1255043:TVNIR RS09980
gene id: 1255043:TVNIR_RS09980
uniprot id: L0DW12
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1255043:TVNIR RS13115
gene id: 1255043:TVNIR_RS13115
uniprot id: L0E1B6
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1255043:TVNIR RS07055
gene id: 1255043:TVNIR_RS07055
uniprot id: L0DXS0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1255043:TVNIR RS13195
gene id: 1255043:TVNIR_RS13195
uniprot id: L0E1D1
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1255043:TVNIR RS16505
gene id: 1255043:TVNIR_RS16505
uniprot id: L0E1N5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1255043:TVNIR RS09650
gene id: 1255043:TVNIR_RS09650
uniprot id: L0DXH9
names: Similarity
messages: Belongs to the peptidase A31 family.

1255043:TVNIR RS08430
gene id: 1255043:TVNIR_RS08430
uniprot id: L0DYM8
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1255043:TVNIR RS07440
gene id: 1255043:TVNIR_RS07440
uniprot id: L0DW42
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1255043:TVNIR RS05710
gene id: 1255043:TVNIR_RS05710
uniprot id: L0DTI7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1255043:TVNIR RS13160
gene id: 1255043:TVNIR_RS13160
uniprot id: L0DXW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1255043:TVNIR RS11440
gene id: 1255043:TVNIR_RS11440
uniprot id: L0DYI9
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

1255043:TVNIR RS15390
gene id: 1255043:TVNIR_RS15390
uniprot id: L0E0U0
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

1255043:TVNIR RS04550
gene id: 1255043:TVNIR_RS04550
uniprot id: L0DUI7
names: Cofactor
names: Function
messages: Binds 4 [4Fe-4S] clusters per subunit.
messages: The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.

1255043:TVNIR RS08155
gene id: 1255043:TVNIR_RS08155
uniprot id: L0DYP6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1255043:TVNIR RS07395
gene id: 1255043:TVNIR_RS07395
uniprot id: L0DUG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell inner membrane
messages: Cytoplasm

1255043:TVNIR RS11140
gene id: 1255043:TVNIR_RS11140
uniprot id: L0DY86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1255043:TVNIR RS13045
gene id: 1255043:TVNIR_RS13045
uniprot id: L0DZI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1255043:TVNIR RS16685
gene id: 1255043:TVNIR_RS16685
uniprot id: L0E1H8
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1255043:TVNIR RS14915
gene id: 1255043:TVNIR_RS14915
uniprot id: L0E0Q0
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

1255043:TVNIR RS16075
gene id: 1255043:TVNIR_RS16075
uniprot id: L0E325
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1255043:TVNIR RS08935
gene id: 1255043:TVNIR_RS08935
uniprot id: L0DYX3
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS02365
gene id: 1255043:TVNIR_RS02365
uniprot id: L0DT85
names: Similarity
messages: Belongs to the HepT RNase toxin family.

1255043:TVNIR RS17600
gene id: 1255043:TVNIR_RS17600
uniprot id: L0E0I2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1255043:TVNIR RS14175
gene id: 1255043:TVNIR_RS14175
uniprot id: L0E0A5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

1255043:TVNIR RS06430
gene id: 1255043:TVNIR_RS06430
uniprot id: L0DXF9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1255043:TVNIR RS12320
gene id: 1255043:TVNIR_RS12320
uniprot id: L0DYX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

1255043:TVNIR RS02675
gene id: 1255043:TVNIR_RS02675
uniprot id: L0DTF6
names: Similarity
messages: Belongs to the UPF0178 family.

1255043:TVNIR RS03875
gene id: 1255043:TVNIR_RS03875
uniprot id: L0DU26
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1255043:TVNIR RS04170
gene id: 1255043:TVNIR_RS04170
uniprot id: L0DSJ5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1255043:TVNIR RS09570
gene id: 1255043:TVNIR_RS09570
uniprot id: L0DXB8
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.

1255043:TVNIR RS06800
gene id: 1255043:TVNIR_RS06800
uniprot id: L0DVQ5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1255043:TVNIR RS01915
gene id: 1255043:TVNIR_RS01915
uniprot id: L0DSY1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1255043:TVNIR RS18010
gene id: 1255043:TVNIR_RS18010
uniprot id: L0E2J9
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

1255043:TVNIR RS09395
gene id: 1255043:TVNIR_RS09395
uniprot id: L0DXG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

1255043:TVNIR RS09365
gene id: 1255043:TVNIR_RS09365
uniprot id: L0DVL7
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1255043:TVNIR RS04100
gene id: 1255043:TVNIR_RS04100
uniprot id: L0DU96
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1255043:TVNIR RS14085
gene id: 1255043:TVNIR_RS14085
uniprot id: L0E1V8
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

1255043:TVNIR RS09920
gene id: 1255043:TVNIR_RS09920
uniprot id: L0DVZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1255043:TVNIR RS14580
gene id: 1255043:TVNIR_RS14580
uniprot id: L0E0F4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

1255043:TVNIR RS02275
gene id: 1255043:TVNIR_RS02275
uniprot id: L0DV06
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS08910
gene id: 1255043:TVNIR_RS08910
uniprot id: L0DX23
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1255043:TVNIR RS03980
gene id: 1255043:TVNIR_RS03980
uniprot id: L0DU71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

1255043:TVNIR RS13205
gene id: 1255043:TVNIR_RS13205
uniprot id: L0DZL2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1255043:TVNIR RS16415
gene id: 1255043:TVNIR_RS16415
uniprot id: L0E387
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

1255043:TVNIR RS12475
gene id: 1255043:TVNIR_RS12475
uniprot id: L0DXG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

1255043:TVNIR RS14825
gene id: 1255043:TVNIR_RS14825
uniprot id: L0E295
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS13515
gene id: 1255043:TVNIR_RS13515
uniprot id: L0DZW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1255043:TVNIR RS04475
gene id: 1255043:TVNIR_RS04475
uniprot id: L0DSQ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Cell membrane
messages: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1255043:TVNIR RS14920
gene id: 1255043:TVNIR_RS14920
uniprot id: L0E2B4
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

1255043:TVNIR RS15240
gene id: 1255043:TVNIR_RS15240
uniprot id: L0E0Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1255043:TVNIR RS04125
gene id: 1255043:TVNIR_RS04125
uniprot id: L0DUA0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1255043:TVNIR RS12130
gene id: 1255043:TVNIR_RS12130
uniprot id: L0DZ23
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1255043:TVNIR RS16045
gene id: 1255043:TVNIR_RS16045
uniprot id: L0DZK5
names: Similarity
messages: Belongs to the ArsC family.

1255043:TVNIR RS11100
gene id: 1255043:TVNIR_RS11100
uniprot id: L0DYG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1255043:TVNIR RS07675
gene id: 1255043:TVNIR_RS07675
uniprot id: L0DY38
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

1255043:TVNIR RS15950
gene id: 1255043:TVNIR_RS15950
uniprot id: L0DZI6
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1255043:TVNIR RS14660
gene id: 1255043:TVNIR_RS14660
uniprot id: L0E0K3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1255043:TVNIR RS01820
gene id: 1255043:TVNIR_RS01820
uniprot id: L0DSV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1255043:TVNIR RS02440
gene id: 1255043:TVNIR_RS02440
uniprot id: L0DTB1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1255043:TVNIR RS09735
gene id: 1255043:TVNIR_RS09735
uniprot id: L0DZB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1255043:TVNIR RS14890
gene id: 1255043:TVNIR_RS14890
uniprot id: L0E0P7
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1255043:TVNIR RS17630
gene id: 1255043:TVNIR_RS17630
uniprot id: L0E2A1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1255043:TVNIR RS12555
gene id: 1255043:TVNIR_RS12555
uniprot id: L0DXH6
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

1255043:TVNIR RS01045
gene id: 1255043:TVNIR_RS01045
uniprot id: L0DSG6
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1255043:TVNIR RS09175
gene id: 1255043:TVNIR_RS09175
uniprot id: L0DX77
names: Subunit
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.

1255043:TVNIR RS16025
gene id: 1255043:TVNIR_RS16025
uniprot id: L0E315
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1255043:TVNIR RS11105
gene id: 1255043:TVNIR_RS11105
uniprot id: L0E052
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1255043:TVNIR RS14905
gene id: 1255043:TVNIR_RS14905
uniprot id: L0E0H8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

1255043:TVNIR RS04630
gene id: 1255043:TVNIR_RS04630
uniprot id: L0DWD7
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1255043:TVNIR RS01265
gene id: 1255043:TVNIR_RS01265
uniprot id: L0DSM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

1255043:TVNIR RS06860
gene id: 1255043:TVNIR_RS06860
uniprot id: L0DVX6
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated Csm2 family.
messages: This subunit may be involved in monitoring complementarity of crRNA and target RNA.

1255043:TVNIR RS14895
gene id: 1255043:TVNIR_RS14895
uniprot id: L0E2A7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1255043:TVNIR RS03885
gene id: 1255043:TVNIR_RS03885
uniprot id: L0DU52
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

1255043:TVNIR RS09280
gene id: 1255043:TVNIR_RS09280
uniprot id: L0DX59
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1255043:TVNIR RS16170
gene id: 1255043:TVNIR_RS16170
uniprot id: L0E1H3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SoxA family.
messages: Heterodimer of SoxA and SoxX.
messages: Periplasm

1255043:TVNIR RS14820
gene id: 1255043:TVNIR_RS14820
uniprot id: L0E0M9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1255043:TVNIR RS13620
gene id: 1255043:TVNIR_RS13620
uniprot id: L0DY41
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

1255043:TVNIR RS03490
gene id: 1255043:TVNIR_RS03490
uniprot id: L0DVT6
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1255043:TVNIR RS06865
gene id: 1255043:TVNIR_RS06865
uniprot id: L0DXN7
names: Similarity
messages: Belongs to the CRISPR-associated Csm3 family.

1255043:TVNIR RS20970
gene id: 1255043:TVNIR_RS20970
uniprot id: L0DWP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

1255043:TVNIR RS12730
gene id: 1255043:TVNIR_RS12730
uniprot id: L0DZD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

1255043:TVNIR RS08650
gene id: 1255043:TVNIR_RS08650
uniprot id: L0DYS0
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1255043:TVNIR RS04665
gene id: 1255043:TVNIR_RS04665
uniprot id: L0DUM0
names: Similarity
messages: Belongs to the TPP enzyme family.

1255043:TVNIR RS12140
gene id: 1255043:TVNIR_RS12140
uniprot id: L0DYY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1255043:TVNIR RS14700
gene id: 1255043:TVNIR_RS14700
uniprot id: L0E0I0
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS09675
gene id: 1255043:TVNIR_RS09675
uniprot id: L0DXI5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Cell membrane
messages: Heterodimer of a large and a small subunit.

1255043:TVNIR RS18035
gene id: 1255043:TVNIR_RS18035
uniprot id: L0E2K6
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.

1255043:TVNIR RS11765
gene id: 1255043:TVNIR_RS11765
uniprot id: L0E0H7
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS16845
gene id: 1255043:TVNIR_RS16845
uniprot id: L0E1R2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1255043:TVNIR RS01065
gene id: 1255043:TVNIR_RS01065
uniprot id: L0DUC4
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1255043:TVNIR RS08895
gene id: 1255043:TVNIR_RS08895
uniprot id: L0DVC2
names: Subcellular Location Annotation
messages: Cytoplasm

1255043:TVNIR RS00500
gene id: 1255043:TVNIR_RS00500
uniprot id: L0DS50
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

1255043:TVNIR RS11885
gene id: 1255043:TVNIR_RS11885
uniprot id: L0E0J7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

1255043:TVNIR RS09225
gene id: 1255043:TVNIR_RS09225
uniprot id: L0DX88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1255043:TVNIR RS13840
gene id: 1255043:TVNIR_RS13840
uniprot id: L0DY89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1255043:TVNIR RS16190
gene id: 1255043:TVNIR_RS16190
uniprot id: L0DZN8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1255043:TVNIR RS04845
gene id: 1255043:TVNIR_RS04845
uniprot id: L0DSZ1
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1255043:TVNIR RS14740
gene id: 1255043:TVNIR_RS14740
uniprot id: L0E0L5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1255043:TVNIR RS07460
gene id: 1255043:TVNIR_RS07460
uniprot id: L0DW61
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1255043:TVNIR RS11220
gene id: 1255043:TVNIR_RS11220
uniprot id: L0DYI6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1255043:TVNIR RS07895
gene id: 1255043:TVNIR_RS07895
uniprot id: L0DWI7
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1255043:TVNIR RS16535
gene id: 1255043:TVNIR_RS16535
uniprot id: L0E3B1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1255043:TVNIR RS02175
gene id: 1255043:TVNIR_RS02175
uniprot id: L0DT60
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1255043:TVNIR RS18060
gene id: 1255043:TVNIR_RS18060
uniprot id: L0E2L0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1255043:TVNIR RS10370
gene id: 1255043:TVNIR_RS10370
uniprot id: L0DWB4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

1255043:TVNIR RS17785
gene id: 1255043:TVNIR_RS17785
uniprot id: L0E2C0
names: Similarity
messages: Belongs to the asparagine synthetase family.

1255043:TVNIR RS17135
gene id: 1255043:TVNIR_RS17135
uniprot id: L0E078
names: Similarity
messages: Belongs to the sulfate adenylyltransferase family.

1255043:TVNIR RS10735
gene id: 1255043:TVNIR_RS10735
uniprot id: L0DWG8
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1255043:TVNIR RS05550
gene id: 1255043:TVNIR_RS05550
uniprot id: L0DWZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1255043:TVNIR RS02970
gene id: 1255043:TVNIR_RS02970
uniprot id: L0DRX5
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1255043:TVNIR RS16325
gene id: 1255043:TVNIR_RS16325
uniprot id: L0E367
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

1255043:TVNIR RS14730
gene id: 1255043:TVNIR_RS14730
uniprot id: L0E0E0
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1255043:TVNIR RS07825
gene id: 1255043:TVNIR_RS07825
uniprot id: L0DY77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MenH family.
messages: Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
messages: Monomer.

1255043:TVNIR RS07595
gene id: 1255043:TVNIR_RS07595
uniprot id: L0DWC6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1255043:TVNIR RS15315
gene id: 1255043:TVNIR_RS15315
uniprot id: L0E0S9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1255043:TVNIR RS12055
gene id: 1255043:TVNIR_RS12055
uniprot id: L0DZ07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1255043:TVNIR RS02200
gene id: 1255043:TVNIR_RS02200
uniprot id: L0DT64
names: Similarity
messages: Belongs to the CutA family.

1255043:TVNIR RS00680
gene id: 1255043:TVNIR_RS00680
uniprot id: L0DS90
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1255043:TVNIR RS04995
gene id: 1255043:TVNIR_RS04995
uniprot id: L0DUU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

1255043:TVNIR RS11475
gene id: 1255043:TVNIR_RS11475
uniprot id: L0DWV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1255043:TVNIR RS17810
gene id: 1255043:TVNIR_RS17810
uniprot id: L0E283
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1255043:TVNIR RS11150
gene id: 1255043:TVNIR_RS11150
uniprot id: L0DYH0
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS14505
gene id: 1255043:TVNIR_RS14505
uniprot id: L0DYN7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1255043:TVNIR RS14675
gene id: 1255043:TVNIR_RS14675
uniprot id: L0E0C9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1255043:TVNIR RS13055
gene id: 1255043:TVNIR_RS13055
uniprot id: L0DZN1
names: Similarity
messages: Belongs to the CopC family.

1255043:TVNIR RS16180
gene id: 1255043:TVNIR_RS16180
uniprot id: L0E1D2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1255043:TVNIR RS15120
gene id: 1255043:TVNIR_RS15120
uniprot id: L0E0Q3
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS16160
gene id: 1255043:TVNIR_RS16160
uniprot id: L0E173
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

1255043:TVNIR RS18145
gene id: 1255043:TVNIR_RS18145
uniprot id: L0E2D6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1255043:TVNIR RS01565
gene id: 1255043:TVNIR_RS01565
uniprot id: L0DSS5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1255043:TVNIR RS09615
gene id: 1255043:TVNIR_RS09615
uniprot id: L0DVS4
names: Function
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.

1255043:TVNIR RS02385
gene id: 1255043:TVNIR_RS02385
uniprot id: L0DV27
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1255043:TVNIR RS14245
gene id: 1255043:TVNIR_RS14245
uniprot id: L0DYH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

1255043:TVNIR RS03910
gene id: 1255043:TVNIR_RS03910
uniprot id: L0DU58
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1255043:TVNIR RS12420
gene id: 1255043:TVNIR_RS12420
uniprot id: L0DYZ2
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1255043:TVNIR RS14410
gene id: 1255043:TVNIR_RS14410
uniprot id: L0DYL5
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1255043:TVNIR RS17980
gene id: 1255043:TVNIR_RS17980
uniprot id: L0E2B0
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

1255043:TVNIR RS18025
gene id: 1255043:TVNIR_RS18025
uniprot id: L0E2B7
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS12705
gene id: 1255043:TVNIR_RS12705
uniprot id: L0DXL1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1255043:TVNIR RS00425
gene id: 1255043:TVNIR_RS00425
uniprot id: L0DQN6
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS06105
gene id: 1255043:TVNIR_RS06105
uniprot id: L0DVD1
names: Similarity
messages: Belongs to the MEMO1 family.

