1285583:CCASEI RS10090
gene id: 1285583:CCASEI_RS10090
uniprot id: W5XVA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1285583:CCASEI RS02465
gene id: 1285583:CCASEI_RS02465
uniprot id: W5XQA6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1285583:CCASEI RS01985
gene id: 1285583:CCASEI_RS01985
uniprot id: W5XQM6
names: Subcellular Location Annotation
messages: Cytoplasm

1285583:CCASEI RS11530
gene id: 1285583:CCASEI_RS11530
uniprot id: W5Y320
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm

1285583:CCASEI RS01920
gene id: 1285583:CCASEI_RS01920
uniprot id: W5XPV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1285583:CCASEI RS11420
gene id: 1285583:CCASEI_RS11420
uniprot id: W5XV61
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1285583:CCASEI RS04850
gene id: 1285583:CCASEI_RS04850
uniprot id: W5XRK0
names: Similarity
messages: Belongs to the glutamine synthetase family.

1285583:CCASEI RS05375
gene id: 1285583:CCASEI_RS05375
uniprot id: W5XRU2
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

1285583:CCASEI RS00785
gene id: 1285583:CCASEI_RS00785
uniprot id: W5XPB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

1285583:CCASEI RS11850
gene id: 1285583:CCASEI_RS11850
uniprot id: W5XW82
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

1285583:CCASEI RS00450
gene id: 1285583:CCASEI_RS00450
uniprot id: W5XPR9
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1285583:CCASEI RS03185
gene id: 1285583:CCASEI_RS03185
uniprot id: W5XYG4
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS11440
gene id: 1285583:CCASEI_RS11440
uniprot id: W5XV12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1285583:CCASEI RS05315
gene id: 1285583:CCASEI_RS05315
uniprot id: W5XSL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

1285583:CCASEI RS07065
gene id: 1285583:CCASEI_RS07065
uniprot id: W5XTH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1285583:CCASEI RS02755
gene id: 1285583:CCASEI_RS02755
uniprot id: W5XQF2
names: Similarity
messages: Belongs to the asp23 family.

1285583:CCASEI RS08760
gene id: 1285583:CCASEI_RS08760
uniprot id: W5XUD8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1285583:CCASEI RS04705
gene id: 1285583:CCASEI_RS04705
uniprot id: W5XRH1
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1285583:CCASEI RS01665
gene id: 1285583:CCASEI_RS01665
uniprot id: W5XQH4
names: Similarity
messages: Belongs to the catalase family.

1285583:CCASEI RS00475
gene id: 1285583:CCASEI_RS00475
uniprot id: W5XPS2
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

1285583:CCASEI RS05910
gene id: 1285583:CCASEI_RS05910
uniprot id: W5XS53
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1285583:CCASEI RS11995
gene id: 1285583:CCASEI_RS11995
uniprot id: W5XWD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1285583:CCASEI RS12880
gene id: 1285583:CCASEI_RS12880
uniprot id: W5XVT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1285583:CCASEI RS02690
gene id: 1285583:CCASEI_RS02690
uniprot id: W5XR36
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1285583:CCASEI RS07225
gene id: 1285583:CCASEI_RS07225
uniprot id: W5XSU1
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

1285583:CCASEI RS13015
gene id: 1285583:CCASEI_RS13015
uniprot id: W5Y3Q6
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1285583:CCASEI RS07850
gene id: 1285583:CCASEI_RS07850
uniprot id: W5XU01
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1285583:CCASEI RS13880
gene id: 1285583:CCASEI_RS13880
uniprot id: W5XXB9
names: Similarity
messages: Belongs to the PheA/TfdB FAD monooxygenase family.

1285583:CCASEI RS09700
gene id: 1285583:CCASEI_RS09700
uniprot id: W5XUZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1285583:CCASEI RS03240
gene id: 1285583:CCASEI_RS03240
uniprot id: W5XRF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1285583:CCASEI RS12210
gene id: 1285583:CCASEI_RS12210
uniprot id: W5XWG3
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1285583:CCASEI RS01700
gene id: 1285583:CCASEI_RS01700
uniprot id: W5XPW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1285583:CCASEI RS04065
gene id: 1285583:CCASEI_RS04065
uniprot id: W5XYZ8
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

1285583:CCASEI RS01150
gene id: 1285583:CCASEI_RS01150
uniprot id: W5XPE6
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS01685
gene id: 1285583:CCASEI_RS01685
uniprot id: W5XQL6
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

1285583:CCASEI RS04600
gene id: 1285583:CCASEI_RS04600
uniprot id: W5XS43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1285583:CCASEI RS04150
gene id: 1285583:CCASEI_RS04150
uniprot id: W5XR74
names: Similarity
messages: Belongs to the histone deacetylase family.

1285583:CCASEI RS12655
gene id: 1285583:CCASEI_RS12655
uniprot id: W5XVP2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

1285583:CCASEI RS06275
gene id: 1285583:CCASEI_RS06275
uniprot id: W5Y026
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS03270
gene id: 1285583:CCASEI_RS03270
uniprot id: W5XRA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1285583:CCASEI RS14440
gene id: 1285583:CCASEI_RS14440
uniprot id: W5XTF9
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1285583:CCASEI RS07230
gene id: 1285583:CCASEI_RS07230
uniprot id: W5XSY4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1285583:CCASEI RS00655
gene id: 1285583:CCASEI_RS00655
uniprot id: W5XP49
names: Similarity
messages: Belongs to the pirin family.

1285583:CCASEI RS11155
gene id: 1285583:CCASEI_RS11155
uniprot id: W5XV10
names: Similarity
messages: Belongs to the DapA family.

1285583:CCASEI RS01955
gene id: 1285583:CCASEI_RS01955
uniprot id: W5XQR5
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS14095
gene id: 1285583:CCASEI_RS14095
uniprot id: W5XWK0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1285583:CCASEI RS06210
gene id: 1285583:CCASEI_RS06210
uniprot id: W5XT15
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1285583:CCASEI RS12955
gene id: 1285583:CCASEI_RS12955
uniprot id: W5XVU8
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1285583:CCASEI RS04730
gene id: 1285583:CCASEI_RS04730
uniprot id: W5XRH1
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1285583:CCASEI RS05970
gene id: 1285583:CCASEI_RS05970
uniprot id: W5XZW4
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1285583:CCASEI RS12985
gene id: 1285583:CCASEI_RS12985
uniprot id: W5XW12
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1285583:CCASEI RS03590
gene id: 1285583:CCASEI_RS03590
uniprot id: W5XRN5
names: Similarity
messages: Belongs to the AccD/PCCB family.

1285583:CCASEI RS09995
gene id: 1285583:CCASEI_RS09995
uniprot id: W5XV44
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1285583:CCASEI RS12535
gene id: 1285583:CCASEI_RS12535
uniprot id: W5XVT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1285583:CCASEI RS11890
gene id: 1285583:CCASEI_RS11890
uniprot id: W5Y375
names: Similarity
messages: Belongs to the fructosamine kinase family.

1285583:CCASEI RS02470
gene id: 1285583:CCASEI_RS02470
uniprot id: W5XY37
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

1285583:CCASEI RS02100
gene id: 1285583:CCASEI_RS02100
uniprot id: W5XQ39
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1285583:CCASEI RS08595
gene id: 1285583:CCASEI_RS08595
uniprot id: W5XTJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1285583:CCASEI RS00805
gene id: 1285583:CCASEI_RS00805
uniprot id: W5XP80
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS13800
gene id: 1285583:CCASEI_RS13800
uniprot id: W5Y481
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1285583:CCASEI RS06415
gene id: 1285583:CCASEI_RS06415
uniprot id: W5XSK2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1285583:CCASEI RS04005
gene id: 1285583:CCASEI_RS04005
uniprot id: W5XR48
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1285583:CCASEI RS02810
gene id: 1285583:CCASEI_RS02810
uniprot id: W5XY97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1285583:CCASEI RS06180
gene id: 1285583:CCASEI_RS06180
uniprot id: W5XT38
names: Similarity
messages: Belongs to the ribF family.

1285583:CCASEI RS10140
gene id: 1285583:CCASEI_RS10140
uniprot id: W5Y288
names: Similarity
messages: Belongs to the FPG family.

1285583:CCASEI RS10000
gene id: 1285583:CCASEI_RS10000
uniprot id: W5XUA2
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1285583:CCASEI RS01120
gene id: 1285583:CCASEI_RS01120
uniprot id: W5XQ67
names: Similarity
messages: Belongs to the UPF0145 family.

1285583:CCASEI RS08470
gene id: 1285583:CCASEI_RS08470
uniprot id: W5XTG1
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1285583:CCASEI RS13875
gene id: 1285583:CCASEI_RS13875
uniprot id: W5Y499
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS07805
gene id: 1285583:CCASEI_RS07805
uniprot id: W5XTZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1285583:CCASEI RS06585
gene id: 1285583:CCASEI_RS06585
uniprot id: W5XSJ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1285583:CCASEI RS01010
gene id: 1285583:CCASEI_RS01010
uniprot id: W5XPG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1285583:CCASEI RS05240
gene id: 1285583:CCASEI_RS05240
uniprot id: W5XSK1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1285583:CCASEI RS02055
gene id: 1285583:CCASEI_RS02055
uniprot id: W5XXW1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1285583:CCASEI RS04640
gene id: 1285583:CCASEI_RS04640
uniprot id: W5XSB3
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

1285583:CCASEI RS03075
gene id: 1285583:CCASEI_RS03075
uniprot id: W5XQG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

1285583:CCASEI RS12185
gene id: 1285583:CCASEI_RS12185
uniprot id: W5XWF9
names: Caution
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lacks the conserved His residue that binds heme iron in the nitrobindin family.

1285583:CCASEI RS02495
gene id: 1285583:CCASEI_RS02495
uniprot id: W5XY41
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Could possibly oxidize fatty acids using specific components.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1285583:CCASEI RS07335
gene id: 1285583:CCASEI_RS07335
uniprot id: W5XT01
names: Similarity
messages: Belongs to the UPF0237 family.

1285583:CCASEI RS06985
gene id: 1285583:CCASEI_RS06985
uniprot id: W5XTK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1285583:CCASEI RS01575
gene id: 1285583:CCASEI_RS01575
uniprot id: W5XXN2
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1285583:CCASEI RS10405
gene id: 1285583:CCASEI_RS10405
uniprot id: W5Y2D3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1285583:CCASEI RS08980
gene id: 1285583:CCASEI_RS08980
uniprot id: W5Y1P0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1285583:CCASEI RS10915
gene id: 1285583:CCASEI_RS10915
uniprot id: W5XUQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1285583:CCASEI RS11610
gene id: 1285583:CCASEI_RS11610
uniprot id: W5XW73
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS03500
gene id: 1285583:CCASEI_RS03500
uniprot id: W5XQR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1285583:CCASEI RS02565
gene id: 1285583:CCASEI_RS02565
uniprot id: W5XQC3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1285583:CCASEI RS10985
gene id: 1285583:CCASEI_RS10985
uniprot id: W5XVP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1285583:CCASEI RS05205
gene id: 1285583:CCASEI_RS05205
uniprot id: W5XRR8
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS11360
gene id: 1285583:CCASEI_RS11360
uniprot id: W5XUZ6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1285583:CCASEI RS12915
gene id: 1285583:CCASEI_RS12915
uniprot id: W5Y3P0
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1285583:CCASEI RS10010
gene id: 1285583:CCASEI_RS10010
uniprot id: W5Y266
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1285583:CCASEI RS01340
gene id: 1285583:CCASEI_RS01340
uniprot id: W5XQE5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

1285583:CCASEI RS09240
gene id: 1285583:CCASEI_RS09240
uniprot id: W5Y1T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1285583:CCASEI RS10245
gene id: 1285583:CCASEI_RS10245
uniprot id: W5Y2A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

1285583:CCASEI RS01495
gene id: 1285583:CCASEI_RS01495
uniprot id: W5XQF1
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS08635
gene id: 1285583:CCASEI_RS08635
uniprot id: W5XUG6
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS04245
gene id: 1285583:CCASEI_RS04245
uniprot id: W5XRY1
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1285583:CCASEI RS12700
gene id: 1285583:CCASEI_RS12700
uniprot id: W5XWM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

1285583:CCASEI RS05750
gene id: 1285583:CCASEI_RS05750
uniprot id: W5XSU7
names: Similarity
messages: Belongs to the CutC family.

1285583:CCASEI RS05720
gene id: 1285583:CCASEI_RS05720
uniprot id: W5XZR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1285583:CCASEI RS05890
gene id: 1285583:CCASEI_RS05890
uniprot id: W5XS45
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1285583:CCASEI RS02965
gene id: 1285583:CCASEI_RS02965
uniprot id: W5XR90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1285583:CCASEI RS13715
gene id: 1285583:CCASEI_RS13715
uniprot id: W5XWF6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1285583:CCASEI RS03470
gene id: 1285583:CCASEI_RS03470
uniprot id: W5XRE2
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1285583:CCASEI RS03725
gene id: 1285583:CCASEI_RS03725
uniprot id: W5XR04
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1285583:CCASEI RS00025
gene id: 1285583:CCASEI_RS00025
uniprot id: W5XNV3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1285583:CCASEI RS04090
gene id: 1285583:CCASEI_RS04090
uniprot id: W5XZ03
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS01110
gene id: 1285583:CCASEI_RS01110
uniprot id: W5XXC3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1285583:CCASEI RS07885
gene id: 1285583:CCASEI_RS07885
uniprot id: W5XT56
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1285583:CCASEI RS04540
gene id: 1285583:CCASEI_RS04540
uniprot id: W5XRG0
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS05825
gene id: 1285583:CCASEI_RS05825
uniprot id: W5XSW0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1285583:CCASEI RS09885
gene id: 1285583:CCASEI_RS09885
uniprot id: W5Y246
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

1285583:CCASEI RS14100
gene id: 1285583:CCASEI_RS14100
uniprot id: W5XWR2
names: Similarity
messages: Belongs to the thioredoxin family.

