1265868:SRIM RS28415
gene id: 1265868:SRIM_RS28415
uniprot id: L8ETV6
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1265868:SRIM RS38640
gene id: 1265868:SRIM_RS38640
uniprot id: L8ETP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS10690
gene id: 1265868:SRIM_RS10690
uniprot id: L8EER4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

1265868:SRIM RS27085
gene id: 1265868:SRIM_RS27085
uniprot id: L8EI36
names: Similarity
messages: Belongs to the LOG family.

1265868:SRIM RS39780
gene id: 1265868:SRIM_RS39780
uniprot id: L8EGQ2
names: Similarity
messages: Belongs to the UPF0225 family.

1265868:SRIM RS25190
gene id: 1265868:SRIM_RS25190
uniprot id: A0A8A1UY09
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1265868:SRIM RS33400
gene id: 1265868:SRIM_RS33400
uniprot id: L8ESQ1
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1265868:SRIM RS10315
gene id: 1265868:SRIM_RS10315
uniprot id: L8EKX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Involved in both the histidine and tryptophan biosynthetic pathways.

1265868:SRIM RS11300
gene id: 1265868:SRIM_RS11300
uniprot id: L8EQ85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1265868:SRIM RS20485
gene id: 1265868:SRIM_RS20485
uniprot id: L8EXT1
names: Subunit
messages: Homodimer.

1265868:SRIM RS21625
gene id: 1265868:SRIM_RS21625
uniprot id: L8F1U4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

1265868:SRIM RS22005
gene id: 1265868:SRIM_RS22005
uniprot id: L8EF91
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS32575
gene id: 1265868:SRIM_RS32575
uniprot id: A0A8A1V0I1
names: Caution
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS18615
gene id: 1265868:SRIM_RS18615
uniprot id: L8EXM7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1265868:SRIM RS38885
gene id: 1265868:SRIM_RS38885
uniprot id: A0A8A1V1X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1265868:SRIM RS03780
gene id: 1265868:SRIM_RS03780
uniprot id: L8EKR7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS16270
gene id: 1265868:SRIM_RS16270
uniprot id: L8EDF4
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS09025
gene id: 1265868:SRIM_RS09025
uniprot id: L8EFX1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1265868:SRIM RS18645
gene id: 1265868:SRIM_RS18645
uniprot id: L8ETJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1265868:SRIM RS38915
gene id: 1265868:SRIM_RS38915
uniprot id: L8ERD6
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

1265868:SRIM RS06635
gene id: 1265868:SRIM_RS06635
uniprot id: L8EPQ4
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

1265868:SRIM RS38405
gene id: 1265868:SRIM_RS38405
uniprot id: L8EUP4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1265868:SRIM RS19285
gene id: 1265868:SRIM_RS19285
uniprot id: L8EFG4
names: Similarity
messages: Belongs to the UbiD family.

1265868:SRIM RS09705
gene id: 1265868:SRIM_RS09705
uniprot id: A0A8A1UNH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1265868:SRIM RS08920
gene id: 1265868:SRIM_RS08920
uniprot id: L8EN57
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

1265868:SRIM RS19130
gene id: 1265868:SRIM_RS19130
uniprot id: L8EKA3
names: Similarity
messages: Belongs to the peptidase C40 family.

1265868:SRIM RS15960
gene id: 1265868:SRIM_RS15960
uniprot id: L8EFX3
names: Similarity
messages: Belongs to the PGI/PMI family.

1265868:SRIM RS10630
gene id: 1265868:SRIM_RS10630
uniprot id: L8EMY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1265868:SRIM RS36285
gene id: 1265868:SRIM_RS36285
uniprot id: L8ETV4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1265868:SRIM RS26050
gene id: 1265868:SRIM_RS26050
uniprot id: A0A8A1URF3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS26725
gene id: 1265868:SRIM_RS26725
uniprot id: L8EEB2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1265868:SRIM RS09890
gene id: 1265868:SRIM_RS09890
uniprot id: L8EL93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1265868:SRIM RS10455
gene id: 1265868:SRIM_RS10455
uniprot id: A0A8A1UKK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

1265868:SRIM RS34870
gene id: 1265868:SRIM_RS34870
uniprot id: L8EH02
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1265868:SRIM RS24740
gene id: 1265868:SRIM_RS24740
uniprot id: L8EE00
names: Subcellular Location Annotation
messages: Cytoplasm

1265868:SRIM RS19090
gene id: 1265868:SRIM_RS19090
uniprot id: L8ERV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1265868:SRIM RS10950
gene id: 1265868:SRIM_RS10950
uniprot id: L8ERV6
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1265868:SRIM RS25035
gene id: 1265868:SRIM_RS25035
uniprot id: L8ES30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS24000
gene id: 1265868:SRIM_RS24000
uniprot id: L8EEP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS06715
gene id: 1265868:SRIM_RS06715
uniprot id: L8EQQ6
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1265868:SRIM RS07565
gene id: 1265868:SRIM_RS07565
uniprot id: A0A8A1UKH0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1265868:SRIM RS25195
gene id: 1265868:SRIM_RS25195
uniprot id: A0A8A1UQ38
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1265868:SRIM RS35710
gene id: 1265868:SRIM_RS35710
uniprot id: L8ERN4
names: Similarity
messages: Belongs to the universal stress protein A family.

1265868:SRIM RS15325
gene id: 1265868:SRIM_RS15325
uniprot id: L8EJX6
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS25260
gene id: 1265868:SRIM_RS25260
uniprot id: L8ENS8
names: Similarity
messages: Belongs to the HIBADH-related family.

1265868:SRIM RS25600
gene id: 1265868:SRIM_RS25600
uniprot id: A0A8A1UQB4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1265868:SRIM RS37400
gene id: 1265868:SRIM_RS37400
uniprot id: L8EFU9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1265868:SRIM RS11365
gene id: 1265868:SRIM_RS11365
uniprot id: L8EPD8
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS18625
gene id: 1265868:SRIM_RS18625
uniprot id: L8EUC7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1265868:SRIM RS35895
gene id: 1265868:SRIM_RS35895
uniprot id: L8ERG6
names: Similarity
messages: Belongs to the terpene synthase family.

1265868:SRIM RS29885
gene id: 1265868:SRIM_RS29885
uniprot id: L8EYA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1265868:SRIM RS04150
gene id: 1265868:SRIM_RS04150
uniprot id: L8ELF5
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS18775
gene id: 1265868:SRIM_RS18775
uniprot id: L8EU91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1265868:SRIM RS09295
gene id: 1265868:SRIM_RS09295
uniprot id: L8EFE2
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and hydrogenobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of hydrogenobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CobB catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

1265868:SRIM RS29855
gene id: 1265868:SRIM_RS29855
uniprot id: L8EYA7
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1265868:SRIM RS07270
gene id: 1265868:SRIM_RS07270
uniprot id: L8EQ52
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1265868:SRIM RS09095
gene id: 1265868:SRIM_RS09095
uniprot id: L8EH45
names: Similarity
messages: Belongs to the peptidase U62 family.

1265868:SRIM RS13785
gene id: 1265868:SRIM_RS13785
uniprot id: A0A8A1UK22
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1265868:SRIM RS09080
gene id: 1265868:SRIM_RS09080
uniprot id: L8EKJ0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1265868:SRIM RS26740
gene id: 1265868:SRIM_RS26740
uniprot id: A0A8A1UTT1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1265868:SRIM RS09500
gene id: 1265868:SRIM_RS09500
uniprot id: L8EM93
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1265868:SRIM RS03255
gene id: 1265868:SRIM_RS03255
uniprot id: L8EM71
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1265868:SRIM RS19010
gene id: 1265868:SRIM_RS19010
uniprot id: L8EMS6
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS06720
gene id: 1265868:SRIM_RS06720
uniprot id: L8EQJ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1265868:SRIM RS25245
gene id: 1265868:SRIM_RS25245
uniprot id: A0A8A1UR03
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1265868:SRIM RS18350
gene id: 1265868:SRIM_RS18350
uniprot id: L8EJM6
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1265868:SRIM RS03435
gene id: 1265868:SRIM_RS03435
uniprot id: A0A8A1UHF6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1265868:SRIM RS32280
gene id: 1265868:SRIM_RS32280
uniprot id: L8EJX3
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS13835
gene id: 1265868:SRIM_RS13835
uniprot id: L8EJD8
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1265868:SRIM RS04115
gene id: 1265868:SRIM_RS04115
uniprot id: L8EPZ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

1265868:SRIM RS32750
gene id: 1265868:SRIM_RS32750
uniprot id: L8EP20
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1265868:SRIM RS33660
gene id: 1265868:SRIM_RS33660
uniprot id: L8ETA7
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

1265868:SRIM RS34940
gene id: 1265868:SRIM_RS34940
uniprot id: A0A8A1V2C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

1265868:SRIM RS29880
gene id: 1265868:SRIM_RS29880
uniprot id: L8EXS4
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1265868:SRIM RS33255
gene id: 1265868:SRIM_RS33255
uniprot id: A0A8A1V0N7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1265868:SRIM RS35960
gene id: 1265868:SRIM_RS35960
uniprot id: L8ERA1
names: Similarity
messages: Belongs to the peptidase C40 family.

1265868:SRIM RS01890
gene id: 1265868:SRIM_RS01890
uniprot id: L8ERN1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1265868:SRIM RS29440
gene id: 1265868:SRIM_RS29440
uniprot id: L8ENE5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1265868:SRIM RS14185
gene id: 1265868:SRIM_RS14185
uniprot id: L8ERH0
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

1265868:SRIM RS30040
gene id: 1265868:SRIM_RS30040
uniprot id: L8F0U2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1265868:SRIM RS15055
gene id: 1265868:SRIM_RS15055
uniprot id: L8EJR0
names: Similarity
messages: Belongs to the peptidase C40 family.

1265868:SRIM RS17190
gene id: 1265868:SRIM_RS17190
uniprot id: L8EYH2
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS08555
gene id: 1265868:SRIM_RS08555
uniprot id: L8EJL6
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

1265868:SRIM RS30980
gene id: 1265868:SRIM_RS30980
uniprot id: L8EQZ9
names: Subcellular Location Annotation
messages: Cell membrane

1265868:SRIM RS18690
gene id: 1265868:SRIM_RS18690
uniprot id: L8EXL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1265868:SRIM RS07730
gene id: 1265868:SRIM_RS07730
uniprot id: L8ESX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

1265868:SRIM RS34020
gene id: 1265868:SRIM_RS34020
uniprot id: L8ELX3
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1265868:SRIM RS06910
gene id: 1265868:SRIM_RS06910
uniprot id: L8EK33
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1265868:SRIM RS13485
gene id: 1265868:SRIM_RS13485
uniprot id: L8EVL4
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1265868:SRIM RS38850
gene id: 1265868:SRIM_RS38850
uniprot id: L8ETE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Fes family.
messages: Cytoplasm

1265868:SRIM RS28205
gene id: 1265868:SRIM_RS28205
uniprot id: L8ETZ9
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS03530
gene id: 1265868:SRIM_RS03530
uniprot id: L8ENE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

1265868:SRIM RS18910
gene id: 1265868:SRIM_RS18910
uniprot id: L8EF80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1265868:SRIM RS23345
gene id: 1265868:SRIM_RS23345
uniprot id: A0A8A1US24
names: Similarity
messages: Belongs to the thioesterase family.

1265868:SRIM RS36460
gene id: 1265868:SRIM_RS36460
uniprot id: L8EV46
names: Similarity
messages: Belongs to the UPF0047 family.

1265868:SRIM RS29135
gene id: 1265868:SRIM_RS29135
uniprot id: L8EID3
names: Similarity
messages: Belongs to the LOG family.

1265868:SRIM RS35640
gene id: 1265868:SRIM_RS35640
uniprot id: L8EQC5
names: Similarity
messages: Belongs to the cytochrome P450 family.

1265868:SRIM RS14830
gene id: 1265868:SRIM_RS14830
uniprot id: L8EP66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1265868:SRIM RS01065
gene id: 1265868:SRIM_RS01065
uniprot id: L8EXR6
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1265868:SRIM RS07765
gene id: 1265868:SRIM_RS07765
uniprot id: L8EU34
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1265868:SRIM RS20205
gene id: 1265868:SRIM_RS20205
uniprot id: L8EXL7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1265868:SRIM RS10330
gene id: 1265868:SRIM_RS10330
uniprot id: L8EK00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1265868:SRIM RS01035
gene id: 1265868:SRIM_RS01035
uniprot id: L8ETP0
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS38260
gene id: 1265868:SRIM_RS38260
uniprot id: A0A8A1UYH1
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

1265868:SRIM RS40365
gene id: 1265868:SRIM_RS40365
uniprot id: L8F190
names: Similarity
messages: Belongs to the UPF0098 family.

1265868:SRIM RS18405
gene id: 1265868:SRIM_RS18405
uniprot id: L8ENZ9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1265868:SRIM RS39845
gene id: 1265868:SRIM_RS39845
uniprot id: L8EWM9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1265868:SRIM RS16640
gene id: 1265868:SRIM_RS16640
uniprot id: L8EKZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

1265868:SRIM RS15340
gene id: 1265868:SRIM_RS15340
uniprot id: L8EGJ8
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1265868:SRIM RS29840
gene id: 1265868:SRIM_RS29840
uniprot id: A0A8A1V5T1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1265868:SRIM RS02350
gene id: 1265868:SRIM_RS02350
uniprot id: L8EYU5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1265868:SRIM RS14925
gene id: 1265868:SRIM_RS14925
uniprot id: L8EIW1
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS23255
gene id: 1265868:SRIM_RS23255
uniprot id: L8ERH4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

1265868:SRIM RS38395
gene id: 1265868:SRIM_RS38395
uniprot id: L8EVF2
names: Similarity
messages: Belongs to the asparagine synthetase family.

1265868:SRIM RS10435
gene id: 1265868:SRIM_RS10435
uniprot id: L8EGZ8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1265868:SRIM RS04960
gene id: 1265868:SRIM_RS04960
uniprot id: L8EQR9
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1265868:SRIM RS27465
gene id: 1265868:SRIM_RS27465
uniprot id: A0A8A1UXW1
names: Similarity
messages: Belongs to the catalase family.

1265868:SRIM RS02020
gene id: 1265868:SRIM_RS02020
uniprot id: L8EN88
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

1265868:SRIM RS19635
gene id: 1265868:SRIM_RS19635
uniprot id: L8EUS3
names: Similarity
messages: Belongs to the histone deacetylase family.

1265868:SRIM RS18390
gene id: 1265868:SRIM_RS18390
uniprot id: L8EL05
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1265868:SRIM RS18540
gene id: 1265868:SRIM_RS18540
uniprot id: L8EXP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

1265868:SRIM RS16010
gene id: 1265868:SRIM_RS16010
uniprot id: L8EMN4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofD family.
messages: Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS11335
gene id: 1265868:SRIM_RS11335
uniprot id: L8ETH2
names: Similarity
messages: Belongs to the glutamine synthetase family.

1265868:SRIM RS30450
gene id: 1265868:SRIM_RS30450
uniprot id: L8EM37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1265868:SRIM RS15110
gene id: 1265868:SRIM_RS15110
uniprot id: L8EJQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1265868:SRIM RS30010
gene id: 1265868:SRIM_RS30010
uniprot id: L8EX01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1265868:SRIM RS17040
gene id: 1265868:SRIM_RS17040
uniprot id: A0A8A1UU93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1265868:SRIM RS26995
gene id: 1265868:SRIM_RS26995
uniprot id: L8ES56
names: Similarity
messages: Belongs to the peptidase S9C family.

1265868:SRIM RS28565
gene id: 1265868:SRIM_RS28565
uniprot id: L8EPS5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1265868:SRIM RS00650
gene id: 1265868:SRIM_RS00650
uniprot id: L8EZP0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1265868:SRIM RS10655
gene id: 1265868:SRIM_RS10655
uniprot id: L8EMX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Homooligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1265868:SRIM RS15675
gene id: 1265868:SRIM_RS15675
uniprot id: A0A8A1ULJ3
names: Similarity
messages: Belongs to the peptidase S41A family.

1265868:SRIM RS10510
gene id: 1265868:SRIM_RS10510
uniprot id: L8EEN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1265868:SRIM RS11430
gene id: 1265868:SRIM_RS11430
uniprot id: L8EI54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS04860
gene id: 1265868:SRIM_RS04860
uniprot id: L8EQV4
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

1265868:SRIM RS11015
gene id: 1265868:SRIM_RS11015
uniprot id: L8EEF2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1265868:SRIM RS38370
gene id: 1265868:SRIM_RS38370
uniprot id: A0A8A1V135
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1265868:SRIM RS21465
gene id: 1265868:SRIM_RS21465
uniprot id: L8F4B8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An FAD-requiring monooxygenase active on some tetracycline antibiotic derivatives, which leads to their inactivation. Hydroxylates carbon 11a of tetracycline and some analogs.
messages: Belongs to the aromatic-ring hydroxylase family. TetX subfamily.
messages: Consists of an N-terminal FAD-binding domain with a Rossman fold and a C-terminal substrate-binding domain.
messages: Cytoplasm
messages: Monomer.

1265868:SRIM RS13500
gene id: 1265868:SRIM_RS13500
uniprot id: A0A8A1UNH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

1265868:SRIM RS27710
gene id: 1265868:SRIM_RS27710
uniprot id: A0A8A1UR88
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

1265868:SRIM RS33800
gene id: 1265868:SRIM_RS33800
uniprot id: L8EWI7
names: Similarity
messages: Belongs to the bleomycin resistance protein family.

1265868:SRIM RS31405
gene id: 1265868:SRIM_RS31405
uniprot id: L8EHH6
names: Similarity
messages: Belongs to the peptidase M20A family.

1265868:SRIM RS19095
gene id: 1265868:SRIM_RS19095
uniprot id: A0A8A1UPZ7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1265868:SRIM RS18430
gene id: 1265868:SRIM_RS18430
uniprot id: L8EP02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1265868:SRIM RS18770
gene id: 1265868:SRIM_RS18770
uniprot id: L8ETG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1265868:SRIM RS36275
gene id: 1265868:SRIM_RS36275
uniprot id: L8EWS4
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS17905
gene id: 1265868:SRIM_RS17905
uniprot id: L8EZ02
names: Similarity
messages: Belongs to the peptidase S11 family.

1265868:SRIM RS32050
gene id: 1265868:SRIM_RS32050
uniprot id: L8EV79
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1265868:SRIM RS33330
gene id: 1265868:SRIM_RS33330
uniprot id: L8EQU6
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1265868:SRIM RS28845
gene id: 1265868:SRIM_RS28845
uniprot id: A0A8A1UW81
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

1265868:SRIM RS19960
gene id: 1265868:SRIM_RS19960
uniprot id: L8EZU4
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS30015
gene id: 1265868:SRIM_RS30015
uniprot id: L8F0U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1265868:SRIM RS15685
gene id: 1265868:SRIM_RS15685
uniprot id: L8EEL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1265868:SRIM RS20555
gene id: 1265868:SRIM_RS20555
uniprot id: L8F1P1
names: Similarity
messages: Belongs to the alkaline phosphatase family.

1265868:SRIM RS38460
gene id: 1265868:SRIM_RS38460
uniprot id: L8EYQ2
names: Function
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.

1265868:SRIM RS06690
gene id: 1265868:SRIM_RS06690
uniprot id: L8EQQ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1265868:SRIM RS29995
gene id: 1265868:SRIM_RS29995
uniprot id: L8EWX0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1265868:SRIM RS23630
gene id: 1265868:SRIM_RS23630
uniprot id: L8ER40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1265868:SRIM RS32070
gene id: 1265868:SRIM_RS32070
uniprot id: L8EUJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1265868:SRIM RS02370
gene id: 1265868:SRIM_RS02370
uniprot id: A0A8A1UHR7
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

1265868:SRIM RS04345
gene id: 1265868:SRIM_RS04345
uniprot id: L8EM08
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1265868:SRIM RS37220
gene id: 1265868:SRIM_RS37220
uniprot id: L8EW64
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

1265868:SRIM RS25120
gene id: 1265868:SRIM_RS25120
uniprot id: L8ES64
names: Similarity
messages: Belongs to the UPF0309 family.

1265868:SRIM RS33225
gene id: 1265868:SRIM_RS33225
uniprot id: L8EQQ4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1265868:SRIM RS16070
gene id: 1265868:SRIM_RS16070
uniprot id: L8EQY7
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1265868:SRIM RS12285
gene id: 1265868:SRIM_RS12285
uniprot id: L8EP01
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS28350
gene id: 1265868:SRIM_RS28350
uniprot id: L8EV34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1265868:SRIM RS00745
gene id: 1265868:SRIM_RS00745
uniprot id: L8EZM4
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS42155
gene id: 1265868:SRIM_RS42155
uniprot id: L8F1H8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS18530
gene id: 1265868:SRIM_RS18530
uniprot id: L8EUU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1265868:SRIM RS05865
gene id: 1265868:SRIM_RS05865
uniprot id: L8EGF6
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS03870
gene id: 1265868:SRIM_RS03870
uniprot id: L8EMT0
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1265868:SRIM RS00325
gene id: 1265868:SRIM_RS00325
uniprot id: L8F0N0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1265868:SRIM RS34335
gene id: 1265868:SRIM_RS34335
uniprot id: L8EV31
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

1265868:SRIM RS11580
gene id: 1265868:SRIM_RS11580
uniprot id: L8EU37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS11100
gene id: 1265868:SRIM_RS11100
uniprot id: L8ENQ0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

1265868:SRIM RS06810
gene id: 1265868:SRIM_RS06810
uniprot id: L8EK17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1265868:SRIM RS32580
gene id: 1265868:SRIM_RS32580
uniprot id: L8EMV3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1265868:SRIM RS28190
gene id: 1265868:SRIM_RS28190
uniprot id: L8EV53
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1265868:SRIM RS33830
gene id: 1265868:SRIM_RS33830
uniprot id: L8ESC7
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1265868:SRIM RS30580
gene id: 1265868:SRIM_RS30580
uniprot id: L8EF40
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1265868:SRIM RS23885
gene id: 1265868:SRIM_RS23885
uniprot id: L8EPP4
names: Similarity
messages: Belongs to the Nth/MutY family.

1265868:SRIM RS26375
gene id: 1265868:SRIM_RS26375
uniprot id: L8ES08
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.
messages: Belongs to the MshB deacetylase family. Mca subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Monomer.

1265868:SRIM RS35040
gene id: 1265868:SRIM_RS35040
uniprot id: L8ET59
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS40475
gene id: 1265868:SRIM_RS40475
uniprot id: A0A8A1V0G1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1265868:SRIM RS35585
gene id: 1265868:SRIM_RS35585
uniprot id: L8EPF5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1265868:SRIM RS28005
gene id: 1265868:SRIM_RS28005
uniprot id: A0A8A1V024
names: Subcellular Location Annotation
messages: Cell membrane

1265868:SRIM RS33590
gene id: 1265868:SRIM_RS33590
uniprot id: L8ERR1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1265868:SRIM RS29175
gene id: 1265868:SRIM_RS29175
uniprot id: L8EIB8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1265868:SRIM RS08630
gene id: 1265868:SRIM_RS08630
uniprot id: A0A8A1UZ47
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

1265868:SRIM RS39910
gene id: 1265868:SRIM_RS39910
uniprot id: L8EXJ4
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

1265868:SRIM RS13955
gene id: 1265868:SRIM_RS13955
uniprot id: A0A8A1UQK9
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1265868:SRIM RS12445
gene id: 1265868:SRIM_RS12445
uniprot id: L8ELD7
names: Similarity
messages: Belongs to the cytochrome P450 family.

1265868:SRIM RS06780
gene id: 1265868:SRIM_RS06780
uniprot id: L8EJ36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1265868:SRIM RS07590
gene id: 1265868:SRIM_RS07590
uniprot id: L8EIG6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1265868:SRIM RS30060
gene id: 1265868:SRIM_RS30060
uniprot id: L8EWV5
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

1265868:SRIM RS34625
gene id: 1265868:SRIM_RS34625
uniprot id: L8EDH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

1265868:SRIM RS22825
gene id: 1265868:SRIM_RS22825
uniprot id: L8ENH2
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

1265868:SRIM RS15570
gene id: 1265868:SRIM_RS15570
uniprot id: L8EKQ0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1265868:SRIM RS34300
gene id: 1265868:SRIM_RS34300
uniprot id: A0A8A1UWL1
names: Similarity
messages: Belongs to the cytochrome P450 family.

1265868:SRIM RS15625
gene id: 1265868:SRIM_RS15625
uniprot id: L8EKC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

1265868:SRIM RS36385
gene id: 1265868:SRIM_RS36385
uniprot id: L8EV35
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1265868:SRIM RS07540
gene id: 1265868:SRIM_RS07540
uniprot id: L8ED52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS13855
gene id: 1265868:SRIM_RS13855
uniprot id: L8EF64
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1265868:SRIM RS39190
gene id: 1265868:SRIM_RS39190
uniprot id: L8F016
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS13475
gene id: 1265868:SRIM_RS13475
uniprot id: A0A8A1UJX2
names: Similarity
messages: Belongs to the Fur family.

1265868:SRIM RS18485
gene id: 1265868:SRIM_RS18485
uniprot id: L8EEL1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1265868:SRIM RS08200
gene id: 1265868:SRIM_RS08200
uniprot id: L8ERD9
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS41890
gene id: 1265868:SRIM_RS41890
uniprot id: L8F122
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1265868:SRIM RS36130
gene id: 1265868:SRIM_RS36130
uniprot id: A0A8A1V2W9
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1265868:SRIM RS18650
gene id: 1265868:SRIM_RS18650
uniprot id: L8EUC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1265868:SRIM RS19565
gene id: 1265868:SRIM_RS19565
uniprot id: L8EUV6
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1265868:SRIM RS03245
gene id: 1265868:SRIM_RS03245
uniprot id: L8EDS0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1265868:SRIM RS30205
gene id: 1265868:SRIM_RS30205
uniprot id: L8EEI5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1265868:SRIM RS08460
gene id: 1265868:SRIM_RS08460
uniprot id: L8EGY8
names: Similarity
messages: Belongs to the IucA/IucC family.

1265868:SRIM RS31665
gene id: 1265868:SRIM_RS31665
uniprot id: L8EZA8
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1265868:SRIM RS05105
gene id: 1265868:SRIM_RS05105
uniprot id: A0A8A1ULS5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1265868:SRIM RS28855
gene id: 1265868:SRIM_RS28855
uniprot id: L8EGJ1
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1265868:SRIM RS28410
gene id: 1265868:SRIM_RS28410
uniprot id: L8EXW4
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1265868:SRIM RS10605
gene id: 1265868:SRIM_RS10605
uniprot id: L8EMY7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS38920
gene id: 1265868:SRIM_RS38920
uniprot id: L8EVM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Fes family.
messages: Cytoplasm

1265868:SRIM RS08520
gene id: 1265868:SRIM_RS08520
uniprot id: L8EKX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protease inhibitor I16 (SSI) family.
messages: Homodimer.
messages: Secreted
messages: Strong inhibitor of bacterial serine proteases such as subtilisin.

1265868:SRIM RS26535
gene id: 1265868:SRIM_RS26535
uniprot id: L8EPP1
names: Similarity
messages: Belongs to the GSP E family.

1265868:SRIM RS13580
gene id: 1265868:SRIM_RS13580
uniprot id: L8EL81
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS09260
gene id: 1265868:SRIM_RS09260
uniprot id: L8ED77
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1265868:SRIM RS25825
gene id: 1265868:SRIM_RS25825
uniprot id: L8EGU8
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

1265868:SRIM RS17005
gene id: 1265868:SRIM_RS17005
uniprot id: L8F2E1
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1265868:SRIM RS14020
gene id: 1265868:SRIM_RS14020
uniprot id: L8ELJ5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1265868:SRIM RS35370
gene id: 1265868:SRIM_RS35370
uniprot id: L8EN09
names: Similarity
messages: Belongs to the glutamine synthetase family.

1265868:SRIM RS25030
gene id: 1265868:SRIM_RS25030
uniprot id: L8ESY4
names: Similarity
messages: Belongs to the cytochrome P450 family.

1265868:SRIM RS04230
gene id: 1265868:SRIM_RS04230
uniprot id: L8EMM9
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS25105
gene id: 1265868:SRIM_RS25105
uniprot id: L8ET00
names: Similarity
messages: Belongs to the citrate synthase family.

1265868:SRIM RS18630
gene id: 1265868:SRIM_RS18630
uniprot id: L8EUS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1265868:SRIM RS20660
gene id: 1265868:SRIM_RS20660
uniprot id: L8F0L1
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS30180
gene id: 1265868:SRIM_RS30180
uniprot id: L8ED53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1265868:SRIM RS08710
gene id: 1265868:SRIM_RS08710
uniprot id: L8EFI2
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1265868:SRIM RS31910
gene id: 1265868:SRIM_RS31910
uniprot id: L8EUJ5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1265868:SRIM RS18710
gene id: 1265868:SRIM_RS18710
uniprot id: L8ETH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1265868:SRIM RS20515
gene id: 1265868:SRIM_RS20515
uniprot id: L8EZ25
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1265868:SRIM RS06885
gene id: 1265868:SRIM_RS06885
uniprot id: A0A8A1UIR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1265868:SRIM RS26105
gene id: 1265868:SRIM_RS26105
uniprot id: L8EI75
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1265868:SRIM RS14035
gene id: 1265868:SRIM_RS14035
uniprot id: L8ER01
names: Similarity
messages: Belongs to the ArsC family.

