2 RS04505
gene id: 1286171:EAL2_RS04505
uniprot id: W8TJ29
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1286171:EAL2 RS09485
gene id: 1286171:EAL2_RS09485
uniprot id: W8T8M0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

1286171:EAL2 RS14410
gene id: 1286171:EAL2_RS14410
uniprot id: W8T988
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

1286171:EAL2 RS01500
gene id: 1286171:EAL2_RS01500
uniprot id: W8TCT3
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

1286171:EAL2 RS04170
gene id: 1286171:EAL2_RS04170
uniprot id: W8T316
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1286171:EAL2 RS06445
gene id: 1286171:EAL2_RS06445
uniprot id: W8TFI2
names: Similarity
messages: Belongs to the glutamine synthetase family.

1286171:EAL2 RS04305
gene id: 1286171:EAL2_RS04305
uniprot id: W8T5Q1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1286171:EAL2 RS05705
gene id: 1286171:EAL2_RS05705
uniprot id: W8TF29
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1286171:EAL2 RS06030
gene id: 1286171:EAL2_RS06030
uniprot id: W8TJW1
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1286171:EAL2 RS01910
gene id: 1286171:EAL2_RS01910
uniprot id: W8U411
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1286171:EAL2 RS03730
gene id: 1286171:EAL2_RS03730
uniprot id: W8TIK0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1286171:EAL2 RS02930
gene id: 1286171:EAL2_RS02930
uniprot id: W8TDI7
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1286171:EAL2 RS04740
gene id: 1286171:EAL2_RS04740
uniprot id: W8TJ72
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

1286171:EAL2 RS01790
gene id: 1286171:EAL2_RS01790
uniprot id: W8THN4
names: Similarity
messages: Belongs to the FBPase class 2 family.

1286171:EAL2 RS10400
gene id: 1286171:EAL2_RS10400
uniprot id: W8TMG4
names: Similarity
messages: Belongs to the UPF0473 family.

1286171:EAL2 RS07340
gene id: 1286171:EAL2_RS07340
uniprot id: W8T4S9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1286171:EAL2 RS11405
gene id: 1286171:EAL2_RS11405
uniprot id: W8TIE9
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

1286171:EAL2 RS08730
gene id: 1286171:EAL2_RS08730
uniprot id: W8TLI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1286171:EAL2 RS04070
gene id: 1286171:EAL2_RS04070
uniprot id: W8TE55
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1286171:EAL2 RS13720
gene id: 1286171:EAL2_RS13720
uniprot id: W8TB45
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1286171:EAL2 RS09495
gene id: 1286171:EAL2_RS09495
uniprot id: W8THB2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1286171:EAL2 RS10850
gene id: 1286171:EAL2_RS10850
uniprot id: W8TMQ7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1286171:EAL2 RS07755
gene id: 1286171:EAL2_RS07755
uniprot id: W8T7H8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

1286171:EAL2 RS07395
gene id: 1286171:EAL2_RS07395
uniprot id: W8T7C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1286171:EAL2 RS08340
gene id: 1286171:EAL2_RS08340
uniprot id: W8TGL4
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

1286171:EAL2 RS06990
gene id: 1286171:EAL2_RS06990
uniprot id: W8TFV1
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS05900
gene id: 1286171:EAL2_RS05900
uniprot id: W8TF72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

1286171:EAL2 RS07915
gene id: 1286171:EAL2_RS07915
uniprot id: W8TL02
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1286171:EAL2 RS05845
gene id: 1286171:EAL2_RS05845
uniprot id: W8U6B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1286171:EAL2 RS13585
gene id: 1286171:EAL2_RS13585
uniprot id: W8TJW3
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

1286171:EAL2 RS05870
gene id: 1286171:EAL2_RS05870
uniprot id: W8TJS4
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1286171:EAL2 RS00565
gene id: 1286171:EAL2_RS00565
uniprot id: W8T3Q1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1286171:EAL2 RS00780
gene id: 1286171:EAL2_RS00780
uniprot id: W8TH20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1286171:EAL2 RS03425
gene id: 1286171:EAL2_RS03425
uniprot id: W8U4U7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1286171:EAL2 RS07060
gene id: 1286171:EAL2_RS07060
uniprot id: W8TKK5
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1286171:EAL2 RS05455
gene id: 1286171:EAL2_RS05455
uniprot id: W8TJI2
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1286171:EAL2 RS02570
gene id: 1286171:EAL2_RS02570
uniprot id: W8T249
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

1286171:EAL2 RS06045
gene id: 1286171:EAL2_RS06045
uniprot id: W8T6J7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1286171:EAL2 RS00770
gene id: 1286171:EAL2_RS00770
uniprot id: W8T3U7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1286171:EAL2 RS13315
gene id: 1286171:EAL2_RS13315
uniprot id: W8TAU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

1286171:EAL2 RS06520
gene id: 1286171:EAL2_RS06520
uniprot id: W8T4C0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1286171:EAL2 RS07825
gene id: 1286171:EAL2_RS07825
uniprot id: W8T526
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1286171:EAL2 RS07250
gene id: 1286171:EAL2_RS07250
uniprot id: W8T7A4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm

1286171:EAL2 RS07750
gene id: 1286171:EAL2_RS07750
uniprot id: W8T510
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1286171:EAL2 RS05180
gene id: 1286171:EAL2_RS05180
uniprot id: W8T635
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1286171:EAL2 RS02200
gene id: 1286171:EAL2_RS02200
uniprot id: W8TD68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1286171:EAL2 RS01710
gene id: 1286171:EAL2_RS01710
uniprot id: W8U3X8
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

1286171:EAL2 RS10480
gene id: 1286171:EAL2_RS10480
uniprot id: W8THU3
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1286171:EAL2 RS12645
gene id: 1286171:EAL2_RS12645
uniprot id: W8TAD3
names: Similarity
messages: Belongs to the Fur family.

1286171:EAL2 RS13650
gene id: 1286171:EAL2_RS13650
uniprot id: W8UBB4
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1286171:EAL2 RS06600
gene id: 1286171:EAL2_RS06600
uniprot id: W8T6Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1286171:EAL2 RS05970
gene id: 1286171:EAL2_RS05970
uniprot id: W8U6E1
names: Similarity
messages: Belongs to the asp23 family.

1286171:EAL2 RS00795
gene id: 1286171:EAL2_RS00795
uniprot id: W8T3V3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1286171:EAL2 RS00875
gene id: 1286171:EAL2_RS00875
uniprot id: W8U3E8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1286171:EAL2 RS08210
gene id: 1286171:EAL2_RS08210
uniprot id: W8U7U1
names: Subcellular Location Annotation
messages: Membrane

1286171:EAL2 RS03545
gene id: 1286171:EAL2_RS03545
uniprot id: W8T560
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1286171:EAL2 RS08615
gene id: 1286171:EAL2_RS08615
uniprot id: W8TGS2
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1286171:EAL2 RS00590
gene id: 1286171:EAL2_RS00590
uniprot id: W8T3Q6
names: Similarity
messages: Belongs to the ycf81 family.

1286171:EAL2 RS10345
gene id: 1286171:EAL2_RS10345
uniprot id: W8T902
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1286171:EAL2 RS14515
gene id: 1286171:EAL2_RS14515
uniprot id: W8TKI6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1286171:EAL2 RS10430
gene id: 1286171:EAL2_RS10430
uniprot id: W8T6N0
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.