1285583:CCASEI RS07510
gene id: 1285583:CCASEI_RS07510
uniprot id: W5XTU3
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1285583:CCASEI RS13400
gene id: 1285583:CCASEI_RS13400
uniprot id: W5XW24
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

1285583:CCASEI RS13545
gene id: 1285583:CCASEI_RS13545
uniprot id: W5Y425
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1285583:CCASEI RS02975
gene id: 1285583:CCASEI_RS02975
uniprot id: W5XQD9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1285583:CCASEI RS10875
gene id: 1285583:CCASEI_RS10875
uniprot id: W5XUV1
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1285583:CCASEI RS10600
gene id: 1285583:CCASEI_RS10600
uniprot id: W5XUI7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1285583:CCASEI RS02580
gene id: 1285583:CCASEI_RS02580
uniprot id: W5XR21
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS01000
gene id: 1285583:CCASEI_RS01000
uniprot id: W5XQ34
names: Function
names: Similarity
messages: Belongs to the AMP nucleosidase family.
messages: Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.

1285583:CCASEI RS03295
gene id: 1285583:CCASEI_RS03295
uniprot id: W5XRA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1285583:CCASEI RS12335
gene id: 1285583:CCASEI_RS12335
uniprot id: W5XWG2
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS02920
gene id: 1285583:CCASEI_RS02920
uniprot id: W5XR35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1285583:CCASEI RS07480
gene id: 1285583:CCASEI_RS07480
uniprot id: W5Y0R8
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1285583:CCASEI RS12605
gene id: 1285583:CCASEI_RS12605
uniprot id: W5XVN3
names: Similarity
messages: Belongs to the peptidase S13 family.

1285583:CCASEI RS12155
gene id: 1285583:CCASEI_RS12155
uniprot id: W5Y3A5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1285583:CCASEI RS09560
gene id: 1285583:CCASEI_RS09560
uniprot id: W5Y1Y7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1285583:CCASEI RS11045
gene id: 1285583:CCASEI_RS11045
uniprot id: W5XVQ5
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1285583:CCASEI RS10400
gene id: 1285583:CCASEI_RS10400
uniprot id: W5XUL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

1285583:CCASEI RS02345
gene id: 1285583:CCASEI_RS02345
uniprot id: W5XQY6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1285583:CCASEI RS06270
gene id: 1285583:CCASEI_RS06270
uniprot id: W5XSD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1285583:CCASEI RS02900
gene id: 1285583:CCASEI_RS02900
uniprot id: W5XQC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1285583:CCASEI RS06675
gene id: 1285583:CCASEI_RS06675
uniprot id: W5Y0C4
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1285583:CCASEI RS07275
gene id: 1285583:CCASEI_RS07275
uniprot id: W5XSV0
names: Similarity
messages: Belongs to the UPF0098 family.

1285583:CCASEI RS05880
gene id: 1285583:CCASEI_RS05880
uniprot id: W5XST9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1285583:CCASEI RS00155
gene id: 1285583:CCASEI_RS00155
uniprot id: W5XPN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1285583:CCASEI RS10830
gene id: 1285583:CCASEI_RS10830
uniprot id: W5Y2L3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1285583:CCASEI RS00600
gene id: 1285583:CCASEI_RS00600
uniprot id: W5XPU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1285583:CCASEI RS01670
gene id: 1285583:CCASEI_RS01670
uniprot id: W5XPR3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1285583:CCASEI RS05265
gene id: 1285583:CCASEI_RS05265
uniprot id: W5XSK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1285583:CCASEI RS05305
gene id: 1285583:CCASEI_RS05305
uniprot id: W5XRT4
names: Similarity
messages: Belongs to the asparagine synthetase family.

1285583:CCASEI RS12145
gene id: 1285583:CCASEI_RS12145
uniprot id: W5XVE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1285583:CCASEI RS06220
gene id: 1285583:CCASEI_RS06220
uniprot id: W5XSC0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1285583:CCASEI RS09925
gene id: 1285583:CCASEI_RS09925
uniprot id: W5XU91
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS03160
gene id: 1285583:CCASEI_RS03160
uniprot id: W5XYG1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1285583:CCASEI RS06190
gene id: 1285583:CCASEI_RS06190
uniprot id: W5XSB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1285583:CCASEI RS12010
gene id: 1285583:CCASEI_RS12010
uniprot id: W5XVK2
names: Similarity
messages: Belongs to the universal stress protein A family.

1285583:CCASEI RS02620
gene id: 1285583:CCASEI_RS02620
uniprot id: W5XR25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1285583:CCASEI RS07920
gene id: 1285583:CCASEI_RS07920
uniprot id: W5Y0Y8
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1285583:CCASEI RS05785
gene id: 1285583:CCASEI_RS05785
uniprot id: W5XS24
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1285583:CCASEI RS03325
gene id: 1285583:CCASEI_RS03325
uniprot id: W5XQM0
names: Similarity
messages: Belongs to the Dps family.

1285583:CCASEI RS12255
gene id: 1285583:CCASEI_RS12255
uniprot id: W5XWH0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1285583:CCASEI RS03120
gene id: 1285583:CCASEI_RS03120
uniprot id: W5XR71
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1285583:CCASEI RS11015
gene id: 1285583:CCASEI_RS11015
uniprot id: W5XVQ1
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1285583:CCASEI RS05820
gene id: 1285583:CCASEI_RS05820
uniprot id: W5XZT4
names: Similarity
messages: Belongs to the acylphosphatase family.

1285583:CCASEI RS08610
gene id: 1285583:CCASEI_RS08610
uniprot id: W5XUG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1285583:CCASEI RS11940
gene id: 1285583:CCASEI_RS11940
uniprot id: W5XWC8
names: Similarity
messages: Belongs to the PrpD family.

1285583:CCASEI RS07255
gene id: 1285583:CCASEI_RS07255
uniprot id: W5XSY9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1285583:CCASEI RS10055
gene id: 1285583:CCASEI_RS10055
uniprot id: W5XUG7
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1285583:CCASEI RS12435
gene id: 1285583:CCASEI_RS12435
uniprot id: W5XWH5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1285583:CCASEI RS03490
gene id: 1285583:CCASEI_RS03490
uniprot id: W5XRL3
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

1285583:CCASEI RS12450
gene id: 1285583:CCASEI_RS12450
uniprot id: W5Y3E7
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1285583:CCASEI RS02875
gene id: 1285583:CCASEI_RS02875
uniprot id: W5XQC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1285583:CCASEI RS13785
gene id: 1285583:CCASEI_RS13785
uniprot id: W5XXA0
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1285583:CCASEI RS08845
gene id: 1285583:CCASEI_RS08845
uniprot id: W5XTQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

1285583:CCASEI RS05220
gene id: 1285583:CCASEI_RS05220
uniprot id: W5XSF9
names: Similarity
messages: Belongs to the glutamine synthetase family.

1285583:CCASEI RS01165
gene id: 1285583:CCASEI_RS01165
uniprot id: W5XQ85
names: Similarity
messages: Belongs to the CmpA/NrtA family.

1285583:CCASEI RS05440
gene id: 1285583:CCASEI_RS05440
uniprot id: W5XZL4
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1285583:CCASEI RS01900
gene id: 1285583:CCASEI_RS01900
uniprot id: W5XQ03
names: Similarity
messages: Belongs to the Nudix hydrolase family. PCD1 subfamily.

1285583:CCASEI RS02005
gene id: 1285583:CCASEI_RS02005
uniprot id: W5XQS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1285583:CCASEI RS00015
gene id: 1285583:CCASEI_RS00015
uniprot id: W5XPL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1285583:CCASEI RS03310
gene id: 1285583:CCASEI_RS03310
uniprot id: W5XYI4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1285583:CCASEI RS09115
gene id: 1285583:CCASEI_RS09115
uniprot id: W5XTW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

1285583:CCASEI RS04485
gene id: 1285583:CCASEI_RS04485
uniprot id: W5XS21
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1285583:CCASEI RS07460
gene id: 1285583:CCASEI_RS07460
uniprot id: W5XTT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

1285583:CCASEI RS01555
gene id: 1285583:CCASEI_RS01555
uniprot id: W5XQF7
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS11885
gene id: 1285583:CCASEI_RS11885
uniprot id: W5XVH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1285583:CCASEI RS09030
gene id: 1285583:CCASEI_RS09030
uniprot id: W5XUM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

1285583:CCASEI RS01960
gene id: 1285583:CCASEI_RS01960
uniprot id: W5XQM2
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS06830
gene id: 1285583:CCASEI_RS06830
uniprot id: W5XTI4
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS02915
gene id: 1285583:CCASEI_RS02915
uniprot id: W5XR79
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1285583:CCASEI RS06805
gene id: 1285583:CCASEI_RS06805
uniprot id: W5XTI0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1285583:CCASEI RS05710
gene id: 1285583:CCASEI_RS05710
uniprot id: W5XS07
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1285583:CCASEI RS13855
gene id: 1285583:CCASEI_RS13855
uniprot id: W5XXB3
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

1285583:CCASEI RS01580
gene id: 1285583:CCASEI_RS01580
uniprot id: W5XQK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1285583:CCASEI RS13115
gene id: 1285583:CCASEI_RS13115
uniprot id: W5Y3S6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1285583:CCASEI RS12550
gene id: 1285583:CCASEI_RS12550
uniprot id: W5XWJ7
names: Similarity
messages: Belongs to the pantothenate synthetase family.

1285583:CCASEI RS01405
gene id: 1285583:CCASEI_RS01405
uniprot id: W5XPT0
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS03540
gene id: 1285583:CCASEI_RS03540
uniprot id: W5XRM5
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1285583:CCASEI RS07970
gene id: 1285583:CCASEI_RS07970
uniprot id: W5XTA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1285583:CCASEI RS06435
gene id: 1285583:CCASEI_RS06435
uniprot id: W5XSH6
names: Function
names: Similarity
names: Subunit
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.
messages: Homotrimer.

1285583:CCASEI RS05105
gene id: 1285583:CCASEI_RS05105
uniprot id: W5XZG4
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1285583:CCASEI RS07530
gene id: 1285583:CCASEI_RS07530
uniprot id: W5Y0S7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1285583:CCASEI RS06290
gene id: 1285583:CCASEI_RS06290
uniprot id: W5XSD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1285583:CCASEI RS08450
gene id: 1285583:CCASEI_RS08450
uniprot id: W5XTK4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1285583:CCASEI RS14085
gene id: 1285583:CCASEI_RS14085
uniprot id: W5XXG9
names: Similarity
messages: Belongs to the peptidase M1 family.

1285583:CCASEI RS05865
gene id: 1285583:CCASEI_RS05865
uniprot id: W5XS38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1285583:CCASEI RS10700
gene id: 1285583:CCASEI_RS10700
uniprot id: W5XUR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1285583:CCASEI RS07620
gene id: 1285583:CCASEI_RS07620
uniprot id: W5XT12
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1285583:CCASEI RS04795
gene id: 1285583:CCASEI_RS04795
uniprot id: W5XS82
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1285583:CCASEI RS02925
gene id: 1285583:CCASEI_RS02925
uniprot id: W5XQC8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1285583:CCASEI RS12830
gene id: 1285583:CCASEI_RS12830
uniprot id: W5XVS4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1285583:CCASEI RS12515
gene id: 1285583:CCASEI_RS12515
uniprot id: W5Y3G3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1285583:CCASEI RS02635
gene id: 1285583:CCASEI_RS02635
uniprot id: W5XY61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1285583:CCASEI RS02870
gene id: 1285583:CCASEI_RS02870
uniprot id: W5XR27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1285583:CCASEI RS02815
gene id: 1285583:CCASEI_RS02815
uniprot id: W5XR56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1285583:CCASEI RS02730
gene id: 1285583:CCASEI_RS02730
uniprot id: W5XQE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1285583:CCASEI RS12090
gene id: 1285583:CCASEI_RS12090
uniprot id: W5XVE0
names: Similarity
messages: Belongs to the CsoR family.

1285583:CCASEI RS11395
gene id: 1285583:CCASEI_RS11395
uniprot id: W5XV55
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1285583:CCASEI RS07770
gene id: 1285583:CCASEI_RS07770
uniprot id: W5XT72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1285583:CCASEI RS12785
gene id: 1285583:CCASEI_RS12785
uniprot id: W5XVY3
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1285583:CCASEI RS07195
gene id: 1285583:CCASEI_RS07195
uniprot id: W5XTJ7
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily.

1285583:CCASEI RS08500
gene id: 1285583:CCASEI_RS08500
uniprot id: W5XTL5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1285583:CCASEI RS03335
gene id: 1285583:CCASEI_RS03335
uniprot id: W5XYI9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1285583:CCASEI RS01890
gene id: 1285583:CCASEI_RS01890
uniprot id: W5XQL0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1285583:CCASEI RS00005
gene id: 1285583:CCASEI_RS00005
uniprot id: W5XWM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1285583:CCASEI RS06945
gene id: 1285583:CCASEI_RS06945
uniprot id: W5XSU0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1285583:CCASEI RS08425
gene id: 1285583:CCASEI_RS08425
uniprot id: W5XTJ9
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS13590
gene id: 1285583:CCASEI_RS13590
uniprot id: W5XWD2
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

1285583:CCASEI RS05620
gene id: 1285583:CCASEI_RS05620
uniprot id: W5XSS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1285583:CCASEI RS03065
gene id: 1285583:CCASEI_RS03065
uniprot id: W5XRB2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1285583:CCASEI RS09465
gene id: 1285583:CCASEI_RS09465
uniprot id: W5XUZ5
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1285583:CCASEI RS04815
gene id: 1285583:CCASEI_RS04815
uniprot id: W5XSE2
names: Similarity
messages: Belongs to the glutamine synthetase family.