1255043:TVNIR RS06660
gene id: 1255043:TVNIR_RS06660
uniprot id: L0DU19
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1255043:TVNIR RS12990
gene id: 1255043:TVNIR_RS12990
uniprot id: L0E195
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1255043:TVNIR RS13590
gene id: 1255043:TVNIR_RS13590
uniprot id: L0DZT7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1255043:TVNIR RS11525
gene id: 1255043:TVNIR_RS11525
uniprot id: L0DYG2
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

1255043:TVNIR RS17875
gene id: 1255043:TVNIR_RS17875
uniprot id: L0E294
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1255043:TVNIR RS04835
gene id: 1255043:TVNIR_RS04835
uniprot id: L0DWH6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1255043:TVNIR RS18055
gene id: 1255043:TVNIR_RS18055
uniprot id: L0E0T4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1255043:TVNIR RS10790
gene id: 1255043:TVNIR_RS10790
uniprot id: L0DY29
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1255043:TVNIR RS14910
gene id: 1255043:TVNIR_RS14910
uniprot id: L0DYY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1255043:TVNIR RS09160
gene id: 1255043:TVNIR_RS09160
uniprot id: L0DX29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1255043:TVNIR RS06615
gene id: 1255043:TVNIR_RS06615
uniprot id: L0DU10
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

1255043:TVNIR RS17315
gene id: 1255043:TVNIR_RS17315
uniprot id: L0E209
names: Similarity
messages: Belongs to the phosphoribulokinase family.

1255043:TVNIR RS06770
gene id: 1255043:TVNIR_RS06770
uniprot id: L0DVQ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

1255043:TVNIR RS04120
gene id: 1255043:TVNIR_RS04120
uniprot id: L0DSI3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1255043:TVNIR RS06195
gene id: 1255043:TVNIR_RS06195
uniprot id: L0DVG7
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

1255043:TVNIR RS11180
gene id: 1255043:TVNIR_RS11180
uniprot id: L0E065
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1255043:TVNIR RS08745
gene id: 1255043:TVNIR_RS08745
uniprot id: L0DX30
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1255043:TVNIR RS05785
gene id: 1255043:TVNIR_RS05785
uniprot id: L0DVB8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1255043:TVNIR RS17770
gene id: 1255043:TVNIR_RS17770
uniprot id: L0E0N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

1255043:TVNIR RS14900
gene id: 1255043:TVNIR_RS14900
uniprot id: L0E0L7
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1255043:TVNIR RS12160
gene id: 1255043:TVNIR_RS12160
uniprot id: L0E0P4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1255043:TVNIR RS14260
gene id: 1255043:TVNIR_RS14260
uniprot id: L0E082
names: Similarity
messages: Belongs to the SCO1/2 family.

1255043:TVNIR RS03675
gene id: 1255043:TVNIR_RS03675
uniprot id: L0DTZ5
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1255043:TVNIR RS12675
gene id: 1255043:TVNIR_RS12675
uniprot id: L0DZ42
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1255043:TVNIR RS05545
gene id: 1255043:TVNIR_RS05545
uniprot id: L0DV68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1255043:TVNIR RS07830
gene id: 1255043:TVNIR_RS07830
uniprot id: L0DWD2
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1255043:TVNIR RS09960
gene id: 1255043:TVNIR_RS09960
uniprot id: L0DW05
names: Similarity
messages: Belongs to the UPF0234 family.

1255043:TVNIR RS06470
gene id: 1255043:TVNIR_RS06470
uniprot id: L0DVK9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

1255043:TVNIR RS16810
gene id: 1255043:TVNIR_RS16810
uniprot id: L0E1U1
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS03160
gene id: 1255043:TVNIR_RS03160
uniprot id: L0DTQ6
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1255043:TVNIR RS03815
gene id: 1255043:TVNIR_RS03815
uniprot id: L0DVZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

1255043:TVNIR RS08890
gene id: 1255043:TVNIR_RS08890
uniprot id: L0DWX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1255043:TVNIR RS13340
gene id: 1255043:TVNIR_RS13340
uniprot id: L0E1G0
names: Similarity
messages: Belongs to the HSP15 family.

1255043:TVNIR RS14560
gene id: 1255043:TVNIR_RS14560
uniprot id: L0E0A3
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1255043:TVNIR RS06520
gene id: 1255043:TVNIR_RS06520
uniprot id: L0DXH3
names: Similarity
messages: Belongs to the citrate synthase family.

1255043:TVNIR RS11890
gene id: 1255043:TVNIR_RS11890
uniprot id: L0DYT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1255043:TVNIR RS16150
gene id: 1255043:TVNIR_RS16150
uniprot id: L0E340
names: Similarity
messages: Belongs to the peptidase S49 family.

1255043:TVNIR RS05920
gene id: 1255043:TVNIR_RS05920
uniprot id: L0DV92
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1255043:TVNIR RS01405
gene id: 1255043:TVNIR_RS01405
uniprot id: L0DSN9
names: Similarity
messages: Belongs to the GSP E family.

1255043:TVNIR RS11230
gene id: 1255043:TVNIR_RS11230
uniprot id: L0DYE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1255043:TVNIR RS04605
gene id: 1255043:TVNIR_RS04605
uniprot id: L0DUJ7
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1255043:TVNIR RS17735
gene id: 1255043:TVNIR_RS17735
uniprot id: L0E2B1
names: Similarity
messages: Belongs to the LOG family.

1255043:TVNIR RS17835
gene id: 1255043:TVNIR_RS17835
uniprot id: L0E287
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

1255043:TVNIR RS01550
gene id: 1255043:TVNIR_RS01550
uniprot id: L0DR37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1255043:TVNIR RS06990
gene id: 1255043:TVNIR_RS06990
uniprot id: L0DVU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1255043:TVNIR RS01020
gene id: 1255043:TVNIR_RS01020
uniprot id: L0DSG1
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS16215
gene id: 1255043:TVNIR_RS16215
uniprot id: L0DZP2
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1255043:TVNIR RS05035
gene id: 1255043:TVNIR_RS05035
uniprot id: L0DUS2
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS10245
gene id: 1255043:TVNIR_RS10245
uniprot id: L0DW69
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

1255043:TVNIR RS09535
gene id: 1255043:TVNIR_RS09535
uniprot id: L0DXJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1255043:TVNIR RS13375
gene id: 1255043:TVNIR_RS13375
uniprot id: L0DZJ1
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1255043:TVNIR RS07540
gene id: 1255043:TVNIR_RS07540
uniprot id: L0DUJ4
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1255043:TVNIR RS11770
gene id: 1255043:TVNIR_RS11770
uniprot id: L0DYR1
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS16560
gene id: 1255043:TVNIR_RS16560
uniprot id: L0E3B6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1255043:TVNIR RS03335
gene id: 1255043:TVNIR_RS03335
uniprot id: L0DTT5
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1255043:TVNIR RS05315
gene id: 1255043:TVNIR_RS05315
uniprot id: L0DUY6
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

1255043:TVNIR RS16970
gene id: 1255043:TVNIR_RS16970
uniprot id: L0E1X6
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

1255043:TVNIR RS08665
gene id: 1255043:TVNIR_RS08665
uniprot id: L0DV72
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1255043:TVNIR RS00885
gene id: 1255043:TVNIR_RS00885
uniprot id: L0DSD4
names: Subcellular Location Annotation
messages: Mitochondrion

1255043:TVNIR RS05980
gene id: 1255043:TVNIR_RS05980
uniprot id: L0DX85
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS10405
gene id: 1255043:TVNIR_RS10405
uniprot id: L0DY51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1255043:TVNIR RS15490
gene id: 1255043:TVNIR_RS15490
uniprot id: L0E101
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1255043:TVNIR RS07185
gene id: 1255043:TVNIR_RS07185
uniprot id: L0DXU0
names: Similarity
messages: Belongs to the glutamate synthase family.

1255043:TVNIR RS08125
gene id: 1255043:TVNIR_RS08125
uniprot id: L0DWR6
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

1255043:TVNIR RS00245
gene id: 1255043:TVNIR_RS00245
uniprot id: L0DRZ3
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

1255043:TVNIR RS12080
gene id: 1255043:TVNIR_RS12080
uniprot id: L0DZ14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1255043:TVNIR RS02730
gene id: 1255043:TVNIR_RS02730
uniprot id: L0DTG5
names: Similarity
messages: Belongs to the UPF0751 family.

1255043:TVNIR RS15450
gene id: 1255043:TVNIR_RS15450
uniprot id: L0DZA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1255043:TVNIR RS00105
gene id: 1255043:TVNIR_RS00105
uniprot id: L0DRX7
names: Similarity
messages: Belongs to the UPF0175 family.
messages: Belongs to the phD/YefM antitoxin family.

1255043:TVNIR RS12170
gene id: 1255043:TVNIR_RS12170
uniprot id: L0DYU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1255043:TVNIR RS07425
gene id: 1255043:TVNIR_RS07425
uniprot id: L0DW91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1255043:TVNIR RS15040
gene id: 1255043:TVNIR_RS15040
uniprot id: L0E0P1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1255043:TVNIR RS00930
gene id: 1255043:TVNIR_RS00930
uniprot id: L0DSE2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

1255043:TVNIR RS14625
gene id: 1255043:TVNIR_RS14625
uniprot id: L0E0G5
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1255043:TVNIR RS12895
gene id: 1255043:TVNIR_RS12895
uniprot id: L0DZA4
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1255043:TVNIR RS00895
gene id: 1255043:TVNIR_RS00895
uniprot id: L0DQU1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1255043:TVNIR RS16540
gene id: 1255043:TVNIR_RS16540
uniprot id: L0E1K8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

1255043:TVNIR RS10600
gene id: 1255043:TVNIR_RS10600
uniprot id: L0DZX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1255043:TVNIR RS12510
gene id: 1255043:TVNIR_RS12510
uniprot id: L0E0V5
names: Similarity
messages: Belongs to the HPrK/P family.

1255043:TVNIR RS17100
gene id: 1255043:TVNIR_RS17100
uniprot id: L0E3K2
names: Similarity
messages: Belongs to the thioredoxin family.

1255043:TVNIR RS07635
gene id: 1255043:TVNIR_RS07635
uniprot id: L0DW85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1255043:TVNIR RS00995
gene id: 1255043:TVNIR_RS00995
uniprot id: L0DUB0
names: Similarity
messages: Belongs to the peptidase M16 family.

1255043:TVNIR RS12765
gene id: 1255043:TVNIR_RS12765
uniprot id: L0DZA6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

1255043:TVNIR RS04905
gene id: 1255043:TVNIR_RS04905
uniprot id: L0DWJ1
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

1255043:TVNIR RS11870
gene id: 1255043:TVNIR_RS11870
uniprot id: L0DYN5
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1255043:TVNIR RS15210
gene id: 1255043:TVNIR_RS15210
uniprot id: L0E0S5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1255043:TVNIR RS18210
gene id: 1255043:TVNIR_RS18210
uniprot id: L0E2J0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

1255043:TVNIR RS14365
gene id: 1255043:TVNIR_RS14365
uniprot id: L0E0E2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1255043:TVNIR RS01060
gene id: 1255043:TVNIR_RS01060
uniprot id: L0DSI4
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1255043:TVNIR RS10535
gene id: 1255043:TVNIR_RS10535
uniprot id: L0DXZ6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1255043:TVNIR RS04950
gene id: 1255043:TVNIR_RS04950
uniprot id: L0DUT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1255043:TVNIR RS03835
gene id: 1255043:TVNIR_RS03835
uniprot id: L0DU45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1255043:TVNIR RS11210
gene id: 1255043:TVNIR_RS11210
uniprot id: L0DYA3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1255043:TVNIR RS12550
gene id: 1255043:TVNIR_RS12550
uniprot id: L0DZ18
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1255043:TVNIR RS06690
gene id: 1255043:TVNIR_RS06690
uniprot id: L0DVT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1255043:TVNIR RS16475
gene id: 1255043:TVNIR_RS16475
uniprot id: L0DZT6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

1255043:TVNIR RS03745
gene id: 1255043:TVNIR_RS03745
uniprot id: L0DU11
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1255043:TVNIR RS11190
gene id: 1255043:TVNIR_RS11190
uniprot id: L0DY98
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1255043:TVNIR RS07090
gene id: 1255043:TVNIR_RS07090
uniprot id: L0DVW7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1255043:TVNIR RS01785
gene id: 1255043:TVNIR_RS01785
uniprot id: L0DUR1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1255043:TVNIR RS12880
gene id: 1255043:TVNIR_RS12880
uniprot id: L0E158
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

1255043:TVNIR RS01230
gene id: 1255043:TVNIR_RS01230
uniprot id: L0DSJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

1255043:TVNIR RS12465
gene id: 1255043:TVNIR_RS12465
uniprot id: L0DZ50
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS01665
gene id: 1255043:TVNIR_RS01665
uniprot id: L0DSU6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1255043:TVNIR RS01125
gene id: 1255043:TVNIR_RS01125
uniprot id: L0DSH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

1255043:TVNIR RS04945
gene id: 1255043:TVNIR_RS04945
uniprot id: L0DT13
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1255043:TVNIR RS11980
gene id: 1255043:TVNIR_RS11980
uniprot id: L0DYZ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1255043:TVNIR RS08020
gene id: 1255043:TVNIR_RS08020
uniprot id: L0DWH3
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS13825
gene id: 1255043:TVNIR_RS13825
uniprot id: L0E1R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

1255043:TVNIR RS06590
gene id: 1255043:TVNIR_RS06590
uniprot id: L0DVL3
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS17080
gene id: 1255043:TVNIR_RS17080
uniprot id: L0E1W1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1255043:TVNIR RS11800
gene id: 1255043:TVNIR_RS11800
uniprot id: L0DYL9
names: Similarity
messages: Belongs to the peptidase A24 family.

1255043:TVNIR RS12645
gene id: 1255043:TVNIR_RS12645
uniprot id: L0DZ37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1255043:TVNIR RS05765
gene id: 1255043:TVNIR_RS05765
uniprot id: L0DVB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: Membrane

1255043:TVNIR RS17715
gene id: 1255043:TVNIR_RS17715
uniprot id: L0E260
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

1255043:TVNIR RS03995
gene id: 1255043:TVNIR_RS03995
uniprot id: L0DU47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm

1255043:TVNIR RS06655
gene id: 1255043:TVNIR_RS06655
uniprot id: L0DVM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

1255043:TVNIR RS10125
gene id: 1255043:TVNIR_RS10125
uniprot id: L0DXP4
names: Similarity
messages: Belongs to the YkuD family.

1255043:TVNIR RS11265
gene id: 1255043:TVNIR_RS11265
uniprot id: L0DWQ4
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.

1255043:TVNIR RS00285
gene id: 1255043:TVNIR_RS00285
uniprot id: L0DTS2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1255043:TVNIR RS04380
gene id: 1255043:TVNIR_RS04380
uniprot id: L0DW92
names: Function
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

1255043:TVNIR RS14735
gene id: 1255043:TVNIR_RS14735
uniprot id: L0DYU3
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1255043:TVNIR RS00085
gene id: 1255043:TVNIR_RS00085
uniprot id: L0DRU7
names: Similarity
messages: Belongs to the HepT RNase toxin family.

1255043:TVNIR RS18150
gene id: 1255043:TVNIR_RS18150
uniprot id: L0E0U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

1255043:TVNIR RS14840
gene id: 1255043:TVNIR_RS14840
uniprot id: L0DYW6
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.
messages: Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.

1255043:TVNIR RS12470
gene id: 1255043:TVNIR_RS12470
uniprot id: L0DZ03
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1255043:TVNIR RS02965
gene id: 1255043:TVNIR_RS02965
uniprot id: L0DTK0
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

1255043:TVNIR RS07065
gene id: 1255043:TVNIR_RS07065
uniprot id: L0DVW1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1255043:TVNIR RS04025
gene id: 1255043:TVNIR_RS04025
uniprot id: L0DU79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

1255043:TVNIR RS09915
gene id: 1255043:TVNIR_RS09915
uniprot id: L0DXJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1255043:TVNIR RS05655
gene id: 1255043:TVNIR_RS05655
uniprot id: L0DV44
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1255043:TVNIR RS04385
gene id: 1255043:TVNIR_RS04385
uniprot id: L0DUE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

1255043:TVNIR RS14265
gene id: 1255043:TVNIR_RS14265
uniprot id: L0E034
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

1255043:TVNIR RS16730
gene id: 1255043:TVNIR_RS16730
uniprot id: L0E3E2
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1255043:TVNIR RS10230
gene id: 1255043:TVNIR_RS10230
uniprot id: L0DZL9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

1255043:TVNIR RS12615
gene id: 1255043:TVNIR_RS12615
uniprot id: L0E0X6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1255043:TVNIR RS14510
gene id: 1255043:TVNIR_RS14510
uniprot id: L0E0G9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1255043:TVNIR RS14695
gene id: 1255043:TVNIR_RS14695
uniprot id: L0E270
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1255043:TVNIR RS06785
gene id: 1255043:TVNIR_RS06785
uniprot id: L0DXM1
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1255043:TVNIR RS01110
gene id: 1255043:TVNIR_RS01110
uniprot id: L0DSJ3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Glycine N-methyltransferase family.

