1249552:PS2015 RS12230
gene id: 1249552:PS2015_RS12230
uniprot id: A0A0S2KG26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1249552:PS2015 RS06560
gene id: 1249552:PS2015_RS06560
uniprot id: A0A0S2KCE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

1249552:PS2015 RS14945
gene id: 1249552:PS2015_RS14945
uniprot id: A0A0S2KHU7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1249552:PS2015 RS06270
gene id: 1249552:PS2015_RS06270
uniprot id: A0A0S2KD90
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1249552:PS2015 RS08920
gene id: 1249552:PS2015_RS08920
uniprot id: A0A0S2KE53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. WecA subfamily.
messages: Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55).
messages: Cell inner membrane
messages: Membrane

1249552:PS2015 RS03345
gene id: 1249552:PS2015_RS03345
uniprot id: A0A0S2KAJ3
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1249552:PS2015 RS08565
gene id: 1249552:PS2015_RS08565
uniprot id: A0A0S2KEG7
names: Similarity
messages: Belongs to the ParB family.

1249552:PS2015 RS10700
gene id: 1249552:PS2015_RS10700
uniprot id: A0A0S2KFF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1249552:PS2015 RS01630
gene id: 1249552:PS2015_RS01630
uniprot id: A0A0S2K9L7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
messages: Binds 2 manganese ions per subunit.
messages: Splits dipeptides with a prolyl residue in the C-terminal position.

1249552:PS2015 RS14015
gene id: 1249552:PS2015_RS14015
uniprot id: A0A0S2KGI4
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1249552:PS2015 RS08395
gene id: 1249552:PS2015_RS08395
uniprot id: A0A0S2KDE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1249552:PS2015 RS06085
gene id: 1249552:PS2015_RS06085
uniprot id: A0A0S2KCP3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1249552:PS2015 RS00105
gene id: 1249552:PS2015_RS00105
uniprot id: A0A0S2K9P7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1249552:PS2015 RS08365
gene id: 1249552:PS2015_RS08365
uniprot id: A0A0S2KDD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1249552:PS2015 RS02815
gene id: 1249552:PS2015_RS02815
uniprot id: A0A0S2KB09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1249552:PS2015 RS10280
gene id: 1249552:PS2015_RS10280
uniprot id: A0A0S2KF76
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

1249552:PS2015 RS07435
gene id: 1249552:PS2015_RS07435
uniprot id: A0A0S2KD99
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1249552:PS2015 RS10890
gene id: 1249552:PS2015_RS10890
uniprot id: A0A0S2KEZ6
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1249552:PS2015 RS06195
gene id: 1249552:PS2015_RS06195
uniprot id: A0A0S2KCT7
names: Similarity
messages: Belongs to the threonine synthase family.

1249552:PS2015 RS08505
gene id: 1249552:PS2015_RS08505
uniprot id: A0A0S2KE12
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1249552:PS2015 RS02170
gene id: 1249552:PS2015_RS02170
uniprot id: A0A0S2K9X9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1249552:PS2015 RS08325
gene id: 1249552:PS2015_RS08325
uniprot id: A0A0S2KEB0
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1249552:PS2015 RS06950
gene id: 1249552:PS2015_RS06950
uniprot id: A0A0S2KCK1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1249552:PS2015 RS04580
gene id: 1249552:PS2015_RS04580
uniprot id: A0A0S2KBC5
names: Function
names: Similarity
messages: Belongs to the acetyltransferase family. EctA subfamily.
messages: Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.

1249552:PS2015 RS14275
gene id: 1249552:PS2015_RS14275
uniprot id: A0A0S2KGK9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1249552:PS2015 RS11350
gene id: 1249552:PS2015_RS11350
uniprot id: A0A0S2KFK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1249552:PS2015 RS09240
gene id: 1249552:PS2015_RS09240
uniprot id: A0A0S2KEY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1249552:PS2015 RS10235
gene id: 1249552:PS2015_RS10235
uniprot id: A0A0S2KEC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1249552:PS2015 RS12670
gene id: 1249552:PS2015_RS12670
uniprot id: A0A0S2KG45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1249552:PS2015 RS06520
gene id: 1249552:PS2015_RS06520
uniprot id: A0A0S2KDC8
names: Similarity
messages: Belongs to the PrpF family.

1249552:PS2015 RS07160
gene id: 1249552:PS2015_RS07160
uniprot id: A0A0S2KCR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1249552:PS2015 RS07650
gene id: 1249552:PS2015_RS07650
uniprot id: A0A0S2KDW7
names: Similarity
messages: Belongs to the peptidase S41A family.

1249552:PS2015 RS09100
gene id: 1249552:PS2015_RS09100
uniprot id: A0A0S2KDT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1249552:PS2015 RS11195
gene id: 1249552:PS2015_RS11195
uniprot id: A0A0S2KFB3
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

1249552:PS2015 RS04985
gene id: 1249552:PS2015_RS04985
uniprot id: A0A0S2KBU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1249552:PS2015 RS05550
gene id: 1249552:PS2015_RS05550
uniprot id: A0A0S2KC74
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1249552:PS2015 RS00910
gene id: 1249552:PS2015_RS00910
uniprot id: A0A0S2K9W9
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

1249552:PS2015 RS07770
gene id: 1249552:PS2015_RS07770
uniprot id: A0A0S2KDF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1249552:PS2015 RS07940
gene id: 1249552:PS2015_RS07940
uniprot id: A0A0S2KDI9
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1249552:PS2015 RS12355
gene id: 1249552:PS2015_RS12355
uniprot id: A0A0S2KFI8
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1249552:PS2015 RS13390
gene id: 1249552:PS2015_RS13390
uniprot id: A0A0S2KGQ1
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1249552:PS2015 RS00330
gene id: 1249552:PS2015_RS00330
uniprot id: A0A0S2K8V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

1249552:PS2015 RS00435
gene id: 1249552:PS2015_RS00435
uniprot id: A0A0S2K8X4
names: Cofactor
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.

1249552:PS2015 RS10035
gene id: 1249552:PS2015_RS10035
uniprot id: A0A0S2KE93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1249552:PS2015 RS05705
gene id: 1249552:PS2015_RS05705
uniprot id: A0A0S2KCW9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1249552:PS2015 RS09365
gene id: 1249552:PS2015_RS09365
uniprot id: A0A0S2KE00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

1249552:PS2015 RS08900
gene id: 1249552:PS2015_RS08900
uniprot id: A0A0S2KDP7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1249552:PS2015 RS08245
gene id: 1249552:PS2015_RS08245
uniprot id: A0A0S2KDV4
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1249552:PS2015 RS06650
gene id: 1249552:PS2015_RS06650
uniprot id: A0A0S2KCF6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1249552:PS2015 RS11755
gene id: 1249552:PS2015_RS11755
uniprot id: A0A0S2KFT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1249552:PS2015 RS12225
gene id: 1249552:PS2015_RS12225
uniprot id: A0A0S2KGJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1249552:PS2015 RS09250
gene id: 1249552:PS2015_RS09250
uniprot id: A0A0S2KEN5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1249552:PS2015 RS13775
gene id: 1249552:PS2015_RS13775
uniprot id: A0A0S2KGX9
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1249552:PS2015 RS06695
gene id: 1249552:PS2015_RS06695
uniprot id: A0A0S2KD24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1249552:PS2015 RS09340
gene id: 1249552:PS2015_RS09340
uniprot id: A0A0S2KDX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1249552:PS2015 RS09910
gene id: 1249552:PS2015_RS09910
uniprot id: A0A0S2KE85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1249552:PS2015 RS14910
gene id: 1249552:PS2015_RS14910
uniprot id: A0A0S2KH10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

1249552:PS2015 RS01485
gene id: 1249552:PS2015_RS01485
uniprot id: A0A0S2KAK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

1249552:PS2015 RS08075
gene id: 1249552:PS2015_RS08075
uniprot id: A0A0S2KE57
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1249552:PS2015 RS04015
gene id: 1249552:PS2015_RS04015
uniprot id: A0A0S2KAX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1249552:PS2015 RS02045
gene id: 1249552:PS2015_RS02045
uniprot id: A0A0S2KAK1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1249552:PS2015 RS11895
gene id: 1249552:PS2015_RS11895
uniprot id: A0A0S2KFA3
names: Similarity
messages: Belongs to the ModE family.

1249552:PS2015 RS10065
gene id: 1249552:PS2015_RS10065
uniprot id: A0A0S2KE88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1249552:PS2015 RS07515
gene id: 1249552:PS2015_RS07515
uniprot id: A0A0S2KDB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1249552:PS2015 RS10370
gene id: 1249552:PS2015_RS10370
uniprot id: A0A0S2KEF2
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1249552:PS2015 RS03580
gene id: 1249552:PS2015_RS03580
uniprot id: A0A0S2KAS7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1249552:PS2015 RS10810
gene id: 1249552:PS2015_RS10810
uniprot id: A0A0S2KES4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1249552:PS2015 RS03190
gene id: 1249552:PS2015_RS03190
uniprot id: A0A0S2KBF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

1249552:PS2015 RS10365
gene id: 1249552:PS2015_RS10365
uniprot id: A0A0S2KEV7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1249552:PS2015 RS14730
gene id: 1249552:PS2015_RS14730
uniprot id: A0A0S2KGY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1249552:PS2015 RS10390
gene id: 1249552:PS2015_RS10390
uniprot id: A0A0S2KEJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1249552:PS2015 RS07765
gene id: 1249552:PS2015_RS07765
uniprot id: A0A0S2KDQ2
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1249552:PS2015 RS13375
gene id: 1249552:PS2015_RS13375
uniprot id: A0A0S2KG37
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1249552:PS2015 RS04700
gene id: 1249552:PS2015_RS04700
uniprot id: A0A0S2KCB5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1249552:PS2015 RS11490
gene id: 1249552:PS2015_RS11490
uniprot id: A0A0S2KG32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1249552:PS2015 RS10060
gene id: 1249552:PS2015_RS10060
uniprot id: A0A0S2KE95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1249552:PS2015 RS12270
gene id: 1249552:PS2015_RS12270
uniprot id: A0A0S2KFJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1249552:PS2015 RS08600
gene id: 1249552:PS2015_RS08600
uniprot id: A0A0S2KDX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aromatic amine dehydrogenase light chain family.
messages: Periplasm

1249552:PS2015 RS02110
gene id: 1249552:PS2015_RS02110
uniprot id: A0A0S2K9T8
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

1249552:PS2015 RS12150
gene id: 1249552:PS2015_RS12150
uniprot id: A0A0S2KG10
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

1249552:PS2015 RS13325
gene id: 1249552:PS2015_RS13325
uniprot id: A0A0S2KG52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1249552:PS2015 RS11395
gene id: 1249552:PS2015_RS11395
uniprot id: A0A0S2KEY6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1249552:PS2015 RS05590
gene id: 1249552:PS2015_RS05590
uniprot id: A0A0S2KBX5
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

1249552:PS2015 RS10185
gene id: 1249552:PS2015_RS10185
uniprot id: A0A0S2KFE1
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1249552:PS2015 RS07790
gene id: 1249552:PS2015_RS07790
uniprot id: A0A0S2KD97
names: Subcellular Location Annotation
messages: Cytoplasm

1249552:PS2015 RS10820
gene id: 1249552:PS2015_RS10820
uniprot id: A0A0S2KEN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1249552:PS2015 RS00160
gene id: 1249552:PS2015_RS00160
uniprot id: A0A0S2K8Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

1249552:PS2015 RS04350
gene id: 1249552:PS2015_RS04350
uniprot id: A0A0S2KB40
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

1249552:PS2015 RS06775
gene id: 1249552:PS2015_RS06775
uniprot id: A0A0S2KD41
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

1249552:PS2015 RS08895
gene id: 1249552:PS2015_RS08895
uniprot id: A0A0S2KDP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

1249552:PS2015 RS11720
gene id: 1249552:PS2015_RS11720
uniprot id: A0A0S2KF65
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

1249552:PS2015 RS06030
gene id: 1249552:PS2015_RS06030
uniprot id: A0A0S2KCP4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1249552:PS2015 RS11520
gene id: 1249552:PS2015_RS11520
uniprot id: A0A0S2KFH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1249552:PS2015 RS10400
gene id: 1249552:PS2015_RS10400
uniprot id: A0A0S2KEG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1249552:PS2015 RS07415
gene id: 1249552:PS2015_RS07415
uniprot id: A0A0S2KCW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

1249552:PS2015 RS02495
gene id: 1249552:PS2015_RS02495
uniprot id: A0A0S2KA28
names: Similarity
messages: Belongs to the GARS family.

1249552:PS2015 RS00325
gene id: 1249552:PS2015_RS00325
uniprot id: A0A0S2K8V2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1249552:PS2015 RS14850
gene id: 1249552:PS2015_RS14850
uniprot id: A0A0S2KGZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

1249552:PS2015 RS08965
gene id: 1249552:PS2015_RS08965
uniprot id: A0A0S2KEB2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1249552:PS2015 RS12525
gene id: 1249552:PS2015_RS12525
uniprot id: A0A0S2KFP3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1249552:PS2015 RS10680
gene id: 1249552:PS2015_RS10680
uniprot id: A0A0S2KEM1
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1249552:PS2015 RS03585
gene id: 1249552:PS2015_RS03585
uniprot id: A0A0S2KB07
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1249552:PS2015 RS10490
gene id: 1249552:PS2015_RS10490
uniprot id: A0A0S2KFJ0
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

1249552:PS2015 RS14880
gene id: 1249552:PS2015_RS14880
uniprot id: A0A0S2KGX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1249552:PS2015 RS00200
gene id: 1249552:PS2015_RS00200
uniprot id: A0A0S2K9R1
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1249552:PS2015 RS08495
gene id: 1249552:PS2015_RS08495
uniprot id: A0A0S2KDF9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1249552:PS2015 RS02640
gene id: 1249552:PS2015_RS02640
uniprot id: A0A0S2KAV5
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS13515
gene id: 1249552:PS2015_RS13515
uniprot id: A0A0S2KG63
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1249552:PS2015 RS06185
gene id: 1249552:PS2015_RS06185
uniprot id: A0A0S2KD63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

1249552:PS2015 RS07425
gene id: 1249552:PS2015_RS07425
uniprot id: A0A0S2KDG9
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1249552:PS2015 RS06240
gene id: 1249552:PS2015_RS06240
uniprot id: A0A0S2KC56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1249552:PS2015 RS14955
gene id: 1249552:PS2015_RS14955
uniprot id: A0A0S2KH05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoid occlusion factor SlmA family.
messages: Homodimer. Interacts with FtsZ.
messages: Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
messages: nucleoid

1249552:PS2015 RS05100
gene id: 1249552:PS2015_RS05100
uniprot id: A0A0S2KBI8
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1249552:PS2015 RS09545
gene id: 1249552:PS2015_RS09545
uniprot id: A0A0S2KE96
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1249552:PS2015 RS13460
gene id: 1249552:PS2015_RS13460
uniprot id: A0A0S2KG67
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1249552:PS2015 RS06445
gene id: 1249552:PS2015_RS06445
uniprot id: A0A0S2KCX5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1249552:PS2015 RS10405
gene id: 1249552:PS2015_RS10405
uniprot id: A0A0S2KF37
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1249552:PS2015 RS10720
gene id: 1249552:PS2015_RS10720
uniprot id: A0A0S2KEM8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1249552:PS2015 RS08060
gene id: 1249552:PS2015_RS08060
uniprot id: A0A0S2KD75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1249552:PS2015 RS09325
gene id: 1249552:PS2015_RS09325
uniprot id: A0A0S2KEI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1249552:PS2015 RS04040
gene id: 1249552:PS2015_RS04040
uniprot id: A0A0S2KBV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

1249552:PS2015 RS01470
gene id: 1249552:PS2015_RS01470
uniprot id: A0A0S2KAI9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1249552:PS2015 RS02810
gene id: 1249552:PS2015_RS02810
uniprot id: A0A0S2KAZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1249552:PS2015 RS00245
gene id: 1249552:PS2015_RS00245
uniprot id: A0A0S2K8T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

1249552:PS2015 RS07385
gene id: 1249552:PS2015_RS07385
uniprot id: A0A0S2KCV0
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.

1249552:PS2015 RS10905
gene id: 1249552:PS2015_RS10905
uniprot id: A0A0S2KEQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1249552:PS2015 RS05670
gene id: 1249552:PS2015_RS05670
uniprot id: A0A0S2KBW8
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1249552:PS2015 RS07480
gene id: 1249552:PS2015_RS07480
uniprot id: A0A0S2KDG0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1249552:PS2015 RS09835
gene id: 1249552:PS2015_RS09835
uniprot id: A0A0S2KER9
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1249552:PS2015 RS00730
gene id: 1249552:PS2015_RS00730
uniprot id: A0A0S2K960
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1249552:PS2015 RS09485
gene id: 1249552:PS2015_RS09485
uniprot id: A0A0S2KEK1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1249552:PS2015 RS10915
gene id: 1249552:PS2015_RS10915
uniprot id: A0A0S2KET0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1249552:PS2015 RS12340
gene id: 1249552:PS2015_RS12340
uniprot id: A0A0S2KFS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1249552:PS2015 RS11115
gene id: 1249552:PS2015_RS11115
uniprot id: A0A0S2KFA0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1249552:PS2015 RS11600
gene id: 1249552:PS2015_RS11600
uniprot id: A0A0S2KFJ3
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

1249552:PS2015 RS14010
gene id: 1249552:PS2015_RS14010
uniprot id: A0A0S2KGG9
names: Function
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1249552:PS2015 RS08410
gene id: 1249552:PS2015_RS08410
uniprot id: A0A0S2KDE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

1249552:PS2015 RS06295
gene id: 1249552:PS2015_RS06295
uniprot id: A0A0S2KC84
names: Similarity
messages: Belongs to the SufE family.

1249552:PS2015 RS13215
gene id: 1249552:PS2015_RS13215
uniprot id: A0A0S2KH40
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS00515
gene id: 1249552:PS2015_RS00515
uniprot id: A0A0S2K8Y6
names: Similarity
messages: Belongs to the MotB family.

