1276227:SCHRY RS05160
gene id: 1276227:SCHRY_RS05160
uniprot id: R4UJU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1276227:SCHRY RS03840
gene id: 1276227:SCHRY_RS03840
uniprot id: R4UBP7
names: Subcellular Location Annotation
messages: Membrane

1276227:SCHRY RS03925
gene id: 1276227:SCHRY_RS03925
uniprot id: R4UJ48
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1276227:SCHRY RS05210
gene id: 1276227:SCHRY_RS05210
uniprot id: R4UJW1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1276227:SCHRY RS03500
gene id: 1276227:SCHRY_RS03500
uniprot id: R4U1R9
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1276227:SCHRY RS03990
gene id: 1276227:SCHRY_RS03990
uniprot id: R4U1Z3
names: Subcellular Location Annotation
messages: Membrane

1276227:SCHRY RS01640
gene id: 1276227:SCHRY_RS01640
uniprot id: R4UAG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1276227:SCHRY RS01850
gene id: 1276227:SCHRY_RS01850
uniprot id: R4UFL1
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

1276227:SCHRY RS00935
gene id: 1276227:SCHRY_RS00935
uniprot id: R4UHG5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276227:SCHRY RS05015
gene id: 1276227:SCHRY_RS05015
uniprot id: R4U2F8
names: Subcellular Location Annotation
messages: Membrane

1276227:SCHRY RS00025
gene id: 1276227:SCHRY_RS00025
uniprot id: R4U038
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276227:SCHRY RS02270
gene id: 1276227:SCHRY_RS02270
uniprot id: R4U3E8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276227:SCHRY RS01270
gene id: 1276227:SCHRY_RS01270
uniprot id: R4UFC0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276227:SCHRY RS01615
gene id: 1276227:SCHRY_RS01615
uniprot id: R4UAG1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276227:SCHRY RS00965
gene id: 1276227:SCHRY_RS00965
uniprot id: R4UF71
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1276227:SCHRY RS04260
gene id: 1276227:SCHRY_RS04260
uniprot id: R4UJB6
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1276227:SCHRY RS02120
gene id: 1276227:SCHRY_RS02120
uniprot id: R4U3B9
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1276227:SCHRY RS01005
gene id: 1276227:SCHRY_RS01005
uniprot id: R4U2S1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1276227:SCHRY RS00465
gene id: 1276227:SCHRY_RS00465
uniprot id: R4U2K8
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

1276227:SCHRY RS02745
gene id: 1276227:SCHRY_RS02745
uniprot id: R4U3N4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1276227:SCHRY RS00650
gene id: 1276227:SCHRY_RS00650
uniprot id: R4UF25
names: Subcellular Location Annotation
messages: Membrane

1276227:SCHRY RS02225
gene id: 1276227:SCHRY_RS02225
uniprot id: R4UAS9
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1276227:SCHRY RS03270
gene id: 1276227:SCHRY_RS03270
uniprot id: R4UIT8
names: Subcellular Location Annotation
messages: Membrane

1276227:SCHRY RS00615
gene id: 1276227:SCHRY_RS00615
uniprot id: R4U2M6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1276227:SCHRY RS03815
gene id: 1276227:SCHRY_RS03815
uniprot id: R4UBP1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1276227:SCHRY RS00560
gene id: 1276227:SCHRY_RS00560
uniprot id: R4U0E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1276227:SCHRY RS04840
gene id: 1276227:SCHRY_RS04840
uniprot id: R4UJN4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1276227:SCHRY RS01155
gene id: 1276227:SCHRY_RS01155
uniprot id: R4U2U9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1276227:SCHRY RS04210
gene id: 1276227:SCHRY_RS04210
uniprot id: R4UJA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

1276227:SCHRY RS02595
gene id: 1276227:SCHRY_RS02595
uniprot id: R4U3K7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase family. ParE type 2 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1276227:SCHRY RS00050
gene id: 1276227:SCHRY_RS00050
uniprot id: R4UGY8
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1276227:SCHRY RS02450
gene id: 1276227:SCHRY_RS02450
uniprot id: R4UFY1
names: Similarity
messages: Belongs to the TlyA family.

1276227:SCHRY RS01930
gene id: 1276227:SCHRY_RS01930
uniprot id: R4UFM5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1276227:SCHRY RS01095
gene id: 1276227:SCHRY_RS01095
uniprot id: R4UHJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1276227:SCHRY RS03120
gene id: 1276227:SCHRY_RS03120
uniprot id: R4U1K7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1276227:SCHRY RS03960
gene id: 1276227:SCHRY_RS03960
uniprot id: R4U1Y8
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1276227:SCHRY RS03615
gene id: 1276227:SCHRY_RS03615
uniprot id: R4UGM9
names: Subcellular Location Annotation
messages: Membrane

1276227:SCHRY RS00275
gene id: 1276227:SCHRY_RS00275
uniprot id: R4U0A3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1276227:SCHRY RS01565
gene id: 1276227:SCHRY_RS01565
uniprot id: R4UAF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1276227:SCHRY RS00810
gene id: 1276227:SCHRY_RS00810
uniprot id: R4UHE0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

1276227:SCHRY RS00995
gene id: 1276227:SCHRY_RS00995
uniprot id: R4UHH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1276227:SCHRY RS04880
gene id: 1276227:SCHRY_RS04880
uniprot id: R4UH75
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1276227:SCHRY RS03760
gene id: 1276227:SCHRY_RS03760
uniprot id: R4UGQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.