1255043:TVNIR RS05965
gene id: 1255043:TVNIR_RS05965
uniprot id: L0DVA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1255043:TVNIR RS02230
gene id: 1255043:TVNIR_RS02230
uniprot id: L0DUZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1255043:TVNIR RS03030
gene id: 1255043:TVNIR_RS03030
uniprot id: L0DTM6
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

1255043:TVNIR RS00805
gene id: 1255043:TVNIR_RS00805
uniprot id: L0DSB4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1255043:TVNIR RS06775
gene id: 1255043:TVNIR_RS06775
uniprot id: L0DU42
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

1255043:TVNIR RS08630
gene id: 1255043:TVNIR_RS08630
uniprot id: L0DWW8
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1255043:TVNIR RS15805
gene id: 1255043:TVNIR_RS15805
uniprot id: L0E156
names: Similarity
messages: Belongs to the citrate synthase family.

1255043:TVNIR RS04060
gene id: 1255043:TVNIR_RS04060
uniprot id: L0DU74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1255043:TVNIR RS18140
gene id: 1255043:TVNIR_RS18140
uniprot id: L0E2H9
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

1255043:TVNIR RS02225
gene id: 1255043:TVNIR_RS02225
uniprot id: L0DT69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1255043:TVNIR RS09925
gene id: 1255043:TVNIR_RS09925
uniprot id: L0DXS1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1255043:TVNIR RS11685
gene id: 1255043:TVNIR_RS11685
uniprot id: L0DYT4
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1255043:TVNIR RS08755
gene id: 1255043:TVNIR_RS08755
uniprot id: L0DWY9
names: Similarity
messages: Belongs to the archease family.

1255043:TVNIR RS12945
gene id: 1255043:TVNIR_RS12945
uniprot id: L0DZG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1255043:TVNIR RS05440
gene id: 1255043:TVNIR_RS05440
uniprot id: L0DUZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1255043:TVNIR RS06400
gene id: 1255043:TVNIR_RS06400
uniprot id: L0DVN3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1255043:TVNIR RS15080
gene id: 1255043:TVNIR_RS15080
uniprot id: L0DZ15
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1255043:TVNIR RS07160
gene id: 1255043:TVNIR_RS07160
uniprot id: L0DW01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1255043:TVNIR RS05685
gene id: 1255043:TVNIR_RS05685
uniprot id: L0DV96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1255043:TVNIR RS07995
gene id: 1255043:TVNIR_RS07995
uniprot id: L0DWH1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1255043:TVNIR RS10310
gene id: 1255043:TVNIR_RS10310
uniprot id: L0DXW2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1255043:TVNIR RS12310
gene id: 1255043:TVNIR_RS12310
uniprot id: L0E0R6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

1255043:TVNIR RS02005
gene id: 1255043:TVNIR_RS02005
uniprot id: L0DT15
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1255043:TVNIR RS06145
gene id: 1255043:TVNIR_RS06145
uniprot id: L0DVF8
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS02205
gene id: 1255043:TVNIR_RS02205
uniprot id: L0DUY9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1255043:TVNIR RS17545
gene id: 1255043:TVNIR_RS17545
uniprot id: L0E207
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1255043:TVNIR RS08495
gene id: 1255043:TVNIR_RS08495
uniprot id: L0DV42
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1255043:TVNIR RS11975
gene id: 1255043:TVNIR_RS11975
uniprot id: L0DX54
names: Similarity
messages: Belongs to the PhoH family.

1255043:TVNIR RS12415
gene id: 1255043:TVNIR_RS12415
uniprot id: L0DZ38
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1255043:TVNIR RS03825
gene id: 1255043:TVNIR_RS03825
uniprot id: L0DU17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

1255043:TVNIR RS07680
gene id: 1255043:TVNIR_RS07680
uniprot id: L0DWA2
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

1255043:TVNIR RS02530
gene id: 1255043:TVNIR_RS02530
uniprot id: L0DTC9
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1255043:TVNIR RS07400
gene id: 1255043:TVNIR_RS07400
uniprot id: L0DW86
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1255043:TVNIR RS15970
gene id: 1255043:TVNIR_RS15970
uniprot id: L0E139
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1255043:TVNIR RS05895
gene id: 1255043:TVNIR_RS05895
uniprot id: L0DX66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

1255043:TVNIR RS12240
gene id: 1255043:TVNIR_RS12240
uniprot id: L0DZ01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1255043:TVNIR RS05360
gene id: 1255043:TVNIR_RS05360
uniprot id: L0DV12
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1255043:TVNIR RS13150
gene id: 1255043:TVNIR_RS13150
uniprot id: L0DZK2
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1255043:TVNIR RS09180
gene id: 1255043:TVNIR_RS09180
uniprot id: L0DX35
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1255043:TVNIR RS08750
gene id: 1255043:TVNIR_RS08750
uniprot id: L0DYT8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

1255043:TVNIR RS03440
gene id: 1255043:TVNIR_RS03440
uniprot id: L0DTX7
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

1255043:TVNIR RS10590
gene id: 1255043:TVNIR_RS10590
uniprot id: L0DWF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

1255043:TVNIR RS08930
gene id: 1255043:TVNIR_RS08930
uniprot id: L0DX69
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1255043:TVNIR RS11625
gene id: 1255043:TVNIR_RS11625
uniprot id: L0DYM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1255043:TVNIR RS00170
gene id: 1255043:TVNIR_RS00170
uniprot id: L0DRX9
names: Similarity
messages: Belongs to the CcdB toxin family.

1255043:TVNIR RS00310
gene id: 1255043:TVNIR_RS00310
uniprot id: L0DTS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1255043:TVNIR RS14170
gene id: 1255043:TVNIR_RS14170
uniprot id: L0DYF8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1255043:TVNIR RS12075
gene id: 1255043:TVNIR_RS12075
uniprot id: L0DX75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1255043:TVNIR RS11155
gene id: 1255043:TVNIR_RS11155
uniprot id: L0E062
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1255043:TVNIR RS16515
gene id: 1255043:TVNIR_RS16515
uniprot id: L0E1K2
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1255043:TVNIR RS06225
gene id: 1255043:TVNIR_RS06225
uniprot id: L0DVF5
names: Similarity
messages: Belongs to the UPF0235 family.

1255043:TVNIR RS06975
gene id: 1255043:TVNIR_RS06975
uniprot id: L0DVZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1255043:TVNIR RS12780
gene id: 1255043:TVNIR_RS12780
uniprot id: L0DZE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

1255043:TVNIR RS12290
gene id: 1255043:TVNIR_RS12290
uniprot id: L0DZ11
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1255043:TVNIR RS02070
gene id: 1255043:TVNIR_RS02070
uniprot id: L0DUW0
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.

1255043:TVNIR RS12070
gene id: 1255043:TVNIR_RS12070
uniprot id: L0DYS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1255043:TVNIR RS13605
gene id: 1255043:TVNIR_RS13605
uniprot id: L0DZY3
names: Caution
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1255043:TVNIR RS01900
gene id: 1255043:TVNIR_RS01900
uniprot id: L0DR97
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1255043:TVNIR RS01290
gene id: 1255043:TVNIR_RS01290
uniprot id: L0DSM5
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

1255043:TVNIR RS18170
gene id: 1255043:TVNIR_RS18170
uniprot id: L0E2E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP M family.
messages: Cell inner membrane
messages: Membrane

1255043:TVNIR RS01105
gene id: 1255043:TVNIR_RS01105
uniprot id: L0DQV4
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1255043:TVNIR RS05615
gene id: 1255043:TVNIR_RS05615
uniprot id: L0DV83
names: Similarity
messages: Belongs to the asparagine synthetase family.

1255043:TVNIR RS01095
gene id: 1255043:TVNIR_RS01095
uniprot id: L0DSH7
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1255043:TVNIR RS15785
gene id: 1255043:TVNIR_RS15785
uniprot id: L0E102
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1255043:TVNIR RS03950
gene id: 1255043:TVNIR_RS03950
uniprot id: L0DSE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1255043:TVNIR RS10585
gene id: 1255043:TVNIR_RS10585
uniprot id: L0DY03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1255043:TVNIR RS08270
gene id: 1255043:TVNIR_RS08270
uniprot id: L0DWU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

1255043:TVNIR RS11240
gene id: 1255043:TVNIR_RS11240
uniprot id: L0DWQ0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1255043:TVNIR RS05365
gene id: 1255043:TVNIR_RS05365
uniprot id: L0DWT7
names: Similarity
messages: Belongs to the YoeB family.

1255043:TVNIR RS14665
gene id: 1255043:TVNIR_RS14665
uniprot id: L0E267
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1255043:TVNIR RS00330
gene id: 1255043:TVNIR_RS00330
uniprot id: L0DS13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1255043:TVNIR RS01400
gene id: 1255043:TVNIR_RS01400
uniprot id: L0DUI9
names: Similarity
messages: Belongs to the GSP E family.

1255043:TVNIR RS10355
gene id: 1255043:TVNIR_RS10355
uniprot id: L0DZQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1255043:TVNIR RS10330
gene id: 1255043:TVNIR_RS10330
uniprot id: L0DZN9
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1255043:TVNIR RS12720
gene id: 1255043:TVNIR_RS12720
uniprot id: L0DZ53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1255043:TVNIR RS17305
gene id: 1255043:TVNIR_RS17305
uniprot id: L0E240
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1255043:TVNIR RS00010
gene id: 1255043:TVNIR_RS00010
uniprot id: L0DTL8
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS18120
gene id: 1255043:TVNIR_RS18120
uniprot id: L0E2D2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

1255043:TVNIR RS09590
gene id: 1255043:TVNIR_RS09590
uniprot id: L0DXG4
names: Similarity
messages: Belongs to the HypE family.

1255043:TVNIR RS03590
gene id: 1255043:TVNIR_RS03590
uniprot id: L0DVV2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1255043:TVNIR RS11905
gene id: 1255043:TVNIR_RS11905
uniprot id: L0DYX9
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1255043:TVNIR RS01765
gene id: 1255043:TVNIR_RS01765
uniprot id: L0DUQ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

1255043:TVNIR RS12865
gene id: 1255043:TVNIR_RS12865
uniprot id: L0DZ92
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1255043:TVNIR RS14655
gene id: 1255043:TVNIR_RS14655
uniprot id: L0DYS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1255043:TVNIR RS06680
gene id: 1255043:TVNIR_RS06680
uniprot id: L0DVN2
names: Similarity
messages: Belongs to the YciI family.

1255043:TVNIR RS09275
gene id: 1255043:TVNIR_RS09275
uniprot id: L0DXA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1255043:TVNIR RS10435
gene id: 1255043:TVNIR_RS10435
uniprot id: L0DZU0
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1255043:TVNIR RS12425
gene id: 1255043:TVNIR_RS12425
uniprot id: L0DXE8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1255043:TVNIR RS18165
gene id: 1255043:TVNIR_RS18165
uniprot id: L0E2I3
names: Similarity
messages: Belongs to the GSP N family.

1255043:TVNIR RS17605
gene id: 1255043:TVNIR_RS17605
uniprot id: L0E296
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1255043:TVNIR RS01575
gene id: 1255043:TVNIR_RS01575
uniprot id: L0DR41
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1255043:TVNIR RS12135
gene id: 1255043:TVNIR_RS12135
uniprot id: L0E0P0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1255043:TVNIR RS15165
gene id: 1255043:TVNIR_RS15165
uniprot id: L0E0R3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1255043:TVNIR RS00385
gene id: 1255043:TVNIR_RS00385
uniprot id: L0DTU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1255043:TVNIR RS18185
gene id: 1255043:TVNIR_RS18185
uniprot id: L0E470
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

1255043:TVNIR RS11995
gene id: 1255043:TVNIR_RS11995
uniprot id: L0DYR2
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS04660
gene id: 1255043:TVNIR_RS04660
uniprot id: L0DSU7
names: Similarity
messages: Belongs to the glutamate synthase family.

1255043:TVNIR RS18225
gene id: 1255043:TVNIR_RS18225
uniprot id: L0E2N6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1255043:TVNIR RS17625
gene id: 1255043:TVNIR_RS17625
uniprot id: L0E0I7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1255043:TVNIR RS03605
gene id: 1255043:TVNIR_RS03605
uniprot id: L0DS93
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1255043:TVNIR RS15800
gene id: 1255043:TVNIR_RS15800
uniprot id: L0E2X0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

1255043:TVNIR RS11855
gene id: 1255043:TVNIR_RS11855
uniprot id: L0DYW9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1255043:TVNIR RS15085
gene id: 1255043:TVNIR_RS15085
uniprot id: L0E0S8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1255043:TVNIR RS07615
gene id: 1255043:TVNIR_RS07615
uniprot id: L0DUK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

1255043:TVNIR RS00365
gene id: 1255043:TVNIR_RS00365
uniprot id: L0DS26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1255043:TVNIR RS14785
gene id: 1255043:TVNIR_RS14785
uniprot id: L0E0F2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1255043:TVNIR RS15380
gene id: 1255043:TVNIR_RS15380
uniprot id: L0E2P8
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1255043:TVNIR RS08815
gene id: 1255043:TVNIR_RS08815
uniprot id: L0DWW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-2 integral membrane protein family. Lipooligosaccharide exporter (TC 3.A.1.102) subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex NodIJ involved in the export of the nodulation factors (Nod factors), the bacterial signal molecules that induce symbiosis and subsequent nodulation induction. Nod factors are LCO (lipo-chitin oligosaccharide), a modified beta-1,4-linked N-acetylglucosamine oligosaccharide. This subunit encodes the transporter.
messages: The complex is composed of two ATP-binding proteins (NodI) and two transmembrane proteins (NodJ).

1255043:TVNIR RS06185
gene id: 1255043:TVNIR_RS06185
uniprot id: L0DVJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapF family.
messages: Could be involved in the maturation of NapA, the catalytic subunit of the periplasmic nitrate reductase, before its export into the periplasm.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

1255043:TVNIR RS12735
gene id: 1255043:TVNIR_RS12735
uniprot id: L0E103
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

1255043:TVNIR RS12430
gene id: 1255043:TVNIR_RS12430
uniprot id: L0DZ76
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1255043:TVNIR RS18045
gene id: 1255043:TVNIR_RS18045
uniprot id: L0E2G1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1255043:TVNIR RS06065
gene id: 1255043:TVNIR_RS06065
uniprot id: L0DVG9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1255043:TVNIR RS09170
gene id: 1255043:TVNIR_RS09170
uniprot id: L0DZ17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1255043:TVNIR RS09465
gene id: 1255043:TVNIR_RS09465
uniprot id: L0DXI0
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

1255043:TVNIR RS06370
gene id: 1255043:TVNIR_RS06370
uniprot id: L0DVH9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1255043:TVNIR RS02195
gene id: 1255043:TVNIR_RS02195
uniprot id: L0DRG2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

1255043:TVNIR RS01195
gene id: 1255043:TVNIR_RS01195
uniprot id: L0DQW6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1255043:TVNIR RS09020
gene id: 1255043:TVNIR_RS09020
uniprot id: L0DVE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

1255043:TVNIR RS12295
gene id: 1255043:TVNIR_RS12295
uniprot id: L0DYW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1255043:TVNIR RS12525
gene id: 1255043:TVNIR_RS12525
uniprot id: L0DXH2
names: Subcellular Location Annotation
messages: Cytoplasm

1255043:TVNIR RS11185
gene id: 1255043:TVNIR_RS11185
uniprot id: L0DYD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1255043:TVNIR RS08680
gene id: 1255043:TVNIR_RS08680
uniprot id: L0DWX7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

1255043:TVNIR RS09655
gene id: 1255043:TVNIR_RS09655
uniprot id: L0DXE2
names: Similarity
messages: Belongs to the HupH/HyaF family.

1255043:TVNIR RS04505
gene id: 1255043:TVNIR_RS04505
uniprot id: L0DUH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1255043:TVNIR RS09555
gene id: 1255043:TVNIR_RS09555
uniprot id: L0DXJ7
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

1255043:TVNIR RS12340
gene id: 1255043:TVNIR_RS12340
uniprot id: L0DZ22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1255043:TVNIR RS06835
gene id: 1255043:TVNIR_RS06835
uniprot id: L0DVX0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1255043:TVNIR RS13810
gene id: 1255043:TVNIR_RS13810
uniprot id: L0DZT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1255043:TVNIR RS07205
gene id: 1255043:TVNIR_RS07205
uniprot id: L0DW46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1255043:TVNIR RS17945
gene id: 1255043:TVNIR_RS17945
uniprot id: L0E429
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1255043:TVNIR RS12045
gene id: 1255043:TVNIR_RS12045
uniprot id: L0DYS1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1255043:TVNIR RS01830
gene id: 1255043:TVNIR_RS01830
uniprot id: L0DSY7
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1255043:TVNIR RS16630
gene id: 1255043:TVNIR_RS16630
uniprot id: L0E1M2
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1255043:TVNIR RS12610
gene id: 1255043:TVNIR_RS12610
uniprot id: L0DZB2
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1255043:TVNIR RS00390
gene id: 1255043:TVNIR_RS00390
uniprot id: L0DS33
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1255043:TVNIR RS12275
gene id: 1255043:TVNIR_RS12275
uniprot id: L0DXB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1255043:TVNIR RS06005
gene id: 1255043:TVNIR_RS06005
uniprot id: L0DVC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm

1255043:TVNIR RS13805
gene id: 1255043:TVNIR_RS13805
uniprot id: L0DZY6
names: Similarity
messages: Belongs to the peptidase S11 family.