1265868:SRIM RS25620
gene id: 1265868:SRIM_RS25620
uniprot id: L8END0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1265868:SRIM RS26845
gene id: 1265868:SRIM_RS26845
uniprot id: L8ES76
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1265868:SRIM RS42440
gene id: 1265868:SRIM_RS42440
uniprot id: L8EEL5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1265868:SRIM RS05340
gene id: 1265868:SRIM_RS05340
uniprot id: L8EDG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1265868:SRIM RS09285
gene id: 1265868:SRIM_RS09285
uniprot id: L8EI92
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

1265868:SRIM RS13470
gene id: 1265868:SRIM_RS13470
uniprot id: L8EVM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS27005
gene id: 1265868:SRIM_RS27005
uniprot id: L8EV51
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MshB deacetylase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.

1265868:SRIM RS18705
gene id: 1265868:SRIM_RS18705
uniprot id: L8EUQ2
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1265868:SRIM RS30545
gene id: 1265868:SRIM_RS30545
uniprot id: L8EM92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1265868:SRIM RS21580
gene id: 1265868:SRIM_RS21580
uniprot id: L8F1I6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1265868:SRIM RS07795
gene id: 1265868:SRIM_RS07795
uniprot id: L8ESX0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Monomer.

1265868:SRIM RS29550
gene id: 1265868:SRIM_RS29550
uniprot id: L8EIZ2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1265868:SRIM RS08980
gene id: 1265868:SRIM_RS08980
uniprot id: L8EDT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS35055
gene id: 1265868:SRIM_RS35055
uniprot id: L8ET60
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1265868:SRIM RS34490
gene id: 1265868:SRIM_RS34490
uniprot id: L8EMU6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1265868:SRIM RS24010
gene id: 1265868:SRIM_RS24010
uniprot id: L8EFS8
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1265868:SRIM RS25110
gene id: 1265868:SRIM_RS25110
uniprot id: A0A8A1UYF0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

1265868:SRIM RS18435
gene id: 1265868:SRIM_RS18435
uniprot id: A0A8A1UST3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1265868:SRIM RS27685
gene id: 1265868:SRIM_RS27685
uniprot id: L8EIF5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1265868:SRIM RS04280
gene id: 1265868:SRIM_RS04280
uniprot id: L8EGP0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1265868:SRIM RS03690
gene id: 1265868:SRIM_RS03690
uniprot id: L8EEK0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1265868:SRIM RS10535
gene id: 1265868:SRIM_RS10535
uniprot id: L8ELW1
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

1265868:SRIM RS25005
gene id: 1265868:SRIM_RS25005
uniprot id: L8ESX7
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

1265868:SRIM RS25910
gene id: 1265868:SRIM_RS25910
uniprot id: L8EJE1
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

1265868:SRIM RS19235
gene id: 1265868:SRIM_RS19235
uniprot id: L8EFF6
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS27785
gene id: 1265868:SRIM_RS27785
uniprot id: A0A8A1V0B2
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1265868:SRIM RS29345
gene id: 1265868:SRIM_RS29345
uniprot id: L8EIL9
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS28940
gene id: 1265868:SRIM_RS28940
uniprot id: L8EP08
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1265868:SRIM RS07530
gene id: 1265868:SRIM_RS07530
uniprot id: L8EL92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1265868:SRIM RS14155
gene id: 1265868:SRIM_RS14155
uniprot id: L8ERH5
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

1265868:SRIM RS31265
gene id: 1265868:SRIM_RS31265
uniprot id: L8EI62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1265868:SRIM RS17035
gene id: 1265868:SRIM_RS17035
uniprot id: L8EYK0
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase involved in purine salvage.

1265868:SRIM RS22955
gene id: 1265868:SRIM_RS22955
uniprot id: L8ET39
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1265868:SRIM RS18675
gene id: 1265868:SRIM_RS18675
uniprot id: L8EUB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1265868:SRIM RS33015
gene id: 1265868:SRIM_RS33015
uniprot id: A0A8A1UYF1
names: Similarity
messages: Belongs to the hyi family.

1265868:SRIM RS22870
gene id: 1265868:SRIM_RS22870
uniprot id: A0A8A1UVH7
names: Similarity
messages: Belongs to the DNA photolyase family.

1265868:SRIM RS36630
gene id: 1265868:SRIM_RS36630
uniprot id: L8ED89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1265868:SRIM RS23610
gene id: 1265868:SRIM_RS23610
uniprot id: L8ERE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1265868:SRIM RS09125
gene id: 1265868:SRIM_RS09125
uniprot id: L8EG64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1265868:SRIM RS29265
gene id: 1265868:SRIM_RS29265
uniprot id: L8EFK7
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1265868:SRIM RS30595
gene id: 1265868:SRIM_RS30595
uniprot id: L8EEC2
names: Subcellular Location Annotation
messages: Cell membrane

1265868:SRIM RS27610
gene id: 1265868:SRIM_RS27610
uniprot id: L8ESA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1265868:SRIM RS06845
gene id: 1265868:SRIM_RS06845
uniprot id: L8EJ63
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1265868:SRIM RS19500
gene id: 1265868:SRIM_RS19500
uniprot id: L8EW56
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1265868:SRIM RS33810
gene id: 1265868:SRIM_RS33810
uniprot id: L8ET86
names: Similarity
messages: Belongs to the arginase family.

1265868:SRIM RS18720
gene id: 1265868:SRIM_RS18720
uniprot id: L8ETH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1265868:SRIM RS19025
gene id: 1265868:SRIM_RS19025
uniprot id: L8ENN3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1265868:SRIM RS27990
gene id: 1265868:SRIM_RS27990
uniprot id: A0A8A1V598
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

1265868:SRIM RS34150
gene id: 1265868:SRIM_RS34150
uniprot id: L8ELU9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1265868:SRIM RS20195
gene id: 1265868:SRIM_RS20195
uniprot id: L8EXK2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS04775
gene id: 1265868:SRIM_RS04775
uniprot id: A0A8A1UGE1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1265868:SRIM RS19600
gene id: 1265868:SRIM_RS19600
uniprot id: L8EW31
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1265868:SRIM RS03910
gene id: 1265868:SRIM_RS03910
uniprot id: L8ELD8
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

1265868:SRIM RS03970
gene id: 1265868:SRIM_RS03970
uniprot id: L8ET53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1265868:SRIM RS19525
gene id: 1265868:SRIM_RS19525
uniprot id: L8EW50
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS18655
gene id: 1265868:SRIM_RS18655
uniprot id: L8EUR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1265868:SRIM RS26140
gene id: 1265868:SRIM_RS26140
uniprot id: L8ET41
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1265868:SRIM RS04805
gene id: 1265868:SRIM_RS04805
uniprot id: L8EJ16
names: Subcellular Location Annotation
messages: Cell membrane

1265868:SRIM RS29275
gene id: 1265868:SRIM_RS29275
uniprot id: A0A8A1USX3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS19000
gene id: 1265868:SRIM_RS19000
uniprot id: L8ENN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1265868:SRIM RS05835
gene id: 1265868:SRIM_RS05835
uniprot id: L8EG16
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

1265868:SRIM RS08970
gene id: 1265868:SRIM_RS08970
uniprot id: L8EEK4
names: Similarity
messages: Belongs to the UPF0098 family.

1265868:SRIM RS23480
gene id: 1265868:SRIM_RS23480
uniprot id: L8EJ80
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1265868:SRIM RS10010
gene id: 1265868:SRIM_RS10010
uniprot id: L8EL61
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1265868:SRIM RS28655
gene id: 1265868:SRIM_RS28655
uniprot id: L8EQQ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS03705
gene id: 1265868:SRIM_RS03705
uniprot id: L8EFN4
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1265868:SRIM RS12475
gene id: 1265868:SRIM_RS12475
uniprot id: L8EKD2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1265868:SRIM RS42060
gene id: 1265868:SRIM_RS42060
uniprot id: L8F071
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1265868:SRIM RS08415
gene id: 1265868:SRIM_RS08415
uniprot id: L8EGK4
names: Similarity
messages: Belongs to the DDAH family.

1265868:SRIM RS18815
gene id: 1265868:SRIM_RS18815
uniprot id: L8EXI7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1265868:SRIM RS04670
gene id: 1265868:SRIM_RS04670
uniprot id: L8EHB2
names: Similarity
messages: Belongs to the YciI family.

1265868:SRIM RS31270
gene id: 1265868:SRIM_RS31270
uniprot id: A0A8A1UW30
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1265868:SRIM RS21160
gene id: 1265868:SRIM_RS21160
uniprot id: L8F1J5
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS15670
gene id: 1265868:SRIM_RS15670
uniprot id: L8EEN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1265868:SRIM RS31250
gene id: 1265868:SRIM_RS31250
uniprot id: A0A8A1UZU5
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS36455
gene id: 1265868:SRIM_RS36455
uniprot id: A0A8A1UZ76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1265868:SRIM RS15810
gene id: 1265868:SRIM_RS15810
uniprot id: L8ES31
names: Similarity
messages: Belongs to the peptidase C56 family.

1265868:SRIM RS19480
gene id: 1265868:SRIM_RS19480
uniprot id: L8EUV7
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

1265868:SRIM RS10890
gene id: 1265868:SRIM_RS10890
uniprot id: L8EQM8
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1265868:SRIM RS26665
gene id: 1265868:SRIM_RS26665
uniprot id: A0A8A1UYQ3
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS28745
gene id: 1265868:SRIM_RS28745
uniprot id: L8ES06
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS08720
gene id: 1265868:SRIM_RS08720
uniprot id: A0A8A1UI98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1265868:SRIM RS05920
gene id: 1265868:SRIM_RS05920
uniprot id: A0A8A1UIK0
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1265868:SRIM RS11490
gene id: 1265868:SRIM_RS11490
uniprot id: L8EF82
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1265868:SRIM RS10825
gene id: 1265868:SRIM_RS10825
uniprot id: L8ERY6
names: Caution
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

1265868:SRIM RS39800
gene id: 1265868:SRIM_RS39800
uniprot id: A0A8A1UZ46
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M7 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Secreted

1265868:SRIM RS15875
gene id: 1265868:SRIM_RS15875
uniprot id: L8EVH1
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1265868:SRIM RS17235
gene id: 1265868:SRIM_RS17235
uniprot id: L8EXT7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An FAD-requiring monooxygenase active on some tetracycline antibiotic derivatives, which leads to their inactivation. Hydroxylates carbon 11a of tetracycline and some analogs.
messages: Belongs to the aromatic-ring hydroxylase family. TetX subfamily.
messages: Consists of an N-terminal FAD-binding domain with a Rossman fold and a C-terminal substrate-binding domain.
messages: Cytoplasm
messages: Monomer.

1265868:SRIM RS12870
gene id: 1265868:SRIM_RS12870
uniprot id: A0A8A1V092
names: Similarity
messages: Belongs to the pirin family.

1265868:SRIM RS08795
gene id: 1265868:SRIM_RS08795
uniprot id: L8EFH9
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS22425
gene id: 1265868:SRIM_RS22425
uniprot id: A0A8A1UWR9
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

1265868:SRIM RS32920
gene id: 1265868:SRIM_RS32920
uniprot id: L8EPL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Mediates magnesium influx to the cytosol.

1265868:SRIM RS18855
gene id: 1265868:SRIM_RS18855
uniprot id: L8EU71
names: Similarity
messages: Belongs to the UPF0336 family.

1265868:SRIM RS23735
gene id: 1265868:SRIM_RS23735
uniprot id: L8EQA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1265868:SRIM RS18725
gene id: 1265868:SRIM_RS18725
uniprot id: L8EUA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1265868:SRIM RS40120
gene id: 1265868:SRIM_RS40120
uniprot id: A0A8A1V0A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1265868:SRIM RS39300
gene id: 1265868:SRIM_RS39300
uniprot id: A0A8A1V1I9
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

1265868:SRIM RS16320
gene id: 1265868:SRIM_RS16320
uniprot id: L8ELN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1265868:SRIM RS24105
gene id: 1265868:SRIM_RS24105
uniprot id: L8EGB6
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

1265868:SRIM RS18610
gene id: 1265868:SRIM_RS18610
uniprot id: L8ETJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1265868:SRIM RS15680
gene id: 1265868:SRIM_RS15680
uniprot id: L8EFH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

1265868:SRIM RS22580
gene id: 1265868:SRIM_RS22580
uniprot id: L8EP00
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1265868:SRIM RS13660
gene id: 1265868:SRIM_RS13660
uniprot id: L8ELF9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1265868:SRIM RS18700
gene id: 1265868:SRIM_RS18700
uniprot id: L8EUA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1265868:SRIM RS18285
gene id: 1265868:SRIM_RS18285
uniprot id: L8EPE6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1265868:SRIM RS34865
gene id: 1265868:SRIM_RS34865
uniprot id: L8EHZ6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1265868:SRIM RS07890
gene id: 1265868:SRIM_RS07890
uniprot id: L8EJ73
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

1265868:SRIM RS20035
gene id: 1265868:SRIM_RS20035
uniprot id: L8EVT3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1265868:SRIM RS06875
gene id: 1265868:SRIM_RS06875
uniprot id: L8ENE8
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1265868:SRIM RS34830
gene id: 1265868:SRIM_RS34830
uniprot id: L8EJ35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

1265868:SRIM RS07595
gene id: 1265868:SRIM_RS07595
uniprot id: L8EIV5
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS13220
gene id: 1265868:SRIM_RS13220
uniprot id: L8EFD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS22540
gene id: 1265868:SRIM_RS22540
uniprot id: L8EJ90
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1265868:SRIM RS29610
gene id: 1265868:SRIM_RS29610
uniprot id: L8EF51
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1265868:SRIM RS27910
gene id: 1265868:SRIM_RS27910
uniprot id: L8EKS1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1265868:SRIM RS09320
gene id: 1265868:SRIM_RS09320
uniprot id: L8EF02
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS28785
gene id: 1265868:SRIM_RS28785
uniprot id: L8ER93
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

1265868:SRIM RS32365
gene id: 1265868:SRIM_RS32365
uniprot id: L8EIP6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1265868:SRIM RS36745
gene id: 1265868:SRIM_RS36745
uniprot id: L8EJD0
names: Similarity
messages: Belongs to the cytochrome P450 family.

1265868:SRIM RS35750
gene id: 1265868:SRIM_RS35750
uniprot id: A0A8A1UYF5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1265868:SRIM RS11390
gene id: 1265868:SRIM_RS11390
uniprot id: L8EI72
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS15390
gene id: 1265868:SRIM_RS15390
uniprot id: L8EF79
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1265868:SRIM RS03275
gene id: 1265868:SRIM_RS03275
uniprot id: L8EHV2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1265868:SRIM RS16525
gene id: 1265868:SRIM_RS16525
uniprot id: L8EG05
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1265868:SRIM RS23865
gene id: 1265868:SRIM_RS23865
uniprot id: L8ENM4
names: Subcellular Location Annotation
messages: Cell membrane

1265868:SRIM RS30445
gene id: 1265868:SRIM_RS30445
uniprot id: L8ERH1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

1265868:SRIM RS05260
gene id: 1265868:SRIM_RS05260
uniprot id: L8EMP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1265868:SRIM RS08845
gene id: 1265868:SRIM_RS08845
uniprot id: L8EN46
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS29110
gene id: 1265868:SRIM_RS29110
uniprot id: L8EIC6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS28310
gene id: 1265868:SRIM_RS28310
uniprot id: L8EXX6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS30085
gene id: 1265868:SRIM_RS30085
uniprot id: L8EWV1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1265868:SRIM RS25735
gene id: 1265868:SRIM_RS25735
uniprot id: L8EN33
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS38280
gene id: 1265868:SRIM_RS38280
uniprot id: A0A8A1UX37
names: Similarity
messages: Belongs to the cytochrome P450 family.

1265868:SRIM RS01100
gene id: 1265868:SRIM_RS01100
uniprot id: L8EXR1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1265868:SRIM RS36570
gene id: 1265868:SRIM_RS36570
uniprot id: L8EYI4
names: Similarity
messages: Belongs to the glycosyl hydrolase 12 (cellulase H) family.

1265868:SRIM RS09355
gene id: 1265868:SRIM_RS09355
uniprot id: A0A8A1UNB7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1265868:SRIM RS15080
gene id: 1265868:SRIM_RS15080
uniprot id: L8EIM8
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

1265868:SRIM RS34405
gene id: 1265868:SRIM_RS34405
uniprot id: A0A8A1V237
names: Similarity
messages: Belongs to the cytochrome P450 family.

1265868:SRIM RS30200
gene id: 1265868:SRIM_RS30200
uniprot id: L8EEP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1265868:SRIM RS21700
gene id: 1265868:SRIM_RS21700
uniprot id: L8F1W3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS09600
gene id: 1265868:SRIM_RS09600
uniprot id: L8EF93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS21395
gene id: 1265868:SRIM_RS21395
uniprot id: L8F0M7
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

1265868:SRIM RS13740
gene id: 1265868:SRIM_RS13740
uniprot id: A0A8A1UZ44
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

1265868:SRIM RS28535
gene id: 1265868:SRIM_RS28535
uniprot id: L8EU48
names: Similarity
messages: Belongs to the UPF0045 family.

1265868:SRIM RS07705
gene id: 1265868:SRIM_RS07705
uniprot id: L8ESY3
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

1265868:SRIM RS08540
gene id: 1265868:SRIM_RS08540
uniprot id: L8EJN5
names: Similarity
messages: Belongs to the peptidase S1 family.

1265868:SRIM RS13950
gene id: 1265868:SRIM_RS13950
uniprot id: L8EJ74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1265868:SRIM RS13140
gene id: 1265868:SRIM_RS13140
uniprot id: A0A8A1UNB0
names: Similarity
messages: Belongs to the FGGY kinase family.

1265868:SRIM RS19060
gene id: 1265868:SRIM_RS19060
uniprot id: L8EMR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1265868:SRIM RS24695
gene id: 1265868:SRIM_RS24695
uniprot id: L8ETX6
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1265868:SRIM RS19705
gene id: 1265868:SRIM_RS19705
uniprot id: L8EWS7
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS26320
gene id: 1265868:SRIM_RS26320
uniprot id: L8ESU5
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1265868:SRIM RS18905
gene id: 1265868:SRIM_RS18905
uniprot id: L8EJA9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS25500
gene id: 1265868:SRIM_RS25500
uniprot id: L8EKG6
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1265868:SRIM RS08755
gene id: 1265868:SRIM_RS08755
uniprot id: A0A8A1UK09
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1265868:SRIM RS12555
gene id: 1265868:SRIM_RS12555
uniprot id: L8EZ04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

1265868:SRIM RS20545
gene id: 1265868:SRIM_RS20545
uniprot id: L8EYJ2
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS23665
gene id: 1265868:SRIM_RS23665
uniprot id: L8EQB3
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1265868:SRIM RS14005
gene id: 1265868:SRIM_RS14005
uniprot id: L8ELR3
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1265868:SRIM RS27550
gene id: 1265868:SRIM_RS27550
uniprot id: L8EP98
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1265868:SRIM RS27135
gene id: 1265868:SRIM_RS27135
uniprot id: L8EKL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1265868:SRIM RS09070
gene id: 1265868:SRIM_RS09070
uniprot id: L8EH42
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS23160
gene id: 1265868:SRIM_RS23160
uniprot id: L8ETP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1265868:SRIM RS34310
gene id: 1265868:SRIM_RS34310
uniprot id: L8EV36
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1265868:SRIM RS21655
gene id: 1265868:SRIM_RS21655
uniprot id: L8F1K4
names: Function
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: May catalyze the transamination reaction in phenylalanine biosynthesis.

1265868:SRIM RS29835
gene id: 1265868:SRIM_RS29835
uniprot id: A0A8A1UTZ2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1265868:SRIM RS34505
gene id: 1265868:SRIM_RS34505
uniprot id: L8ER60
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

1265868:SRIM RS37065
gene id: 1265868:SRIM_RS37065
uniprot id: L8EVF5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1265868:SRIM RS15420
gene id: 1265868:SRIM_RS15420
uniprot id: A0A8A1ULT8
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS28260
gene id: 1265868:SRIM_RS28260
uniprot id: A0A8A1UZE2
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1265868:SRIM RS18785
gene id: 1265868:SRIM_RS18785
uniprot id: L8ETF8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1265868:SRIM RS38890
gene id: 1265868:SRIM_RS38890
uniprot id: L8ERD1
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.

1265868:SRIM RS21205
gene id: 1265868:SRIM_RS21205
uniprot id: L8F0I9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

1265868:SRIM RS09055
gene id: 1265868:SRIM_RS09055
uniprot id: L8EG49
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1265868:SRIM RS31935
gene id: 1265868:SRIM_RS31935
uniprot id: A0A8A1UYW0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1265868:SRIM RS30240
gene id: 1265868:SRIM_RS30240
uniprot id: L8EPV8
names: Similarity
messages: Belongs to the WXG100 family.

1265868:SRIM RS01240
gene id: 1265868:SRIM_RS01240
uniprot id: L8EVQ0
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1265868:SRIM RS09810
gene id: 1265868:SRIM_RS09810
uniprot id: L8EL78
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1265868:SRIM RS09645
gene id: 1265868:SRIM_RS09645
uniprot id: L8EJG8
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1265868:SRIM RS20440
gene id: 1265868:SRIM_RS20440
uniprot id: L8EZ12
names: Similarity
messages: Belongs to the peptidase S11 family.

1265868:SRIM RS12890
gene id: 1265868:SRIM_RS12890
uniprot id: L8EYI0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1265868:SRIM RS02450
gene id: 1265868:SRIM_RS02450
uniprot id: L8F072
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1265868:SRIM RS34590
gene id: 1265868:SRIM_RS34590
uniprot id: L8EMT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

1265868:SRIM RS06835
gene id: 1265868:SRIM_RS06835
uniprot id: L8EK13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1265868:SRIM RS29685
gene id: 1265868:SRIM_RS29685
uniprot id: L8EEM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1265868:SRIM RS16150
gene id: 1265868:SRIM_RS16150
uniprot id: L8EN10
names: Subcellular Location Annotation
messages: Cell membrane

1265868:SRIM RS24760
gene id: 1265868:SRIM_RS24760
uniprot id: L8ELF2
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS23635
gene id: 1265868:SRIM_RS23635
uniprot id: L8ERE0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1265868:SRIM RS14755
gene id: 1265868:SRIM_RS14755
uniprot id: L8EP78
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1265868:SRIM RS30965
gene id: 1265868:SRIM_RS30965
uniprot id: L8EQ91
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1265868:SRIM RS24990
gene id: 1265868:SRIM_RS24990
uniprot id: L8EW82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS11750
gene id: 1265868:SRIM_RS11750
uniprot id: L8EY86
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1265868:SRIM RS06220
gene id: 1265868:SRIM_RS06220
uniprot id: L8EL34
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1265868:SRIM RS33640
gene id: 1265868:SRIM_RS33640
uniprot id: L8ETP2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

1265868:SRIM RS29810
gene id: 1265868:SRIM_RS29810
uniprot id: L8F0Y4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1265868:SRIM RS07050
gene id: 1265868:SRIM_RS07050
uniprot id: L8EHP6
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1265868:SRIM RS08305
gene id: 1265868:SRIM_RS08305
uniprot id: L8EJC7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the homogentisate dioxygenase family.
messages: Hexamer; dimer of trimers.
messages: Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS36445
gene id: 1265868:SRIM_RS36445
uniprot id: A0A8A1UV20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

1265868:SRIM RS10640
gene id: 1265868:SRIM_RS10640
uniprot id: A0A8A1UM31
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1265868:SRIM RS22845
gene id: 1265868:SRIM_RS22845
uniprot id: L8EJ79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

1265868:SRIM RS24715
gene id: 1265868:SRIM_RS24715
uniprot id: A0A8A1UQQ5
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

1265868:SRIM RS28935
gene id: 1265868:SRIM_RS28935
uniprot id: L8ETC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1265868:SRIM RS28025
gene id: 1265868:SRIM_RS28025
uniprot id: L8EKW9
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1265868:SRIM RS06645
gene id: 1265868:SRIM_RS06645
uniprot id: L8EQI9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1265868:SRIM RS38455
gene id: 1265868:SRIM_RS38455
uniprot id: L8EVZ5
names: Similarity
messages: Belongs to the PrpD family.

1265868:SRIM RS23640
gene id: 1265868:SRIM_RS23640
uniprot id: L8EQB8
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1265868:SRIM RS18890
gene id: 1265868:SRIM_RS18890
uniprot id: L8EG76
names: Similarity
messages: Belongs to the UPF0234 family.

1265868:SRIM RS03080
gene id: 1265868:SRIM_RS03080
uniprot id: L8ERP1
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1265868:SRIM RS11535
gene id: 1265868:SRIM_RS11535
uniprot id: A0A8A1UL21
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DyP-type peroxidase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.

1265868:SRIM RS06950
gene id: 1265868:SRIM_RS06950
uniprot id: L8EN37
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1265868:SRIM RS19075
gene id: 1265868:SRIM_RS19075
uniprot id: L8ENL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1265868:SRIM RS28690
gene id: 1265868:SRIM_RS28690
uniprot id: L8ESB0
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS22430
gene id: 1265868:SRIM_RS22430
uniprot id: L8EKH9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1265868:SRIM RS27690
gene id: 1265868:SRIM_RS27690
uniprot id: A0A8A1US54
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

1265868:SRIM RS14495
gene id: 1265868:SRIM_RS14495
uniprot id: L8EXX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1265868:SRIM RS04555
gene id: 1265868:SRIM_RS04555
uniprot id: L8EGZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1265868:SRIM RS19940
gene id: 1265868:SRIM_RS19940
uniprot id: A0A8A1URR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1265868:SRIM RS22780
gene id: 1265868:SRIM_RS22780
uniprot id: L8EKG3
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1265868:SRIM RS24915
gene id: 1265868:SRIM_RS24915
uniprot id: L8EEP2
names: Subcellular Location Annotation
messages: Cell membrane

1265868:SRIM RS16110
gene id: 1265868:SRIM_RS16110
uniprot id: L8EMP8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1265868:SRIM RS20585
gene id: 1265868:SRIM_RS20585
uniprot id: A0A8A1V5E0
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1265868:SRIM RS15170
gene id: 1265868:SRIM_RS15170
uniprot id: L8EJP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1265868:SRIM RS10465
gene id: 1265868:SRIM_RS10465
uniprot id: L8EEZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1265868:SRIM RS15560
gene id: 1265868:SRIM_RS15560
uniprot id: L8EJF8
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS29955
gene id: 1265868:SRIM_RS29955
uniprot id: L8EXR3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1265868:SRIM RS35860
gene id: 1265868:SRIM_RS35860
uniprot id: L8ERK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS33360
gene id: 1265868:SRIM_RS33360
uniprot id: L8EPW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS40200
gene id: 1265868:SRIM_RS40200
uniprot id: L8EXN4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1265868:SRIM RS14290
gene id: 1265868:SRIM_RS14290
uniprot id: L8ERQ6
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1265868:SRIM RS16235
gene id: 1265868:SRIM_RS16235
uniprot id: L8EGR4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS06815
gene id: 1265868:SRIM_RS06815
uniprot id: L8EKE2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1265868:SRIM RS16760
gene id: 1265868:SRIM_RS16760
uniprot id: L8EYT0
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS00295
gene id: 1265868:SRIM_RS00295
uniprot id: L8EZQ7
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1265868:SRIM RS39315
gene id: 1265868:SRIM_RS39315
uniprot id: A0A8A1V4S9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1265868:SRIM RS32570
gene id: 1265868:SRIM_RS32570
uniprot id: L8ER73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1265868:SRIM RS34180
gene id: 1265868:SRIM_RS34180
uniprot id: A0A8A1V1D3
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1265868:SRIM RS18715
gene id: 1265868:SRIM_RS18715
uniprot id: L8EXK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1265868:SRIM RS18255
gene id: 1265868:SRIM_RS18255
uniprot id: L8EP85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily.
messages: Periplasm

1265868:SRIM RS34780
gene id: 1265868:SRIM_RS34780
uniprot id: L8EEY4
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1265868:SRIM RS13615
gene id: 1265868:SRIM_RS13615
uniprot id: L8EKB2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1265868:SRIM RS24755
gene id: 1265868:SRIM_RS24755
uniprot id: L8EL64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS29790
gene id: 1265868:SRIM_RS29790
uniprot id: L8EX07
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1265868:SRIM RS24795
gene id: 1265868:SRIM_RS24795
uniprot id: L8EPF7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1265868:SRIM RS06380
gene id: 1265868:SRIM_RS06380
uniprot id: L8EE33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1265868:SRIM RS12815
gene id: 1265868:SRIM_RS12815
uniprot id: L8EYG4
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS09345
gene id: 1265868:SRIM_RS09345
uniprot id: L8EEZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PhyH family. EctD subfamily.
messages: Homodimer.
messages: Involved in the biosynthesis of 5-hydroxyectoine, called compatible solute, which helps organisms to survive extreme osmotic stress by acting as a highly soluble organic osmolyte. Catalyzes the 2-oxoglutarate-dependent selective hydroxylation of L-ectoine to yield (4S,5S)-5-hydroxyectoine.