1276227:SCHRY RS00860
gene id: 1276227:SCHRY_RS00860
uniprot id: R4UHF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

1276227:SCHRY RS00515
gene id: 1276227:SCHRY_RS00515
uniprot id: R4U2L4
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

1276227:SCHRY RS00235
gene id: 1276227:SCHRY_RS00235
uniprot id: R4U9W5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1276227:SCHRY RS02545
gene id: 1276227:SCHRY_RS02545
uniprot id: R4U3J8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1276227:SCHRY RS00835
gene id: 1276227:SCHRY_RS00835
uniprot id: R4UHE6
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1276227:SCHRY RS00990
gene id: 1276227:SCHRY_RS00990
uniprot id: R4UF76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1276227:SCHRY RS01535
gene id: 1276227:SCHRY_RS01535
uniprot id: R4U322
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1276227:SCHRY RS04160
gene id: 1276227:SCHRY_RS04160
uniprot id: R4U223
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1276227:SCHRY RS02915
gene id: 1276227:SCHRY_RS02915
uniprot id: R4UGC0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1276227:SCHRY RS03255
gene id: 1276227:SCHRY_RS03255
uniprot id: R4U3X3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1276227:SCHRY RS03275
gene id: 1276227:SCHRY_RS03275
uniprot id: R4U1N2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1276227:SCHRY RS01865
gene id: 1276227:SCHRY_RS01865
uniprot id: R4U381
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1276227:SCHRY RS03850
gene id: 1276227:SCHRY_RS03850
uniprot id: R4UJ43
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276227:SCHRY RS02175
gene id: 1276227:SCHRY_RS02175
uniprot id: R4UAR9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1276227:SCHRY RS04270
gene id: 1276227:SCHRY_RS04270
uniprot id: R4U4B3
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1276227:SCHRY RS03355
gene id: 1276227:SCHRY_RS03355
uniprot id: R4U3Y2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

1276227:SCHRY RS01135
gene id: 1276227:SCHRY_RS01135
uniprot id: R4UA89
names: Subcellular Location Annotation
messages: Membrane

1276227:SCHRY RS02750
gene id: 1276227:SCHRY_RS02750
uniprot id: R4UB42
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1276227:SCHRY RS00830
gene id: 1276227:SCHRY_RS00830
uniprot id: R4UF52
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1276227:SCHRY RS02925
gene id: 1276227:SCHRY_RS02925
uniprot id: R4U3T1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1276227:SCHRY RS01215
gene id: 1276227:SCHRY_RS01215
uniprot id: R4UA98
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1276227:SCHRY RS04905
gene id: 1276227:SCHRY_RS04905
uniprot id: R4UH82
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1276227:SCHRY RS04985
gene id: 1276227:SCHRY_RS04985
uniprot id: R4UJR6
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276227:SCHRY RS03680
gene id: 1276227:SCHRY_RS03680
uniprot id: R4UBM1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecU family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation.

1276227:SCHRY RS01245
gene id: 1276227:SCHRY_RS01245
uniprot id: R4UFB7
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1276227:SCHRY RS00290
gene id: 1276227:SCHRY_RS00290
uniprot id: R4UEX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1276227:SCHRY RS02215
gene id: 1276227:SCHRY_RS02215
uniprot id: R4U120
names: Subcellular Location Annotation
messages: Membrane

1276227:SCHRY RS02780
gene id: 1276227:SCHRY_RS02780
uniprot id: R4UG90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1276227:SCHRY RS00640
gene id: 1276227:SCHRY_RS00640
uniprot id: R4U2M9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1276227:SCHRY RS03285
gene id: 1276227:SCHRY_RS03285
uniprot id: R4UBF7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1276227:SCHRY RS03835
gene id: 1276227:SCHRY_RS03835
uniprot id: R4U458
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

1276227:SCHRY RS00070
gene id: 1276227:SCHRY_RS00070
uniprot id: R4UEN9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1276227:SCHRY RS02265
gene id: 1276227:SCHRY_RS02265
uniprot id: R4U129
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1276227:SCHRY RS04580
gene id: 1276227:SCHRY_RS04580
uniprot id: R4U287
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1276227:SCHRY RS01505
gene id: 1276227:SCHRY_RS01505
uniprot id: R4U0S5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1276227:SCHRY RS05200
gene id: 1276227:SCHRY_RS05200
uniprot id: R4UCH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1276227:SCHRY RS03130
gene id: 1276227:SCHRY_RS03130
uniprot id: R4UBD1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1276227:SCHRY RS01660
gene id: 1276227:SCHRY_RS01660
uniprot id: R4U345
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1276227:SCHRY RS03915
gene id: 1276227:SCHRY_RS03915
uniprot id: R4UBQ1
names: Similarity
messages: Belongs to the asp23 family.

1276227:SCHRY RS02135
gene id: 1276227:SCHRY_RS02135
uniprot id: R4UI54
names: Subcellular Location Annotation
messages: Membrane

1276227:SCHRY RS04010
gene id: 1276227:SCHRY_RS04010
uniprot id: R4UJ67
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1276227:SCHRY RS01610
gene id: 1276227:SCHRY_RS01610
uniprot id: R4U336
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1276227:SCHRY RS02530
gene id: 1276227:SCHRY_RS02530
uniprot id: R4UFZ9
names: Subcellular Location Annotation
messages: Membrane

1276227:SCHRY RS02875
gene id: 1276227:SCHRY_RS02875
uniprot id: R4U3S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

1276227:SCHRY RS02280
gene id: 1276227:SCHRY_RS02280
uniprot id: R4UFT7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1276227:SCHRY RS04025
gene id: 1276227:SCHRY_RS04025
uniprot id: R4UBR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1276227:SCHRY RS01290
gene id: 1276227:SCHRY_RS01290
uniprot id: R4UAA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1276227:SCHRY RS01835
gene id: 1276227:SCHRY_RS01835
uniprot id: R4U0W9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1276227:SCHRY RS05110
gene id: 1276227:SCHRY_RS05110
uniprot id: R4UJT9
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1276227:SCHRY RS00585
gene id: 1276227:SCHRY_RS00585
uniprot id: R4U0E4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1276227:SCHRY RS01705
gene id: 1276227:SCHRY_RS01705
uniprot id: R4U0V5
names: Subcellular Location Annotation
messages: Membrane

1276227:SCHRY RS05100
gene id: 1276227:SCHRY_RS05100
uniprot id: R4UCF4
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1276227:SCHRY RS04505
gene id: 1276227:SCHRY_RS04505
uniprot id: R4U4F8
names: Subcellular Location Annotation
messages: Membrane

1276227:SCHRY RS03010
gene id: 1276227:SCHRY_RS03010
uniprot id: R4UGD7
names: Function
names: Similarity
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.

1276227:SCHRY RS00505
gene id: 1276227:SCHRY_RS00505
uniprot id: R4UH84
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1276227:SCHRY RS00040
gene id: 1276227:SCHRY_RS00040
uniprot id: R4U9Q1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1276227:SCHRY RS04955
gene id: 1276227:SCHRY_RS04955
uniprot id: R4UH93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1276227:SCHRY RS00930
gene id: 1276227:SCHRY_RS00930
uniprot id: R4UF69
names: Subcellular Location Annotation
messages: Membrane

1276227:SCHRY RS01370
gene id: 1276227:SCHRY_RS01370
uniprot id: R4UFD6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1276227:SCHRY RS02670
gene id: 1276227:SCHRY_RS02670
uniprot id: R4U3M1
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Homodimer.