1285583:CCASEI RS05010
gene id: 1285583:CCASEI_RS05010
uniprot id: W5XSC3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

1285583:CCASEI RS05540
gene id: 1285583:CCASEI_RS05540
uniprot id: W5XZN0
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS12870
gene id: 1285583:CCASEI_RS12870
uniprot id: W5XWR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1285583:CCASEI RS10050
gene id: 1285583:CCASEI_RS10050
uniprot id: W5XUB0
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1285583:CCASEI RS12100
gene id: 1285583:CCASEI_RS12100
uniprot id: W5Y399
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1285583:CCASEI RS02455
gene id: 1285583:CCASEI_RS02455
uniprot id: W5XQV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1285583:CCASEI RS08530
gene id: 1285583:CCASEI_RS08530
uniprot id: W5Y1B8
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1285583:CCASEI RS05465
gene id: 1285583:CCASEI_RS05465
uniprot id: W5XZL7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1285583:CCASEI RS09990
gene id: 1285583:CCASEI_RS09990
uniprot id: W5XV83
names: Similarity
messages: Belongs to the peptidase S1C family.

1285583:CCASEI RS05740
gene id: 1285583:CCASEI_RS05740
uniprot id: W5XS10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1285583:CCASEI RS12495
gene id: 1285583:CCASEI_RS12495
uniprot id: W5XWK6
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1285583:CCASEI RS13535
gene id: 1285583:CCASEI_RS13535
uniprot id: W5XW47
names: Similarity
messages: Belongs to the thioredoxin family.

1285583:CCASEI RS02350
gene id: 1285583:CCASEI_RS02350
uniprot id: W5XQU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

1285583:CCASEI RS06130
gene id: 1285583:CCASEI_RS06130
uniprot id: W5XT29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1285583:CCASEI RS08765
gene id: 1285583:CCASEI_RS08765
uniprot id: W5XTN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1285583:CCASEI RS13670
gene id: 1285583:CCASEI_RS13670
uniprot id: W5Y450
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

1285583:CCASEI RS07780
gene id: 1285583:CCASEI_RS07780
uniprot id: W5XTY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1285583:CCASEI RS06395
gene id: 1285583:CCASEI_RS06395
uniprot id: W5Y089
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1285583:CCASEI RS06150
gene id: 1285583:CCASEI_RS06150
uniprot id: W5Y001
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1285583:CCASEI RS08900
gene id: 1285583:CCASEI_RS08900
uniprot id: W5XTT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

1285583:CCASEI RS06540
gene id: 1285583:CCASEI_RS06540
uniprot id: W5XSM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1285583:CCASEI RS09045
gene id: 1285583:CCASEI_RS09045
uniprot id: W5XTZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1285583:CCASEI RS12125
gene id: 1285583:CCASEI_RS12125
uniprot id: W5Y3A1
names: Similarity
messages: Belongs to the cytochrome P450 family.

1285583:CCASEI RS05040
gene id: 1285583:CCASEI_RS05040
uniprot id: W5XRN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1285583:CCASEI RS13930
gene id: 1285583:CCASEI_RS13930
uniprot id: W5XXD0
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS04980
gene id: 1285583:CCASEI_RS04980
uniprot id: W5XSG1
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1285583:CCASEI RS02000
gene id: 1285583:CCASEI_RS02000
uniprot id: W5XXV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1285583:CCASEI RS07475
gene id: 1285583:CCASEI_RS07475
uniprot id: W5XT28
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1285583:CCASEI RS08080
gene id: 1285583:CCASEI_RS08080
uniprot id: W5XXF0
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1285583:CCASEI RS03745
gene id: 1285583:CCASEI_RS03745
uniprot id: W5XQX1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1285583:CCASEI RS01055
gene id: 1285583:CCASEI_RS01055
uniprot id: W5XPC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1285583:CCASEI RS05025
gene id: 1285583:CCASEI_RS05025
uniprot id: W5XZF4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1285583:CCASEI RS06760
gene id: 1285583:CCASEI_RS06760
uniprot id: W5XTC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1285583:CCASEI RS03125
gene id: 1285583:CCASEI_RS03125
uniprot id: W5XQG8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1285583:CCASEI RS07305
gene id: 1285583:CCASEI_RS07305
uniprot id: W5XSV3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1285583:CCASEI RS06745
gene id: 1285583:CCASEI_RS06745
uniprot id: W5XSQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1285583:CCASEI RS12705
gene id: 1285583:CCASEI_RS12705
uniprot id: W5XVQ2
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

1285583:CCASEI RS10200
gene id: 1285583:CCASEI_RS10200
uniprot id: W5XVB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1285583:CCASEI RS00185
gene id: 1285583:CCASEI_RS00185
uniprot id: W5XPN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1285583:CCASEI RS05505
gene id: 1285583:CCASEI_RS05505
uniprot id: W5XRW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

1285583:CCASEI RS00145
gene id: 1285583:CCASEI_RS00145
uniprot id: W5XWQ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1285583:CCASEI RS10340
gene id: 1285583:CCASEI_RS10340
uniprot id: W5XVA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1285583:CCASEI RS03020
gene id: 1285583:CCASEI_RS03020
uniprot id: W5XR54
names: Similarity
messages: Belongs to the WXG100 family.

1285583:CCASEI RS05500
gene id: 1285583:CCASEI_RS05500
uniprot id: W5XSK8
names: Similarity
messages: Belongs to the YggT family.

1285583:CCASEI RS11170
gene id: 1285583:CCASEI_RS11170
uniprot id: W5XVT2
names: Function
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

1285583:CCASEI RS10455
gene id: 1285583:CCASEI_RS10455
uniprot id: W5Y2E0
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1285583:CCASEI RS10035
gene id: 1285583:CCASEI_RS10035
uniprot id: W5Y270
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1285583:CCASEI RS12045
gene id: 1285583:CCASEI_RS12045
uniprot id: W5XVD6
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1285583:CCASEI RS09585
gene id: 1285583:CCASEI_RS09585
uniprot id: W5XV18
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1285583:CCASEI RS05595
gene id: 1285583:CCASEI_RS05595
uniprot id: W5XSR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1285583:CCASEI RS09505
gene id: 1285583:CCASEI_RS09505
uniprot id: W5XU65
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1285583:CCASEI RS03545
gene id: 1285583:CCASEI_RS03545
uniprot id: W5XRF9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1285583:CCASEI RS09685
gene id: 1285583:CCASEI_RS09685
uniprot id: W5XUA1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1285583:CCASEI RS11055
gene id: 1285583:CCASEI_RS11055
uniprot id: W5XUY8
names: Similarity
messages: Belongs to the peptidase M1 family.

1285583:CCASEI RS08030
gene id: 1285583:CCASEI_RS08030
uniprot id: W5Y106
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1285583:CCASEI RS06900
gene id: 1285583:CCASEI_RS06900
uniprot id: W5Y0F6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1285583:CCASEI RS10420
gene id: 1285583:CCASEI_RS10420
uniprot id: W5XUG4
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1285583:CCASEI RS05480
gene id: 1285583:CCASEI_RS05480
uniprot id: W5XRV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1285583:CCASEI RS10945
gene id: 1285583:CCASEI_RS10945
uniprot id: W5XUW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1285583:CCASEI RS00610
gene id: 1285583:CCASEI_RS00610
uniprot id: W5XP76
names: Function
names: Similarity
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.

1285583:CCASEI RS10665
gene id: 1285583:CCASEI_RS10665
uniprot id: W5XVH1
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1285583:CCASEI RS13970
gene id: 1285583:CCASEI_RS13970
uniprot id: W5XWK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1285583:CCASEI RS07820
gene id: 1285583:CCASEI_RS07820
uniprot id: W5XT82
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

1285583:CCASEI RS05840
gene id: 1285583:CCASEI_RS05840
uniprot id: W5XS33
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS05260
gene id: 1285583:CCASEI_RS05260
uniprot id: W5XZI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1285583:CCASEI RS11140
gene id: 1285583:CCASEI_RS11140
uniprot id: W5XVW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1285583:CCASEI RS04365
gene id: 1285583:CCASEI_RS04365
uniprot id: W5XS69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

1285583:CCASEI RS08875
gene id: 1285583:CCASEI_RS08875
uniprot id: W5XTT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

1285583:CCASEI RS11400
gene id: 1285583:CCASEI_RS11400
uniprot id: W5Y2W9
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS09125
gene id: 1285583:CCASEI_RS09125
uniprot id: W5XU04
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

1285583:CCASEI RS13665
gene id: 1285583:CCASEI_RS13665
uniprot id: W5XWE6
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS02960
gene id: 1285583:CCASEI_RS02960
uniprot id: W5XYC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1285583:CCASEI RS02070
gene id: 1285583:CCASEI_RS02070
uniprot id: W5XPX5
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1285583:CCASEI RS12135
gene id: 1285583:CCASEI_RS12135
uniprot id: W5XWF2
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1285583:CCASEI RS12945
gene id: 1285583:CCASEI_RS12945
uniprot id: W5XWS9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1285583:CCASEI RS13975
gene id: 1285583:CCASEI_RS13975
uniprot id: W5Y4C1
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS09935
gene id: 1285583:CCASEI_RS09935
uniprot id: W5Y257
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS12095
gene id: 1285583:CCASEI_RS12095
uniprot id: W5XVL0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1285583:CCASEI RS11070
gene id: 1285583:CCASEI_RS11070
uniprot id: W5XVR1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1285583:CCASEI RS07505
gene id: 1285583:CCASEI_RS07505
uniprot id: W5Y0S3
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1285583:CCASEI RS13480
gene id: 1285583:CCASEI_RS13480
uniprot id: W5XWA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1285583:CCASEI RS08620
gene id: 1285583:CCASEI_RS08620
uniprot id: W5XTJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1285583:CCASEI RS01625
gene id: 1285583:CCASEI_RS01625
uniprot id: W5XPV7
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS02770
gene id: 1285583:CCASEI_RS02770
uniprot id: W5XR11
names: Similarity
messages: Belongs to the asp23 family.

1285583:CCASEI RS09500
gene id: 1285583:CCASEI_RS09500
uniprot id: W5XU27
names: Similarity
messages: Belongs to the FBPase class 2 family.

1285583:CCASEI RS15350
gene id: 1285583:CCASEI_RS15350
uniprot id: W5XSY3
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1285583:CCASEI RS11280
gene id: 1285583:CCASEI_RS11280
uniprot id: W5XVV4
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1285583:CCASEI RS03985
gene id: 1285583:CCASEI_RS03985
uniprot id: W5XR77
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS07205
gene id: 1285583:CCASEI_RS07205
uniprot id: W5XSY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

1285583:CCASEI RS08745
gene id: 1285583:CCASEI_RS08745
uniprot id: W5XTR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1285583:CCASEI RS00320
gene id: 1285583:CCASEI_RS00320
uniprot id: W5XPQ5
names: Similarity
messages: Belongs to the AHA1 family.

1285583:CCASEI RS01715
gene id: 1285583:CCASEI_RS01715
uniprot id: W5XQI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

1285583:CCASEI RS07605
gene id: 1285583:CCASEI_RS07605
uniprot id: W5Y0U0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1285583:CCASEI RS13915
gene id: 1285583:CCASEI_RS13915
uniprot id: W5XWD0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.
messages: Decarboxylates branched-chain and aromatic alpha-keto acids to aldehydes.

1285583:CCASEI RS04655
gene id: 1285583:CCASEI_RS04655
uniprot id: W5XRI3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1285583:CCASEI RS02720
gene id: 1285583:CCASEI_RS02720
uniprot id: W5XR05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1285583:CCASEI RS04465
gene id: 1285583:CCASEI_RS04465
uniprot id: W5XRC9
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1285583:CCASEI RS02605
gene id: 1285583:CCASEI_RS02605
uniprot id: W5XQ76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1285583:CCASEI RS09320
gene id: 1285583:CCASEI_RS09320
uniprot id: W5XUX0
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1285583:CCASEI RS09750
gene id: 1285583:CCASEI_RS09750
uniprot id: W5XV02
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1285583:CCASEI RS03450
gene id: 1285583:CCASEI_RS03450
uniprot id: W5XQQ0
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1285583:CCASEI RS05340
gene id: 1285583:CCASEI_RS05340
uniprot id: W5XSM1
names: Similarity
messages: Belongs to the peptidase C40 family.