1255043:TVNIR RS16035
gene id: 1255043:TVNIR_RS16035
uniprot id: L0E150
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1255043:TVNIR RS04155
gene id: 1255043:TVNIR_RS04155
uniprot id: L0DW54
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

1255043:TVNIR RS09080
gene id: 1255043:TVNIR_RS09080
uniprot id: L0DZ00
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1255043:TVNIR RS05975
gene id: 1255043:TVNIR_RS05975
uniprot id: L0DVF4
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1255043:TVNIR RS06285
gene id: 1255043:TVNIR_RS06285
uniprot id: L0DVL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

1255043:TVNIR RS12050
gene id: 1255043:TVNIR_RS12050
uniprot id: L0DX70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1255043:TVNIR RS13300
gene id: 1255043:TVNIR_RS13300
uniprot id: L0DZH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

1255043:TVNIR RS11135
gene id: 1255043:TVNIR_RS11135
uniprot id: L0DYC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1255043:TVNIR RS13775
gene id: 1255043:TVNIR_RS13775
uniprot id: L0E019
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

1255043:TVNIR RS18015
gene id: 1255043:TVNIR_RS18015
uniprot id: L0E441
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

1255043:TVNIR RS01640
gene id: 1255043:TVNIR_RS01640
uniprot id: L0DUN4
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

1255043:TVNIR RS13520
gene id: 1255043:TVNIR_RS13520
uniprot id: L0E1J8
names: Similarity
messages: Belongs to the UPF0166 family.

1255043:TVNIR RS10380
gene id: 1255043:TVNIR_RS10380
uniprot id: L0DZS7
names: Similarity
messages: Belongs to the bacterial glucokinase family.

1255043:TVNIR RS17640
gene id: 1255043:TVNIR_RS17640
uniprot id: L0E272
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1255043:TVNIR RS17610
gene id: 1255043:TVNIR_RS17610
uniprot id: L0E3T8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1255043:TVNIR RS09150
gene id: 1255043:TVNIR_RS09150
uniprot id: L0DZ12
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS03860
gene id: 1255043:TVNIR_RS03860
uniprot id: L0DU49
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1255043:TVNIR RS17540
gene id: 1255043:TVNIR_RS17540
uniprot id: L0E249
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1255043:TVNIR RS16890
gene id: 1255043:TVNIR_RS16890
uniprot id: L0E1M0
names: Similarity
messages: Belongs to the Fur family.

1255043:TVNIR RS14855
gene id: 1255043:TVNIR_RS14855
uniprot id: L0E0G8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

1255043:TVNIR RS15225
gene id: 1255043:TVNIR_RS15225
uniprot id: L0E0V7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1255043:TVNIR RS03850
gene id: 1255043:TVNIR_RS03850
uniprot id: L0DU22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1255043:TVNIR RS09595
gene id: 1255043:TVNIR_RS09595
uniprot id: L0DXC6
names: Similarity
messages: Belongs to the HypD family.

1255043:TVNIR RS16480
gene id: 1255043:TVNIR_RS16480
uniprot id: L0E1N2
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

1255043:TVNIR RS14585
gene id: 1255043:TVNIR_RS14585
uniprot id: L0E0A8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

1255043:TVNIR RS01450
gene id: 1255043:TVNIR_RS01450
uniprot id: L0DUJ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1255043:TVNIR RS17955
gene id: 1255043:TVNIR_RS17955
uniprot id: L0E2A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

1255043:TVNIR RS14745
gene id: 1255043:TVNIR_RS14745
uniprot id: L0E282
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1255043:TVNIR RS12060
gene id: 1255043:TVNIR_RS12060
uniprot id: L0E0M7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1255043:TVNIR RS13820
gene id: 1255043:TVNIR_RS13820
uniprot id: L0E029
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

1255043:TVNIR RS11160
gene id: 1255043:TVNIR_RS11160
uniprot id: L0DYC8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1255043:TVNIR RS13830
gene id: 1255043:TVNIR_RS13830
uniprot id: L0DZZ3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1255043:TVNIR RS07465
gene id: 1255043:TVNIR_RS07465
uniprot id: L0DW47
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1255043:TVNIR RS00430
gene id: 1255043:TVNIR_RS00430
uniprot id: L0DS34
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS17765
gene id: 1255043:TVNIR_RS17765
uniprot id: L0E271
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

1255043:TVNIR RS02455
gene id: 1255043:TVNIR_RS02455
uniprot id: L0DTB5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1255043:TVNIR RS05530
gene id: 1255043:TVNIR_RS05530
uniprot id: L0DWY7
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1255043:TVNIR RS09255
gene id: 1255043:TVNIR_RS09255
uniprot id: L0DX52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1255043:TVNIR RS14810
gene id: 1255043:TVNIR_RS14810
uniprot id: L0E0F7
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1255043:TVNIR RS13610
gene id: 1255043:TVNIR_RS13610
uniprot id: L0E1L6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1255043:TVNIR RS10215
gene id: 1255043:TVNIR_RS10215
uniprot id: L0DXR2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

1255043:TVNIR RS17475
gene id: 1255043:TVNIR_RS17475
uniprot id: L0E236
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1255043:TVNIR RS07490
gene id: 1255043:TVNIR_RS07490
uniprot id: L0DW53
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1255043:TVNIR RS15925
gene id: 1255043:TVNIR_RS15925
uniprot id: L0DZI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1255043:TVNIR RS00900
gene id: 1255043:TVNIR_RS00900
uniprot id: L0DSF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

1255043:TVNIR RS14555
gene id: 1255043:TVNIR_RS14555
uniprot id: L0E243
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1255043:TVNIR RS15570
gene id: 1255043:TVNIR_RS15570
uniprot id: L0E0W7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1255043:TVNIR RS08525
gene id: 1255043:TVNIR_RS08525
uniprot id: L0DWZ0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1255043:TVNIR RS06160
gene id: 1255043:TVNIR_RS06160
uniprot id: L0DVI8
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

1255043:TVNIR RS01345
gene id: 1255043:TVNIR_RS01345
uniprot id: L0DQZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

1255043:TVNIR RS17830
gene id: 1255043:TVNIR_RS17830
uniprot id: L0E2C6
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1255043:TVNIR RS15930
gene id: 1255043:TVNIR_RS15930
uniprot id: L0E1C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1255043:TVNIR RS12970
gene id: 1255043:TVNIR_RS12970
uniprot id: L0DZH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1255043:TVNIR RS16085
gene id: 1255043:TVNIR_RS16085
uniprot id: L0E160
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1255043:TVNIR RS08475
gene id: 1255043:TVNIR_RS08475
uniprot id: L0DWY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

1255043:TVNIR RS15830
gene id: 1255043:TVNIR_RS15830
uniprot id: L0E161
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

1255043:TVNIR RS02025
gene id: 1255043:TVNIR_RS02025
uniprot id: L0DUV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

1255043:TVNIR RS17675
gene id: 1255043:TVNIR_RS17675
uniprot id: L0E0K0
names: Similarity
messages: Belongs to the peptidase S41A family.

1255043:TVNIR RS12570
gene id: 1255043:TVNIR_RS12570
uniprot id: L0DZ68
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1255043:TVNIR RS02135
gene id: 1255043:TVNIR_RS02135
uniprot id: L0DT46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

1255043:TVNIR RS15835
gene id: 1255043:TVNIR_RS15835
uniprot id: L0E110
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1255043:TVNIR RS00495
gene id: 1255043:TVNIR_RS00495
uniprot id: L0DQP4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1255043:TVNIR RS12325
gene id: 1255043:TVNIR_RS12325
uniprot id: L0DXC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1255043:TVNIR RS14710
gene id: 1255043:TVNIR_RS14710
uniprot id: L0DYT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1255043:TVNIR RS18075
gene id: 1255043:TVNIR_RS18075
uniprot id: L0E0T7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1255043:TVNIR RS02110
gene id: 1255043:TVNIR_RS02110
uniprot id: L0DUW9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1255043:TVNIR RS12225
gene id: 1255043:TVNIR_RS12225
uniprot id: L0DXA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

1255043:TVNIR RS15700
gene id: 1255043:TVNIR_RS15700
uniprot id: L0E0Y5
names: Similarity
messages: Belongs to the UPF0225 family.

1255043:TVNIR RS12180
gene id: 1255043:TVNIR_RS12180
uniprot id: L0DZ34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1255043:TVNIR RS13510
gene id: 1255043:TVNIR_RS13510
uniprot id: L0DY20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1255043:TVNIR RS16200
gene id: 1255043:TVNIR_RS16200
uniprot id: L0E349
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1255043:TVNIR RS08970
gene id: 1255043:TVNIR_RS08970
uniprot id: L0DVD8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1255043:TVNIR RS06845
gene id: 1255043:TVNIR_RS06845
uniprot id: L0DVT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1255043:TVNIR RS06035
gene id: 1255043:TVNIR_RS06035
uniprot id: L0DTP1
names: Similarity
messages: Belongs to the nitroreductase family. HadB/RutE subfamily.

1255043:TVNIR RS17195
gene id: 1255043:TVNIR_RS17195
uniprot id: L0E1Y7
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

1255043:TVNIR RS01835
gene id: 1255043:TVNIR_RS01835
uniprot id: L0DUS0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1255043:TVNIR RS12930
gene id: 1255043:TVNIR_RS12930
uniprot id: L0DXT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1255043:TVNIR RS14720
gene id: 1255043:TVNIR_RS14720
uniprot id: L0E275
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1255043:TVNIR RS16460
gene id: 1255043:TVNIR_RS16460
uniprot id: L0E397
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1255043:TVNIR RS13470
gene id: 1255043:TVNIR_RS13470
uniprot id: L0E1I8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1255043:TVNIR RS08485
gene id: 1255043:TVNIR_RS08485
uniprot id: L0DWT6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.

1255043:TVNIR RS13135
gene id: 1255043:TVNIR_RS13135
uniprot id: L0DXW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1255043:TVNIR RS07195
gene id: 1255043:TVNIR_RS07195
uniprot id: L0DVY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

1255043:TVNIR RS14690
gene id: 1255043:TVNIR_RS14690
uniprot id: L0E0K7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1255043:TVNIR RS10390
gene id: 1255043:TVNIR_RS10390
uniprot id: L0DXW5
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

1255043:TVNIR RS02285
gene id: 1255043:TVNIR_RS02285
uniprot id: L0DT65
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS16255
gene id: 1255043:TVNIR_RS16255
uniprot id: L0E1E9
names: Similarity
messages: Belongs to the PhoH family.

1255043:TVNIR RS00910
gene id: 1255043:TVNIR_RS00910
uniprot id: L0DSD2
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

1255043:TVNIR RS11590
gene id: 1255043:TVNIR_RS11590
uniprot id: L0DYR4
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1255043:TVNIR RS00325
gene id: 1255043:TVNIR_RS00325
uniprot id: L0DQM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1255043:TVNIR RS17570
gene id: 1255043:TVNIR_RS17570
uniprot id: L0E211
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1255043:TVNIR RS01380
gene id: 1255043:TVNIR_RS01380
uniprot id: L0DUI5
names: Similarity
messages: Belongs to the YggT family.

1255043:TVNIR RS14930
gene id: 1255043:TVNIR_RS14930
uniprot id: L0E0I4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1255043:TVNIR RS15435
gene id: 1255043:TVNIR_RS15435
uniprot id: L0E2Q6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1255043:TVNIR RS17145
gene id: 1255043:TVNIR_RS17145
uniprot id: L0E3K7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1255043:TVNIR RS12030
gene id: 1255043:TVNIR_RS12030
uniprot id: L0DZ02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1255043:TVNIR RS15230
gene id: 1255043:TVNIR_RS15230
uniprot id: L0E2I1
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

1255043:TVNIR RS12775
gene id: 1255043:TVNIR_RS12775
uniprot id: L0DXM8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

1255043:TVNIR RS04085
gene id: 1255043:TVNIR_RS04085
uniprot id: L0DU80
names: Similarity
messages: Belongs to the YfgM family.

1255043:TVNIR RS05740
gene id: 1255043:TVNIR_RS05740
uniprot id: L0DVA9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

1255043:TVNIR RS07575
gene id: 1255043:TVNIR_RS07575
uniprot id: L0DW84
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1255043:TVNIR RS00320
gene id: 1255043:TVNIR_RS00320
uniprot id: L0DRZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1255043:TVNIR RS07170
gene id: 1255043:TVNIR_RS07170
uniprot id: L0DUB8
names: Subcellular Location Annotation
messages: Cytoplasm

1255043:TVNIR RS12035
gene id: 1255043:TVNIR_RS12035
uniprot id: L0E0M2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1255043:TVNIR RS12335
gene id: 1255043:TVNIR_RS12335
uniprot id: L0E0S0
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.

1255043:TVNIR RS17350
gene id: 1255043:TVNIR_RS17350
uniprot id: L0E0C8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

1255043:TVNIR RS17845
gene id: 1255043:TVNIR_RS17845
uniprot id: L0E2G8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

1255043:TVNIR RS13175
gene id: 1255043:TVNIR_RS13175
uniprot id: L0DZK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1255043:TVNIR RS14090
gene id: 1255043:TVNIR_RS14090
uniprot id: L0E050
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

1255043:TVNIR RS08900
gene id: 1255043:TVNIR_RS08900
uniprot id: L0DX61
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1255043:TVNIR RS16090
gene id: 1255043:TVNIR_RS16090
uniprot id: L0DZL5
names: Similarity
messages: Belongs to the peptidase U62 family.

1255043:TVNIR RS09140
gene id: 1255043:TVNIR_RS09140
uniprot id: L0DVH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1255043:TVNIR RS00975
gene id: 1255043:TVNIR_RS00975
uniprot id: L0DSF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

1255043:TVNIR RS06830
gene id: 1255043:TVNIR_RS06830
uniprot id: L0DU51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1255043:TVNIR RS13985
gene id: 1255043:TVNIR_RS13985
uniprot id: L0E1U0
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

1255043:TVNIR RS02170
gene id: 1255043:TVNIR_RS02170
uniprot id: L0DRF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1255043:TVNIR RS14140
gene id: 1255043:TVNIR_RS14140
uniprot id: L0E008
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS16450
gene id: 1255043:TVNIR_RS16450
uniprot id: L0DZT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

1255043:TVNIR RS08550
gene id: 1255043:TVNIR_RS08550
uniprot id: L0DWZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1255043:TVNIR RS16880
gene id: 1255043:TVNIR_RS16880
uniprot id: L0E1V6
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1255043:TVNIR RS18180
gene id: 1255043:TVNIR_RS18180
uniprot id: L0E2M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

1255043:TVNIR RS14455
gene id: 1255043:TVNIR_RS14455
uniprot id: L0E075
names: Similarity
messages: Belongs to the CapA family.

1255043:TVNIR RS17070
gene id: 1255043:TVNIR_RS17070
uniprot id: L0E1Z7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1255043:TVNIR RS01455
gene id: 1255043:TVNIR_RS01455
uniprot id: L0DSP9
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1255043:TVNIR RS17335
gene id: 1255043:TVNIR_RS17335
uniprot id: L0E215
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1255043:TVNIR RS14965
gene id: 1255043:TVNIR_RS14965
uniprot id: L0E2C3
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1255043:TVNIR RS01580
gene id: 1255043:TVNIR_RS01580
uniprot id: L0DST7
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1255043:TVNIR RS12150
gene id: 1255043:TVNIR_RS12150
uniprot id: L0DX92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1255043:TVNIR RS18090
gene id: 1255043:TVNIR_RS18090
uniprot id: L0E454
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1255043:TVNIR RS03785
gene id: 1255043:TVNIR_RS03785
uniprot id: L0DU36
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1255043:TVNIR RS15140
gene id: 1255043:TVNIR_RS15140
uniprot id: L0E0Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1255043:TVNIR RS12125
gene id: 1255043:TVNIR_RS12125
uniprot id: L0DX86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1255043:TVNIR RS12490
gene id: 1255043:TVNIR_RS12490
uniprot id: L0DZ55
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

1255043:TVNIR RS13925
gene id: 1255043:TVNIR_RS13925
uniprot id: L0DYB2
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1255043:TVNIR RS07890
gene id: 1255043:TVNIR_RS07890
uniprot id: L0DUR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

1255043:TVNIR RS10995
gene id: 1255043:TVNIR_RS10995
uniprot id: L0DY97
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1255043:TVNIR RS04400
gene id: 1255043:TVNIR_RS04400
uniprot id: L0DUF8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1255043:TVNIR RS13600
gene id: 1255043:TVNIR_RS13600
uniprot id: L0DY37
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1255043:TVNIR RS00475
gene id: 1255043:TVNIR_RS00475
uniprot id: L0DQP2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1255043:TVNIR RS15180
gene id: 1255043:TVNIR_RS15180
uniprot id: L0E0U8
names: Similarity
messages: Belongs to the peptidase S13 family.

1255043:TVNIR RS07180
gene id: 1255043:TVNIR_RS07180
uniprot id: L0DW40
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1255043:TVNIR RS04495
gene id: 1255043:TVNIR_RS04495
uniprot id: L0DUI4
names: Similarity
messages: Belongs to the ModE family.