1276227:SCHRY RS02645
gene id: 1276227:SCHRY_RS02645
uniprot id: R4U3L7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1276227:SCHRY RS03175
gene id: 1276227:SCHRY_RS03175
uniprot id: R4U1L4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1276227:SCHRY RS00085
gene id: 1276227:SCHRY_RS00085
uniprot id: R4U2C9
names: Subcellular Location Annotation
messages: Membrane

1276227:SCHRY RS01375
gene id: 1276227:SCHRY_RS01375
uniprot id: R4UHQ0
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1276227:SCHRY RS04965
gene id: 1276227:SCHRY_RS04965
uniprot id: R4U2F2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276227:SCHRY RS04410
gene id: 1276227:SCHRY_RS04410
uniprot id: R4U261
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1276227:SCHRY RS01015
gene id: 1276227:SCHRY_RS01015
uniprot id: R4UF81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1276227:SCHRY RS01795
gene id: 1276227:SCHRY_RS01795
uniprot id: R4UAK0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1276227:SCHRY RS02430
gene id: 1276227:SCHRY_RS02430
uniprot id: R4UIB5
names: Subcellular Location Annotation
messages: Membrane

1276227:SCHRY RS01405
gene id: 1276227:SCHRY_RS01405
uniprot id: R4U0R1
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1276227:SCHRY RS03350
gene id: 1276227:SCHRY_RS03350
uniprot id: R4U1P4
names: Subcellular Location Annotation
messages: Membrane

1276227:SCHRY RS00880
gene id: 1276227:SCHRY_RS00880
uniprot id: R4UF60
names: Similarity
messages: Belongs to the DEAD box helicase family.

1276227:SCHRY RS02220
gene id: 1276227:SCHRY_RS02220
uniprot id: R4U3D8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1276227:SCHRY RS03345
gene id: 1276227:SCHRY_RS03345
uniprot id: R4UIV2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1276227:SCHRY RS01020
gene id: 1276227:SCHRY_RS01020
uniprot id: R4UHI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1276227:SCHRY RS01040
gene id: 1276227:SCHRY_RS01040
uniprot id: R4UF85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1276227:SCHRY RS04130
gene id: 1276227:SCHRY_RS04130
uniprot id: R4UJ95
names: Similarity
messages: Belongs to the thioredoxin family.

1276227:SCHRY RS02095
gene id: 1276227:SCHRY_RS02095
uniprot id: R4U3B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1276227:SCHRY RS05135
gene id: 1276227:SCHRY_RS05135
uniprot id: R4UJU4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Belongs to the heat shock protein 70 family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276227:SCHRY RS04240
gene id: 1276227:SCHRY_RS04240
uniprot id: R4U231
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1276227:SCHRY RS05215
gene id: 1276227:SCHRY_RS05215
uniprot id: R4UAF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1276227:SCHRY RS01475
gene id: 1276227:SCHRY_RS01475
uniprot id: R4UHS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1276227:SCHRY RS00280
gene id: 1276227:SCHRY_RS00280
uniprot id: R4U2I3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1276227:SCHRY RS03040
gene id: 1276227:SCHRY_RS03040
uniprot id: R4UGE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1276227:SCHRY RS02025
gene id: 1276227:SCHRY_RS02025
uniprot id: R4U0Z1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276227:SCHRY RS01540
gene id: 1276227:SCHRY_RS01540
uniprot id: R4UAE7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1276227:SCHRY RS01225
gene id: 1276227:SCHRY_RS01225
uniprot id: R4UHL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

1276227:SCHRY RS03320
gene id: 1276227:SCHRY_RS03320
uniprot id: R4UIU7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1276227:SCHRY RS00555
gene id: 1276227:SCHRY_RS00555
uniprot id: R4UH92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1276227:SCHRY RS03325
gene id: 1276227:SCHRY_RS03325
uniprot id: R4U1N9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1276227:SCHRY RS00005
gene id: 1276227:SCHRY_RS00005
uniprot id: R4U2B7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1276227:SCHRY RS01170
gene id: 1276227:SCHRY_RS01170
uniprot id: R4UHK9
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

1276227:SCHRY RS05105
gene id: 1276227:SCHRY_RS05105
uniprot id: R4UHD3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1276227:SCHRY RS02075
gene id: 1276227:SCHRY_RS02075
uniprot id: R4UAP6
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

1276227:SCHRY RS02550
gene id: 1276227:SCHRY_RS02550
uniprot id: R4UAZ8
names: Subcellular Location Annotation
messages: Membrane

1276227:SCHRY RS03400
gene id: 1276227:SCHRY_RS03400
uniprot id: R4U1Q2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

1276227:SCHRY RS04950
gene id: 1276227:SCHRY_RS04950
uniprot id: R4UCC2
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1276227:SCHRY RS00455
gene id: 1276227:SCHRY_RS00455
uniprot id: R4UH76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1276227:SCHRY RS04780
gene id: 1276227:SCHRY_RS04780
uniprot id: R4UH55
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1276227:SCHRY RS03140
gene id: 1276227:SCHRY_RS03140
uniprot id: R4UIR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1276227:SCHRY RS05120
gene id: 1276227:SCHRY_RS05120
uniprot id: R4U4U2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1276227:SCHRY RS04735
gene id: 1276227:SCHRY_RS04735
uniprot id: R4UH45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

1276227:SCHRY RS01650
gene id: 1276227:SCHRY_RS01650
uniprot id: R4UHW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1276227:SCHRY RS00645
gene id: 1276227:SCHRY_RS00645
uniprot id: R4UA21
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1276227:SCHRY RS01120
gene id: 1276227:SCHRY_RS01120
uniprot id: R4UHK1
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1276227:SCHRY RS02090
gene id: 1276227:SCHRY_RS02090
uniprot id: R4U100
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1276227:SCHRY RS04765
gene id: 1276227:SCHRY_RS04765
uniprot id: R4U2C3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1276227:SCHRY RS01915
gene id: 1276227:SCHRY_RS01915
uniprot id: R4U0X9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276227:SCHRY RS01345
gene id: 1276227:SCHRY_RS01345
uniprot id: R4UFD3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1276227:SCHRY RS02610
gene id: 1276227:SCHRY_RS02610
uniprot id: R4UIF0
names: Subcellular Location Annotation
messages: Membrane

1276227:SCHRY RS00915
gene id: 1276227:SCHRY_RS00915
uniprot id: R4U0I9
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

1276227:SCHRY RS03225
gene id: 1276227:SCHRY_RS03225
uniprot id: R4U1M3
names: Similarity
messages: Belongs to the pyruvate kinase family.