1265868:SRIM RS15540
gene id: 1265868:SRIM_RS15540
uniprot id: L8EKP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1265868:SRIM RS29130
gene id: 1265868:SRIM_RS29130
uniprot id: A0A8A1UV46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Cytoplasm

1265868:SRIM RS08725
gene id: 1265868:SRIM_RS08725
uniprot id: A0A8A1UNM0
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

1265868:SRIM RS38485
gene id: 1265868:SRIM_RS38485
uniprot id: A0A8A1V156
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS10775
gene id: 1265868:SRIM_RS10775
uniprot id: A0A8A1UPM1
names: Similarity
messages: Belongs to the peptidase C40 family.

1265868:SRIM RS16680
gene id: 1265868:SRIM_RS16680
uniprot id: L8EYU2
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1265868:SRIM RS11240
gene id: 1265868:SRIM_RS11240
uniprot id: L8EPB2
names: Similarity
messages: Belongs to the cytochrome P450 family.

1265868:SRIM RS27730
gene id: 1265868:SRIM_RS27730
uniprot id: L8EHF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1265868:SRIM RS29740
gene id: 1265868:SRIM_RS29740
uniprot id: L8EX19
names: Similarity
messages: Belongs to the phosphopentomutase family.

1265868:SRIM RS14200
gene id: 1265868:SRIM_RS14200
uniprot id: L8EUT0
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1265868:SRIM RS15550
gene id: 1265868:SRIM_RS15550
uniprot id: L8EJC9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protease inhibitor I16 (SSI) family.
messages: Homodimer.
messages: Secreted

1265868:SRIM RS39440
gene id: 1265868:SRIM_RS39440
uniprot id: A0A8A1V361
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1265868:SRIM RS27875
gene id: 1265868:SRIM_RS27875
uniprot id: L8EJG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1265868:SRIM RS09625
gene id: 1265868:SRIM_RS09625
uniprot id: L8EF89
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1265868:SRIM RS40415
gene id: 1265868:SRIM_RS40415
uniprot id: L8F1A0
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

1265868:SRIM RS02265
gene id: 1265868:SRIM_RS02265
uniprot id: L8EYT6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1265868:SRIM RS11295
gene id: 1265868:SRIM_RS11295
uniprot id: L8EQD4
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1265868:SRIM RS14070
gene id: 1265868:SRIM_RS14070
uniprot id: L8EMW6
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.

1265868:SRIM RS27770
gene id: 1265868:SRIM_RS27770
uniprot id: A0A8A1UT29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1265868:SRIM RS31925
gene id: 1265868:SRIM_RS31925
uniprot id: A0A8A1V662
names: Similarity
messages: Belongs to the HIBADH-related family.

1265868:SRIM RS14105
gene id: 1265868:SRIM_RS14105
uniprot id: L8EMQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1265868:SRIM RS20770
gene id: 1265868:SRIM_RS20770
uniprot id: L8EXD1
names: Similarity
messages: Belongs to the peptidase M18 family.

1265868:SRIM RS39360
gene id: 1265868:SRIM_RS39360
uniprot id: A0A8A1UZY9
names: Similarity
messages: Belongs to the cytochrome P450 family.

1265868:SRIM RS29320
gene id: 1265868:SRIM_RS29320
uniprot id: L8EIM2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1265868:SRIM RS05315
gene id: 1265868:SRIM_RS05315
uniprot id: L8EIG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1265868:SRIM RS29575
gene id: 1265868:SRIM_RS29575
uniprot id: L8EIY7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1265868:SRIM RS09700
gene id: 1265868:SRIM_RS09700
uniprot id: A0A8A1UYU4
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

1265868:SRIM RS19290
gene id: 1265868:SRIM_RS19290
uniprot id: A0A8A1UQB9
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS33200
gene id: 1265868:SRIM_RS33200
uniprot id: L8EN79
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS31690
gene id: 1265868:SRIM_RS31690
uniprot id: L8EV89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1265868:SRIM RS09155
gene id: 1265868:SRIM_RS09155
uniprot id: L8EIG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

1265868:SRIM RS14115
gene id: 1265868:SRIM_RS14115
uniprot id: L8ER15
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1265868:SRIM RS07680
gene id: 1265868:SRIM_RS07680
uniprot id: L8ESY6
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

1265868:SRIM RS10240
gene id: 1265868:SRIM_RS10240
uniprot id: L8EJV4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1265868:SRIM RS09100
gene id: 1265868:SRIM_RS09100
uniprot id: L8EG59
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1265868:SRIM RS01110
gene id: 1265868:SRIM_RS01110
uniprot id: L8EUH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1265868:SRIM RS13775
gene id: 1265868:SRIM_RS13775
uniprot id: L8EJK1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS26085
gene id: 1265868:SRIM_RS26085
uniprot id: A0A8A1USD3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1265868:SRIM RS16930
gene id: 1265868:SRIM_RS16930
uniprot id: L8EZX2
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

1265868:SRIM RS09275
gene id: 1265868:SRIM_RS09275
uniprot id: L8EF60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Membrane

1265868:SRIM RS26250
gene id: 1265868:SRIM_RS26250
uniprot id: A0A8A1USF6
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

1265868:SRIM RS06655
gene id: 1265868:SRIM_RS06655
uniprot id: L8ETT1
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1265868:SRIM RS36590
gene id: 1265868:SRIM_RS36590
uniprot id: L8EUI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

1265868:SRIM RS12895
gene id: 1265868:SRIM_RS12895
uniprot id: L8EZP7
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1265868:SRIM RS34810
gene id: 1265868:SRIM_RS34810
uniprot id: L8EEY0
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1265868:SRIM RS07020
gene id: 1265868:SRIM_RS07020
uniprot id: L8EE72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

1265868:SRIM RS21890
gene id: 1265868:SRIM_RS21890
uniprot id: L8F4L6
names: Similarity
messages: Belongs to the SCO1/2 family.

1265868:SRIM RS34305
gene id: 1265868:SRIM_RS34305
uniprot id: L8EZ60
names: Similarity
messages: Belongs to the cytochrome P450 family.

1265868:SRIM RS16015
gene id: 1265868:SRIM_RS16015
uniprot id: L8ELH3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Bifunctional enzyme that catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives, and the FMNH2-dependent reduction of dehydro-F420-0 to form F420-0.
messages: Binds 2 divalent metal cations per subunit. The ions could be magnesium and/or manganese.
messages: In the N-terminal section; belongs to the CofE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monovalent cation. The ion could be potassium.

1265868:SRIM RS14300
gene id: 1265868:SRIM_RS14300
uniprot id: L8EUQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1265868:SRIM RS09795
gene id: 1265868:SRIM_RS09795
uniprot id: L8EIE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1265868:SRIM RS30755
gene id: 1265868:SRIM_RS30755
uniprot id: L8EL22
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1265868:SRIM RS33090
gene id: 1265868:SRIM_RS33090
uniprot id: L8EN99
names: Similarity
messages: Belongs to the malate synthase family.

1265868:SRIM RS27810
gene id: 1265868:SRIM_RS27810
uniprot id: A0A8A1UY20
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1265868:SRIM RS14125
gene id: 1265868:SRIM_RS14125
uniprot id: L8EMX4
names: Similarity
messages: Belongs to the peptidase M1 family.

1265868:SRIM RS32935
gene id: 1265868:SRIM_RS32935
uniprot id: L8ELI6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1265868:SRIM RS13965
gene id: 1265868:SRIM_RS13965
uniprot id: L8EHT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1265868:SRIM RS08320
gene id: 1265868:SRIM_RS08320
uniprot id: L8EMC2
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS07190
gene id: 1265868:SRIM_RS07190
uniprot id: L8ER14
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS07605
gene id: 1265868:SRIM_RS07605
uniprot id: L8ELU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1265868:SRIM RS32855
gene id: 1265868:SRIM_RS32855
uniprot id: L8EF17
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS27725
gene id: 1265868:SRIM_RS27725
uniprot id: L8ELT1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1265868:SRIM RS32230
gene id: 1265868:SRIM_RS32230
uniprot id: L8EK87
names: Similarity
messages: Belongs to the darcynin family.

1265868:SRIM RS14660
gene id: 1265868:SRIM_RS14660
uniprot id: L8EXA7
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1265868:SRIM RS20745
gene id: 1265868:SRIM_RS20745
uniprot id: A0A8A1US55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1265868:SRIM RS08055
gene id: 1265868:SRIM_RS08055
uniprot id: L8EVK5
names: Similarity
messages: Belongs to the cytochrome P450 family.

1265868:SRIM RS11465
gene id: 1265868:SRIM_RS11465
uniprot id: L8EI84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1265868:SRIM RS16415
gene id: 1265868:SRIM_RS16415
uniprot id: L8EQ25
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS21310
gene id: 1265868:SRIM_RS21310
uniprot id: L8F0C7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1265868:SRIM RS12535
gene id: 1265868:SRIM_RS12535
uniprot id: L8EKK3
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS07185
gene id: 1265868:SRIM_RS07185
uniprot id: A0A8A1V155
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1265868:SRIM RS33765
gene id: 1265868:SRIM_RS33765
uniprot id: L8ETM5
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1265868:SRIM RS33000
gene id: 1265868:SRIM_RS33000
uniprot id: L8EEE4
names: Similarity
messages: Belongs to the catalase family.

1265868:SRIM RS36740
gene id: 1265868:SRIM_RS36740
uniprot id: L8ENM3
names: Similarity
messages: Belongs to the LOG family.

1265868:SRIM RS16425
gene id: 1265868:SRIM_RS16425
uniprot id: A0A8A1ULW1
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1265868:SRIM RS23245
gene id: 1265868:SRIM_RS23245
uniprot id: L8EQ98
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1265868:SRIM RS38425
gene id: 1265868:SRIM_RS38425
uniprot id: A0A8A1UYJ5
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1265868:SRIM RS01690
gene id: 1265868:SRIM_RS01690
uniprot id: L8EW92
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS21455
gene id: 1265868:SRIM_RS21455
uniprot id: L8F1F7
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS15950
gene id: 1265868:SRIM_RS15950
uniprot id: L8EH83
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS08625
gene id: 1265868:SRIM_RS08625
uniprot id: L8EEE2
names: Function
names: Similarity
messages: Belongs to the gas vesicle protein type A family.
messages: Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth.

1265868:SRIM RS24720
gene id: 1265868:SRIM_RS24720
uniprot id: L8EHR3
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

1265868:SRIM RS32315
gene id: 1265868:SRIM_RS32315
uniprot id: L8EIN9
names: Similarity
messages: Belongs to the peptidase C56 family.

1265868:SRIM RS24185
gene id: 1265868:SRIM_RS24185
uniprot id: L8ESV3
names: Similarity
messages: Belongs to the cytochrome P450 family.

1265868:SRIM RS30540
gene id: 1265868:SRIM_RS30540
uniprot id: L8ENB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1265868:SRIM RS39640
gene id: 1265868:SRIM_RS39640
uniprot id: L8EIA8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

1265868:SRIM RS33300
gene id: 1265868:SRIM_RS33300
uniprot id: A0A8A1UX22
names: Similarity
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Homohexamer. The oligomerization is ATP-dependent.

1265868:SRIM RS04120
gene id: 1265868:SRIM_RS04120
uniprot id: L8ENX6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

1265868:SRIM RS30705
gene id: 1265868:SRIM_RS30705
uniprot id: L8EL12
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1265868:SRIM RS19100
gene id: 1265868:SRIM_RS19100
uniprot id: L8ELB3
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1265868:SRIM RS03855
gene id: 1265868:SRIM_RS03855
uniprot id: L8EQX1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1265868:SRIM RS16805
gene id: 1265868:SRIM_RS16805
uniprot id: L8EZZ4
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

1265868:SRIM RS25730
gene id: 1265868:SRIM_RS25730
uniprot id: L8EP67
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1265868:SRIM RS31030
gene id: 1265868:SRIM_RS31030
uniprot id: L8EQY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1265868:SRIM RS06955
gene id: 1265868:SRIM_RS06955
uniprot id: A0A8A1UJ14
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

1265868:SRIM RS09520
gene id: 1265868:SRIM_RS09520
uniprot id: A0A8A1V023
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

1265868:SRIM RS15530
gene id: 1265868:SRIM_RS15530
uniprot id: L8ENP8
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1265868:SRIM RS39050
gene id: 1265868:SRIM_RS39050
uniprot id: L8EIG3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1265868:SRIM RS28325
gene id: 1265868:SRIM_RS28325
uniprot id: L8EV37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1265868:SRIM RS04165
gene id: 1265868:SRIM_RS04165
uniprot id: L8ELA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS04195
gene id: 1265868:SRIM_RS04195
uniprot id: L8EQR0
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1265868:SRIM RS20570
gene id: 1265868:SRIM_RS20570
uniprot id: L8EYJ7
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1265868:SRIM RS10215
gene id: 1265868:SRIM_RS10215
uniprot id: L8EJU8
names: Similarity
messages: Belongs to the TrpC family.

1265868:SRIM RS27180
gene id: 1265868:SRIM_RS27180
uniprot id: L8EG94
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS28340
gene id: 1265868:SRIM_RS28340
uniprot id: L8ETX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1265868:SRIM RS30380
gene id: 1265868:SRIM_RS30380
uniprot id: L8EQR6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

1265868:SRIM RS07205
gene id: 1265868:SRIM_RS07205
uniprot id: L8EU74
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS22525
gene id: 1265868:SRIM_RS22525
uniprot id: L8EG55
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1265868:SRIM RS16630
gene id: 1265868:SRIM_RS16630
uniprot id: L8EPA0
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

1265868:SRIM RS18825
gene id: 1265868:SRIM_RS18825
uniprot id: L8EU78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1265868:SRIM RS13830
gene id: 1265868:SRIM_RS13830
uniprot id: L8EF61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1265868:SRIM RS07510
gene id: 1265868:SRIM_RS07510
uniprot id: L8EGZ1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1265868:SRIM RS34815
gene id: 1265868:SRIM_RS34815
uniprot id: L8EFR2
names: Similarity
messages: Belongs to the cytochrome P450 family.

1265868:SRIM RS10015
gene id: 1265868:SRIM_RS10015
uniprot id: L8EQJ8
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

1265868:SRIM RS28790
gene id: 1265868:SRIM_RS28790
uniprot id: L8ESC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

1265868:SRIM RS37910
gene id: 1265868:SRIM_RS37910
uniprot id: L8EZ57
names: Similarity
messages: Belongs to the asp23 family.

1265868:SRIM RS28390
gene id: 1265868:SRIM_RS28390
uniprot id: L8ETW1
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1265868:SRIM RS27575
gene id: 1265868:SRIM_RS27575
uniprot id: L8EP95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1265868:SRIM RS34680
gene id: 1265868:SRIM_RS34680
uniprot id: L8ELL7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1265868:SRIM RS16995
gene id: 1265868:SRIM_RS16995
uniprot id: L8EZW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1265868:SRIM RS19965
gene id: 1265868:SRIM_RS19965
uniprot id: L8EVU2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1265868:SRIM RS04700
gene id: 1265868:SRIM_RS04700
uniprot id: L8EG25
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1265868:SRIM RS25015
gene id: 1265868:SRIM_RS25015
uniprot id: L8EW88
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1265868:SRIM RS33625
gene id: 1265868:SRIM_RS33625
uniprot id: L8ESY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

1265868:SRIM RS01260
gene id: 1265868:SRIM_RS01260
uniprot id: A0A8A1UJV4
names: Similarity
messages: Belongs to the DszC flavin monooxygenase family.

1265868:SRIM RS18670
gene id: 1265868:SRIM_RS18670
uniprot id: L8ETJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1265868:SRIM RS26800
gene id: 1265868:SRIM_RS26800
uniprot id: L8ED57
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1265868:SRIM RS35330
gene id: 1265868:SRIM_RS35330
uniprot id: L8ERC5
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS22220
gene id: 1265868:SRIM_RS22220
uniprot id: L8EJ03
names: Similarity
messages: Belongs to the protease inhibitor I16 (SSI) family.

1265868:SRIM RS08215
gene id: 1265868:SRIM_RS08215
uniprot id: A0A8A1UI26
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS25850
gene id: 1265868:SRIM_RS25850
uniprot id: L8EDM7
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1265868:SRIM RS07285
gene id: 1265868:SRIM_RS07285
uniprot id: L8EPX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1265868:SRIM RS19975
gene id: 1265868:SRIM_RS19975
uniprot id: L8EX32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1265868:SRIM RS07785
gene id: 1265868:SRIM_RS07785
uniprot id: L8ETL8
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1265868:SRIM RS05800
gene id: 1265868:SRIM_RS05800
uniprot id: L8EDX3
names: Similarity
messages: Belongs to the asparagine synthetase family.

1265868:SRIM RS30360
gene id: 1265868:SRIM_RS30360
uniprot id: L8EPT6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1265868:SRIM RS36245
gene id: 1265868:SRIM_RS36245
uniprot id: L8ESN4
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1265868:SRIM RS32930
gene id: 1265868:SRIM_RS32930
uniprot id: L8ELA2
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.

1265868:SRIM RS16330
gene id: 1265868:SRIM_RS16330
uniprot id: L8EQ12
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1265868:SRIM RS08605
gene id: 1265868:SRIM_RS08605
uniprot id: L8EF96
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

1265868:SRIM RS25995
gene id: 1265868:SRIM_RS25995
uniprot id: L8EEC9
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS14880
gene id: 1265868:SRIM_RS14880
uniprot id: A0A8A1URM0
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1265868:SRIM RS11235
gene id: 1265868:SRIM_RS11235
uniprot id: L8ETE9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1265868:SRIM RS31320
gene id: 1265868:SRIM_RS31320
uniprot id: A0A8A1USV1
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1265868:SRIM RS09330
gene id: 1265868:SRIM_RS09330
uniprot id: L8EHQ6
names: Function
names: Similarity
messages: Belongs to the acetyltransferase family. EctA subfamily.
messages: Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.

1265868:SRIM RS13260
gene id: 1265868:SRIM_RS13260
uniprot id: L8EVH0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1265868:SRIM RS29905
gene id: 1265868:SRIM_RS29905
uniprot id: L8EXR9
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1265868:SRIM RS11420
gene id: 1265868:SRIM_RS11420
uniprot id: L8EJI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS08240
gene id: 1265868:SRIM_RS08240
uniprot id: L8EHY7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1265868:SRIM RS10500
gene id: 1265868:SRIM_RS10500
uniprot id: L8EDY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1265868:SRIM RS13405
gene id: 1265868:SRIM_RS13405
uniprot id: L8EWD4
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1265868:SRIM RS26760
gene id: 1265868:SRIM_RS26760
uniprot id: L8EI49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1265868:SRIM RS19310
gene id: 1265868:SRIM_RS19310
uniprot id: A0A8A1UT94
names: Similarity
messages: Belongs to the AHA1 family.

1265868:SRIM RS35525
gene id: 1265868:SRIM_RS35525
uniprot id: A0A8A1UY54
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

1265868:SRIM RS16755
gene id: 1265868:SRIM_RS16755
uniprot id: L8F004
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS33125
gene id: 1265868:SRIM_RS33125
uniprot id: L8EPB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

1265868:SRIM RS29185
gene id: 1265868:SRIM_RS29185
uniprot id: A0A8A1UV00
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

1265868:SRIM RS00865
gene id: 1265868:SRIM_RS00865
uniprot id: A0A8A1V4B5
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

1265868:SRIM RS18440
gene id: 1265868:SRIM_RS18440
uniprot id: L8EL15
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

1265868:SRIM RS10145
gene id: 1265868:SRIM_RS10145
uniprot id: L8EM36
names: Similarity
messages: Belongs to the glutamate synthase family.

1265868:SRIM RS05030
gene id: 1265868:SRIM_RS05030
uniprot id: L8EDU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1265868:SRIM RS07570
gene id: 1265868:SRIM_RS07570
uniprot id: L8EIV9
names: Similarity
messages: Belongs to the glutamine synthetase family.

1265868:SRIM RS20935
gene id: 1265868:SRIM_RS20935
uniprot id: L8EXR2
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1265868:SRIM RS15005
gene id: 1265868:SRIM_RS15005
uniprot id: L8EE21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS35255
gene id: 1265868:SRIM_RS35255
uniprot id: L8EFH8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1265868:SRIM RS00530
gene id: 1265868:SRIM_RS00530
uniprot id: L8EZL7
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

1265868:SRIM RS05365
gene id: 1265868:SRIM_RS05365
uniprot id: L8EGC0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

1265868:SRIM RS32525
gene id: 1265868:SRIM_RS32525
uniprot id: L8ELS5
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1265868:SRIM RS18840
gene id: 1265868:SRIM_RS18840
uniprot id: L8ETE7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1265868:SRIM RS30120
gene id: 1265868:SRIM_RS30120
uniprot id: L8EGY0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1265868:SRIM RS22980
gene id: 1265868:SRIM_RS22980
uniprot id: L8EX72
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1265868:SRIM RS05990
gene id: 1265868:SRIM_RS05990
uniprot id: L8EJW1
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS22985
gene id: 1265868:SRIM_RS22985
uniprot id: L8ET33
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1265868:SRIM RS02960
gene id: 1265868:SRIM_RS02960
uniprot id: L8EDG2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1265868:SRIM RS20635
gene id: 1265868:SRIM_RS20635
uniprot id: L8F0L8
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

1265868:SRIM RS25965
gene id: 1265868:SRIM_RS25965
uniprot id: L8EJ01
names: Similarity
names: Subunit
messages: Belongs to the CMP-NeuNAc synthase family.
messages: Belongs to the KdsC family.
messages: Homotetramer.

1265868:SRIM RS10885
gene id: 1265868:SRIM_RS10885
uniprot id: A0A8A1UJA7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1265868:SRIM RS07640
gene id: 1265868:SRIM_RS07640
uniprot id: A0A8A1UN27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1265868:SRIM RS26520
gene id: 1265868:SRIM_RS26520
uniprot id: L8EPF6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS26730
gene id: 1265868:SRIM_RS26730
uniprot id: L8EEG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1265868:SRIM RS27485
gene id: 1265868:SRIM_RS27485
uniprot id: L8EE90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS21445
gene id: 1265868:SRIM_RS21445
uniprot id: L8F0N8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1265868:SRIM RS17870
gene id: 1265868:SRIM_RS17870
uniprot id: L8EYA9
names: Subcellular Location Annotation
messages: Cell membrane

1265868:SRIM RS14310
gene id: 1265868:SRIM_RS14310
uniprot id: A0A8A1V1I6
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

1265868:SRIM RS01745
gene id: 1265868:SRIM_RS01745
uniprot id: A0A8A1UEX8
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.

1265868:SRIM RS03695
gene id: 1265868:SRIM_RS03695
uniprot id: L8EIK5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1265868:SRIM RS13890
gene id: 1265868:SRIM_RS13890
uniprot id: L8EE81
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1265868:SRIM RS40940
gene id: 1265868:SRIM_RS40940
uniprot id: L8EFG8
names: Similarity
messages: Belongs to the DszC flavin monooxygenase family.

1265868:SRIM RS08600
gene id: 1265868:SRIM_RS08600
uniprot id: L8EEE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gas vesicle protein type A family.
messages: Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure.
messages: gas vesicle membrane

1265868:SRIM RS10495
gene id: 1265868:SRIM_RS10495
uniprot id: A0A8A1UR97
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS39920
gene id: 1265868:SRIM_RS39920
uniprot id: L8F0P0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1265868:SRIM RS18160
gene id: 1265868:SRIM_RS18160
uniprot id: L8EPG3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1265868:SRIM RS18795
gene id: 1265868:SRIM_RS18795
uniprot id: L8ETF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1265868:SRIM RS24945
gene id: 1265868:SRIM_RS24945
uniprot id: L8ES25
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1265868:SRIM RS20245
gene id: 1265868:SRIM_RS20245
uniprot id: A0A8A1UZV9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1265868:SRIM RS27355
gene id: 1265868:SRIM_RS27355
uniprot id: L8EP45
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1265868:SRIM RS11075
gene id: 1265868:SRIM_RS11075
uniprot id: L8ENQ5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1265868:SRIM RS34005
gene id: 1265868:SRIM_RS34005
uniprot id: L8EHC5
names: Similarity
messages: Belongs to the YciI family.

1265868:SRIM RS05510
gene id: 1265868:SRIM_RS05510
uniprot id: L8EKZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

1265868:SRIM RS40305
gene id: 1265868:SRIM_RS40305
uniprot id: L8EY18
names: Similarity
messages: Belongs to the cytochrome P450 family.

1265868:SRIM RS09340
gene id: 1265868:SRIM_RS09340
uniprot id: L8EER1
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

1265868:SRIM RS06745
gene id: 1265868:SRIM_RS06745
uniprot id: L8EQK1
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1265868:SRIM RS05720
gene id: 1265868:SRIM_RS05720
uniprot id: L8ERP7
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

1265868:SRIM RS00330
gene id: 1265868:SRIM_RS00330
uniprot id: A0A8A1UIR4
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS35645
gene id: 1265868:SRIM_RS35645
uniprot id: L8EP93
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1265868:SRIM RS17150
gene id: 1265868:SRIM_RS17150
uniprot id: L8EZS7
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

1265868:SRIM RS11025
gene id: 1265868:SRIM_RS11025
uniprot id: A0A8A1URJ1
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1265868:SRIM RS03890
gene id: 1265868:SRIM_RS03890
uniprot id: L8EML7
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1265868:SRIM RS22815
gene id: 1265868:SRIM_RS22815
uniprot id: L8EKF8
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1265868:SRIM RS16750
gene id: 1265868:SRIM_RS16750
uniprot id: L8EZF7
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS21875
gene id: 1265868:SRIM_RS21875
uniprot id: L8F208
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DyP-type peroxidase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.

1265868:SRIM RS35570
gene id: 1265868:SRIM_RS35570
uniprot id: L8EQB0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1265868:SRIM RS19160
gene id: 1265868:SRIM_RS19160
uniprot id: L8EKG9
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1265868:SRIM RS21865
gene id: 1265868:SRIM_RS21865
uniprot id: L8F4K9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

1265868:SRIM RS32710
gene id: 1265868:SRIM_RS32710
uniprot id: L8ES44
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1265868:SRIM RS24470
gene id: 1265868:SRIM_RS24470
uniprot id: L8EU46
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1265868:SRIM RS11615
gene id: 1265868:SRIM_RS11615
uniprot id: L8EU45
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1265868:SRIM RS30175
gene id: 1265868:SRIM_RS30175
uniprot id: L8EGC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1265868:SRIM RS13940
gene id: 1265868:SRIM_RS13940
uniprot id: L8EHU3
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS24485
gene id: 1265868:SRIM_RS24485
uniprot id: L8EU12
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1265868:SRIM RS36005
gene id: 1265868:SRIM_RS36005
uniprot id: L8EQH5
names: Similarity
messages: Belongs to the cytochrome P450 family.

1265868:SRIM RS06620
gene id: 1265868:SRIM_RS06620
uniprot id: L8EQI6
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS18525
gene id: 1265868:SRIM_RS18525
uniprot id: L8EUF6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS05305
gene id: 1265868:SRIM_RS05305
uniprot id: A0A8A1UI50
names: Similarity
messages: Belongs to the UPF0749 family.

1265868:SRIM RS01560
gene id: 1265868:SRIM_RS01560
uniprot id: L8EWB4
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS03810
gene id: 1265868:SRIM_RS03810
uniprot id: L8EGH7
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS31855
gene id: 1265868:SRIM_RS31855
uniprot id: L8EVV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

1265868:SRIM RS30960
gene id: 1265868:SRIM_RS30960
uniprot id: A0A8A1UZ41
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS18860
gene id: 1265868:SRIM_RS18860
uniprot id: L8EUL9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1265868:SRIM RS18845
gene id: 1265868:SRIM_RS18845
uniprot id: L8EXI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1265868:SRIM RS21260
gene id: 1265868:SRIM_RS21260
uniprot id: L8F0B8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1265868:SRIM RS17840
gene id: 1265868:SRIM_RS17840
uniprot id: A0A8A1UQM8
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1265868:SRIM RS06750
gene id: 1265868:SRIM_RS06750
uniprot id: L8EPI2
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

1265868:SRIM RS35975
gene id: 1265868:SRIM_RS35975
uniprot id: L8EQG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1265868:SRIM RS04570
gene id: 1265868:SRIM_RS04570
uniprot id: L8EED4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS18730
gene id: 1265868:SRIM_RS18730
uniprot id: L8EUP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1265868:SRIM RS39255
gene id: 1265868:SRIM_RS39255
uniprot id: L8EWX2
names: Similarity
messages: Belongs to the peptidase A31 family.

1265868:SRIM RS32745
gene id: 1265868:SRIM_RS32745
uniprot id: L8ENW0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1265868:SRIM RS00660
gene id: 1265868:SRIM_RS00660
uniprot id: A0A8A1V279
names: Similarity
messages: Belongs to the acylphosphatase family.

1265868:SRIM RS11540
gene id: 1265868:SRIM_RS11540
uniprot id: L8EUW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

1265868:SRIM RS30190
gene id: 1265868:SRIM_RS30190
uniprot id: A0A8A1UUG8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1265868:SRIM RS32115
gene id: 1265868:SRIM_RS32115
uniprot id: L8EHW6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1265868:SRIM RS15100
gene id: 1265868:SRIM_RS15100
uniprot id: L8EMZ6
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

1265868:SRIM RS00455
gene id: 1265868:SRIM_RS00455
uniprot id: L8F0L0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1265868:SRIM RS25670
gene id: 1265868:SRIM_RS25670
uniprot id: L8END7
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1265868:SRIM RS19085
gene id: 1265868:SRIM_RS19085
uniprot id: L8EMQ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1265868:SRIM RS08485
gene id: 1265868:SRIM_RS08485
uniprot id: A0A8A1V564
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1265868:SRIM RS30635
gene id: 1265868:SRIM_RS30635
uniprot id: A0A8A1V0G4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1265868:SRIM RS22805
gene id: 1265868:SRIM_RS22805
uniprot id: A0A8A1UPU0
names: Similarity
messages: Belongs to the DnaX/STICHEL family.