1285583:CCASEI RS12165
gene id: 1285583:CCASEI_RS12165
uniprot id: W5XWC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1285583:CCASEI RS05830
gene id: 1285583:CCASEI_RS05830
uniprot id: W5XST0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1285583:CCASEI RS08375
gene id: 1285583:CCASEI_RS08375
uniprot id: W5Y178
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1285583:CCASEI RS06085
gene id: 1285583:CCASEI_RS06085
uniprot id: W5XSY5
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1285583:CCASEI RS02585
gene id: 1285583:CCASEI_RS02585
uniprot id: W5XQY4
names: Subcellular Location Annotation
messages: Cytoplasm

1285583:CCASEI RS09630
gene id: 1285583:CCASEI_RS09630
uniprot id: W5XU89
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1285583:CCASEI RS11265
gene id: 1285583:CCASEI_RS11265
uniprot id: W5XV31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1285583:CCASEI RS11875
gene id: 1285583:CCASEI_RS11875
uniprot id: W5XW84
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1285583:CCASEI RS12105
gene id: 1285583:CCASEI_RS12105
uniprot id: W5XWE9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1285583:CCASEI RS12160
gene id: 1285583:CCASEI_RS12160
uniprot id: W5XWF7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1285583:CCASEI RS02575
gene id: 1285583:CCASEI_RS02575
uniprot id: W5XY53
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS05980
gene id: 1285583:CCASEI_RS05980
uniprot id: W5XSW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1285583:CCASEI RS10240
gene id: 1285583:CCASEI_RS10240
uniprot id: W5XUJ0
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

1285583:CCASEI RS08015
gene id: 1285583:CCASEI_RS08015
uniprot id: W5XTY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1285583:CCASEI RS06060
gene id: 1285583:CCASEI_RS06060
uniprot id: W5XSX9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1285583:CCASEI RS10275
gene id: 1285583:CCASEI_RS10275
uniprot id: W5XV93
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

1285583:CCASEI RS02390
gene id: 1285583:CCASEI_RS02390
uniprot id: W5XY25
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS09455
gene id: 1285583:CCASEI_RS09455
uniprot id: W5XU57
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1285583:CCASEI RS08310
gene id: 1285583:CCASEI_RS08310
uniprot id: W5XU39
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1285583:CCASEI RS10395
gene id: 1285583:CCASEI_RS10395
uniprot id: W5XUF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1285583:CCASEI RS13960
gene id: 1285583:CCASEI_RS13960
uniprot id: W5XXD7
names: Function
names: Similarity
messages: Belongs to the TrpF family.
messages: Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain.
messages: In the C-terminal section; belongs to the TrpF family.
messages: In the N-terminal section; belongs to the TrpC family.

1285583:CCASEI RS00160
gene id: 1285583:CCASEI_RS00160
uniprot id: W5XNX1
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

1285583:CCASEI RS02935
gene id: 1285583:CCASEI_RS02935
uniprot id: W5XYC4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1285583:CCASEI RS13720
gene id: 1285583:CCASEI_RS13720
uniprot id: W5Y462
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

1285583:CCASEI RS03070
gene id: 1285583:CCASEI_RS03070
uniprot id: W5XR61
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1285583:CCASEI RS03250
gene id: 1285583:CCASEI_RS03250
uniprot id: W5XQJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1285583:CCASEI RS02630
gene id: 1285583:CCASEI_RS02630
uniprot id: W5XQ81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1285583:CCASEI RS08035
gene id: 1285583:CCASEI_RS08035
uniprot id: W5XU42
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1285583:CCASEI RS05725
gene id: 1285583:CCASEI_RS05725
uniprot id: W5XSU2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1285583:CCASEI RS10215
gene id: 1285583:CCASEI_RS10215
uniprot id: W5XUI6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1285583:CCASEI RS10020
gene id: 1285583:CCASEI_RS10020
uniprot id: W5XV49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1285583:CCASEI RS05995
gene id: 1285583:CCASEI_RS05995
uniprot id: W5XS67
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1285583:CCASEI RS10780
gene id: 1285583:CCASEI_RS10780
uniprot id: W5Y2K4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1285583:CCASEI RS12720
gene id: 1285583:CCASEI_RS12720
uniprot id: W5XWN8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1285583:CCASEI RS12690
gene id: 1285583:CCASEI_RS12690
uniprot id: W5Y3J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1285583:CCASEI RS01025
gene id: 1285583:CCASEI_RS01025
uniprot id: W5XQ40
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1285583:CCASEI RS02865
gene id: 1285583:CCASEI_RS02865
uniprot id: W5XR67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1285583:CCASEI RS05955
gene id: 1285583:CCASEI_RS05955
uniprot id: W5XSV4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1285583:CCASEI RS12950
gene id: 1285583:CCASEI_RS12950
uniprot id: W5XWS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1285583:CCASEI RS07810
gene id: 1285583:CCASEI_RS07810
uniprot id: W5XTU6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1285583:CCASEI RS05185
gene id: 1285583:CCASEI_RS05185
uniprot id: W5XSJ2
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1285583:CCASEI RS04955
gene id: 1285583:CCASEI_RS04955
uniprot id: W5XSB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1285583:CCASEI RS10610
gene id: 1285583:CCASEI_RS10610
uniprot id: W5Y2G9
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1285583:CCASEI RS13890
gene id: 1285583:CCASEI_RS13890
uniprot id: W5XWC5
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS01600
gene id: 1285583:CCASEI_RS01600
uniprot id: W5XXN6
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1285583:CCASEI RS05760
gene id: 1285583:CCASEI_RS05760
uniprot id: W5XS19
names: Similarity
messages: Belongs to the PrpF family.

1285583:CCASEI RS00615
gene id: 1285583:CCASEI_RS00615
uniprot id: W5XX10
names: Function
names: Similarity
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2-methylpyrimidine (HMP).

1285583:CCASEI RS02800
gene id: 1285583:CCASEI_RS02800
uniprot id: W5XQB2
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1285583:CCASEI RS07565
gene id: 1285583:CCASEI_RS07565
uniprot id: W5XTR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1285583:CCASEI RS05975
gene id: 1285583:CCASEI_RS05975
uniprot id: W5XSZ4
names: Similarity
messages: Belongs to the DprA/Smf family.

1285583:CCASEI RS13425
gene id: 1285583:CCASEI_RS13425
uniprot id: W5XW28
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1285583:CCASEI RS05090
gene id: 1285583:CCASEI_RS05090
uniprot id: W5XSE0
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS11105
gene id: 1285583:CCASEI_RS11105
uniprot id: W5Y2R4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1285583:CCASEI RS13640
gene id: 1285583:CCASEI_RS13640
uniprot id: W5XWE1
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS10335
gene id: 1285583:CCASEI_RS10335
uniprot id: W5XVE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1285583:CCASEI RS12740
gene id: 1285583:CCASEI_RS12740
uniprot id: W5Y3K8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1285583:CCASEI RS06940
gene id: 1285583:CCASEI_RS06940
uniprot id: W5XSQ1
names: Subcellular Location Annotation
messages: Secreted

1285583:CCASEI RS10970
gene id: 1285583:CCASEI_RS10970
uniprot id: W5XUX1
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1285583:CCASEI RS01095
gene id: 1285583:CCASEI_RS01095
uniprot id: W5XQ59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1285583:CCASEI RS09485
gene id: 1285583:CCASEI_RS09485
uniprot id: W5Y1X5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1285583:CCASEI RS07580
gene id: 1285583:CCASEI_RS07580
uniprot id: W5Y0T6
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1285583:CCASEI RS07200
gene id: 1285583:CCASEI_RS07200
uniprot id: W5XST8
names: Similarity
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Homohexamer. Assembles into a hexameric ring structure.

1285583:CCASEI RS04410
gene id: 1285583:CCASEI_RS04410
uniprot id: W5XZ50
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1285583:CCASEI RS05935
gene id: 1285583:CCASEI_RS05935
uniprot id: W5XS59
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1285583:CCASEI RS13895
gene id: 1285583:CCASEI_RS13895
uniprot id: W5XWI6
names: Similarity
messages: Belongs to the peptidase C56 family.

1285583:CCASEI RS05705
gene id: 1285583:CCASEI_RS05705
uniprot id: W5XSQ4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1285583:CCASEI RS03385
gene id: 1285583:CCASEI_RS03385
uniprot id: W5XYK0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1285583:CCASEI RS05245
gene id: 1285583:CCASEI_RS05245
uniprot id: W5XSG4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1285583:CCASEI RS06850
gene id: 1285583:CCASEI_RS06850
uniprot id: W5Y0F0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1285583:CCASEI RS00625
gene id: 1285583:CCASEI_RS00625
uniprot id: W5XPV0
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS12225
gene id: 1285583:CCASEI_RS12225
uniprot id: W5XVN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1285583:CCASEI RS04475
gene id: 1285583:CCASEI_RS04475
uniprot id: W5XZ63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1285583:CCASEI RS13470
gene id: 1285583:CCASEI_RS13470
uniprot id: W5XX33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1285583:CCASEI RS12260
gene id: 1285583:CCASEI_RS12260
uniprot id: W5XWE7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1285583:CCASEI RS09860
gene id: 1285583:CCASEI_RS09860
uniprot id: W5Y241
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1285583:CCASEI RS08625
gene id: 1285583:CCASEI_RS08625
uniprot id: W5XTN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1285583:CCASEI RS02540
gene id: 1285583:CCASEI_RS02540
uniprot id: W5XQC0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

1285583:CCASEI RS12040
gene id: 1285583:CCASEI_RS12040
uniprot id: W5XWB2
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1285583:CCASEI RS13565
gene id: 1285583:CCASEI_RS13565
uniprot id: W5XWC6
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1285583:CCASEI RS02970
gene id: 1285583:CCASEI_RS02970
uniprot id: W5XR46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1285583:CCASEI RS09955
gene id: 1285583:CCASEI_RS09955
uniprot id: W5XUF2
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1285583:CCASEI RS00490
gene id: 1285583:CCASEI_RS00490
uniprot id: W5XWY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1285583:CCASEI RS13385
gene id: 1285583:CCASEI_RS13385
uniprot id: W5Y3Z2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.

1285583:CCASEI RS04275
gene id: 1285583:CCASEI_RS04275
uniprot id: W5XR97
names: Similarity
messages: Belongs to the AHA1 family.

1285583:CCASEI RS08650
gene id: 1285583:CCASEI_RS08650
uniprot id: W5XTP5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1285583:CCASEI RS05930
gene id: 1285583:CCASEI_RS05930
uniprot id: W5XSU9
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS07130
gene id: 1285583:CCASEI_RS07130
uniprot id: W5Y0J8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1285583:CCASEI RS06810
gene id: 1285583:CCASEI_RS06810
uniprot id: W5XTD2
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1285583:CCASEI RS08830
gene id: 1285583:CCASEI_RS08830
uniprot id: W5Y1I3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

1285583:CCASEI RS07880
gene id: 1285583:CCASEI_RS07880
uniprot id: W5XTV8
names: Similarity
messages: Belongs to the universal stress protein A family.

1285583:CCASEI RS09865
gene id: 1285583:CCASEI_RS09865
uniprot id: W5XV60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1285583:CCASEI RS02715
gene id: 1285583:CCASEI_RS02715
uniprot id: W5XR39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1285583:CCASEI RS04810
gene id: 1285583:CCASEI_RS04810
uniprot id: W5XZC3
names: Similarity
messages: Belongs to the glutamate synthase family.

1285583:CCASEI RS01725
gene id: 1285583:CCASEI_RS01725
uniprot id: W5XPX2
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1285583:CCASEI RS11000
gene id: 1285583:CCASEI_RS11000
uniprot id: W5Y2P6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1285583:CCASEI RS03145
gene id: 1285583:CCASEI_RS03145
uniprot id: W5XR76
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1285583:CCASEI RS02370
gene id: 1285583:CCASEI_RS02370
uniprot id: W5XQZ0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1285583:CCASEI RS06715
gene id: 1285583:CCASEI_RS06715
uniprot id: W5XSL2
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1285583:CCASEI RS07250
gene id: 1285583:CCASEI_RS07250
uniprot id: W5XSU6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

1285583:CCASEI RS13530
gene id: 1285583:CCASEI_RS13530
uniprot id: W5XX45
names: Similarity
messages: Belongs to the PspA/IM30 family.

