1222016:ELD05 RS08835
gene id: 1222016:ELD05_RS08835
uniprot id: A0A3T0D6L1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1222016:ELD05 RS10945
gene id: 1222016:ELD05_RS10945
uniprot id: A0A3T0D7K9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1222016:ELD05 RS13110
gene id: 1222016:ELD05_RS13110
uniprot id: A0A3T0D8U5
names: Similarity
messages: Belongs to the P(II) protein family.

1222016:ELD05 RS06150
gene id: 1222016:ELD05_RS06150
uniprot id: A0A3T0D592
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Membrane

1222016:ELD05 RS02620
gene id: 1222016:ELD05_RS02620
uniprot id: A0A3T0D410
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1222016:ELD05 RS07365
gene id: 1222016:ELD05_RS07365
uniprot id: A0A3T0D634
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1222016:ELD05 RS07180
gene id: 1222016:ELD05_RS07180
uniprot id: A0A3T0D5W0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1222016:ELD05 RS03015
gene id: 1222016:ELD05_RS03015
uniprot id: A0A3T0D348
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1222016:ELD05 RS10400
gene id: 1222016:ELD05_RS10400
uniprot id: A0A3T0D7D2
names: Subcellular Location Annotation
messages: Cytoplasm

1222016:ELD05 RS05825
gene id: 1222016:ELD05_RS05825
uniprot id: A0A3T0D579
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1222016:ELD05 RS05365
gene id: 1222016:ELD05_RS05365
uniprot id: A0A3T0D4Z8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1222016:ELD05 RS04800
gene id: 1222016:ELD05_RS04800
uniprot id: A0A3T0D4S6
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1222016:ELD05 RS05445
gene id: 1222016:ELD05_RS05445
uniprot id: A0A3T0D521
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1222016:ELD05 RS08465
gene id: 1222016:ELD05_RS08465
uniprot id: A0A3T0D6H0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1222016:ELD05 RS00410
gene id: 1222016:ELD05_RS00410
uniprot id: A0A3T0D379
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1222016:ELD05 RS05040
gene id: 1222016:ELD05_RS05040
uniprot id: A0A3T0D4T1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1222016:ELD05 RS05055
gene id: 1222016:ELD05_RS05055
uniprot id: A0A3T0D4X4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1222016:ELD05 RS11190
gene id: 1222016:ELD05_RS11190
uniprot id: A0A3T0D869
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1222016:ELD05 RS04675
gene id: 1222016:ELD05_RS04675
uniprot id: A0A3T0D4N8
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1222016:ELD05 RS03265
gene id: 1222016:ELD05_RS03265
uniprot id: A0A3T0D3S7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1222016:ELD05 RS08720
gene id: 1222016:ELD05_RS08720
uniprot id: A0A3T0D6M9
names: Similarity
messages: Belongs to the HupF/HypC family.

1222016:ELD05 RS08735
gene id: 1222016:ELD05_RS08735
uniprot id: A0A3T0D798
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

1222016:ELD05 RS06355
gene id: 1222016:ELD05_RS06355
uniprot id: A0A3T0D5I4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1222016:ELD05 RS04775
gene id: 1222016:ELD05_RS04775
uniprot id: A0A3T0D4Q4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1222016:ELD05 RS05345
gene id: 1222016:ELD05_RS05345
uniprot id: A0A3T0D503
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

1222016:ELD05 RS05230
gene id: 1222016:ELD05_RS05230
uniprot id: A0A3T0D4Y0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1222016:ELD05 RS08600
gene id: 1222016:ELD05_RS08600
uniprot id: A0A3T0D6J4
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

1222016:ELD05 RS02990
gene id: 1222016:ELD05_RS02990
uniprot id: A0A3T0D361
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1222016:ELD05 RS03635
gene id: 1222016:ELD05_RS03635
uniprot id: A0A3T0D3P4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1222016:ELD05 RS02285
gene id: 1222016:ELD05_RS02285
uniprot id: A0A3T0D403
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1222016:ELD05 RS13120
gene id: 1222016:ELD05_RS13120
uniprot id: A0A3T0D905
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-98 inactivates the nitrogenase reductase and regulates nitrogenase activity.

1222016:ELD05 RS11590
gene id: 1222016:ELD05_RS11590
uniprot id: A0A3T0D7S4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1222016:ELD05 RS13875
gene id: 1222016:ELD05_RS13875
uniprot id: A0A3T0D8W2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1222016:ELD05 RS03495
gene id: 1222016:ELD05_RS03495
uniprot id: A0A3T0D3F2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1222016:ELD05 RS07710
gene id: 1222016:ELD05_RS07710
uniprot id: A0A3T0D633
names: Similarity
messages: Belongs to the EamA transporter family.