1255043:TVNIR RS14000
gene id: 1255043:TVNIR_RS14000
uniprot id: L0E071
names: Function
names: Similarity
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

1255043:TVNIR RS12400
gene id: 1255043:TVNIR_RS12400
uniprot id: L0DXE3
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1255043:TVNIR RS17740
gene id: 1255043:TVNIR_RS17740
uniprot id: L0E265
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1255043:TVNIR RS11385
gene id: 1255043:TVNIR_RS11385
uniprot id: L0E0A4
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

1255043:TVNIR RS16245
gene id: 1255043:TVNIR_RS16245
uniprot id: L0E1I7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1255043:TVNIR RS15050
gene id: 1255043:TVNIR_RS15050
uniprot id: L0DZ08
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1255043:TVNIR RS16210
gene id: 1255043:TVNIR_RS16210
uniprot id: L0E182
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS12585
gene id: 1255043:TVNIR_RS12585
uniprot id: L0DZA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1255043:TVNIR RS01555
gene id: 1255043:TVNIR_RS01555
uniprot id: L0DST2
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1255043:TVNIR RS12145
gene id: 1255043:TVNIR_RS12145
uniprot id: L0DYU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1255043:TVNIR RS12965
gene id: 1255043:TVNIR_RS12965
uniprot id: L0E185
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1255043:TVNIR RS01425
gene id: 1255043:TVNIR_RS01425
uniprot id: L0DUJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1255043:TVNIR RS17265
gene id: 1255043:TVNIR_RS17265
uniprot id: L0E200
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1255043:TVNIR RS15960
gene id: 1255043:TVNIR_RS15960
uniprot id: L0E302
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1255043:TVNIR RS05970
gene id: 1255043:TVNIR_RS05970
uniprot id: L0DTN0
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1255043:TVNIR RS00490
gene id: 1255043:TVNIR_RS00490
uniprot id: L0DS32
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1255043:TVNIR RS07415
gene id: 1255043:TVNIR_RS07415
uniprot id: L0DW37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1255043:TVNIR RS07590
gene id: 1255043:TVNIR_RS07590
uniprot id: L0DUK5
names: Similarity
messages: Belongs to the pirin family.

1255043:TVNIR RS08290
gene id: 1255043:TVNIR_RS08290
uniprot id: L0DV09
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1255043:TVNIR RS08045
gene id: 1255043:TVNIR_RS08045
uniprot id: L0DWH8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1255043:TVNIR RS13170
gene id: 1255043:TVNIR_RS13170
uniprot id: L0E1C6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1255043:TVNIR RS04775
gene id: 1255043:TVNIR_RS04775
uniprot id: L0DSX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1255043:TVNIR RS04350
gene id: 1255043:TVNIR_RS04350
uniprot id: L0DUE8
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1255043:TVNIR RS01590
gene id: 1255043:TVNIR_RS01590
uniprot id: L0DST0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

1255043:TVNIR RS17995
gene id: 1255043:TVNIR_RS17995
uniprot id: L0E2F2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1255043:TVNIR RS13255
gene id: 1255043:TVNIR_RS13255
uniprot id: L0DXY0
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1255043:TVNIR RS02905
gene id: 1255043:TVNIR_RS02905
uniprot id: L0DVE5
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

1255043:TVNIR RS11825
gene id: 1255043:TVNIR_RS11825
uniprot id: L0DYM5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1255043:TVNIR RS14765
gene id: 1255043:TVNIR_RS14765
uniprot id: L0DYU8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1255043:TVNIR RS15115
gene id: 1255043:TVNIR_RS15115
uniprot id: L0E2F1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1255043:TVNIR RS07155
gene id: 1255043:TVNIR_RS07155
uniprot id: L0DXT6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1255043:TVNIR RS15810
gene id: 1255043:TVNIR_RS15810
uniprot id: L0E106
names: Similarity
messages: Belongs to the PrpD family.

1255043:TVNIR RS15405
gene id: 1255043:TVNIR_RS15405
uniprot id: L0E2Q2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1255043:TVNIR RS14800
gene id: 1255043:TVNIR_RS14800
uniprot id: L0E289
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1255043:TVNIR RS17815
gene id: 1255043:TVNIR_RS17815
uniprot id: L0E0P3
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS12015
gene id: 1255043:TVNIR_RS12015
uniprot id: L0DYW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1255043:TVNIR RS17270
gene id: 1255043:TVNIR_RS17270
uniprot id: L0E1V2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1255043:TVNIR RS18240
gene id: 1255043:TVNIR_RS18240
uniprot id: L0E2F4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

1255043:TVNIR RS08240
gene id: 1255043:TVNIR_RS08240
uniprot id: L0DV01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

1255043:TVNIR RS13185
gene id: 1255043:TVNIR_RS13185
uniprot id: L0DXW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

1255043:TVNIR RS04355
gene id: 1255043:TVNIR_RS04355
uniprot id: L0DW88
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1255043:TVNIR RS18105
gene id: 1255043:TVNIR_RS18105
uniprot id: L0E0T9
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1255043:TVNIR RS03915
gene id: 1255043:TVNIR_RS03915
uniprot id: L0DW09
names: Similarity
messages: Belongs to the UPF0434 family.

1255043:TVNIR RS18275
gene id: 1255043:TVNIR_RS18275
uniprot id: L0E484
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1255043:TVNIR RS17575
gene id: 1255043:TVNIR_RS17575
uniprot id: L0E0H6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1255043:TVNIR RS11175
gene id: 1255043:TVNIR_RS11175
uniprot id: L0DYH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

1255043:TVNIR RS07215
gene id: 1255043:TVNIR_RS07215
uniprot id: L0DW10
names: Similarity
messages: Belongs to the peptidase M17 family.

1255043:TVNIR RS09270
gene id: 1255043:TVNIR_RS09270
uniprot id: L0DZ36
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1255043:TVNIR RS17620
gene id: 1255043:TVNIR_RS17620
uniprot id: L0E221
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1255043:TVNIR RS17170
gene id: 1255043:TVNIR_RS17170
uniprot id: L0E1Y2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1255043:TVNIR RS11335
gene id: 1255043:TVNIR_RS11335
uniprot id: L0DYC4
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1255043:TVNIR RS14045
gene id: 1255043:TVNIR_RS14045
uniprot id: L0DZY5
names: Similarity
messages: Belongs to the SufE family.

1255043:TVNIR RS06780
gene id: 1255043:TVNIR_RS06780
uniprot id: L0DVV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

1255043:TVNIR RS08825
gene id: 1255043:TVNIR_RS08825
uniprot id: L0DX48
names: Similarity
messages: Belongs to the RecA family.

1255043:TVNIR RS00765
gene id: 1255043:TVNIR_RS00765
uniprot id: L0DSC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1255043:TVNIR RS06810
gene id: 1255043:TVNIR_RS06810
uniprot id: L0DVW5
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1255043:TVNIR RS16495
gene id: 1255043:TVNIR_RS16495
uniprot id: L0E1E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1255043:TVNIR RS04080
gene id: 1255043:TVNIR_RS04080
uniprot id: L0DW41
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1255043:TVNIR RS15255
gene id: 1255043:TVNIR_RS15255
uniprot id: L0E2K2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1255043:TVNIR RS03330
gene id: 1255043:TVNIR_RS03330
uniprot id: L0DVQ6
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1255043:TVNIR RS10325
gene id: 1255043:TVNIR_RS10325
uniprot id: L0DY06
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1255043:TVNIR RS00625
gene id: 1255043:TVNIR_RS00625
uniprot id: L0DU08
names: Similarity
messages: Belongs to the peptidase S8 family.

1255043:TVNIR RS00440
gene id: 1255043:TVNIR_RS00440
uniprot id: L0DS44
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS09070
gene id: 1255043:TVNIR_RS09070
uniprot id: L0DVF9
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1255043:TVNIR RS10415
gene id: 1255043:TVNIR_RS10415
uniprot id: L0DY04
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1255043:TVNIR RS14650
gene id: 1255043:TVNIR_RS14650
uniprot id: L0E0C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1255043:TVNIR RS10465
gene id: 1255043:TVNIR_RS10465
uniprot id: L0DXY3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

1255043:TVNIR RS18175
gene id: 1255043:TVNIR_RS18175
uniprot id: L0E0V1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP L family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

1255043:TVNIR RS13235
gene id: 1255043:TVNIR_RS13235
uniprot id: L0DZR1
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS06120
gene id: 1255043:TVNIR_RS06120
uniprot id: L0DVF2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

1255043:TVNIR RS15195
gene id: 1255043:TVNIR_RS15195
uniprot id: L0E0N1
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS12395
gene id: 1255043:TVNIR_RS12395
uniprot id: L0DYY7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1255043:TVNIR RS01920
gene id: 1255043:TVNIR_RS01920
uniprot id: L0DRA2
names: Similarity
messages: Belongs to the Smg family.

1255043:TVNIR RS11710
gene id: 1255043:TVNIR_RS11710
uniprot id: L0DYT9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1255043:TVNIR RS07630
gene id: 1255043:TVNIR_RS07630
uniprot id: L0DW93
names: Subunit
messages: Monomer.

1255043:TVNIR RS01245
gene id: 1255043:TVNIR_RS01245
uniprot id: L0DUF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1255043:TVNIR RS00795
gene id: 1255043:TVNIR_RS00795
uniprot id: L0DU75
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1255043:TVNIR RS13490
gene id: 1255043:TVNIR_RS13490
uniprot id: L0DZV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

1255043:TVNIR RS09550
gene id: 1255043:TVNIR_RS09550
uniprot id: L0DVQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

1255043:TVNIR RS17870
gene id: 1255043:TVNIR_RS17870
uniprot id: L0E417
names: Similarity
messages: Belongs to the DEAD box helicase family.

1255043:TVNIR RS01865
gene id: 1255043:TVNIR_RS01865
uniprot id: L0DSY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

1255043:TVNIR RS13180
gene id: 1255043:TVNIR_RS13180
uniprot id: L0DZF7
names: Similarity
messages: Belongs to the thioredoxin family.

1255043:TVNIR RS10855
gene id: 1255043:TVNIR_RS10855
uniprot id: L0DWI4
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

1255043:TVNIR RS12785
gene id: 1255043:TVNIR_RS12785
uniprot id: L0E117
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1255043:TVNIR RS10500
gene id: 1255043:TVNIR_RS10500
uniprot id: L0DZV5
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1255043:TVNIR RS12300
gene id: 1255043:TVNIR_RS12300
uniprot id: L0DXC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1255043:TVNIR RS08345
gene id: 1255043:TVNIR_RS08345
uniprot id: L0DYL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiV subfamily.
messages: Forms an heterodimer with UbiU.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiU, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

1255043:TVNIR RS08875
gene id: 1255043:TVNIR_RS08875
uniprot id: L0DX56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1255043:TVNIR RS20775
gene id: 1255043:TVNIR_RS20775
uniprot id: L0DZC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

1255043:TVNIR RS02310
gene id: 1255043:TVNIR_RS02310
uniprot id: L0DRI8
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

1255043:TVNIR RS06295
gene id: 1255043:TVNIR_RS06295
uniprot id: L0DVI6
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS07375
gene id: 1255043:TVNIR_RS07375
uniprot id: L0DXX6
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1255043:TVNIR RS03890
gene id: 1255043:TVNIR_RS03890
uniprot id: L0DW07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1255043:TVNIR RS14080
gene id: 1255043:TVNIR_RS14080
uniprot id: L0E085
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

1255043:TVNIR RS12105
gene id: 1255043:TVNIR_RS12105
uniprot id: L0DZ19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1255043:TVNIR RS01260
gene id: 1255043:TVNIR_RS01260
uniprot id: L0DQX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

1255043:TVNIR RS06670
gene id: 1255043:TVNIR_RS06670
uniprot id: L0DXK1
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1255043:TVNIR RS05760
gene id: 1255043:TVNIR_RS05760
uniprot id: L0DTJ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1255043:TVNIR RS09075
gene id: 1255043:TVNIR_RS09075
uniprot id: L0DX97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1255043:TVNIR RS05900
gene id: 1255043:TVNIR_RS05900
uniprot id: L0DVA5
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

1255043:TVNIR RS16100
gene id: 1255043:TVNIR_RS16100
uniprot id: L0E330
names: Similarity
messages: Belongs to the peptidase U62 family.

1255043:TVNIR RS08685
gene id: 1255043:TVNIR_RS08685
uniprot id: L0DWT8
names: Similarity
messages: Belongs to the ArsC family.

1255043:TVNIR RS14670
gene id: 1255043:TVNIR_RS14670
uniprot id: L0E0H5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1255043:TVNIR RS17555
gene id: 1255043:TVNIR_RS17555
uniprot id: L0E286
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1255043:TVNIR RS10270
gene id: 1255043:TVNIR_RS10270
uniprot id: L0DW74
names: Similarity
messages: Belongs to the CFA/CMAS family.

1255043:TVNIR RS07150
gene id: 1255043:TVNIR_RS07150
uniprot id: L0DW35
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

1255043:TVNIR RS01775
gene id: 1255043:TVNIR_RS01775
uniprot id: L0DSV0
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

1255043:TVNIR RS03935
gene id: 1255043:TVNIR_RS03935
uniprot id: L0DW14
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

1255043:TVNIR RS04960
gene id: 1255043:TVNIR_RS04960
uniprot id: L0DUQ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1255043:TVNIR RS02885
gene id: 1255043:TVNIR_RS02885
uniprot id: L0DVD9
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1255043:TVNIR RS03760
gene id: 1255043:TVNIR_RS03760
uniprot id: L0DU33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1255043:TVNIR RS18215
gene id: 1255043:TVNIR_RS18215
uniprot id: L0E2F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane
messages: Membrane

1255043:TVNIR RS05670
gene id: 1255043:TVNIR_RS05670
uniprot id: L0DV65
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1255043:TVNIR RS04375
gene id: 1255043:TVNIR_RS04375
uniprot id: L0DUF3
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

1255043:TVNIR RS05695
gene id: 1255043:TVNIR_RS05695
uniprot id: L0DV71
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1255043:TVNIR RS13065
gene id: 1255043:TVNIR_RS13065
uniprot id: L0DZI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1255043:TVNIR RS14805
gene id: 1255043:TVNIR_RS14805
uniprot id: L0E0K1
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1255043:TVNIR RS10580
gene id: 1255043:TVNIR_RS10580
uniprot id: L0DY35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1255043:TVNIR RS16555
gene id: 1255043:TVNIR_RS16555
uniprot id: L0E1P6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1255043:TVNIR RS16195
gene id: 1255043:TVNIR_RS16195
uniprot id: L0E1H7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1255043:TVNIR RS05070
gene id: 1255043:TVNIR_RS05070
uniprot id: L0DT38
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS10525
gene id: 1255043:TVNIR_RS10525
uniprot id: L0DZW2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1255043:TVNIR RS06980
gene id: 1255043:TVNIR_RS06980
uniprot id: L0DXQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1255043:TVNIR RS09205
gene id: 1255043:TVNIR_RS09205
uniprot id: L0DX42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1255043:TVNIR RS11500
gene id: 1255043:TVNIR_RS11500
uniprot id: L0DYP6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1255043:TVNIR RS10280
gene id: 1255043:TVNIR_RS10280
uniprot id: L0DZM9
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS06230
gene id: 1255043:TVNIR_RS06230
uniprot id: L0DTS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

1255043:TVNIR RS14925
gene id: 1255043:TVNIR_RS14925
uniprot id: L0E0M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1255043:TVNIR RS07715
gene id: 1255043:TVNIR_RS07715
uniprot id: L0DUN0
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NosZ family.
messages: Binds 2 calcium ions per subunit.
messages: Binds 6 Cu cations per subunit. Each subunit contains 2 copper centers; Cu(A) (binuclear) and Cu(Z) (tetranuclear). Cu(Z) is thought to be the site of nitrous oxide reduction.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytochrome c oxidase subunit 2 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

1255043:TVNIR RS15545
gene id: 1255043:TVNIR_RS15545
uniprot id: L0E0W2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1255043:TVNIR RS03975
gene id: 1255043:TVNIR_RS03975
uniprot id: L0DSF4
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS11715
gene id: 1255043:TVNIR_RS11715
uniprot id: L0E0G7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1255043:TVNIR RS17250
gene id: 1255043:TVNIR_RS17250
uniprot id: L0E232
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS09245
gene id: 1255043:TVNIR_RS09245
uniprot id: L0DZ31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1255043:TVNIR RS17615
gene id: 1255043:TVNIR_RS17615
uniprot id: L0E266
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1255043:TVNIR RS00405
gene id: 1255043:TVNIR_RS00405
uniprot id: L0DS27
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1255043:TVNIR RS08575
gene id: 1255043:TVNIR_RS08575
uniprot id: L0DX00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1255043:TVNIR RS14715
gene id: 1255043:TVNIR_RS14715
uniprot id: L0E0L1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1255043:TVNIR RS00375
gene id: 1255043:TVNIR_RS00375
uniprot id: L0DQN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

1255043:TVNIR RS18000
gene id: 1255043:TVNIR_RS18000
uniprot id: L0E2B3
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1255043:TVNIR RS04925
gene id: 1255043:TVNIR_RS04925
uniprot id: L0DUS6
names: Similarity
messages: Belongs to the peptidase M24B family.