1265868:SRIM RS15375
gene id: 1265868:SRIM_RS15375
uniprot id: L8EEF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1265868:SRIM RS02505
gene id: 1265868:SRIM_RS02505
uniprot id: L8EZQ8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1265868:SRIM RS26860
gene id: 1265868:SRIM_RS26860
uniprot id: L8EQY1
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1265868:SRIM RS23295
gene id: 1265868:SRIM_RS23295
uniprot id: L8EQ88
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1265868:SRIM RS39245
gene id: 1265868:SRIM_RS39245
uniprot id: L8EW37
names: Similarity
messages: Belongs to the HupF/HypC family.

1265868:SRIM RS04005
gene id: 1265868:SRIM_RS04005
uniprot id: L8EQ39
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1265868:SRIM RS10035
gene id: 1265868:SRIM_RS10035
uniprot id: L8EEG1
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

1265868:SRIM RS29695
gene id: 1265868:SRIM_RS29695
uniprot id: L8EDM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1265868:SRIM RS28740
gene id: 1265868:SRIM_RS28740
uniprot id: L8ESB6
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS30925
gene id: 1265868:SRIM_RS30925
uniprot id: L8ET24
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS25085
gene id: 1265868:SRIM_RS25085
uniprot id: L8ES39
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1265868:SRIM RS15700
gene id: 1265868:SRIM_RS15700
uniprot id: L8EGB5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

1265868:SRIM RS09175
gene id: 1265868:SRIM_RS09175
uniprot id: L8EJI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

1265868:SRIM RS29020
gene id: 1265868:SRIM_RS29020
uniprot id: L8EQ22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS06785
gene id: 1265868:SRIM_RS06785
uniprot id: L8EK21
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS05490
gene id: 1265868:SRIM_RS05490
uniprot id: L8EGP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

1265868:SRIM RS07495
gene id: 1265868:SRIM_RS07495
uniprot id: L8EHW8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1265868:SRIM RS16615
gene id: 1265868:SRIM_RS16615
uniprot id: L8EKZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. Tam family.
messages: Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
messages: Cytoplasm

1265868:SRIM RS19415
gene id: 1265868:SRIM_RS19415
uniprot id: L8EVR7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1265868:SRIM RS35035
gene id: 1265868:SRIM_RS35035
uniprot id: L8EX99
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

1265868:SRIM RS20335
gene id: 1265868:SRIM_RS20335
uniprot id: L8EYY9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS29670
gene id: 1265868:SRIM_RS29670
uniprot id: L8EE58
names: Similarity
messages: Belongs to the acylphosphatase family.

1265868:SRIM RS31560
gene id: 1265868:SRIM_RS31560
uniprot id: A0A8A1UWD4
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.

1265868:SRIM RS18315
gene id: 1265868:SRIM_RS18315
uniprot id: L8ENF8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1265868:SRIM RS11520
gene id: 1265868:SRIM_RS11520
uniprot id: L8EDA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1265868:SRIM RS09220
gene id: 1265868:SRIM_RS09220
uniprot id: L8EJV1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1265868:SRIM RS05685
gene id: 1265868:SRIM_RS05685
uniprot id: L8ESH1
names: Similarity
messages: Belongs to the cytochrome P450 family.

1265868:SRIM RS07645
gene id: 1265868:SRIM_RS07645
uniprot id: L8ESZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1265868:SRIM RS27775
gene id: 1265868:SRIM_RS27775
uniprot id: L8EEY2
names: Similarity
messages: Belongs to the UPF0166 family.

1265868:SRIM RS14890
gene id: 1265868:SRIM_RS14890
uniprot id: A0A8A1UKI9
names: Subcellular Location Annotation
messages: Cell membrane

1265868:SRIM RS28395
gene id: 1265868:SRIM_RS28395
uniprot id: L8EUP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS34385
gene id: 1265868:SRIM_RS34385
uniprot id: L8EV21
names: Similarity
messages: Belongs to the thioesterase family.

1265868:SRIM RS10025
gene id: 1265868:SRIM_RS10025
uniprot id: L8EMH4
names: Similarity
messages: Belongs to the peptidase M1 family.

1265868:SRIM RS20530
gene id: 1265868:SRIM_RS20530
uniprot id: A0A8A1UNU6
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS15415
gene id: 1265868:SRIM_RS15415
uniprot id: L8EEA9
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS23690
gene id: 1265868:SRIM_RS23690
uniprot id: L8EQA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1265868:SRIM RS09140
gene id: 1265868:SRIM_RS09140
uniprot id: A0A8A1UN77
names: Similarity
messages: Belongs to the peptidase S8 family.

1265868:SRIM RS33550
gene id: 1265868:SRIM_RS33550
uniprot id: L8ET01
names: Similarity
messages: Belongs to the AHA1 family.

1265868:SRIM RS20005
gene id: 1265868:SRIM_RS20005
uniprot id: L8EVT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS24765
gene id: 1265868:SRIM_RS24765
uniprot id: L8EK91
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

1265868:SRIM RS13165
gene id: 1265868:SRIM_RS13165
uniprot id: L8EEX7
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

1265868:SRIM RS15280
gene id: 1265868:SRIM_RS15280
uniprot id: L8EGW0
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS04660
gene id: 1265868:SRIM_RS04660
uniprot id: A0A8A1UKW1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1265868:SRIM RS35350
gene id: 1265868:SRIM_RS35350
uniprot id: L8ELY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. L-carnitine dehydrogenase subfamily.
messages: Catalyzes the NAD(+)-dependent oxidation of L-carnitine to 3-dehydrocarnitine.
messages: Cytoplasm
messages: Homodimer.

1265868:SRIM RS21280
gene id: 1265868:SRIM_RS21280
uniprot id: L8F1B6
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

1265868:SRIM RS38985
gene id: 1265868:SRIM_RS38985
uniprot id: L8ERF7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS01800
gene id: 1265868:SRIM_RS01800
uniprot id: L8EW79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS21345
gene id: 1265868:SRIM_RS21345
uniprot id: L8F0L5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1265868:SRIM RS37140
gene id: 1265868:SRIM_RS37140
uniprot id: A0A8A1V270
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

1265868:SRIM RS12570
gene id: 1265868:SRIM_RS12570
uniprot id: L8EYC3
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS15575
gene id: 1265868:SRIM_RS15575
uniprot id: L8EKA8
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1265868:SRIM RS26010
gene id: 1265868:SRIM_RS26010
uniprot id: L8EEE7
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

1265868:SRIM RS35680
gene id: 1265868:SRIM_RS35680
uniprot id: L8EPJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS07280
gene id: 1265868:SRIM_RS07280
uniprot id: L8EQV7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1265868:SRIM RS21665
gene id: 1265868:SRIM_RS21665
uniprot id: L8F4G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1265868:SRIM RS39325
gene id: 1265868:SRIM_RS39325
uniprot id: L8EXE0
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS03520
gene id: 1265868:SRIM_RS03520
uniprot id: L8EPM0
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1265868:SRIM RS28985
gene id: 1265868:SRIM_RS28985
uniprot id: L8ETB0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS11080
gene id: 1265868:SRIM_RS11080
uniprot id: L8EML5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1265868:SRIM RS37575
gene id: 1265868:SRIM_RS37575
uniprot id: L8F0L9
names: Similarity
messages: Belongs to the peptidase C40 family.

1265868:SRIM RS10070
gene id: 1265868:SRIM_RS10070
uniprot id: L8EH37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbxX/CfxQ family.
messages: Cytoplasm

1265868:SRIM RS38330
gene id: 1265868:SRIM_RS38330
uniprot id: L8EYU3
names: Disruption Phenotype
names: Function
names: Similarity
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Cells lacking this gene are unable to produce oxytetracycline.
messages: Involved in the biosynthesis of the antibiotics tetracycline and oxytetracycline. Catalyzes the C(5) reduction of 5a,11a-dehydrooxytetracycline to yield oxytetracycline as a major product. Also catalyzes the C(12) reduction of 5a,11a-dehydrotetracycline (12-dehydrotetracycline) to produce tetracycline as a minor product.

1265868:SRIM RS36030
gene id: 1265868:SRIM_RS36030
uniprot id: L8EQI1
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS09970
gene id: 1265868:SRIM_RS09970
uniprot id: L8EMA7
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS30135
gene id: 1265868:SRIM_RS30135
uniprot id: L8EG14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1265868:SRIM RS34510
gene id: 1265868:SRIM_RS34510
uniprot id: L8ELQ1
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

1265868:SRIM RS07670
gene id: 1265868:SRIM_RS07670
uniprot id: L8ESZ3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1265868:SRIM RS35845
gene id: 1265868:SRIM_RS35845
uniprot id: L8ERI0
names: Function
messages: Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

1265868:SRIM RS30645
gene id: 1265868:SRIM_RS30645
uniprot id: L8EEA3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS27650
gene id: 1265868:SRIM_RS27650
uniprot id: L8EP81
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1265868:SRIM RS20140
gene id: 1265868:SRIM_RS20140
uniprot id: L8EHJ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1265868:SRIM RS07125
gene id: 1265868:SRIM_RS07125
uniprot id: A0A8A1UMS1
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1265868:SRIM RS26765
gene id: 1265868:SRIM_RS26765
uniprot id: A0A8A1UX05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1265868:SRIM RS08680
gene id: 1265868:SRIM_RS08680
uniprot id: A0A8A1UHR6
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS07200
gene id: 1265868:SRIM_RS07200
uniprot id: L8EPW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1265868:SRIM RS12945
gene id: 1265868:SRIM_RS12945
uniprot id: A0A8A1V310
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1265868:SRIM RS19205
gene id: 1265868:SRIM_RS19205
uniprot id: L8EPP7
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

1265868:SRIM RS38410
gene id: 1265868:SRIM_RS38410
uniprot id: A0A8A1V1W7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1265868:SRIM RS18375
gene id: 1265868:SRIM_RS18375
uniprot id: L8EJM9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1265868:SRIM RS35725
gene id: 1265868:SRIM_RS35725
uniprot id: L8ESE0
names: Similarity
messages: In the N-terminal section; belongs to the cytochrome P450 family.

1265868:SRIM RS35930
gene id: 1265868:SRIM_RS35930
uniprot id: L8ERK0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1265868:SRIM RS04935
gene id: 1265868:SRIM_RS04935
uniprot id: L8EQS6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1265868:SRIM RS20260
gene id: 1265868:SRIM_RS20260
uniprot id: L8EYX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1265868:SRIM RS29350
gene id: 1265868:SRIM_RS29350
uniprot id: L8EJ39
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1265868:SRIM RS00795
gene id: 1265868:SRIM_RS00795
uniprot id: L8EZL8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1265868:SRIM RS21005
gene id: 1265868:SRIM_RS21005
uniprot id: L8EHI3
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1265868:SRIM RS06445
gene id: 1265868:SRIM_RS06445
uniprot id: L8EGE1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1265868:SRIM RS20650
gene id: 1265868:SRIM_RS20650
uniprot id: L8EXY5
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1265868:SRIM RS09565
gene id: 1265868:SRIM_RS09565
uniprot id: L8EQA8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

1265868:SRIM RS31170
gene id: 1265868:SRIM_RS31170
uniprot id: L8EK84
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS26975
gene id: 1265868:SRIM_RS26975
uniprot id: L8ER07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS21725
gene id: 1265868:SRIM_RS21725
uniprot id: L8F1M0
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

1265868:SRIM RS26030
gene id: 1265868:SRIM_RS26030
uniprot id: A0A8A1UTN6
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS29540
gene id: 1265868:SRIM_RS29540
uniprot id: L8EJ38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1265868:SRIM RS21370
gene id: 1265868:SRIM_RS21370
uniprot id: L8F0M2
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS14770
gene id: 1265868:SRIM_RS14770
uniprot id: L8EMX2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1265868:SRIM RS08695
gene id: 1265868:SRIM_RS08695
uniprot id: L8EIE6
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

1265868:SRIM RS01030
gene id: 1265868:SRIM_RS01030
uniprot id: L8EUY3
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

1265868:SRIM RS25550
gene id: 1265868:SRIM_RS25550
uniprot id: L8EKF6
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1265868:SRIM RS32835
gene id: 1265868:SRIM_RS32835
uniprot id: L8EE77
names: Similarity
messages: Belongs to the TPP enzyme family.

1265868:SRIM RS36145
gene id: 1265868:SRIM_RS36145
uniprot id: L8EDD9
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS07490
gene id: 1265868:SRIM_RS07490
uniprot id: L8EI99
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1265868:SRIM RS25415
gene id: 1265868:SRIM_RS25415
uniprot id: L8EIL5
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1265868:SRIM RS05400
gene id: 1265868:SRIM_RS05400
uniprot id: L8EJR1
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1265868:SRIM RS10670
gene id: 1265868:SRIM_RS10670
uniprot id: A0A8A1UIM1
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1265868:SRIM RS32295
gene id: 1265868:SRIM_RS32295
uniprot id: L8EIA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1265868:SRIM RS20750
gene id: 1265868:SRIM_RS20750
uniprot id: L8EXU5
names: Similarity
messages: Belongs to the pirin family.

1265868:SRIM RS08510
gene id: 1265868:SRIM_RS08510
uniprot id: L8ENX3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1265868:SRIM RS24565
gene id: 1265868:SRIM_RS24565
uniprot id: L8ETZ8
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1265868:SRIM RS25315
gene id: 1265868:SRIM_RS25315
uniprot id: L8ENT8
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS39475
gene id: 1265868:SRIM_RS39475
uniprot id: L8EKH0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1265868:SRIM RS04015
gene id: 1265868:SRIM_RS04015
uniprot id: L8ENV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1265868:SRIM RS06705
gene id: 1265868:SRIM_RS06705
uniprot id: A0A8A1UGU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1265868:SRIM RS00405
gene id: 1265868:SRIM_RS00405
uniprot id: L8F0X6
names: Subcellular Location Annotation
messages: Cytoplasm

1265868:SRIM RS31860
gene id: 1265868:SRIM_RS31860
uniprot id: L8EUK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1265868:SRIM RS27090
gene id: 1265868:SRIM_RS27090
uniprot id: L8EMG0
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1265868:SRIM RS14970
gene id: 1265868:SRIM_RS14970
uniprot id: L8EEU8
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1265868:SRIM RS39280
gene id: 1265868:SRIM_RS39280
uniprot id: L8EWX7
names: Similarity
messages: Belongs to the HypD family.

1265868:SRIM RS08780
gene id: 1265868:SRIM_RS08780
uniprot id: L8EDG9
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

1265868:SRIM RS01215
gene id: 1265868:SRIM_RS01215
uniprot id: L8EVP6
names: Similarity
messages: Belongs to the amidinotransferase family.

1265868:SRIM RS20735
gene id: 1265868:SRIM_RS20735
uniprot id: L8F0I0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS33305
gene id: 1265868:SRIM_RS33305
uniprot id: L8EQU9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1265868:SRIM RS15270
gene id: 1265868:SRIM_RS15270
uniprot id: L8EJW6
names: Subcellular Location Annotation
messages: Cell membrane

1265868:SRIM RS01530
gene id: 1265868:SRIM_RS01530
uniprot id: L8F0B9
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS18820
gene id: 1265868:SRIM_RS18820
uniprot id: L8ETF4
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1265868:SRIM RS36010
gene id: 1265868:SRIM_RS36010
uniprot id: L8ERL6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1265868:SRIM RS25710
gene id: 1265868:SRIM_RS25710
uniprot id: L8EN29
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1265868:SRIM RS22750
gene id: 1265868:SRIM_RS22750
uniprot id: L8EK34
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

1265868:SRIM RS23550
gene id: 1265868:SRIM_RS23550
uniprot id: L8EK68
names: Similarity
messages: Belongs to the WrbA family.

1265868:SRIM RS21080
gene id: 1265868:SRIM_RS21080
uniprot id: L8EHJ8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1265868:SRIM RS20210
gene id: 1265868:SRIM_RS20210
uniprot id: L8EYW2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS30210
gene id: 1265868:SRIM_RS30210
uniprot id: L8EDP7
names: Similarity
messages: Belongs to the ribF family.

1265868:SRIM RS08885
gene id: 1265868:SRIM_RS08885
uniprot id: A0A8A1V572
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1265868:SRIM RS01025
gene id: 1265868:SRIM_RS01025
uniprot id: L8EUK0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1265868:SRIM RS05460
gene id: 1265868:SRIM_RS05460
uniprot id: L8EG41
names: Similarity
messages: Belongs to the GcvT family.

1265868:SRIM RS03185
gene id: 1265868:SRIM_RS03185
uniprot id: L8EDZ1
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS02440
gene id: 1265868:SRIM_RS02440
uniprot id: L8F2Q7
names: Similarity
messages: Belongs to the cytochrome P450 family.

1265868:SRIM RS08490
gene id: 1265868:SRIM_RS08490
uniprot id: A0A8A1UKZ3
names: Similarity
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.

1265868:SRIM RS10235
gene id: 1265868:SRIM_RS10235
uniprot id: L8EKV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1265868:SRIM RS28975
gene id: 1265868:SRIM_RS28975
uniprot id: L8EQ89
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1265868:SRIM RS00900
gene id: 1265868:SRIM_RS00900
uniprot id: L8EUN9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1265868:SRIM RS25475
gene id: 1265868:SRIM_RS25475
uniprot id: L8EGE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1265868:SRIM RS12875
gene id: 1265868:SRIM_RS12875
uniprot id: L8EZ66
names: Similarity
messages: Belongs to the CdaR family.

1265868:SRIM RS35840
gene id: 1265868:SRIM_RS35840
uniprot id: L8EVQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. EgtD family.
messages: Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine.
messages: Monomer.

1265868:SRIM RS13590
gene id: 1265868:SRIM_RS13590
uniprot id: L8EKB8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1265868:SRIM RS36050
gene id: 1265868:SRIM_RS36050
uniprot id: L8EUN2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1265868:SRIM RS06615
gene id: 1265868:SRIM_RS06615
uniprot id: L8EQP1
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS38325
gene id: 1265868:SRIM_RS38325
uniprot id: L8EUQ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PheA/TfdB FAD monooxygenase family.
messages: Binds 1 FAD per subunit.
messages: Involved in the biosynthesis of the antibiotics oxytetracycline and tetracycline. OxyS starts by catalyzing the stereospecific hydroxylation of anhydrotetracycline at C(6) position to yield 5a,11a-dehydrotetracycline (12-dehydrotetracycline). If the released product is captured by OxyR, it is reduced to tetracycline. However, if the released product is recaptured by OxyS, it performs an additional hydroxylation at C(5), producing 5a,11a-dehydrooxytetracycline, which, following the action of OxyR becomes oxytetracycline.
messages: Monomer.

1265868:SRIM RS30345
gene id: 1265868:SRIM_RS30345
uniprot id: L8EPJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1265868:SRIM RS15750
gene id: 1265868:SRIM_RS15750
uniprot id: L8ERA6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

1265868:SRIM RS15315
gene id: 1265868:SRIM_RS15315
uniprot id: L8EGJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1265868:SRIM RS19570
gene id: 1265868:SRIM_RS19570
uniprot id: A0A8A1UVJ5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1265868:SRIM RS31630
gene id: 1265868:SRIM_RS31630
uniprot id: A0A8A1UXQ4
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1265868:SRIM RS28295
gene id: 1265868:SRIM_RS28295
uniprot id: A0A8A1V5R1
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1265868:SRIM RS19175
gene id: 1265868:SRIM_RS19175
uniprot id: L8EKA9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

1265868:SRIM RS09090
gene id: 1265868:SRIM_RS09090
uniprot id: L8EHI2
names: Similarity
messages: Belongs to the peptidase U62 family.

1265868:SRIM RS24805
gene id: 1265868:SRIM_RS24805
uniprot id: L8EL53
names: Similarity
messages: Belongs to the CutC family.

1265868:SRIM RS39125
gene id: 1265868:SRIM_RS39125
uniprot id: L8EWU3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1265868:SRIM RS16745
gene id: 1265868:SRIM_RS16745
uniprot id: A0A8A1V4P7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

1265868:SRIM RS04100
gene id: 1265868:SRIM_RS04100
uniprot id: L8ET77
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

1265868:SRIM RS01320
gene id: 1265868:SRIM_RS01320
uniprot id: L8EWY6
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1265868:SRIM RS06600
gene id: 1265868:SRIM_RS06600
uniprot id: L8EPG0
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS33715
gene id: 1265868:SRIM_RS33715
uniprot id: L8ETN2
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1265868:SRIM RS12400
gene id: 1265868:SRIM_RS12400
uniprot id: A0A8A1UJF2
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS18075
gene id: 1265868:SRIM_RS18075
uniprot id: L8EU01
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1265868:SRIM RS36900
gene id: 1265868:SRIM_RS36900
uniprot id: L8EFE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

1265868:SRIM RS15435
gene id: 1265868:SRIM_RS15435
uniprot id: L8EDA7
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1265868:SRIM RS40025
gene id: 1265868:SRIM_RS40025
uniprot id: L8EWU4
names: Similarity
messages: Belongs to the cytochrome P450 family.

1265868:SRIM RS07350
gene id: 1265868:SRIM_RS07350
uniprot id: L8EKE3
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1265868:SRIM RS39885
gene id: 1265868:SRIM_RS39885
uniprot id: L8EXI9
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1265868:SRIM RS28795
gene id: 1265868:SRIM_RS28795
uniprot id: L8ES13
names: Similarity
messages: Belongs to the peptidase S8 family.

1265868:SRIM RS31590
gene id: 1265868:SRIM_RS31590
uniprot id: A0A8A1V0X1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1265868:SRIM RS03055
gene id: 1265868:SRIM_RS03055
uniprot id: L8ERP5
names: Similarity
messages: Belongs to the cytochrome P450 family.

1265868:SRIM RS09120
gene id: 1265868:SRIM_RS09120
uniprot id: L8EH48
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1265868:SRIM RS02430
gene id: 1265868:SRIM_RS02430
uniprot id: L8EZN8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1265868:SRIM RS03635
gene id: 1265868:SRIM_RS03635
uniprot id: L8EK59
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1265868:SRIM RS05995
gene id: 1265868:SRIM_RS05995
uniprot id: L8EIU4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1265868:SRIM RS28725
gene id: 1265868:SRIM_RS28725
uniprot id: L8ER33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1265868:SRIM RS26415
gene id: 1265868:SRIM_RS26415
uniprot id: L8EF75
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS24730
gene id: 1265868:SRIM_RS24730
uniprot id: A0A8A1UPV5
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1265868:SRIM RS29865
gene id: 1265868:SRIM_RS29865
uniprot id: A0A8A1UYI7
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1265868:SRIM RS29410
gene id: 1265868:SRIM_RS29410
uniprot id: L8EET3
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1265868:SRIM RS29030
gene id: 1265868:SRIM_RS29030
uniprot id: L8EP64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS06850
gene id: 1265868:SRIM_RS06850
uniprot id: A0A8A1UK36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

1265868:SRIM RS13455
gene id: 1265868:SRIM_RS13455
uniprot id: L8EWE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1265868:SRIM RS27590
gene id: 1265868:SRIM_RS27590
uniprot id: L8EMY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1265868:SRIM RS02460
gene id: 1265868:SRIM_RS02460
uniprot id: L8EYW5
names: Similarity
messages: Belongs to the cytochrome P450 family.

1265868:SRIM RS42110
gene id: 1265868:SRIM_RS42110
uniprot id: L8F158
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

1265868:SRIM RS29915
gene id: 1265868:SRIM_RS29915
uniprot id: A0A8A1UYQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1265868:SRIM RS28685
gene id: 1265868:SRIM_RS28685
uniprot id: L8ER75
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS18155
gene id: 1265868:SRIM_RS18155
uniprot id: A0A8A1V5L4
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

1265868:SRIM RS10340
gene id: 1265868:SRIM_RS10340
uniprot id: L8EKY0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1265868:SRIM RS36710
gene id: 1265868:SRIM_RS36710
uniprot id: A0A8A1V0M3
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1265868:SRIM RS18590
gene id: 1265868:SRIM_RS18590
uniprot id: L8EXN1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1265868:SRIM RS04425
gene id: 1265868:SRIM_RS04425
uniprot id: L8EHP9
names: Similarity
messages: Belongs to the cytochrome P450 family.

1265868:SRIM RS28555
gene id: 1265868:SRIM_RS28555
uniprot id: L8EQ14
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1265868:SRIM RS21300
gene id: 1265868:SRIM_RS21300
uniprot id: A0A8A1UUS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1265868:SRIM RS35095
gene id: 1265868:SRIM_RS35095
uniprot id: L8EUE5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1265868:SRIM RS06805
gene id: 1265868:SRIM_RS06805
uniprot id: L8EJ31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1265868:SRIM RS38880
gene id: 1265868:SRIM_RS38880
uniprot id: L8ESL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1265868:SRIM RS03775
gene id: 1265868:SRIM_RS03775
uniprot id: L8EGD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1265868:SRIM RS06740
gene id: 1265868:SRIM_RS06740
uniprot id: L8EQQ9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS08925
gene id: 1265868:SRIM_RS08925
uniprot id: L8EIX6
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

1265868:SRIM RS30600
gene id: 1265868:SRIM_RS30600
uniprot id: L8EFC1
names: Subcellular Location Annotation
messages: Cytoplasm

1265868:SRIM RS09660
gene id: 1265868:SRIM_RS09660
uniprot id: L8EEJ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

1265868:SRIM RS10190
gene id: 1265868:SRIM_RS10190
uniprot id: L8EL02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1265868:SRIM RS07695
gene id: 1265868:SRIM_RS07695
uniprot id: A0A8A1UQ23
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

1265868:SRIM RS35125
gene id: 1265868:SRIM_RS35125
uniprot id: L8ETY3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1265868:SRIM RS19300
gene id: 1265868:SRIM_RS19300
uniprot id: L8EUZ7
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1265868:SRIM RS29085
gene id: 1265868:SRIM_RS29085
uniprot id: A0A8A1UY47
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1265868:SRIM RS28650
gene id: 1265868:SRIM_RS28650
uniprot id: L8EPQ9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

1265868:SRIM RS10860
gene id: 1265868:SRIM_RS10860
uniprot id: L8EUX8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Belongs to the sulfur carrier protein TusA family.

1265868:SRIM RS09630
gene id: 1265868:SRIM_RS09630
uniprot id: L8EG02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1265868:SRIM RS33475
gene id: 1265868:SRIM_RS33475
uniprot id: L8ESN5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1265868:SRIM RS15360
gene id: 1265868:SRIM_RS15360
uniprot id: L8EED6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1265868:SRIM RS01445
gene id: 1265868:SRIM_RS01445
uniprot id: L8EX13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS29980
gene id: 1265868:SRIM_RS29980
uniprot id: L8EXQ8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1265868:SRIM RS16005
gene id: 1265868:SRIM_RS16005
uniprot id: L8EMT8
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

1265868:SRIM RS23795
gene id: 1265868:SRIM_RS23795
uniprot id: L8ENV1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS30350
gene id: 1265868:SRIM_RS30350
uniprot id: L8EQL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1265868:SRIM RS18580
gene id: 1265868:SRIM_RS18580
uniprot id: A0A8A1UP49
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS09425
gene id: 1265868:SRIM_RS09425
uniprot id: A0A8A1UNY9
names: Similarity
messages: Belongs to the DapA family.

1265868:SRIM RS29060
gene id: 1265868:SRIM_RS29060
uniprot id: L8ET91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1265868:SRIM RS35540
gene id: 1265868:SRIM_RS35540
uniprot id: A0A8A1UZ58
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS30340
gene id: 1265868:SRIM_RS30340
uniprot id: L8ETW2
names: Similarity
messages: Belongs to the EccD/Snm4 family.

1265868:SRIM RS14100
gene id: 1265868:SRIM_RS14100
uniprot id: L8EMX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1265868:SRIM RS14075
gene id: 1265868:SRIM_RS14075
uniprot id: L8EMQ6
names: Similarity
messages: Belongs to the FPG family.

1265868:SRIM RS28680
gene id: 1265868:SRIM_RS28680
uniprot id: L8EVC1
names: Similarity
messages: Belongs to the catalase family.

1265868:SRIM RS26545
gene id: 1265868:SRIM_RS26545
uniprot id: L8EPF2
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS16250
gene id: 1265868:SRIM_RS16250
uniprot id: L8EDZ9
names: Similarity
messages: Belongs to the DapA family.