1276227:SCHRY RS03420
gene id: 1276227:SCHRY_RS03420
uniprot id: R4UIW5
names: Subcellular Location Annotation
messages: Membrane

1276227:SCHRY RS01000
gene id: 1276227:SCHRY_RS01000
uniprot id: R4U0K1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1276227:SCHRY RS01525
gene id: 1276227:SCHRY_RS01525
uniprot id: R4UHT4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1276227:SCHRY RS04835
gene id: 1276227:SCHRY_RS04835
uniprot id: R4UH64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1276227:SCHRY RS01045
gene id: 1276227:SCHRY_RS01045
uniprot id: R4UHI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1276227:SCHRY RS00600
gene id: 1276227:SCHRY_RS00600
uniprot id: R4UF16
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1276227:SCHRY RS01200
gene id: 1276227:SCHRY_RS01200
uniprot id: R4UHL5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1276227:SCHRY RS02590
gene id: 1276227:SCHRY_RS02590
uniprot id: R4U177
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1276227:SCHRY RS03340
gene id: 1276227:SCHRY_RS03340
uniprot id: R4UGI6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1276227:SCHRY RS03690
gene id: 1276227:SCHRY_RS03690
uniprot id: R4UJ15
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1276227:SCHRY RS01050
gene id: 1276227:SCHRY_RS01050
uniprot id: R4U0K7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1276227:SCHRY RS01355
gene id: 1276227:SCHRY_RS01355
uniprot id: R4U0Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Membrane

1276227:SCHRY RS01875
gene id: 1276227:SCHRY_RS01875
uniprot id: R4UFL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1276227:SCHRY RS00015
gene id: 1276227:SCHRY_RS00015
uniprot id: R4UEM7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1276227:SCHRY RS00130
gene id: 1276227:SCHRY_RS00130
uniprot id: R4U058
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276227:SCHRY RS02765
gene id: 1276227:SCHRY_RS02765
uniprot id: R4U1B4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1276227:SCHRY RS03230
gene id: 1276227:SCHRY_RS03230
uniprot id: R4U3W9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276227:SCHRY RS03995
gene id: 1276227:SCHRY_RS03995
uniprot id: R4U474
names: Subcellular Location Annotation
messages: Membrane

1276227:SCHRY RS02555
gene id: 1276227:SCHRY_RS02555
uniprot id: R4UG06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1276227:SCHRY RS00485
gene id: 1276227:SCHRY_RS00485
uniprot id: R4U0C9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

1276227:SCHRY RS01665
gene id: 1276227:SCHRY_RS01665
uniprot id: R4UAH4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1276227:SCHRY RS00985
gene id: 1276227:SCHRY_RS00985
uniprot id: R4UA69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1276227:SCHRY RS01105
gene id: 1276227:SCHRY_RS01105
uniprot id: R4U2U0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1276227:SCHRY RS02620
gene id: 1276227:SCHRY_RS02620
uniprot id: R4U3L1
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1276227:SCHRY RS01230
gene id: 1276227:SCHRY_RS01230
uniprot id: R4U0N5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1276227:SCHRY RS04275
gene id: 1276227:SCHRY_RS04275
uniprot id: R4UBV8
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1276227:SCHRY RS01110
gene id: 1276227:SCHRY_RS01110
uniprot id: R4UA85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1276227:SCHRY RS02360
gene id: 1276227:SCHRY_RS02360
uniprot id: R4U146
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1276227:SCHRY RS05090
gene id: 1276227:SCHRY_RS05090
uniprot id: R4U2H2
names: Subcellular Location Annotation
messages: Membrane

1276227:SCHRY RS01685
gene id: 1276227:SCHRY_RS01685
uniprot id: R4U350
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1276227:SCHRY RS01840
gene id: 1276227:SCHRY_RS01840
uniprot id: R4U377
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1276227:SCHRY RS00110
gene id: 1276227:SCHRY_RS00110
uniprot id: R4U2D4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1276227:SCHRY RS01395
gene id: 1276227:SCHRY_RS01395
uniprot id: R4UFE0
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1276227:SCHRY RS03095
gene id: 1276227:SCHRY_RS03095
uniprot id: R4UIQ5
names: Subcellular Location Annotation
messages: Membrane

1276227:SCHRY RS03030
gene id: 1276227:SCHRY_RS03030
uniprot id: R4UBB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1276227:SCHRY RS00395
gene id: 1276227:SCHRY_RS00395
uniprot id: R4UEY6
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1276227:SCHRY RS03970
gene id: 1276227:SCHRY_RS03970
uniprot id: R4UBQ9
names: Subcellular Location Annotation
messages: Membrane

1276227:SCHRY RS03135
gene id: 1276227:SCHRY_RS03135
uniprot id: R4UGF4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1276227:SCHRY RS00745
gene id: 1276227:SCHRY_RS00745
uniprot id: R4U2P1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

1276227:SCHRY RS00020
gene id: 1276227:SCHRY_RS00020
uniprot id: R4UGY2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1276227:SCHRY RS00825
gene id: 1276227:SCHRY_RS00825
uniprot id: R4UA48
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276227:SCHRY RS03085
gene id: 1276227:SCHRY_RS03085
uniprot id: R4UBC4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1276227:SCHRY RS01205
gene id: 1276227:SCHRY_RS01205
uniprot id: R4U0N0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1276227:SCHRY RS00225
gene id: 1276227:SCHRY_RS00225
uniprot id: R4UH46
names: Subcellular Location Annotation
messages: Membrane

1276227:SCHRY RS03740
gene id: 1276227:SCHRY_RS03740
uniprot id: R4UJ24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1276227:SCHRY RS01905
gene id: 1276227:SCHRY_RS01905
uniprot id: R4UFL9
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1276227:SCHRY RS04265
gene id: 1276227:SCHRY_RS04265
uniprot id: R4U236
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1276227:SCHRY RS00295
gene id: 1276227:SCHRY_RS00295
uniprot id: R4UH56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1276227:SCHRY RS02640
gene id: 1276227:SCHRY_RS02640
uniprot id: R4U185
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

1276227:SCHRY RS00620
gene id: 1276227:SCHRY_RS00620
uniprot id: R4UA18
names: Similarity
messages: Belongs to the HPrK/P family.