1285583:CCASEI RS07575
gene id: 1285583:CCASEI_RS07575
uniprot id: W5XT43
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1285583:CCASEI RS13815
gene id: 1285583:CCASEI_RS13815
uniprot id: W5XWA8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1285583:CCASEI RS08335
gene id: 1285583:CCASEI_RS08335
uniprot id: W5XU45
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1285583:CCASEI RS05855
gene id: 1285583:CCASEI_RS05855
uniprot id: W5XST4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1285583:CCASEI RS12800
gene id: 1285583:CCASEI_RS12800
uniprot id: W5XWP5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1285583:CCASEI RS13080
gene id: 1285583:CCASEI_RS13080
uniprot id: W5XVX0
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

1285583:CCASEI RS10870
gene id: 1285583:CCASEI_RS10870
uniprot id: W5XUN8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1285583:CCASEI RS09620
gene id: 1285583:CCASEI_RS09620
uniprot id: W5XUX7
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

1285583:CCASEI RS06055
gene id: 1285583:CCASEI_RS06055
uniprot id: W5XT10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1285583:CCASEI RS07625
gene id: 1285583:CCASEI_RS07625
uniprot id: W5XT53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1285583:CCASEI RS01730
gene id: 1285583:CCASEI_RS01730
uniprot id: W5XXQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1285583:CCASEI RS09520
gene id: 1285583:CCASEI_RS09520
uniprot id: W5XUV9
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS08755
gene id: 1285583:CCASEI_RS08755
uniprot id: W5XUI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1285583:CCASEI RS00140
gene id: 1285583:CCASEI_RS00140
uniprot id: W5XNX0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1285583:CCASEI RS05210
gene id: 1285583:CCASEI_RS05210
uniprot id: W5XZH6
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS07535
gene id: 1285583:CCASEI_RS07535
uniprot id: W5XTU5
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1285583:CCASEI RS00705
gene id: 1285583:CCASEI_RS00705
uniprot id: W5XP61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1285583:CCASEI RS08960
gene id: 1285583:CCASEI_RS08960
uniprot id: W5XUQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1285583:CCASEI RS01030
gene id: 1285583:CCASEI_RS01030
uniprot id: W5XPC4
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-67 and Arg-70) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

1285583:CCASEI RS04020
gene id: 1285583:CCASEI_RS04020
uniprot id: W5XS09
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1285583:CCASEI RS04395
gene id: 1285583:CCASEI_RS04395
uniprot id: W5XS05
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1285583:CCASEI RS14060
gene id: 1285583:CCASEI_RS14060
uniprot id: W5XXG5
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS12815
gene id: 1285583:CCASEI_RS12815
uniprot id: W5Y3M2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1285583:CCASEI RS10775
gene id: 1285583:CCASEI_RS10775
uniprot id: W5XUT0
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

1285583:CCASEI RS04300
gene id: 1285583:CCASEI_RS04300
uniprot id: W5XRA1
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1285583:CCASEI RS13955
gene id: 1285583:CCASEI_RS13955
uniprot id: W5XXD5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1285583:CCASEI RS06580
gene id: 1285583:CCASEI_RS06580
uniprot id: W5XTA1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1285583:CCASEI RS10005
gene id: 1285583:CCASEI_RS10005
uniprot id: W5XUG0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1285583:CCASEI RS13330
gene id: 1285583:CCASEI_RS13330
uniprot id: W5XW14
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1285583:CCASEI RS04590
gene id: 1285583:CCASEI_RS04590
uniprot id: W5XZ84
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS05270
gene id: 1285583:CCASEI_RS05270
uniprot id: W5XSG7
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1285583:CCASEI RS09475
gene id: 1285583:CCASEI_RS09475
uniprot id: W5XU22
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1285583:CCASEI RS12140
gene id: 1285583:CCASEI_RS12140
uniprot id: W5XWC4
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1285583:CCASEI RS03955
gene id: 1285583:CCASEI_RS03955
uniprot id: W5XR41
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1285583:CCASEI RS05950
gene id: 1285583:CCASEI_RS05950
uniprot id: W5XSY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1285583:CCASEI RS11870
gene id: 1285583:CCASEI_RS11870
uniprot id: W5XWB5
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

1285583:CCASEI RS12575
gene id: 1285583:CCASEI_RS12575
uniprot id: W5XWK3
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1285583:CCASEI RS09545
gene id: 1285583:CCASEI_RS09545
uniprot id: W5XUW4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1285583:CCASEI RS04345
gene id: 1285583:CCASEI_RS04345
uniprot id: W5XRZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1285583:CCASEI RS00590
gene id: 1285583:CCASEI_RS00590
uniprot id: W5XX05
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1285583:CCASEI RS13910
gene id: 1285583:CCASEI_RS13910
uniprot id: W5XXC7
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1285583:CCASEI RS08645
gene id: 1285583:CCASEI_RS08645
uniprot id: W5XTK5
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1285583:CCASEI RS03035
gene id: 1285583:CCASEI_RS03035
uniprot id: W5XYE1
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1285583:CCASEI RS08525
gene id: 1285583:CCASEI_RS08525
uniprot id: W5XTM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1285583:CCASEI RS08205
gene id: 1285583:CCASEI_RS08205
uniprot id: W5XTA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1285583:CCASEI RS10650
gene id: 1285583:CCASEI_RS10650
uniprot id: W5XUJ6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1285583:CCASEI RS06095
gene id: 1285583:CCASEI_RS06095
uniprot id: W5XS92
names: Similarity
messages: Belongs to the MQO family.

1285583:CCASEI RS05635
gene id: 1285583:CCASEI_RS05635
uniprot id: W5XRY7
names: Similarity
messages: Belongs to the HSP15 family.

1285583:CCASEI RS07235
gene id: 1285583:CCASEI_RS07235
uniprot id: W5Y0L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1285583:CCASEI RS07890
gene id: 1285583:CCASEI_RS07890
uniprot id: W5XT94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1285583:CCASEI RS06135
gene id: 1285583:CCASEI_RS06135
uniprot id: W5XSZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1285583:CCASEI RS13145
gene id: 1285583:CCASEI_RS13145
uniprot id: W5XWX2
names: Similarity
messages: In the C-terminal section; belongs to the anthranilate synthase component I family.

1285583:CCASEI RS06365
gene id: 1285583:CCASEI_RS06365
uniprot id: W5XSH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1285583:CCASEI RS09650
gene id: 1285583:CCASEI_RS09650
uniprot id: W5XU50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1285583:CCASEI RS03375
gene id: 1285583:CCASEI_RS03375
uniprot id: W5XQN3
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1285583:CCASEI RS08870
gene id: 1285583:CCASEI_RS08870
uniprot id: W5XTQ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

1285583:CCASEI RS12425
gene id: 1285583:CCASEI_RS12425
uniprot id: W5Y3E4
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

1285583:CCASEI RS02735
gene id: 1285583:CCASEI_RS02735
uniprot id: W5XY82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

1285583:CCASEI RS03400
gene id: 1285583:CCASEI_RS03400
uniprot id: W5XQN8
names: Similarity
messages: Belongs to the peptidase S11 family.

1285583:CCASEI RS07190
gene id: 1285583:CCASEI_RS07190
uniprot id: W5XTP0
names: Caution
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

1285583:CCASEI RS07785
gene id: 1285583:CCASEI_RS07785
uniprot id: W5XTU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1285583:CCASEI RS09155
gene id: 1285583:CCASEI_RS09155
uniprot id: W5Y1S7
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS05515
gene id: 1285583:CCASEI_RS05515
uniprot id: W5XZM5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1285583:CCASEI RS07730
gene id: 1285583:CCASEI_RS07730
uniprot id: W5XTX8
names: Similarity
messages: Belongs to the UPF0434 family.

1285583:CCASEI RS06890
gene id: 1285583:CCASEI_RS06890
uniprot id: W5XSP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1285583:CCASEI RS11635
gene id: 1285583:CCASEI_RS11635
uniprot id: W5Y338
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS02775
gene id: 1285583:CCASEI_RS02775
uniprot id: W5XQA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1285583:CCASEI RS02795
gene id: 1285583:CCASEI_RS02795
uniprot id: W5XR15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1285583:CCASEI RS10860
gene id: 1285583:CCASEI_RS10860
uniprot id: W5XVQ6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1285583:CCASEI RS07540
gene id: 1285583:CCASEI_RS07540
uniprot id: W5XTQ7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1285583:CCASEI RS09600
gene id: 1285583:CCASEI_RS09600
uniprot id: W5XU85
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1285583:CCASEI RS03595
gene id: 1285583:CCASEI_RS03595
uniprot id: W5XRH0
names: Similarity
messages: Belongs to the AccD/PCCB family.

1285583:CCASEI RS01680
gene id: 1285583:CCASEI_RS01680
uniprot id: W5XXP7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1285583:CCASEI RS02805
gene id: 1285583:CCASEI_RS02805
uniprot id: W5XQF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1285583:CCASEI RS07825
gene id: 1285583:CCASEI_RS07825
uniprot id: W5Y0X2
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS02420
gene id: 1285583:CCASEI_RS02420
uniprot id: W5XQZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1285583:CCASEI RS08955
gene id: 1285583:CCASEI_RS08955
uniprot id: W5Y1N8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1285583:CCASEI RS05455
gene id: 1285583:CCASEI_RS05455
uniprot id: W5XRV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1285583:CCASEI RS05445
gene id: 1285583:CCASEI_RS05445
uniprot id: W5XSN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1285583:CCASEI RS05450
gene id: 1285583:CCASEI_RS05450
uniprot id: W5XSJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1285583:CCASEI RS05370
gene id: 1285583:CCASEI_RS05370
uniprot id: W5XSI5
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.
messages: Homodimer.

1285583:CCASEI RS12325
gene id: 1285583:CCASEI_RS12325
uniprot id: W5Y3C9
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS10930
gene id: 1285583:CCASEI_RS10930
uniprot id: W5XVS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1285583:CCASEI RS07555
gene id: 1285583:CCASEI_RS07555
uniprot id: W5Y0T1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1285583:CCASEI RS10520
gene id: 1285583:CCASEI_RS10520
uniprot id: W5XUH8
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1285583:CCASEI RS06460
gene id: 1285583:CCASEI_RS06460
uniprot id: W5XSL4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1285583:CCASEI RS00890
gene id: 1285583:CCASEI_RS00890
uniprot id: W5XP94
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1285583:CCASEI RS10015
gene id: 1285583:CCASEI_RS10015
uniprot id: W5XV87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1285583:CCASEI RS14145
gene id: 1285583:CCASEI_RS14145
uniprot id: W5XWK9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1285583:CCASEI RS14535
gene id: 1285583:CCASEI_RS14535
uniprot id: W5Y3B5
names: Similarity
messages: Belongs to the mycobacterial A85 antigen family.

1285583:CCASEI RS09870
gene id: 1285583:CCASEI_RS09870
uniprot id: W5XV25
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

1285583:CCASEI RS05285
gene id: 1285583:CCASEI_RS05285
uniprot id: W5XZI7
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1285583:CCASEI RS06730
gene id: 1285583:CCASEI_RS06730
uniprot id: W5XTG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1285583:CCASEI RS11275
gene id: 1285583:CCASEI_RS11275
uniprot id: W5XVY6
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1285583:CCASEI RS12730
gene id: 1285583:CCASEI_RS12730
uniprot id: W5XVQ7
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1285583:CCASEI RS07440
gene id: 1285583:CCASEI_RS07440
uniprot id: W5XTN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1285583:CCASEI RS04450
gene id: 1285583:CCASEI_RS04450
uniprot id: W5XZ59
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS05765
gene id: 1285583:CCASEI_RS05765
uniprot id: W5XS15
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1285583:CCASEI RS03435
gene id: 1285583:CCASEI_RS03435
uniprot id: W5XYL1
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1285583:CCASEI RS13150
gene id: 1285583:CCASEI_RS13150
uniprot id: W5XWW4
names: Similarity
messages: Belongs to the AccD/PCCB family.

1285583:CCASEI RS02785
gene id: 1285583:CCASEI_RS02785
uniprot id: W5XY92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1285583:CCASEI RS11345
gene id: 1285583:CCASEI_RS11345
uniprot id: W5Y2V8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1285583:CCASEI RS07910
gene id: 1285583:CCASEI_RS07910
uniprot id: W5XT60
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS04650
gene id: 1285583:CCASEI_RS04650
uniprot id: W5XRG1
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

1285583:CCASEI RS06770
gene id: 1285583:CCASEI_RS06770
uniprot id: W5XSR3
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1285583:CCASEI RS01325
gene id: 1285583:CCASEI_RS01325
uniprot id: W5XPH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1285583:CCASEI RS01490
gene id: 1285583:CCASEI_RS01490
uniprot id: W5XQI9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1285583:CCASEI RS03340
gene id: 1285583:CCASEI_RS03340
uniprot id: W5XRH3
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1285583:CCASEI RS12030
gene id: 1285583:CCASEI_RS12030
uniprot id: W5Y391
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1285583:CCASEI RS10995
gene id: 1285583:CCASEI_RS10995
uniprot id: W5XUX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1285583:CCASEI RS10980
gene id: 1285583:CCASEI_RS10980
uniprot id: W5XVT1
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1285583:CCASEI RS01530
gene id: 1285583:CCASEI_RS01530
uniprot id: W5XPP3
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1285583:CCASEI RS05490
gene id: 1285583:CCASEI_RS05490
uniprot id: W5XZM1
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1285583:CCASEI RS04580
gene id: 1285583:CCASEI_RS04580
uniprot id: W5XRE9
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1285583:CCASEI RS08365
gene id: 1285583:CCASEI_RS08365
uniprot id: W5XTD9
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS06685
gene id: 1285583:CCASEI_RS06685
uniprot id: W5XTB2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1285583:CCASEI RS00700
gene id: 1285583:CCASEI_RS00700
uniprot id: W5XPW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1285583:CCASEI RS11905
gene id: 1285583:CCASEI_RS11905
uniprot id: W5XVB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1285583:CCASEI RS11325
gene id: 1285583:CCASEI_RS11325
uniprot id: W5XVZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1285583:CCASEI RS10160
gene id: 1285583:CCASEI_RS10160
uniprot id: W5XUI2
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

1285583:CCASEI RS14040
gene id: 1285583:CCASEI_RS14040
uniprot id: W5XXG8
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1285583:CCASEI RS07340
gene id: 1285583:CCASEI_RS07340
uniprot id: W5Y0N8
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

1285583:CCASEI RS12680
gene id: 1285583:CCASEI_RS12680
uniprot id: W5XVP7
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS03485
gene id: 1285583:CCASEI_RS03485
uniprot id: W5XYM3
names: Similarity
messages: Belongs to the citrate synthase family.

1285583:CCASEI RS06405
gene id: 1285583:CCASEI_RS06405
uniprot id: W5XT78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1285583:CCASEI RS11185
gene id: 1285583:CCASEI_RS11185
uniprot id: W5Y2T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1285583:CCASEI RS12430
gene id: 1285583:CCASEI_RS12430
uniprot id: W5XWJ4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1285583:CCASEI RS13020
gene id: 1285583:CCASEI_RS13020
uniprot id: W5XWU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.