1249552:PS2015 RS00085
gene id: 1249552:PS2015_RS00085
uniprot id: A0A0S2K8P1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1249552:PS2015 RS08560
gene id: 1249552:PS2015_RS08560
uniprot id: A0A0S2KE18
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1249552:PS2015 RS10710
gene id: 1249552:PS2015_RS10710
uniprot id: A0A0S2KEL2
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1249552:PS2015 RS05355
gene id: 1249552:PS2015_RS05355
uniprot id: A0A0S2KCM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1249552:PS2015 RS03870
gene id: 1249552:PS2015_RS03870
uniprot id: A0A0S2KBG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1249552:PS2015 RS08235
gene id: 1249552:PS2015_RS08235
uniprot id: A0A0S2KDA7
names: Similarity
messages: Belongs to the YciI family.

1249552:PS2015 RS11690
gene id: 1249552:PS2015_RS11690
uniprot id: A0A0S2KF35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

1249552:PS2015 RS13770
gene id: 1249552:PS2015_RS13770
uniprot id: A0A0S2KGD6
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1249552:PS2015 RS09830
gene id: 1249552:PS2015_RS09830
uniprot id: A0A0S2KE70
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1249552:PS2015 RS14415
gene id: 1249552:PS2015_RS14415
uniprot id: A0A0S2KGU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1249552:PS2015 RS15360
gene id: 1249552:PS2015_RS15360
uniprot id: A0A0S2KHK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1249552:PS2015 RS03650
gene id: 1249552:PS2015_RS03650
uniprot id: A0A0S2KAR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1249552:PS2015 RS11680
gene id: 1249552:PS2015_RS11680
uniprot id: A0A0S2KFK9
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS10910
gene id: 1249552:PS2015_RS10910
uniprot id: A0A0S2KEP3
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1249552:PS2015 RS14375
gene id: 1249552:PS2015_RS14375
uniprot id: A0A0S2KHR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1249552:PS2015 RS08845
gene id: 1249552:PS2015_RS08845
uniprot id: A0A0S2KDN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BexD/CtrA/VexA family.
messages: Cell outer membrane
messages: Membrane

1249552:PS2015 RS02135
gene id: 1249552:PS2015_RS02135
uniprot id: A0A0S2K9U2
names: Similarity
messages: Belongs to the thioredoxin family.

1249552:PS2015 RS15220
gene id: 1249552:PS2015_RS15220
uniprot id: A0A0S2KHD1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1249552:PS2015 RS10805
gene id: 1249552:PS2015_RS10805
uniprot id: A0A0S2KEX5
names: Similarity
messages: Belongs to the PhoH family.

1249552:PS2015 RS05770
gene id: 1249552:PS2015_RS05770
uniprot id: A0A0S2KCV8
names: Similarity
messages: Belongs to the class-C beta-lactamase family.

1249552:PS2015 RS01915
gene id: 1249552:PS2015_RS01915
uniprot id: A0A0S2KAD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1249552:PS2015 RS04575
gene id: 1249552:PS2015_RS04575
uniprot id: A0A0S2KB86
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

1249552:PS2015 RS10685
gene id: 1249552:PS2015_RS10685
uniprot id: A0A0S2KEM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1249552:PS2015 RS00155
gene id: 1249552:PS2015_RS00155
uniprot id: A0A0S2K920
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1249552:PS2015 RS13530
gene id: 1249552:PS2015_RS13530
uniprot id: A0A0S2KH82
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1249552:PS2015 RS11780
gene id: 1249552:PS2015_RS11780
uniprot id: A0A0S2KF97
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1249552:PS2015 RS02445
gene id: 1249552:PS2015_RS02445
uniprot id: A0A0S2K9Z9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1249552:PS2015 RS04025
gene id: 1249552:PS2015_RS04025
uniprot id: A0A0S2KAY2
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS03285
gene id: 1249552:PS2015_RS03285
uniprot id: A0A0S2KAG9
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1249552:PS2015 RS07470
gene id: 1249552:PS2015_RS07470
uniprot id: A0A0S2KCW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

1249552:PS2015 RS06835
gene id: 1249552:PS2015_RS06835
uniprot id: A0A0S2KDF8
names: Similarity
messages: Belongs to the peptidase M16 family.

1249552:PS2015 RS10940
gene id: 1249552:PS2015_RS10940
uniprot id: A0A0S2KFT0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1249552:PS2015 RS13450
gene id: 1249552:PS2015_RS13450
uniprot id: A0A0S2KH61
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1249552:PS2015 RS02530
gene id: 1249552:PS2015_RS02530
uniprot id: A0A0S2KAT5
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1249552:PS2015 RS06875
gene id: 1249552:PS2015_RS06875
uniprot id: A0A0S2KCJ4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1249552:PS2015 RS13250
gene id: 1249552:PS2015_RS13250
uniprot id: A0A0S2KG99
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

1249552:PS2015 RS08290
gene id: 1249552:PS2015_RS08290
uniprot id: A0A0S2KDC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1249552:PS2015 RS06945
gene id: 1249552:PS2015_RS06945
uniprot id: A0A0S2KCZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1249552:PS2015 RS13385
gene id: 1249552:PS2015_RS13385
uniprot id: A0A0S2KH69
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1249552:PS2015 RS00765
gene id: 1249552:PS2015_RS00765
uniprot id: A0A0S2K942
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1249552:PS2015 RS06820
gene id: 1249552:PS2015_RS06820
uniprot id: A0A0S2KCM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1249552:PS2015 RS15315
gene id: 1249552:PS2015_RS15315
uniprot id: A0A0S2KH76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1249552:PS2015 RS02150
gene id: 1249552:PS2015_RS02150
uniprot id: A0A0S2KAK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1249552:PS2015 RS11455
gene id: 1249552:PS2015_RS11455
uniprot id: A0A0S2KF30
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1249552:PS2015 RS12475
gene id: 1249552:PS2015_RS12475
uniprot id: A0A0S2KG86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1249552:PS2015 RS04630
gene id: 1249552:PS2015_RS04630
uniprot id: A0A0S2KBB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1249552:PS2015 RS03540
gene id: 1249552:PS2015_RS03540
uniprot id: A0A0S2KAK6
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS06175
gene id: 1249552:PS2015_RS06175
uniprot id: A0A0S2KC69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1249552:PS2015 RS14590
gene id: 1249552:PS2015_RS14590
uniprot id: A0A0S2KGU6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

1249552:PS2015 RS03560
gene id: 1249552:PS2015_RS03560
uniprot id: A0A0S2KBC1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1249552:PS2015 RS12350
gene id: 1249552:PS2015_RS12350
uniprot id: A0A0S2KFK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1249552:PS2015 RS02735
gene id: 1249552:PS2015_RS02735
uniprot id: A0A0S2KB03
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1249552:PS2015 RS07460
gene id: 1249552:PS2015_RS07460
uniprot id: A0A0S2KCV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1249552:PS2015 RS10935
gene id: 1249552:PS2015_RS10935
uniprot id: A0A0S2KES5
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1249552:PS2015 RS11445
gene id: 1249552:PS2015_RS11445
uniprot id: A0A0S2KEZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1249552:PS2015 RS09560
gene id: 1249552:PS2015_RS09560
uniprot id: A0A0S2KE09
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1249552:PS2015 RS03520
gene id: 1249552:PS2015_RS03520
uniprot id: A0A0S2KAK7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1249552:PS2015 RS13180
gene id: 1249552:PS2015_RS13180
uniprot id: A0A0S2KG16
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1249552:PS2015 RS11480
gene id: 1249552:PS2015_RS11480
uniprot id: A0A0S2KF41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1249552:PS2015 RS14080
gene id: 1249552:PS2015_RS14080
uniprot id: A0A0S2KGQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1249552:PS2015 RS00150
gene id: 1249552:PS2015_RS00150
uniprot id: A0A0S2K8Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1249552:PS2015 RS11890
gene id: 1249552:PS2015_RS11890
uniprot id: A0A0S2KGB7
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1249552:PS2015 RS02505
gene id: 1249552:PS2015_RS02505
uniprot id: A0A0S2KAG7
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

1249552:PS2015 RS09330
gene id: 1249552:PS2015_RS09330
uniprot id: A0A0S2KEP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1249552:PS2015 RS15275
gene id: 1249552:PS2015_RS15275
uniprot id: A0A0S2KHQ1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1249552:PS2015 RS14470
gene id: 1249552:PS2015_RS14470
uniprot id: A0A0S2KH54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

1249552:PS2015 RS14870
gene id: 1249552:PS2015_RS14870
uniprot id: A0A0S2KHC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1249552:PS2015 RS15310
gene id: 1249552:PS2015_RS15310
uniprot id: A0A0S2KHB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1249552:PS2015 RS00525
gene id: 1249552:PS2015_RS00525
uniprot id: A0A0S2K9X5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1249552:PS2015 RS11335
gene id: 1249552:PS2015_RS11335
uniprot id: A0A0S2KEZ4
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1249552:PS2015 RS00005
gene id: 1249552:PS2015_RS00005
uniprot id: A0A0S2K8N0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1249552:PS2015 RS13885
gene id: 1249552:PS2015_RS13885
uniprot id: A0A0S2KGZ6
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

1249552:PS2015 RS03280
gene id: 1249552:PS2015_RS03280
uniprot id: A0A0S2KAD7
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1249552:PS2015 RS09060
gene id: 1249552:PS2015_RS09060
uniprot id: A0A0S2KEC7
names: Similarity
messages: Belongs to the UPF0434 family.

1249552:PS2015 RS13760
gene id: 1249552:PS2015_RS13760
uniprot id: A0A0S2KGC5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1249552:PS2015 RS06130
gene id: 1249552:PS2015_RS06130
uniprot id: A0A0S2KC50
names: Similarity
messages: Belongs to the PspA/IM30 family.

1249552:PS2015 RS09975
gene id: 1249552:PS2015_RS09975
uniprot id: A0A0S2KEA8
names: Similarity
messages: Belongs to the WrbA family.

1249552:PS2015 RS01640
gene id: 1249552:PS2015_RS01640
uniprot id: A0A0S2KAL8
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1249552:PS2015 RS10410
gene id: 1249552:PS2015_RS10410
uniprot id: A0A0S2KFH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

1249552:PS2015 RS08980
gene id: 1249552:PS2015_RS08980
uniprot id: A0A0S2KDR1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Monomer.

1249552:PS2015 RS08930
gene id: 1249552:PS2015_RS08930
uniprot id: A0A0S2KDQ0
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1249552:PS2015 RS05170
gene id: 1249552:PS2015_RS05170
uniprot id: A0A0S2KBP0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1249552:PS2015 RS15120
gene id: 1249552:PS2015_RS15120
uniprot id: A0A0S2KHG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

1249552:PS2015 RS11320
gene id: 1249552:PS2015_RS11320
uniprot id: A0A0S2KF05
names: Subcellular Location Annotation
messages: Cell inner membrane

1249552:PS2015 RS10585
gene id: 1249552:PS2015_RS10585
uniprot id: A0A0S2KEK9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1249552:PS2015 RS15175
gene id: 1249552:PS2015_RS15175
uniprot id: A0A0S2KH30
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1249552:PS2015 RS05060
gene id: 1249552:PS2015_RS05060
uniprot id: A0A0S2KBY6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1249552:PS2015 RS13330
gene id: 1249552:PS2015_RS13330
uniprot id: A0A0S2KGB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1249552:PS2015 RS12905
gene id: 1249552:PS2015_RS12905
uniprot id: A0A0S2KG91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1249552:PS2015 RS12325
gene id: 1249552:PS2015_RS12325
uniprot id: A0A0S2KFI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1249552:PS2015 RS06930
gene id: 1249552:PS2015_RS06930
uniprot id: A0A0S2KDK8
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1249552:PS2015 RS02620
gene id: 1249552:PS2015_RS02620
uniprot id: A0A0S2KB51
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1249552:PS2015 RS11280
gene id: 1249552:PS2015_RS11280
uniprot id: A0A0S2KFC6
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1249552:PS2015 RS12725
gene id: 1249552:PS2015_RS12725
uniprot id: A0A0S2KFQ7
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

1249552:PS2015 RS12860
gene id: 1249552:PS2015_RS12860
uniprot id: A0A0S2KFT1
names: Similarity
messages: Belongs to the DEAD box helicase family.

1249552:PS2015 RS13200
gene id: 1249552:PS2015_RS13200
uniprot id: A0A0S2KH15
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

1249552:PS2015 RS11530
gene id: 1249552:PS2015_RS11530
uniprot id: A0A0S2KF00
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1249552:PS2015 RS13740
gene id: 1249552:PS2015_RS13740
uniprot id: A0A0S2KG94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1249552:PS2015 RS11475
gene id: 1249552:PS2015_RS11475
uniprot id: A0A0S2KF01
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1249552:PS2015 RS00470
gene id: 1249552:PS2015_RS00470
uniprot id: A0A0S2K8X9
names: Similarity
messages: Belongs to the PhzF family.

1249552:PS2015 RS13835
gene id: 1249552:PS2015_RS13835
uniprot id: A0A0S2KGH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1249552:PS2015 RS04815
gene id: 1249552:PS2015_RS04815
uniprot id: A0A0S2KBV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1249552:PS2015 RS07980
gene id: 1249552:PS2015_RS07980
uniprot id: A0A0S2KD64
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1249552:PS2015 RS08085
gene id: 1249552:PS2015_RS08085
uniprot id: A0A0S2KD80
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1249552:PS2015 RS05940
gene id: 1249552:PS2015_RS05940
uniprot id: A0A0S2KD16
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1249552:PS2015 RS09945
gene id: 1249552:PS2015_RS09945
uniprot id: A0A0S2KF02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

1249552:PS2015 RS04250
gene id: 1249552:PS2015_RS04250
uniprot id: A0A0S2KB55
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

1249552:PS2015 RS13655
gene id: 1249552:PS2015_RS13655
uniprot id: A0A0S2KG92
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS03365
gene id: 1249552:PS2015_RS03365
uniprot id: A0A0S2KAF4
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS04570
gene id: 1249552:PS2015_RS04570
uniprot id: A0A0S2KB95
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

1249552:PS2015 RS15230
gene id: 1249552:PS2015_RS15230
uniprot id: A0A0S2KH60
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS08770
gene id: 1249552:PS2015_RS08770
uniprot id: A0A0S2KDL4
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1249552:PS2015 RS10055
gene id: 1249552:PS2015_RS10055
uniprot id: A0A0S2KEC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

1249552:PS2015 RS04470
gene id: 1249552:PS2015_RS04470
uniprot id: A0A0S2KCB6
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS06555
gene id: 1249552:PS2015_RS06555
uniprot id: A0A0S2KCL7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1249552:PS2015 RS08275
gene id: 1249552:PS2015_RS08275
uniprot id: A0A0S2KDP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

1249552:PS2015 RS15355
gene id: 1249552:PS2015_RS15355
uniprot id: A0A0S2KHS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1249552:PS2015 RS11130
gene id: 1249552:PS2015_RS11130
uniprot id: A0A0S2KEW5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1249552:PS2015 RS03790
gene id: 1249552:PS2015_RS03790
uniprot id: A0A0S2KBR6
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1249552:PS2015 RS10550
gene id: 1249552:PS2015_RS10550
uniprot id: A0A0S2KEJ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

1249552:PS2015 RS05190
gene id: 1249552:PS2015_RS05190
uniprot id: A0A0S2KC38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1249552:PS2015 RS13735
gene id: 1249552:PS2015_RS13735
uniprot id: A0A0S2KGB2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

1249552:PS2015 RS04640
gene id: 1249552:PS2015_RS04640
uniprot id: A0A0S2KBV4
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1249552:PS2015 RS01660
gene id: 1249552:PS2015_RS01660
uniprot id: A0A0S2KAD8
names: Similarity
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.

1249552:PS2015 RS14535
gene id: 1249552:PS2015_RS14535
uniprot id: A0A0S2KHV4
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1249552:PS2015 RS09000
gene id: 1249552:PS2015_RS09000
uniprot id: A0A0S2KE69
names: Similarity
messages: Belongs to the pirin family.