1276227:SCHRY RS00925
gene id: 1276227:SCHRY_RS00925
uniprot id: R4UA61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).

1276227:SCHRY RS02600
gene id: 1276227:SCHRY_RS02600
uniprot id: R4UB07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1276227:SCHRY RS00765
gene id: 1276227:SCHRY_RS00765
uniprot id: R4U0G8
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1276227:SCHRY RS00610
gene id: 1276227:SCHRY_RS00610
uniprot id: R4U0E6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1276227:SCHRY RS03260
gene id: 1276227:SCHRY_RS03260
uniprot id: R4UBF3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family. RnhC subfamily.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1276227:SCHRY RS01800
gene id: 1276227:SCHRY_RS01800
uniprot id: R4UFK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

1276227:SCHRY RS02725
gene id: 1276227:SCHRY_RS02725
uniprot id: R4UB36
names: Subcellular Location Annotation
messages: Membrane

1276227:SCHRY RS01635
gene id: 1276227:SCHRY_RS01635
uniprot id: R4U341
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276227:SCHRY RS03480
gene id: 1276227:SCHRY_RS03480
uniprot id: R4U3Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1276227:SCHRY RS03490
gene id: 1276227:SCHRY_RS03490
uniprot id: R4UGL0
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1276227:SCHRY RS01085
gene id: 1276227:SCHRY_RS01085
uniprot id: R4UA82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1276227:SCHRY RS01620
gene id: 1276227:SCHRY_RS01620
uniprot id: R4UFH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1276227:SCHRY RS03595
gene id: 1276227:SCHRY_RS03595
uniprot id: R4UIZ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

1276227:SCHRY RS03240
gene id: 1276227:SCHRY_RS03240
uniprot id: R4UGH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1276227:SCHRY RS04095
gene id: 1276227:SCHRY_RS04095
uniprot id: R4U490
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276227:SCHRY RS03715
gene id: 1276227:SCHRY_RS03715
uniprot id: R4UJ19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1276227:SCHRY RS00240
gene id: 1276227:SCHRY_RS00240
uniprot id: R4UEW2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1276227:SCHRY RS05035
gene id: 1276227:SCHRY_RS05035
uniprot id: R4UJS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1276227:SCHRY RS04775
gene id: 1276227:SCHRY_RS04775
uniprot id: R4UC84
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1276227:SCHRY RS01485
gene id: 1276227:SCHRY_RS01485
uniprot id: R4U314
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1276227:SCHRY RS04295
gene id: 1276227:SCHRY_RS04295
uniprot id: R4U4B7
names: Similarity
messages: Belongs to the FBPase class 2 family.

1276227:SCHRY RS02680
gene id: 1276227:SCHRY_RS02680
uniprot id: R4UG38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1276227:SCHRY RS03005
gene id: 1276227:SCHRY_RS03005
uniprot id: R4UBB3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276227:SCHRY RS04155
gene id: 1276227:SCHRY_RS04155
uniprot id: R4UJA0
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

1276227:SCHRY RS01600
gene id: 1276227:SCHRY_RS01600
uniprot id: R4UHV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

1276227:SCHRY RS02185
gene id: 1276227:SCHRY_RS02185
uniprot id: R4UI65
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1276227:SCHRY RS00975
gene id: 1276227:SCHRY_RS00975
uniprot id: R4U0J6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1276227:SCHRY RS03545
gene id: 1276227:SCHRY_RS03545
uniprot id: R4UIY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1276227:SCHRY RS02150
gene id: 1276227:SCHRY_RS02150
uniprot id: R4UAR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

1276227:SCHRY RS00460
gene id: 1276227:SCHRY_RS00460
uniprot id: R4U0C8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1276227:SCHRY RS04440
gene id: 1276227:SCHRY_RS04440
uniprot id: R4U4E9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1276227:SCHRY RS00100
gene id: 1276227:SCHRY_RS00100
uniprot id: R4UH01
names: Subcellular Location Annotation
messages: Membrane

1276227:SCHRY RS04110
gene id: 1276227:SCHRY_RS04110
uniprot id: R4UJ89
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1276227:SCHRY RS01330
gene id: 1276227:SCHRY_RS01330
uniprot id: R4U0Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1276227:SCHRY RS01065
gene id: 1276227:SCHRY_RS01065
uniprot id: R4UF87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1276227:SCHRY RS00385
gene id: 1276227:SCHRY_RS00385
uniprot id: R4U2J8
names: Subcellular Location Annotation
messages: Membrane

1276227:SCHRY RS01900
gene id: 1276227:SCHRY_RS01900
uniprot id: R4UAM0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1276227:SCHRY RS00530
gene id: 1276227:SCHRY_RS00530
uniprot id: R4UH88
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1276227:SCHRY RS04980
gene id: 1276227:SCHRY_RS04980
uniprot id: R4UHA1
names: Similarity
messages: Belongs to the IMPACT family.

1276227:SCHRY RS00320
gene id: 1276227:SCHRY_RS00320
uniprot id: R4UH58
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1276227:SCHRY RS01585
gene id: 1276227:SCHRY_RS01585
uniprot id: R4U331
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1276227:SCHRY RS00805
gene id: 1276227:SCHRY_RS00805
uniprot id: R4UF48
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276227:SCHRY RS02605
gene id: 1276227:SCHRY_RS02605
uniprot id: R4UG19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1276227:SCHRY RS01645
gene id: 1276227:SCHRY_RS01645
uniprot id: R4UFH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1276227:SCHRY RS01300
gene id: 1276227:SCHRY_RS01300
uniprot id: R4UHN4
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1276227:SCHRY RS03600
gene id: 1276227:SCHRY_RS03600
uniprot id: R4U1T4
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1276227:SCHRY RS01480
gene id: 1276227:SCHRY_RS01480
uniprot id: R4U0S2
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1276227:SCHRY RS02785
gene id: 1276227:SCHRY_RS02785
uniprot id: R4UIK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1276227:SCHRY RS05175
gene id: 1276227:SCHRY_RS05175
uniprot id: R4UCG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1276227:SCHRY RS04230
gene id: 1276227:SCHRY_RS04230
uniprot id: R4UGW5
names: Subcellular Location Annotation
messages: Membrane

1276227:SCHRY RS02570
gene id: 1276227:SCHRY_RS02570
uniprot id: R4U3K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1276227:SCHRY RS01545
gene id: 1276227:SCHRY_RS01545
uniprot id: R4UFG3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1276227:SCHRY RS01100
gene id: 1276227:SCHRY_RS01100
uniprot id: R4U0L5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1276227:SCHRY RS00125
gene id: 1276227:SCHRY_RS00125
uniprot id: R4UH06
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1276227:SCHRY RS00430
gene id: 1276227:SCHRY_RS00430
uniprot id: R4UH72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Membrane

1276227:SCHRY RS01805
gene id: 1276227:SCHRY_RS01805
uniprot id: R4UHZ5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1276227:SCHRY RS02995
gene id: 1276227:SCHRY_RS02995
uniprot id: R4U1I6
names: Similarity
messages: Belongs to the ribF family.