1222016:ELD05 RS03470
gene id: 1222016:ELD05_RS03470
uniprot id: A0A3T0D3E5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1222016:ELD05 RS07645
gene id: 1222016:ELD05_RS07645
uniprot id: A0A3T0D642
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1222016:ELD05 RS06385
gene id: 1222016:ELD05_RS06385
uniprot id: A0A3T0D5F5
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1222016:ELD05 RS05415
gene id: 1222016:ELD05_RS05415
uniprot id: A0A3T0D507
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

1222016:ELD05 RS04795
gene id: 1222016:ELD05_RS04795
uniprot id: A0A3T0D4R3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1222016:ELD05 RS00255
gene id: 1222016:ELD05_RS00255
uniprot id: A0A3T0D225
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1222016:ELD05 RS01590
gene id: 1222016:ELD05_RS01590
uniprot id: A0A3T0D304
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

1222016:ELD05 RS04650
gene id: 1222016:ELD05_RS04650
uniprot id: A0A3T0D4Q0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1222016:ELD05 RS04100
gene id: 1222016:ELD05_RS04100
uniprot id: A0A3T0D9F2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1222016:ELD05 RS04665
gene id: 1222016:ELD05_RS04665
uniprot id: A0A3T0D4M6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1222016:ELD05 RS05905
gene id: 1222016:ELD05_RS05905
uniprot id: A0A3T0D5B5
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

1222016:ELD05 RS05060
gene id: 1222016:ELD05_RS05060
uniprot id: A0A3T0D4U2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1222016:ELD05 RS12920
gene id: 1222016:ELD05_RS12920
uniprot id: A0A3T0D938
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

1222016:ELD05 RS07430
gene id: 1222016:ELD05_RS07430
uniprot id: A0A3T0D5Y5
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1222016:ELD05 RS07265
gene id: 1222016:ELD05_RS07265
uniprot id: A0A3T0D5V5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1222016:ELD05 RS03365
gene id: 1222016:ELD05_RS03365
uniprot id: A0A3T0D3C4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1222016:ELD05 RS04745
gene id: 1222016:ELD05_RS04745
uniprot id: A0A3T0D4Q3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1222016:ELD05 RS03290
gene id: 1222016:ELD05_RS03290
uniprot id: A0A3T0D3Q4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1222016:ELD05 RS08760
gene id: 1222016:ELD05_RS08760
uniprot id: A0A3T0D6Z1
names: Subcellular Location Annotation
messages: Membrane

1222016:ELD05 RS07620
gene id: 1222016:ELD05_RS07620
uniprot id: A0A3T0D654
names: Similarity
messages: Belongs to the Fur family.

1222016:ELD05 RS10310
gene id: 1222016:ELD05_RS10310
uniprot id: A0A3T0D865
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1222016:ELD05 RS04720
gene id: 1222016:ELD05_RS04720
uniprot id: A0A3T0D4S4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1222016:ELD05 RS09155
gene id: 1222016:ELD05_RS09155
uniprot id: A0A3T0D7G9
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

1222016:ELD05 RS06170
gene id: 1222016:ELD05_RS06170
uniprot id: A0A3T0D5C8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1222016:ELD05 RS02840
gene id: 1222016:ELD05_RS02840
uniprot id: A0A3T0D422
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1222016:ELD05 RS10200
gene id: 1222016:ELD05_RS10200
uniprot id: A0A3T0D7I6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

1222016:ELD05 RS06290
gene id: 1222016:ELD05_RS06290
uniprot id: A0A3T0D5G9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1222016:ELD05 RS07205
gene id: 1222016:ELD05_RS07205
uniprot id: A0A3T0D5U5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1222016:ELD05 RS09265
gene id: 1222016:ELD05_RS09265
uniprot id: A0A3T0D6X8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1222016:ELD05 RS08370
gene id: 1222016:ELD05_RS08370
uniprot id: A0A3T0D6F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Membrane

1222016:ELD05 RS08025
gene id: 1222016:ELD05_RS08025
uniprot id: A0A3T0D690
names: Similarity
messages: Belongs to the FlgM family.