1285583:CCASEI RS04100
gene id: 1285583:CCASEI_RS04100
uniprot id: W5XRV7
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS06390
gene id: 1285583:CCASEI_RS06390
uniprot id: W5XSJ5
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1285583:CCASEI RS04725
gene id: 1285583:CCASEI_RS04725
uniprot id: W5XS66
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1285583:CCASEI RS10410
gene id: 1285583:CCASEI_RS10410
uniprot id: W5XVF9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

1285583:CCASEI RS03025
gene id: 1285583:CCASEI_RS03025
uniprot id: W5XQE9
names: Similarity
messages: Belongs to the WXG100 family.

1285583:CCASEI RS07170
gene id: 1285583:CCASEI_RS07170
uniprot id: W5XST5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1285583:CCASEI RS09195
gene id: 1285583:CCASEI_RS09195
uniprot id: W5XUQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

1285583:CCASEI RS07685
gene id: 1285583:CCASEI_RS07685
uniprot id: W5XTX2
names: Similarity
messages: Belongs to the TlyA family.

1285583:CCASEI RS13240
gene id: 1285583:CCASEI_RS13240
uniprot id: W5Y3V6
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

1285583:CCASEI RS01770
gene id: 1285583:CCASEI_RS01770
uniprot id: W5XQI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1285583:CCASEI RS06860
gene id: 1285583:CCASEI_RS06860
uniprot id: W5XTE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1285583:CCASEI RS07775
gene id: 1285583:CCASEI_RS07775
uniprot id: W5Y0W3
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1285583:CCASEI RS00975
gene id: 1285583:CCASEI_RS00975
uniprot id: W5XQ27
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

1285583:CCASEI RS13550
gene id: 1285583:CCASEI_RS13550
uniprot id: W5XX53
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS06240
gene id: 1285583:CCASEI_RS06240
uniprot id: W5XSC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1285583:CCASEI RS13255
gene id: 1285583:CCASEI_RS13255
uniprot id: W5XVZ9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

1285583:CCASEI RS06885
gene id: 1285583:CCASEI_RS06885
uniprot id: W5XTE6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1285583:CCASEI RS03095
gene id: 1285583:CCASEI_RS03095
uniprot id: W5XR66
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1285583:CCASEI RS01550
gene id: 1285583:CCASEI_RS01550
uniprot id: W5XQJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1285583:CCASEI RS07560
gene id: 1285583:CCASEI_RS07560
uniprot id: W5XTU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1285583:CCASEI RS09205
gene id: 1285583:CCASEI_RS09205
uniprot id: W5XTX9
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS07455
gene id: 1285583:CCASEI_RS07455
uniprot id: W5Y0R3
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1285583:CCASEI RS04045
gene id: 1285583:CCASEI_RS04045
uniprot id: W5XS14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1285583:CCASEI RS04070
gene id: 1285583:CCASEI_RS04070
uniprot id: W5XS18
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1285583:CCASEI RS13375
gene id: 1285583:CCASEI_RS13375
uniprot id: W5XW20
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1285583:CCASEI RS07835
gene id: 1285583:CCASEI_RS07835
uniprot id: W5XTU9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1285583:CCASEI RS06740
gene id: 1285583:CCASEI_RS06740
uniprot id: W5XSL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1285583:CCASEI RS00560
gene id: 1285583:CCASEI_RS00560
uniprot id: W5XP62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1285583:CCASEI RS12440
gene id: 1285583:CCASEI_RS12440
uniprot id: W5XVK3
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS04340
gene id: 1285583:CCASEI_RS04340
uniprot id: W5XS65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1285583:CCASEI RS07445
gene id: 1285583:CCASEI_RS07445
uniprot id: W5XSX8
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1285583:CCASEI RS05415
gene id: 1285583:CCASEI_RS05415
uniprot id: W5XSN4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1285583:CCASEI RS07030
gene id: 1285583:CCASEI_RS07030
uniprot id: W5Y0H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1285583:CCASEI RS10825
gene id: 1285583:CCASEI_RS10825
uniprot id: W5XUU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1285583:CCASEI RS06385
gene id: 1285583:CCASEI_RS06385
uniprot id: W5XSG9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1285583:CCASEI RS03030
gene id: 1285583:CCASEI_RS03030
uniprot id: W5XQK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1285583:CCASEI RS08265
gene id: 1285583:CCASEI_RS08265
uniprot id: W5XTB7
names: Similarity
messages: Belongs to the isochorismate synthase family.

1285583:CCASEI RS06310
gene id: 1285583:CCASEI_RS06310
uniprot id: W5XSE1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1285583:CCASEI RS02115
gene id: 1285583:CCASEI_RS02115
uniprot id: W5XQP8
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1285583:CCASEI RS09895
gene id: 1285583:CCASEI_RS09895
uniprot id: W5XV29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1285583:CCASEI RS05235
gene id: 1285583:CCASEI_RS05235
uniprot id: W5XZH8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1285583:CCASEI RS04455
gene id: 1285583:CCASEI_RS04455
uniprot id: W5XS83
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS10155
gene id: 1285583:CCASEI_RS10155
uniprot id: W5XUC4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1285583:CCASEI RS13965
gene id: 1285583:CCASEI_RS13965
uniprot id: W5XWE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1285583:CCASEI RS03680
gene id: 1285583:CCASEI_RS03680
uniprot id: W5XYR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1285583:CCASEI RS05690
gene id: 1285583:CCASEI_RS05690
uniprot id: W5XZQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1285583:CCASEI RS10505
gene id: 1285583:CCASEI_RS10505
uniprot id: W5Y2E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1285583:CCASEI RS00765
gene id: 1285583:CCASEI_RS00765
uniprot id: W5XX47
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS13830
gene id: 1285583:CCASEI_RS13830
uniprot id: W5XXA8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1285583:CCASEI RS03105
gene id: 1285583:CCASEI_RS03105
uniprot id: W5XQM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1285583:CCASEI RS07900
gene id: 1285583:CCASEI_RS07900
uniprot id: W5XU12
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS03475
gene id: 1285583:CCASEI_RS03475
uniprot id: W5XQQ5
names: Similarity
messages: Belongs to the PrpD family.

1285583:CCASEI RS12960
gene id: 1285583:CCASEI_RS12960
uniprot id: W5XW07
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1285583:CCASEI RS00390
gene id: 1285583:CCASEI_RS00390
uniprot id: W5XWW0
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1285583:CCASEI RS07675
gene id: 1285583:CCASEI_RS07675
uniprot id: W5XT62
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1285583:CCASEI RS05680
gene id: 1285583:CCASEI_RS05680
uniprot id: W5XS02
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1285583:CCASEI RS09550
gene id: 1285583:CCASEI_RS09550
uniprot id: W5XU36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

1285583:CCASEI RS02525
gene id: 1285583:CCASEI_RS02525
uniprot id: W5XR13
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS12930
gene id: 1285583:CCASEI_RS12930
uniprot id: W5XVU4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1285583:CCASEI RS03225
gene id: 1285583:CCASEI_RS03225
uniprot id: W5XQJ1
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1285583:CCASEI RS02880
gene id: 1285583:CCASEI_RS02880
uniprot id: W5XQH6
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS07380
gene id: 1285583:CCASEI_RS07380
uniprot id: W5XT11
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1285583:CCASEI RS10715
gene id: 1285583:CCASEI_RS10715
uniprot id: W5XVI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpqB lipoprotein family.
messages: Cell membrane

1285583:CCASEI RS07595
gene id: 1285583:CCASEI_RS07595
uniprot id: W5XT07
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1285583:CCASEI RS12290
gene id: 1285583:CCASEI_RS12290
uniprot id: W5XVH7
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1285583:CCASEI RS06870
gene id: 1285583:CCASEI_RS06870
uniprot id: W5XSS8
names: Similarity
messages: Belongs to the peptidase A24 family.

1285583:CCASEI RS00045
gene id: 1285583:CCASEI_RS00045
uniprot id: W5XNV6
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1285583:CCASEI RS05780
gene id: 1285583:CCASEI_RS05780
uniprot id: W5XSS0
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1285583:CCASEI RS06430
gene id: 1285583:CCASEI_RS06430
uniprot id: W5XT80
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1285583:CCASEI RS05095
gene id: 1285583:CCASEI_RS05095
uniprot id: W5XRP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

1285583:CCASEI RS01785
gene id: 1285583:CCASEI_RS01785
uniprot id: W5XXR7
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1285583:CCASEI RS12580
gene id: 1285583:CCASEI_RS12580
uniprot id: W5XVN0
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1285583:CCASEI RS06370
gene id: 1285583:CCASEI_RS06370
uniprot id: W5Y085
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1285583:CCASEI RS05815
gene id: 1285583:CCASEI_RS05815
uniprot id: W5XS27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1285583:CCASEI RS02440
gene id: 1285583:CCASEI_RS02440
uniprot id: W5XQA1
names: Similarity
messages: Belongs to the peptidase S33 family.

1285583:CCASEI RS12585
gene id: 1285583:CCASEI_RS12585
uniprot id: W5XVU7
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1285583:CCASEI RS04015
gene id: 1285583:CCASEI_RS04015
uniprot id: W5XYZ0
names: Similarity
messages: Belongs to the TPP enzyme family.

1285583:CCASEI RS02820
gene id: 1285583:CCASEI_RS02820
uniprot id: W5XR19
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1285583:CCASEI RS08565
gene id: 1285583:CCASEI_RS08565
uniprot id: W5XU94
names: Similarity
messages: Belongs to the UPF0045 family.

1285583:CCASEI RS05850
gene id: 1285583:CCASEI_RS05850
uniprot id: W5XSW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1285583:CCASEI RS12475
gene id: 1285583:CCASEI_RS12475
uniprot id: W5Y3F2
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

1285583:CCASEI RS12600
gene id: 1285583:CCASEI_RS12600
uniprot id: W5XWK8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1285583:CCASEI RS11865
gene id: 1285583:CCASEI_RS11865
uniprot id: W5Y372
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

1285583:CCASEI RS12675
gene id: 1285583:CCASEI_RS12675
uniprot id: W5XWM2
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS08970
gene id: 1285583:CCASEI_RS08970
uniprot id: W5XTV1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1285583:CCASEI RS12595
gene id: 1285583:CCASEI_RS12595
uniprot id: W5XWM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1285583:CCASEI RS04125
gene id: 1285583:CCASEI_RS04125
uniprot id: W5XR69
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

1285583:CCASEI RS13485
gene id: 1285583:CCASEI_RS13485
uniprot id: W5Y414
names: Similarity
messages: Belongs to the universal stress protein A family.

1285583:CCASEI RS01440
gene id: 1285583:CCASEI_RS01440
uniprot id: W5XQI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1285583:CCASEI RS05965
gene id: 1285583:CCASEI_RS05965
uniprot id: W5XS62
names: Similarity
messages: Belongs to the UPF0102 family.

1285583:CCASEI RS02910
gene id: 1285583:CCASEI_RS02910
uniprot id: W5XYB9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1285583:CCASEI RS10225
gene id: 1285583:CCASEI_RS10225
uniprot id: W5XVB9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1285583:CCASEI RS13560
gene id: 1285583:CCASEI_RS13560
uniprot id: W5XW52
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1285583:CCASEI RS03925
gene id: 1285583:CCASEI_RS03925
uniprot id: W5XRT0
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1285583:CCASEI RS09225
gene id: 1285583:CCASEI_RS09225
uniprot id: W5XUQ3
names: Function
names: Similarity
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).

1285583:CCASEI RS13945
gene id: 1285583:CCASEI_RS13945
uniprot id: W5XWJ6
names: Cofactor
names: Similarity
messages: Belongs to the anthranilate synthase component I family.
messages: Binds 1 Mg(2+) ion per subunit.

1285583:CCASEI RS06120
gene id: 1285583:CCASEI_RS06120
uniprot id: W5XS98
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1285583:CCASEI RS08750
gene id: 1285583:CCASEI_RS08750
uniprot id: W5Y1G6
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1285583:CCASEI RS11075
gene id: 1285583:CCASEI_RS11075
uniprot id: W5XUT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1285583:CCASEI RS02615
gene id: 1285583:CCASEI_RS02615
uniprot id: W5XY57
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1285583:CCASEI RS00205
gene id: 1285583:CCASEI_RS00205
uniprot id: W5XPL9
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS05835
gene id: 1285583:CCASEI_RS05835
uniprot id: W5XS37
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1285583:CCASEI RS14090
gene id: 1285583:CCASEI_RS14090
uniprot id: W5XXH4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1285583:CCASEI RS06320
gene id: 1285583:CCASEI_RS06320
uniprot id: W5Y037
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1285583:CCASEI RS01915
gene id: 1285583:CCASEI_RS01915
uniprot id: W5XQL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1285583:CCASEI RS03610
gene id: 1285583:CCASEI_RS03610
uniprot id: W5XYQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1285583:CCASEI RS00645
gene id: 1285583:CCASEI_RS00645
uniprot id: W5XPW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1285583:CCASEI RS12445
gene id: 1285583:CCASEI_RS12445
uniprot id: W5XVS0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1285583:CCASEI RS11600
gene id: 1285583:CCASEI_RS11600
uniprot id: W5XVD0
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1285583:CCASEI RS04030
gene id: 1285583:CCASEI_RS04030
uniprot id: W5XR51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1285583:CCASEI RS07220
gene id: 1285583:CCASEI_RS07220
uniprot id: W5XTK1
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1285583:CCASEI RS01950
gene id: 1285583:CCASEI_RS01950
uniprot id: W5XXU7
names: Similarity
messages: Belongs to the GSP E family.