1265868:SRIM RS21285
gene id: 1265868:SRIM_RS21285
uniprot id: L8F0C2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1265868:SRIM RS11060
gene id: 1265868:SRIM_RS11060
uniprot id: A0A8A1UM97
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1265868:SRIM RS25905
gene id: 1265868:SRIM_RS25905
uniprot id: L8EI38
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS25225
gene id: 1265868:SRIM_RS25225
uniprot id: L8ERT0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1265868:SRIM RS09695
gene id: 1265868:SRIM_RS09695
uniprot id: L8EGX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1265868:SRIM RS16000
gene id: 1265868:SRIM_RS16000
uniprot id: L8ELN8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1265868:SRIM RS03365
gene id: 1265868:SRIM_RS03365
uniprot id: L8EHP4
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS11595
gene id: 1265868:SRIM_RS11595
uniprot id: L8EU70
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1265868:SRIM RS20765
gene id: 1265868:SRIM_RS20765
uniprot id: L8EWG9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1265868:SRIM RS30530
gene id: 1265868:SRIM_RS30530
uniprot id: A0A8A1V0G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1265868:SRIM RS06700
gene id: 1265868:SRIM_RS06700
uniprot id: L8EPH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1265868:SRIM RS22770
gene id: 1265868:SRIM_RS22770
uniprot id: L8EJ53
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1265868:SRIM RS06000
gene id: 1265868:SRIM_RS06000
uniprot id: A0A8A1UGI3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1265868:SRIM RS33155
gene id: 1265868:SRIM_RS33155
uniprot id: L8EPB4
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

1265868:SRIM RS24540
gene id: 1265868:SRIM_RS24540
uniprot id: L8EU03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1265868:SRIM RS10290
gene id: 1265868:SRIM_RS10290
uniprot id: L8EJW5
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1265868:SRIM RS38465
gene id: 1265868:SRIM_RS38465
uniprot id: L8EUN6
names: Similarity
messages: Belongs to the citrate synthase family.

1265868:SRIM RS30435
gene id: 1265868:SRIM_RS30435
uniprot id: A0A8A1UX38
names: Function
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination.

1265868:SRIM RS24135
gene id: 1265868:SRIM_RS24135
uniprot id: L8ENI9
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS01385
gene id: 1265868:SRIM_RS01385
uniprot id: L8EZQ9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1265868:SRIM RS19330
gene id: 1265868:SRIM_RS19330
uniprot id: L8EZ27
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS14180
gene id: 1265868:SRIM_RS14180
uniprot id: A0A8A1UMR9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1265868:SRIM RS31205
gene id: 1265868:SRIM_RS31205
uniprot id: L8EM82
names: Similarity
messages: Belongs to the thioesterase family.

1265868:SRIM RS31050
gene id: 1265868:SRIM_RS31050
uniprot id: L8EQ10
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1265868:SRIM RS13150
gene id: 1265868:SRIM_RS13150
uniprot id: L8EHN2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1265868:SRIM RS06520
gene id: 1265868:SRIM_RS06520
uniprot id: L8EHH3
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1265868:SRIM RS05930
gene id: 1265868:SRIM_RS05930
uniprot id: L8EE91
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1265868:SRIM RS16650
gene id: 1265868:SRIM_RS16650
uniprot id: L8EK14
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

1265868:SRIM RS23980
gene id: 1265868:SRIM_RS23980
uniprot id: L8EFJ6
names: Similarity
messages: Belongs to the peptidase M1 family.

1265868:SRIM RS10385
gene id: 1265868:SRIM_RS10385
uniprot id: L8EGY7
names: Subcellular Location Annotation
messages: Cytoplasm

1265868:SRIM RS01095
gene id: 1265868:SRIM_RS01095
uniprot id: L8ETN0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

1265868:SRIM RS12995
gene id: 1265868:SRIM_RS12995
uniprot id: A0A8A1UQP1
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS26330
gene id: 1265868:SRIM_RS26330
uniprot id: L8EW51
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1265868:SRIM RS06165
gene id: 1265868:SRIM_RS06165
uniprot id: A0A8A1ULN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbxX/CfxQ family.
messages: Cytoplasm

1265868:SRIM RS09335
gene id: 1265868:SRIM_RS09335
uniprot id: L8EDZ2
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

1265868:SRIM RS38555
gene id: 1265868:SRIM_RS38555
uniprot id: L8EI45
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1265868:SRIM RS10480
gene id: 1265868:SRIM_RS10480
uniprot id: L8EF32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1265868:SRIM RS29600
gene id: 1265868:SRIM_RS29600
uniprot id: L8EIY2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1265868:SRIM RS10020
gene id: 1265868:SRIM_RS10020
uniprot id: L8ELC1
names: Similarity
messages: Belongs to the group II decarboxylase family.

1265868:SRIM RS07700
gene id: 1265868:SRIM_RS07700
uniprot id: L8EX18
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

1265868:SRIM RS08565
gene id: 1265868:SRIM_RS08565
uniprot id: L8EJP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1265868:SRIM RS13755
gene id: 1265868:SRIM_RS13755
uniprot id: L8EJ66
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS11785
gene id: 1265868:SRIM_RS11785
uniprot id: L8EVG3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1265868:SRIM RS21305
gene id: 1265868:SRIM_RS21305
uniprot id: L8F1C2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1265868:SRIM RS08865
gene id: 1265868:SRIM_RS08865
uniprot id: L8EIS1
names: Similarity
messages: Belongs to the TlyA family.

1265868:SRIM RS29645
gene id: 1265868:SRIM_RS29645
uniprot id: L8EEB5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1265868:SRIM RS26610
gene id: 1265868:SRIM_RS26610
uniprot id: L8EPM8
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1265868:SRIM RS16570
gene id: 1265868:SRIM_RS16570
uniprot id: L8ELB7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1265868:SRIM RS33505
gene id: 1265868:SRIM_RS33505
uniprot id: L8ET11
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

1265868:SRIM RS33410
gene id: 1265868:SRIM_RS33410
uniprot id: L8ERW0
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

1265868:SRIM RS30680
gene id: 1265868:SRIM_RS30680
uniprot id: A0A8A1V1C0
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

1265868:SRIM RS06215
gene id: 1265868:SRIM_RS06215
uniprot id: A0A8A1UZV1
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.

1265868:SRIM RS04530
gene id: 1265868:SRIM_RS04530
uniprot id: L8EE28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS10320
gene id: 1265868:SRIM_RS10320
uniprot id: A0A8A1UPD9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1265868:SRIM RS20285
gene id: 1265868:SRIM_RS20285
uniprot id: L8EXN5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1265868:SRIM RS10490
gene id: 1265868:SRIM_RS10490
uniprot id: L8EEY8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS31865
gene id: 1265868:SRIM_RS31865
uniprot id: L8EYN8
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS09945
gene id: 1265868:SRIM_RS09945
uniprot id: L8EMA2
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

1265868:SRIM RS31435
gene id: 1265868:SRIM_RS31435
uniprot id: A0A8A1UZX5
names: Similarity
messages: Belongs to the isochorismate synthase family.

1265868:SRIM RS18620
gene id: 1265868:SRIM_RS18620
uniprot id: L8ETK1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1265868:SRIM RS14170
gene id: 1265868:SRIM_RS14170
uniprot id: L8EUT7
names: Similarity
messages: Belongs to the peptidase M1 family.

1265868:SRIM RS13380
gene id: 1265868:SRIM_RS13380
uniprot id: L8EWD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1265868:SRIM RS06920
gene id: 1265868:SRIM_RS06920
uniprot id: L8EIQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

1265868:SRIM RS36075
gene id: 1265868:SRIM_RS36075
uniprot id: L8EQJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1265868:SRIM RS06095
gene id: 1265868:SRIM_RS06095
uniprot id: L8ED35
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1265868:SRIM RS30045
gene id: 1265868:SRIM_RS30045
uniprot id: L8EWW0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1265868:SRIM RS29570
gene id: 1265868:SRIM_RS29570
uniprot id: L8ENC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1265868:SRIM RS23190
gene id: 1265868:SRIM_RS23190
uniprot id: A0A8A1US67
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1265868:SRIM RS16455
gene id: 1265868:SRIM_RS16455
uniprot id: L8EFU1
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

1265868:SRIM RS25830
gene id: 1265868:SRIM_RS25830
uniprot id: L8EH67
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

1265868:SRIM RS10275
gene id: 1265868:SRIM_RS10275
uniprot id: L8EJY9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1265868:SRIM RS32350
gene id: 1265868:SRIM_RS32350
uniprot id: L8EHA9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1265868:SRIM RS29895
gene id: 1265868:SRIM_RS29895
uniprot id: L8F0W9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1265868:SRIM RS21200
gene id: 1265868:SRIM_RS21200
uniprot id: L8F463
names: Similarity
messages: Belongs to the UPF0749 family.

1265868:SRIM RS28345
gene id: 1265868:SRIM_RS28345
uniprot id: L8EUQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1265868:SRIM RS23520
gene id: 1265868:SRIM_RS23520
uniprot id: L8EKK5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1265868:SRIM RS33110
gene id: 1265868:SRIM_RS33110
uniprot id: L8ESL5
names: Subunit
messages: Homotetramer.

1265868:SRIM RS39785
gene id: 1265868:SRIM_RS39785
uniprot id: L8EHP1
names: Similarity
messages: Belongs to the HSP15 family.

1265868:SRIM RS20225
gene id: 1265868:SRIM_RS20225
uniprot id: L8F1H6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS16160
gene id: 1265868:SRIM_RS16160
uniprot id: L8EK19
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS06475
gene id: 1265868:SRIM_RS06475
uniprot id: L8EHN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbxX/CfxQ family.
messages: Cytoplasm

1265868:SRIM RS06890
gene id: 1265868:SRIM_RS06890
uniprot id: A0A8A1UJ04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1265868:SRIM RS38145
gene id: 1265868:SRIM_RS38145
uniprot id: A0A8A1V101
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1265868:SRIM RS34925
gene id: 1265868:SRIM_RS34925
uniprot id: L8ELC6
names: Similarity
messages: Belongs to the peptidase M1 family.

1265868:SRIM RS05690
gene id: 1265868:SRIM_RS05690
uniprot id: A0A8A1UZT3
names: Function
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate.

1265868:SRIM RS27060
gene id: 1265868:SRIM_RS27060
uniprot id: L8EI31
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1265868:SRIM RS30390
gene id: 1265868:SRIM_RS30390
uniprot id: L8ETV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1265868:SRIM RS02950
gene id: 1265868:SRIM_RS02950
uniprot id: A0A8A1UYT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1265868:SRIM RS28475
gene id: 1265868:SRIM_RS28475
uniprot id: L8EQZ7
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1265868:SRIM RS35495
gene id: 1265868:SRIM_RS35495
uniprot id: L8EEW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1265868:SRIM RS30660
gene id: 1265868:SRIM_RS30660
uniprot id: L8EL50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1265868:SRIM RS28455
gene id: 1265868:SRIM_RS28455
uniprot id: A0A8A1V0C7
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS16580
gene id: 1265868:SRIM_RS16580
uniprot id: L8EPA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1265868:SRIM RS01780
gene id: 1265868:SRIM_RS01780
uniprot id: L8F070
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1265868:SRIM RS01350
gene id: 1265868:SRIM_RS01350
uniprot id: L8EWI3
names: Similarity
messages: Belongs to the cytochrome P450 family.

1265868:SRIM RS15460
gene id: 1265868:SRIM_RS15460
uniprot id: L8EHU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1265868:SRIM RS37580
gene id: 1265868:SRIM_RS37580
uniprot id: L8EZG3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1265868:SRIM RS37340
gene id: 1265868:SRIM_RS37340
uniprot id: L8EKQ7
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS23170
gene id: 1265868:SRIM_RS23170
uniprot id: A0A8A1UX26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Membrane

1265868:SRIM RS13885
gene id: 1265868:SRIM_RS13885
uniprot id: L8EF78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1265868:SRIM RS35670
gene id: 1265868:SRIM_RS35670
uniprot id: L8EP99
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS28480
gene id: 1265868:SRIM_RS28480
uniprot id: L8EQ27
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1265868:SRIM RS25515
gene id: 1265868:SRIM_RS25515
uniprot id: L8EHF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1265868:SRIM RS11020
gene id: 1265868:SRIM_RS11020
uniprot id: L8EDL5
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1265868:SRIM RS20685
gene id: 1265868:SRIM_RS20685
uniprot id: L8F0K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1265868:SRIM RS18660
gene id: 1265868:SRIM_RS18660
uniprot id: L8ETI3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1265868:SRIM RS10830
gene id: 1265868:SRIM_RS10830
uniprot id: L8EQS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS25985
gene id: 1265868:SRIM_RS25985
uniprot id: L8EEF0
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1265868:SRIM RS20775
gene id: 1265868:SRIM_RS20775
uniprot id: L8EXU0
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1265868:SRIM RS07130
gene id: 1265868:SRIM_RS07130
uniprot id: L8EU61
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1265868:SRIM RS12955
gene id: 1265868:SRIM_RS12955
uniprot id: L8EYF7
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS20575
gene id: 1265868:SRIM_RS20575
uniprot id: L8EXS7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1265868:SRIM RS16245
gene id: 1265868:SRIM_RS16245
uniprot id: A0A8A1UPV3
names: Similarity
messages: Belongs to the proline racemase family.

1265868:SRIM RS15740
gene id: 1265868:SRIM_RS15740
uniprot id: A0A8A1UKW2
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

1265868:SRIM RS35070
gene id: 1265868:SRIM_RS35070
uniprot id: L8EUD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS24860
gene id: 1265868:SRIM_RS24860
uniprot id: A0A8A1UT12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1265868:SRIM RS18790
gene id: 1265868:SRIM_RS18790
uniprot id: L8EXJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1265868:SRIM RS09315
gene id: 1265868:SRIM_RS09315
uniprot id: A0A8A1UI11
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1265868:SRIM RS21215
gene id: 1265868:SRIM_RS21215
uniprot id: L8F1A3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1265868:SRIM RS29795
gene id: 1265868:SRIM_RS29795
uniprot id: L8EXT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

1265868:SRIM RS31480
gene id: 1265868:SRIM_RS31480
uniprot id: L8EEV3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1265868:SRIM RS32690
gene id: 1265868:SRIM_RS32690
uniprot id: L8EMT4
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1265868:SRIM RS36780
gene id: 1265868:SRIM_RS36780
uniprot id: A0A8A1UYY1
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

1265868:SRIM RS08300
gene id: 1265868:SRIM_RS08300
uniprot id: L8EI25
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS33710
gene id: 1265868:SRIM_RS33710
uniprot id: L8ETA0
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS21440
gene id: 1265868:SRIM_RS21440
uniprot id: L8F4B4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1265868:SRIM RS08345
gene id: 1265868:SRIM_RS08345
uniprot id: A0A8A1UNG3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1265868:SRIM RS24885
gene id: 1265868:SRIM_RS24885
uniprot id: A0A8A1V3W9
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. Futalosine hydrolase subfamily.
messages: Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).

1265868:SRIM RS13410
gene id: 1265868:SRIM_RS13410
uniprot id: A0A8A1UJW2
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS27050
gene id: 1265868:SRIM_RS27050
uniprot id: A0A8A1V585
names: Similarity
messages: Belongs to the UPF0162 family.

1265868:SRIM RS30865
gene id: 1265868:SRIM_RS30865
uniprot id: A0A8A1V5U4
names: Similarity
messages: Belongs to the citrate synthase family.

1265868:SRIM RS16515
gene id: 1265868:SRIM_RS16515
uniprot id: L8EJ29
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS03770
gene id: 1265868:SRIM_RS03770
uniprot id: L8EHA8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1265868:SRIM RS02685
gene id: 1265868:SRIM_RS02685
uniprot id: A0A8A1UJW6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1265868:SRIM RS02890
gene id: 1265868:SRIM_RS02890
uniprot id: L8EXG6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1265868:SRIM RS36695
gene id: 1265868:SRIM_RS36695
uniprot id: A0A8A1UV60
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

1265868:SRIM RS14110
gene id: 1265868:SRIM_RS14110
uniprot id: L8ELK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1265868:SRIM RS24305
gene id: 1265868:SRIM_RS24305
uniprot id: L8ENQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1265868:SRIM RS15495
gene id: 1265868:SRIM_RS15495
uniprot id: A0A8A1UTL7
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS22965
gene id: 1265868:SRIM_RS22965
uniprot id: L8EUA8
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1265868:SRIM RS16190
gene id: 1265868:SRIM_RS16190
uniprot id: L8EJS1
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1265868:SRIM RS40115
gene id: 1265868:SRIM_RS40115
uniprot id: L8EXM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1265868:SRIM RS35850
gene id: 1265868:SRIM_RS35850
uniprot id: L8ESB4
names: Function
names: Similarity
messages: Belongs to the EgtB family.
messages: Catalyzes the oxidative sulfurization of hercynine (N-alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

1265868:SRIM RS14080
gene id: 1265868:SRIM_RS14080
uniprot id: L8ELK3
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1265868:SRIM RS23485
gene id: 1265868:SRIM_RS23485
uniprot id: L8ENK8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1265868:SRIM RS18510
gene id: 1265868:SRIM_RS18510
uniprot id: L8EEK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

1265868:SRIM RS39260
gene id: 1265868:SRIM_RS39260
uniprot id: A0A8A1V3P5
names: Similarity
messages: Belongs to the universal stress protein A family.

1265868:SRIM RS17940
gene id: 1265868:SRIM_RS17940
uniprot id: L8ESS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1265868:SRIM RS18365
gene id: 1265868:SRIM_RS18365
uniprot id: L8EL00
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

1265868:SRIM RS26790
gene id: 1265868:SRIM_RS26790
uniprot id: L8ED49
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1265868:SRIM RS15955
gene id: 1265868:SRIM_RS15955
uniprot id: L8EGX1
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

1265868:SRIM RS19515
gene id: 1265868:SRIM_RS19515
uniprot id: L8EUW7
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

1265868:SRIM RS14570
gene id: 1265868:SRIM_RS14570
uniprot id: L8EXY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Gfo/Idh/MocA family.
messages: Homotetramer.
messages: Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).

1265868:SRIM RS02650
gene id: 1265868:SRIM_RS02650
uniprot id: L8EYZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1265868:SRIM RS19430
gene id: 1265868:SRIM_RS19430
uniprot id: L8EZ06
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1265868:SRIM RS01550
gene id: 1265868:SRIM_RS01550
uniprot id: L8EWD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1265868:SRIM RS25605
gene id: 1265868:SRIM_RS25605
uniprot id: L8EP52
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1265868:SRIM RS15585
gene id: 1265868:SRIM_RS15585
uniprot id: L8ENQ9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1265868:SRIM RS33040
gene id: 1265868:SRIM_RS33040
uniprot id: L8ENA9
names: Function
names: Similarity
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.

1265868:SRIM RS41425
gene id: 1265868:SRIM_RS41425
uniprot id: L8F0T7
names: Similarity
messages: Belongs to the ParB family.

1265868:SRIM RS03725
gene id: 1265868:SRIM_RS03725
uniprot id: L8EEM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1265868:SRIM RS40320
gene id: 1265868:SRIM_RS40320
uniprot id: L8EXC9
names: Similarity
messages: Belongs to the asparagine synthetase family.

1265868:SRIM RS28585
gene id: 1265868:SRIM_RS28585
uniprot id: A0A8A1USJ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS36650
gene id: 1265868:SRIM_RS36650
uniprot id: L8ELH0
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1265868:SRIM RS19580
gene id: 1265868:SRIM_RS19580
uniprot id: L8EUT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1265868:SRIM RS21435
gene id: 1265868:SRIM_RS21435
uniprot id: L8F0E9
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS38895
gene id: 1265868:SRIM_RS38895
uniprot id: L8EVL8
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1265868:SRIM RS04665
gene id: 1265868:SRIM_RS04665
uniprot id: L8EGZ6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1265868:SRIM RS19945
gene id: 1265868:SRIM_RS19945
uniprot id: L8EWM7
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1265868:SRIM RS31670
gene id: 1265868:SRIM_RS31670
uniprot id: L8EV75
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS28530
gene id: 1265868:SRIM_RS28530
uniprot id: L8EQ20
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1265868:SRIM RS37750
gene id: 1265868:SRIM_RS37750
uniprot id: L8F342
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1265868:SRIM RS39210
gene id: 1265868:SRIM_RS39210
uniprot id: L8EW18
names: Subcellular Location Annotation
messages: Cell membrane

1265868:SRIM RS11530
gene id: 1265868:SRIM_RS11530
uniprot id: L8EDU9
names: Similarity
messages: Belongs to the EfeM/EfeO family.

1265868:SRIM RS16475
gene id: 1265868:SRIM_RS16475
uniprot id: L8EFK5
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS23475
gene id: 1265868:SRIM_RS23475
uniprot id: L8EK52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1265868:SRIM RS29635
gene id: 1265868:SRIM_RS29635
uniprot id: L8EFD5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1265868:SRIM RS27620
gene id: 1265868:SRIM_RS27620
uniprot id: L8EP27
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS20645
gene id: 1265868:SRIM_RS20645
uniprot id: L8EXH0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1265868:SRIM RS27170
gene id: 1265868:SRIM_RS27170
uniprot id: L8EHL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1265868:SRIM RS14615
gene id: 1265868:SRIM_RS14615
uniprot id: L8EYI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1265868:SRIM RS18955
gene id: 1265868:SRIM_RS18955
uniprot id: L8ENX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1265868:SRIM RS02235
gene id: 1265868:SRIM_RS02235
uniprot id: L8EZK1
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1265868:SRIM RS13840
gene id: 1265868:SRIM_RS13840
uniprot id: A0A8A1UKN6
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1265868:SRIM RS33210
gene id: 1265868:SRIM_RS33210
uniprot id: L8EPG8
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1265868:SRIM RS16145
gene id: 1265868:SRIM_RS16145
uniprot id: L8EIN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1265868:SRIM RS02080
gene id: 1265868:SRIM_RS02080
uniprot id: L8ENV9
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

1265868:SRIM RS30570
gene id: 1265868:SRIM_RS30570
uniprot id: L8EEB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS28835
gene id: 1265868:SRIM_RS28835
uniprot id: L8ERA2
names: Similarity
messages: Belongs to the peptidase M4 family.

1265868:SRIM RS38315
gene id: 1265868:SRIM_RS38315
uniprot id: L8EW08
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

1265868:SRIM RS30230
gene id: 1265868:SRIM_RS30230
uniprot id: A0A8A1UVJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EccB family.
messages: Membrane

1265868:SRIM RS27475
gene id: 1265868:SRIM_RS27475
uniprot id: L8EH11
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1265868:SRIM RS14220
gene id: 1265868:SRIM_RS14220
uniprot id: L8EQM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1265868:SRIM RS29805
gene id: 1265868:SRIM_RS29805
uniprot id: L8EX37
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates guanosine-37 in various tRNAs.

1265868:SRIM RS23285
gene id: 1265868:SRIM_RS23285
uniprot id: L8EQD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1265868:SRIM RS03115
gene id: 1265868:SRIM_RS03115
uniprot id: A0A8A1UK45
names: Subcellular Location Annotation
messages: Cell membrane

1265868:SRIM RS38475
gene id: 1265868:SRIM_RS38475
uniprot id: L8EVW4
names: Similarity
messages: Belongs to the malate synthase family.

1265868:SRIM RS28285
gene id: 1265868:SRIM_RS28285
uniprot id: L8EXY1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1265868:SRIM RS09665
gene id: 1265868:SRIM_RS09665
uniprot id: L8EFE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

1265868:SRIM RS26945
gene id: 1265868:SRIM_RS26945
uniprot id: L8ES63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS41360
gene id: 1265868:SRIM_RS41360
uniprot id: L8EZU8
names: Subunit
messages: Homodimer.

1265868:SRIM RS02990
gene id: 1265868:SRIM_RS02990
uniprot id: L8EHE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1265868:SRIM RS03735
gene id: 1265868:SRIM_RS03735
uniprot id: L8EFG2
names: Similarity
messages: Belongs to the peptidase C40 family.

1265868:SRIM RS13685
gene id: 1265868:SRIM_RS13685
uniprot id: L8ELF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1265868:SRIM RS06650
gene id: 1265868:SRIM_RS06650
uniprot id: L8EPG6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1265868:SRIM RS13960
gene id: 1265868:SRIM_RS13960
uniprot id: L8EM63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1265868:SRIM RS15300
gene id: 1265868:SRIM_RS15300
uniprot id: L8EJX2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1265868:SRIM RS02170
gene id: 1265868:SRIM_RS02170
uniprot id: L8F2L3
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. Carboxylic acid reductase subfamily.
messages: Binds 1 phosphopantetheine covalently.
messages: Catalyzes the ATP- and NADPH-dependent reduction of carboxylic acids to the corresponding aldehydes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain likely catalyzes substrate activation by formation of an initial acyl-AMP intermediate, the central region contains the phosphopantetheine attachment site, and the C-terminal domain catalyzes the reduction by NADPH of the intermediate thioester formed from the attack of the phosphopantetheine thiol at the carbonyl carbon of acyl-AMP.

1265868:SRIM RS36750
gene id: 1265868:SRIM_RS36750
uniprot id: L8EKL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

1265868:SRIM RS11315
gene id: 1265868:SRIM_RS11315
uniprot id: L8EPC8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1265868:SRIM RS38900
gene id: 1265868:SRIM_RS38900
uniprot id: L8ERH7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1265868:SRIM RS04585
gene id: 1265868:SRIM_RS04585
uniprot id: A0A8A1UHS2
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS15850
gene id: 1265868:SRIM_RS15850
uniprot id: L8EVG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1265868:SRIM RS39275
gene id: 1265868:SRIM_RS39275
uniprot id: L8EXD2
names: Similarity
messages: Belongs to the HypE family.

1265868:SRIM RS23490
gene id: 1265868:SRIM_RS23490
uniprot id: L8EJB5
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1265868:SRIM RS18760
gene id: 1265868:SRIM_RS18760
uniprot id: L8ETG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1265868:SRIM RS25280
gene id: 1265868:SRIM_RS25280
uniprot id: A0A8A1URX8
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS23415
gene id: 1265868:SRIM_RS23415
uniprot id: L8EJA1
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

1265868:SRIM RS35195
gene id: 1265868:SRIM_RS35195
uniprot id: L8EUG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS14545
gene id: 1265868:SRIM_RS14545
uniprot id: L8EXX8
names: Similarity
messages: Belongs to the TPP enzyme family.

1265868:SRIM RS01910
gene id: 1265868:SRIM_RS01910
uniprot id: L8EMH2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1265868:SRIM RS36735
gene id: 1265868:SRIM_RS36735
uniprot id: A0A8A1V0A7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1265868:SRIM RS39570
gene id: 1265868:SRIM_RS39570
uniprot id: L8EKM3
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

1265868:SRIM RS25510
gene id: 1265868:SRIM_RS25510
uniprot id: L8EH24
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS08275
gene id: 1265868:SRIM_RS08275
uniprot id: L8EI22
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1265868:SRIM RS14790
gene id: 1265868:SRIM_RS14790
uniprot id: L8ES88
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1265868:SRIM RS18800
gene id: 1265868:SRIM_RS18800
uniprot id: L8EU84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1265868:SRIM RS13520
gene id: 1265868:SRIM_RS13520
uniprot id: L8EVN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1265868:SRIM RS36140
gene id: 1265868:SRIM_RS36140
uniprot id: L8EE55
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

1265868:SRIM RS00485
gene id: 1265868:SRIM_RS00485
uniprot id: L8F0K7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1265868:SRIM RS24280
gene id: 1265868:SRIM_RS24280
uniprot id: L8ENR3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1265868:SRIM RS05310
gene id: 1265868:SRIM_RS05310
uniprot id: L8EMQ5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1265868:SRIM RS22285
gene id: 1265868:SRIM_RS22285
uniprot id: L8EIG5
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS32970
gene id: 1265868:SRIM_RS32970
uniprot id: L8EPK6
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS10205
gene id: 1265868:SRIM_RS10205
uniprot id: L8EKU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1265868:SRIM RS32125
gene id: 1265868:SRIM_RS32125
uniprot id: L8EGI8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1265868:SRIM RS28880
gene id: 1265868:SRIM_RS28880
uniprot id: A0A8A1V618
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1265868:SRIM RS19495
gene id: 1265868:SRIM_RS19495
uniprot id: L8EVP8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS21545
gene id: 1265868:SRIM_RS21545
uniprot id: L8F0Q8
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS27145
gene id: 1265868:SRIM_RS27145
uniprot id: L8EHL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1265868:SRIM RS14175
gene id: 1265868:SRIM_RS14175
uniprot id: L8EQI8
names: Similarity
messages: Belongs to the allantoicase family.

1265868:SRIM RS12580
gene id: 1265868:SRIM_RS12580
uniprot id: A0A8A1ULP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS14355
gene id: 1265868:SRIM_RS14355
uniprot id: L8EDV6
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1265868:SRIM RS30065
gene id: 1265868:SRIM_RS30065
uniprot id: L8EXP6
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1265868:SRIM RS31485
gene id: 1265868:SRIM_RS31485
uniprot id: L8EFP4
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Reversible hydration of carbon dioxide.

1265868:SRIM RS04380
gene id: 1265868:SRIM_RS04380
uniprot id: L8EIK2
names: Similarity
messages: Belongs to the IMPACT family.

1265868:SRIM RS27460
gene id: 1265868:SRIM_RS27460
uniprot id: L8EE95
names: Similarity
messages: Belongs to the Fur family.

1265868:SRIM RS38620
gene id: 1265868:SRIM_RS38620
uniprot id: A0A8A1V3Y2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1265868:SRIM RS13350
gene id: 1265868:SRIM_RS13350
uniprot id: L8EWR3
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS10820
gene id: 1265868:SRIM_RS10820
uniprot id: A0A8A1UP34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

1265868:SRIM RS03270
gene id: 1265868:SRIM_RS03270
uniprot id: L8EIR1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS21330
gene id: 1265868:SRIM_RS21330
uniprot id: A0A8A1UPV8
names: Similarity
messages: Belongs to the ParB family.