1249552:PS2015 RS13420
gene id: 1249552:PS2015_RS13420
uniprot id: A0A0S2KGC9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1249552:PS2015 RS14060
gene id: 1249552:PS2015_RS14060
uniprot id: A0A0S2KGH3
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

1249552:PS2015 RS11620
gene id: 1249552:PS2015_RS11620
uniprot id: A0A0S2KFC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1249552:PS2015 RS02655
gene id: 1249552:PS2015_RS02655
uniprot id: A0A0S2KA88
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

1249552:PS2015 RS06080
gene id: 1249552:PS2015_RS06080
uniprot id: A0A0S2KC58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1249552:PS2015 RS13365
gene id: 1249552:PS2015_RS13365
uniprot id: A0A0S2KGQ7
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1249552:PS2015 RS07735
gene id: 1249552:PS2015_RS07735
uniprot id: A0A0S2KDK7
names: Caution
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

1249552:PS2015 RS04380
gene id: 1249552:PS2015_RS04380
uniprot id: A0A0S2KB63
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1249552:PS2015 RS12335
gene id: 1249552:PS2015_RS12335
uniprot id: A0A0S2KFL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1249552:PS2015 RS11710
gene id: 1249552:PS2015_RS11710
uniprot id: A0A0S2KFA1
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1249552:PS2015 RS01665
gene id: 1249552:PS2015_RS01665
uniprot id: A0A0S2KAF0
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

1249552:PS2015 RS00775
gene id: 1249552:PS2015_RS00775
uniprot id: A0A0S2K9V8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

1249552:PS2015 RS04540
gene id: 1249552:PS2015_RS04540
uniprot id: A0A0S2KB94
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS01685
gene id: 1249552:PS2015_RS01685
uniprot id: A0A0S2K9V2
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS00080
gene id: 1249552:PS2015_RS00080
uniprot id: A0A0S2K8N8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

1249552:PS2015 RS00100
gene id: 1249552:PS2015_RS00100
uniprot id: A0A0S2K9D4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1249552:PS2015 RS07660
gene id: 1249552:PS2015_RS07660
uniprot id: A0A0S2KD09
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS02085
gene id: 1249552:PS2015_RS02085
uniprot id: A0A0S2K9S9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1249552:PS2015 RS06190
gene id: 1249552:PS2015_RS06190
uniprot id: A0A0S2KCS9
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1249552:PS2015 RS10090
gene id: 1249552:PS2015_RS10090
uniprot id: A0A0S2KEB6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1249552:PS2015 RS04045
gene id: 1249552:PS2015_RS04045
uniprot id: A0A0S2KAW9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

1249552:PS2015 RS06965
gene id: 1249552:PS2015_RS06965
uniprot id: A0A0S2KCT4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1249552:PS2015 RS09275
gene id: 1249552:PS2015_RS09275
uniprot id: A0A0S2KE43
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1249552:PS2015 RS03615
gene id: 1249552:PS2015_RS03615
uniprot id: A0A0S2KBN7
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1249552:PS2015 RS11995
gene id: 1249552:PS2015_RS11995
uniprot id: A0A0S2KG66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

1249552:PS2015 RS00440
gene id: 1249552:PS2015_RS00440
uniprot id: A0A0S2K8X5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1249552:PS2015 RS03260
gene id: 1249552:PS2015_RS03260
uniprot id: A0A0S2KAE2
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1249552:PS2015 RS05195
gene id: 1249552:PS2015_RS05195
uniprot id: A0A0S2KCK4
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1249552:PS2015 RS04990
gene id: 1249552:PS2015_RS04990
uniprot id: A0A0S2KBK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1249552:PS2015 RS13315
gene id: 1249552:PS2015_RS13315
uniprot id: A0A0S2KG31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1249552:PS2015 RS11905
gene id: 1249552:PS2015_RS11905
uniprot id: A0A0S2KGD1
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS04905
gene id: 1249552:PS2015_RS04905
uniprot id: A0A0S2KBR8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1249552:PS2015 RS04100
gene id: 1249552:PS2015_RS04100
uniprot id: A0A0S2KAZ7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1249552:PS2015 RS07825
gene id: 1249552:PS2015_RS07825
uniprot id: A0A0S2KDZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell membrane
messages: Cytoplasm

1249552:PS2015 RS06210
gene id: 1249552:PS2015_RS06210
uniprot id: A0A0S2KC60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1249552:PS2015 RS02290
gene id: 1249552:PS2015_RS02290
uniprot id: A0A0S2KAQ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1249552:PS2015 RS15195
gene id: 1249552:PS2015_RS15195
uniprot id: A0A0S2KHY6
names: Similarity
messages: Belongs to the RutC family.

1249552:PS2015 RS00195
gene id: 1249552:PS2015_RS00195
uniprot id: A0A0S2K8S9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1249552:PS2015 RS13440
gene id: 1249552:PS2015_RS13440
uniprot id: A0A0S2KG74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1249552:PS2015 RS13990
gene id: 1249552:PS2015_RS13990
uniprot id: A0A0S2KGI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1249552:PS2015 RS00040
gene id: 1249552:PS2015_RS00040
uniprot id: A0A0S2K9M4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1249552:PS2015 RS02590
gene id: 1249552:PS2015_RS02590
uniprot id: A0A0S2KAH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1249552:PS2015 RS03785
gene id: 1249552:PS2015_RS03785
uniprot id: A0A0S2KBF1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1249552:PS2015 RS13395
gene id: 1249552:PS2015_RS13395
uniprot id: A0A0S2KGZ0
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1249552:PS2015 RS15285
gene id: 1249552:PS2015_RS15285
uniprot id: A0A0S2KHJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1249552:PS2015 RS05685
gene id: 1249552:PS2015_RS05685
uniprot id: A0A0S2KCI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm

1249552:PS2015 RS03515
gene id: 1249552:PS2015_RS03515
uniprot id: A0A0S2KAM5
names: Function
names: Subunit
messages: Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein.
messages: Monomer in both c-di-GMP-bound and free forms.

1249552:PS2015 RS05820
gene id: 1249552:PS2015_RS05820
uniprot id: A0A0S2KBY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1249552:PS2015 RS01925
gene id: 1249552:PS2015_RS01925
uniprot id: A0A0S2K9Q5
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

1249552:PS2015 RS11255
gene id: 1249552:PS2015_RS11255
uniprot id: A0A0S2KEY4
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS00455
gene id: 1249552:PS2015_RS00455
uniprot id: A0A0S2K9S7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1249552:PS2015 RS02260
gene id: 1249552:PS2015_RS02260
uniprot id: A0A0S2KA52
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1249552:PS2015 RS03620
gene id: 1249552:PS2015_RS03620
uniprot id: A0A0S2KAM2
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

1249552:PS2015 RS09215
gene id: 1249552:PS2015_RS09215
uniprot id: A0A0S2KDX0
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS04600
gene id: 1249552:PS2015_RS04600
uniprot id: A0A0S2KB90
names: Similarity
messages: Belongs to the CIA30 family.

1249552:PS2015 RS12235
gene id: 1249552:PS2015_RS12235
uniprot id: A0A0S2KGA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1249552:PS2015 RS03430
gene id: 1249552:PS2015_RS03430
uniprot id: A0A0S2KAK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1249552:PS2015 RS07420
gene id: 1249552:PS2015_RS07420
uniprot id: A0A0S2KDU2
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1249552:PS2015 RS01745
gene id: 1249552:PS2015_RS01745
uniprot id: A0A0S2KAG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1249552:PS2015 RS07090
gene id: 1249552:PS2015_RS07090
uniprot id: A0A0S2KDN9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
messages: Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1249552:PS2015 RS08265
gene id: 1249552:PS2015_RS08265
uniprot id: A0A0S2KDW6
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

1249552:PS2015 RS14555
gene id: 1249552:PS2015_RS14555
uniprot id: A0A0S2KGR7
names: Similarity
messages: Belongs to the UPF0235 family.

1249552:PS2015 RS00140
gene id: 1249552:PS2015_RS00140
uniprot id: A0A0S2K8Q9
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS00505
gene id: 1249552:PS2015_RS00505
uniprot id: A0A0S2K9P4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

1249552:PS2015 RS07485
gene id: 1249552:PS2015_RS07485
uniprot id: A0A0S2KDT7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1249552:PS2015 RS01900
gene id: 1249552:PS2015_RS01900
uniprot id: A0A0S2KAS3
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1249552:PS2015 RS04615
gene id: 1249552:PS2015_RS04615
uniprot id: A0A0S2KBT6
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

1249552:PS2015 RS03635
gene id: 1249552:PS2015_RS03635
uniprot id: A0A0S2KBC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

1249552:PS2015 RS06910
gene id: 1249552:PS2015_RS06910
uniprot id: A0A0S2KD57
names: Similarity
messages: Belongs to the Skp family.

1249552:PS2015 RS02940
gene id: 1249552:PS2015_RS02940
uniprot id: A0A0S2KA76
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1249552:PS2015 RS05600
gene id: 1249552:PS2015_RS05600
uniprot id: A0A0S2KCS8
names: Similarity
messages: Belongs to the pirin family.

1249552:PS2015 RS02670
gene id: 1249552:PS2015_RS02670
uniprot id: A0A0S2KAB1
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

1249552:PS2015 RS07700
gene id: 1249552:PS2015_RS07700
uniprot id: A0A0S2KD08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1249552:PS2015 RS03600
gene id: 1249552:PS2015_RS03600
uniprot id: A0A0S2KAM4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1249552:PS2015 RS12980
gene id: 1249552:PS2015_RS12980
uniprot id: A0A0S2KGH2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1249552:PS2015 RS04520
gene id: 1249552:PS2015_RS04520
uniprot id: A0A0S2KB69
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1249552:PS2015 RS00270
gene id: 1249552:PS2015_RS00270
uniprot id: A0A0S2K8U2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1249552:PS2015 RS12490
gene id: 1249552:PS2015_RS12490
uniprot id: A0A0S2KFM6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

1249552:PS2015 RS05555
gene id: 1249552:PS2015_RS05555
uniprot id: A0A0S2KBS8
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS02265
gene id: 1249552:PS2015_RS02265
uniprot id: A0A0S2KAD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1249552:PS2015 RS08210
gene id: 1249552:PS2015_RS08210
uniprot id: A0A0S2KDA3
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1249552:PS2015 RS11985
gene id: 1249552:PS2015_RS11985
uniprot id: A0A0S2KGF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

1249552:PS2015 RS04050
gene id: 1249552:PS2015_RS04050
uniprot id: A0A0S2KAX4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1249552:PS2015 RS11795
gene id: 1249552:PS2015_RS11795
uniprot id: A0A0S2KF87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

1249552:PS2015 RS06365
gene id: 1249552:PS2015_RS06365
uniprot id: A0A0S2KCX6
names: Similarity
messages: Belongs to the RutC family.

1249552:PS2015 RS13235
gene id: 1249552:PS2015_RS13235
uniprot id: A0A0S2KG14
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

1249552:PS2015 RS14930
gene id: 1249552:PS2015_RS14930
uniprot id: A0A0S2KH04
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1249552:PS2015 RS09970
gene id: 1249552:PS2015_RS09970
uniprot id: A0A0S2KEH1
names: Similarity
messages: Belongs to the ArsC family.

1249552:PS2015 RS00265
gene id: 1249552:PS2015_RS00265
uniprot id: A0A0S2K9T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

1249552:PS2015 RS02795
gene id: 1249552:PS2015_RS02795
uniprot id: A0A0S2KA53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1249552:PS2015 RS10020
gene id: 1249552:PS2015_RS10020
uniprot id: A0A0S2KEV4
names: Similarity
names: Subunit
messages: Belongs to the FliD family.
messages: Homopentamer.

1249552:PS2015 RS09570
gene id: 1249552:PS2015_RS09570
uniprot id: A0A0S2KEL3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1249552:PS2015 RS05080
gene id: 1249552:PS2015_RS05080
uniprot id: A0A0S2KBL8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1249552:PS2015 RS06265
gene id: 1249552:PS2015_RS06265
uniprot id: A0A0S2KC67
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1249552:PS2015 RS12275
gene id: 1249552:PS2015_RS12275
uniprot id: A0A0S2KFH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1249552:PS2015 RS11610
gene id: 1249552:PS2015_RS11610
uniprot id: A0A0S2KF16
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1249552:PS2015 RS06710
gene id: 1249552:PS2015_RS06710
uniprot id: A0A0S2KCF4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1249552:PS2015 RS07890
gene id: 1249552:PS2015_RS07890
uniprot id: A0A0S2KD46
names: Similarity
messages: Belongs to the ArsC family.

1249552:PS2015 RS11935
gene id: 1249552:PS2015_RS11935
uniprot id: A0A0S2KFC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1249552:PS2015 RS04450
gene id: 1249552:PS2015_RS04450
uniprot id: A0A0S2KBS0
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

1249552:PS2015 RS06770
gene id: 1249552:PS2015_RS06770
uniprot id: A0A0S2KDH9
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1249552:PS2015 RS02270
gene id: 1249552:PS2015_RS02270
uniprot id: A0A0S2KA13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1249552:PS2015 RS02300
gene id: 1249552:PS2015_RS02300
uniprot id: A0A0S2K9X3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1249552:PS2015 RS05240
gene id: 1249552:PS2015_RS05240
uniprot id: A0A0S2KBP1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1249552:PS2015 RS14895
gene id: 1249552:PS2015_RS14895
uniprot id: A0A0S2KH39
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

1249552:PS2015 RS05595
gene id: 1249552:PS2015_RS05595
uniprot id: A0A0S2KCI1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1249552:PS2015 RS07960
gene id: 1249552:PS2015_RS07960
uniprot id: A0A0S2KDD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1249552:PS2015 RS12730
gene id: 1249552:PS2015_RS12730
uniprot id: A0A0S2KFS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1249552:PS2015 RS11800
gene id: 1249552:PS2015_RS11800
uniprot id: A0A0S2KF79
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

1249552:PS2015 RS09170
gene id: 1249552:PS2015_RS09170
uniprot id: A0A0S2KEM3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1249552:PS2015 RS10655
gene id: 1249552:PS2015_RS10655
uniprot id: A0A0S2KEL1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

1249552:PS2015 RS11845
gene id: 1249552:PS2015_RS11845
uniprot id: A0A0S2KF78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1249552:PS2015 RS04895
gene id: 1249552:PS2015_RS04895
uniprot id: A0A0S2KBE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TamA family.
messages: Cell outer membrane
messages: Membrane

1249552:PS2015 RS04920
gene id: 1249552:PS2015_RS04920
uniprot id: A0A0S2KBF0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1249552:PS2015 RS13660
gene id: 1249552:PS2015_RS13660
uniprot id: A0A0S2KG80
names: Similarity
messages: Belongs to the UPF0178 family.

1249552:PS2015 RS02440
gene id: 1249552:PS2015_RS02440
uniprot id: A0A0S2KA03
names: Similarity
messages: Belongs to the glutamine synthetase family.

1249552:PS2015 RS14710
gene id: 1249552:PS2015_RS14710
uniprot id: A0A0S2KHQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1249552:PS2015 RS09040
gene id: 1249552:PS2015_RS09040
uniprot id: A0A0S2KDT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1249552:PS2015 RS10440
gene id: 1249552:PS2015_RS10440
uniprot id: A0A0S2KEX2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1249552:PS2015 RS12545
gene id: 1249552:PS2015_RS12545
uniprot id: A0A0S2KFM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1249552:PS2015 RS01750
gene id: 1249552:PS2015_RS01750
uniprot id: A0A0S2KA95
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1249552:PS2015 RS07785
gene id: 1249552:PS2015_RS07785
uniprot id: A0A0S2KD27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1249552:PS2015 RS12890
gene id: 1249552:PS2015_RS12890
uniprot id: A0A0S2KGX6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

1249552:PS2015 RS14980
gene id: 1249552:PS2015_RS14980
uniprot id: A0A0S2KH12
names: Function
names: Subunit
messages: Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins.
messages: Homodimer.

1249552:PS2015 RS07710
gene id: 1249552:PS2015_RS07710
uniprot id: A0A0S2KD07
names: Similarity
messages: Belongs to the DsrF/TusC family.

1249552:PS2015 RS06485
gene id: 1249552:PS2015_RS06485
uniprot id: A0A0S2KCA9
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

1249552:PS2015 RS14830
gene id: 1249552:PS2015_RS14830
uniprot id: A0A0S2KGZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1249552:PS2015 RS07775
gene id: 1249552:PS2015_RS07775
uniprot id: A0A0S2KD22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1249552:PS2015 RS03210
gene id: 1249552:PS2015_RS03210
uniprot id: A0A0S2KB50
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1249552:PS2015 RS03810
gene id: 1249552:PS2015_RS03810
uniprot id: A0A0S2KBF9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1249552:PS2015 RS02125
gene id: 1249552:PS2015_RS02125
uniprot id: A0A0S2KAL9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

1249552:PS2015 RS08470
gene id: 1249552:PS2015_RS08470
uniprot id: A0A0S2KDF5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1249552:PS2015 RS12790
gene id: 1249552:PS2015_RS12790
uniprot id: A0A0S2KGE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1249552:PS2015 RS01145
gene id: 1249552:PS2015_RS01145
uniprot id: A0A0S2KA15
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1249552:PS2015 RS10050
gene id: 1249552:PS2015_RS10050
uniprot id: A0A0S2KEI5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1249552:PS2015 RS05480
gene id: 1249552:PS2015_RS05480
uniprot id: A0A0S2KBR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1249552:PS2015 RS13190
gene id: 1249552:PS2015_RS13190
uniprot id: A0A0S2KG18
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1249552:PS2015 RS00050
gene id: 1249552:PS2015_RS00050
uniprot id: A0A0S2K9J0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

1249552:PS2015 RS04385
gene id: 1249552:PS2015_RS04385
uniprot id: A0A0S2KC97
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1249552:PS2015 RS08620
gene id: 1249552:PS2015_RS08620
uniprot id: A0A0S2KDP9
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1249552:PS2015 RS11535
gene id: 1249552:PS2015_RS11535
uniprot id: A0A0S2KF45
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.

1249552:PS2015 RS07565
gene id: 1249552:PS2015_RS07565
uniprot id: A0A0S2KDV2
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1249552:PS2015 RS15280
gene id: 1249552:PS2015_RS15280
uniprot id: A0A0S2KHZ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

1249552:PS2015 RS08400
gene id: 1249552:PS2015_RS08400
uniprot id: A0A0S2KDY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1249552:PS2015 RS14725
gene id: 1249552:PS2015_RS14725
uniprot id: A0A0S2KGU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1249552:PS2015 RS02580
gene id: 1249552:PS2015_RS02580
uniprot id: A0A0S2KA96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1249552:PS2015 RS00755
gene id: 1249552:PS2015_RS00755
uniprot id: A0A0S2KA57
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1249552:PS2015 RS11835
gene id: 1249552:PS2015_RS11835
uniprot id: A0A0S2KG35
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1249552:PS2015 RS00460
gene id: 1249552:PS2015_RS00460
uniprot id: A0A0S2K9C9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1249552:PS2015 RS01535
gene id: 1249552:PS2015_RS01535
uniprot id: A0A0S2K9H5
names: PTM
messages: Binds 1 heme group per subunit.

1249552:PS2015 RS06335
gene id: 1249552:PS2015_RS06335
uniprot id: A0A0S2KCU7
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1249552:PS2015 RS02305
gene id: 1249552:PS2015_RS02305
uniprot id: A0A0S2K9Z8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1249552:PS2015 RS15170
gene id: 1249552:PS2015_RS15170
uniprot id: A0A0S2KI54
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

1249552:PS2015 RS03640
gene id: 1249552:PS2015_RS03640
uniprot id: A0A0S2KBD2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1249552:PS2015 RS00590
gene id: 1249552:PS2015_RS00590
uniprot id: A0A0S2KA10
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1249552:PS2015 RS05490
gene id: 1249552:PS2015_RS05490
uniprot id: A0A0S2KC29
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1249552:PS2015 RS07150
gene id: 1249552:PS2015_RS07150
uniprot id: A0A0S2KDA4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1249552:PS2015 RS00390
gene id: 1249552:PS2015_RS00390
uniprot id: A0A0S2K937
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

1249552:PS2015 RS11840
gene id: 1249552:PS2015_RS11840
uniprot id: A0A0S2KFP1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1249552:PS2015 RS15225
gene id: 1249552:PS2015_RS15225
uniprot id: A0A0S2KHA3
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1249552:PS2015 RS00810
gene id: 1249552:PS2015_RS00810
uniprot id: A0A0S2K986
names: Similarity
messages: Belongs to the glutamate synthase family.