1285583:CCASEI RS02325
gene id: 1285583:CCASEI_RS02325
uniprot id: W5XQT7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1285583:CCASEI RS07655
gene id: 1285583:CCASEI_RS07655
uniprot id: W5Y0U9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1285583:CCASEI RS12630
gene id: 1285583:CCASEI_RS12630
uniprot id: W5XVN7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1285583:CCASEI RS02790
gene id: 1285583:CCASEI_RS02790
uniprot id: W5XR53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1285583:CCASEI RS03565
gene id: 1285583:CCASEI_RS03565
uniprot id: W5XRN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1285583:CCASEI RS03740
gene id: 1285583:CCASEI_RS03740
uniprot id: W5XRK5
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS00010
gene id: 1285583:CCASEI_RS00010
uniprot id: W5XPJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1285583:CCASEI RS08605
gene id: 1285583:CCASEI_RS08605
uniprot id: W5Y1D4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1285583:CCASEI RS09130
gene id: 1285583:CCASEI_RS09130
uniprot id: W5Y1S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1285583:CCASEI RS07955
gene id: 1285583:CCASEI_RS07955
uniprot id: W5XU24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1285583:CCASEI RS06670
gene id: 1285583:CCASEI_RS06670
uniprot id: W5XSP5
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

1285583:CCASEI RS12935
gene id: 1285583:CCASEI_RS12935
uniprot id: W5XW04
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS09175
gene id: 1285583:CCASEI_RS09175
uniprot id: W5XTX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

1285583:CCASEI RS09445
gene id: 1285583:CCASEI_RS09445
uniprot id: W5XUU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinone-dependent D-lactate dehydrogenase family.
messages: Catalyzes the oxidation of D-lactate to pyruvate.
messages: Cell membrane

1285583:CCASEI RS06720
gene id: 1285583:CCASEI_RS06720
uniprot id: W5XSQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1285583:CCASEI RS08420
gene id: 1285583:CCASEI_RS08420
uniprot id: W5XTE9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1285583:CCASEI RS12610
gene id: 1285583:CCASEI_RS12610
uniprot id: W5XVV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1285583:CCASEI RS00925
gene id: 1285583:CCASEI_RS00925
uniprot id: W5XQ28
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

1285583:CCASEI RS07495
gene id: 1285583:CCASEI_RS07495
uniprot id: W5XSY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1285583:CCASEI RS09395
gene id: 1285583:CCASEI_RS09395
uniprot id: W5XUT3
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the L-aspartate dehydrogenase family.
messages: Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
messages: The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia.

1285583:CCASEI RS09075
gene id: 1285583:CCASEI_RS09075
uniprot id: W5Y1R1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1285583:CCASEI RS10085
gene id: 1285583:CCASEI_RS10085
uniprot id: W5Y281
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS08400
gene id: 1285583:CCASEI_RS08400
uniprot id: W5XTJ4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1285583:CCASEI RS05805
gene id: 1285583:CCASEI_RS05805
uniprot id: W5XSS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1285583:CCASEI RS05395
gene id: 1285583:CCASEI_RS05395
uniprot id: W5XSJ0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1285583:CCASEI RS03130
gene id: 1285583:CCASEI_RS03130
uniprot id: W5XQM9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1285583:CCASEI RS07585
gene id: 1285583:CCASEI_RS07585
uniprot id: W5XTV3
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1285583:CCASEI RS12170
gene id: 1285583:CCASEI_RS12170
uniprot id: W5XVF3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1285583:CCASEI RS06215
gene id: 1285583:CCASEI_RS06215
uniprot id: W5XSB8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1285583:CCASEI RS02395
gene id: 1285583:CCASEI_RS02395
uniprot id: W5XQZ5
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS04185
gene id: 1285583:CCASEI_RS04185
uniprot id: W5XZ16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

1285583:CCASEI RS02705
gene id: 1285583:CCASEI_RS02705
uniprot id: W5XQE2
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS13860
gene id: 1285583:CCASEI_RS13860
uniprot id: W5XXB6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1285583:CCASEI RS01170
gene id: 1285583:CCASEI_RS01170
uniprot id: W5XQ80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1285583:CCASEI RS11160
gene id: 1285583:CCASEI_RS11160
uniprot id: W5Y2S5
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1285583:CCASEI RS05945
gene id: 1285583:CCASEI_RS05945
uniprot id: W5XZV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1285583:CCASEI RS04695
gene id: 1285583:CCASEI_RS04695
uniprot id: W5XSC2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1285583:CCASEI RS07395
gene id: 1285583:CCASEI_RS07395
uniprot id: W5XTM9
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1285583:CCASEI RS07185
gene id: 1285583:CCASEI_RS07185
uniprot id: W5Y0K7
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

1285583:CCASEI RS07795
gene id: 1285583:CCASEI_RS07795
uniprot id: W5XT76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1285583:CCASEI RS07550
gene id: 1285583:CCASEI_RS07550
uniprot id: W5XT40
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1285583:CCASEI RS11385
gene id: 1285583:CCASEI_RS11385
uniprot id: W5XVX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1285583:CCASEI RS00190
gene id: 1285583:CCASEI_RS00190
uniprot id: W5XNX4
names: Similarity
messages: Belongs to the AHA1 family.

1285583:CCASEI RS09290
gene id: 1285583:CCASEI_RS09290
uniprot id: W5Y1U4
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS03720
gene id: 1285583:CCASEI_RS03720
uniprot id: W5XQW7
names: Function
names: Similarity
messages: Belongs to the bacterial two-domain DSD family.
messages: Catalyzes the conversion of 3-dehydroshikimate to protocatechuate (3,4-dihydroxybenzoate), a common intermediate of quinate and shikimate degradation pathways.

1285583:CCASEI RS01250
gene id: 1285583:CCASEI_RS01250
uniprot id: W5XQ80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1285583:CCASEI RS04595
gene id: 1285583:CCASEI_RS04595
uniprot id: W5XSA6
names: Similarity
messages: Belongs to the Fur family.

1285583:CCASEI RS04665
gene id: 1285583:CCASEI_RS04665
uniprot id: W5XSB7
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1285583:CCASEI RS06725
gene id: 1285583:CCASEI_RS06725
uniprot id: W5Y0D0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1285583:CCASEI RS02930
gene id: 1285583:CCASEI_RS02930
uniprot id: W5XQI7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1285583:CCASEI RS05330
gene id: 1285583:CCASEI_RS05330
uniprot id: W5XRU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

1285583:CCASEI RS07485
gene id: 1285583:CCASEI_RS07485
uniprot id: W5XTT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1285583:CCASEI RS07725
gene id: 1285583:CCASEI_RS07725
uniprot id: W5Y0V6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1285583:CCASEI RS04775
gene id: 1285583:CCASEI_RS04775
uniprot id: W5XRI4
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1285583:CCASEI RS12645
gene id: 1285583:CCASEI_RS12645
uniprot id: W5XWM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1285583:CCASEI RS03855
gene id: 1285583:CCASEI_RS03855
uniprot id: W5XRW2
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1285583:CCASEI RS08675
gene id: 1285583:CCASEI_RS08675
uniprot id: W5Y1F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

1285583:CCASEI RS02430
gene id: 1285583:CCASEI_RS02430
uniprot id: W5XQ46
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS06070
gene id: 1285583:CCASEI_RS06070
uniprot id: W5XS86
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1285583:CCASEI RS05560
gene id: 1285583:CCASEI_RS05560
uniprot id: W5XRX4
names: Similarity
messages: Belongs to the asparaginase 1 family.

1285583:CCASEI RS09055
gene id: 1285583:CCASEI_RS09055
uniprot id: W5XUT1
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1285583:CCASEI RS05810
gene id: 1285583:CCASEI_RS05810
uniprot id: W5XS29
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1285583:CCASEI RS03275
gene id: 1285583:CCASEI_RS03275
uniprot id: W5XQK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1285583:CCASEI RS05895
gene id: 1285583:CCASEI_RS05895
uniprot id: W5XZU8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1285583:CCASEI RS05000
gene id: 1285583:CCASEI_RS05000
uniprot id: W5XZF1
names: Subcellular Location Annotation
messages: Secreted

1285583:CCASEI RS04305
gene id: 1285583:CCASEI_RS04305
uniprot id: W5XRC0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1285583:CCASEI RS09565
gene id: 1285583:CCASEI_RS09565
uniprot id: W5XV13
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1285583:CCASEI RS11020
gene id: 1285583:CCASEI_RS11020
uniprot id: W5XXF0
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1285583:CCASEI RS07430
gene id: 1285583:CCASEI_RS07430
uniprot id: W5Y0Q8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1285583:CCASEI RS06795
gene id: 1285583:CCASEI_RS06795
uniprot id: W5XSR8
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1285583:CCASEI RS11880
gene id: 1285583:CCASEI_RS11880
uniprot id: W5XVB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1285583:CCASEI RS02095
gene id: 1285583:CCASEI_RS02095
uniprot id: W5XPX8
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1285583:CCASEI RS10730
gene id: 1285583:CCASEI_RS10730
uniprot id: W5Y2J2
names: Similarity
messages: Belongs to the thymidylate kinase family.

1285583:CCASEI RS12265
gene id: 1285583:CCASEI_RS12265
uniprot id: W5XVH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1285583:CCASEI RS00585
gene id: 1285583:CCASEI_RS00585
uniprot id: W5XP69
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

1285583:CCASEI RS03040
gene id: 1285583:CCASEI_RS03040
uniprot id: W5XRA8
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1285583:CCASEI RS07630
gene id: 1285583:CCASEI_RS07630
uniprot id: W5Y0U4
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1285583:CCASEI RS10705
gene id: 1285583:CCASEI_RS10705
uniprot id: W5Y2J0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1285583:CCASEI RS06265
gene id: 1285583:CCASEI_RS06265
uniprot id: W5XSD1
names: Similarity
messages: Belongs to the PspA/IM30 family.

1285583:CCASEI RS09960
gene id: 1285583:CCASEI_RS09960
uniprot id: W5Y259
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1285583:CCASEI RS06145
gene id: 1285583:CCASEI_RS06145
uniprot id: W5XSA3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1285583:CCASEI RS03870
gene id: 1285583:CCASEI_RS03870
uniprot id: W5XR43
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS04470
gene id: 1285583:CCASEI_RS04470
uniprot id: W5XRE7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1285583:CCASEI RS06295
gene id: 1285583:CCASEI_RS06295
uniprot id: W5Y030
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1285583:CCASEI RS12590
gene id: 1285583:CCASEI_RS12590
uniprot id: W5Y3H7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1285583:CCASEI RS08340
gene id: 1285583:CCASEI_RS08340
uniprot id: W5XTD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1285583:CCASEI RS06000
gene id: 1285583:CCASEI_RS06000
uniprot id: W5XZW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1285583:CCASEI RS11985
gene id: 1285583:CCASEI_RS11985
uniprot id: W5XVJ7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1285583:CCASEI RS08445
gene id: 1285583:CCASEI_RS08445
uniprot id: W5XTF6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1285583:CCASEI RS04145
gene id: 1285583:CCASEI_RS04145
uniprot id: W5XRW4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1285583:CCASEI RS06285
gene id: 1285583:CCASEI_RS06285
uniprot id: W5XT33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1285583:CCASEI RS08010
gene id: 1285583:CCASEI_RS08010
uniprot id: W5XU35
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1285583:CCASEI RS05310
gene id: 1285583:CCASEI_RS05310
uniprot id: W5XZJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1285583:CCASEI RS12405
gene id: 1285583:CCASEI_RS12405
uniprot id: W5XWJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1285583:CCASEI RS06160
gene id: 1285583:CCASEI_RS06160
uniprot id: W5XT03
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS09975
gene id: 1285583:CCASEI_RS09975
uniprot id: W5XUA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1285583:CCASEI RS08865
gene id: 1285583:CCASEI_RS08865
uniprot id: W5XUG5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

1285583:CCASEI RS13395
gene id: 1285583:CCASEI_RS13395
uniprot id: W5XX15
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1285583:CCASEI RS12000
gene id: 1285583:CCASEI_RS12000
uniprot id: W5XWA7
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS03395
gene id: 1285583:CCASEI_RS03395
uniprot id: W5XRC6
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS06735
gene id: 1285583:CCASEI_RS06735
uniprot id: W5XTC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1285583:CCASEI RS09480
gene id: 1285583:CCASEI_RS09480
uniprot id: W5XU61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1285583:CCASEI RS06565
gene id: 1285583:CCASEI_RS06565
uniprot id: W5XSN2
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1285583:CCASEI RS08120
gene id: 1285583:CCASEI_RS08120
uniprot id: W5XU03
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS10990
gene id: 1285583:CCASEI_RS10990
uniprot id: W5XUR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1285583:CCASEI RS08555
gene id: 1285583:CCASEI_RS08555
uniprot id: W5Y1C3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1285583:CCASEI RS06100
gene id: 1285583:CCASEI_RS06100
uniprot id: W5XZZ0
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1285583:CCASEI RS03655
gene id: 1285583:CCASEI_RS03655
uniprot id: W5XQZ1
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1285583:CCASEI RS08800
gene id: 1285583:CCASEI_RS08800
uniprot id: W5XTS1
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS07875
gene id: 1285583:CCASEI_RS07875
uniprot id: W5XU08
names: Similarity
messages: Belongs to the universal stress protein A family.