1265868:SRIM RS36170
gene id: 1265868:SRIM_RS36170
uniprot id: L8ESM0
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1265868:SRIM RS26350
gene id: 1265868:SRIM_RS26350
uniprot id: L8ES02
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

1265868:SRIM RS33770
gene id: 1265868:SRIM_RS33770
uniprot id: L8ESF7
names: Similarity
messages: Belongs to the cytochrome P450 family.

1265868:SRIM RS03825
gene id: 1265868:SRIM_RS03825
uniprot id: L8EGE8
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS35405
gene id: 1265868:SRIM_RS35405
uniprot id: L8ERD7
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1265868:SRIM RS03685
gene id: 1265868:SRIM_RS03685
uniprot id: L8EFF3
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: May form a heterohexamer of 3 UreC (alpha) and 3 UreAB (gamma/beta) subunits. May also form a heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1265868:SRIM RS20720
gene id: 1265868:SRIM_RS20720
uniprot id: L8EXE2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

1265868:SRIM RS06925
gene id: 1265868:SRIM_RS06925
uniprot id: L8EN34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1265868:SRIM RS10845
gene id: 1265868:SRIM_RS10845
uniprot id: L8ERL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

1265868:SRIM RS18930
gene id: 1265868:SRIM_RS18930
uniprot id: L8EJB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1265868:SRIM RS41865
gene id: 1265868:SRIM_RS41865
uniprot id: L8F118
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1265868:SRIM RS34230
gene id: 1265868:SRIM_RS34230
uniprot id: A0A8A1UWK0
names: Similarity
messages: Belongs to the TPP enzyme family.

1265868:SRIM RS18425
gene id: 1265868:SRIM_RS18425
uniprot id: L8EJN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1265868:SRIM RS22890
gene id: 1265868:SRIM_RS22890
uniprot id: L8EER3
names: Similarity
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

1265868:SRIM RS30100
gene id: 1265868:SRIM_RS30100
uniprot id: A0A8A1UZ86
names: Similarity
messages: Belongs to the CdaR family.

1265868:SRIM RS07720
gene id: 1265868:SRIM_RS07720
uniprot id: L8ESY5
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1265868:SRIM RS13515
gene id: 1265868:SRIM_RS13515
uniprot id: L8EZL6
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS16080
gene id: 1265868:SRIM_RS16080
uniprot id: L8EMV2
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1265868:SRIM RS21585
gene id: 1265868:SRIM_RS21585
uniprot id: L8F0H6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1265868:SRIM RS41005
gene id: 1265868:SRIM_RS41005
uniprot id: L8ER44
names: Similarity
messages: Belongs to the peptidase M28 family. M28A subfamily.

1265868:SRIM RS15580
gene id: 1265868:SRIM_RS15580
uniprot id: L8EJD4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS21355
gene id: 1265868:SRIM_RS21355
uniprot id: L8F1D2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1265868:SRIM RS19195
gene id: 1265868:SRIM_RS19195
uniprot id: L8ELC7
names: Subcellular Location Annotation
messages: Cytoplasm

1265868:SRIM RS39575
gene id: 1265868:SRIM_RS39575
uniprot id: L8ELR1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1265868:SRIM RS16665
gene id: 1265868:SRIM_RS16665
uniprot id: A0A8A1UU41
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS16045
gene id: 1265868:SRIM_RS16045
uniprot id: L8EQY2
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1265868:SRIM RS19270
gene id: 1265868:SRIM_RS19270
uniprot id: L8EFJ1
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS24450
gene id: 1265868:SRIM_RS24450
uniprot id: L8EUV8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1265868:SRIM RS01470
gene id: 1265868:SRIM_RS01470
uniprot id: L8EX17
names: Subcellular Location Annotation
messages: Cell membrane

1265868:SRIM RS00825
gene id: 1265868:SRIM_RS00825
uniprot id: L8F3C4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1265868:SRIM RS33035
gene id: 1265868:SRIM_RS33035
uniprot id: L8ESN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

1265868:SRIM RS21670
gene id: 1265868:SRIM_RS21670
uniprot id: L8F0T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1265868:SRIM RS05005
gene id: 1265868:SRIM_RS05005
uniprot id: A0A8A1UNQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS14015
gene id: 1265868:SRIM_RS14015
uniprot id: A0A8A1V4J3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1265868:SRIM RS27780
gene id: 1265868:SRIM_RS27780
uniprot id: L8EF67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1265868:SRIM RS10430
gene id: 1265868:SRIM_RS10430
uniprot id: L8EHZ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1265868:SRIM RS18585
gene id: 1265868:SRIM_RS18585
uniprot id: L8ETJ6
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1265868:SRIM RS31260
gene id: 1265868:SRIM_RS31260
uniprot id: L8EH59
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1265868:SRIM RS08640
gene id: 1265868:SRIM_RS08640
uniprot id: L8EEG2
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

1265868:SRIM RS30385
gene id: 1265868:SRIM_RS30385
uniprot id: L8EPT2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1265868:SRIM RS16600
gene id: 1265868:SRIM_RS16600
uniprot id: L8EK26
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS27300
gene id: 1265868:SRIM_RS27300
uniprot id: A0A8A1UZ01
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS29330
gene id: 1265868:SRIM_RS29330
uniprot id: L8EHU2
names: Similarity
messages: Belongs to the agmatine deiminase family.

1265868:SRIM RS24660
gene id: 1265868:SRIM_RS24660
uniprot id: L8EUT2
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

1265868:SRIM RS28255
gene id: 1265868:SRIM_RS28255
uniprot id: L8ETW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1265868:SRIM RS08010
gene id: 1265868:SRIM_RS08010
uniprot id: L8ES78
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1265868:SRIM RS32590
gene id: 1265868:SRIM_RS32590
uniprot id: L8ELZ3
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

1265868:SRIM RS18685
gene id: 1265868:SRIM_RS18685
uniprot id: L8ETH9
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1265868:SRIM RS30575
gene id: 1265868:SRIM_RS30575
uniprot id: L8EFB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS09765
gene id: 1265868:SRIM_RS09765
uniprot id: L8EMR3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1265868:SRIM RS06005
gene id: 1265868:SRIM_RS06005
uniprot id: A0A8A1UIL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS05395
gene id: 1265868:SRIM_RS05395
uniprot id: L8EFH3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1265868:SRIM RS23145
gene id: 1265868:SRIM_RS23145
uniprot id: L8ET08
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS13535
gene id: 1265868:SRIM_RS13535
uniprot id: A0A8A1UZG4
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1265868:SRIM RS19335
gene id: 1265868:SRIM_RS19335
uniprot id: L8EV01
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS35590
gene id: 1265868:SRIM_RS35590
uniprot id: A0A8A1V0U0
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1265868:SRIM RS26895
gene id: 1265868:SRIM_RS26895
uniprot id: L8ES68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS28560
gene id: 1265868:SRIM_RS28560
uniprot id: L8EU40
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

1265868:SRIM RS40965
gene id: 1265868:SRIM_RS40965
uniprot id: A0A8A1V3I5
names: Similarity
messages: Belongs to the peptidase M1 family.

1265868:SRIM RS16085
gene id: 1265868:SRIM_RS16085
uniprot id: L8EMP3
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1265868:SRIM RS09675
gene id: 1265868:SRIM_RS09675
uniprot id: L8EIJ4
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1265868:SRIM RS34710
gene id: 1265868:SRIM_RS34710
uniprot id: L8EH91
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1265868:SRIM RS28575
gene id: 1265868:SRIM_RS28575
uniprot id: L8EQX7
names: Subcellular Location Annotation
messages: Cell membrane

1265868:SRIM RS06895
gene id: 1265868:SRIM_RS06895
uniprot id: L8EIQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1265868:SRIM RS26900
gene id: 1265868:SRIM_RS26900
uniprot id: L8ER21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS33755
gene id: 1265868:SRIM_RS33755
uniprot id: L8ESE2
names: Similarity
messages: Belongs to the peptidase S66 family.

1265868:SRIM RS06855
gene id: 1265868:SRIM_RS06855
uniprot id: L8EJ22
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1265868:SRIM RS02135
gene id: 1265868:SRIM_RS02135
uniprot id: L8EJH6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1265868:SRIM RS21320
gene id: 1265868:SRIM_RS21320
uniprot id: L8F0K9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1265868:SRIM RS08575
gene id: 1265868:SRIM_RS08575
uniprot id: L8EKK9
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS33365
gene id: 1265868:SRIM_RS33365
uniprot id: L8ETZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS33060
gene id: 1265868:SRIM_RS33060
uniprot id: L8ESM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan.
messages: Belongs to the glycosyl hydrolase 46 family.
messages: Secreted

1265868:SRIM RS29860
gene id: 1265868:SRIM_RS29860
uniprot id: L8EX29
names: Similarity
messages: Belongs to the DprA/Smf family.

1265868:SRIM RS12290
gene id: 1265868:SRIM_RS12290
uniprot id: L8EQ08
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1265868:SRIM RS06525
gene id: 1265868:SRIM_RS06525
uniprot id: L8EDV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

1265868:SRIM RS17910
gene id: 1265868:SRIM_RS17910
uniprot id: A0A8A1UMJ7
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS29325
gene id: 1265868:SRIM_RS29325
uniprot id: L8EJ42
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1265868:SRIM RS14145
gene id: 1265868:SRIM_RS14145
uniprot id: L8EUU5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS29595
gene id: 1265868:SRIM_RS29595
uniprot id: L8ENB4
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

1265868:SRIM RS15010
gene id: 1265868:SRIM_RS15010
uniprot id: L8EHU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS08085
gene id: 1265868:SRIM_RS08085
uniprot id: L8ERB4
names: Subcellular Location Annotation
messages: Cell membrane

1265868:SRIM RS10355
gene id: 1265868:SRIM_RS10355
uniprot id: L8EK08
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1265868:SRIM RS08280
gene id: 1265868:SRIM_RS08280
uniprot id: L8EJC3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1265868:SRIM RS40210
gene id: 1265868:SRIM_RS40210
uniprot id: A0A8A1V4K0
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

1265868:SRIM RS09740
gene id: 1265868:SRIM_RS09740
uniprot id: A0A8A1UKI4
names: Function
names: Subcellular Location Annotation
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

1265868:SRIM RS40955
gene id: 1265868:SRIM_RS40955
uniprot id: A0A8A1V191
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1265868:SRIM RS28335
gene id: 1265868:SRIM_RS28335
uniprot id: L8EXX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1265868:SRIM RS21270
gene id: 1265868:SRIM_RS21270
uniprot id: L8F0J8
names: Similarity
messages: Belongs to the UPF0232 family.

1265868:SRIM RS15865
gene id: 1265868:SRIM_RS15865
uniprot id: L8ES38
names: Subcellular Location Annotation
messages: Cell membrane

1265868:SRIM RS31105
gene id: 1265868:SRIM_RS31105
uniprot id: L8ER55
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS18380
gene id: 1265868:SRIM_RS18380
uniprot id: A0A8A1USS2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1265868:SRIM RS26575
gene id: 1265868:SRIM_RS26575
uniprot id: L8EQH4
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS09570
gene id: 1265868:SRIM_RS09570
uniprot id: L8EKX1
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1265868:SRIM RS03675
gene id: 1265868:SRIM_RS03675
uniprot id: A0A8A1UL27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1265868:SRIM RS16795
gene id: 1265868:SRIM_RS16795
uniprot id: L8EYP3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1265868:SRIM RS02640
gene id: 1265868:SRIM_RS02640
uniprot id: L8F0A3
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

1265868:SRIM RS08570
gene id: 1265868:SRIM_RS08570
uniprot id: L8EKZ1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1265868:SRIM RS00560
gene id: 1265868:SRIM_RS00560
uniprot id: A0A8A1UIV8
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

1265868:SRIM RS32150
gene id: 1265868:SRIM_RS32150
uniprot id: L8EGJ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS21340
gene id: 1265868:SRIM_RS21340
uniprot id: L8F492
names: Similarity
messages: Belongs to the thioredoxin family.

1265868:SRIM RS01765
gene id: 1265868:SRIM_RS01765
uniprot id: L8EX21
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1265868:SRIM RS33965
gene id: 1265868:SRIM_RS33965
uniprot id: A0A8A1UXE6
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS01285
gene id: 1265868:SRIM_RS01285
uniprot id: L8EZP1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1265868:SRIM RS38810
gene id: 1265868:SRIM_RS38810
uniprot id: L8EWN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1265868:SRIM RS39940
gene id: 1265868:SRIM_RS39940
uniprot id: L8EWP6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1265868:SRIM RS06505
gene id: 1265868:SRIM_RS06505
uniprot id: A0A8A1UJW8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1265868:SRIM RS18640
gene id: 1265868:SRIM_RS18640
uniprot id: L8EXM1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1265868:SRIM RS28715
gene id: 1265868:SRIM_RS28715
uniprot id: L8ESB3
names: Similarity
messages: Belongs to the peptidase S1 family.

1265868:SRIM RS06730
gene id: 1265868:SRIM_RS06730
uniprot id: L8ETU4
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1265868:SRIM RS25470
gene id: 1265868:SRIM_RS25470
uniprot id: L8EFC3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1265868:SRIM RS42295
gene id: 1265868:SRIM_RS42295
uniprot id: L8ENA8
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS32505
gene id: 1265868:SRIM_RS32505
uniprot id: A0A8A1V2R2
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS18455
gene id: 1265868:SRIM_RS18455
uniprot id: L8EDC1
names: Subcellular Location Annotation
messages: Cell membrane

1265868:SRIM RS14305
gene id: 1265868:SRIM_RS14305
uniprot id: L8EQG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1265868:SRIM RS13895
gene id: 1265868:SRIM_RS13895
uniprot id: L8EI13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1265868:SRIM RS11645
gene id: 1265868:SRIM_RS11645
uniprot id: L8EVD6
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1265868:SRIM RS39055
gene id: 1265868:SRIM_RS39055
uniprot id: L8EH41
names: Similarity
messages: Belongs to the cytochrome P450 family.

1265868:SRIM RS09305
gene id: 1265868:SRIM_RS09305
uniprot id: L8EEC3
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS38480
gene id: 1265868:SRIM_RS38480
uniprot id: L8EUN8
names: Cofactor
messages: Can also use Mn(2+) ion.

1265868:SRIM RS35935
gene id: 1265868:SRIM_RS35935
uniprot id: L8ER96
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1265868:SRIM RS07500
gene id: 1265868:SRIM_RS07500
uniprot id: L8EGX5
names: Subcellular Location Annotation
messages: Cell membrane

1265868:SRIM RS28290
gene id: 1265868:SRIM_RS28290
uniprot id: L8ETY4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1265868:SRIM RS13070
gene id: 1265868:SRIM_RS13070
uniprot id: L8EM52
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS16575
gene id: 1265868:SRIM_RS16575
uniprot id: L8EK31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1265868:SRIM RS26835
gene id: 1265868:SRIM_RS26835
uniprot id: L8EQY4
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS22950
gene id: 1265868:SRIM_RS22950
uniprot id: L8EX78
names: Similarity
messages: Belongs to the cytochrome P450 family.

1265868:SRIM RS28645
gene id: 1265868:SRIM_RS28645
uniprot id: L8EU26
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1265868:SRIM RS25180
gene id: 1265868:SRIM_RS25180
uniprot id: L8EE02
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1265868:SRIM RS25880
gene id: 1265868:SRIM_RS25880
uniprot id: L8EI33
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.
messages: Decarboxylates branched-chain and aromatic alpha-keto acids to aldehydes.

1265868:SRIM RS10530
gene id: 1265868:SRIM_RS10530
uniprot id: L8EN01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1265868:SRIM RS36770
gene id: 1265868:SRIM_RS36770
uniprot id: L8EKM0
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS22830
gene id: 1265868:SRIM_RS22830
uniprot id: L8EJ43
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS34350
gene id: 1265868:SRIM_RS34350
uniprot id: A0A8A1V0G6
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS18395
gene id: 1265868:SRIM_RS18395
uniprot id: L8EKM4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1265868:SRIM RS16450
gene id: 1265868:SRIM_RS16450
uniprot id: L8EFK9
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

1265868:SRIM RS14620
gene id: 1265868:SRIM_RS14620
uniprot id: L8EXZ1
names: Similarity
messages: Belongs to the citrate synthase family.

1265868:SRIM RS30235
gene id: 1265868:SRIM_RS30235
uniprot id: A0A8A1UVP7
names: Similarity
messages: Belongs to the WXG100 family.

1265868:SRIM RS31420
gene id: 1265868:SRIM_RS31420
uniprot id: A0A8A1UXK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Fes family.
messages: Cytoplasm

1265868:SRIM RS26155
gene id: 1265868:SRIM_RS26155
uniprot id: L8EW16
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1265868:SRIM RS12215
gene id: 1265868:SRIM_RS12215
uniprot id: L8EPZ3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1265868:SRIM RS02405
gene id: 1265868:SRIM_RS02405
uniprot id: L8F2Q2
names: Similarity
messages: Belongs to the bacterial phospholipase C family.

1265868:SRIM RS16890
gene id: 1265868:SRIM_RS16890
uniprot id: A0A8A1UM36
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1265868:SRIM RS29590
gene id: 1265868:SRIM_RS29590
uniprot id: L8EJ28
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1265868:SRIM RS28895
gene id: 1265868:SRIM_RS28895
uniprot id: L8EQA6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1265868:SRIM RS39855
gene id: 1265868:SRIM_RS39855
uniprot id: L8EWR2
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS34945
gene id: 1265868:SRIM_RS34945
uniprot id: A0A8A1UUD7
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

1265868:SRIM RS04125
gene id: 1265868:SRIM_RS04125
uniprot id: L8ET80
names: Similarity
messages: Belongs to the universal stress protein A family.

1265868:SRIM RS16265
gene id: 1265868:SRIM_RS16265
uniprot id: L8EED0
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1265868:SRIM RS28445
gene id: 1265868:SRIM_RS28445
uniprot id: A0A8A1UUT4
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS36620
gene id: 1265868:SRIM_RS36620
uniprot id: L8ED80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1265868:SRIM RS21420
gene id: 1265868:SRIM_RS21420
uniprot id: L8F0N3
names: Similarity
messages: Belongs to the FemABX family.

1265868:SRIM RS28035
gene id: 1265868:SRIM_RS28035
uniprot id: L8EM72
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

1265868:SRIM RS02390
gene id: 1265868:SRIM_RS02390
uniprot id: L8F064
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1265868:SRIM RS19250
gene id: 1265868:SRIM_RS19250
uniprot id: L8EGP1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

1265868:SRIM RS12220
gene id: 1265868:SRIM_RS12220
uniprot id: L8EPS3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1265868:SRIM RS35310
gene id: 1265868:SRIM_RS35310
uniprot id: L8EM53
names: Similarity
messages: Belongs to the cytochrome P450 family.

1265868:SRIM RS18680
gene id: 1265868:SRIM_RS18680
uniprot id: L8EUQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1265868:SRIM RS24150
gene id: 1265868:SRIM_RS24150
uniprot id: A0A8A1UW65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1265868:SRIM RS23615
gene id: 1265868:SRIM_RS23615
uniprot id: A0A8A1UQ69
names: Similarity
messages: Belongs to the peptidase S13 family.

1265868:SRIM RS01545
gene id: 1265868:SRIM_RS01545
uniprot id: A0A8A1UJD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1265868:SRIM RS28485
gene id: 1265868:SRIM_RS28485
uniprot id: L8EU56
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1265868:SRIM RS29050
gene id: 1265868:SRIM_RS29050
uniprot id: L8EQ75
names: Similarity
messages: Belongs to the peptidase M1 family.

1265868:SRIM RS34435
gene id: 1265868:SRIM_RS34435
uniprot id: L8EV12
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS35245
gene id: 1265868:SRIM_RS35245
uniprot id: L8EFE4
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1265868:SRIM RS08550
gene id: 1265868:SRIM_RS08550
uniprot id: A0A8A1UXD3
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

1265868:SRIM RS10450
gene id: 1265868:SRIM_RS10450
uniprot id: L8EFS3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1265868:SRIM RS23500
gene id: 1265868:SRIM_RS23500
uniprot id: L8EK56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1265868:SRIM RS15965
gene id: 1265868:SRIM_RS15965
uniprot id: L8EK94
names: Similarity
messages: Belongs to the UPF0434 family.

1265868:SRIM RS17295
gene id: 1265868:SRIM_RS17295
uniprot id: L8EXX2
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Reversible hydration of carbon dioxide.

1265868:SRIM RS18635
gene id: 1265868:SRIM_RS18635
uniprot id: L8ETI9
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1265868:SRIM RS40990
gene id: 1265868:SRIM_RS40990
uniprot id: A0A8A1V6E3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

1265868:SRIM RS08930
gene id: 1265868:SRIM_RS08930
uniprot id: L8EK54
names: Similarity
messages: Belongs to the IucA/IucC family.

1265868:SRIM RS09635
gene id: 1265868:SRIM_RS09635
uniprot id: L8EGE6
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS07775
gene id: 1265868:SRIM_RS07775
uniprot id: L8EX05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1265868:SRIM RS16835
gene id: 1265868:SRIM_RS16835
uniprot id: L8EYR7
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1265868:SRIM RS14765
gene id: 1265868:SRIM_RS14765
uniprot id: L8ES90
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1265868:SRIM RS22570
gene id: 1265868:SRIM_RS22570
uniprot id: L8EMQ2
names: Similarity
messages: Belongs to the Fur family.

1265868:SRIM RS26615
gene id: 1265868:SRIM_RS26615
uniprot id: L8ETQ7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS19125
gene id: 1265868:SRIM_RS19125
uniprot id: L8ELB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1265868:SRIM RS03315
gene id: 1265868:SRIM_RS03315
uniprot id: L8EJ89
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS24445
gene id: 1265868:SRIM_RS24445
uniprot id: A0A8A1USM3
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1265868:SRIM RS26705
gene id: 1265868:SRIM_RS26705
uniprot id: L8EQK7
names: Similarity
messages: Belongs to the catalase family.

1265868:SRIM RS30560
gene id: 1265868:SRIM_RS30560
uniprot id: L8EN31
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

1265868:SRIM RS21820
gene id: 1265868:SRIM_RS21820
uniprot id: L8F0X8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1265868:SRIM RS35515
gene id: 1265868:SRIM_RS35515
uniprot id: L8EIX5
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1265868:SRIM RS04285
gene id: 1265868:SRIM_RS04285
uniprot id: L8EHN0
names: Similarity
messages: Belongs to the EPSP synthase family.

1265868:SRIM RS14420
gene id: 1265868:SRIM_RS14420
uniprot id: L8EXV9
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1265868:SRIM RS28850
gene id: 1265868:SRIM_RS28850
uniprot id: L8EG45
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1265868:SRIM RS29160
gene id: 1265868:SRIM_RS29160
uniprot id: L8EID9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1265868:SRIM RS36940
gene id: 1265868:SRIM_RS36940
uniprot id: A0A8A1V394
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1265868:SRIM RS31595
gene id: 1265868:SRIM_RS31595
uniprot id: A0A8A1UT01
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS13145
gene id: 1265868:SRIM_RS13145
uniprot id: L8EDZ8
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1265868:SRIM RS35395
gene id: 1265868:SRIM_RS35395
uniprot id: L8EN14
names: Similarity
messages: Belongs to the XFP family.

1265868:SRIM RS09210
gene id: 1265868:SRIM_RS09210
uniprot id: L8EMT7
names: Similarity
messages: Belongs to the asp23 family.

1265868:SRIM RS24825
gene id: 1265868:SRIM_RS24825
uniprot id: L8EK28
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

1265868:SRIM RS28640
gene id: 1265868:SRIM_RS28640
uniprot id: L8EQ01
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

1265868:SRIM RS28270
gene id: 1265868:SRIM_RS28270
uniprot id: L8EUR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1265868:SRIM RS23165
gene id: 1265868:SRIM_RS23165
uniprot id: L8EU66
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS08465
gene id: 1265868:SRIM_RS08465
uniprot id: A0A8A1V469
names: Similarity
messages: Belongs to the IucA/IucC family.

1265868:SRIM RS28280
gene id: 1265868:SRIM_RS28280
uniprot id: L8ETV8
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1265868:SRIM RS21265
gene id: 1265868:SRIM_RS21265
uniprot id: A0A8A1UQ91
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1265868:SRIM RS29360
gene id: 1265868:SRIM_RS29360
uniprot id: L8EM29
names: Similarity
messages: Belongs to the polysaccharide lyase 8 family.

1265868:SRIM RS15330
gene id: 1265868:SRIM_RS15330
uniprot id: L8EFQ3
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS36690
gene id: 1265868:SRIM_RS36690
uniprot id: L8EL89
names: Subunit
messages: Homodimer.

1265868:SRIM RS07275
gene id: 1265868:SRIM_RS07275
uniprot id: L8ER32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1265868:SRIM RS02800
gene id: 1265868:SRIM_RS02800
uniprot id: L8EU36
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1265868:SRIM RS18950
gene id: 1265868:SRIM_RS18950
uniprot id: A0A8A1UT32
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1265868:SRIM RS24520
gene id: 1265868:SRIM_RS24520
uniprot id: L8EU38
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1265868:SRIM RS16770
gene id: 1265868:SRIM_RS16770
uniprot id: L8EYP7
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS26060
gene id: 1265868:SRIM_RS26060
uniprot id: L8EGW7
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS36575
gene id: 1265868:SRIM_RS36575
uniprot id: L8EUF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Vgb family.
messages: Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid.
messages: Monomer.

1265868:SRIM RS14795
gene id: 1265868:SRIM_RS14795
uniprot id: L8EMW8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1265868:SRIM RS13880
gene id: 1265868:SRIM_RS13880
uniprot id: L8EEZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1265868:SRIM RS26630
gene id: 1265868:SRIM_RS26630
uniprot id: A0A8A1UTR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1265868:SRIM RS28160
gene id: 1265868:SRIM_RS28160
uniprot id: A0A8A1UUN4
names: Similarity
messages: Belongs to the cytochrome P450 family.

1265868:SRIM RS30700
gene id: 1265868:SRIM_RS30700
uniprot id: A0A8A1USK7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1265868:SRIM RS24670
gene id: 1265868:SRIM_RS24670
uniprot id: L8ETY1
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1265868:SRIM RS25410
gene id: 1265868:SRIM_RS25410
uniprot id: L8EJ30
names: Similarity
messages: Belongs to the peptidase C40 family.

1265868:SRIM RS08250
gene id: 1265868:SRIM_RS08250
uniprot id: A0A8A1V2N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urea transporter family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS18310
gene id: 1265868:SRIM_RS18310
uniprot id: A0A8A1V1Z1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1265868:SRIM RS13720
gene id: 1265868:SRIM_RS13720
uniprot id: L8EI87
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1265868:SRIM RS07325
gene id: 1265868:SRIM_RS07325
uniprot id: L8ER43
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An FAD-requiring monooxygenase active on some tetracycline antibiotic derivatives, which leads to their inactivation. Hydroxylates carbon 11a of tetracycline and some analogs.
messages: Belongs to the aromatic-ring hydroxylase family. TetX subfamily.
messages: Consists of an N-terminal FAD-binding domain with a Rossman fold and a C-terminal substrate-binding domain.
messages: Cytoplasm
messages: Monomer.

1265868:SRIM RS17145
gene id: 1265868:SRIM_RS17145
uniprot id: L8EZ97
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1265868:SRIM RS14710
gene id: 1265868:SRIM_RS14710
uniprot id: L8EXB6
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1265868:SRIM RS12440
gene id: 1265868:SRIM_RS12440
uniprot id: L8ELM1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1265868:SRIM RS33480
gene id: 1265868:SRIM_RS33480
uniprot id: L8ET18
names: Subcellular Location Annotation
messages: Cytoplasm

1265868:SRIM RS10335
gene id: 1265868:SRIM_RS10335
uniprot id: A0A8A1UIG3
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1265868:SRIM RS06560
gene id: 1265868:SRIM_RS06560
uniprot id: L8EET8
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS03830
gene id: 1265868:SRIM_RS03830
uniprot id: A0A8A1UKG7
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS18915
gene id: 1265868:SRIM_RS18915
uniprot id: L8EG81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1265868:SRIM RS21765
gene id: 1265868:SRIM_RS21765
uniprot id: L8F0W3
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS18290
gene id: 1265868:SRIM_RS18290
uniprot id: A0A8A1UPJ8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1265868:SRIM RS19110
gene id: 1265868:SRIM_RS19110
uniprot id: L8EPM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1265868:SRIM RS30130
gene id: 1265868:SRIM_RS30130
uniprot id: L8EKA4
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS10365
gene id: 1265868:SRIM_RS10365
uniprot id: L8EKY7
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS16130
gene id: 1265868:SRIM_RS16130
uniprot id: L8EIR5
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1265868:SRIM RS29215
gene id: 1265868:SRIM_RS29215
uniprot id: A0A8A1USW3
names: Similarity
messages: Belongs to the bacterial phospholipase C family.

1265868:SRIM RS30465
gene id: 1265868:SRIM_RS30465
uniprot id: L8EMA5
names: Similarity
messages: Belongs to the Dps family.