1222016:ELD05 RS04660
gene id: 1222016:ELD05_RS04660
uniprot id: A0A3T0D4L6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1222016:ELD05 RS04770
gene id: 1222016:ELD05_RS04770
uniprot id: A0A3T0D4T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1222016:ELD05 RS10525
gene id: 1222016:ELD05_RS10525
uniprot id: A0A3T0D7F3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1222016:ELD05 RS13105
gene id: 1222016:ELD05_RS13105
uniprot id: A0A3T0D8T0
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

1222016:ELD05 RS10205
gene id: 1222016:ELD05_RS10205
uniprot id: A0A3T0D7A5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1222016:ELD05 RS04655
gene id: 1222016:ELD05_RS04655
uniprot id: A0A3T0D4M3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1222016:ELD05 RS06860
gene id: 1222016:ELD05_RS06860
uniprot id: A0A3T0D5R4
names: Function
names: Similarity
names: Subunit
messages: Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization.
messages: Belongs to the HutP family.
messages: Homohexamer.

1222016:ELD05 RS04900
gene id: 1222016:ELD05_RS04900
uniprot id: A0A3T0D4R1
names: Subcellular Location Annotation
messages: Membrane

1222016:ELD05 RS03550
gene id: 1222016:ELD05_RS03550
uniprot id: A0A3T0D478
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

1222016:ELD05 RS00500
gene id: 1222016:ELD05_RS00500
uniprot id: A0A3T0D220
names: Similarity
messages: Belongs to the RutC family.

1222016:ELD05 RS06360
gene id: 1222016:ELD05_RS06360
uniprot id: A0A3T0D5D8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1222016:ELD05 RS12750
gene id: 1222016:ELD05_RS12750
uniprot id: A0A3T0D8D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1222016:ELD05 RS05005
gene id: 1222016:ELD05_RS05005
uniprot id: A0A3T0D4S5
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1222016:ELD05 RS08585
gene id: 1222016:ELD05_RS08585
uniprot id: A0A3T0D6W6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1222016:ELD05 RS06740
gene id: 1222016:ELD05_RS06740
uniprot id: A0A3T0D5L0
names: Subcellular Location Annotation
messages: Cytoplasm

1222016:ELD05 RS05425
gene id: 1222016:ELD05_RS05425
uniprot id: A0A3T0D504
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1222016:ELD05 RS06795
gene id: 1222016:ELD05_RS06795
uniprot id: A0A3T0D5L2
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1222016:ELD05 RS07690
gene id: 1222016:ELD05_RS07690
uniprot id: A0A3T0D689
names: Similarity
messages: Belongs to the thioredoxin family.

1222016:ELD05 RS06295
gene id: 1222016:ELD05_RS06295
uniprot id: A0A3T0D5G7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1222016:ELD05 RS06300
gene id: 1222016:ELD05_RS06300
uniprot id: A0A3T0D5C7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1222016:ELD05 RS02430
gene id: 1222016:ELD05_RS02430
uniprot id: A0A3T0D2W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1222016:ELD05 RS08755
gene id: 1222016:ELD05_RS08755
uniprot id: A0A3T0D6L5
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

1222016:ELD05 RS03520
gene id: 1222016:ELD05_RS03520
uniprot id: A0A3T0D3F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1222016:ELD05 RS12515
gene id: 1222016:ELD05_RS12515
uniprot id: A0A3T0D999
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1222016:ELD05 RS02855
gene id: 1222016:ELD05_RS02855
uniprot id: A0A3T0D3C3
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

1222016:ELD05 RS04715
gene id: 1222016:ELD05_RS04715
uniprot id: A0A3T0D4N7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1222016:ELD05 RS13115
gene id: 1222016:ELD05_RS13115
uniprot id: A0A3T0D8J0
names: Similarity
messages: Belongs to the P(II) protein family.

1222016:ELD05 RS07570
gene id: 1222016:ELD05_RS07570
uniprot id: A0A3T0D617
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1222016:ELD05 RS05970
gene id: 1222016:ELD05_RS05970
uniprot id: A0A3T0D586
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1222016:ELD05 RS06390
gene id: 1222016:ELD05_RS06390
uniprot id: A0A3T0D5F6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1222016:ELD05 RS13835
gene id: 1222016:ELD05_RS13835
uniprot id: A0A3T0D8V1
names: Similarity
messages: Belongs to the ParB family.

1222016:ELD05 RS01135
gene id: 1222016:ELD05_RS01135
uniprot id: A0A3T0D2H5
names: Similarity
messages: Belongs to the UPF0251 family.