1255043:TVNIR RS06445
gene id: 1255043:TVNIR_RS06445
uniprot id: L0DTX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1255043:TVNIR RS11630
gene id: 1255043:TVNIR_RS11630
uniprot id: L0DYI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1255043:TVNIR RS15010
gene id: 1255043:TVNIR_RS15010
uniprot id: L0E0R7
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1255043:TVNIR RS13370
gene id: 1255043:TVNIR_RS13370
uniprot id: L0DZP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1255043:TVNIR RS14070
gene id: 1255043:TVNIR_RS14070
uniprot id: L0DZZ0
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1255043:TVNIR RS13790
gene id: 1255043:TVNIR_RS13790
uniprot id: L0DY79
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1255043:TVNIR RS00395
gene id: 1255043:TVNIR_RS00395
uniprot id: L0DS12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1255043:TVNIR RS01310
gene id: 1255043:TVNIR_RS01310
uniprot id: L0DQY2
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

1255043:TVNIR RS15445
gene id: 1255043:TVNIR_RS15445
uniprot id: L0E0U9
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1255043:TVNIR RS10645
gene id: 1255043:TVNIR_RS10645
uniprot id: L0DY11
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1255043:TVNIR RS01525
gene id: 1255043:TVNIR_RS01525
uniprot id: L0DR33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the encapsulin family. Family 1 subfamily.
messages: Encapsulin nanocompartment

1255043:TVNIR RS04625
gene id: 1255043:TVNIR_RS04625
uniprot id: L0DUL2
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

1255043:TVNIR RS03765
gene id: 1255043:TVNIR_RS03765
uniprot id: L0DVY4
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1255043:TVNIR RS17020
gene id: 1255043:TVNIR_RS17020
uniprot id: L0E051
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1255043:TVNIR RS12185
gene id: 1255043:TVNIR_RS12185
uniprot id: L0E0P8
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1255043:TVNIR RS00465
gene id: 1255043:TVNIR_RS00465
uniprot id: L0DS49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1255043:TVNIR RS07075
gene id: 1255043:TVNIR_RS07075
uniprot id: L0DW20
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1255043:TVNIR RS00150
gene id: 1255043:TVNIR_RS00150
uniprot id: L0DTP0
names: Similarity
messages: Belongs to the HepT RNase toxin family.

1255043:TVNIR RS11700
gene id: 1255043:TVNIR_RS11700
uniprot id: L0DYJ8
names: Similarity
messages: Belongs to the P(II) protein family.

1255043:TVNIR RS10085
gene id: 1255043:TVNIR_RS10085
uniprot id: L0DXN4
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

1255043:TVNIR RS06485
gene id: 1255043:TVNIR_RS06485
uniprot id: L0DVP5
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS12020
gene id: 1255043:TVNIR_RS12020
uniprot id: L0DYR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1255043:TVNIR RS01395
gene id: 1255043:TVNIR_RS01395
uniprot id: L0DSP8
names: Similarity
messages: Belongs to the GSP E family.

1255043:TVNIR RS10360
gene id: 1255043:TVNIR_RS10360
uniprot id: L0DXZ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

1255043:TVNIR RS01905
gene id: 1255043:TVNIR_RS01905
uniprot id: L0DT01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

1255043:TVNIR RS17935
gene id: 1255043:TVNIR_RS17935
uniprot id: L0E0R5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1255043:TVNIR RS01325
gene id: 1255043:TVNIR_RS01325
uniprot id: L0DSM0
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS09200
gene id: 1255043:TVNIR_RS09200
uniprot id: L0DX83
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1255043:TVNIR RS09155
gene id: 1255043:TVNIR_RS09155
uniprot id: L0DX72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1255043:TVNIR RS16070
gene id: 1255043:TVNIR_RS16070
uniprot id: L0E1F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1255043:TVNIR RS10180
gene id: 1255043:TVNIR_RS10180
uniprot id: L0DXX5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Cell membrane
messages: Heterodimer of a large and a small subunit.

1255043:TVNIR RS01635
gene id: 1255043:TVNIR_RS01635
uniprot id: L0DSU9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1255043:TVNIR RS04160
gene id: 1255043:TVNIR_RS04160
uniprot id: L0DU97
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

1255043:TVNIR RS16675
gene id: 1255043:TVNIR_RS16675
uniprot id: L0E3D4
names: Similarity
messages: Belongs to the YciI family.

1255043:TVNIR RS11480
gene id: 1255043:TVNIR_RS11480
uniprot id: L0DYP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1255043:TVNIR RS13675
gene id: 1255043:TVNIR_RS13675
uniprot id: L0E1M9
names: Function
names: Similarity
messages: Belongs to the HARP family.
messages: RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.

1255043:TVNIR RS01075
gene id: 1255043:TVNIR_RS01075
uniprot id: L0DSG2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1255043:TVNIR RS15775
gene id: 1255043:TVNIR_RS15775
uniprot id: L0E2W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1255043:TVNIR RS06420
gene id: 1255043:TVNIR_RS06420
uniprot id: L0DTW7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1255043:TVNIR RS09385
gene id: 1255043:TVNIR_RS09385
uniprot id: L0DX79
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1255043:TVNIR RS08610
gene id: 1255043:TVNIR_RS08610
uniprot id: L0DWS3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

1255043:TVNIR RS04360
gene id: 1255043:TVNIR_RS04360
uniprot id: L0DUE0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

1255043:TVNIR RS00340
gene id: 1255043:TVNIR_RS00340
uniprot id: L0DS20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1255043:TVNIR RS10190
gene id: 1255043:TVNIR_RS10190
uniprot id: L0DXT8
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

1255043:TVNIR RS01925
gene id: 1255043:TVNIR_RS01925
uniprot id: L0DT06
names: Similarity
messages: Belongs to the DprA/Smf family.

1255043:TVNIR RS17220
gene id: 1255043:TVNIR_RS17220
uniprot id: L0E1U3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

1255043:TVNIR RS07390
gene id: 1255043:TVNIR_RS07390
uniprot id: L0DW30
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1255043:TVNIR RS00130
gene id: 1255043:TVNIR_RS00130
uniprot id: L0DRY2
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1255043:TVNIR RS05705
gene id: 1255043:TVNIR_RS05705
uniprot id: L0DV53
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS01690
gene id: 1255043:TVNIR_RS01690
uniprot id: L0DSV1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

1255043:TVNIR RS01275
gene id: 1255043:TVNIR_RS01275
uniprot id: L0DSL1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1255043:TVNIR RS10425
gene id: 1255043:TVNIR_RS10425
uniprot id: L0DWC1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1255043:TVNIR RS14475
gene id: 1255043:TVNIR_RS14475
uniprot id: L0E081
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1255043:TVNIR RS16985
gene id: 1255043:TVNIR_RS16985
uniprot id: L0E1P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

1255043:TVNIR RS12875
gene id: 1255043:TVNIR_RS12875
uniprot id: L0DZI5
names: Similarity
messages: Belongs to the RecJ family.

1255043:TVNIR RS13200
gene id: 1255043:TVNIR_RS13200
uniprot id: L0DZG3
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS07190
gene id: 1255043:TVNIR_RS07190
uniprot id: L0DW04
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1255043:TVNIR RS17210
gene id: 1255043:TVNIR_RS17210
uniprot id: L0E223
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1255043:TVNIR RS00800
gene id: 1255043:TVNIR_RS00800
uniprot id: L0DSC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1255043:TVNIR RS15360
gene id: 1255043:TVNIR_RS15360
uniprot id: L0E0Y0
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1255043:TVNIR RS06410
gene id: 1255043:TVNIR_RS06410
uniprot id: L0DVK2
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1255043:TVNIR RS17330
gene id: 1255043:TVNIR_RS17330
uniprot id: L0E3N9
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1255043:TVNIR RS12110
gene id: 1255043:TVNIR_RS12110
uniprot id: L0E0N4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1255043:TVNIR RS03360
gene id: 1255043:TVNIR_RS03360
uniprot id: L0DTU0
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

1255043:TVNIR RS16470
gene id: 1255043:TVNIR_RS16470
uniprot id: L0E1D5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1255043:TVNIR RS18065
gene id: 1255043:TVNIR_RS18065
uniprot id: L0E2G6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1255043:TVNIR RS11940
gene id: 1255043:TVNIR_RS11940
uniprot id: L0DYU5
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS11815
gene id: 1255043:TVNIR_RS11815
uniprot id: L0E0I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1255043:TVNIR RS16365
gene id: 1255043:TVNIR_RS16365
uniprot id: L0E1K7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1255043:TVNIR RS17095
gene id: 1255043:TVNIR_RS17095
uniprot id: L0E201
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1255043:TVNIR RS05640
gene id: 1255043:TVNIR_RS05640
uniprot id: L0DV87
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1255043:TVNIR RS11375
gene id: 1255043:TVNIR_RS11375
uniprot id: L0DWT0
names: Subcellular Location Annotation
messages: Cell inner membrane

1255043:TVNIR RS09265
gene id: 1255043:TVNIR_RS09265
uniprot id: L0DXE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1255043:TVNIR RS12155
gene id: 1255043:TVNIR_RS12155
uniprot id: L0DZ30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1255043:TVNIR RS16370
gene id: 1255043:TVNIR_RS16370
uniprot id: L0E377
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1255043:TVNIR RS14750
gene id: 1255043:TVNIR_RS14750
uniprot id: L0E0J1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1255043:TVNIR RS17760
gene id: 1255043:TVNIR_RS17760
uniprot id: L0E2B6
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1255043:TVNIR RS12115
gene id: 1255043:TVNIR_RS12115
uniprot id: L0DYY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1255043:TVNIR RS13245
gene id: 1255043:TVNIR_RS13245
uniprot id: L0DZM2
names: Similarity
messages: Belongs to the barstar family.

1255043:TVNIR RS13960
gene id: 1255043:TVNIR_RS13960
uniprot id: L0E1T6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1255043:TVNIR RS02705
gene id: 1255043:TVNIR_RS02705
uniprot id: L0DTG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1255043:TVNIR RS08505
gene id: 1255043:TVNIR_RS08505
uniprot id: L0DYP2
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1255043:TVNIR RS14885
gene id: 1255043:TVNIR_RS14885
uniprot id: L0DYX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1255043:TVNIR RS04545
gene id: 1255043:TVNIR_RS04545
uniprot id: L0DWC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

1255043:TVNIR RS13250
gene id: 1255043:TVNIR_RS13250
uniprot id: L0DZH0
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

1255043:TVNIR RS18245
gene id: 1255043:TVNIR_RS18245
uniprot id: L0E0W3
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1255043:TVNIR RS08350
gene id: 1255043:TVNIR_RS08350
uniprot id: L0DWQ8
names: Function
names: Similarity
messages: Belongs to the UbiT family.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Likely functions as an accessory factor.

1255043:TVNIR RS08535
gene id: 1255043:TVNIR_RS08535
uniprot id: L0DWU8
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS10365
gene id: 1255043:TVNIR_RS10365
uniprot id: L0DXV8
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

1255043:TVNIR RS13315
gene id: 1255043:TVNIR_RS13315
uniprot id: L0E1F4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1255043:TVNIR RS05565
gene id: 1255043:TVNIR_RS05565
uniprot id: L0DV73
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1255043:TVNIR RS01035
gene id: 1255043:TVNIR_RS01035
uniprot id: L0DSI0
names: Similarity
messages: Belongs to the fructosamine kinase family.

1255043:TVNIR RS03895
gene id: 1255043:TVNIR_RS03895
uniprot id: L0DU38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1255043:TVNIR RS08480
gene id: 1255043:TVNIR_RS08480
uniprot id: L0DYN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1255043:TVNIR RS16550
gene id: 1255043:TVNIR_RS16550
uniprot id: L0DZV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1255043:TVNIR RS14315
gene id: 1255043:TVNIR_RS14315
uniprot id: L0E202
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS16530
gene id: 1255043:TVNIR_RS16530
uniprot id: L0E1P0
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

1255043:TVNIR RS11645
gene id: 1255043:TVNIR_RS11645
uniprot id: L0E0F3
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1255043:TVNIR RS12635
gene id: 1255043:TVNIR_RS12635
uniprot id: L0E0Y2
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1255043:TVNIR RS01625
gene id: 1255043:TVNIR_RS01625
uniprot id: L0DSR7
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS17035
gene id: 1255043:TVNIR_RS17035
uniprot id: L0E1V3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1255043:TVNIR RS16310
gene id: 1255043:TVNIR_RS16310
uniprot id: L0E198
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1255043:TVNIR RS16850
gene id: 1255043:TVNIR_RS16850
uniprot id: L0E1K9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1255043:TVNIR RS07505
gene id: 1255043:TVNIR_RS07505
uniprot id: L0DY00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1255043:TVNIR RS00515
gene id: 1255043:TVNIR_RS00515
uniprot id: L0DS38
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS12495
gene id: 1255043:TVNIR_RS12495
uniprot id: L0DZ10
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1255043:TVNIR RS04050
gene id: 1255043:TVNIR_RS04050
uniprot id: L0DU84
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1255043:TVNIR RS12680
gene id: 1255043:TVNIR_RS12680
uniprot id: L0DXK6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1255043:TVNIR RS16835
gene id: 1255043:TVNIR_RS16835
uniprot id: L0E1U6
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1255043:TVNIR RS00265
gene id: 1255043:TVNIR_RS00265
uniprot id: L0DRZ9
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS07140
gene id: 1255043:TVNIR_RS07140
uniprot id: L0DVX7
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1255043:TVNIR RS00645
gene id: 1255043:TVNIR_RS00645
uniprot id: L0DU14
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

1255043:TVNIR RS20195
gene id: 1255043:TVNIR_RS20195
uniprot id: L0DY57
names: Similarity
names: Subunit
messages: Belongs to the Ahb/Nir family.
messages: Probably forms a complex composed of NirD, NirL, NirG and NirH. All proteins are required for the total conversion of siroheme to didecarboxysiroheme.

1255043:TVNIR RS05455
gene id: 1255043:TVNIR_RS05455
uniprot id: L0DWV4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

1255043:TVNIR RS10520
gene id: 1255043:TVNIR_RS10520
uniprot id: L0DY73
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

1255043:TVNIR RS12345
gene id: 1255043:TVNIR_RS12345
uniprot id: L0DYX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1255043:TVNIR RS14285
gene id: 1255043:TVNIR_RS14285
uniprot id: L0E039
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1255043:TVNIR RS05925
gene id: 1255043:TVNIR_RS05925
uniprot id: L0DTM5
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS00980
gene id: 1255043:TVNIR_RS00980
uniprot id: L0DSE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

1255043:TVNIR RS05770
gene id: 1255043:TVNIR_RS05770
uniprot id: L0DX45
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1255043:TVNIR RS17235
gene id: 1255043:TVNIR_RS17235
uniprot id: L0E3M3
names: Subcellular Location Annotation
messages: nucleolus

1255043:TVNIR RS01770
gene id: 1255043:TVNIR_RS01770
uniprot id: L0DSW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

1255043:TVNIR RS11615
gene id: 1255043:TVNIR_RS11615
uniprot id: L0DYR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1255043:TVNIR RS07820
gene id: 1255043:TVNIR_RS07820
uniprot id: L0DWG9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

1255043:TVNIR RS16525
gene id: 1255043:TVNIR_RS16525
uniprot id: L0DZU5
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

1255043:TVNIR RS18070
gene id: 1255043:TVNIR_RS18070
uniprot id: L0E2C5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1255043:TVNIR RS14495
gene id: 1255043:TVNIR_RS14495
uniprot id: L0E0D5
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

1255043:TVNIR RS12260
gene id: 1255043:TVNIR_RS12260
uniprot id: L0E0Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1255043:TVNIR RS17710
gene id: 1255043:TVNIR_RS17710
uniprot id: L0E2A8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1255043:TVNIR RS01250
gene id: 1255043:TVNIR_RS01250
uniprot id: L0DXJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1255043:TVNIR RS03755
gene id: 1255043:TVNIR_RS03755
uniprot id: L0DSB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1255043:TVNIR RS01430
gene id: 1255043:TVNIR_RS01430
uniprot id: L0DSP4
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1255043:TVNIR RS01220
gene id: 1255043:TVNIR_RS01220
uniprot id: L0DSL2
names: Activity Regulation
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c-552 family.
messages: Binds 1 Ca(2+) ion per monomer.
messages: Binds 8 heme groups covalently per monomer.
messages: Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process (PubMed:16500161, PubMed:22281743). Has very low activity toward hydroxylamine (PubMed:16500161). Has even lower activity toward sulfite (PubMed:16500161, PubMed:22281743). Sulfite reductase activity is maximal at neutral pH (PubMed:20944237).
messages: Homohexamer. Dimer of trimers.
messages: Inhibited by azide and cyanide. Subject to competitive inhibition by sulfite.
messages: Periplasm
messages: The thioether cross-link between Tyr-331 and Cys-333 may play a structural role in the active site cavity (PubMed:19393666). Besides, it may lower the pKa of the Tyr hydroxyl group (PubMed:19393666). An additional covalent bond between Tyr-331 and Gln-388 has been observed in some protein crystals, but this may be an artifact that is due to the formation of tyrosyl radicals when the protein is exposed to oxygen (PubMed:22281743).

1255043:TVNIR RS13920
gene id: 1255043:TVNIR_RS13920
uniprot id: L0DZV9
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1255043:TVNIR RS01585
gene id: 1255043:TVNIR_RS01585
uniprot id: L0DUM4
names: Similarity
messages: Belongs to the pyruvate kinase family.