1249552:PS2015 RS12405
gene id: 1249552:PS2015_RS12405
uniprot id: A0A0S2KG58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1249552:PS2015 RS08735
gene id: 1249552:PS2015_RS08735
uniprot id: A0A0S2KDL5
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS08615
gene id: 1249552:PS2015_RS08615
uniprot id: A0A0S2KDJ0
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1249552:PS2015 RS02625
gene id: 1249552:PS2015_RS02625
uniprot id: A0A0S2KA22
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS07810
gene id: 1249552:PS2015_RS07810
uniprot id: A0A0S2KD30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1249552:PS2015 RS07745
gene id: 1249552:PS2015_RS07745
uniprot id: A0A0S2KD19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1249552:PS2015 RS07455
gene id: 1249552:PS2015_RS07455
uniprot id: A0A0S2KD35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1249552:PS2015 RS13890
gene id: 1249552:PS2015_RS13890
uniprot id: A0A0S2KH89
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

1249552:PS2015 RS09345
gene id: 1249552:PS2015_RS09345
uniprot id: A0A0S2KDX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1249552:PS2015 RS09540
gene id: 1249552:PS2015_RS09540
uniprot id: A0A0S2KE27
names: Similarity
messages: Belongs to the peptidase M18 family.

1249552:PS2015 RS15000
gene id: 1249552:PS2015_RS15000
uniprot id: A0A0S2KH26
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1249552:PS2015 RS07100
gene id: 1249552:PS2015_RS07100
uniprot id: A0A0S2KDD5
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

1249552:PS2015 RS07740
gene id: 1249552:PS2015_RS07740
uniprot id: A0A0S2KDY6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1249552:PS2015 RS08990
gene id: 1249552:PS2015_RS08990
uniprot id: A0A0S2KED3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).

1249552:PS2015 RS13040
gene id: 1249552:PS2015_RS13040
uniprot id: A0A0S2KGY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1249552:PS2015 RS08010
gene id: 1249552:PS2015_RS08010
uniprot id: A0A0S2KDR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1249552:PS2015 RS13585
gene id: 1249552:PS2015_RS13585
uniprot id: A0A0S2KGD7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1249552:PS2015 RS13120
gene id: 1249552:PS2015_RS13120
uniprot id: A0A0S2KH00
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

1249552:PS2015 RS07010
gene id: 1249552:PS2015_RS07010
uniprot id: A0A0S2KDM2
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1249552:PS2015 RS11290
gene id: 1249552:PS2015_RS11290
uniprot id: A0A0S2KEW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1249552:PS2015 RS07540
gene id: 1249552:PS2015_RS07540
uniprot id: A0A0S2KCX3
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1249552:PS2015 RS00110
gene id: 1249552:PS2015_RS00110
uniprot id: A0A0S2K8R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1249552:PS2015 RS01530
gene id: 1249552:PS2015_RS01530
uniprot id: A0A0S2K9P3
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

1249552:PS2015 RS13880
gene id: 1249552:PS2015_RS13880
uniprot id: A0A0S2KHH3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1249552:PS2015 RS15250
gene id: 1249552:PS2015_RS15250
uniprot id: A0A0S2KI71
names: Similarity
messages: Belongs to the UPF0246 family.

1249552:PS2015 RS04405
gene id: 1249552:PS2015_RS04405
uniprot id: A0A0S2KBL0
names: Similarity
messages: Belongs to the CopC family.

1249552:PS2015 RS09210
gene id: 1249552:PS2015_RS09210
uniprot id: A0A0S2KDU7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1249552:PS2015 RS08150
gene id: 1249552:PS2015_RS08150
uniprot id: A0A0S2KDA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1249552:PS2015 RS07145
gene id: 1249552:PS2015_RS07145
uniprot id: A0A0S2KCQ2
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1249552:PS2015 RS09360
gene id: 1249552:PS2015_RS09360
uniprot id: A0A0S2KE63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1249552:PS2015 RS09895
gene id: 1249552:PS2015_RS09895
uniprot id: A0A0S2KE94
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1249552:PS2015 RS09930
gene id: 1249552:PS2015_RS09930
uniprot id: A0A0S2KE83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1249552:PS2015 RS13355
gene id: 1249552:PS2015_RS13355
uniprot id: A0A0S2KG27
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1249552:PS2015 RS10865
gene id: 1249552:PS2015_RS10865
uniprot id: A0A0S2KFJ2
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS02985
gene id: 1249552:PS2015_RS02985
uniprot id: A0A0S2KAE1
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS14335
gene id: 1249552:PS2015_RS14335
uniprot id: A0A0S2KGN9
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

1249552:PS2015 RS13185
gene id: 1249552:PS2015_RS13185
uniprot id: A0A0S2KFZ8
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS00275
gene id: 1249552:PS2015_RS00275
uniprot id: A0A0S2K8T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1249552:PS2015 RS07265
gene id: 1249552:PS2015_RS07265
uniprot id: A0A0S2KCS1
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1249552:PS2015 RS10945
gene id: 1249552:PS2015_RS10945
uniprot id: A0A0S2KFD5
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

1249552:PS2015 RS13230
gene id: 1249552:PS2015_RS13230
uniprot id: A0A0S2KGF4
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1249552:PS2015 RS01195
gene id: 1249552:PS2015_RS01195
uniprot id: A0A0S2K9C3
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1249552:PS2015 RS00020
gene id: 1249552:PS2015_RS00020
uniprot id: A0A0S2K9B7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1249552:PS2015 RS08485
gene id: 1249552:PS2015_RS08485
uniprot id: A0A0S2KEE9
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

1249552:PS2015 RS13050
gene id: 1249552:PS2015_RS13050
uniprot id: A0A0S2KFZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1249552:PS2015 RS01480
gene id: 1249552:PS2015_RS01480
uniprot id: A0A0S2K9H2
names: Similarity
messages: Belongs to the UPF0145 family.

1249552:PS2015 RS09050
gene id: 1249552:PS2015_RS09050
uniprot id: A0A0S2KDS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1249552:PS2015 RS05215
gene id: 1249552:PS2015_RS05215
uniprot id: A0A0S2KCA0
names: Similarity
messages: Belongs to the P(II) protein family.

1249552:PS2015 RS14540
gene id: 1249552:PS2015_RS14540
uniprot id: A0A0S2KHC2
names: Similarity
messages: Belongs to the asparaginase 1 family.

1249552:PS2015 RS06870
gene id: 1249552:PS2015_RS06870
uniprot id: A0A0S2KCJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1249552:PS2015 RS11525
gene id: 1249552:PS2015_RS11525
uniprot id: A0A0S2KF15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1249552:PS2015 RS03740
gene id: 1249552:PS2015_RS03740
uniprot id: A0A0S2KAS4
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1249552:PS2015 RS07910
gene id: 1249552:PS2015_RS07910
uniprot id: A0A0S2KE16
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

1249552:PS2015 RS06050
gene id: 1249552:PS2015_RS06050
uniprot id: A0A0S2KC21
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1249552:PS2015 RS03010
gene id: 1249552:PS2015_RS03010
uniprot id: A0A0S2KA83
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

1249552:PS2015 RS13800
gene id: 1249552:PS2015_RS13800
uniprot id: A0A0S2KGY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1249552:PS2015 RS02555
gene id: 1249552:PS2015_RS02555
uniprot id: A0A0S2KAT3
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

1249552:PS2015 RS15305
gene id: 1249552:PS2015_RS15305
uniprot id: A0A0S2KHE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1249552:PS2015 RS05065
gene id: 1249552:PS2015_RS05065
uniprot id: A0A0S2KBI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

1249552:PS2015 RS10240
gene id: 1249552:PS2015_RS10240
uniprot id: A0A0S2KEC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1249552:PS2015 RS00430
gene id: 1249552:PS2015_RS00430
uniprot id: A0A0S2K9W5
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1249552:PS2015 RS09465
gene id: 1249552:PS2015_RS09465
uniprot id: A0A0S2KE15
names: Similarity
messages: Belongs to the peptidase M1 family.

1249552:PS2015 RS12180
gene id: 1249552:PS2015_RS12180
uniprot id: A0A0S2KFP7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1249552:PS2015 RS13700
gene id: 1249552:PS2015_RS13700
uniprot id: A0A0S2KHB5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1249552:PS2015 RS11570
gene id: 1249552:PS2015_RS11570
uniprot id: A0A0S2KG54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1249552:PS2015 RS10085
gene id: 1249552:PS2015_RS10085
uniprot id: A0A0S2KEB7
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1249552:PS2015 RS02565
gene id: 1249552:PS2015_RS02565
uniprot id: A0A0S2KAP4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1249552:PS2015 RS04900
gene id: 1249552:PS2015_RS04900
uniprot id: A0A0S2KBI6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1249552:PS2015 RS09150
gene id: 1249552:PS2015_RS09150
uniprot id: A0A0S2KDU4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1249552:PS2015 RS06840
gene id: 1249552:PS2015_RS06840
uniprot id: A0A0S2KCG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

1249552:PS2015 RS00610
gene id: 1249552:PS2015_RS00610
uniprot id: A0A0S2K9S4
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1249552:PS2015 RS05695
gene id: 1249552:PS2015_RS05695
uniprot id: A0A0S2KBZ8
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

1249552:PS2015 RS04165
gene id: 1249552:PS2015_RS04165
uniprot id: A0A0S2KB05
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1249552:PS2015 RS12330
gene id: 1249552:PS2015_RS12330
uniprot id: A0A0S2KFH3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1249552:PS2015 RS11135
gene id: 1249552:PS2015_RS11135
uniprot id: A0A0S2KF43
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1249552:PS2015 RS06915
gene id: 1249552:PS2015_RS06915
uniprot id: A0A0S2KDH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1249552:PS2015 RS13400
gene id: 1249552:PS2015_RS13400
uniprot id: A0A0S2KGJ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1249552:PS2015 RS13490
gene id: 1249552:PS2015_RS13490
uniprot id: A0A0S2KG48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

1249552:PS2015 RS10555
gene id: 1249552:PS2015_RS10555
uniprot id: A0A0S2KEI9
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1249552:PS2015 RS10770
gene id: 1249552:PS2015_RS10770
uniprot id: A0A0S2KFP8
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS00175
gene id: 1249552:PS2015_RS00175
uniprot id: A0A0S2K8U5
names: Similarity
messages: Belongs to the SCO1/2 family.

1249552:PS2015 RS08950
gene id: 1249552:PS2015_RS08950
uniprot id: A0A0S2KDQ3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1249552:PS2015 RS07065
gene id: 1249552:PS2015_RS07065
uniprot id: A0A0S2KCN1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

1249552:PS2015 RS07270
gene id: 1249552:PS2015_RS07270
uniprot id: A0A0S2KCS6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

1249552:PS2015 RS12200
gene id: 1249552:PS2015_RS12200
uniprot id: A0A0S2KFH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1249552:PS2015 RS08985
gene id: 1249552:PS2015_RS08985
uniprot id: A0A0S2KES7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Monomer.

1249552:PS2015 RS06670
gene id: 1249552:PS2015_RS06670
uniprot id: A0A0S2KD12
names: Subcellular Location Annotation
messages: Cytoplasm

1249552:PS2015 RS00660
gene id: 1249552:PS2015_RS00660
uniprot id: A0A0S2K916
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1249552:PS2015 RS00490
gene id: 1249552:PS2015_RS00490
uniprot id: A0A0S2K8Y0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1249552:PS2015 RS09520
gene id: 1249552:PS2015_RS09520
uniprot id: A0A0S2KES9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1249552:PS2015 RS07025
gene id: 1249552:PS2015_RS07025
uniprot id: A0A0S2KD13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1249552:PS2015 RS06905
gene id: 1249552:PS2015_RS06905
uniprot id: A0A0S2KCJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1249552:PS2015 RS10445
gene id: 1249552:PS2015_RS10445
uniprot id: A0A0S2KEG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1249552:PS2015 RS13795
gene id: 1249552:PS2015_RS13795
uniprot id: A0A0S2KHF5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1249552:PS2015 RS08815
gene id: 1249552:PS2015_RS08815
uniprot id: A0A0S2KDM4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1249552:PS2015 RS13750
gene id: 1249552:PS2015_RS13750
uniprot id: A0A0S2KGI7
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

1249552:PS2015 RS02030
gene id: 1249552:PS2015_RS02030
uniprot id: A0A0S2K9S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1249552:PS2015 RS10250
gene id: 1249552:PS2015_RS10250
uniprot id: A0A0S2KF08
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1249552:PS2015 RS13680
gene id: 1249552:PS2015_RS13680
uniprot id: A0A0S2KGB4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1249552:PS2015 RS11025
gene id: 1249552:PS2015_RS11025
uniprot id: A0A0S2KFF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1249552:PS2015 RS11505
gene id: 1249552:PS2015_RS11505
uniprot id: A0A0S2KG46
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1249552:PS2015 RS05510
gene id: 1249552:PS2015_RS05510
uniprot id: A0A0S2KBW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1249552:PS2015 RS12320
gene id: 1249552:PS2015_RS12320
uniprot id: A0A0S2KFY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1249552:PS2015 RS12260
gene id: 1249552:PS2015_RS12260
uniprot id: A0A0S2KFR1
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1249552:PS2015 RS10465
gene id: 1249552:PS2015_RS10465
uniprot id: A0A0S2KEL0
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

1249552:PS2015 RS00090
gene id: 1249552:PS2015_RS00090
uniprot id: A0A0S2K8N5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1249552:PS2015 RS03165
gene id: 1249552:PS2015_RS03165
uniprot id: A0A0S2KAH3
names: Function
names: Subunit
messages: Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins.
messages: Homodimer.

1249552:PS2015 RS03925
gene id: 1249552:PS2015_RS03925
uniprot id: A0A0S2KB58
names: Similarity
messages: Belongs to the TPP enzyme family.

1249552:PS2015 RS12220
gene id: 1249552:PS2015_RS12220
uniprot id: A0A0S2KFI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1249552:PS2015 RS10095
gene id: 1249552:PS2015_RS10095
uniprot id: A0A0S2KFC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1249552:PS2015 RS12315
gene id: 1249552:PS2015_RS12315
uniprot id: A0A0S2KGC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1249552:PS2015 RS04515
gene id: 1249552:PS2015_RS04515
uniprot id: A0A0S2KB74
names: Similarity
messages: Belongs to the peptidase M16 family.

1249552:PS2015 RS08535
gene id: 1249552:PS2015_RS08535
uniprot id: A0A0S2KDP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

1249552:PS2015 RS00790
gene id: 1249552:PS2015_RS00790
uniprot id: A0A0S2K956
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1249552:PS2015 RS06090
gene id: 1249552:PS2015_RS06090
uniprot id: A0A0S2KD25
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1249552:PS2015 RS08355
gene id: 1249552:PS2015_RS08355
uniprot id: A0A0S2KDR5
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

1249552:PS2015 RS08080
gene id: 1249552:PS2015_RS08080
uniprot id: A0A0S2KD82
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1249552:PS2015 RS15095
gene id: 1249552:PS2015_RS15095
uniprot id: A0A0S2KH14
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1249552:PS2015 RS04155
gene id: 1249552:PS2015_RS04155
uniprot id: A0A0S2KBH3
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1249552:PS2015 RS09495
gene id: 1249552:PS2015_RS09495
uniprot id: A0A0S2KE04
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

1249552:PS2015 RS01755
gene id: 1249552:PS2015_RS01755
uniprot id: A0A0S2K9M9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

1249552:PS2015 RS09095
gene id: 1249552:PS2015_RS09095
uniprot id: A0A0S2KE84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

1249552:PS2015 RS06390
gene id: 1249552:PS2015_RS06390
uniprot id: A0A0S2KCH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

1249552:PS2015 RS08385
gene id: 1249552:PS2015_RS08385
uniprot id: A0A0S2KDE0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

1249552:PS2015 RS06825
gene id: 1249552:PS2015_RS06825
uniprot id: A0A0S2KCI5
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

1249552:PS2015 RS14680
gene id: 1249552:PS2015_RS14680
uniprot id: A0A0S2KHG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1249552:PS2015 RS04720
gene id: 1249552:PS2015_RS04720
uniprot id: A0A0S2KBW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1249552:PS2015 RS11705
gene id: 1249552:PS2015_RS11705
uniprot id: A0A0S2KFE4
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

1249552:PS2015 RS12300
gene id: 1249552:PS2015_RS12300
uniprot id: A0A0S2KFJ5
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1249552:PS2015 RS09425
gene id: 1249552:PS2015_RS09425
uniprot id: A0A0S2KF11
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1249552:PS2015 RS08090
gene id: 1249552:PS2015_RS08090
uniprot id: A0A0S2KE71
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1249552:PS2015 RS06200
gene id: 1249552:PS2015_RS06200
uniprot id: A0A0S2KCJ7
names: Similarity
messages: Belongs to the RecJ family.

1249552:PS2015 RS05540
gene id: 1249552:PS2015_RS05540
uniprot id: A0A0S2KCF1
names: Similarity
messages: Belongs to the GST superfamily.

1249552:PS2015 RS01730
gene id: 1249552:PS2015_RS01730
uniprot id: A0A0S2K9M5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1249552:PS2015 RS08335
gene id: 1249552:PS2015_RS08335
uniprot id: A0A0S2KDC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

1249552:PS2015 RS11295
gene id: 1249552:PS2015_RS11295
uniprot id: A0A0S2KEZ8
names: Similarity
messages: Belongs to the MotB family.