1265868:SRIM RS00265
gene id: 1265868:SRIM_RS00265
uniprot id: L8EZR2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1265868:SRIM RS33950
gene id: 1265868:SRIM_RS33950
uniprot id: L8EIC4
names: Similarity
messages: Belongs to the DszC flavin monooxygenase family.

1265868:SRIM RS29830
gene id: 1265868:SRIM_RS29830
uniprot id: A0A8A1V058
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1265868:SRIM RS03680
gene id: 1265868:SRIM_RS03680
uniprot id: A0A8A1UN69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1265868:SRIM RS35910
gene id: 1265868:SRIM_RS35910
uniprot id: L8ERJ8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1265868:SRIM RS34745
gene id: 1265868:SRIM_RS34745
uniprot id: L8EI73
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS17960
gene id: 1265868:SRIM_RS17960
uniprot id: L8ESR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS20050
gene id: 1265868:SRIM_RS20050
uniprot id: L8EVU7
names: Similarity
messages: Belongs to the GARS family.

1265868:SRIM RS33835
gene id: 1265868:SRIM_RS33835
uniprot id: L8ET84
names: Similarity
messages: Belongs to the cytochrome P450 family.

1265868:SRIM RS30785
gene id: 1265868:SRIM_RS30785
uniprot id: L8ESD4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1265868:SRIM RS31525
gene id: 1265868:SRIM_RS31525
uniprot id: L8EZD0
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS06880
gene id: 1265868:SRIM_RS06880
uniprot id: A0A8A1UJ06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1265868:SRIM RS23790
gene id: 1265868:SRIM_RS23790
uniprot id: L8ESY2
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1265868:SRIM RS09690
gene id: 1265868:SRIM_RS09690
uniprot id: L8EDE1
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1265868:SRIM RS16115
gene id: 1265868:SRIM_RS16115
uniprot id: L8ELJ3
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1265868:SRIM RS10150
gene id: 1265868:SRIM_RS10150
uniprot id: L8ELV9
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS18520
gene id: 1265868:SRIM_RS18520
uniprot id: A0A8A1UM53
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1265868:SRIM RS18970
gene id: 1265868:SRIM_RS18970
uniprot id: L8EML3
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS32225
gene id: 1265868:SRIM_RS32225
uniprot id: A0A8A1UY25
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1265868:SRIM RS13870
gene id: 1265868:SRIM_RS13870
uniprot id: L8EE64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1265868:SRIM RS27030
gene id: 1265868:SRIM_RS27030
uniprot id: L8EJ08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Membrane

1265868:SRIM RS36565
gene id: 1265868:SRIM_RS36565
uniprot id: A0A8A1V4L9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1265868:SRIM RS06275
gene id: 1265868:SRIM_RS06275
uniprot id: L8EJS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1265868:SRIM RS40455
gene id: 1265868:SRIM_RS40455
uniprot id: L8EY47
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS09360
gene id: 1265868:SRIM_RS09360
uniprot id: L8EHU0
names: Similarity
messages: Belongs to the peptidase S33 family.

1265868:SRIM RS13510
gene id: 1265868:SRIM_RS13510
uniprot id: A0A8A1UKI5
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1265868:SRIM RS26640
gene id: 1265868:SRIM_RS26640
uniprot id: L8ETQ0
names: Function
names: Similarity
names: Subunit
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.
messages: Homotrimer.

1265868:SRIM RS23880
gene id: 1265868:SRIM_RS23880
uniprot id: A0A8A1V0Y5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1265868:SRIM RS28800
gene id: 1265868:SRIM_RS28800
uniprot id: L8ER49
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1265868:SRIM RS06790
gene id: 1265868:SRIM_RS06790
uniprot id: L8EKE7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

1265868:SRIM RS20835
gene id: 1265868:SRIM_RS20835
uniprot id: L8EWI1
names: Similarity
messages: Belongs to the LOR family.

1265868:SRIM RS32095
gene id: 1265868:SRIM_RS32095
uniprot id: L8EUI8
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS02315
gene id: 1265868:SRIM_RS02315
uniprot id: A0A8A1UMN5
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS16060
gene id: 1265868:SRIM_RS16060
uniprot id: L8EMP2
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS19575
gene id: 1265868:SRIM_RS19575
uniprot id: L8EW36
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1265868:SRIM RS16655
gene id: 1265868:SRIM_RS16655
uniprot id: L8EP94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1265868:SRIM RS16510
gene id: 1265868:SRIM_RS16510
uniprot id: L8EEX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1265868:SRIM RS04955
gene id: 1265868:SRIM_RS04955
uniprot id: L8EV05
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1265868:SRIM RS21915
gene id: 1265868:SRIM_RS21915
uniprot id: L8F4M2
names: Similarity
messages: Belongs to the peptidase M24B family.

1265868:SRIM RS28995
gene id: 1265868:SRIM_RS28995
uniprot id: L8EQ30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1265868:SRIM RS10600
gene id: 1265868:SRIM_RS10600
uniprot id: A0A8A1UJ58
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1265868:SRIM RS07580
gene id: 1265868:SRIM_RS07580
uniprot id: L8ELV0
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS10470
gene id: 1265868:SRIM_RS10470
uniprot id: L8EFS0
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1265868:SRIM RS36060
gene id: 1265868:SRIM_RS36060
uniprot id: L8ERC2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M.tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins). In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides.
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer.
messages: In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.
messages: In the N-terminal section; belongs to the LPG synthetase family.
messages: Membrane

1265868:SRIM RS25525
gene id: 1265868:SRIM_RS25525
uniprot id: L8EKG1
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1265868:SRIM RS32030
gene id: 1265868:SRIM_RS32030
uniprot id: L8EVS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1265868:SRIM RS40425
gene id: 1265868:SRIM_RS40425
uniprot id: A0A8A1V0K0
names: Similarity
messages: Belongs to the CdaR family.

1265868:SRIM RS06980
gene id: 1265868:SRIM_RS06980
uniprot id: L8EIV3
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS36165
gene id: 1265868:SRIM_RS36165
uniprot id: L8ETE6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1265868:SRIM RS06280
gene id: 1265868:SRIM_RS06280
uniprot id: A0A8A1V2K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1265868:SRIM RS34665
gene id: 1265868:SRIM_RS34665
uniprot id: A0A8A1UZ93
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1265868:SRIM RS26005
gene id: 1265868:SRIM_RS26005
uniprot id: L8EFF0
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1265868:SRIM RS14140
gene id: 1265868:SRIM_RS14140
uniprot id: A0A8A1UNU4
names: Similarity
messages: Belongs to the peptidase S8 family.

1265868:SRIM RS32180
gene id: 1265868:SRIM_RS32180
uniprot id: A0A8A1UZR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

1265868:SRIM RS18925
gene id: 1265868:SRIM_RS18925
uniprot id: L8EF41
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1265868:SRIM RS11405
gene id: 1265868:SRIM_RS11405
uniprot id: L8EI51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1265868:SRIM RS21615
gene id: 1265868:SRIM_RS21615
uniprot id: A0A8A1UQ06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

1265868:SRIM RS10000
gene id: 1265868:SRIM_RS10000
uniprot id: L8EMG7
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

1265868:SRIM RS14870
gene id: 1265868:SRIM_RS14870
uniprot id: L8ES55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1265868:SRIM RS29300
gene id: 1265868:SRIM_RS29300
uniprot id: L8EIM4
names: Cofactor
messages: Binds 1 FAD per subunit.

1265868:SRIM RS12180
gene id: 1265868:SRIM_RS12180
uniprot id: L8EL94
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family.

1265868:SRIM RS18555
gene id: 1265868:SRIM_RS18555
uniprot id: L8EUT8
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1265868:SRIM RS15975
gene id: 1265868:SRIM_RS15975
uniprot id: L8EH86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1265868:SRIM RS10980
gene id: 1265868:SRIM_RS10980
uniprot id: A0A8A1UYX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1265868:SRIM RS22150
gene id: 1265868:SRIM_RS22150
uniprot id: A0A8A1USU8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1265868:SRIM RS36310
gene id: 1265868:SRIM_RS36310
uniprot id: L8ETW0
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1265868:SRIM RS13190
gene id: 1265868:SRIM_RS13190
uniprot id: L8EFK3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

1265868:SRIM RS24995
gene id: 1265868:SRIM_RS24995
uniprot id: L8ES35
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS15830
gene id: 1265868:SRIM_RS15830
uniprot id: L8ESE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1265868:SRIM RS27130
gene id: 1265868:SRIM_RS27130
uniprot id: A0A8A1UQZ5
names: Similarity
messages: Belongs to the peptidase S1C family.

1265868:SRIM RS23445
gene id: 1265868:SRIM_RS23445
uniprot id: A0A8A1UQ39
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

1265868:SRIM RS28275
gene id: 1265868:SRIM_RS28275
uniprot id: L8EV44
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS19590
gene id: 1265868:SRIM_RS19590
uniprot id: L8EUV1
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1265868:SRIM RS18560
gene id: 1265868:SRIM_RS18560
uniprot id: L8ETK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1265868:SRIM RS12195
gene id: 1265868:SRIM_RS12195
uniprot id: L8EMK9
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1265868:SRIM RS27800
gene id: 1265868:SRIM_RS27800
uniprot id: A0A8A1UXH2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M7 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Secreted

1265868:SRIM RS16685
gene id: 1265868:SRIM_RS16685
uniprot id: L8F2K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1265868:SRIM RS32890
gene id: 1265868:SRIM_RS32890
uniprot id: L8EKF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

1265868:SRIM RS08150
gene id: 1265868:SRIM_RS08150
uniprot id: L8ERE7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1265868:SRIM RS19070
gene id: 1265868:SRIM_RS19070
uniprot id: L8EMJ9
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS23200
gene id: 1265868:SRIM_RS23200
uniprot id: L8ER85
names: Similarity
messages: Belongs to the GSP E family.

1265868:SRIM RS21840
gene id: 1265868:SRIM_RS21840
uniprot id: L8F4K3
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS01705
gene id: 1265868:SRIM_RS01705
uniprot id: L8EWA2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS23850
gene id: 1265868:SRIM_RS23850
uniprot id: L8ENW1
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS26145
gene id: 1265868:SRIM_RS26145
uniprot id: L8ESQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.

1265868:SRIM RS27425
gene id: 1265868:SRIM_RS27425
uniprot id: L8EG50
names: Similarity
messages: Belongs to the peptidase S16 family.

1265868:SRIM RS01355
gene id: 1265868:SRIM_RS01355
uniprot id: L8EVQ3
names: Similarity
messages: Belongs to the cytochrome P450 family.

1265868:SRIM RS07145
gene id: 1265868:SRIM_RS07145
uniprot id: L8EQU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1265868:SRIM RS33165
gene id: 1265868:SRIM_RS33165
uniprot id: L8ENJ7
names: Similarity
messages: Belongs to the cytochrome P450 family.

1265868:SRIM RS31490
gene id: 1265868:SRIM_RS31490
uniprot id: A0A8A1V0V1
names: Function
names: Similarity
messages: Belongs to the cyanase family.
messages: Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.

1265868:SRIM RS02750
gene id: 1265868:SRIM_RS02750
uniprot id: L8EU22
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS17900
gene id: 1265868:SRIM_RS17900
uniprot id: A0A8A1UQP0
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS25125
gene id: 1265868:SRIM_RS25125
uniprot id: L8ETE3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

1265868:SRIM RS27265
gene id: 1265868:SRIM_RS27265
uniprot id: L8EEI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS26000
gene id: 1265868:SRIM_RS26000
uniprot id: L8EF74
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS31870
gene id: 1265868:SRIM_RS31870
uniprot id: L8EUM5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1265868:SRIM RS22625
gene id: 1265868:SRIM_RS22625
uniprot id: L8ENS2
names: Subunit
messages: Homodimer.

1265868:SRIM RS10850
gene id: 1265868:SRIM_RS10850
uniprot id: L8ERY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1265868:SRIM RS10965
gene id: 1265868:SRIM_RS10965
uniprot id: A0A8A1UIR7
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS07265
gene id: 1265868:SRIM_RS07265
uniprot id: L8EU83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1265868:SRIM RS25940
gene id: 1265868:SRIM_RS25940
uniprot id: A0A8A1UYE1
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

1265868:SRIM RS14730
gene id: 1265868:SRIM_RS14730
uniprot id: L8F172
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1265868:SRIM RS30875
gene id: 1265868:SRIM_RS30875
uniprot id: L8ETH3
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

1265868:SRIM RS24580
gene id: 1265868:SRIM_RS24580
uniprot id: L8EUU2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1265868:SRIM RS23740
gene id: 1265868:SRIM_RS23740
uniprot id: L8EUE4
names: Subcellular Location Annotation
messages: Mitochondrion

1265868:SRIM RS00930
gene id: 1265868:SRIM_RS00930
uniprot id: A0A8A1UGE6
names: Similarity
messages: Belongs to the peptidase S1 family.

1265868:SRIM RS09820
gene id: 1265868:SRIM_RS09820
uniprot id: A0A8A1V587
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1265868:SRIM RS35545
gene id: 1265868:SRIM_RS35545
uniprot id: L8EQA5
names: Similarity
messages: Belongs to the FPG family.

1265868:SRIM RS09965
gene id: 1265868:SRIM_RS09965
uniprot id: L8EMG2
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS01590
gene id: 1265868:SRIM_RS01590
uniprot id: L8EX57
names: Similarity
messages: Belongs to the thioesterase family.

1265868:SRIM RS18765
gene id: 1265868:SRIM_RS18765
uniprot id: L8EXJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1265868:SRIM RS19970
gene id: 1265868:SRIM_RS19970
uniprot id: L8EWM3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1265868:SRIM RS26420
gene id: 1265868:SRIM_RS26420
uniprot id: L8EEZ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

1265868:SRIM RS16470
gene id: 1265868:SRIM_RS16470
uniprot id: A0A8A1UMB8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1265868:SRIM RS34855
gene id: 1265868:SRIM_RS34855
uniprot id: A0A8A1UWV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1265868:SRIM RS36755
gene id: 1265868:SRIM_RS36755
uniprot id: L8EK72
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1265868:SRIM RS14590
gene id: 1265868:SRIM_RS14590
uniprot id: L8EYH8
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1265868:SRIM RS06630
gene id: 1265868:SRIM_RS06630
uniprot id: L8ETS7
names: Similarity
messages: Belongs to the barstar family.

1265868:SRIM RS40360
gene id: 1265868:SRIM_RS40360
uniprot id: L8EXC0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS19120
gene id: 1265868:SRIM_RS19120
uniprot id: L8ELK1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1265868:SRIM RS34840
gene id: 1265868:SRIM_RS34840
uniprot id: L8EH22
names: Similarity
messages: Belongs to the DapA family.

1265868:SRIM RS21810
gene id: 1265868:SRIM_RS21810
uniprot id: L8F0L7
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS05635
gene id: 1265868:SRIM_RS05635
uniprot id: L8ESI3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1265868:SRIM RS28990
gene id: 1265868:SRIM_RS28990
uniprot id: L8ENZ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1265868:SRIM RS17075
gene id: 1265868:SRIM_RS17075
uniprot id: L8EYM7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS05170
gene id: 1265868:SRIM_RS05170
uniprot id: L8EI28
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1265868:SRIM RS26255
gene id: 1265868:SRIM_RS26255
uniprot id: L8EW35
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1265868:SRIM RS11325
gene id: 1265868:SRIM_RS11325
uniprot id: L8EQ90
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS08245
gene id: 1265868:SRIM_RS08245
uniprot id: A0A8A1UJN2
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

1265868:SRIM RS19930
gene id: 1265868:SRIM_RS19930
uniprot id: L8EVW5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Cytoplasm
messages: Homodimer.

1265868:SRIM RS05770
gene id: 1265868:SRIM_RS05770
uniprot id: L8EST7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1265868:SRIM RS29620
gene id: 1265868:SRIM_RS29620
uniprot id: A0A8A1UYE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1265868:SRIM RS12275
gene id: 1265868:SRIM_RS12275
uniprot id: L8ENR8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1265868:SRIM RS23625
gene id: 1265868:SRIM_RS23625
uniprot id: L8EQ66
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1265868:SRIM RS24545
gene id: 1265868:SRIM_RS24545
uniprot id: L8EY20
names: Subcellular Location Annotation
messages: Cell membrane

1265868:SRIM RS17965
gene id: 1265868:SRIM_RS17965
uniprot id: L8EWV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1265868:SRIM RS39215
gene id: 1265868:SRIM_RS39215
uniprot id: L8F020
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1265868:SRIM RS10440
gene id: 1265868:SRIM_RS10440
uniprot id: L8ELB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1265868:SRIM RS11425
gene id: 1265868:SRIM_RS11425
uniprot id: L8EJ44
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1265868:SRIM RS30155
gene id: 1265868:SRIM_RS30155
uniprot id: L8EKB0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1265868:SRIM RS34660
gene id: 1265868:SRIM_RS34660
uniprot id: L8EH98
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1265868:SRIM RS39790
gene id: 1265868:SRIM_RS39790
uniprot id: A0A8A1V057
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

1265868:SRIM RS04305
gene id: 1265868:SRIM_RS04305
uniprot id: L8EGN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1265868:SRIM RS07140
gene id: 1265868:SRIM_RS07140
uniprot id: L8ER03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1265868:SRIM RS26885
gene id: 1265868:SRIM_RS26885
uniprot id: L8EQX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1265868:SRIM RS10685
gene id: 1265868:SRIM_RS10685
uniprot id: L8EFL2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1265868:SRIM RS33375
gene id: 1265868:SRIM_RS33375
uniprot id: L8EQN1
names: Caution
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS15725
gene id: 1265868:SRIM_RS15725
uniprot id: A0A8A1ULK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1265868:SRIM RS18240
gene id: 1265868:SRIM_RS18240
uniprot id: L8ENH1
names: Cofactor
names: Similarity
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.

1265868:SRIM RS06725
gene id: 1265868:SRIM_RS06725
uniprot id: L8EPH9
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS23360
gene id: 1265868:SRIM_RS23360
uniprot id: L8ENJ9
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

1265868:SRIM RS34440
gene id: 1265868:SRIM_RS34440
uniprot id: A0A8A1UWN0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1265868:SRIM RS09585
gene id: 1265868:SRIM_RS09585
uniprot id: L8EL28
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1265868:SRIM RS02700
gene id: 1265868:SRIM_RS02700
uniprot id: A0A8A1UMT0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1265868:SRIM RS33645
gene id: 1265868:SRIM_RS33645
uniprot id: L8ESI0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1265868:SRIM RS31150
gene id: 1265868:SRIM_RS31150
uniprot id: L8EFZ6
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

1265868:SRIM RS31045
gene id: 1265868:SRIM_RS31045
uniprot id: L8EUB9
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS32620
gene id: 1265868:SRIM_RS32620
uniprot id: A0A8A1UZY2
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS29095
gene id: 1265868:SRIM_RS29095
uniprot id: L8EJA3
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

1265868:SRIM RS08580
gene id: 1265868:SRIM_RS08580
uniprot id: L8EJM1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1265868:SRIM RS09655
gene id: 1265868:SRIM_RS09655
uniprot id: L8EIK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1265868:SRIM RS24855
gene id: 1265868:SRIM_RS24855
uniprot id: A0A8A1V120
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1265868:SRIM RS06765
gene id: 1265868:SRIM_RS06765
uniprot id: L8EQR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1265868:SRIM RS40355
gene id: 1265868:SRIM_RS40355
uniprot id: L8EY26
names: Similarity
messages: Belongs to the cytochrome P450 family.

1265868:SRIM RS31920
gene id: 1265868:SRIM_RS31920
uniprot id: L8EUL8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1265868:SRIM RS33290
gene id: 1265868:SRIM_RS33290
uniprot id: L8EU06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.
messages: Secreted

1265868:SRIM RS24125
gene id: 1265868:SRIM_RS24125
uniprot id: A0A8A1USM9
names: Similarity
messages: Belongs to the CsoR family.

1265868:SRIM RS27315
gene id: 1265868:SRIM_RS27315
uniprot id: A0A8A1USW2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1265868:SRIM RS06640
gene id: 1265868:SRIM_RS06640
uniprot id: L8EQP4
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1265868:SRIM RS15590
gene id: 1265868:SRIM_RS15590
uniprot id: A0A8A1UNE1
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1265868:SRIM RS10305
gene id: 1265868:SRIM_RS10305
uniprot id: L8EJZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1265868:SRIM RS18935
gene id: 1265868:SRIM_RS18935
uniprot id: L8EF84
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1265868:SRIM RS39060
gene id: 1265868:SRIM_RS39060
uniprot id: L8ELD5
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1265868:SRIM RS06495
gene id: 1265868:SRIM_RS06495
uniprot id: L8EGF0
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS35180
gene id: 1265868:SRIM_RS35180
uniprot id: L8ET83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1265868:SRIM RS28360
gene id: 1265868:SRIM_RS28360
uniprot id: L8EXX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1265868:SRIM RS21795
gene id: 1265868:SRIM_RS21795
uniprot id: A0A8A1USN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1265868:SRIM RS32390
gene id: 1265868:SRIM_RS32390
uniprot id: L8EGT6
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

1265868:SRIM RS39660
gene id: 1265868:SRIM_RS39660
uniprot id: L8EMK8
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1265868:SRIM RS30005
gene id: 1265868:SRIM_RS30005
uniprot id: L8EY75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1265868:SRIM RS33930
gene id: 1265868:SRIM_RS33930
uniprot id: L8EHB3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1265868:SRIM RS15250
gene id: 1265868:SRIM_RS15250
uniprot id: L8EJW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS00280
gene id: 1265868:SRIM_RS00280
uniprot id: L8EZW0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1265868:SRIM RS07685
gene id: 1265868:SRIM_RS07685
uniprot id: L8ETN4
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS24005
gene id: 1265868:SRIM_RS24005
uniprot id: L8EFJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1265868:SRIM RS20790
gene id: 1265868:SRIM_RS20790
uniprot id: A0A8A1UPM2
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1265868:SRIM RS13495
gene id: 1265868:SRIM_RS13495
uniprot id: L8EVN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1265868:SRIM RS31005
gene id: 1265868:SRIM_RS31005
uniprot id: L8EQZ4
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1265868:SRIM RS35415
gene id: 1265868:SRIM_RS35415
uniprot id: L8ENA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS11305
gene id: 1265868:SRIM_RS11305
uniprot id: A0A8A1V5B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1265868:SRIM RS21130
gene id: 1265868:SRIM_RS21130
uniprot id: L8F1J2
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS31180
gene id: 1265868:SRIM_RS31180
uniprot id: A0A8A1V2M7
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1265868:SRIM RS07515
gene id: 1265868:SRIM_RS07515
uniprot id: L8EIA4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1265868:SRIM RS24265
gene id: 1265868:SRIM_RS24265
uniprot id: L8ENG5
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS36345
gene id: 1265868:SRIM_RS36345
uniprot id: L8ESQ2
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1265868:SRIM RS08170
gene id: 1265868:SRIM_RS08170
uniprot id: L8ESH5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1265868:SRIM RS23545
gene id: 1265868:SRIM_RS23545
uniprot id: L8EKL0
names: Similarity
messages: Belongs to the group II decarboxylase family.

1265868:SRIM RS06535
gene id: 1265868:SRIM_RS06535
uniprot id: A0A8A1UX85
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1265868:SRIM RS16220
gene id: 1265868:SRIM_RS16220
uniprot id: L8EIP7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

1265868:SRIM RS24505
gene id: 1265868:SRIM_RS24505
uniprot id: L8EV85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase group 1 family. MshA subfamily.
messages: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
messages: Homodimer.

1265868:SRIM RS29800
gene id: 1265868:SRIM_RS29800
uniprot id: L8EYB7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1265868:SRIM RS35970
gene id: 1265868:SRIM_RS35970
uniprot id: A0A8A1V336
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS32100
gene id: 1265868:SRIM_RS32100
uniprot id: L8EGI4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1265868:SRIM RS02085
gene id: 1265868:SRIM_RS02085
uniprot id: L8EJJ1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1265868:SRIM RS18920
gene id: 1265868:SRIM_RS18920
uniprot id: L8EFV6
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS22505
gene id: 1265868:SRIM_RS22505
uniprot id: L8EF20
names: Similarity
messages: Belongs to the pirin family.

1265868:SRIM RS25585
gene id: 1265868:SRIM_RS25585
uniprot id: L8EN07
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS31110
gene id: 1265868:SRIM_RS31110
uniprot id: A0A8A1V0N6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1265868:SRIM RS32615
gene id: 1265868:SRIM_RS32615
uniprot id: A0A8A1UY85
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1265868:SRIM RS21805
gene id: 1265868:SRIM_RS21805
uniprot id: L8F1N4
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

1265868:SRIM RS29180
gene id: 1265868:SRIM_RS29180
uniprot id: A0A8A1V050
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

1265868:SRIM RS09435
gene id: 1265868:SRIM_RS09435
uniprot id: L8EHS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1265868:SRIM RS10780
gene id: 1265868:SRIM_RS10780
uniprot id: A0A8A1URE7
names: Similarity
messages: Belongs to the peptidase C40 family.

1265868:SRIM RS05525
gene id: 1265868:SRIM_RS05525
uniprot id: L8EHL3
names: Similarity
messages: Belongs to the oxoprolinase family.

1265868:SRIM RS21115
gene id: 1265868:SRIM_RS21115
uniprot id: L8F099
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1265868:SRIM RS05455
gene id: 1265868:SRIM_RS05455
uniprot id: L8EKD9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1265868:SRIM RS18550
gene id: 1265868:SRIM_RS18550
uniprot id: L8EUE8
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1265868:SRIM RS18325
gene id: 1265868:SRIM_RS18325
uniprot id: A0A8A1UMR3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1265868:SRIM RS20290
gene id: 1265868:SRIM_RS20290
uniprot id: L8EYX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1265868:SRIM RS04970
gene id: 1265868:SRIM_RS04970
uniprot id: L8ES04
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS27740
gene id: 1265868:SRIM_RS27740
uniprot id: L8EIT1
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS34010
gene id: 1265868:SRIM_RS34010
uniprot id: L8ELQ3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1265868:SRIM RS26940
gene id: 1265868:SRIM_RS26940
uniprot id: L8ERV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS06905
gene id: 1265868:SRIM_RS06905
uniprot id: L8EIT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1265868:SRIM RS23600
gene id: 1265868:SRIM_RS23600
uniprot id: L8EQ72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS17160
gene id: 1265868:SRIM_RS17160
uniprot id: L8F2B5
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1265868:SRIM RS06900
gene id: 1265868:SRIM_RS06900
uniprot id: L8EN30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1265868:SRIM RS08155
gene id: 1265868:SRIM_RS08155
uniprot id: L8EVI8
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS26770
gene id: 1265868:SRIM_RS26770
uniprot id: L8EFA6
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS27540
gene id: 1265868:SRIM_RS27540
uniprot id: L8EMZ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1265868:SRIM RS31685
gene id: 1265868:SRIM_RS31685
uniprot id: L8EWG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1265868:SRIM RS20600
gene id: 1265868:SRIM_RS20600
uniprot id: L8EXZ5
names: Similarity
messages: Belongs to the CobH/CbiC family.

1265868:SRIM RS16645
gene id: 1265868:SRIM_RS16645
uniprot id: L8ELA1
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1265868:SRIM RS06515
gene id: 1265868:SRIM_RS06515
uniprot id: L8EDT4
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1265868:SRIM RS09235
gene id: 1265868:SRIM_RS09235
uniprot id: L8EMU2
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS16315
gene id: 1265868:SRIM_RS16315
uniprot id: L8ELX7
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

1265868:SRIM RS26265
gene id: 1265868:SRIM_RS26265
uniprot id: L8ET66
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Cys-Ser-Gly.
messages: Cytoplasm

1265868:SRIM RS24880
gene id: 1265868:SRIM_RS24880
uniprot id: A0A8A1UQT8
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

1265868:SRIM RS35620
gene id: 1265868:SRIM_RS35620
uniprot id: L8EQB9
names: Similarity
messages: Belongs to the CapA family.

1265868:SRIM RS30495
gene id: 1265868:SRIM_RS30495
uniprot id: L8ERG3
names: Similarity
messages: Belongs to the FPG family.

1265868:SRIM RS32545
gene id: 1265868:SRIM_RS32545
uniprot id: L8ER78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1265868:SRIM RS02955
gene id: 1265868:SRIM_RS02955
uniprot id: L8EEE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1265868:SRIM RS10505
gene id: 1265868:SRIM_RS10505
uniprot id: L8EEW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS08960
gene id: 1265868:SRIM_RS08960
uniprot id: L8EHF4
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1265868:SRIM RS15730
gene id: 1265868:SRIM_RS15730
uniprot id: L8ED70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1265868:SRIM RS05140
gene id: 1265868:SRIM_RS05140
uniprot id: A0A8A1UJ70
names: Function
names: Subcellular Location Annotation
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

1265868:SRIM RS13290
gene id: 1265868:SRIM_RS13290
uniprot id: L8EZI2
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

1265868:SRIM RS35780
gene id: 1265868:SRIM_RS35780
uniprot id: L8ERM1
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1265868:SRIM RS15795
gene id: 1265868:SRIM_RS15795
uniprot id: A0A8A1UMW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS34790
gene id: 1265868:SRIM_RS34790
uniprot id: L8EG13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1265868:SRIM RS08110
gene id: 1265868:SRIM_RS08110
uniprot id: L8ERA9
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

1265868:SRIM RS30355
gene id: 1265868:SRIM_RS30355
uniprot id: L8EQS1
names: Similarity
messages: Belongs to the peptidase M16 family.