1222016:ELD05 RS02975
gene id: 1222016:ELD05_RS02975
uniprot id: A0A3T0D3Q3
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1222016:ELD05 RS08815
gene id: 1222016:ELD05_RS08815
uniprot id: A0A3T0D706
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1222016:ELD05 RS11555
gene id: 1222016:ELD05_RS11555
uniprot id: A0A3T0D841
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1222016:ELD05 RS09715
gene id: 1222016:ELD05_RS09715
uniprot id: A0A3T0D7G2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1222016:ELD05 RS12780
gene id: 1222016:ELD05_RS12780
uniprot id: A0A3T0D8D0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1222016:ELD05 RS05870
gene id: 1222016:ELD05_RS05870
uniprot id: A0A3T0D548
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1222016:ELD05 RS07605
gene id: 1222016:ELD05_RS07605
uniprot id: A0A3T0D615
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1222016:ELD05 RS04755
gene id: 1222016:ELD05_RS04755
uniprot id: A0A3T0D4P5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

1222016:ELD05 RS05280
gene id: 1222016:ELD05_RS05280
uniprot id: A0A3T0D584
names: Similarity
messages: Belongs to the intimin/invasin family.

1222016:ELD05 RS07135
gene id: 1222016:ELD05_RS07135
uniprot id: A0A3T0D5T9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1222016:ELD05 RS10080
gene id: 1222016:ELD05_RS10080
uniprot id: A0A3T0D7C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1222016:ELD05 RS03690
gene id: 1222016:ELD05_RS03690
uniprot id: A0A3T0D3Q0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1222016:ELD05 RS04780
gene id: 1222016:ELD05_RS04780
uniprot id: A0A3T0D4P9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1222016:ELD05 RS09220
gene id: 1222016:ELD05_RS09220
uniprot id: A0A3T0D6T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1222016:ELD05 RS07390
gene id: 1222016:ELD05_RS07390
uniprot id: A0A3T0D624
names: Similarity
messages: Belongs to the asp23 family.

1222016:ELD05 RS07000
gene id: 1222016:ELD05_RS07000
uniprot id: A0A3T0D5Q6
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1222016:ELD05 RS05050
gene id: 1222016:ELD05_RS05050
uniprot id: A0A3T0D4U8
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1222016:ELD05 RS06930
gene id: 1222016:ELD05_RS06930
uniprot id: A0A3T0D5W3
names: Caution
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1222016:ELD05 RS05360
gene id: 1222016:ELD05_RS05360
uniprot id: A0A3T0D8X6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

1222016:ELD05 RS10940
gene id: 1222016:ELD05_RS10940
uniprot id: A0A3T0D807
names: Similarity
messages: Belongs to the EamA transporter family.

1222016:ELD05 RS08580
gene id: 1222016:ELD05_RS08580
uniprot id: A0A3T0D9E2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1222016:ELD05 RS04190
gene id: 1222016:ELD05_RS04190
uniprot id: A0A3T0D4D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1222016:ELD05 RS09910
gene id: 1222016:ELD05_RS09910
uniprot id: A0A3T0D731
names: Similarity
messages: Belongs to the GerABKA family.

1222016:ELD05 RS05730
gene id: 1222016:ELD05_RS05730
uniprot id: A0A3T0D544
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1222016:ELD05 RS05930
gene id: 1222016:ELD05_RS05930
uniprot id: A0A3T0D599
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1222016:ELD05 RS02190
gene id: 1222016:ELD05_RS02190
uniprot id: A0A3T0D3Y3
names: Similarity
messages: Belongs to the hemerythrin family.

1222016:ELD05 RS07610
gene id: 1222016:ELD05_RS07610
uniprot id: A0A3T0D6J0
names: Similarity
messages: Belongs to the SleB family.

1222016:ELD05 RS13125
gene id: 1222016:ELD05_RS13125
uniprot id: A0A3T0D8J7
names: Similarity
messages: Belongs to the P(II) protein family.