1249552:PS2015 RS06035
gene id: 1249552:PS2015_RS06035
uniprot id: A0A0S2KCQ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1249552:PS2015 RS12540
gene id: 1249552:PS2015_RS12540
uniprot id: A0A0S2KFN9
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1249552:PS2015 RS11500
gene id: 1249552:PS2015_RS11500
uniprot id: A0A0S2KF39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1249552:PS2015 RS00680
gene id: 1249552:PS2015_RS00680
uniprot id: A0A0S2K926
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1249552:PS2015 RS02550
gene id: 1249552:PS2015_RS02550
uniprot id: A0A0S2KB75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

1249552:PS2015 RS03765
gene id: 1249552:PS2015_RS03765
uniprot id: A0A0S2KAV2
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1249552:PS2015 RS10570
gene id: 1249552:PS2015_RS10570
uniprot id: A0A0S2KFK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1249552:PS2015 RS00305
gene id: 1249552:PS2015_RS00305
uniprot id: A0A0S2K8V0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1249552:PS2015 RS15070
gene id: 1249552:PS2015_RS15070
uniprot id: A0A0S2KH28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1249552:PS2015 RS07760
gene id: 1249552:PS2015_RS07760
uniprot id: A0A0S2KDM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

1249552:PS2015 RS12205
gene id: 1249552:PS2015_RS12205
uniprot id: A0A0S2KG33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1249552:PS2015 RS00530
gene id: 1249552:PS2015_RS00530
uniprot id: A0A0S2K9Q9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1249552:PS2015 RS08250
gene id: 1249552:PS2015_RS08250
uniprot id: A0A0S2KDB2
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

1249552:PS2015 RS01675
gene id: 1249552:PS2015_RS01675
uniprot id: A0A0S2K9L6
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS09045
gene id: 1249552:PS2015_RS09045
uniprot id: A0A0S2KDS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1249552:PS2015 RS08155
gene id: 1249552:PS2015_RS08155
uniprot id: A0A0S2KD91
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1249552:PS2015 RS12195
gene id: 1249552:PS2015_RS12195
uniprot id: A0A0S2KFG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1249552:PS2015 RS12010
gene id: 1249552:PS2015_RS12010
uniprot id: A0A0S2KFA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

1249552:PS2015 RS06320
gene id: 1249552:PS2015_RS06320
uniprot id: A0A0S2KC88
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1249552:PS2015 RS06505
gene id: 1249552:PS2015_RS06505
uniprot id: A0A0S2KD92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

1249552:PS2015 RS10615
gene id: 1249552:PS2015_RS10615
uniprot id: A0A0S2KEJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

1249552:PS2015 RS09335
gene id: 1249552:PS2015_RS09335
uniprot id: A0A0S2KEC5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1249552:PS2015 RS11885
gene id: 1249552:PS2015_RS11885
uniprot id: A0A0S2KFW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1249552:PS2015 RS15165
gene id: 1249552:PS2015_RS15165
uniprot id: A0A0S2KHQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SelU family.
messages: Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
messages: Monomer.

1249552:PS2015 RS11830
gene id: 1249552:PS2015_RS11830
uniprot id: A0A0S2KFU7
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1249552:PS2015 RS05070
gene id: 1249552:PS2015_RS05070
uniprot id: A0A0S2KBH6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1249552:PS2015 RS04090
gene id: 1249552:PS2015_RS04090
uniprot id: A0A0S2KB27
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1249552:PS2015 RS14350
gene id: 1249552:PS2015_RS14350
uniprot id: A0A0S2KGP8
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS01040
gene id: 1249552:PS2015_RS01040
uniprot id: A0A0S2K9K4
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1249552:PS2015 RS00850
gene id: 1249552:PS2015_RS00850
uniprot id: A0A0S2KA40
names: Similarity
messages: Belongs to the Gfa family.

1249552:PS2015 RS02545
gene id: 1249552:PS2015_RS02545
uniprot id: A0A0S2KA29
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1249552:PS2015 RS11015
gene id: 1249552:PS2015_RS11015
uniprot id: A0A0S2KET9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1249552:PS2015 RS03200
gene id: 1249552:PS2015_RS03200
uniprot id: A0A0S2KAE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1249552:PS2015 RS04305
gene id: 1249552:PS2015_RS04305
uniprot id: A0A0S2KBP6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1249552:PS2015 RS11330
gene id: 1249552:PS2015_RS11330
uniprot id: A0A0S2KFZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1249552:PS2015 RS10425
gene id: 1249552:PS2015_RS10425
uniprot id: A0A0S2KFI6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1249552:PS2015 RS12985
gene id: 1249552:PS2015_RS12985
uniprot id: A0A0S2KGR3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1249552:PS2015 RS01605
gene id: 1249552:PS2015_RS01605
uniprot id: A0A0S2K9T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S49 family.
messages: Cell inner membrane

1249552:PS2015 RS10535
gene id: 1249552:PS2015_RS10535
uniprot id: A0A0S2KEJ7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1249552:PS2015 RS08295
gene id: 1249552:PS2015_RS08295
uniprot id: A0A0S2KDJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1249552:PS2015 RS13000
gene id: 1249552:PS2015_RS13000
uniprot id: A0A0S2KFV8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1249552:PS2015 RS11550
gene id: 1249552:PS2015_RS11550
uniprot id: A0A0S2KF34
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1249552:PS2015 RS03330
gene id: 1249552:PS2015_RS03330
uniprot id: A0A0S2KAN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

1249552:PS2015 RS01545
gene id: 1249552:PS2015_RS01545
uniprot id: A0A0S2K9L1
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

1249552:PS2015 RS02000
gene id: 1249552:PS2015_RS02000
uniprot id: A0A0S2KAJ5
names: Similarity
messages: Belongs to the MipA/OmpV family.

1249552:PS2015 RS05530
gene id: 1249552:PS2015_RS05530
uniprot id: A0A0S2KBS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane

1249552:PS2015 RS06660
gene id: 1249552:PS2015_RS06660
uniprot id: A0A0S2KCI0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1249552:PS2015 RS11980
gene id: 1249552:PS2015_RS11980
uniprot id: A0A0S2KFD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

1249552:PS2015 RS14095
gene id: 1249552:PS2015_RS14095
uniprot id: A0A0S2KGI2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. PqqE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
messages: Interacts with PqqD. The interaction is necessary for activity of PqqE.

1249552:PS2015 RS07300
gene id: 1249552:PS2015_RS07300
uniprot id: A0A0S2KCT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1249552:PS2015 RS10605
gene id: 1249552:PS2015_RS10605
uniprot id: A0A0S2KF03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcdB/MmdB/OadB family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

1249552:PS2015 RS03770
gene id: 1249552:PS2015_RS03770
uniprot id: A0A0S2KAS1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.

1249552:PS2015 RS09480
gene id: 1249552:PS2015_RS09480
uniprot id: A0A0S2KE14
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS06955
gene id: 1249552:PS2015_RS06955
uniprot id: A0A0S2KCL8
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1249552:PS2015 RS10360
gene id: 1249552:PS2015_RS10360
uniprot id: A0A0S2KF92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

1249552:PS2015 RS03935
gene id: 1249552:PS2015_RS03935
uniprot id: A0A0S2KAW1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1249552:PS2015 RS13495
gene id: 1249552:PS2015_RS13495
uniprot id: A0A0S2KG84
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1249552:PS2015 RS02460
gene id: 1249552:PS2015_RS02460
uniprot id: A0A0S2K9Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1249552:PS2015 RS14950
gene id: 1249552:PS2015_RS14950
uniprot id: A0A0S2KHD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1249552:PS2015 RS12855
gene id: 1249552:PS2015_RS12855
uniprot id: A0A0S2KFU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1249552:PS2015 RS06755
gene id: 1249552:PS2015_RS06755
uniprot id: A0A0S2KDE4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1249552:PS2015 RS07235
gene id: 1249552:PS2015_RS07235
uniprot id: A0A0S2KDP4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1249552:PS2015 RS02760
gene id: 1249552:PS2015_RS02760
uniprot id: A0A0S2KAK8
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1249552:PS2015 RS01710
gene id: 1249552:PS2015_RS01710
uniprot id: A0A0S2K9N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1249552:PS2015 RS03435
gene id: 1249552:PS2015_RS03435
uniprot id: A0A0S2KB87
names: Similarity
messages: Belongs to the GSP E family.

1249552:PS2015 RS06885
gene id: 1249552:PS2015_RS06885
uniprot id: A0A0S2KCR7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1249552:PS2015 RS14685
gene id: 1249552:PS2015_RS14685
uniprot id: A0A0S2KHV0
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

1249552:PS2015 RS11430
gene id: 1249552:PS2015_RS11430
uniprot id: A0A0S2KFM0
names: Similarity
messages: Belongs to the GSP E family.

1249552:PS2015 RS02215
gene id: 1249552:PS2015_RS02215
uniprot id: A0A0S2K9V5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1249552:PS2015 RS13060
gene id: 1249552:PS2015_RS13060
uniprot id: A0A0S2KGJ0
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1249552:PS2015 RS08070
gene id: 1249552:PS2015_RS08070
uniprot id: A0A0S2KDS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1249552:PS2015 RS07195
gene id: 1249552:PS2015_RS07195
uniprot id: A0A0S2KCR1
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS06380
gene id: 1249552:PS2015_RS06380
uniprot id: A0A0S2KC90
names: Similarity
messages: Belongs to the CIA30 family.

1249552:PS2015 RS03370
gene id: 1249552:PS2015_RS03370
uniprot id: A0A0S2KAI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

1249552:PS2015 RS00780
gene id: 1249552:PS2015_RS00780
uniprot id: A0A0S2K9Z4
names: Similarity
messages: Belongs to the YggT family.

1249552:PS2015 RS00210
gene id: 1249552:PS2015_RS00210
uniprot id: A0A0S2K9M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

1249552:PS2015 RS07580
gene id: 1249552:PS2015_RS07580
uniprot id: A0A0S2KCZ5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1249552:PS2015 RS02520
gene id: 1249552:PS2015_RS02520
uniprot id: A0A0S2KA07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1249552:PS2015 RS13810
gene id: 1249552:PS2015_RS13810
uniprot id: A0A0S2KGS6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1249552:PS2015 RS15235
gene id: 1249552:PS2015_RS15235
uniprot id: A0A0S2KH57
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1249552:PS2015 RS00510
gene id: 1249552:PS2015_RS00510
uniprot id: A0A0S2KA01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1249552:PS2015 RS00060
gene id: 1249552:PS2015_RS00060
uniprot id: A0A0S2K8P5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1249552:PS2015 RS10875
gene id: 1249552:PS2015_RS10875
uniprot id: A0A0S2KEP6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1249552:PS2015 RS13075
gene id: 1249552:PS2015_RS13075
uniprot id: A0A0S2KFY8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1249552:PS2015 RS13070
gene id: 1249552:PS2015_RS13070
uniprot id: A0A0S2KGC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1249552:PS2015 RS07860
gene id: 1249552:PS2015_RS07860
uniprot id: A0A0S2KD36
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1249552:PS2015 RS09270
gene id: 1249552:PS2015_RS09270
uniprot id: A0A0S2KDX6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1249552:PS2015 RS11155
gene id: 1249552:PS2015_RS11155
uniprot id: A0A0S2KEX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1249552:PS2015 RS00115
gene id: 1249552:PS2015_RS00115
uniprot id: A0A0S2K8R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

1249552:PS2015 RS11825
gene id: 1249552:PS2015_RS11825
uniprot id: A0A0S2KGA8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1249552:PS2015 RS00310
gene id: 1249552:PS2015_RS00310
uniprot id: A0A0S2K924
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1249552:PS2015 RS06095
gene id: 1249552:PS2015_RS06095
uniprot id: A0A0S2KC61
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1249552:PS2015 RS15160
gene id: 1249552:PS2015_RS15160
uniprot id: A0A0S2KH59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1249552:PS2015 RS10420
gene id: 1249552:PS2015_RS10420
uniprot id: A0A0S2KEH8
names: Similarity
messages: Belongs to the Dps family.

1249552:PS2015 RS03625
gene id: 1249552:PS2015_RS03625
uniprot id: A0A0S2KAN2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

1249552:PS2015 RS13035
gene id: 1249552:PS2015_RS13035
uniprot id: A0A0S2KGJ1
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1249552:PS2015 RS10670
gene id: 1249552:PS2015_RS10670
uniprot id: A0A0S2KF82
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1249552:PS2015 RS13470
gene id: 1249552:PS2015_RS13470
uniprot id: A0A0S2KGR5
names: Similarity
messages: Belongs to the bacterial secretin family.

1249552:PS2015 RS14915
gene id: 1249552:PS2015_RS14915
uniprot id: A0A0S2KHL4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
messages: Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1249552:PS2015 RS15345
gene id: 1249552:PS2015_RS15345
uniprot id: A0A0S2KH84
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1249552:PS2015 RS02105
gene id: 1249552:PS2015_RS02105
uniprot id: A0A0S2K9Y7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1249552:PS2015 RS00010
gene id: 1249552:PS2015_RS00010
uniprot id: A0A0S2K8M8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1249552:PS2015 RS14670
gene id: 1249552:PS2015_RS14670
uniprot id: A0A0S2KGT9
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS12845
gene id: 1249552:PS2015_RS12845
uniprot id: A0A0S2KG23
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS11160
gene id: 1249552:PS2015_RS11160
uniprot id: A0A0S2KFH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

1249552:PS2015 RS09940
gene id: 1249552:PS2015_RS09940
uniprot id: A0A0S2KEU6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1249552:PS2015 RS11975
gene id: 1249552:PS2015_RS11975
uniprot id: A0A0S2KFB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP L family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

1249552:PS2015 RS11990
gene id: 1249552:PS2015_RS11990
uniprot id: A0A0S2KFX8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

1249552:PS2015 RS14385
gene id: 1249552:PS2015_RS14385
uniprot id: A0A0S2KHJ1
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS06850
gene id: 1249552:PS2015_RS06850
uniprot id: A0A0S2KDJ6
names: Similarity
messages: Belongs to the BolA/IbaG family.

1249552:PS2015 RS11355
gene id: 1249552:PS2015_RS11355
uniprot id: A0A0S2KFT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1249552:PS2015 RS01350
gene id: 1249552:PS2015_RS01350
uniprot id: A0A0S2K9F0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

1249552:PS2015 RS07445
gene id: 1249552:PS2015_RS07445
uniprot id: A0A0S2KCV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1249552:PS2015 RS02990
gene id: 1249552:PS2015_RS02990
uniprot id: A0A0S2KAC0
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1249552:PS2015 RS11370
gene id: 1249552:PS2015_RS11370
uniprot id: A0A0S2KEX3
names: Similarity
messages: Belongs to the UPF0234 family.

1249552:PS2015 RS05055
gene id: 1249552:PS2015_RS05055
uniprot id: A0A0S2KC75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1249552:PS2015 RS14205
gene id: 1249552:PS2015_RS14205
uniprot id: A0A0S2KHM2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1249552:PS2015 RS13030
gene id: 1249552:PS2015_RS13030
uniprot id: A0A0S2KFY9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1249552:PS2015 RS13150
gene id: 1249552:PS2015_RS13150
uniprot id: A0A0S2KGD8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1249552:PS2015 RS13520
gene id: 1249552:PS2015_RS13520
uniprot id: A0A0S2KG90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1249552:PS2015 RS00595
gene id: 1249552:PS2015_RS00595
uniprot id: A0A0S2K905
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

1249552:PS2015 RS00450
gene id: 1249552:PS2015_RS00450
uniprot id: A0A0S2K9N9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1249552:PS2015 RS14050
gene id: 1249552:PS2015_RS14050
uniprot id: A0A0S2KHD0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1249552:PS2015 RS06250
gene id: 1249552:PS2015_RS06250
uniprot id: A0A0S2KCS5
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1249552:PS2015 RS05790
gene id: 1249552:PS2015_RS05790
uniprot id: A0A0S2KCI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

1249552:PS2015 RS13910
gene id: 1249552:PS2015_RS13910
uniprot id: A0A0S2KGG8
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

1249552:PS2015 RS09900
gene id: 1249552:PS2015_RS09900
uniprot id: A0A0S2KE61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

1249552:PS2015 RS04800
gene id: 1249552:PS2015_RS04800
uniprot id: A0A0S2KCG8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1249552:PS2015 RS09965
gene id: 1249552:PS2015_RS09965
uniprot id: A0A0S2KEA1
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS03185
gene id: 1249552:PS2015_RS03185
uniprot id: A0A0S2KB42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1249552:PS2015 RS13730
gene id: 1249552:PS2015_RS13730
uniprot id: A0A0S2KGQ6
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

1249552:PS2015 RS02755
gene id: 1249552:PS2015_RS02755
uniprot id: A0A0S2KAC8
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1249552:PS2015 RS10695
gene id: 1249552:PS2015_RS10695
uniprot id: A0A0S2KF86
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1249552:PS2015 RS06225
gene id: 1249552:PS2015_RS06225
uniprot id: A0A0S2KC72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1249552:PS2015 RS05295
gene id: 1249552:PS2015_RS05295
uniprot id: A0A0S2KCP0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

1249552:PS2015 RS08020
gene id: 1249552:PS2015_RS08020
uniprot id: A0A0S2KDK5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1249552:PS2015 RS13745
gene id: 1249552:PS2015_RS13745
uniprot id: A0A0S2KGD5
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

1249552:PS2015 RS14460
gene id: 1249552:PS2015_RS14460
uniprot id: A0A0S2KHA9
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1249552:PS2015 RS03195
gene id: 1249552:PS2015_RS03195
uniprot id: A0A0S2KAC2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1249552:PS2015 RS01595
gene id: 1249552:PS2015_RS01595
uniprot id: A0A0S2K9K9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1249552:PS2015 RS10260
gene id: 1249552:PS2015_RS10260
uniprot id: A0A0S2KEE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

1249552:PS2015 RS09420
gene id: 1249552:PS2015_RS09420
uniprot id: A0A0S2KDY9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1249552:PS2015 RS06280
gene id: 1249552:PS2015_RS06280
uniprot id: A0A0S2KCW1
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1249552:PS2015 RS06765
gene id: 1249552:PS2015_RS06765
uniprot id: A0A0S2KCG7
names: Similarity
messages: Belongs to the GSP E family.