1276227:SCHRY RS03530
gene id: 1276227:SCHRY_RS03530
uniprot id: R4U403
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1276227:SCHRY RS05195
gene id: 1276227:SCHRY_RS05195
uniprot id: R4U4V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Cell membrane
messages: Membrane

1276227:SCHRY RS00230
gene id: 1276227:SCHRY_RS00230
uniprot id: R4U095
names: Subcellular Location Annotation
messages: Membrane

1276227:SCHRY RS04315
gene id: 1276227:SCHRY_RS04315
uniprot id: R4U245
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

1276227:SCHRY RS02735
gene id: 1276227:SCHRY_RS02735
uniprot id: R4UIH7
names: Similarity
messages: Belongs to the RutC family.

1276227:SCHRY RS00820
gene id: 1276227:SCHRY_RS00820
uniprot id: R4U2P9
names: Similarity
messages: Belongs to the RpoE family.

1276227:SCHRY RS02125
gene id: 1276227:SCHRY_RS02125
uniprot id: R4UAQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1276227:SCHRY RS00105
gene id: 1276227:SCHRY_RS00105
uniprot id: R4U054
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1276227:SCHRY RS04105
gene id: 1276227:SCHRY_RS04105
uniprot id: R4UGV1
names: Subcellular Location Annotation
messages: Membrane

1276227:SCHRY RS03700
gene id: 1276227:SCHRY_RS03700
uniprot id: R4U431
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1276227:SCHRY RS01845
gene id: 1276227:SCHRY_RS01845
uniprot id: R4UAL0
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

1276227:SCHRY RS02980
gene id: 1276227:SCHRY_RS02980
uniprot id: R4UBA8
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1276227:SCHRY RS00960
gene id: 1276227:SCHRY_RS00960
uniprot id: R4UA65
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1276227:SCHRY RS05155
gene id: 1276227:SCHRY_RS05155
uniprot id: R4UHE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1276227:SCHRY RS04885
gene id: 1276227:SCHRY_RS04885
uniprot id: R4UJP6
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1276227:SCHRY RS03845
gene id: 1276227:SCHRY_RS03845
uniprot id: R4UGR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1276227:SCHRY RS03195
gene id: 1276227:SCHRY_RS03195
uniprot id: R4UIS4
names: Subcellular Location Annotation
messages: Membrane

1276227:SCHRY RS04590
gene id: 1276227:SCHRY_RS04590
uniprot id: R4UC33
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

1276227:SCHRY RS01260
gene id: 1276227:SCHRY_RS01260
uniprot id: R4U2W9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

1276227:SCHRY RS00770
gene id: 1276227:SCHRY_RS00770
uniprot id: R4U2P4
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1276227:SCHRY RS00875
gene id: 1276227:SCHRY_RS00875
uniprot id: R4UA54
names: Similarity
messages: Belongs to the carbamate kinase family.

1276227:SCHRY RS01090
gene id: 1276227:SCHRY_RS01090
uniprot id: R4UF92
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

1276227:SCHRY RS00490
gene id: 1276227:SCHRY_RS00490
uniprot id: R4U2L1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1276227:SCHRY RS02320
gene id: 1276227:SCHRY_RS02320
uniprot id: R4UAV2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1276227:SCHRY RS00730
gene id: 1276227:SCHRY_RS00730
uniprot id: R4UF36
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1276227:SCHRY RS03305
gene id: 1276227:SCHRY_RS03305
uniprot id: R4U3X8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1276227:SCHRY RS01520
gene id: 1276227:SCHRY_RS01520
uniprot id: R4UFF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1276227:SCHRY RS01630
gene id: 1276227:SCHRY_RS01630
uniprot id: R4U0U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1276227:SCHRY RS00865
gene id: 1276227:SCHRY_RS00865
uniprot id: R4U0I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1276227:SCHRY RS03755
gene id: 1276227:SCHRY_RS03755
uniprot id: R4UBN2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1276227:SCHRY RS02845
gene id: 1276227:SCHRY_RS02845
uniprot id: R4U3S3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1276227:SCHRY RS05440
gene id: 1276227:SCHRY_RS05440
uniprot id: R4U2X4
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1276227:SCHRY RS02195
gene id: 1276227:SCHRY_RS02195
uniprot id: R4U3D2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1276227:SCHRY RS00870
gene id: 1276227:SCHRY_RS00870
uniprot id: R4U2Q5
names: Subcellular Location Annotation
messages: Membrane

1276227:SCHRY RS01210
gene id: 1276227:SCHRY_RS01210
uniprot id: R4U2V9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1276227:SCHRY RS03945
gene id: 1276227:SCHRY_RS03945
uniprot id: R4UBQ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1276227:SCHRY RS04470
gene id: 1276227:SCHRY_RS04470
uniprot id: R4UJF9
names: Similarity
messages: Belongs to the Fur family.

1276227:SCHRY RS03395
gene id: 1276227:SCHRY_RS03395
uniprot id: R4UIW1
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

1276227:SCHRY RS01265
gene id: 1276227:SCHRY_RS01265
uniprot id: R4UAA3
names: Function
names: Similarity
messages: Belongs to the OMP decarboxylase family.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).