1222016:ELD05 RS04725
gene id: 1222016:ELD05_RS04725
uniprot id: A0A3T0D4P4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1222016:ELD05 RS06005
gene id: 1222016:ELD05_RS06005
uniprot id: A0A3T0D589
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1222016:ELD05 RS03035
gene id: 1222016:ELD05_RS03035
uniprot id: A0A3T0D363
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1222016:ELD05 RS02300
gene id: 1222016:ELD05_RS02300
uniprot id: A0A3T0D2U8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1222016:ELD05 RS06165
gene id: 1222016:ELD05_RS06165
uniprot id: A0A3T0D5H1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1222016:ELD05 RS07560
gene id: 1222016:ELD05_RS07560
uniprot id: A0A3T0D646
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1222016:ELD05 RS04785
gene id: 1222016:ELD05_RS04785
uniprot id: A0A3T0D4N4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1222016:ELD05 RS05065
gene id: 1222016:ELD05_RS05065
uniprot id: A0A3T0D4V0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1222016:ELD05 RS04740
gene id: 1222016:ELD05_RS04740
uniprot id: A0A3T0D4N3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1222016:ELD05 RS04730
gene id: 1222016:ELD05_RS04730
uniprot id: A0A3T0D4P7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1222016:ELD05 RS13755
gene id: 1222016:ELD05_RS13755
uniprot id: A0A3T0D8T7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1222016:ELD05 RS04750
gene id: 1222016:ELD05_RS04750
uniprot id: A0A3T0D4S1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1222016:ELD05 RS03140
gene id: 1222016:ELD05_RS03140
uniprot id: A0A3T0D370
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1222016:ELD05 RS05720
gene id: 1222016:ELD05_RS05720
uniprot id: A0A3T0D518
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1222016:ELD05 RS04705
gene id: 1222016:ELD05_RS04705
uniprot id: A0A3T0D4N6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1222016:ELD05 RS09330
gene id: 1222016:ELD05_RS09330
uniprot id: A0A3T0D786
names: Similarity
messages: Belongs to the CtsR family.

1222016:ELD05 RS05435
gene id: 1222016:ELD05_RS05435
uniprot id: A0A3T0D4Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

1222016:ELD05 RS04115
gene id: 1222016:ELD05_RS04115
uniprot id: A0A3T0D4D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

1222016:ELD05 RS11010
gene id: 1222016:ELD05_RS11010
uniprot id: A0A3T0D843
names: Similarity
messages: Belongs to the UPF0145 family.

1222016:ELD05 RS10120
gene id: 1222016:ELD05_RS10120
uniprot id: A0A3T0D7P2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1222016:ELD05 RS03580
gene id: 1222016:ELD05_RS03580
uniprot id: A0A3T0D3N9
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

1222016:ELD05 RS04690
gene id: 1222016:ELD05_RS04690
uniprot id: A0A3T0D4M1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1222016:ELD05 RS09985
gene id: 1222016:ELD05_RS09985
uniprot id: A0A3T0D791
names: Subcellular Location Annotation
messages: Membrane

1222016:ELD05 RS06335
gene id: 1222016:ELD05_RS06335
uniprot id: A0A3T0D5F0
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1222016:ELD05 RS08595
gene id: 1222016:ELD05_RS08595
uniprot id: A0A3T0D9J2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1222016:ELD05 RS03585
gene id: 1222016:ELD05_RS03585
uniprot id: A0A3T0D3V8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1222016:ELD05 RS03575
gene id: 1222016:ELD05_RS03575
uniprot id: A0A3T0D3H0
names: Similarity
messages: Belongs to the UPF0237 family.

1222016:ELD05 RS04645
gene id: 1222016:ELD05_RS04645
uniprot id: A0A3T0D4N1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1222016:ELD05 RS04625
gene id: 1222016:ELD05_RS04625
uniprot id: A0A3T0D4M8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1222016:ELD05 RS10110
gene id: 1222016:ELD05_RS10110
uniprot id: A0A3T0D792
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1222016:ELD05 RS07460
gene id: 1222016:ELD05_RS07460
uniprot id: A0A3T0D669
names: Similarity
messages: Belongs to the UPF0297 family.

1222016:ELD05 RS08610
gene id: 1222016:ELD05_RS08610
uniprot id: A0A3T0D6K9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1222016:ELD05 RS08430
gene id: 1222016:ELD05_RS08430
uniprot id: A0A3T0D6H9
names: Similarity
messages: Belongs to the UPF0473 family.

1222016:ELD05 RS09835
gene id: 1222016:ELD05_RS09835
uniprot id: A0A3T0D747
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1222016:ELD05 RS03830
gene id: 1222016:ELD05_RS03830
uniprot id: A0A3T0D486
names: Similarity
messages: Belongs to the P(II) protein family.

1222016:ELD05 RS02170
gene id: 1222016:ELD05_RS02170
uniprot id: A0A3T0D426
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1222016:ELD05 RS04500
gene id: 1222016:ELD05_RS04500
uniprot id: A0A3T0D4J8
names: Subcellular Location Annotation
messages: Membrane

1222016:ELD05 RS00290
gene id: 1222016:ELD05_RS00290
uniprot id: A0A3T0D3P3
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated Csm2 family.
messages: This subunit may be involved in monitoring complementarity of crRNA and target RNA.

1222016:ELD05 RS01350
gene id: 1222016:ELD05_RS01350
uniprot id: A0A3T0D2L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1222016:ELD05 RS04760
gene id: 1222016:ELD05_RS04760
uniprot id: A0A3T0D4N9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.