1249552:PS2015 RS10735
gene id: 1249552:PS2015_RS10735
uniprot id: A0A0S2KEM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1249552:PS2015 RS12880
gene id: 1249552:PS2015_RS12880
uniprot id: A0A0S2KGV6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

1249552:PS2015 RS03290
gene id: 1249552:PS2015_RS03290
uniprot id: A0A0S2KBN4
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS07955
gene id: 1249552:PS2015_RS07955
uniprot id: A0A0S2KD60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1249552:PS2015 RS13430
gene id: 1249552:PS2015_RS13430
uniprot id: A0A0S2KG62
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1249552:PS2015 RS12265
gene id: 1249552:PS2015_RS12265
uniprot id: A0A0S2KFM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1249552:PS2015 RS00475
gene id: 1249552:PS2015_RS00475
uniprot id: A0A0S2K952
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1249552:PS2015 RS03050
gene id: 1249552:PS2015_RS03050
uniprot id: A0A0S2KB38
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1249552:PS2015 RS04335
gene id: 1249552:PS2015_RS04335
uniprot id: A0A0S2KB71
names: Function
names: Similarity
messages: Belongs to the DadA oxidoreductase family.
messages: Oxidative deamination of D-amino acids.

1249552:PS2015 RS08285
gene id: 1249552:PS2015_RS08285
uniprot id: A0A0S2KDC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1249552:PS2015 RS06475
gene id: 1249552:PS2015_RS06475
uniprot id: A0A0S2KCK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1249552:PS2015 RS11925
gene id: 1249552:PS2015_RS11925
uniprot id: A0A0S2KF94
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1249552:PS2015 RS00120
gene id: 1249552:PS2015_RS00120
uniprot id: A0A0S2K9N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Membrane

1249552:PS2015 RS06970
gene id: 1249552:PS2015_RS06970
uniprot id: A0A0S2KCN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1249552:PS2015 RS15365
gene id: 1249552:PS2015_RS15365
uniprot id: A0A0S2KH81
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1249552:PS2015 RS04065
gene id: 1249552:PS2015_RS04065
uniprot id: A0A0S2KBM0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1249552:PS2015 RS13710
gene id: 1249552:PS2015_RS13710
uniprot id: A0A0S2KGB0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1249552:PS2015 RS11645
gene id: 1249552:PS2015_RS11645
uniprot id: A0A0S2KFS6
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1249552:PS2015 RS01975
gene id: 1249552:PS2015_RS01975
uniprot id: A0A0S2KAS9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1249552:PS2015 RS07315
gene id: 1249552:PS2015_RS07315
uniprot id: A0A0S2KDD9
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

1249552:PS2015 RS02720
gene id: 1249552:PS2015_RS02720
uniprot id: A0A0S2KA59
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1249552:PS2015 RS01390
gene id: 1249552:PS2015_RS01390
uniprot id: A0A0S2KAF5
names: Similarity
messages: Belongs to the peptidase M17 family.

1249552:PS2015 RS09355
gene id: 1249552:PS2015_RS09355
uniprot id: A0A0S2KDZ5
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1249552:PS2015 RS09020
gene id: 1249552:PS2015_RS09020
uniprot id: A0A0S2KE02
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1249552:PS2015 RS11580
gene id: 1249552:PS2015_RS11580
uniprot id: A0A0S2KF57
names: Similarity
messages: Belongs to the UPF0102 family.

1249552:PS2015 RS02470
gene id: 1249552:PS2015_RS02470
uniprot id: A0A0S2KB59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1249552:PS2015 RS02455
gene id: 1249552:PS2015_RS02455
uniprot id: A0A0S2KB28
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1249552:PS2015 RS08130
gene id: 1249552:PS2015_RS08130
uniprot id: A0A0S2KD86
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS04105
gene id: 1249552:PS2015_RS04105
uniprot id: A0A0S2KAZ3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1249552:PS2015 RS09935
gene id: 1249552:PS2015_RS09935
uniprot id: A0A0S2KF93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1249552:PS2015 RS06350
gene id: 1249552:PS2015_RS06350
uniprot id: A0A0S2KC73
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1249552:PS2015 RS05840
gene id: 1249552:PS2015_RS05840
uniprot id: A0A0S2KBY5
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS02560
gene id: 1249552:PS2015_RS02560
uniprot id: A0A0S2KAX7
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1249552:PS2015 RS04200
gene id: 1249552:PS2015_RS04200
uniprot id: A0A0S2KBN2
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1249552:PS2015 RS07965
gene id: 1249552:PS2015_RS07965
uniprot id: A0A0S2KD55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1249552:PS2015 RS09265
gene id: 1249552:PS2015_RS09265
uniprot id: A0A0S2KDV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1249552:PS2015 RS07400
gene id: 1249552:PS2015_RS07400
uniprot id: A0A0S2KDF1
names: Similarity
messages: Belongs to the citrate synthase family.

1249552:PS2015 RS10080
gene id: 1249552:PS2015_RS10080
uniprot id: A0A0S2KFB0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1249552:PS2015 RS07075
gene id: 1249552:PS2015_RS07075
uniprot id: A0A0S2KDL6
names: Similarity
messages: Belongs to the UPF0270 family.

1249552:PS2015 RS10860
gene id: 1249552:PS2015_RS10860
uniprot id: A0A0S2KFC1
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1249552:PS2015 RS07815
gene id: 1249552:PS2015_RS07815
uniprot id: A0A0S2KD31
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

1249552:PS2015 RS04055
gene id: 1249552:PS2015_RS04055
uniprot id: A0A0S2KC19
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1249552:PS2015 RS15350
gene id: 1249552:PS2015_RS15350
uniprot id: A0A0S2KI96
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1249552:PS2015 RS05250
gene id: 1249552:PS2015_RS05250
uniprot id: A0A0S2KBQ5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1249552:PS2015 RS08375
gene id: 1249552:PS2015_RS08375
uniprot id: A0A0S2KDL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1249552:PS2015 RS06580
gene id: 1249552:PS2015_RS06580
uniprot id: A0A0S2KCC2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1249552:PS2015 RS00750
gene id: 1249552:PS2015_RS00750
uniprot id: A0A0S2K9U4
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

1249552:PS2015 RS13010
gene id: 1249552:PS2015_RS13010
uniprot id: A0A0S2KG50
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1249552:PS2015 RS01305
gene id: 1249552:PS2015_RS01305
uniprot id: A0A0S2KA41
names: Similarity
messages: Belongs to the CcdB toxin family.

1249552:PS2015 RS10075
gene id: 1249552:PS2015_RS10075
uniprot id: A0A0S2KEW7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of five rings (E,L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1249552:PS2015 RS14835
gene id: 1249552:PS2015_RS14835
uniprot id: A0A0S2KHJ6
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

1249552:PS2015 RS00075
gene id: 1249552:PS2015_RS00075
uniprot id: A0A0S2K907
names: Similarity
messages: Belongs to the DprA/Smf family.

1249552:PS2015 RS00485
gene id: 1249552:PS2015_RS00485
uniprot id: A0A0S2K910
names: Subcellular Location Annotation
messages: Cytoplasm

1249552:PS2015 RS01840
gene id: 1249552:PS2015_RS01840
uniprot id: A0A0S2K9N8
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.

1249552:PS2015 RS10825
gene id: 1249552:PS2015_RS10825
uniprot id: A0A0S2KER5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

1249552:PS2015 RS08180
gene id: 1249552:PS2015_RS08180
uniprot id: A0A0S2KDA1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1249552:PS2015 RS09120
gene id: 1249552:PS2015_RS09120
uniprot id: A0A0S2KDT3
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1249552:PS2015 RS08945
gene id: 1249552:PS2015_RS08945
uniprot id: A0A0S2KDQ8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1249552:PS2015 RS02480
gene id: 1249552:PS2015_RS02480
uniprot id: A0A0S2KAV6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1249552:PS2015 RS09320
gene id: 1249552:PS2015_RS09320
uniprot id: A0A0S2KEZ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

1249552:PS2015 RS10000
gene id: 1249552:PS2015_RS10000
uniprot id: A0A0S2KF96
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1249552:PS2015 RS08575
gene id: 1249552:PS2015_RS08575
uniprot id: A0A0S2KDI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1249552:PS2015 RS11970
gene id: 1249552:PS2015_RS11970
uniprot id: A0A0S2KGD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP M family.
messages: Cell inner membrane
messages: Membrane

1249552:PS2015 RS06160
gene id: 1249552:PS2015_RS06160
uniprot id: A0A0S2KC65
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1249552:PS2015 RS12735
gene id: 1249552:PS2015_RS12735
uniprot id: A0A0S2KGT2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1249552:PS2015 RS03460
gene id: 1249552:PS2015_RS03460
uniprot id: A0A0S2KB93
names: PTM
names: Similarity
messages: Belongs to the photoactive yellow protein family.
messages: The 4-hydroxycinnamic acid (p-coumaric acid) chromophore is covalently bound via a thioester linkage.

1249552:PS2015 RS03055
gene id: 1249552:PS2015_RS03055
uniprot id: A0A0S2KAX1
names: Similarity
messages: Belongs to the peptidase U62 family.

1249552:PS2015 RS10600
gene id: 1249552:PS2015_RS10600
uniprot id: A0A0S2KFE0
names: Similarity
messages: Belongs to the PhoH family.

1249552:PS2015 RS00500
gene id: 1249552:PS2015_RS00500
uniprot id: A0A0S2K903
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

1249552:PS2015 RS09580
gene id: 1249552:PS2015_RS09580
uniprot id: A0A0S2KE26
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1249552:PS2015 RS07230
gene id: 1249552:PS2015_RS07230
uniprot id: A0A0S2KDB6
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

1249552:PS2015 RS04680
gene id: 1249552:PS2015_RS04680
uniprot id: A0A0S2KBA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

1249552:PS2015 RS07205
gene id: 1249552:PS2015_RS07205
uniprot id: A0A0S2KCY6
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS09300
gene id: 1249552:PS2015_RS09300
uniprot id: A0A0S2KEH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1249552:PS2015 RS06275
gene id: 1249552:PS2015_RS06275
uniprot id: A0A0S2KCU3
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1249552:PS2015 RS06925
gene id: 1249552:PS2015_RS06925
uniprot id: A0A0S2KCK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1249552:PS2015 RS01970
gene id: 1249552:PS2015_RS01970
uniprot id: A0A0S2KAI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1249552:PS2015 RS12565
gene id: 1249552:PS2015_RS12565
uniprot id: A0A0S2KFM7
names: Similarity
messages: Belongs to the Fur family.

1249552:PS2015 RS07935
gene id: 1249552:PS2015_RS07935
uniprot id: A0A0S2KDT2
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

1249552:PS2015 RS01845
gene id: 1249552:PS2015_RS01845
uniprot id: A0A0S2K9R9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1249552:PS2015 RS01690
gene id: 1249552:PS2015_RS01690
uniprot id: A0A0S2K9X7
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS01320
gene id: 1249552:PS2015_RS01320
uniprot id: A0A0S2K9E0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1249552:PS2015 RS08370
gene id: 1249552:PS2015_RS08370
uniprot id: A0A0S2KDF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1249552:PS2015 RS08645
gene id: 1249552:PS2015_RS08645
uniprot id: A0A0S2KE36
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1249552:PS2015 RS07440
gene id: 1249552:PS2015_RS07440
uniprot id: A0A0S2KCV2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1249552:PS2015 RS08595
gene id: 1249552:PS2015_RS08595
uniprot id: A0A0S2KE73
names: Function
names: Subcellular Location Annotation
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

1249552:PS2015 RS02960
gene id: 1249552:PS2015_RS02960
uniprot id: A0A0S2KAA3
names: Similarity
messages: Belongs to the peptidase S45 family.

1249552:PS2015 RS12510
gene id: 1249552:PS2015_RS12510
uniprot id: A0A0S2KG13
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1249552:PS2015 RS01445
gene id: 1249552:PS2015_RS01445
uniprot id: A0A0S2K9K7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1249552:PS2015 RS09055
gene id: 1249552:PS2015_RS09055
uniprot id: A0A0S2KDU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1249552:PS2015 RS08380
gene id: 1249552:PS2015_RS08380
uniprot id: A0A0S2KDD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

1249552:PS2015 RS08125
gene id: 1249552:PS2015_RS08125
uniprot id: A0A0S2KD87
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1249552:PS2015 RS13020
gene id: 1249552:PS2015_RS13020
uniprot id: A0A0S2KFY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.
messages: Cell membrane
messages: K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels.

1249552:PS2015 RS06170
gene id: 1249552:PS2015_RS06170
uniprot id: A0A0S2KD39
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1249552:PS2015 RS06575
gene id: 1249552:PS2015_RS06575
uniprot id: A0A0S2KCH0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1249552:PS2015 RS01035
gene id: 1249552:PS2015_RS01035
uniprot id: A0A0S2K9I0
names: Similarity
messages: Belongs to the YoeB family.

1249552:PS2015 RS03270
gene id: 1249552:PS2015_RS03270
uniprot id: A0A0S2KB56
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS01400
gene id: 1249552:PS2015_RS01400
uniprot id: A0A0S2K9F6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1249552:PS2015 RS12485
gene id: 1249552:PS2015_RS12485
uniprot id: A0A0S2KFL1
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

1249552:PS2015 RS06165
gene id: 1249552:PS2015_RS06165
uniprot id: A0A0S2KCR3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1249552:PS2015 RS10355
gene id: 1249552:PS2015_RS10355
uniprot id: A0A0S2KF22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1249552:PS2015 RS14110
gene id: 1249552:PS2015_RS14110
uniprot id: A0A0S2KHI7
names: Function
names: Similarity
messages: Belongs to the PqqB family.
messages: May be involved in the transport of PQQ or its precursor to the periplasm.

1249552:PS2015 RS03815
gene id: 1249552:PS2015_RS03815
uniprot id: A0A0S2KBG1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1249552:PS2015 RS13570
gene id: 1249552:PS2015_RS13570
uniprot id: A0A0S2KG61
names: Similarity
messages: Belongs to the TrpC family.

1249552:PS2015 RS08345
gene id: 1249552:PS2015_RS08345
uniprot id: A0A0S2KDY2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

1249552:PS2015 RS02035
gene id: 1249552:PS2015_RS02035
uniprot id: A0A0S2K9T2
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1249552:PS2015 RS13980
gene id: 1249552:PS2015_RS13980
uniprot id: A0A0S2KGF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the high-potential iron-sulfur protein (HiPIP) family.
messages: Homodimer.
messages: Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria.

1249552:PS2015 RS06120
gene id: 1249552:PS2015_RS06120
uniprot id: A0A0S2KCH8
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS15710
gene id: 1249552:PS2015_RS15710
uniprot id: A0A0S2KE03
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

1249552:PS2015 RS15180
gene id: 1249552:PS2015_RS15180
uniprot id: A0A0S2KH49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1249552:PS2015 RS12255
gene id: 1249552:PS2015_RS12255
uniprot id: A0A0S2KFJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1249552:PS2015 RS07885
gene id: 1249552:PS2015_RS07885
uniprot id: A0A0S2KD49
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

1249552:PS2015 RS08185
gene id: 1249552:PS2015_RS08185
uniprot id: A0A0S2KE87
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

1249552:PS2015 RS03840
gene id: 1249552:PS2015_RS03840
uniprot id: A0A0S2KAW8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1249552:PS2015 RS12280
gene id: 1249552:PS2015_RS12280
uniprot id: A0A0S2KFI5
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1249552:PS2015 RS15140
gene id: 1249552:PS2015_RS15140
uniprot id: A0A0S2KHB8
names: Similarity
messages: Belongs to the thioredoxin family.

1249552:PS2015 RS10560
gene id: 1249552:PS2015_RS10560
uniprot id: A0A0S2KEL9
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

1249552:PS2015 RS07530
gene id: 1249552:PS2015_RS07530
uniprot id: A0A0S2KCX7
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1249552:PS2015 RS13785
gene id: 1249552:PS2015_RS13785
uniprot id: A0A0S2KGB6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1249552:PS2015 RS08435
gene id: 1249552:PS2015_RS08435
uniprot id: A0A0S2KDT1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1249552:PS2015 RS13465
gene id: 1249552:PS2015_RS13465
uniprot id: A0A0S2KH87
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

1249552:PS2015 RS14150
gene id: 1249552:PS2015_RS14150
uniprot id: A0A0S2KGH4
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1249552:PS2015 RS01380
gene id: 1249552:PS2015_RS01380
uniprot id: A0A0S2K9H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1249552:PS2015 RS15050
gene id: 1249552:PS2015_RS15050
uniprot id: A0A0S2KH20
names: Similarity
messages: Belongs to the UPF0225 family.

1249552:PS2015 RS04715
gene id: 1249552:PS2015_RS04715
uniprot id: A0A0S2KCG2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

1249552:PS2015 RS07705
gene id: 1249552:PS2015_RS07705
uniprot id: A0A0S2KD88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm

1249552:PS2015 RS03445
gene id: 1249552:PS2015_RS03445
uniprot id: A0A0S2KAJ0
names: Similarity
messages: Belongs to the bacterial secretin family.

1249552:PS2015 RS12585
gene id: 1249552:PS2015_RS12585
uniprot id: A0A0S2KGH7
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

1249552:PS2015 RS09090
gene id: 1249552:PS2015_RS09090
uniprot id: A0A0S2KEK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1249552:PS2015 RS04890
gene id: 1249552:PS2015_RS04890
uniprot id: A0A0S2KBF4
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS01960
gene id: 1249552:PS2015_RS01960
uniprot id: A0A0S2K9R3
names: Similarity
messages: Belongs to the GSP E family.

1249552:PS2015 RS07410
gene id: 1249552:PS2015_RS07410
uniprot id: A0A0S2KCW2
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

1249552:PS2015 RS08420
gene id: 1249552:PS2015_RS08420
uniprot id: A0A0S2KED5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

1249552:PS2015 RS05675
gene id: 1249552:PS2015_RS05675
uniprot id: A0A0S2KBV6
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS13300
gene id: 1249552:PS2015_RS13300
uniprot id: A0A0S2KGN6
names: Similarity
messages: Belongs to the YjdM family.

1249552:PS2015 RS14240
gene id: 1249552:PS2015_RS14240
uniprot id: A0A0S2KGU1
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1249552:PS2015 RS03215
gene id: 1249552:PS2015_RS03215
uniprot id: A0A0S2KB64
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

1249552:PS2015 RS07920
gene id: 1249552:PS2015_RS07920
uniprot id: A0A0S2KD56
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1249552:PS2015 RS07240
gene id: 1249552:PS2015_RS07240
uniprot id: A0A0S2KCT1
names: Similarity
messages: Belongs to the peptidase S49 family.