1255043:TVNIR RS03595
gene id: 1255043:TVNIR_RS03595
uniprot id: L0DTY3
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1255043:TVNIR RS12005
gene id: 1255043:TVNIR_RS12005
uniprot id: L0DYZ7
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1255043:TVNIR RS08660
gene id: 1255043:TVNIR_RS08660
uniprot id: L0DWT3
names: Similarity
messages: Belongs to the SufE family.

1255043:TVNIR RS13585
gene id: 1255043:TVNIR_RS13585
uniprot id: L0DZX7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1255043:TVNIR RS09530
gene id: 1255043:TVNIR_RS09530
uniprot id: L0DVQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1255043:TVNIR RS06715
gene id: 1255043:TVNIR_RS06715
uniprot id: L0DXK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PsiE family.
messages: Cell inner membrane
messages: Membrane

1255043:TVNIR RS12195
gene id: 1255043:TVNIR_RS12195
uniprot id: L0DYV2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1255043:TVNIR RS00760
gene id: 1255043:TVNIR_RS00760
uniprot id: L0DQT2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1255043:TVNIR RS14845
gene id: 1255043:TVNIR_RS14845
uniprot id: L0E0N8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

1255043:TVNIR RS17585
gene id: 1255043:TVNIR_RS17585
uniprot id: L0E3T3
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

1255043:TVNIR RS02435
gene id: 1255043:TVNIR_RS02435
uniprot id: L0DV37
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1255043:TVNIR RS14230
gene id: 1255043:TVNIR_RS14230
uniprot id: L0E1Y4
names: Similarity
messages: Belongs to the SCO1/2 family.

1255043:TVNIR RS12620
gene id: 1255043:TVNIR_RS12620
uniprot id: L0DZ33
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1255043:TVNIR RS16885
gene id: 1255043:TVNIR_RS16885
uniprot id: L0E3G7
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1255043:TVNIR RS09690
gene id: 1255043:TVNIR_RS09690
uniprot id: L0DZA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell inner membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1255043:TVNIR RS16825
gene id: 1255043:TVNIR_RS16825
uniprot id: L0E1K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1255043:TVNIR RS14830
gene id: 1255043:TVNIR_RS14830
uniprot id: L0E0K5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1255043:TVNIR RS17325
gene id: 1255043:TVNIR_RS17325
uniprot id: L0E246
names: Similarity
messages: Belongs to the universal stress protein A family.

1255043:TVNIR RS11205
gene id: 1255043:TVNIR_RS11205
uniprot id: L0DYD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1255043:TVNIR RS02115
gene id: 1255043:TVNIR_RS02115
uniprot id: L0DT40
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1255043:TVNIR RS15410
gene id: 1255043:TVNIR_RS15410
uniprot id: L0E0Y9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1255043:TVNIR RS14875
gene id: 1255043:TVNIR_RS14875
uniprot id: L0E0L3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1255043:TVNIR RS08870
gene id: 1255043:TVNIR_RS08870
uniprot id: L0DVB7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1255043:TVNIR RS14775
gene id: 1255043:TVNIR_RS14775
uniprot id: L0E285
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1255043:TVNIR RS03865
gene id: 1255043:TVNIR_RS03865
uniprot id: L0DW02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1255043:TVNIR RS10300
gene id: 1255043:TVNIR_RS10300
uniprot id: L0DY01
names: Similarity
messages: Belongs to the BolA/IbaG family.

1255043:TVNIR RS12025
gene id: 1255043:TVNIR_RS12025
uniprot id: L0DX63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1255043:TVNIR RS01120
gene id: 1255043:TVNIR_RS01120
uniprot id: L0DSI2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1255043:TVNIR RS08460
gene id: 1255043:TVNIR_RS08460
uniprot id: L0DWT2
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1255043:TVNIR RS02960
gene id: 1255043:TVNIR_RS02960
uniprot id: L0DTL3
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

1255043:TVNIR RS12630
gene id: 1255043:TVNIR_RS12630
uniprot id: L0DZB6
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

1255043:TVNIR RS14115
gene id: 1255043:TVNIR_RS14115
uniprot id: L0E002
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO small chain family.
messages: Heterohexadecamer of 8 large and 8 small subunits.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site. Although the small subunit is not catalytic it is essential for maximal activity.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.

1255043:TVNIR RS10575
gene id: 1255043:TVNIR_RS10575
uniprot id: L0DZX0
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1255043:TVNIR RS01870
gene id: 1255043:TVNIR_RS01870
uniprot id: L0DSX0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1255043:TVNIR RS07900
gene id: 1255043:TVNIR_RS07900
uniprot id: L0DWE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1255043:TVNIR RS12230
gene id: 1255043:TVNIR_RS12230
uniprot id: L0DZ39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

1255043:TVNIR RS04190
gene id: 1255043:TVNIR_RS04190
uniprot id: L0DU83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

1255043:TVNIR RS12365
gene id: 1255043:TVNIR_RS12365
uniprot id: L0DZ27
names: Similarity
messages: Belongs to the UPF0102 family.

1255043:TVNIR RS07710
gene id: 1255043:TVNIR_RS07710
uniprot id: L0DW98
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS02000
gene id: 1255043:TVNIR_RS02000
uniprot id: L0DUU8
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1255043:TVNIR RS11460
gene id: 1255043:TVNIR_RS11460
uniprot id: L0E0C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1255043:TVNIR RS01840
gene id: 1255043:TVNIR_RS01840
uniprot id: L0DSY0
names: Similarity
messages: Belongs to the UPF0758 family.

1255043:TVNIR RS01885
gene id: 1255043:TVNIR_RS01885
uniprot id: L0DUS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

1255043:TVNIR RS00970
gene id: 1255043:TVNIR_RS00970
uniprot id: L0DUA7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

1255043:TVNIR RS17550
gene id: 1255043:TVNIR_RS17550
uniprot id: L0E0H1
names: Similarity
messages: Belongs to the RutC family.

1255043:TVNIR RS14440
gene id: 1255043:TVNIR_RS14440
uniprot id: L0E0F6
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS01780
gene id: 1255043:TVNIR_RS01780
uniprot id: L0DSX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1255043:TVNIR RS15430
gene id: 1255043:TVNIR_RS15430
uniprot id: L0E128
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1255043:TVNIR RS08820
gene id: 1255043:TVNIR_RS08820
uniprot id: L0DVA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1255043:TVNIR RS13305
gene id: 1255043:TVNIR_RS13305
uniprot id: L0DXY6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1255043:TVNIR RS00775
gene id: 1255043:TVNIR_RS00775
uniprot id: L0DSB7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1255043:TVNIR RS13310
gene id: 1255043:TVNIR_RS13310
uniprot id: L0DZS1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1255043:TVNIR RS03870
gene id: 1255043:TVNIR_RS03870
uniprot id: L0DU32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1255043:TVNIR RS11865
gene id: 1255043:TVNIR_RS11865
uniprot id: L0DYT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1255043:TVNIR RS02315
gene id: 1255043:TVNIR_RS02315
uniprot id: L0DT86
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1255043:TVNIR RS12660
gene id: 1255043:TVNIR_RS12660
uniprot id: L0DZC2
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1255043:TVNIR RS10455
gene id: 1255043:TVNIR_RS10455
uniprot id: L0DZU7
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS12715
gene id: 1255043:TVNIR_RS12715
uniprot id: L0DZ96
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1255043:TVNIR RS05645
gene id: 1255043:TVNIR_RS05645
uniprot id: L0DX20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1255043:TVNIR RS14590
gene id: 1255043:TVNIR_RS14590
uniprot id: L0E0I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1255043:TVNIR RS04045
gene id: 1255043:TVNIR_RS04045
uniprot id: L0DSG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

1255043:TVNIR RS06025
gene id: 1255043:TVNIR_RS06025
uniprot id: L0DX94
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS12390
gene id: 1255043:TVNIR_RS12390
uniprot id: L0DZ32
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1255043:TVNIR RS14380
gene id: 1255043:TVNIR_RS14380
uniprot id: L0E059
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS11985
gene id: 1255043:TVNIR_RS11985
uniprot id: L0E0L4
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1255043:TVNIR RS16270
gene id: 1255043:TVNIR_RS16270
uniprot id: L0E1J3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1255043:TVNIR RS15395
gene id: 1255043:TVNIR_RS15395
uniprot id: L0DZ97
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1255043:TVNIR RS12065
gene id: 1255043:TVNIR_RS12065
uniprot id: L0DYX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1255043:TVNIR RS13295
gene id: 1255043:TVNIR_RS13295
uniprot id: L0DZN0
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1255043:TVNIR RS05505
gene id: 1255043:TVNIR_RS05505
uniprot id: L0DWW7
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

1255043:TVNIR RS08220
gene id: 1255043:TVNIR_RS08220
uniprot id: L0DWT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

1255043:TVNIR RS17990
gene id: 1255043:TVNIR_RS17990
uniprot id: L0E437
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

1255043:TVNIR RS12190
gene id: 1255043:TVNIR_RS12190
uniprot id: L0DYZ6
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1255043:TVNIR RS04810
gene id: 1255043:TVNIR_RS04810
uniprot id: L0DUQ0
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

1255043:TVNIR RS04990
gene id: 1255043:TVNIR_RS04990
uniprot id: L0DT21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1255043:TVNIR RS16050
gene id: 1255043:TVNIR_RS16050
uniprot id: L0E1E8
names: Similarity
messages: Belongs to the WrbA family.

1255043:TVNIR RS02995
gene id: 1255043:TVNIR_RS02995
uniprot id: L0DRX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TraY family.
messages: Cytoplasm

1255043:TVNIR RS15145
gene id: 1255043:TVNIR_RS15145
uniprot id: L0E0M0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1255043:TVNIR RS13110
gene id: 1255043:TVNIR_RS13110
uniprot id: L0DZP0
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1255043:TVNIR RS05145
gene id: 1255043:TVNIR_RS05145
uniprot id: L0DUU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

1255043:TVNIR RS08490
gene id: 1255043:TVNIR_RS08490
uniprot id: L0DWP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1255043:TVNIR RS08595
gene id: 1255043:TVNIR_RS08595
uniprot id: L0DV58
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1255043:TVNIR RS02625
gene id: 1255043:TVNIR_RS02625
uniprot id: L0DV76
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS00640
gene id: 1255043:TVNIR_RS00640
uniprot id: L0DS83
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

1255043:TVNIR RS04065
gene id: 1255043:TVNIR_RS04065
uniprot id: L0DU56
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

1255043:TVNIR RS17790
gene id: 1255043:TVNIR_RS17790
uniprot id: L0E0N9
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1255043:TVNIR RS13035
gene id: 1255043:TVNIR_RS13035
uniprot id: L0DZM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1255043:TVNIR RS17695
gene id: 1255043:TVNIR_RS17695
uniprot id: L0E251
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

1255043:TVNIR RS10420
gene id: 1255043:TVNIR_RS10420
uniprot id: L0DXX1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1255043:TVNIR RS15385
gene id: 1255043:TVNIR_RS15385
uniprot id: L0E0Y4
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1255043:TVNIR RS03080
gene id: 1255043:TVNIR_RS03080
uniprot id: L0DTP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TraY family.
messages: Cytoplasm

1255043:TVNIR RS00790
gene id: 1255043:TVNIR_RS00790
uniprot id: L0DSC9
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

1255043:TVNIR RS02875
gene id: 1255043:TVNIR_RS02875
uniprot id: L0DRV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TraY family.
messages: Cytoplasm

1255043:TVNIR RS01225
gene id: 1255043:TVNIR_RS01225
uniprot id: L0DSK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

1255043:TVNIR RS04825
gene id: 1255043:TVNIR_RS04825
uniprot id: L0DUM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1255043:TVNIR RS11470
gene id: 1255043:TVNIR_RS11470
uniprot id: L0DYE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1255043:TVNIR RS03940
gene id: 1255043:TVNIR_RS03940
uniprot id: L0DU48
names: Similarity
messages: Belongs to the HesB/IscA family.

1255043:TVNIR RS03840
gene id: 1255043:TVNIR_RS03840
uniprot id: L0DVZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1255043:TVNIR RS14345
gene id: 1255043:TVNIR_RS14345
uniprot id: L0E204
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1255043:TVNIR RS00315
gene id: 1255043:TVNIR_RS00315
uniprot id: L0DS16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1255043:TVNIR RS01940
gene id: 1255043:TVNIR_RS01940
uniprot id: L0DSY8
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1255043:TVNIR RS09235
gene id: 1255043:TVNIR_RS09235
uniprot id: L0DVJ5
names: Similarity
messages: Belongs to the skp family.

1255043:TVNIR RS04805
gene id: 1255043:TVNIR_RS04805
uniprot id: L0DSX9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1255043:TVNIR RS03195
gene id: 1255043:TVNIR_RS03195
uniprot id: L0DTQ9
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1255043:TVNIR RS11860
gene id: 1255043:TVNIR_RS11860
uniprot id: L0E0J4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1255043:TVNIR RS03250
gene id: 1255043:TVNIR_RS03250
uniprot id: L0DS42
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1255043:TVNIR RS11665
gene id: 1255043:TVNIR_RS11665
uniprot id: L0E0F8
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS01010
gene id: 1255043:TVNIR_RS01010
uniprot id: L0DQU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1255043:TVNIR RS16385
gene id: 1255043:TVNIR_RS16385
uniprot id: L0E1L2
names: Similarity
messages: Belongs to the BolA/IbaG family.

1255043:TVNIR RS00460
gene id: 1255043:TVNIR_RS00460
uniprot id: L0DTW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1255043:TVNIR RS05800
gene id: 1255043:TVNIR_RS05800
uniprot id: L0DTK6
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1255043:TVNIR RS05600
gene id: 1255043:TVNIR_RS05600
uniprot id: L0DV54
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1255043:TVNIR RS06110
gene id: 1255043:TVNIR_RS06110
uniprot id: L0DTQ4
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1255043:TVNIR RS11900
gene id: 1255043:TVNIR_RS11900
uniprot id: L0DYP1
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1255043:TVNIR RS05170
gene id: 1255043:TVNIR_RS05170
uniprot id: L0DUV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

1255043:TVNIR RS01985
gene id: 1255043:TVNIR_RS01985
uniprot id: L0DSZ8
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1255043:TVNIR RS08635
gene id: 1255043:TVNIR_RS08635
uniprot id: L0DWS8
names: Similarity
messages: Belongs to the HesB/IscA family.

1255043:TVNIR RS07220
gene id: 1255043:TVNIR_RS07220
uniprot id: L0DVZ3
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

1255043:TVNIR RS11655
gene id: 1255043:TVNIR_RS11655
uniprot id: L0DYI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1255043:TVNIR RS08625
gene id: 1255043:TVNIR_RS08625
uniprot id: L0DYR6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1255043:TVNIR RS16800
gene id: 1255043:TVNIR_RS16800
uniprot id: L0E1J9
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS01935
gene id: 1255043:TVNIR_RS01935
uniprot id: L0DSZ9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1255043:TVNIR RS06450
gene id: 1255043:TVNIR_RS06450
uniprot id: L0DVP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1255043:TVNIR RS15940
gene id: 1255043:TVNIR_RS15940
uniprot id: L0E183
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1255043:TVNIR RS05910
gene id: 1255043:TVNIR_RS05910
uniprot id: L0DVE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1255043:TVNIR RS12920
gene id: 1255043:TVNIR_RS12920
uniprot id: L0DZK1
names: Similarity
messages: Belongs to the UPF0047 family.

1255043:TVNIR RS02180
gene id: 1255043:TVNIR_RS02180
uniprot id: L0DUY4
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1255043:TVNIR RS02085
gene id: 1255043:TVNIR_RS02085
uniprot id: L0DT41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

1255043:TVNIR RS16520
gene id: 1255043:TVNIR_RS16520
uniprot id: L0E1E6
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1255043:TVNIR RS10565
gene id: 1255043:TVNIR_RS10565
uniprot id: L0DWE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AceK family.
messages: Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
messages: Cytoplasm

1255043:TVNIR RS13140
gene id: 1255043:TVNIR_RS13140
uniprot id: L0DZP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1255043:TVNIR RS14280
gene id: 1255043:TVNIR_RS14280
uniprot id: L0E1Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

1255043:TVNIR RS08655
gene id: 1255043:TVNIR_RS08655
uniprot id: L0DWX2
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1255043:TVNIR RS09525
gene id: 1255043:TVNIR_RS09525
uniprot id: L0DXA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1255043:TVNIR RS10560
gene id: 1255043:TVNIR_RS10560
uniprot id: L0DXZ9
names: Cofactor
messages: Can also use Mn(2+) ion.

1255043:TVNIR RS12845
gene id: 1255043:TVNIR_RS12845
uniprot id: L0DXP5
names: Caution
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

1255043:TVNIR RS03065
gene id: 1255043:TVNIR_RS03065
uniprot id: L0DTN2
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

1255043:TVNIR RS00070
gene id: 1255043:TVNIR_RS00070
uniprot id: L0DRV8
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1255043:TVNIR RS15415
gene id: 1255043:TVNIR_RS15415
uniprot id: L0E0U5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

1255043:TVNIR RS03115
gene id: 1255043:TVNIR_RS03115
uniprot id: L0DTN6
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1255043:TVNIR RS10990
gene id: 1255043:TVNIR_RS10990
uniprot id: L0E031
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1255043:TVNIR RS17230
gene id: 1255043:TVNIR_RS17230
uniprot id: L0E228
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

1255043:TVNIR RS14755
gene id: 1255043:TVNIR_RS14755
uniprot id: L0E0E6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1255043:TVNIR RS09685
gene id: 1255043:TVNIR_RS09685
uniprot id: L0DVU1
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS05150
gene id: 1255043:TVNIR_RS05150
uniprot id: L0DT53
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1255043:TVNIR RS15150
gene id: 1255043:TVNIR_RS15150
uniprot id: L0DZ29
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1255043:TVNIR RS09575
gene id: 1255043:TVNIR_RS09575
uniprot id: L0DVR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SelU family.
messages: Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
messages: Monomer.