1285583:CCASEI RS11555
gene id: 1285583:CCASEI_RS11555
uniprot id: W5XVC0
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1285583:CCASEI RS07265
gene id: 1285583:CCASEI_RS07265
uniprot id: W5XTQ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1285583:CCASEI RS03675
gene id: 1285583:CCASEI_RS03675
uniprot id: W5XQZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1285583:CCASEI RS13870
gene id: 1285583:CCASEI_RS13870
uniprot id: W5XWI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

1285583:CCASEI RS06750
gene id: 1285583:CCASEI_RS06750
uniprot id: W5Y0D3
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS02905
gene id: 1285583:CCASEI_RS02905
uniprot id: W5XQI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1285583:CCASEI RS04315
gene id: 1285583:CCASEI_RS04315
uniprot id: W5XS60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1285583:CCASEI RS00750
gene id: 1285583:CCASEI_RS00750
uniprot id: W5XPX3
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

1285583:CCASEI RS06350
gene id: 1285583:CCASEI_RS06350
uniprot id: W5XT92
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1285583:CCASEI RS03700
gene id: 1285583:CCASEI_RS03700
uniprot id: W5XR00
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1285583:CCASEI RS09100
gene id: 1285583:CCASEI_RS09100
uniprot id: W5Y1S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell membrane
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

1285583:CCASEI RS02255
gene id: 1285583:CCASEI_RS02255
uniprot id: W5XQS6
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1285583:CCASEI RS12865
gene id: 1285583:CCASEI_RS12865
uniprot id: W5Y3N2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1285583:CCASEI RS07285
gene id: 1285583:CCASEI_RS07285
uniprot id: W5XSZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1285583:CCASEI RS08655
gene id: 1285583:CCASEI_RS08655
uniprot id: W5Y1E4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1285583:CCASEI RS13840
gene id: 1285583:CCASEI_RS13840
uniprot id: W5XWB4
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

1285583:CCASEI RS06305
gene id: 1285583:CCASEI_RS06305
uniprot id: W5XT39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1285583:CCASEI RS07085
gene id: 1285583:CCASEI_RS07085
uniprot id: W5XTM2
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1285583:CCASEI RS07520
gene id: 1285583:CCASEI_RS07520
uniprot id: W5XSZ2
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1285583:CCASEI RS02330
gene id: 1285583:CCASEI_RS02330
uniprot id: W5XQ26
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1285583:CCASEI RS01795
gene id: 1285583:CCASEI_RS01795
uniprot id: W5XQJ2
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS06195
gene id: 1285583:CCASEI_RS06195
uniprot id: W5XSB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1285583:CCASEI RS00075
gene id: 1285583:CCASEI_RS00075
uniprot id: W5XNW2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1285583:CCASEI RS00150
gene id: 1285583:CCASEI_RS00150
uniprot id: W5XPL0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1285583:CCASEI RS10745
gene id: 1285583:CCASEI_RS10745
uniprot id: W5XUL3
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

1285583:CCASEI RS02895
gene id: 1285583:CCASEI_RS02895
uniprot id: W5XR31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1285583:CCASEI RS01835
gene id: 1285583:CCASEI_RS01835
uniprot id: W5XQP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

1285583:CCASEI RS08065
gene id: 1285583:CCASEI_RS08065
uniprot id: W5XU46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1285583:CCASEI RS02555
gene id: 1285583:CCASEI_RS02555
uniprot id: W5XQX9
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1285583:CCASEI RS07965
gene id: 1285583:CCASEI_RS07965
uniprot id: W5XT68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1285583:CCASEI RS11645
gene id: 1285583:CCASEI_RS11645
uniprot id: W5XW46
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1285583:CCASEI RS11235
gene id: 1285583:CCASEI_RS11235
uniprot id: W5XUW8
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1285583:CCASEI RS03580
gene id: 1285583:CCASEI_RS03580
uniprot id: W5XQX5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1285583:CCASEI RS05055
gene id: 1285583:CCASEI_RS05055
uniprot id: W5XSH0
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1285583:CCASEI RS02065
gene id: 1285583:CCASEI_RS02065
uniprot id: W5XQP0
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1285583:CCASEI RS11380
gene id: 1285583:CCASEI_RS11380
uniprot id: W5XW00
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1285583:CCASEI RS15345
gene id: 1285583:CCASEI_RS15345
uniprot id: W5XTP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1285583:CCASEI RS02840
gene id: 1285583:CCASEI_RS02840
uniprot id: W5XYA3
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS04360
gene id: 1285583:CCASEI_RS04360
uniprot id: W5XZ41
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1285583:CCASEI RS08690
gene id: 1285583:CCASEI_RS08690
uniprot id: W5XTL8
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS04800
gene id: 1285583:CCASEI_RS04800
uniprot id: W5XRI9
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1285583:CCASEI RS08590
gene id: 1285583:CCASEI_RS08590
uniprot id: W5XU99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1285583:CCASEI RS03505
gene id: 1285583:CCASEI_RS03505
uniprot id: W5XQW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1285583:CCASEI RS02825
gene id: 1285583:CCASEI_RS02825
uniprot id: W5XQB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1285583:CCASEI RS01235
gene id: 1285583:CCASEI_RS01235
uniprot id: W5XXF0
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1285583:CCASEI RS05845
gene id: 1285583:CCASEI_RS05845
uniprot id: W5XZT9
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS02885
gene id: 1285583:CCASEI_RS02885
uniprot id: W5XYB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1285583:CCASEI RS09795
gene id: 1285583:CCASEI_RS09795
uniprot id: W5XV48
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS10290
gene id: 1285583:CCASEI_RS10290
uniprot id: W5Y2B7
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

1285583:CCASEI RS14015
gene id: 1285583:CCASEI_RS14015
uniprot id: W5XWF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1285583:CCASEI RS06845
gene id: 1285583:CCASEI_RS06845
uniprot id: W5XSS6
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1285583:CCASEI RS10920
gene id: 1285583:CCASEI_RS10920
uniprot id: W5XUW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1285583:CCASEI RS12980
gene id: 1285583:CCASEI_RS12980
uniprot id: W5XVV3
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

1285583:CCASEI RS07025
gene id: 1285583:CCASEI_RS07025
uniprot id: W5XSV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1285583:CCASEI RS03110
gene id: 1285583:CCASEI_RS03110
uniprot id: W5XYF3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

1285583:CCASEI RS14115
gene id: 1285583:CCASEI_RS14115
uniprot id: W5XXH8
names: Similarity
messages: Belongs to the ParB family.

1285583:CCASEI RS02500
gene id: 1285583:CCASEI_RS02500
uniprot id: W5XR10
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

1285583:CCASEI RS12490
gene id: 1285583:CCASEI_RS12490
uniprot id: W5Y3F8
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS08320
gene id: 1285583:CCASEI_RS08320
uniprot id: W5XTH9
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1285583:CCASEI RS06025
gene id: 1285583:CCASEI_RS06025
uniprot id: W5XZX5
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1285583:CCASEI RS06470
gene id: 1285583:CCASEI_RS06470
uniprot id: W5XTD1
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1285583:CCASEI RS13295
gene id: 1285583:CCASEI_RS13295
uniprot id: W5XX07
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

1285583:CCASEI RS02450
gene id: 1285583:CCASEI_RS02450
uniprot id: W5XR02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1285583:CCASEI RS04220
gene id: 1285583:CCASEI_RS04220
uniprot id: W5XRX6
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

1285583:CCASEI RS02080
gene id: 1285583:CCASEI_RS02080
uniprot id: W5XXW5
names: Similarity
messages: Belongs to the peptidase M1 family.

1285583:CCASEI RS11375
gene id: 1285583:CCASEI_RS11375
uniprot id: W5Y2W3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1285583:CCASEI RS10925
gene id: 1285583:CCASEI_RS10925
uniprot id: W5Y2N3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1285583:CCASEI RS08890
gene id: 1285583:CCASEI_RS08890
uniprot id: W5XUH0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.

1285583:CCASEI RS12965
gene id: 1285583:CCASEI_RS12965
uniprot id: W5Y3P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1285583:CCASEI RS03705
gene id: 1285583:CCASEI_RS03705
uniprot id: W5XYS3
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1285583:CCASEI RS07095
gene id: 1285583:CCASEI_RS07095
uniprot id: W5XSS4
names: Similarity
messages: Belongs to the AHA1 family.

1285583:CCASEI RS10595
gene id: 1285583:CCASEI_RS10595
uniprot id: W5XVF5
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1285583:CCASEI RS12295
gene id: 1285583:CCASEI_RS12295
uniprot id: W5XVP5
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1285583:CCASEI RS10760
gene id: 1285583:CCASEI_RS10760
uniprot id: W5XVN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1285583:CCASEI RS06300
gene id: 1285583:CCASEI_RS06300
uniprot id: W5XT63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1285583:CCASEI RS14350
gene id: 1285583:CCASEI_RS14350
uniprot id: W5XYY6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1285583:CCASEI RS04190
gene id: 1285583:CCASEI_RS04190
uniprot id: W5XS39
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

1285583:CCASEI RS05155
gene id: 1285583:CCASEI_RS05155
uniprot id: W5XZG9
names: Similarity
messages: Belongs to the glutamine synthetase family.

1285583:CCASEI RS13075
gene id: 1285583:CCASEI_RS13075
uniprot id: W5XWU9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

1285583:CCASEI RS12300
gene id: 1285583:CCASEI_RS12300
uniprot id: W5Y3C5
names: Similarity
messages: Belongs to the GARS family.

1285583:CCASEI RS03355
gene id: 1285583:CCASEI_RS03355
uniprot id: W5XQS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1285583:CCASEI RS11180
gene id: 1285583:CCASEI_RS11180
uniprot id: W5XV15
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1285583:CCASEI RS06705
gene id: 1285583:CCASEI_RS06705
uniprot id: W5XTG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

1285583:CCASEI RS07830
gene id: 1285583:CCASEI_RS07830
uniprot id: W5XTZ7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1285583:CCASEI RS01790
gene id: 1285583:CCASEI_RS01790
uniprot id: W5XQN6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1285583:CCASEI RS11990
gene id: 1285583:CCASEI_RS11990
uniprot id: W5Y388
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1285583:CCASEI RS06855
gene id: 1285583:CCASEI_RS06855
uniprot id: W5XTI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1285583:CCASEI RS06245
gene id: 1285583:CCASEI_RS06245
uniprot id: W5XSC7
names: Similarity
messages: Belongs to the YciI family.

1285583:CCASEI RS12330
gene id: 1285583:CCASEI_RS12330
uniprot id: W5XWI0
names: Similarity
messages: Belongs to the TPP enzyme family.

1285583:CCASEI RS05580
gene id: 1285583:CCASEI_RS05580
uniprot id: W5XRX8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1285583:CCASEI RS02415
gene id: 1285583:CCASEI_RS02415
uniprot id: W5XY29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Fes family.
messages: Cytoplasm

1285583:CCASEI RS04935
gene id: 1285583:CCASEI_RS04935
uniprot id: W5XSA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1285583:CCASEI RS03150
gene id: 1285583:CCASEI_RS03150
uniprot id: W5XQH2
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

1285583:CCASEI RS07990
gene id: 1285583:CCASEI_RS07990
uniprot id: W5XT73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1285583:CCASEI RS12205
gene id: 1285583:CCASEI_RS12205
uniprot id: W5Y3B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1285583:CCASEI RS06010
gene id: 1285583:CCASEI_RS06010
uniprot id: W5XSW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1285583:CCASEI RS10965
gene id: 1285583:CCASEI_RS10965
uniprot id: W5XUR3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1285583:CCASEI RS03190
gene id: 1285583:CCASEI_RS03190
uniprot id: W5XRD6
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS05250
gene id: 1285583:CCASEI_RS05250
uniprot id: W5XRR7
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

1285583:CCASEI RS03895
gene id: 1285583:CCASEI_RS03895
uniprot id: W5XRY2
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1285583:CCASEI RS07590
gene id: 1285583:CCASEI_RS07590
uniprot id: W5XTR5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1285583:CCASEI RS03480
gene id: 1285583:CCASEI_RS03480
uniprot id: W5XQV4
names: Function
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.

1285583:CCASEI RS09110
gene id: 1285583:CCASEI_RS09110
uniprot id: W5XUN9
names: Function
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

1285583:CCASEI RS05625
gene id: 1285583:CCASEI_RS05625
uniprot id: W5XSN5
names: Similarity
messages: Belongs to the IMPACT family.

1285583:CCASEI RS08600
gene id: 1285583:CCASEI_RS08600
uniprot id: W5XTN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1285583:CCASEI RS11945
gene id: 1285583:CCASEI_RS11945
uniprot id: W5XW99
names: Similarity
messages: Belongs to the phosphosulfolactate synthase family.

1285583:CCASEI RS08355
gene id: 1285583:CCASEI_RS08355
uniprot id: W5XUA3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1285583:CCASEI RS05900
gene id: 1285583:CCASEI_RS05900
uniprot id: W5XSX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1285583:CCASEI RS00915
gene id: 1285583:CCASEI_RS00915
uniprot id: W5XPE2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1285583:CCASEI RS03665
gene id: 1285583:CCASEI_RS03665
uniprot id: W5XRP9
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS05550
gene id: 1285583:CCASEI_RS05550
uniprot id: W5XSL9
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

1285583:CCASEI RS02360
gene id: 1285583:CCASEI_RS02360
uniprot id: W5XQ87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. Mmr subfamily.
messages: Cell membrane
messages: Membrane

1285583:CCASEI RS13090
gene id: 1285583:CCASEI_RS13090
uniprot id: W5Y3S1
names: Subcellular Location Annotation
messages: Membrane

1285583:CCASEI RS07385
gene id: 1285583:CCASEI_RS07385
uniprot id: W5Y0P8
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1285583:CCASEI RS02980
gene id: 1285583:CCASEI_RS02980
uniprot id: W5XQJ8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.