1276227:SCHRY RS02420
gene id: 1276227:SCHRY_RS02420
uniprot id: R4UAX3
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

1276227:SCHRY RS00635
gene id: 1276227:SCHRY_RS00635
uniprot id: R4U0F1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1276227:SCHRY RS05130
gene id: 1276227:SCHRY_RS05130
uniprot id: R4UHD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1276227:SCHRY RS00720
gene id: 1276227:SCHRY_RS00720
uniprot id: R4U2N7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1276227:SCHRY RS03075
gene id: 1276227:SCHRY_RS03075
uniprot id: R4U1J8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1276227:SCHRY RS05030
gene id: 1276227:SCHRY_RS05030
uniprot id: R4UHB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1276227:SCHRY RS01595
gene id: 1276227:SCHRY_RS01595
uniprot id: R4UFH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1276227:SCHRY RS00435
gene id: 1276227:SCHRY_RS00435
uniprot id: R4U0C3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1276227:SCHRY RS00265
gene id: 1276227:SCHRY_RS00265
uniprot id: R4UEW7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1276227:SCHRY RS01010
gene id: 1276227:SCHRY_RS01010
uniprot id: R4UA72
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1276227:SCHRY RS03055
gene id: 1276227:SCHRY_RS03055
uniprot id: R4U3U9
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1276227:SCHRY RS00285
gene id: 1276227:SCHRY_RS00285
uniprot id: R4U9X4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1276227:SCHRY RS02020
gene id: 1276227:SCHRY_RS02020
uniprot id: R4UI33
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1276227:SCHRY RS00495
gene id: 1276227:SCHRY_RS00495
uniprot id: R4UA01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1276227:SCHRY RS04975
gene id: 1276227:SCHRY_RS04975
uniprot id: R4UCC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1276227:SCHRY RS00315
gene id: 1276227:SCHRY_RS00315
uniprot id: R4UEX6
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1276227:SCHRY RS00445
gene id: 1276227:SCHRY_RS00445
uniprot id: R4U9Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1276227:SCHRY RS00735
gene id: 1276227:SCHRY_RS00735
uniprot id: R4UHC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1276227:SCHRY RS01920
gene id: 1276227:SCHRY_RS01920
uniprot id: R4U389
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276227:SCHRY RS03060
gene id: 1276227:SCHRY_RS03060
uniprot id: R4UBC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

1276227:SCHRY RS02275
gene id: 1276227:SCHRY_RS02275
uniprot id: R4UAU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0154 family.
messages: Membrane

1276227:SCHRY RS01070
gene id: 1276227:SCHRY_RS01070
uniprot id: R4UHJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1276227:SCHRY RS00345
gene id: 1276227:SCHRY_RS00345
uniprot id: R4UH62
names: Similarity
messages: Belongs to the IMPACT family.

1276227:SCHRY RS00695
gene id: 1276227:SCHRY_RS00695
uniprot id: R4U2N5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1276227:SCHRY RS00800
gene id: 1276227:SCHRY_RS00800
uniprot id: R4UA43
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1276227:SCHRY RS02855
gene id: 1276227:SCHRY_RS02855
uniprot id: R4UGB1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1276227:SCHRY RS04520
gene id: 1276227:SCHRY_RS04520
uniprot id: R4UH08
names: Subcellular Location Annotation
messages: Membrane

1276227:SCHRY RS01125
gene id: 1276227:SCHRY_RS01125
uniprot id: R4U0L9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1276227:SCHRY RS05085
gene id: 1276227:SCHRY_RS05085
uniprot id: R4UJT4
names: Subcellular Location Annotation
messages: Membrane

1276227:SCHRY RS01140
gene id: 1276227:SCHRY_RS01140
uniprot id: R4UFA0
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1276227:SCHRY RS04395
gene id: 1276227:SCHRY_RS04395
uniprot id: R4U256
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.

1276227:SCHRY RS00625
gene id: 1276227:SCHRY_RS00625
uniprot id: R4UF21
names: Similarity
messages: Belongs to the Lgt family.

1276227:SCHRY RS01255
gene id: 1276227:SCHRY_RS01255
uniprot id: R4U0N7
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

1276227:SCHRY RS03550
gene id: 1276227:SCHRY_RS03550
uniprot id: R4U1S6
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276227:SCHRY RS00740
gene id: 1276227:SCHRY_RS00740
uniprot id: R4U0G4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1276227:SCHRY RS02490
gene id: 1276227:SCHRY_RS02490
uniprot id: R4U162
names: Similarity
messages: Belongs to the DNA photolyase family.

1276227:SCHRY RS01175
gene id: 1276227:SCHRY_RS01175
uniprot id: R4U0M6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1276227:SCHRY RS05205
gene id: 1276227:SCHRY_RS05205
uniprot id: R4UHF8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1276227:SCHRY RS03025
gene id: 1276227:SCHRY_RS03025
uniprot id: R4U3U7
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1276227:SCHRY RS03525
gene id: 1276227:SCHRY_RS03525
uniprot id: R4U1S3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1276227:SCHRY RS01150
gene id: 1276227:SCHRY_RS01150
uniprot id: R4U0M3
names: Subcellular Location Annotation
messages: Cytoplasm

1276227:SCHRY RS04345
gene id: 1276227:SCHRY_RS04345
uniprot id: R4U4C8
names: Function
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

1276227:SCHRY RS04080
gene id: 1276227:SCHRY_RS04080
uniprot id: R4UGU7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1276227:SCHRY RS00890
gene id: 1276227:SCHRY_RS00890
uniprot id: R4U0I7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1276227:SCHRY RS02990
gene id: 1276227:SCHRY_RS02990
uniprot id: R4UIN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1276227:SCHRY RS03065
gene id: 1276227:SCHRY_RS03065
uniprot id: R4UGE3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1276227:SCHRY RS03220
gene id: 1276227:SCHRY_RS03220
uniprot id: R4UIS8
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276227:SCHRY RS00180
gene id: 1276227:SCHRY_RS00180
uniprot id: R4U067
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1276227:SCHRY RS00845
gene id: 1276227:SCHRY_RS00845
uniprot id: R4U2Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1276227:SCHRY RS04570
gene id: 1276227:SCHRY_RS04570
uniprot id: R4UH18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1276227:SCHRY RS01515
gene id: 1276227:SCHRY_RS01515
uniprot id: R4UAE1
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

1276227:SCHRY RS00170
gene id: 1276227:SCHRY_RS00170
uniprot id: R4UER1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1276227:SCHRY RS00630
gene id: 1276227:SCHRY_RS00630
uniprot id: R4UHA6
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