1255043:TVNIR RS03990
gene id: 1255043:TVNIR_RS03990
uniprot id: L0DU60
names: Similarity
messages: Belongs to the DsrF/TusC family.

1255043:TVNIR RS02945
gene id: 1255043:TVNIR_RS02945
uniprot id: L0DRX0
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

1255043:TVNIR RS06640
gene id: 1255043:TVNIR_RS06640
uniprot id: L0DU15
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

1255043:TVNIR RS07420
gene id: 1255043:TVNIR_RS07420
uniprot id: L0DUG9
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1255043:TVNIR RS13120
gene id: 1255043:TVNIR_RS13120
uniprot id: L0DZJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1255043:TVNIR RS18030
gene id: 1255043:TVNIR_RS18030
uniprot id: L0E0T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

1255043:TVNIR RS17320
gene id: 1255043:TVNIR_RS17320
uniprot id: L0E1W4
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS12625
gene id: 1255043:TVNIR_RS12625
uniprot id: L0DXJ3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

1255043:TVNIR RS13070
gene id: 1255043:TVNIR_RS13070
uniprot id: L0DZE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

1255043:TVNIR RS14565
gene id: 1255043:TVNIR_RS14565
uniprot id: L0DYQ2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1255043:TVNIR RS04180
gene id: 1255043:TVNIR_RS04180
uniprot id: L0DW57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

1255043:TVNIR RS04200
gene id: 1255043:TVNIR_RS04200
uniprot id: L0DUB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1255043:TVNIR RS07325
gene id: 1255043:TVNIR_RS07325
uniprot id: L0DW71
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

1255043:TVNIR RS13325
gene id: 1255043:TVNIR_RS13325
uniprot id: L0DZI3
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1255043:TVNIR RS09630
gene id: 1255043:TVNIR_RS09630
uniprot id: L0DXD6
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

1255043:TVNIR RS12535
gene id: 1255043:TVNIR_RS12535
uniprot id: L0DZ95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1255043:TVNIR RS11310
gene id: 1255043:TVNIR_RS11310
uniprot id: L0DYB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1255043:TVNIR RS03580
gene id: 1255043:TVNIR_RS03580
uniprot id: L0DS91
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1255043:TVNIR RS00875
gene id: 1255043:TVNIR_RS00875
uniprot id: L0DSF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

1255043:TVNIR RS18050
gene id: 1255043:TVNIR_RS18050
uniprot id: L0E2C1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1255043:TVNIR RS17245
gene id: 1255043:TVNIR_RS17245
uniprot id: L0E1U8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

1255043:TVNIR RS12410
gene id: 1255043:TVNIR_RS12410
uniprot id: L0E0T5
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1255043:TVNIR RS18200
gene id: 1255043:TVNIR_RS18200
uniprot id: L0E0V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

1255043:TVNIR RS02920
gene id: 1255043:TVNIR_RS02920
uniprot id: L0DRW5
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1255043:TVNIR RS16155
gene id: 1255043:TVNIR_RS16155
uniprot id: L0E1C7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1255043:TVNIR RS20965
gene id: 1255043:TVNIR_RS20965
uniprot id: L0DYJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

1255043:TVNIR RS16345
gene id: 1255043:TVNIR_RS16345
uniprot id: L0E1K3
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

1255043:TVNIR RS09040
gene id: 1255043:TVNIR_RS09040
uniprot id: L0DX05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

1255043:TVNIR RS17205
gene id: 1255043:TVNIR_RS17205
uniprot id: L0E094
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1255043:TVNIR RS12350
gene id: 1255043:TVNIR_RS12350
uniprot id: L0DXD2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1255043:TVNIR RS05105
gene id: 1255043:TVNIR_RS05105
uniprot id: L0DUV9
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Member of a two-component regulatory system.

1255043:TVNIR RS08845
gene id: 1255043:TVNIR_RS08845
uniprot id: L0DVB2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

1255043:TVNIR RS04985
gene id: 1255043:TVNIR_RS04985
uniprot id: L0DUR0
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1255043:TVNIR RS08225
gene id: 1255043:TVNIR_RS08225
uniprot id: L0DYJ0
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS06840
gene id: 1255043:TVNIR_RS06840
uniprot id: L0DXN1
names: Similarity
messages: Belongs to the aspartokinase family.

1255043:TVNIR RS01895
gene id: 1255043:TVNIR_RS01895
uniprot id: L0DSX5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1255043:TVNIR RS05590
gene id: 1255043:TVNIR_RS05590
uniprot id: L0DV78
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1255043:TVNIR RS01560
gene id: 1255043:TVNIR_RS01560
uniprot id: L0DUL9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1255043:TVNIR RS12095
gene id: 1255043:TVNIR_RS12095
uniprot id: L0DYT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1255043:TVNIR RS12770
gene id: 1255043:TVNIR_RS12770
uniprot id: L0DZ60
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

1255043:TVNIR RS09210
gene id: 1255043:TVNIR_RS09210
uniprot id: L0DVJ0
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1255043:TVNIR RS10320
gene id: 1255043:TVNIR_RS10320
uniprot id: L0DW87
names: Similarity
messages: Belongs to the UPF0250 family.

1255043:TVNIR RS16320
gene id: 1255043:TVNIR_RS16320
uniprot id: L0E1J7
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

1255043:TVNIR RS09435
gene id: 1255043:TVNIR_RS09435
uniprot id: L0DVN1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

1255043:TVNIR RS13940
gene id: 1255043:TVNIR_RS13940
uniprot id: L0E017
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

1255043:TVNIR RS08915
gene id: 1255043:TVNIR_RS08915
uniprot id: L0DWY3
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1255043:TVNIR RS00290
gene id: 1255043:TVNIR_RS00290
uniprot id: L0DS11
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

1255043:TVNIR RS18085
gene id: 1255043:TVNIR_RS18085
uniprot id: L0E2L2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1255043:TVNIR RS14705
gene id: 1255043:TVNIR_RS14705
uniprot id: L0E0D4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1255043:TVNIR RS06875
gene id: 1255043:TVNIR_RS06875
uniprot id: L0DVS2
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated Csm5 family.
messages: This subunit might be involved in maturation of a crRNA intermediate to its mature form.

1255043:TVNIR RS12100
gene id: 1255043:TVNIR_RS12100
uniprot id: L0DX81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1255043:TVNIR RS04540
gene id: 1255043:TVNIR_RS04540
uniprot id: L0DUJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhE family.
messages: Cytoplasm
messages: Necessary for formate dehydrogenase activity.

1255043:TVNIR RS08795
gene id: 1255043:TVNIR_RS08795
uniprot id: L0DWW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

1255043:TVNIR RS01130
gene id: 1255043:TVNIR_RS01130
uniprot id: L0DQV7
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1255043:TVNIR RS14305
gene id: 1255043:TVNIR_RS14305
uniprot id: L0DYJ2
names: Similarity
messages: Belongs to the UPF0229 family.

1255043:TVNIR RS01615
gene id: 1255043:TVNIR_RS01615
uniprot id: L0DUM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1255043:TVNIR RS12000
gene id: 1255043:TVNIR_RS12000
uniprot id: L0DX58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1255043:TVNIR RS12085
gene id: 1255043:TVNIR_RS12085
uniprot id: L0E0N0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1255043:TVNIR RS00415
gene id: 1255043:TVNIR_RS00415
uniprot id: L0DS37
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell inner membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1255043:TVNIR RS09240
gene id: 1255043:TVNIR_RS09240
uniprot id: L0DXD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1255043:TVNIR RS12305
gene id: 1255043:TVNIR_RS12305
uniprot id: L0DZ52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

1255043:TVNIR RS00785
gene id: 1255043:TVNIR_RS00785
uniprot id: L0DQT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

1255043:TVNIR RS13125
gene id: 1255043:TVNIR_RS13125
uniprot id: L0DZE7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1255043:TVNIR RS11690
gene id: 1255043:TVNIR_RS11690
uniprot id: L0E0G2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1255043:TVNIR RS09230
gene id: 1255043:TVNIR_RS09230
uniprot id: L0DX46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1255043:TVNIR RS06940
gene id: 1255043:TVNIR_RS06940
uniprot id: L0DVV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRISPR system Cmr5 family.
messages: Cytoplasm

1255043:TVNIR RS04955
gene id: 1255043:TVNIR_RS04955
uniprot id: L0DUR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1255043:TVNIR RS01100
gene id: 1255043:TVNIR_RS01100
uniprot id: L0DSG7
names: Similarity
messages: Belongs to the GARS family.

1255043:TVNIR RS14205
gene id: 1255043:TVNIR_RS14205
uniprot id: L0E1Y0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Monomer.

1255043:TVNIR RS06855
gene id: 1255043:TVNIR_RS06855
uniprot id: L0DU54
names: Similarity
messages: Belongs to the CRISPR-associated Cas10/Csm1 family.

1255043:TVNIR RS09045
gene id: 1255043:TVNIR_RS09045
uniprot id: L0DVF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1255043:TVNIR RS12120
gene id: 1255043:TVNIR_RS12120
uniprot id: L0DYT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1255043:TVNIR RS12640
gene id: 1255043:TVNIR_RS12640
uniprot id: L0DZ82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1255043:TVNIR RS08715
gene id: 1255043:TVNIR_RS08715
uniprot id: L0DV81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1255043:TVNIR RS13860
gene id: 1255043:TVNIR_RS13860
uniprot id: L0DY95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

1255043:TVNIR RS16135
gene id: 1255043:TVNIR_RS16135
uniprot id: L0E167
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1255043:TVNIR RS06210
gene id: 1255043:TVNIR_RS06210
uniprot id: L0DVJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NapB family.
messages: Periplasm

1255043:TVNIR RS12255
gene id: 1255043:TVNIR_RS12255
uniprot id: L0DZ44
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1255043:TVNIR RS11530
gene id: 1255043:TVNIR_RS11530
uniprot id: L0DWW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1255043:TVNIR RS05960
gene id: 1255043:TVNIR_RS05960
uniprot id: L0DVB9
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1255043:TVNIR RS01385
gene id: 1255043:TVNIR_RS01385
uniprot id: L0DSM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1255043:TVNIR RS17635
gene id: 1255043:TVNIR_RS17635
uniprot id: L0E3U3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

1255043:TVNIR RS16185
gene id: 1255043:TVNIR_RS16185
uniprot id: L0E177
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1255043:TVNIR RS14725
gene id: 1255043:TVNIR_RS14725
uniprot id: L0E0I6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1255043:TVNIR RS12540
gene id: 1255043:TVNIR_RS12540
uniprot id: L0E0W1
names: Similarity
messages: Belongs to the thioredoxin family.

1255043:TVNIR RS15910
gene id: 1255043:TVNIR_RS15910
uniprot id: L0E2Z3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1255043:TVNIR RS08975
gene id: 1255043:TVNIR_RS08975
uniprot id: L0DX78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1255043:TVNIR RS10375
gene id: 1255043:TVNIR_RS10375
uniprot id: L0DY46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1255043:TVNIR RS09145
gene id: 1255043:TVNIR_RS09145
uniprot id: L0DXB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1255043:TVNIR RS17060
gene id: 1255043:TVNIR_RS17060
uniprot id: L0E1Q9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1255043:TVNIR RS01390
gene id: 1255043:TVNIR_RS01390
uniprot id: L0DR01
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1255043:TVNIR RS12165
gene id: 1255043:TVNIR_RS12165
uniprot id: L0DYZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1255043:TVNIR RS09360
gene id: 1255043:TVNIR_RS09360
uniprot id: L0DX74
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS01315
gene id: 1255043:TVNIR_RS01315
uniprot id: L0DSM9
names: Similarity
messages: Belongs to the glycosyltransferase 1 family.

1255043:TVNIR RS06425
gene id: 1255043:TVNIR_RS06425
uniprot id: L0DVN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1255043:TVNIR RS03795
gene id: 1255043:TVNIR_RS03795
uniprot id: L0DU21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1255043:TVNIR RS07495
gene id: 1255043:TVNIR_RS07495
uniprot id: L0DUI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1255043:TVNIR RS05675
gene id: 1255043:TVNIR_RS05675
uniprot id: L0DV48
names: Similarity
messages: Belongs to the TrpF family.

1255043:TVNIR RS11660
gene id: 1255043:TVNIR_RS11660
uniprot id: L0DWY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1255043:TVNIR RS04500
gene id: 1255043:TVNIR_RS04500
uniprot id: L0DWB5
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1255043:TVNIR RS08420
gene id: 1255043:TVNIR_RS08420
uniprot id: L0DV29
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1255043:TVNIR RS09495
gene id: 1255043:TVNIR_RS09495
uniprot id: L0DZ69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1255043:TVNIR RS12355
gene id: 1255043:TVNIR_RS12355
uniprot id: L0DZ61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1255043:TVNIR RS12450
gene id: 1255043:TVNIR_RS12450
uniprot id: L0DXF5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

1255043:TVNIR RS14610
gene id: 1255043:TVNIR_RS14610
uniprot id: L0DYR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1255043:TVNIR RS07200
gene id: 1255043:TVNIR_RS07200
uniprot id: L0DUC3
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS17225
gene id: 1255043:TVNIR_RS17225
uniprot id: L0E0A1
names: Subcellular Location Annotation
messages: Membrane

1255043:TVNIR RS15235
gene id: 1255043:TVNIR_RS15235
uniprot id: L0E0U2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1255043:TVNIR RS10410
gene id: 1255043:TVNIR_RS10410
uniprot id: L0DZT5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1255043:TVNIR RS02035
gene id: 1255043:TVNIR_RS02035
uniprot id: L0DT08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

1255043:TVNIR RS12205
gene id: 1255043:TVNIR_RS12205
uniprot id: L0DYY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1255043:TVNIR RS10635
gene id: 1255043:TVNIR_RS10635
uniprot id: L0DZX9
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

1255043:TVNIR RS08880
gene id: 1255043:TVNIR_RS08880
uniprot id: L0DYW3
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1255043:TVNIR RS17175
gene id: 1255043:TVNIR_RS17175
uniprot id: L0E1T3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Non-allosteric.

1255043:TVNIR RS06415
gene id: 1255043:TVNIR_RS06415
uniprot id: L0DVI7
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

1255043:TVNIR RS03805
gene id: 1255043:TVNIR_RS03805
uniprot id: L0DSC1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1255043:TVNIR RS14790
gene id: 1255043:TVNIR_RS14790
uniprot id: L0DYV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1255043:TVNIR RS07435
gene id: 1255043:TVNIR_RS07435
uniprot id: L0DW55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1255043:TVNIR RS08520
gene id: 1255043:TVNIR_RS08520
uniprot id: L0DV46
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1255043:TVNIR RS00755
gene id: 1255043:TVNIR_RS00755
uniprot id: L0DSA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1255043:TVNIR RS02345
gene id: 1255043:TVNIR_RS02345
uniprot id: L0DRJ8
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1255043:TVNIR RS09565
gene id: 1255043:TVNIR_RS09565
uniprot id: L0DXF8
names: Similarity
messages: Belongs to the universal stress protein A family.

1255043:TVNIR RS10315
gene id: 1255043:TVNIR_RS10315
uniprot id: L0DXT3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1255043:TVNIR RS14120
gene id: 1255043:TVNIR_RS14120
uniprot id: L0DYE9
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO large chain family. Type I subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterohexadecamer of 8 large chains and 8 small chains.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.

1255043:TVNIR RS12910
gene id: 1255043:TVNIR_RS12910
uniprot id: L0DZF6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1255043:TVNIR RS03855
gene id: 1255043:TVNIR_RS03855
uniprot id: L0DSC8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1255043:TVNIR RS03680
gene id: 1255043:TVNIR_RS03680
uniprot id: L0DTY9
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1255043:TVNIR RS04415
gene id: 1255043:TVNIR_RS04415
uniprot id: L0DSP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1255043:TVNIR RS17880
gene id: 1255043:TVNIR_RS17880
uniprot id: L0E0Q7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

1255043:TVNIR RS12710
gene id: 1255043:TVNIR_RS12710
uniprot id: L0DZD2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1255043:TVNIR RS00075
gene id: 1255043:TVNIR_RS00075
uniprot id: L0DTN1
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1255043:TVNIR RS07380
gene id: 1255043:TVNIR_RS07380
uniprot id: L0DW45
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1255043:TVNIR RS14250
gene id: 1255043:TVNIR_RS14250
uniprot id: L0E0B8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1255043:TVNIR RS13760
gene id: 1255043:TVNIR_RS13760
uniprot id: L0E1P5
names: Similarity
messages: Belongs to the histone deacetylase family.

1255043:TVNIR RS01415
gene id: 1255043:TVNIR_RS01415
uniprot id: L0DR06
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.