1249552:PS2015 RS06880
gene id: 1249552:PS2015_RS06880
uniprot id: A0A0S2KCJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1249552:PS2015 RS05825
gene id: 1249552:PS2015_RS05825
uniprot id: A0A0S2KC85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1249552:PS2015 RS07430
gene id: 1249552:PS2015_RS07430
uniprot id: A0A0S2KDJ4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1249552:PS2015 RS07950
gene id: 1249552:PS2015_RS07950
uniprot id: A0A0S2KD50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1249552:PS2015 RS12590
gene id: 1249552:PS2015_RS12590
uniprot id: A0A0S2KG28
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

1249552:PS2015 RS06180
gene id: 1249552:PS2015_RS06180
uniprot id: A0A0S2KC54
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1249552:PS2015 RS07190
gene id: 1249552:PS2015_RS07190
uniprot id: A0A0S2KCQ9
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS12370
gene id: 1249552:PS2015_RS12370
uniprot id: A0A0S2KG40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1249552:PS2015 RS08585
gene id: 1249552:PS2015_RS08585
uniprot id: A0A0S2KEG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aromatic amine dehydrogenase heavy chain family.
messages: Periplasm

1249552:PS2015 RS10015
gene id: 1249552:PS2015_RS10015
uniprot id: A0A0S2KFA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1249552:PS2015 RS03835
gene id: 1249552:PS2015_RS03835
uniprot id: A0A0S2KAV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

1249552:PS2015 RS09430
gene id: 1249552:PS2015_RS09430
uniprot id: A0A0S2KEK7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1249552:PS2015 RS12555
gene id: 1249552:PS2015_RS12555
uniprot id: A0A0S2KGA2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

1249552:PS2015 RS12840
gene id: 1249552:PS2015_RS12840
uniprot id: A0A0S2KFV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1249552:PS2015 RS07995
gene id: 1249552:PS2015_RS07995
uniprot id: A0A0S2KD70
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

1249552:PS2015 RS06150
gene id: 1249552:PS2015_RS06150
uniprot id: A0A0S2KC70
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS15290
gene id: 1249552:PS2015_RS15290
uniprot id: A0A0S2KH66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1249552:PS2015 RS00205
gene id: 1249552:PS2015_RS00205
uniprot id: A0A0S2K9L2
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

1249552:PS2015 RS07390
gene id: 1249552:PS2015_RS07390
uniprot id: A0A0S2KCV4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

1249552:PS2015 RS04960
gene id: 1249552:PS2015_RS04960
uniprot id: A0A0S2KC68
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1249552:PS2015 RS08590
gene id: 1249552:PS2015_RS08590
uniprot id: A0A0S2KE28
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

1249552:PS2015 RS07005
gene id: 1249552:PS2015_RS07005
uniprot id: A0A0S2KCP5
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1249552:PS2015 RS10470
gene id: 1249552:PS2015_RS10470
uniprot id: A0A0S2KEI1
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1249552:PS2015 RS10435
gene id: 1249552:PS2015_RS10435
uniprot id: A0A0S2KFA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1249552:PS2015 RS03820
gene id: 1249552:PS2015_RS03820
uniprot id: A0A0S2KBA4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1249552:PS2015 RS12595
gene id: 1249552:PS2015_RS12595
uniprot id: A0A0S2KFN7
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS03060
gene id: 1249552:PS2015_RS03060
uniprot id: A0A0S2KAF6
names: Similarity
messages: Belongs to the peptidase U62 family.

1249552:PS2015 RS07630
gene id: 1249552:PS2015_RS07630
uniprot id: A0A0S2KD03
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1249552:PS2015 RS08430
gene id: 1249552:PS2015_RS08430
uniprot id: A0A0S2KE38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

1249552:PS2015 RS06890
gene id: 1249552:PS2015_RS06890
uniprot id: A0A0S2KCK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1249552:PS2015 RS11365
gene id: 1249552:PS2015_RS11365
uniprot id: A0A0S2KEY9
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS10120
gene id: 1249552:PS2015_RS10120
uniprot id: A0A0S2KEA3
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

1249552:PS2015 RS09955
gene id: 1249552:PS2015_RS09955
uniprot id: A0A0S2KE76
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1249552:PS2015 RS07500
gene id: 1249552:PS2015_RS07500
uniprot id: A0A0S2KDV8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1249552:PS2015 RS06705
gene id: 1249552:PS2015_RS06705
uniprot id: A0A0S2KCU9
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

1249552:PS2015 RS14370
gene id: 1249552:PS2015_RS14370
uniprot id: A0A0S2KGP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1249552:PS2015 RS14100
gene id: 1249552:PS2015_RS14100
uniprot id: A0A0S2KGK0
names: Subunit
messages: Monomer. Interacts with PqqE.

1249552:PS2015 RS02195
gene id: 1249552:PS2015_RS02195
uniprot id: A0A0S2K9W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1249552:PS2015 RS01635
gene id: 1249552:PS2015_RS01635
uniprot id: A0A0S2KAA7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1249552:PS2015 RS06585
gene id: 1249552:PS2015_RS06585
uniprot id: A0A0S2KCZ6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

1249552:PS2015 RS07945
gene id: 1249552:PS2015_RS07945
uniprot id: A0A0S2KD52
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1249552:PS2015 RS01440
gene id: 1249552:PS2015_RS01440
uniprot id: A0A0S2K9S6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1249552:PS2015 RS02650
gene id: 1249552:PS2015_RS02650
uniprot id: A0A0S2KAQ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

1249552:PS2015 RS14885
gene id: 1249552:PS2015_RS14885
uniprot id: A0A0S2KH13
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1249552:PS2015 RS12285
gene id: 1249552:PS2015_RS12285
uniprot id: A0A0S2KG53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1249552:PS2015 RS03225
gene id: 1249552:PS2015_RS03225
uniprot id: A0A0S2KAI2
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1249552:PS2015 RS10515
gene id: 1249552:PS2015_RS10515
uniprot id: A0A0S2KFC4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1249552:PS2015 RS09920
gene id: 1249552:PS2015_RS09920
uniprot id: A0A0S2KF77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1249552:PS2015 RS05975
gene id: 1249552:PS2015_RS05975
uniprot id: A0A0S2KC18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1249552:PS2015 RS12535
gene id: 1249552:PS2015_RS12535
uniprot id: A0A0S2KFS4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1249552:PS2015 RS05810
gene id: 1249552:PS2015_RS05810
uniprot id: A0A0S2KBX3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1249552:PS2015 RS04950
gene id: 1249552:PS2015_RS04950
uniprot id: A0A0S2KCK0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1249552:PS2015 RS01430
gene id: 1249552:PS2015_RS01430
uniprot id: A0A0S2K9G8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1249552:PS2015 RS11485
gene id: 1249552:PS2015_RS11485
uniprot id: A0A0S2KFP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1249552:PS2015 RS00035
gene id: 1249552:PS2015_RS00035
uniprot id: A0A0S2K8N9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1249552:PS2015 RS04190
gene id: 1249552:PS2015_RS04190
uniprot id: A0A0S2KB06
names: Similarity
messages: Belongs to the MipA/OmpV family.

1249552:PS2015 RS13360
gene id: 1249552:PS2015_RS13360
uniprot id: A0A0S2KG57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1249552:PS2015 RS14825
gene id: 1249552:PS2015_RS14825
uniprot id: A0A0S2KGW5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1249552:PS2015 RS12175
gene id: 1249552:PS2015_RS12175
uniprot id: A0A0S2KFI1
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1249552:PS2015 RS07325
gene id: 1249552:PS2015_RS07325
uniprot id: A0A0S2KCU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1249552:PS2015 RS09065
gene id: 1249552:PS2015_RS09065
uniprot id: A0A0S2KES3
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1249552:PS2015 RS00235
gene id: 1249552:PS2015_RS00235
uniprot id: A0A0S2K928
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1249552:PS2015 RS03335
gene id: 1249552:PS2015_RS03335
uniprot id: A0A0S2KAX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

1249552:PS2015 RS06440
gene id: 1249552:PS2015_RS06440
uniprot id: A0A0S2KDB3
names: Similarity
messages: Belongs to the RutC family.

1249552:PS2015 RS02225
gene id: 1249552:PS2015_RS02225
uniprot id: A0A0S2K9Y3
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

1249552:PS2015 RS14840
gene id: 1249552:PS2015_RS14840
uniprot id: A0A0S2KHZ1
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

1249552:PS2015 RS11465
gene id: 1249552:PS2015_RS11465
uniprot id: A0A0S2KF59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1249552:PS2015 RS03745
gene id: 1249552:PS2015_RS03745
uniprot id: A0A0S2KAT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1249552:PS2015 RS10595
gene id: 1249552:PS2015_RS10595
uniprot id: A0A0S2KF72
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1249552:PS2015 RS12600
gene id: 1249552:PS2015_RS12600
uniprot id: A0A0S2KFM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1249552:PS2015 RS06790
gene id: 1249552:PS2015_RS06790
uniprot id: A0A0S2KCH2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA-dependent ATPase and 5'-3' DNA helicase.

1249552:PS2015 RS00400
gene id: 1249552:PS2015_RS00400
uniprot id: A0A0S2K8Z1
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1249552:PS2015 RS00560
gene id: 1249552:PS2015_RS00560
uniprot id: A0A0S2K969
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

1249552:PS2015 RS13915
gene id: 1249552:PS2015_RS13915
uniprot id: A0A0S2KGM2
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

1249552:PS2015 RS00465
gene id: 1249552:PS2015_RS00465
uniprot id: A0A0S2K8X6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

1249552:PS2015 RS00300
gene id: 1249552:PS2015_RS00300
uniprot id: A0A0S2K8T2
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1249552:PS2015 RS02145
gene id: 1249552:PS2015_RS02145
uniprot id: A0A0S2KAW2
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

1249552:PS2015 RS05845
gene id: 1249552:PS2015_RS05845
uniprot id: A0A0S2KC20
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Homodimer.

1249552:PS2015 RS13900
gene id: 1249552:PS2015_RS13900
uniprot id: A0A0S2KGE6
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

1249552:PS2015 RS09115
gene id: 1249552:PS2015_RS09115
uniprot id: A0A0S2KDV3
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1249552:PS2015 RS09460
gene id: 1249552:PS2015_RS09460
uniprot id: A0A0S2KE80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1249552:PS2015 RS11615
gene id: 1249552:PS2015_RS11615
uniprot id: A0A0S2KF63
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1249552:PS2015 RS13575
gene id: 1249552:PS2015_RS13575
uniprot id: A0A0S2KGA1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1249552:PS2015 RS11640
gene id: 1249552:PS2015_RS11640
uniprot id: A0A0S2KF71
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1249552:PS2015 RS09230
gene id: 1249552:PS2015_RS09230
uniprot id: A0A0S2KDV9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1249552:PS2015 RS02395
gene id: 1249552:PS2015_RS02395
uniprot id: A0A0S2KAQ9
names: Similarity
messages: Belongs to the peptidase S1C family.

1249552:PS2015 RS09305
gene id: 1249552:PS2015_RS09305
uniprot id: A0A0S2KEX1
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1249552:PS2015 RS14780
gene id: 1249552:PS2015_RS14780
uniprot id: A0A0S2KI09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1249552:PS2015 RS01930
gene id: 1249552:PS2015_RS01930
uniprot id: A0A0S2K9T4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

1249552:PS2015 RS05735
gene id: 1249552:PS2015_RS05735
uniprot id: A0A0S2KBX6
names: Similarity
messages: Belongs to the SCO1/2 family.

1249552:PS2015 RS11495
gene id: 1249552:PS2015_RS11495
uniprot id: A0A0S2KF26
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1249552:PS2015 RS03825
gene id: 1249552:PS2015_RS03825
uniprot id: A0A0S2KAT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1249552:PS2015 RS12935
gene id: 1249552:PS2015_RS12935
uniprot id: A0A0S2KFW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1249552:PS2015 RS14925
gene id: 1249552:PS2015_RS14925
uniprot id: A0A0S2KGY0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1249552:PS2015 RS00720
gene id: 1249552:PS2015_RS00720
uniprot id: A0A0S2K9B1
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

1249552:PS2015 RS13270
gene id: 1249552:PS2015_RS13270
uniprot id: A0A0S2KG42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1249552:PS2015 RS08640
gene id: 1249552:PS2015_RS08640
uniprot id: A0A0S2KDK2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1249552:PS2015 RS12310
gene id: 1249552:PS2015_RS12310
uniprot id: A0A0S2KG40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1249552:PS2015 RS06220
gene id: 1249552:PS2015_RS06220
uniprot id: A0A0S2KCE0
names: Similarity
messages: Belongs to the aspartokinase family.

1249552:PS2015 RS09525
gene id: 1249552:PS2015_RS09525
uniprot id: A0A0S2KEF4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1249552:PS2015 RS13370
gene id: 1249552:PS2015_RS13370
uniprot id: A0A0S2KH45
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1249552:PS2015 RS08280
gene id: 1249552:PS2015_RS08280
uniprot id: A0A0S2KDB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

1249552:PS2015 RS06285
gene id: 1249552:PS2015_RS06285
uniprot id: A0A0S2KCL9
names: Similarity
messages: Belongs to the HesB/IscA family.

1249552:PS2015 RS15270
gene id: 1249552:PS2015_RS15270
uniprot id: A0A0S2KI87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1249552:PS2015 RS00145
gene id: 1249552:PS2015_RS00145
uniprot id: A0A0S2K8P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1249552:PS2015 RS00070
gene id: 1249552:PS2015_RS00070
uniprot id: A0A0S2K8Y2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1249552:PS2015 RS14105
gene id: 1249552:PS2015_RS14105
uniprot id: A0A0S2KH43
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.

1249552:PS2015 RS05300
gene id: 1249552:PS2015_RS05300
uniprot id: A0A0S2KCB4
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

1249552:PS2015 RS13695
gene id: 1249552:PS2015_RS13695
uniprot id: A0A0S2KGW4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1249552:PS2015 RS10210
gene id: 1249552:PS2015_RS10210
uniprot id: A0A0S2KEB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

1249552:PS2015 RS07930
gene id: 1249552:PS2015_RS07930
uniprot id: A0A0S2KDQ7
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1249552:PS2015 RS12240
gene id: 1249552:PS2015_RS12240
uniprot id: A0A0S2KFW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1249552:PS2015 RS04375
gene id: 1249552:PS2015_RS04375
uniprot id: A0A0S2KB62
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

1249552:PS2015 RS03950
gene id: 1249552:PS2015_RS03950
uniprot id: A0A0S2KBI4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1249552:PS2015 RS12345
gene id: 1249552:PS2015_RS12345
uniprot id: A0A0S2KFP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1249552:PS2015 RS13725
gene id: 1249552:PS2015_RS13725
uniprot id: A0A0S2KH52
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

1249552:PS2015 RS10395
gene id: 1249552:PS2015_RS10395
uniprot id: A0A0S2KEG6
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1249552:PS2015 RS02430
gene id: 1249552:PS2015_RS02430
uniprot id: A0A0S2KA48
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

1249552:PS2015 RS02535
gene id: 1249552:PS2015_RS02535
uniprot id: A0A0S2KB37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1249552:PS2015 RS09375
gene id: 1249552:PS2015_RS09375
uniprot id: A0A0S2KDX8
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1249552:PS2015 RS10660
gene id: 1249552:PS2015_RS10660
uniprot id: A0A0S2KEJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1249552:PS2015 RS15300
gene id: 1249552:PS2015_RS15300
uniprot id: A0A0S2KH98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1249552:PS2015 RS10880
gene id: 1249552:PS2015_RS10880
uniprot id: A0A0S2KEN6
names: Similarity
messages: Belongs to the UPF0250 family.

1249552:PS2015 RS04605
gene id: 1249552:PS2015_RS04605
uniprot id: A0A0S2KB84
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1249552:PS2015 RS12480
gene id: 1249552:PS2015_RS12480
uniprot id: A0A0S2KGM4
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS07140
gene id: 1249552:PS2015_RS07140
uniprot id: A0A0S2KCR0
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1249552:PS2015 RS06510
gene id: 1249552:PS2015_RS06510
uniprot id: A0A0S2KCB7
names: Similarity
messages: Belongs to the citrate synthase family.

1249552:PS2015 RS11415
gene id: 1249552:PS2015_RS11415
uniprot id: A0A0S2KF09
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1249552:PS2015 RS06615
gene id: 1249552:PS2015_RS06615
uniprot id: A0A0S2KD18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1249552:PS2015 RS00425
gene id: 1249552:PS2015_RS00425
uniprot id: A0A0S2K9J7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1249552:PS2015 RS00230
gene id: 1249552:PS2015_RS00230
uniprot id: A0A0S2K912
names: Similarity
messages: Belongs to the GSP E family.

1249552:PS2015 RS07880
gene id: 1249552:PS2015_RS07880
uniprot id: A0A0S2KD34
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1249552:PS2015 RS02725
gene id: 1249552:PS2015_RS02725
uniprot id: A0A0S2KBA9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1249552:PS2015 RS10675
gene id: 1249552:PS2015_RS10675
uniprot id: A0A0S2KFL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1249552:PS2015 RS05980
gene id: 1249552:PS2015_RS05980
uniprot id: A0A0S2KCB2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1249552:PS2015 RS01760
gene id: 1249552:PS2015_RS01760
uniprot id: A0A0S2K9P8
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1249552:PS2015 RS02715
gene id: 1249552:PS2015_RS02715
uniprot id: A0A0S2KA35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1249552:PS2015 RS01980
gene id: 1249552:PS2015_RS01980
uniprot id: A0A0S2K9R4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1249552:PS2015 RS01515
gene id: 1249552:PS2015_RS01515
uniprot id: A0A0S2K9I2
names: Similarity
messages: Belongs to the NodU/CmcH family.