1276227:SCHRY RS04255
gene id: 1276227:SCHRY_RS04255
uniprot id: R4UGW8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1276227:SCHRY RS04550
gene id: 1276227:SCHRY_RS04550
uniprot id: R4UJH4
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1276227:SCHRY RS00510
gene id: 1276227:SCHRY_RS00510
uniprot id: R4U0D4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1276227:SCHRY RS01025
gene id: 1276227:SCHRY_RS01025
uniprot id: R4U0K6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1276227:SCHRY RS01490
gene id: 1276227:SCHRY_RS01490
uniprot id: R4UAD8
names: Subcellular Location Annotation
messages: Membrane

1276227:SCHRY RS02370
gene id: 1276227:SCHRY_RS02370
uniprot id: R4UAW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1276227:SCHRY RS03675
gene id: 1276227:SCHRY_RS03675
uniprot id: R4U425
names: Subcellular Location Annotation
messages: Cytoplasm

1276227:SCHRY RS00135
gene id: 1276227:SCHRY_RS00135
uniprot id: R4U2D9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1276227:SCHRY RS04030
gene id: 1276227:SCHRY_RS04030
uniprot id: R4UGT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1276227:SCHRY RS05070
gene id: 1276227:SCHRY_RS05070
uniprot id: R4U4T0
names: Subcellular Location Annotation
messages: Membrane

1276227:SCHRY RS04830
gene id: 1276227:SCHRY_RS04830
uniprot id: R4UC94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1276227:SCHRY RS00010
gene id: 1276227:SCHRY_RS00010
uniprot id: R4U9P7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1276227:SCHRY RS03245
gene id: 1276227:SCHRY_RS03245
uniprot id: R4UIT3
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1276227:SCHRY RS02685
gene id: 1276227:SCHRY_RS02685
uniprot id: R4UIG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1276227:SCHRY RS01115
gene id: 1276227:SCHRY_RS01115
uniprot id: R4UF97
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1276227:SCHRY RS01410
gene id: 1276227:SCHRY_RS01410
uniprot id: R4U2Z8
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1276227:SCHRY RS03265
gene id: 1276227:SCHRY_RS03265
uniprot id: R4UGH3
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1276227:SCHRY RS04495
gene id: 1276227:SCHRY_RS04495
uniprot id: R4UJG4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1276227:SCHRY RS03610
gene id: 1276227:SCHRY_RS03610
uniprot id: R4UBK9
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

1276227:SCHRY RS05190
gene id: 1276227:SCHRY_RS05190
uniprot id: R4U2J3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276227:SCHRY RS00365
gene id: 1276227:SCHRY_RS00365
uniprot id: R4U9Y4
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1276227:SCHRY RS00185
gene id: 1276227:SCHRY_RS00185
uniprot id: R4U2E7
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1276227:SCHRY RS00045
gene id: 1276227:SCHRY_RS00045
uniprot id: R4UEN2
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1276227:SCHRY RS03215
gene id: 1276227:SCHRY_RS03215
uniprot id: R4UGG6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1276227:SCHRY RS01655
gene id: 1276227:SCHRY_RS01655
uniprot id: R4U0U6
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1276227:SCHRY RS00905
gene id: 1276227:SCHRY_RS00905
uniprot id: R4UF64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1276227:SCHRY RS04320
gene id: 1276227:SCHRY_RS04320
uniprot id: R4U4C2
names: Similarity
messages: Belongs to the peptidase M17 family.

1276227:SCHRY RS02070
gene id: 1276227:SCHRY_RS02070
uniprot id: R4U3A8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276227:SCHRY RS03940
gene id: 1276227:SCHRY_RS03940
uniprot id: R4U465
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1276227:SCHRY RS03635
gene id: 1276227:SCHRY_RS03635
uniprot id: R4UGN4
names: Similarity
messages: Belongs to the lipase/esterase LIP3/BchO family.

1276227:SCHRY RS03790
gene id: 1276227:SCHRY_RS03790
uniprot id: R4UBN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1276227:SCHRY RS00840
gene id: 1276227:SCHRY_RS00840
uniprot id: R4U0H9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1276227:SCHRY RS04825
gene id: 1276227:SCHRY_RS04825
uniprot id: R4U4M6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1276227:SCHRY RS00900
gene id: 1276227:SCHRY_RS00900
uniprot id: R4UA58
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276227:SCHRY RS02760
gene id: 1276227:SCHRY_RS02760
uniprot id: R4UII2
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1276227:SCHRY RS04235
gene id: 1276227:SCHRY_RS04235
uniprot id: R4UJB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1276227:SCHRY RS04535
gene id: 1276227:SCHRY_RS04535
uniprot id: R4U4G3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1276227:SCHRY RS04115
gene id: 1276227:SCHRY_RS04115
uniprot id: R4U214
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1276227:SCHRY RS00410
gene id: 1276227:SCHRY_RS00410
uniprot id: R4U2K2
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

1276227:SCHRY RS03745
gene id: 1276227:SCHRY_RS03745
uniprot id: R4U1V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1276227:SCHRY RS03820
gene id: 1276227:SCHRY_RS03820
uniprot id: R4UGR5
names: Similarity
messages: Belongs to the CutC family.

1276227:SCHRY RS02770
gene id: 1276227:SCHRY_RS02770
uniprot id: R4U3N9
names: Subcellular Location Annotation
messages: Membrane

1276227:SCHRY RS04340
gene id: 1276227:SCHRY_RS04340
uniprot id: R4U250
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

1276227:SCHRY RS03280
gene id: 1276227:SCHRY_RS03280
uniprot id: R4U3X5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1276227:SCHRY RS00785
gene id: 1276227:SCHRY_RS00785
uniprot id: R4UHD5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1276227:SCHRY RS01250
gene id: 1276227:SCHRY_RS01250
uniprot id: R4UHM3
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1276227:SCHRY RS02840
gene id: 1276227:SCHRY_RS02840
uniprot id: R4U1F9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1276227:SCHRY RS01680
gene id: 1276227:SCHRY_RS01680
uniprot id: R4U0V1
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1276227:SCHRY RS02495
gene id: 1276227:SCHRY_RS02495
uniprot id: R4U3I9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1276227:SCHRY RS00450
gene id: 1276227:SCHRY_RS00450
uniprot id: R4UEZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1276227:SCHRY RS01080
gene id: 1276227:SCHRY_RS01080
uniprot id: R4U2T5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1276227:SCHRY RS01055
gene id: 1276227:SCHRY_RS01055
uniprot id: R4U2T0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.