1265868:SRIM RS38845
gene id: 1265868:SRIM_RS38845
uniprot id: A0A8A1V374
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS24940
gene id: 1265868:SRIM_RS24940
uniprot id: L8EW69
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS10515
gene id: 1265868:SRIM_RS10515
uniprot id: L8EDW1
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS21295
gene id: 1265868:SRIM_RS21295
uniprot id: L8F0K5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1265868:SRIM RS31945
gene id: 1265868:SRIM_RS31945
uniprot id: L8EUL3
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1265868:SRIM RS24745
gene id: 1265868:SRIM_RS24745
uniprot id: L8EHR8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

1265868:SRIM RS26745
gene id: 1265868:SRIM_RS26745
uniprot id: L8EFA2
names: Similarity
messages: Belongs to the FBPase class 2 family.

1265868:SRIM RS18355
gene id: 1265868:SRIM_RS18355
uniprot id: L8ENY9
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1265868:SRIM RS23945
gene id: 1265868:SRIM_RS23945
uniprot id: L8ET09
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS03260
gene id: 1265868:SRIM_RS03260
uniprot id: L8EHY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

1265868:SRIM RS18695
gene id: 1265868:SRIM_RS18695
uniprot id: L8ETI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1265868:SRIM RS40240
gene id: 1265868:SRIM_RS40240
uniprot id: A0A8A1UZB3
names: Subcellular Location Annotation
messages: Cell membrane

1265868:SRIM RS11035
gene id: 1265868:SRIM_RS11035
uniprot id: L8ERS4
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1265868:SRIM RS05675
gene id: 1265868:SRIM_RS05675
uniprot id: L8EVV3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1265868:SRIM RS16030
gene id: 1265868:SRIM_RS16030
uniprot id: L8EMU4
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

1265868:SRIM RS07435
gene id: 1265868:SRIM_RS07435
uniprot id: L8EDA5
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

1265868:SRIM RS13630
gene id: 1265868:SRIM_RS13630
uniprot id: L8EL75
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1265868:SRIM RS08530
gene id: 1265868:SRIM_RS08530
uniprot id: L8EJL1
names: Similarity
messages: Belongs to the peptidase S1 family.

1265868:SRIM RS35420
gene id: 1265868:SRIM_RS35420
uniprot id: A0A8A1V4J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS18605
gene id: 1265868:SRIM_RS18605
uniprot id: L8EUS4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1265868:SRIM RS28355
gene id: 1265868:SRIM_RS28355
uniprot id: L8ETU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1265868:SRIM RS10810
gene id: 1265868:SRIM_RS10810
uniprot id: L8EUY9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS10740
gene id: 1265868:SRIM_RS10740
uniprot id: A0A8A1UL19
names: Similarity
messages: Belongs to the arsA ATPase family.

1265868:SRIM RS07120
gene id: 1265868:SRIM_RS07120
uniprot id: L8EEJ3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1265868:SRIM RS05160
gene id: 1265868:SRIM_RS05160
uniprot id: L8EF90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterotetramer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits of ACCase subunit beta/alpha.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the AccA family.
messages: In the N-terminal section; belongs to the AccD/PCCB family.

1265868:SRIM RS16705
gene id: 1265868:SRIM_RS16705
uniprot id: L8EYT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1265868:SRIM RS20460
gene id: 1265868:SRIM_RS20460
uniprot id: L8EXS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS26365
gene id: 1265868:SRIM_RS26365
uniprot id: L8ET88
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1265868:SRIM RS24750
gene id: 1265868:SRIM_RS24750
uniprot id: A0A8A1URM9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1265868:SRIM RS34500
gene id: 1265868:SRIM_RS34500
uniprot id: L8ELY6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1265868:SRIM RS22715
gene id: 1265868:SRIM_RS22715
uniprot id: L8EMU5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1265868:SRIM RS21430
gene id: 1265868:SRIM_RS21430
uniprot id: L8F1F1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1265868:SRIM RS05390
gene id: 1265868:SRIM_RS05390
uniprot id: L8EGC4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS30225
gene id: 1265868:SRIM_RS30225
uniprot id: A0A8A1UU54
names: Similarity
messages: Belongs to the EccE family.

1265868:SRIM RS25075
gene id: 1265868:SRIM_RS25075
uniprot id: A0A8A1UQ17
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1265868:SRIM RS03995
gene id: 1265868:SRIM_RS03995
uniprot id: A0A8A1UG19
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS16340
gene id: 1265868:SRIM_RS16340
uniprot id: L8ELY0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1265868:SRIM RS21505
gene id: 1265868:SRIM_RS21505
uniprot id: L8F1G7
names: Subcellular Location Annotation
messages: Cytoplasm

1265868:SRIM RS41870
gene id: 1265868:SRIM_RS41870
uniprot id: A0A8A1V744
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1265868:SRIM RS06490
gene id: 1265868:SRIM_RS06490
uniprot id: L8EKP3
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS14715
gene id: 1265868:SRIM_RS14715
uniprot id: L8EYK3
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

1265868:SRIM RS28865
gene id: 1265868:SRIM_RS28865
uniprot id: L8EJK2
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS24925
gene id: 1265868:SRIM_RS24925
uniprot id: L8ET95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

1265868:SRIM RS23780
gene id: 1265868:SRIM_RS23780
uniprot id: A0A8A1UVG7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1265868:SRIM RS23915
gene id: 1265868:SRIM_RS23915
uniprot id: L8ENN5
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1265868:SRIM RS22560
gene id: 1265868:SRIM_RS22560
uniprot id: L8EMY2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1265868:SRIM RS21480
gene id: 1265868:SRIM_RS21480
uniprot id: L8F1G2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1265868:SRIM RS16710
gene id: 1265868:SRIM_RS16710
uniprot id: L8F2J7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Cell membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

1265868:SRIM RS40050
gene id: 1265868:SRIM_RS40050
uniprot id: L8EWU8
names: Similarity
messages: Belongs to the DapA family.

1265868:SRIM RS18810
gene id: 1265868:SRIM_RS18810
uniprot id: L8ETF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1265868:SRIM RS32870
gene id: 1265868:SRIM_RS32870
uniprot id: L8EPM2
names: Similarity
messages: Belongs to the CdaR family.

1265868:SRIM RS38520
gene id: 1265868:SRIM_RS38520
uniprot id: L8EL35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS06915
gene id: 1265868:SRIM_RS06915
uniprot id: L8EJT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1265868:SRIM RS24310
gene id: 1265868:SRIM_RS24310
uniprot id: L8EST0
names: Caution
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lacks the conserved His residue that binds heme iron in the nitrobindin family.

1265868:SRIM RS19045
gene id: 1265868:SRIM_RS19045
uniprot id: A0A8A1UPY4
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS33160
gene id: 1265868:SRIM_RS33160
uniprot id: L8EPH7
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1265868:SRIM RS18940
gene id: 1265868:SRIM_RS18940
uniprot id: L8EG87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1265868:SRIM RS07355
gene id: 1265868:SRIM_RS07355
uniprot id: L8EG47
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1265868:SRIM RS29270
gene id: 1265868:SRIM_RS29270
uniprot id: L8EJW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1265868:SRIM RS27495
gene id: 1265868:SRIM_RS27495
uniprot id: L8EP44
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1265868:SRIM RS00500
gene id: 1265868:SRIM_RS00500
uniprot id: L8F3H3
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS16910
gene id: 1265868:SRIM_RS16910
uniprot id: L8EYQ5
names: Subcellular Location Annotation
messages: Cell membrane

1265868:SRIM RS32905
gene id: 1265868:SRIM_RS32905
uniprot id: A0A8A1V0M7
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS05705
gene id: 1265868:SRIM_RS05705
uniprot id: L8ERM4
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

1265868:SRIM RS32425
gene id: 1265868:SRIM_RS32425
uniprot id: L8EI61
names: Similarity
messages: Belongs to the peptidase S8 family.

1265868:SRIM RS15045
gene id: 1265868:SRIM_RS15045
uniprot id: A0A8A1UN54
names: Similarity
messages: Belongs to the peptidase C40 family.

1265868:SRIM RS20100
gene id: 1265868:SRIM_RS20100
uniprot id: L8EGM6
names: Similarity
messages: Belongs to the HsdR family.

1265868:SRIM RS28980
gene id: 1265868:SRIM_RS28980
uniprot id: L8EP79
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS20025
gene id: 1265868:SRIM_RS20025
uniprot id: L8EVV2
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1265868:SRIM RS12550
gene id: 1265868:SRIM_RS12550
uniprot id: L8EZI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

1265868:SRIM RS03930
gene id: 1265868:SRIM_RS03930
uniprot id: L8EQT9
names: Similarity
messages: Belongs to the peptidase S1 family.

1265868:SRIM RS02790
gene id: 1265868:SRIM_RS02790
uniprot id: L8ETB2
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1265868:SRIM RS15190
gene id: 1265868:SRIM_RS15190
uniprot id: A0A8A1ULB6
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1265868:SRIM RS05300
gene id: 1265868:SRIM_RS05300
uniprot id: L8EJE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

1265868:SRIM RS10960
gene id: 1265868:SRIM_RS10960
uniprot id: L8EUV4
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1265868:SRIM RS32735
gene id: 1265868:SRIM_RS32735
uniprot id: L8ES40
names: Similarity
messages: Belongs to the TPP enzyme family.

1265868:SRIM RS04650
gene id: 1265868:SRIM_RS04650
uniprot id: A0A8A1V0Z7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1265868:SRIM RS21275
gene id: 1265868:SRIM_RS21275
uniprot id: L8F1L9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1265868:SRIM RS11375
gene id: 1265868:SRIM_RS11375
uniprot id: L8EJ32
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS37860
gene id: 1265868:SRIM_RS37860
uniprot id: L8F033
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1265868:SRIM RS09950
gene id: 1265868:SRIM_RS09950
uniprot id: L8EL52
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1265868:SRIM RS05355
gene id: 1265868:SRIM_RS05355
uniprot id: A0A8A1UG76
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1265868:SRIM RS23685
gene id: 1265868:SRIM_RS23685
uniprot id: L8ERC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1265868:SRIM RS12375
gene id: 1265868:SRIM_RS12375
uniprot id: L8ET48
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1265868:SRIM RS15450
gene id: 1265868:SRIM_RS15450
uniprot id: L8EKU5
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

1265868:SRIM RS16445
gene id: 1265868:SRIM_RS16445
uniprot id: A0A8A1UL70
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1265868:SRIM RS07715
gene id: 1265868:SRIM_RS07715
uniprot id: L8EU44
names: Similarity
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Homohexamer. Assembles into a hexameric ring structure.

1265868:SRIM RS17010
gene id: 1265868:SRIM_RS17010
uniprot id: L8EYK4
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1265868:SRIM RS03510
gene id: 1265868:SRIM_RS03510
uniprot id: L8ESQ4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS09535
gene id: 1265868:SRIM_RS09535
uniprot id: L8EL36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS20840
gene id: 1265868:SRIM_RS20840
uniprot id: L8F0F7
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1265868:SRIM RS08645
gene id: 1265868:SRIM_RS08645
uniprot id: L8EIC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1265868:SRIM RS29390
gene id: 1265868:SRIM_RS29390
uniprot id: A0A8A1UYV5
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1265868:SRIM RS24570
gene id: 1265868:SRIM_RS24570
uniprot id: L8EY16
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS27500
gene id: 1265868:SRIM_RS27500
uniprot id: L8EPA5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1265868:SRIM RS18535
gene id: 1265868:SRIM_RS18535
uniprot id: L8ETK5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1265868:SRIM RS29150
gene id: 1265868:SRIM_RS29150
uniprot id: L8EIB0
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1265868:SRIM RS17985
gene id: 1265868:SRIM_RS17985
uniprot id: L8ESS2
names: Function
names: Similarity
messages: Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
messages: In the C-terminal section; belongs to the radical SAM superfamily. CofH family.
messages: In the N-terminal section; belongs to the radical SAM superfamily. CofG family.

1265868:SRIM RS07735
gene id: 1265868:SRIM_RS07735
uniprot id: L8ETM4
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS40020
gene id: 1265868:SRIM_RS40020
uniprot id: L8F0Q2
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1265868:SRIM RS20690
gene id: 1265868:SRIM_RS20690
uniprot id: L8EWK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1265868:SRIM RS19065
gene id: 1265868:SRIM_RS19065
uniprot id: L8ERV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1265868:SRIM RS09045
gene id: 1265868:SRIM_RS09045
uniprot id: A0A8A1UNS2
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS09105
gene id: 1265868:SRIM_RS09105
uniprot id: L8EKJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1265868:SRIM RS23595
gene id: 1265868:SRIM_RS23595
uniprot id: L8EUH4
names: Similarity
messages: Belongs to the UPF0145 family.

1265868:SRIM RS38450
gene id: 1265868:SRIM_RS38450
uniprot id: L8EUL2
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1265868:SRIM RS02385
gene id: 1265868:SRIM_RS02385
uniprot id: L8EYY7
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1265868:SRIM RS20445
gene id: 1265868:SRIM_RS20445
uniprot id: A0A8A1UPY1
names: Similarity
messages: Belongs to the AAA ATPase family.

1265868:SRIM RS30615
gene id: 1265868:SRIM_RS30615
uniprot id: A0A8A1UX69
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1265868:SRIM RS34225
gene id: 1265868:SRIM_RS34225
uniprot id: L8EFQ9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CoA-transferase III family. Frc subfamily.
messages: Homodimer.
messages: Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS13400
gene id: 1265868:SRIM_RS13400
uniprot id: L8EWS5
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1265868:SRIM RS07780
gene id: 1265868:SRIM_RS07780
uniprot id: L8ESW9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS09020
gene id: 1265868:SRIM_RS09020
uniprot id: L8EFN5
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

1265868:SRIM RS12590
gene id: 1265868:SRIM_RS12590
uniprot id: L8F246
names: Similarity
messages: Belongs to the universal stress protein A family.

1265868:SRIM RS18600
gene id: 1265868:SRIM_RS18600
uniprot id: L8EUD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1265868:SRIM RS18835
gene id: 1265868:SRIM_RS18835
uniprot id: A0A8A1UTK1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1265868:SRIM RS34025
gene id: 1265868:SRIM_RS34025
uniprot id: L8EMZ4
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS39835
gene id: 1265868:SRIM_RS39835
uniprot id: L8EXZ8
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1265868:SRIM RS04565
gene id: 1265868:SRIM_RS04565
uniprot id: L8EE73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS35565
gene id: 1265868:SRIM_RS35565
uniprot id: L8EQF5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1265868:SRIM RS04215
gene id: 1265868:SRIM_RS04215
uniprot id: L8ELB8
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1265868:SRIM RS34800
gene id: 1265868:SRIM_RS34800
uniprot id: L8EF23
names: Similarity
messages: Belongs to the YciI family.

1265868:SRIM RS33630
gene id: 1265868:SRIM_RS33630
uniprot id: A0A8A1V4E9
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1265868:SRIM RS28265
gene id: 1265868:SRIM_RS28265
uniprot id: L8ETY9
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1265868:SRIM RS15470
gene id: 1265868:SRIM_RS15470
uniprot id: L8EGH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1265868:SRIM RS24145
gene id: 1265868:SRIM_RS24145
uniprot id: L8EPS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1265868:SRIM RS24130
gene id: 1265868:SRIM_RS24130
uniprot id: L8ESW3
names: Similarity
messages: Belongs to the PhoU family.
messages: Belongs to the UPF0111 family.

1265868:SRIM RS14875
gene id: 1265868:SRIM_RS14875
uniprot id: L8EMU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1265868:SRIM RS39515
gene id: 1265868:SRIM_RS39515
uniprot id: L8EPT4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1265868:SRIM RS35490
gene id: 1265868:SRIM_RS35490
uniprot id: L8EIX1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1265868:SRIM RS35045
gene id: 1265868:SRIM_RS35045
uniprot id: A0A8A1V317
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1265868:SRIM RS18595
gene id: 1265868:SRIM_RS18595
uniprot id: L8ETK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1265868:SRIM RS10460
gene id: 1265868:SRIM_RS10460
uniprot id: L8EJ54
names: Similarity
messages: Belongs to the YggT family.

1265868:SRIM RS19410
gene id: 1265868:SRIM_RS19410
uniprot id: L8EUY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

1265868:SRIM RS04980
gene id: 1265868:SRIM_RS04980
uniprot id: L8EV00
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1265868:SRIM RS19080
gene id: 1265868:SRIM_RS19080
uniprot id: L8ENU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1265868:SRIM RS39430
gene id: 1265868:SRIM_RS39430
uniprot id: L8EHG6
names: Subcellular Location Annotation
messages: Cytoplasm

1265868:SRIM RS34360
gene id: 1265868:SRIM_RS34360
uniprot id: L8EV26
names: Similarity
messages: Belongs to the bacterial phospholipase C family.

1265868:SRIM RS24290
gene id: 1265868:SRIM_RS24290
uniprot id: A0A8A1UTY3
names: Similarity
messages: Belongs to the Fur family.

1265868:SRIM RS06480
gene id: 1265868:SRIM_RS06480
uniprot id: L8EH84
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

1265868:SRIM RS27195
gene id: 1265868:SRIM_RS27195
uniprot id: L8EHM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS21410
gene id: 1265868:SRIM_RS21410
uniprot id: L8F0E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

1265868:SRIM RS34320
gene id: 1265868:SRIM_RS34320
uniprot id: A0A8A1UVA8
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

1265868:SRIM RS13585
gene id: 1265868:SRIM_RS13585
uniprot id: L8ELG6
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS10730
gene id: 1265868:SRIM_RS10730
uniprot id: L8EE22
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1265868:SRIM RS29640
gene id: 1265868:SRIM_RS29640
uniprot id: L8EF56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1265868:SRIM RS18755
gene id: 1265868:SRIM_RS18755
uniprot id: L8EUP1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1265868:SRIM RS35205
gene id: 1265868:SRIM_RS35205
uniprot id: A0A8A1UY60
names: Similarity
messages: Belongs to the asparagine synthetase family.

1265868:SRIM RS24690
gene id: 1265868:SRIM_RS24690
uniprot id: L8EV55
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1265868:SRIM RS36160
gene id: 1265868:SRIM_RS36160
uniprot id: L8ETT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS31165
gene id: 1265868:SRIM_RS31165
uniprot id: L8EFW7
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1265868:SRIM RS01925
gene id: 1265868:SRIM_RS01925
uniprot id: L8ENK6
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS05385
gene id: 1265868:SRIM_RS05385
uniprot id: L8EGQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1265868:SRIM RS14815
gene id: 1265868:SRIM_RS14815
uniprot id: L8ES80
names: Similarity
messages: Belongs to the universal stress protein A family.

1265868:SRIM RS24525
gene id: 1265868:SRIM_RS24525
uniprot id: L8EUU8
names: Similarity
messages: Belongs to the asparagine synthetase family.

1265868:SRIM RS38170
gene id: 1265868:SRIM_RS38170
uniprot id: A0A8A1V384
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1265868:SRIM RS15935
gene id: 1265868:SRIM_RS15935
uniprot id: L8EK90
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1265868:SRIM RS11165
gene id: 1265868:SRIM_RS11165
uniprot id: L8ERQ4
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS31960
gene id: 1265868:SRIM_RS31960
uniprot id: L8EUI6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1265868:SRIM RS15425
gene id: 1265868:SRIM_RS15425
uniprot id: A0A8A1UPG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

1265868:SRIM RS29280
gene id: 1265868:SRIM_RS29280
uniprot id: L8EFP0
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1265868:SRIM RS31020
gene id: 1265868:SRIM_RS31020
uniprot id: L8EUC3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1265868:SRIM RS12470
gene id: 1265868:SRIM_RS12470
uniprot id: L8ELD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1265868:SRIM RS39370
gene id: 1265868:SRIM_RS39370
uniprot id: L8F048
names: Similarity
messages: Belongs to the cytochrome P450 family.

1265868:SRIM RS18665
gene id: 1265868:SRIM_RS18665
uniprot id: L8EXL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1265868:SRIM RS12800
gene id: 1265868:SRIM_RS12800
uniprot id: L8EZ53
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1265868:SRIM RS27510
gene id: 1265868:SRIM_RS27510
uniprot id: L8ESB5
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1265868:SRIM RS16420
gene id: 1265868:SRIM_RS16420
uniprot id: L8EKV8
names: Similarity
messages: Belongs to the CFA/CMAS family.

1265868:SRIM RS12295
gene id: 1265868:SRIM_RS12295
uniprot id: L8EPT9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1265868:SRIM RS38805
gene id: 1265868:SRIM_RS38805
uniprot id: L8ESJ8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS02820
gene id: 1265868:SRIM_RS02820
uniprot id: L8EUJ7
names: Similarity
messages: Belongs to the peptidase S8 family.

1265868:SRIM RS35000
gene id: 1265868:SRIM_RS35000
uniprot id: L8ET52
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1265868:SRIM RS03555
gene id: 1265868:SRIM_RS03555
uniprot id: L8ENE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS17025
gene id: 1265868:SRIM_RS17025
uniprot id: L8EYN7
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS18445
gene id: 1265868:SRIM_RS18445
uniprot id: L8EKN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1265868:SRIM RS15155
gene id: 1265868:SRIM_RS15155
uniprot id: A0A8A1V376
names: Similarity
messages: Belongs to the UPF0303 family.

1265868:SRIM RS39905
gene id: 1265868:SRIM_RS39905
uniprot id: L8EY08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1265868:SRIM RS12885
gene id: 1265868:SRIM_RS12885
uniprot id: L8F288
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1265868:SRIM RS13605
gene id: 1265868:SRIM_RS13605
uniprot id: A0A8A1UJZ2
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

1265868:SRIM RS08535
gene id: 1265868:SRIM_RS08535
uniprot id: A0A8A1UIA9
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1265868:SRIM RS10200
gene id: 1265868:SRIM_RS10200
uniprot id: L8ELX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1265868:SRIM RS10485
gene id: 1265868:SRIM_RS10485
uniprot id: L8EJ51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell membrane
messages: Essential cell division protein.

1265868:SRIM RS29735
gene id: 1265868:SRIM_RS29735
uniprot id: L8F0Z6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1265868:SRIM RS07445
gene id: 1265868:SRIM_RS07445
uniprot id: A0A8A1UJA8
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1265868:SRIM RS20605
gene id: 1265868:SRIM_RS20605
uniprot id: L8EWQ2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1265868:SRIM RS05015
gene id: 1265868:SRIM_RS05015
uniprot id: L8EDA0
names: Similarity
messages: Belongs to the 3-hydroxybenzoate 6-hydroxylase family.

1265868:SRIM RS33045
gene id: 1265868:SRIM_RS33045
uniprot id: L8EPD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1265868:SRIM RS01500
gene id: 1265868:SRIM_RS01500
uniprot id: A0A8A1UJZ5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1265868:SRIM RS06580
gene id: 1265868:SRIM_RS06580
uniprot id: L8EE14
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1265868:SRIM RS01735
gene id: 1265868:SRIM_RS01735
uniprot id: L8EW81
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An FAD-requiring monooxygenase active on some tetracycline antibiotic derivatives, which leads to their inactivation. Hydroxylates carbon 11a of tetracycline and some analogs.
messages: Belongs to the aromatic-ring hydroxylase family. TetX subfamily.
messages: Consists of an N-terminal FAD-binding domain with a Rossman fold and a C-terminal substrate-binding domain.
messages: Cytoplasm
messages: Monomer.

1265868:SRIM RS32820
gene id: 1265868:SRIM_RS32820
uniprot id: L8ENU2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1265868:SRIM RS07420
gene id: 1265868:SRIM_RS07420
uniprot id: A0A8A1V544
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1265868:SRIM RS19115
gene id: 1265868:SRIM_RS19115
uniprot id: A0A8A1V5M5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1265868:SRIM RS34105
gene id: 1265868:SRIM_RS34105
uniprot id: L8EMY0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1265868:SRIM RS25745
gene id: 1265868:SRIM_RS25745
uniprot id: L8EPD2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1265868:SRIM RS12380
gene id: 1265868:SRIM_RS12380
uniprot id: L8EP18
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1265868:SRIM RS30835
gene id: 1265868:SRIM_RS30835
uniprot id: L8ESA1
names: Subcellular Location Annotation
messages: Cytoplasm

1265868:SRIM RS13650
gene id: 1265868:SRIM_RS13650
uniprot id: L8EK53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1265868:SRIM RS21210
gene id: 1265868:SRIM_RS21210
uniprot id: L8F1K8
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS18035
gene id: 1265868:SRIM_RS18035
uniprot id: L8EST4
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS42435
gene id: 1265868:SRIM_RS42435
uniprot id: L8EFM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1265868:SRIM RS10795
gene id: 1265868:SRIM_RS10795
uniprot id: A0A8A1V1F2
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS06760
gene id: 1265868:SRIM_RS06760
uniprot id: L8EPS7
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1265868:SRIM RS35485
gene id: 1265868:SRIM_RS35485
uniprot id: L8EES7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1265868:SRIM RS29680
gene id: 1265868:SRIM_RS29680
uniprot id: A0A8A1UT50
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1265868:SRIM RS20070
gene id: 1265868:SRIM_RS20070
uniprot id: L8EHD1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1265868:SRIM RS09085
gene id: 1265868:SRIM_RS09085
uniprot id: L8EG96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1265868:SRIM RS30695
gene id: 1265868:SRIM_RS30695
uniprot id: L8EMB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1265868:SRIM RS05740
gene id: 1265868:SRIM_RS05740
uniprot id: L8ESF9
names: Similarity
messages: Belongs to the peptidase S45 family.

1265868:SRIM RS09745
gene id: 1265868:SRIM_RS09745
uniprot id: L8EIF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1265868:SRIM RS09605
gene id: 1265868:SRIM_RS09605
uniprot id: L8EG06
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS26645
gene id: 1265868:SRIM_RS26645
uniprot id: L8EPD6
names: Subcellular Location Annotation
messages: Cytoplasm

1265868:SRIM RS22660
gene id: 1265868:SRIM_RS22660
uniprot id: L8EMV7
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1265868:SRIM RS35075
gene id: 1265868:SRIM_RS35075
uniprot id: L8ETX2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1265868:SRIM RS13665
gene id: 1265868:SRIM_RS13665
uniprot id: L8EKA1
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1265868:SRIM RS07845
gene id: 1265868:SRIM_RS07845
uniprot id: L8ESW0
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS14810
gene id: 1265868:SRIM_RS14810
uniprot id: L8EN71
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1265868:SRIM RS28330
gene id: 1265868:SRIM_RS28330
uniprot id: L8ETU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1265868:SRIM RS33485
gene id: 1265868:SRIM_RS33485
uniprot id: L8ERU6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1265868:SRIM RS09750
gene id: 1265868:SRIM_RS09750
uniprot id: L8EJG7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1265868:SRIM RS08985
gene id: 1265868:SRIM_RS08985
uniprot id: L8EHF0
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1265868:SRIM RS20295
gene id: 1265868:SRIM_RS20295
uniprot id: L8EXM0
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1265868:SRIM RS26540
gene id: 1265868:SRIM_RS26540
uniprot id: L8ETR5
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS27105
gene id: 1265868:SRIM_RS27105
uniprot id: L8EJ26
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1265868:SRIM RS08990
gene id: 1265868:SRIM_RS08990
uniprot id: L8EDR7
names: Subcellular Location Annotation
messages: Membrane

1265868:SRIM RS03265
gene id: 1265868:SRIM_RS03265
uniprot id: L8EJ81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

1265868:SRIM RS34565
gene id: 1265868:SRIM_RS34565
uniprot id: L8EMT6
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1265868:SRIM RS41375
gene id: 1265868:SRIM_RS41375
uniprot id: A0A8A1V549
names: Similarity
messages: Belongs to the cytochrome P450 family.

1265868:SRIM RS24155
gene id: 1265868:SRIM_RS24155
uniprot id: L8ENT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1265868:SRIM RS23000
gene id: 1265868:SRIM_RS23000
uniprot id: L8ET35
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1265868:SRIM RS12970
gene id: 1265868:SRIM_RS12970
uniprot id: L8EYJ5
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1265868:SRIM RS10855
gene id: 1265868:SRIM_RS10855
uniprot id: L8EQS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1265868:SRIM RS38990
gene id: 1265868:SRIM_RS38990
uniprot id: L8EVN6
names: Similarity
messages: Belongs to the thioesterase family.

1265868:SRIM RS06795
gene id: 1265868:SRIM_RS06795
uniprot id: L8EJ71
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1265868:SRIM RS32160
gene id: 1265868:SRIM_RS32160
uniprot id: L8EGM1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1265868:SRIM RS29535
gene id: 1265868:SRIM_RS29535
uniprot id: L8EKB1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1265868:SRIM RS02745
gene id: 1265868:SRIM_RS02745
uniprot id: L8EUI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.
messages: Mitochondrion

1265868:SRIM RS02205
gene id: 1265868:SRIM_RS02205
uniprot id: L8F031
names: Similarity
messages: Belongs to the barstar family.

1265868:SRIM RS08840
gene id: 1265868:SRIM_RS08840
uniprot id: L8EIR6
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1265868:SRIM RS13480
gene id: 1265868:SRIM_RS13480
uniprot id: L8EWE4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1265868:SRIM RS29705
gene id: 1265868:SRIM_RS29705
uniprot id: L8EYD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.