1249552:PS2015 RS02845
gene id: 1249552:PS2015_RS02845
uniprot id: A0A0S2KAE9
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

1249552:PS2015 RS15065
gene id: 1249552:PS2015_RS15065
uniprot id: A0A0S2KH70
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

1249552:PS2015 RS02790
gene id: 1249552:PS2015_RS02790
uniprot id: A0A0S2KB78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1249552:PS2015 RS15295
gene id: 1249552:PS2015_RS15295
uniprot id: A0A0S2KH51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1249552:PS2015 RS12000
gene id: 1249552:PS2015_RS12000
uniprot id: A0A0S2KFS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

1249552:PS2015 RS06900
gene id: 1249552:PS2015_RS06900
uniprot id: A0A0S2KCM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1249552:PS2015 RS11685
gene id: 1249552:PS2015_RS11685
uniprot id: A0A0S2KF46
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1249552:PS2015 RS12875
gene id: 1249552:PS2015_RS12875
uniprot id: A0A0S2KGG0
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1249552:PS2015 RS01550
gene id: 1249552:PS2015_RS01550
uniprot id: A0A0S2KA91
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

1249552:PS2015 RS04420
gene id: 1249552:PS2015_RS04420
uniprot id: A0A0S2KB85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

1249552:PS2015 RS05795
gene id: 1249552:PS2015_RS05795
uniprot id: A0A0S2KCH7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1249552:PS2015 RS11665
gene id: 1249552:PS2015_RS11665
uniprot id: A0A0S2KG76
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1249552:PS2015 RS10070
gene id: 1249552:PS2015_RS10070
uniprot id: A0A0S2KEB4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of five rings (E,L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1249552:PS2015 RS04415
gene id: 1249552:PS2015_RS04415
uniprot id: A0A0S2KB47
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1249552:PS2015 RS14065
gene id: 1249552:PS2015_RS14065
uniprot id: A0A0S2KGG5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1249552:PS2015 RS04770
gene id: 1249552:PS2015_RS04770
uniprot id: A0A0S2KBD4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1249552:PS2015 RS13045
gene id: 1249552:PS2015_RS13045
uniprot id: A0A0S2KFX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1249552:PS2015 RS02490
gene id: 1249552:PS2015_RS02490
uniprot id: A0A0S2KA30
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

1249552:PS2015 RS02525
gene id: 1249552:PS2015_RS02525
uniprot id: A0A0S2KA14
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1249552:PS2015 RS08030
gene id: 1249552:PS2015_RS08030
uniprot id: A0A0S2KD67
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1249552:PS2015 RS07490
gene id: 1249552:PS2015_RS07490
uniprot id: A0A0S2KCX2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1249552:PS2015 RS03325
gene id: 1249552:PS2015_RS03325
uniprot id: A0A0S2KAK3
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS12305
gene id: 1249552:PS2015_RS12305
uniprot id: A0A0S2KGL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1249552:PS2015 RS06100
gene id: 1249552:PS2015_RS06100
uniprot id: A0A0S2KC40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

1249552:PS2015 RS09535
gene id: 1249552:PS2015_RS09535
uniprot id: A0A0S2KE06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

1249552:PS2015 RS00410
gene id: 1249552:PS2015_RS00410
uniprot id: A0A0S2K8W5
names: Similarity
messages: Belongs to the P(II) protein family.

1249552:PS2015 RS01465
gene id: 1249552:PS2015_RS01465
uniprot id: A0A0S2KA70
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS13265
gene id: 1249552:PS2015_RS13265
uniprot id: A0A0S2KG12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1249552:PS2015 RS04170
gene id: 1249552:PS2015_RS04170
uniprot id: A0A0S2KB39
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1249552:PS2015 RS04150
gene id: 1249552:PS2015_RS04150
uniprot id: A0A0S2KBN0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

1249552:PS2015 RS00625
gene id: 1249552:PS2015_RS00625
uniprot id: A0A0S2K908
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1249552:PS2015 RS07830
gene id: 1249552:PS2015_RS07830
uniprot id: A0A0S2KD33
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1249552:PS2015 RS11180
gene id: 1249552:PS2015_RS11180
uniprot id: A0A0S2KFX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1249552:PS2015 RS15200
gene id: 1249552:PS2015_RS15200
uniprot id: A0A0S2KHH9
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1249552:PS2015 RS02475
gene id: 1249552:PS2015_RS02475
uniprot id: A0A0S2KAS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1249552:PS2015 RS09385
gene id: 1249552:PS2015_RS09385
uniprot id: A0A0S2KEI3
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 104 family.
messages: Protein-arginine rhamnosyltransferase that catalyzes the transfer of a single rhamnose to elongation factor P (EF-P) on 'Lys-32', a modification required for EF-P-dependent rescue of polyproline stalled ribosomes.

1249552:PS2015 RS08835
gene id: 1249552:PS2015_RS08835
uniprot id: A0A0S2KED6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

1249552:PS2015 RS12190
gene id: 1249552:PS2015_RS12190
uniprot id: A0A0S2KFG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1249552:PS2015 RS03780
gene id: 1249552:PS2015_RS03780
uniprot id: A0A0S2KAR7
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1249552:PS2015 RS06015
gene id: 1249552:PS2015_RS06015
uniprot id: A0A0S2KC45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1249552:PS2015 RS00760
gene id: 1249552:PS2015_RS00760
uniprot id: A0A0S2K941
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1249552:PS2015 RS01600
gene id: 1249552:PS2015_RS01600
uniprot id: A0A0S2K9I8
names: Cofactor
names: Similarity
messages: Belongs to the WrbA family.
messages: Binds 1 FMN per monomer.

1249552:PS2015 RS00180
gene id: 1249552:PS2015_RS00180
uniprot id: A0A0S2K9F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1249552:PS2015 RS02875
gene id: 1249552:PS2015_RS02875
uniprot id: A0A0S2KA64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

1249552:PS2015 RS13290
gene id: 1249552:PS2015_RS13290
uniprot id: A0A0S2KG39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1249552:PS2015 RS13165
gene id: 1249552:PS2015_RS13165
uniprot id: A0A0S2KG21
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS09510
gene id: 1249552:PS2015_RS09510
uniprot id: A0A0S2KF27
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1249552:PS2015 RS11460
gene id: 1249552:PS2015_RS11460
uniprot id: A0A0S2KF99
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1249552:PS2015 RS09415
gene id: 1249552:PS2015_RS09415
uniprot id: A0A0S2KDZ2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1249552:PS2015 RS02350
gene id: 1249552:PS2015_RS02350
uniprot id: A0A0S2KA33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1249552:PS2015 RS00675
gene id: 1249552:PS2015_RS00675
uniprot id: A0A0S2KA39
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.

1249552:PS2015 RS10975
gene id: 1249552:PS2015_RS10975
uniprot id: A0A0S2KF13
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1249552:PS2015 RS03910
gene id: 1249552:PS2015_RS03910
uniprot id: A0A0S2KAV4
names: Similarity
messages: Belongs to the thioesterase PaaI family.

1249552:PS2015 RS07720
gene id: 1249552:PS2015_RS07720
uniprot id: A0A0S2KD14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

1249552:PS2015 RS06060
gene id: 1249552:PS2015_RS06060
uniprot id: A0A0S2KCC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1249552:PS2015 RS10450
gene id: 1249552:PS2015_RS10450
uniprot id: A0A0S2KEF8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1249552:PS2015 RS12360
gene id: 1249552:PS2015_RS12360
uniprot id: A0A0S2KFK3
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1249552:PS2015 RS09235
gene id: 1249552:PS2015_RS09235
uniprot id: A0A0S2KDW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1249552:PS2015 RS07215
gene id: 1249552:PS2015_RS07215
uniprot id: A0A0S2KCS4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

1249552:PS2015 RS00735
gene id: 1249552:PS2015_RS00735
uniprot id: A0A0S2K939
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1249552:PS2015 RS04245
gene id: 1249552:PS2015_RS04245
uniprot id: A0A0S2KB13
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS12005
gene id: 1249552:PS2015_RS12005
uniprot id: A0A0S2KFB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

1249552:PS2015 RS13175
gene id: 1249552:PS2015_RS13175
uniprot id: A0A0S2KG56
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1249552:PS2015 RS02130
gene id: 1249552:PS2015_RS02130
uniprot id: A0A0S2KAV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

1249552:PS2015 RS10350
gene id: 1249552:PS2015_RS10350
uniprot id: A0A0S2KFH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

1249552:PS2015 RS09140
gene id: 1249552:PS2015_RS09140
uniprot id: A0A0S2KEU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1249552:PS2015 RS10045
gene id: 1249552:PS2015_RS10045
uniprot id: A0A0S2KEB5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

1249552:PS2015 RS12165
gene id: 1249552:PS2015_RS12165
uniprot id: A0A0S2KFF2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1249552:PS2015 RS01695
gene id: 1249552:PS2015_RS01695
uniprot id: A0A0S2K9S2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1249552:PS2015 RS09225
gene id: 1249552:PS2015_RS09225
uniprot id: A0A0S2KEW4
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1249552:PS2015 RS09925
gene id: 1249552:PS2015_RS09925
uniprot id: A0A0S2KE90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1249552:PS2015 RS14495
gene id: 1249552:PS2015_RS14495
uniprot id: A0A0S2KGV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
messages: Monomer.

1249552:PS2015 RS05420
gene id: 1249552:PS2015_RS05420
uniprot id: A0A0S2KBP9
names: Similarity
messages: Belongs to the peptidase S66 family.

1249552:PS2015 RS08530
gene id: 1249552:PS2015_RS08530
uniprot id: A0A0S2KDH7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

1249552:PS2015 RS13805
gene id: 1249552:PS2015_RS13805
uniprot id: A0A0S2KH71
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1249552:PS2015 RS07900
gene id: 1249552:PS2015_RS07900
uniprot id: A0A0S2KDP0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

1249552:PS2015 RS12995
gene id: 1249552:PS2015_RS12995
uniprot id: A0A0S2KFX1
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

1249552:PS2015 RS11035
gene id: 1249552:PS2015_RS11035
uniprot id: A0A0S2KF85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1249552:PS2015 RS06760
gene id: 1249552:PS2015_RS06760
uniprot id: A0A0S2KCF2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1249552:PS2015 RS05440
gene id: 1249552:PS2015_RS05440
uniprot id: A0A0S2KCP8
names: Similarity
messages: Belongs to the Gfa family.

1249552:PS2015 RS08140
gene id: 1249552:PS2015_RS08140
uniprot id: A0A0S2KDG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1249552:PS2015 RS11150
gene id: 1249552:PS2015_RS11150
uniprot id: A0A0S2KEU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

1249552:PS2015 RS09390
gene id: 1249552:PS2015_RS09390
uniprot id: A0A0S2KEZ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1249552:PS2015 RS06865
gene id: 1249552:PS2015_RS06865
uniprot id: A0A0S2KCY1
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1249552:PS2015 RS07780
gene id: 1249552:PS2015_RS07780
uniprot id: A0A0S2KD21
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1249552:PS2015 RS13815
gene id: 1249552:PS2015_RS13815
uniprot id: A0A0S2KGD0
names: Cofactor
messages: Can also use Mn(2+) ion.

1249552:PS2015 RS09575
gene id: 1249552:PS2015_RS09575
uniprot id: A0A0S2KF25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1249552:PS2015 RS09135
gene id: 1249552:PS2015_RS09135
uniprot id: A0A0S2KED9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

1249552:PS2015 RS08525
gene id: 1249552:PS2015_RS08525
uniprot id: A0A0S2KDG8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

1249552:PS2015 RS12210
gene id: 1249552:PS2015_RS12210
uniprot id: A0A0S2KGI1
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1249552:PS2015 RS03265
gene id: 1249552:PS2015_RS03265
uniprot id: A0A0S2KAF3
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS12185
gene id: 1249552:PS2015_RS12185
uniprot id: A0A0S2KFL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1249552:PS2015 RS14935
gene id: 1249552:PS2015_RS14935
uniprot id: A0A0S2KI33
names: Similarity
messages: Belongs to the UPF0758 family.

1249552:PS2015 RS01680
gene id: 1249552:PS2015_RS01680
uniprot id: A0A0S2K9K6
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS02925
gene id: 1249552:PS2015_RS02925
uniprot id: A0A0S2KAG5
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1249552:PS2015 RS11660
gene id: 1249552:PS2015_RS11660
uniprot id: A0A0S2KF75
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1249552:PS2015 RS12290
gene id: 1249552:PS2015_RS12290
uniprot id: A0A0S2KGJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1249552:PS2015 RS04610
gene id: 1249552:PS2015_RS04610
uniprot id: A0A0S2KBA1
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS08685
gene id: 1249552:PS2015_RS08685
uniprot id: A0A0S2KDJ5
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1249552:PS2015 RS03945
gene id: 1249552:PS2015_RS03945
uniprot id: A0A0S2KAV8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1249552:PS2015 RS12250
gene id: 1249552:PS2015_RS12250
uniprot id: A0A0S2KFF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1249552:PS2015 RS00520
gene id: 1249552:PS2015_RS00520
uniprot id: A0A0S2K8Y9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1249552:PS2015 RS09205
gene id: 1249552:PS2015_RS09205
uniprot id: A0A0S2KDU8
names: Similarity
messages: Belongs to the SUI1 family.

1249552:PS2015 RS08175
gene id: 1249552:PS2015_RS08175
uniprot id: A0A0S2KD94
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1249552:PS2015 RS13220
gene id: 1249552:PS2015_RS13220
uniprot id: A0A0S2KGM1
names: Similarity
messages: Belongs to the pirin family.

1249552:PS2015 RS13825
gene id: 1249552:PS2015_RS13825
uniprot id: A0A0S2KGF0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1249552:PS2015 RS12785
gene id: 1249552:PS2015_RS12785
uniprot id: A0A0S2KFU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

1249552:PS2015 RS02500
gene id: 1249552:PS2015_RS02500
uniprot id: A0A0S2KA79
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1249552:PS2015 RS04210
gene id: 1249552:PS2015_RS04210
uniprot id: A0A0S2KB19
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1249552:PS2015 RS11265
gene id: 1249552:PS2015_RS11265
uniprot id: A0A0S2KFI9
names: Similarity
messages: Belongs to the bacterial glucokinase family.

1249552:PS2015 RS07335
gene id: 1249552:PS2015_RS07335
uniprot id: A0A0S2KDS9
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1249552:PS2015 RS08160
gene id: 1249552:PS2015_RS08160
uniprot id: A0A0S2KD98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1249552:PS2015 RS07520
gene id: 1249552:PS2015_RS07520
uniprot id: A0A0S2KCW7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1249552:PS2015 RS15330
gene id: 1249552:PS2015_RS15330
uniprot id: A0A0S2KHU1
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

1249552:PS2015 RS01625
gene id: 1249552:PS2015_RS01625
uniprot id: A0A0S2K9K8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1249552:PS2015 RS10430
gene id: 1249552:PS2015_RS10430
uniprot id: A0A0S2KF40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1249552:PS2015 RS13025
gene id: 1249552:PS2015_RS13025
uniprot id: A0A0S2KFW4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1249552:PS2015 RS13225
gene id: 1249552:PS2015_RS13225
uniprot id: A0A0S2KGV9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1249552:PS2015 RS09155
gene id: 1249552:PS2015_RS09155
uniprot id: A0A0S2KEV9
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1249552:PS2015 RS01820
gene id: 1249552:PS2015_RS01820
uniprot id: A0A0S2KAQ7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1249552:PS2015 RS01385
gene id: 1249552:PS2015_RS01385
uniprot id: A0A0S2KA56
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1249552:PS2015 RS02175
gene id: 1249552:PS2015_RS02175
uniprot id: A0A0S2KA38
names: Similarity
messages: Belongs to the HSP15 family.

1249552:PS2015 RS08050
gene id: 1249552:PS2015_RS08050
uniprot id: A0A0S2KD84
names: Similarity
messages: Belongs to the CvfB family.

1249552:PS2015 RS00710
gene id: 1249552:PS2015_RS00710
uniprot id: A0A0S2K933
names: Subcellular Location Annotation
messages: Cytoplasm

1249552:PS2015 RS05955
gene id: 1249552:PS2015_RS05955
uniprot id: A0A0S2KCM3
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1249552:PS2015 RS03235
gene id: 1249552:PS2015_RS03235
uniprot id: A0A0S2KAL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1249552:PS2015 RS11655
gene id: 1249552:PS2015_RS11655
uniprot id: A0A0S2KF53
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1249552:PS2015 RS09075
gene id: 1249552:PS2015_RS09075
uniprot id: A0A0S2KDS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1249552:PS2015 RS12245
gene id: 1249552:PS2015_RS12245
uniprot id: A0A0S2KFG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1249552:PS2015 RS12395
gene id: 1249552:PS2015_RS12395
uniprot id: A0A0S2KFL2
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
messages: Belongs to the biotin--protein ligase family.

1249552:PS2015 RS12975
gene id: 1249552:PS2015_RS12975
uniprot id: A0A0S2KGZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1249552:PS2015 RS05095
gene id: 1249552:PS2015_RS05095
uniprot id: A0A0S2KBH9
names: Similarity
messages: Belongs to the group II decarboxylase family.

1249552:PS2015 RS06595
gene id: 1249552:PS2015_RS06595
uniprot id: A0A0S2KCD0
names: Similarity
messages: Belongs to the glutamate synthase family.

1249552:PS2015 RS05830
gene id: 1249552:PS2015_RS05830
uniprot id: A0A0S2KC14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1249552:PS2015 RS09960
gene id: 1249552:PS2015_RS09960
uniprot id: A0A0S2KE77
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1249552:PS2015 RS07080
gene id: 1249552:PS2015_RS07080
uniprot id: A0A0S2KCQ1
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1249552:PS2015 RS04480
gene id: 1249552:PS2015_RS04480
uniprot id: A0A0S2KBW4
names: Subcellular Location Annotation
messages: Membrane

1249552:PS2015 RS07850
gene id: 1249552:PS2015_RS07850
uniprot id: A0A0S2KDR6
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

1249552:PS2015 RS11200
gene id: 1249552:PS2015_RS11200
uniprot id: A0A0S2KEV6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1249552:PS2015 RS10800
gene id: 1249552:PS2015_RS10800
uniprot id: A0A0S2KEP2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1249552:PS2015 RS09995
gene id: 1249552:PS2015_RS09995
uniprot id: A0A0S2KEV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm