1215089:BBI08 RS13355
gene id: 1215089:BBI08_RS13355
uniprot id: A0A1C7DRH4
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS00795
gene id: 1215089:BBI08_RS00795
uniprot id: A0A1C7DSZ4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1215089:BBI08 RS13995
gene id: 1215089:BBI08_RS13995
uniprot id: A0A1C7DRT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1215089:BBI08 RS06185
gene id: 1215089:BBI08_RS06185
uniprot id: A0A1C7DMN3
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1215089:BBI08 RS13535
gene id: 1215089:BBI08_RS13535
uniprot id: A0A1C7DRK5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1215089:BBI08 RS00060
gene id: 1215089:BBI08_RS00060
uniprot id: A0A1C7DSM5
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1215089:BBI08 RS02270
gene id: 1215089:BBI08_RS02270
uniprot id: A0A1C7DTR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1215089:BBI08 RS16780
gene id: 1215089:BBI08_RS16780
uniprot id: A0A1C7DT43
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 535 of 16S rRNA.

1215089:BBI08 RS00470
gene id: 1215089:BBI08_RS00470
uniprot id: A0A1C7DTB4
names: Similarity
messages: Belongs to the CtsR family.

1215089:BBI08 RS06045
gene id: 1215089:BBI08_RS06045
uniprot id: A0A1C7DMH5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS07725
gene id: 1215089:BBI08_RS07725
uniprot id: A0A1C7DNK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1215089:BBI08 RS03015
gene id: 1215089:BBI08_RS03015
uniprot id: A0A1C7DV23
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS01160
gene id: 1215089:BBI08_RS01160
uniprot id: A0A1C7DU77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1215089:BBI08 RS11690
gene id: 1215089:BBI08_RS11690
uniprot id: A0A1C7DQ86
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1215089:BBI08 RS10165
gene id: 1215089:BBI08_RS10165
uniprot id: A0A1C7DP90
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.
messages: Cytoplasm

1215089:BBI08 RS05345
gene id: 1215089:BBI08_RS05345
uniprot id: A0A1C7DMS6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1215089:BBI08 RS01260
gene id: 1215089:BBI08_RS01260
uniprot id: A0A1C7DT75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS14205
gene id: 1215089:BBI08_RS14205
uniprot id: A0A1C7DSI5
names: Similarity
messages: Belongs to the peptidase M20A family.

1215089:BBI08 RS09095
gene id: 1215089:BBI08_RS09095
uniprot id: A0A1C7DP54
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS04645
gene id: 1215089:BBI08_RS04645
uniprot id: A0A1C7DMC2
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS14965
gene id: 1215089:BBI08_RS14965
uniprot id: A0A1C7DS01
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1215089:BBI08 RS06990
gene id: 1215089:BBI08_RS06990
uniprot id: A0A1C7DMS3
names: Similarity
messages: Belongs to the GSP E family.

1215089:BBI08 RS03230
gene id: 1215089:BBI08_RS03230
uniprot id: A0A1C7DVB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1215089:BBI08 RS01080
gene id: 1215089:BBI08_RS01080
uniprot id: A0A1C7DTT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1215089:BBI08 RS16260
gene id: 1215089:BBI08_RS16260
uniprot id: A0A1C7DT12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1215089:BBI08 RS05075
gene id: 1215089:BBI08_RS05075
uniprot id: A0A1C7DLL3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1215089:BBI08 RS13885
gene id: 1215089:BBI08_RS13885
uniprot id: A0A1C7DVS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS15170
gene id: 1215089:BBI08_RS15170
uniprot id: A0A1C7DVT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Membrane

1215089:BBI08 RS08870
gene id: 1215089:BBI08_RS08870
uniprot id: A0A1C7DNV9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1215089:BBI08 RS10330
gene id: 1215089:BBI08_RS10330
uniprot id: A0A1C7DPB2
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS11230
gene id: 1215089:BBI08_RS11230
uniprot id: A0A1C7DPP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1215089:BBI08 RS14310
gene id: 1215089:BBI08_RS14310
uniprot id: A0A1C7DRZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

1215089:BBI08 RS06825
gene id: 1215089:BBI08_RS06825
uniprot id: A0A1C7DMN7
names: Similarity
messages: Belongs to the thioredoxin family.

1215089:BBI08 RS09195
gene id: 1215089:BBI08_RS09195
uniprot id: A0A1C7DP75
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1215089:BBI08 RS00580
gene id: 1215089:BBI08_RS00580
uniprot id: A0A1C7DTJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1215089:BBI08 RS15255
gene id: 1215089:BBI08_RS15255
uniprot id: A0A1C7DRT3
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1215089:BBI08 RS07775
gene id: 1215089:BBI08_RS07775
uniprot id: A0A1C7DNB2
names: Similarity
messages: Belongs to the TlyA family.

1215089:BBI08 RS05000
gene id: 1215089:BBI08_RS05000
uniprot id: A0A1C7DM12
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1215089:BBI08 RS11045
gene id: 1215089:BBI08_RS11045
uniprot id: A0A1C7DQ12
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1215089:BBI08 RS08915
gene id: 1215089:BBI08_RS08915
uniprot id: A0A1C7DPL9
names: Similarity
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1215089:BBI08 RS06020
gene id: 1215089:BBI08_RS06020
uniprot id: A0A1C7DN29
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1215089:BBI08 RS04235
gene id: 1215089:BBI08_RS04235
uniprot id: A0A1C7DUT0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1215089:BBI08 RS12780
gene id: 1215089:BBI08_RS12780
uniprot id: A0A1C7DW26
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1215089:BBI08 RS07245
gene id: 1215089:BBI08_RS07245
uniprot id: A0A1C7DMX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1215089:BBI08 RS02290
gene id: 1215089:BBI08_RS02290
uniprot id: A0A1C7DUF4
names: Similarity
messages: Belongs to the P(II) protein family.

1215089:BBI08 RS00685
gene id: 1215089:BBI08_RS00685
uniprot id: A0A1C7DTU4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1215089:BBI08 RS05320
gene id: 1215089:BBI08_RS05320
uniprot id: A0A1C7DMC1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1215089:BBI08 RS08000
gene id: 1215089:BBI08_RS08000
uniprot id: A0A1C7DNJ9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
messages: Monomer.

1215089:BBI08 RS13820
gene id: 1215089:BBI08_RS13820
uniprot id: A0A1C7DRW2
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the octanoyltransferase LipL family.
messages: Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes.
messages: The reaction proceeds via a thioester-linked acyl-enzyme intermediate.

1215089:BBI08 RS06770
gene id: 1215089:BBI08_RS06770
uniprot id: A0A1C7DMR8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family. RnhC subfamily.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1215089:BBI08 RS08020
gene id: 1215089:BBI08_RS08020
uniprot id: A0A1C7DNZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1215089:BBI08 RS11235
gene id: 1215089:BBI08_RS11235
uniprot id: A0A1C7DQN8
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1215089:BBI08 RS00980
gene id: 1215089:BBI08_RS00980
uniprot id: A0A1C7DTR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1215089:BBI08 RS12605
gene id: 1215089:BBI08_RS12605
uniprot id: A0A1C7DR76
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1215089:BBI08 RS10890
gene id: 1215089:BBI08_RS10890
uniprot id: A0A1C7DPY0
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS13610
gene id: 1215089:BBI08_RS13610
uniprot id: A0A1C7DRM2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1215089:BBI08 RS07185
gene id: 1215089:BBI08_RS07185
uniprot id: A0A1C7DMZ7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1215089:BBI08 RS00775
gene id: 1215089:BBI08_RS00775
uniprot id: A0A1C7DTC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1215089:BBI08 RS14640
gene id: 1215089:BBI08_RS14640
uniprot id: A0A1C7DS63
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

1215089:BBI08 RS06480
gene id: 1215089:BBI08_RS06480
uniprot id: A0A1C7DMW2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1215089:BBI08 RS04385
gene id: 1215089:BBI08_RS04385
uniprot id: A0A1C7DM71
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1215089:BBI08 RS08970
gene id: 1215089:BBI08_RS08970
uniprot id: A0A1C7DPM7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1215089:BBI08 RS02640
gene id: 1215089:BBI08_RS02640
uniprot id: A0A1C7DUW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1215089:BBI08 RS08690
gene id: 1215089:BBI08_RS08690
uniprot id: A0A1C7DNE5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1215089:BBI08 RS04985
gene id: 1215089:BBI08_RS04985
uniprot id: A0A1C7DM32
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1215089:BBI08 RS09525
gene id: 1215089:BBI08_RS09525
uniprot id: A0A1C7DPD9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

1215089:BBI08 RS00725
gene id: 1215089:BBI08_RS00725
uniprot id: A0A1C7DTB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1215089:BBI08 RS06830
gene id: 1215089:BBI08_RS06830
uniprot id: A0A1C7DMW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1215089:BBI08 RS07555
gene id: 1215089:BBI08_RS07555
uniprot id: A0A1C7DN43
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1215089:BBI08 RS00920
gene id: 1215089:BBI08_RS00920
uniprot id: A0A1C7DTJ0
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

1215089:BBI08 RS07240
gene id: 1215089:BBI08_RS07240
uniprot id: A0A1C7DN07
names: Similarity
messages: Belongs to the UPF0297 family.

1215089:BBI08 RS02085
gene id: 1215089:BBI08_RS02085
uniprot id: A0A1C7DUC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1215089:BBI08 RS10230
gene id: 1215089:BBI08_RS10230
uniprot id: A0A1C7DPA0
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1215089:BBI08 RS00515
gene id: 1215089:BBI08_RS00515
uniprot id: A0A1C7DTI4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1215089:BBI08 RS11995
gene id: 1215089:BBI08_RS11995
uniprot id: A0A1C7DQJ2
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. YjcG family.

1215089:BBI08 RS14990
gene id: 1215089:BBI08_RS14990
uniprot id: A0A1C7DRN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS04005
gene id: 1215089:BBI08_RS04005
uniprot id: A0A1C7DV20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1215089:BBI08 RS15660
gene id: 1215089:BBI08_RS15660
uniprot id: A0A1C7DSW7
names: Function
names: Similarity
messages: Belongs to the NanE family.
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

1215089:BBI08 RS09390
gene id: 1215089:BBI08_RS09390
uniprot id: A0A1C7DNU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS10200
gene id: 1215089:BBI08_RS10200
uniprot id: A0A1C7DPH8
names: Similarity
names: Subunit
messages: Belongs to the MtrB family.
messages: Oligomer of 11 identical subunits arranged in doughnut-like structure.

1215089:BBI08 RS11040
gene id: 1215089:BBI08_RS11040
uniprot id: A0A1C7DQ82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1215089:BBI08 RS13680
gene id: 1215089:BBI08_RS13680
uniprot id: A0A1C7DRZ0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1215089:BBI08 RS14605
gene id: 1215089:BBI08_RS14605
uniprot id: A0A1C7DSG4
names: Similarity
messages: Belongs to the TelA family.

1215089:BBI08 RS04675
gene id: 1215089:BBI08_RS04675
uniprot id: A0A1C7DLW9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1215089:BBI08 RS03260
gene id: 1215089:BBI08_RS03260
uniprot id: A0A1C7DUY2
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

1215089:BBI08 RS05375
gene id: 1215089:BBI08_RS05375
uniprot id: A0A1C7DLR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1215089:BBI08 RS00770
gene id: 1215089:BBI08_RS00770
uniprot id: A0A1C7DTH0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1215089:BBI08 RS01050
gene id: 1215089:BBI08_RS01050
uniprot id: A0A1C7DU57
names: Similarity
messages: Belongs to the FlgM family.

1215089:BBI08 RS07820
gene id: 1215089:BBI08_RS07820
uniprot id: A0A1C7DP12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

1215089:BBI08 RS01605
gene id: 1215089:BBI08_RS01605
uniprot id: A0A1C7DTS4
names: Similarity
messages: Belongs to the peptidase C40 family.

1215089:BBI08 RS03085
gene id: 1215089:BBI08_RS03085
uniprot id: A0A1C7DUU7
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS03985
gene id: 1215089:BBI08_RS03985
uniprot id: A0A1C7DVC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1215089:BBI08 RS06900
gene id: 1215089:BBI08_RS06900
uniprot id: A0A1C7DMI1
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1215089:BBI08 RS01955
gene id: 1215089:BBI08_RS01955
uniprot id: A0A1C7DTK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1215089:BBI08 RS05325
gene id: 1215089:BBI08_RS05325
uniprot id: A0A1C7DLR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1215089:BBI08 RS00765
gene id: 1215089:BBI08_RS00765
uniprot id: A0A1C7DTN9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1215089:BBI08 RS14695
gene id: 1215089:BBI08_RS14695
uniprot id: A0A1C7DWB2
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS16205
gene id: 1215089:BBI08_RS16205
uniprot id: A0A1C7DVH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylthioribose kinase family.
messages: Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.
messages: Homodimer.

1215089:BBI08 RS12025
gene id: 1215089:BBI08_RS12025
uniprot id: A0A1C7DR38
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS01940
gene id: 1215089:BBI08_RS01940
uniprot id: A0A1C7DU90
names: Similarity
messages: Belongs to the UPF0178 family.

1215089:BBI08 RS11035
gene id: 1215089:BBI08_RS11035
uniprot id: A0A1C7DQT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor.

1215089:BBI08 RS00640
gene id: 1215089:BBI08_RS00640
uniprot id: A0A1C7DT10
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1215089:BBI08 RS02985
gene id: 1215089:BBI08_RS02985
uniprot id: A0A1C7DUS8
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS00655
gene id: 1215089:BBI08_RS00655
uniprot id: A0A1C7DTL6
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS06790
gene id: 1215089:BBI08_RS06790
uniprot id: A0A1C7DMG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

1215089:BBI08 RS14305
gene id: 1215089:BBI08_RS14305
uniprot id: A0A1C7DSK6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

1215089:BBI08 RS07455
gene id: 1215089:BBI08_RS07455
uniprot id: A0A1C7DN22
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1215089:BBI08 RS11430
gene id: 1215089:BBI08_RS11430
uniprot id: A0A1C7DQD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1215089:BBI08 RS07755
gene id: 1215089:BBI08_RS07755
uniprot id: A0A1C7DNH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1215089:BBI08 RS02480
gene id: 1215089:BBI08_RS02480
uniprot id: A0A1C7DUI3
names: Similarity
messages: Belongs to the CvfB family.

1215089:BBI08 RS14090
gene id: 1215089:BBI08_RS14090
uniprot id: A0A1C7DR62
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

1215089:BBI08 RS06665
gene id: 1215089:BBI08_RS06665
uniprot id: A0A1C7DMW7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1215089:BBI08 RS13325
gene id: 1215089:BBI08_RS13325
uniprot id: A0A1C7DRR3
names: Similarity
messages: Belongs to the peptidase S8 family.

1215089:BBI08 RS06250
gene id: 1215089:BBI08_RS06250
uniprot id: A0A1C7DMP0
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1215089:BBI08 RS03120
gene id: 1215089:BBI08_RS03120
uniprot id: A0A1C7DUA9
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1215089:BBI08 RS15475
gene id: 1215089:BBI08_RS15475
uniprot id: A0A1C7DT77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1215089:BBI08 RS04725
gene id: 1215089:BBI08_RS04725
uniprot id: A0A1C7DLX8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1215089:BBI08 RS07970
gene id: 1215089:BBI08_RS07970
uniprot id: A0A1C7DNY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1215089:BBI08 RS04255
gene id: 1215089:BBI08_RS04255
uniprot id: A0A1C7DVH0
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1215089:BBI08 RS10410
gene id: 1215089:BBI08_RS10410
uniprot id: A0A1C7DPP2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1215089:BBI08 RS00670
gene id: 1215089:BBI08_RS00670
uniprot id: A0A1C7DTE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1215089:BBI08 RS11675
gene id: 1215089:BBI08_RS11675
uniprot id: A0A1C7DR54
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1215089:BBI08 RS04770
gene id: 1215089:BBI08_RS04770
uniprot id: A0A1C7DLQ2
names: Similarity
messages: Belongs to the Fur family.

1215089:BBI08 RS01745
gene id: 1215089:BBI08_RS01745
uniprot id: A0A1C7DUP5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1215089:BBI08 RS11820
gene id: 1215089:BBI08_RS11820
uniprot id: A0A1C7DQL7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1215089:BBI08 RS12685
gene id: 1215089:BBI08_RS12685
uniprot id: A0A1C7DRP0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1215089:BBI08 RS13670
gene id: 1215089:BBI08_RS13670
uniprot id: A0A1C7DR35
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS16745
gene id: 1215089:BBI08_RS16745
uniprot id: A0A1C7DVR4
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1215089:BBI08 RS15995
gene id: 1215089:BBI08_RS15995
uniprot id: A0A1C7DSW2
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1215089:BBI08 RS11255
gene id: 1215089:BBI08_RS11255
uniprot id: A0A1C7DQ55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1215089:BBI08 RS09110
gene id: 1215089:BBI08_RS09110
uniprot id: A0A1C7DNZ6
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS07165
gene id: 1215089:BBI08_RS07165
uniprot id: A0A1C7DNJ7
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1215089:BBI08 RS04580
gene id: 1215089:BBI08_RS04580
uniprot id: A0A1C7DLF1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1215089:BBI08 RS07385
gene id: 1215089:BBI08_RS07385
uniprot id: A0A1C7DNT1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1215089:BBI08 RS01170
gene id: 1215089:BBI08_RS01170
uniprot id: A0A1C7DUF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1215089:BBI08 RS03570
gene id: 1215089:BBI08_RS03570
uniprot id: A0A1C7DV33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1215089:BBI08 RS09325
gene id: 1215089:BBI08_RS09325
uniprot id: A0A1C7DP10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1215089:BBI08 RS16545
gene id: 1215089:BBI08_RS16545
uniprot id: A0A1C7DT61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1215089:BBI08 RS08925
gene id: 1215089:BBI08_RS08925
uniprot id: A0A1C7DNW9
names: Cofactor
messages: Can also use Mn(2+) ion.

1215089:BBI08 RS07530
gene id: 1215089:BBI08_RS07530
uniprot id: A0A1C7DNQ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1215089:BBI08 RS05985
gene id: 1215089:BBI08_RS05985
uniprot id: A0A1C7DMG5
names: Similarity
messages: Belongs to the isochorismate synthase family.

1215089:BBI08 RS06580
gene id: 1215089:BBI08_RS06580
uniprot id: A0A1C7DMS1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS16400
gene id: 1215089:BBI08_RS16400
uniprot id: A0A1C7DSE2
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1215089:BBI08 RS06640
gene id: 1215089:BBI08_RS06640
uniprot id: A0A1C7DMD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1215089:BBI08 RS00510
gene id: 1215089:BBI08_RS00510
uniprot id: A0A1C7DU36
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1215089:BBI08 RS11135
gene id: 1215089:BBI08_RS11135
uniprot id: A0A1C7DQN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1215089:BBI08 RS07290
gene id: 1215089:BBI08_RS07290
uniprot id: A0A1C7DN85
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

1215089:BBI08 RS00055
gene id: 1215089:BBI08_RS00055
uniprot id: A0A1C7DSS1
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1215089:BBI08 RS11610
gene id: 1215089:BBI08_RS11610
uniprot id: A0A1C7DQV8
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS06585
gene id: 1215089:BBI08_RS06585
uniprot id: A0A1C7DMY0
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

1215089:BBI08 RS00500
gene id: 1215089:BBI08_RS00500
uniprot id: A0A1C7DTW1
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1215089:BBI08 RS06215
gene id: 1215089:BBI08_RS06215
uniprot id: A0A1C7DMK0
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1215089:BBI08 RS15560
gene id: 1215089:BBI08_RS15560
uniprot id: A0A1C7DS49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1215089:BBI08 RS09470
gene id: 1215089:BBI08_RS09470
uniprot id: A0A1C7DPC9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1215089:BBI08 RS01060
gene id: 1215089:BBI08_RS01060
uniprot id: A0A1C7DUD4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1215089:BBI08 RS07140
gene id: 1215089:BBI08_RS07140
uniprot id: A0A1C7DMW0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1215089:BBI08 RS08480
gene id: 1215089:BBI08_RS08480
uniprot id: A0A1C7DNV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS15795
gene id: 1215089:BBI08_RS15795
uniprot id: A0A1C7DTD2
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1215089:BBI08 RS10435
gene id: 1215089:BBI08_RS10435
uniprot id: A0A1C7DPB0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1215089:BBI08 RS08030
gene id: 1215089:BBI08_RS08030
uniprot id: A0A1C7DP53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase family. ParE type 2 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1215089:BBI08 RS06505
gene id: 1215089:BBI08_RS06505
uniprot id: A0A1C7DNC0
names: Similarity
messages: Belongs to the YjdM family.

1215089:BBI08 RS05980
gene id: 1215089:BBI08_RS05980
uniprot id: A0A1C7DM82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1215089:BBI08 RS12825
gene id: 1215089:BBI08_RS12825
uniprot id: A0A1C7DRC0
names: Similarity
messages: Belongs to the CpsD/CapB family.

1215089:BBI08 RS09490
gene id: 1215089:BBI08_RS09490
uniprot id: A0A1C7DP40
names: Similarity
messages: Belongs to the thioredoxin family.

1215089:BBI08 RS12435
gene id: 1215089:BBI08_RS12435
uniprot id: A0A1C7DR02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1215089:BBI08 RS15965
gene id: 1215089:BBI08_RS15965
uniprot id: A0A1C7DSJ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1215089:BBI08 RS14135
gene id: 1215089:BBI08_RS14135
uniprot id: A0A1C7DRB8
names: Subcellular Location Annotation
messages: Cell membrane

1215089:BBI08 RS07525
gene id: 1215089:BBI08_RS07525
uniprot id: A0A1C7DMT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. CshB subfamily.
messages: Cytoplasm
messages: Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures.

1215089:BBI08 RS04020
gene id: 1215089:BBI08_RS04020
uniprot id: A0A1C7DUV1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1215089:BBI08 RS01310
gene id: 1215089:BBI08_RS01310
uniprot id: A0A1C7DT86
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS07325
gene id: 1215089:BBI08_RS07325
uniprot id: A0A1C7DNL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1215089:BBI08 RS09750
gene id: 1215089:BBI08_RS09750
uniprot id: A0A1C7DNY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS12275
gene id: 1215089:BBI08_RS12275
uniprot id: A0A1C7DR15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1215089:BBI08 RS10795
gene id: 1215089:BBI08_RS10795
uniprot id: A0A1C7DQ11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1215089:BBI08 RS10155
gene id: 1215089:BBI08_RS10155
uniprot id: A0A1C7DPP3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1215089:BBI08 RS00940
gene id: 1215089:BBI08_RS00940
uniprot id: A0A1C7DT62
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1215089:BBI08 RS12595
gene id: 1215089:BBI08_RS12595
uniprot id: A0A1C7DQQ2
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1215089:BBI08 RS16380
gene id: 1215089:BBI08_RS16380
uniprot id: A0A1C7DSS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1215089:BBI08 RS01550
gene id: 1215089:BBI08_RS01550
uniprot id: A0A1C7DTV6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1215089:BBI08 RS07130
gene id: 1215089:BBI08_RS07130
uniprot id: A0A1C7DN61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1215089:BBI08 RS10225
gene id: 1215089:BBI08_RS10225
uniprot id: A0A1C7DPX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1215089:BBI08 RS16100
gene id: 1215089:BBI08_RS16100
uniprot id: A0A1C7DSY6
names: Similarity
messages: Belongs to the FGGY kinase family.

1215089:BBI08 RS01540
gene id: 1215089:BBI08_RS01540
uniprot id: A0A1C7DU18
names: Similarity
messages: Belongs to the peptidase S8 family.

1215089:BBI08 RS01535
gene id: 1215089:BBI08_RS01535
uniprot id: A0A1C7DUL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1215089:BBI08 RS13930
gene id: 1215089:BBI08_RS13930
uniprot id: A0A1C7DR77
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. YrrT family.
messages: Could be a S-adenosyl-L-methionine-dependent methyltransferase.

1215089:BBI08 RS03600
gene id: 1215089:BBI08_RS03600
uniprot id: A0A1C7DUG1
names: Similarity
messages: Belongs to the glutamate synthase family.

1215089:BBI08 RS07830
gene id: 1215089:BBI08_RS07830
uniprot id: A0A1C7DNC2
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

1215089:BBI08 RS00485
gene id: 1215089:BBI08_RS00485
uniprot id: A0A1C7DTQ7
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1215089:BBI08 RS14345
gene id: 1215089:BBI08_RS14345
uniprot id: A0A1C7DRA6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1215089:BBI08 RS12795
gene id: 1215089:BBI08_RS12795
uniprot id: A0A1C7DR69
names: Function
messages: Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA.

1215089:BBI08 RS12515
gene id: 1215089:BBI08_RS12515
uniprot id: A0A1C7DRC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

1215089:BBI08 RS12880
gene id: 1215089:BBI08_RS12880
uniprot id: A0A1C7DQL9
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS11015
gene id: 1215089:BBI08_RS11015
uniprot id: A0A1C7DPM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1215089:BBI08 RS10080
gene id: 1215089:BBI08_RS10080
uniprot id: A0A1C7DPP8
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS05035
gene id: 1215089:BBI08_RS05035
uniprot id: A0A1C7DM37
names: Function
messages: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.

1215089:BBI08 RS03025
gene id: 1215089:BBI08_RS03025
uniprot id: A0A1C7DU52
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

1215089:BBI08 RS12205
gene id: 1215089:BBI08_RS12205
uniprot id: A0A1C7DQM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

1215089:BBI08 RS08435
gene id: 1215089:BBI08_RS08435
uniprot id: A0A1C7DPC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1215089:BBI08 RS00585
gene id: 1215089:BBI08_RS00585
uniprot id: A0A1C7DTS5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1215089:BBI08 RS16315
gene id: 1215089:BBI08_RS16315
uniprot id: A0A1C7DTN1
names: Function
names: Similarity
messages: Belongs to the LarC family.
messages: Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes.

1215089:BBI08 RS04085
gene id: 1215089:BBI08_RS04085
uniprot id: A0A1C7DVE4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1215089:BBI08 RS13410
gene id: 1215089:BBI08_RS13410
uniprot id: A0A1C7DRN1
names: Similarity
messages: Belongs to the EamA transporter family.

1215089:BBI08 RS10370
gene id: 1215089:BBI08_RS10370
uniprot id: A0A1C7DPT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

1215089:BBI08 RS13385
gene id: 1215089:BBI08_RS13385
uniprot id: A0A1C7DS20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS06295
gene id: 1215089:BBI08_RS06295
uniprot id: A0A1C7DN79
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1215089:BBI08 RS11030
gene id: 1215089:BBI08_RS11030
uniprot id: A0A1C7DQ78
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1215089:BBI08 RS03665
gene id: 1215089:BBI08_RS03665
uniprot id: A0A1C7DV54
names: Similarity
messages: Belongs to the CdaR family.

1215089:BBI08 RS01305
gene id: 1215089:BBI08_RS01305
uniprot id: A0A1C7DTD0
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS13145
gene id: 1215089:BBI08_RS13145
uniprot id: A0A1C7DRD4
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1215089:BBI08 RS03705
gene id: 1215089:BBI08_RS03705
uniprot id: A0A1C7DUI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS06650
gene id: 1215089:BBI08_RS06650
uniprot id: A0A1C7DN95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1215089:BBI08 RS13795
gene id: 1215089:BBI08_RS13795
uniprot id: A0A1C7DSA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

1215089:BBI08 RS02675
gene id: 1215089:BBI08_RS02675
uniprot id: A0A1C7DV69
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1215089:BBI08 RS07390
gene id: 1215089:BBI08_RS07390
uniprot id: A0A1C7DNA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1215089:BBI08 RS15365
gene id: 1215089:BBI08_RS15365
uniprot id: A0A1C7DSW9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1215089:BBI08 RS06910
gene id: 1215089:BBI08_RS06910
uniprot id: A0A1C7DNE9
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1215089:BBI08 RS00505
gene id: 1215089:BBI08_RS00505
uniprot id: A0A1C7DTI8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS01375
gene id: 1215089:BBI08_RS01375
uniprot id: A0A1C7DTZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

1215089:BBI08 RS07315
gene id: 1215089:BBI08_RS07315
uniprot id: A0A1C7DMR4
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1215089:BBI08 RS08905
gene id: 1215089:BBI08_RS08905
uniprot id: A0A1C7DPF3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1215089:BBI08 RS13940
gene id: 1215089:BBI08_RS13940
uniprot id: A0A1C7DS38
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1215089:BBI08 RS00635
gene id: 1215089:BBI08_RS00635
uniprot id: A0A1C7DTT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1215089:BBI08 RS10310
gene id: 1215089:BBI08_RS10310
uniprot id: A0A1C7DPM2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1215089:BBI08 RS07050
gene id: 1215089:BBI08_RS07050
uniprot id: A0A1C7DN69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1215089:BBI08 RS13290
gene id: 1215089:BBI08_RS13290
uniprot id: A0A1C7DRE3
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS04030
gene id: 1215089:BBI08_RS04030
uniprot id: A0A1C7DVS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS02865
gene id: 1215089:BBI08_RS02865
uniprot id: A0A1C7DUZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS16800
gene id: 1215089:BBI08_RS16800
uniprot id: A0A1C7DSR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
messages: Cell membrane
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.

1215089:BBI08 RS16725
gene id: 1215089:BBI08_RS16725
uniprot id: A0A1C7DT29
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1215089:BBI08 RS07810
gene id: 1215089:BBI08_RS07810
uniprot id: A0A1C7DNV8
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1215089:BBI08 RS10780
gene id: 1215089:BBI08_RS10780
uniprot id: A0A1C7DQ31
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

1215089:BBI08 RS11115
gene id: 1215089:BBI08_RS11115
uniprot id: A0A1C7DQE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

1215089:BBI08 RS16120
gene id: 1215089:BBI08_RS16120
uniprot id: A0A1C7DSM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1215089:BBI08 RS11595
gene id: 1215089:BBI08_RS11595
uniprot id: A0A1C7DPY4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Interacts with CtaA.
messages: Membrane

1215089:BBI08 RS16785
gene id: 1215089:BBI08_RS16785
uniprot id: A0A1C7DT02
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1215089:BBI08 RS10850
gene id: 1215089:BBI08_RS10850
uniprot id: A0A1C7DQ93
names: Similarity
messages: Belongs to the CinA family.

1215089:BBI08 RS00820
gene id: 1215089:BBI08_RS00820
uniprot id: A0A1C7DTI0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS03155
gene id: 1215089:BBI08_RS03155
uniprot id: A0A1C7DUL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS16520
gene id: 1215089:BBI08_RS16520
uniprot id: A0A1C7DTJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1215089:BBI08 RS07340
gene id: 1215089:BBI08_RS07340
uniprot id: A0A1C7DN96
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1215089:BBI08 RS07370
gene id: 1215089:BBI08_RS07370
uniprot id: A0A1C7DMQ7
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1215089:BBI08 RS00305
gene id: 1215089:BBI08_RS00305
uniprot id: A0A1C7DSR3
names: Similarity
messages: Belongs to the CarB family.

1215089:BBI08 RS11385
gene id: 1215089:BBI08_RS11385
uniprot id: A0A1C7DQK3
names: Similarity
messages: Belongs to the YggT family.

1215089:BBI08 RS08495
gene id: 1215089:BBI08_RS08495
uniprot id: A0A1C7DNP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family. Thioredoxin-coupled ArsC subfamily.
messages: Catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)].
messages: Cytoplasm

1215089:BBI08 RS05660
gene id: 1215089:BBI08_RS05660
uniprot id: A0A1C7DMC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS07715
gene id: 1215089:BBI08_RS07715
uniprot id: A0A1C7DN66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1215089:BBI08 RS06225
gene id: 1215089:BBI08_RS06225
uniprot id: A0A1C7DM44
names: Similarity
messages: Belongs to the universal stress protein A family.

1215089:BBI08 RS00090
gene id: 1215089:BBI08_RS00090
uniprot id: A0A1C7DT63
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS09030
gene id: 1215089:BBI08_RS09030
uniprot id: A0A1C7DNK4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS14400
gene id: 1215089:BBI08_RS14400
uniprot id: A0A1C7DSC4
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS16295
gene id: 1215089:BBI08_RS16295
uniprot id: A0A1C7DSH0
names: Similarity
messages: Belongs to the IlvD/Edd family.

1215089:BBI08 RS00005
gene id: 1215089:BBI08_RS00005
uniprot id: A0A1C7DTB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1215089:BBI08 RS10185
gene id: 1215089:BBI08_RS10185
uniprot id: A0A1C7DQC2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1215089:BBI08 RS03285
gene id: 1215089:BBI08_RS03285
uniprot id: A0A1C7DUY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

1215089:BBI08 RS05615
gene id: 1215089:BBI08_RS05615
uniprot id: A0A1C7DMH0
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1215089:BBI08 RS07825
gene id: 1215089:BBI08_RS07825
uniprot id: A0A1C7DNI6
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1215089:BBI08 RS12090
gene id: 1215089:BBI08_RS12090
uniprot id: A0A1C7DRD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS07890
gene id: 1215089:BBI08_RS07890
uniprot id: A0A1C7DNA1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1215089:BBI08 RS04285
gene id: 1215089:BBI08_RS04285
uniprot id: A0A1C7DLB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS08050
gene id: 1215089:BBI08_RS08050
uniprot id: A0A1C7DVG8
names: Similarity
messages: Belongs to the FBPase class 3 family.

1215089:BBI08 RS00030
gene id: 1215089:BBI08_RS00030
uniprot id: A0A1C7DTB9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1215089:BBI08 RS00750
gene id: 1215089:BBI08_RS00750
uniprot id: A0A1C7DU14
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1215089:BBI08 RS12110
gene id: 1215089:BBI08_RS12110
uniprot id: A0A1C7DQU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1215089:BBI08 RS00565
gene id: 1215089:BBI08_RS00565
uniprot id: A0A1C7DTJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1215089:BBI08 RS07460
gene id: 1215089:BBI08_RS07460
uniprot id: A0A1C7DN92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1215089:BBI08 RS05595
gene id: 1215089:BBI08_RS05595
uniprot id: A0A1C7DMD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS00100
gene id: 1215089:BBI08_RS00100
uniprot id: A0A1C7DTC3
names: Similarity
messages: Belongs to the DCK/DGK family.

1215089:BBI08 RS13495
gene id: 1215089:BBI08_RS13495
uniprot id: A0A1C7DRI6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS10000
gene id: 1215089:BBI08_RS10000
uniprot id: A0A1C7DPE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GpsB family.
messages: Cytoplasm
messages: Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.
messages: Forms polymers through the coiled coil domains. Interacts with PBP1, MreC and EzrA.

1215089:BBI08 RS13445
gene id: 1215089:BBI08_RS13445
uniprot id: A0A1C7DRH2
names: Similarity
messages: Belongs to the peptidase S66 family.

1215089:BBI08 RS03835
gene id: 1215089:BBI08_RS03835
uniprot id: A0A1C7DV48
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS16250
gene id: 1215089:BBI08_RS16250
uniprot id: A0A1C7DSB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1215089:BBI08 RS01230
gene id: 1215089:BBI08_RS01230
uniprot id: A0A1C7DTW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS16275
gene id: 1215089:BBI08_RS16275
uniprot id: A0A1C7DSV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS02670
gene id: 1215089:BBI08_RS02670
uniprot id: A0A1C7DUN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1215089:BBI08 RS10925
gene id: 1215089:BBI08_RS10925
uniprot id: A0A1C7DQJ4
names: Similarity
messages: Belongs to the peptidase M16 family.

1215089:BBI08 RS01970
gene id: 1215089:BBI08_RS01970
uniprot id: A0A1C7DUU6
names: Subcellular Location Annotation
messages: Cell membrane

1215089:BBI08 RS01130
gene id: 1215089:BBI08_RS01130
uniprot id: A0A1C7DTI5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1215089:BBI08 RS12730
gene id: 1215089:BBI08_RS12730
uniprot id: A0A1C7DQG8
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

1215089:BBI08 RS00600
gene id: 1215089:BBI08_RS00600
uniprot id: A0A1C7DTY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1215089:BBI08 RS07980
gene id: 1215089:BBI08_RS07980
uniprot id: A0A1C7DP48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1215089:BBI08 RS12340
gene id: 1215089:BBI08_RS12340
uniprot id: A0A1C7DQB9
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS15075
gene id: 1215089:BBI08_RS15075
uniprot id: A0A1C7DSE5
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1215089:BBI08 RS07445
gene id: 1215089:BBI08_RS07445
uniprot id: A0A1C7DNC3
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1215089:BBI08 RS11815
gene id: 1215089:BBI08_RS11815
uniprot id: A0A1C7DQZ9
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family. DapH subfamily.
messages: Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.

1215089:BBI08 RS16405
gene id: 1215089:BBI08_RS16405
uniprot id: A0A1C7DTH3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1215089:BBI08 RS07785
gene id: 1215089:BBI08_RS07785
uniprot id: A0A1C7DNF1
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1215089:BBI08 RS06875
gene id: 1215089:BBI08_RS06875
uniprot id: A0A1C7DMQ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1215089:BBI08 RS13175
gene id: 1215089:BBI08_RS13175
uniprot id: A0A1C7DRX9
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1215089:BBI08 RS06895
gene id: 1215089:BBI08_RS06895
uniprot id: A0A1C7DN41
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1215089:BBI08 RS13275
gene id: 1215089:BBI08_RS13275
uniprot id: A0A1C7DRQ3
names: Similarity
messages: Belongs to the acyltransferase 3 family.

1215089:BBI08 RS07365
gene id: 1215089:BBI08_RS07365
uniprot id: A0A1C7DMS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1215089:BBI08 RS00150
gene id: 1215089:BBI08_RS00150
uniprot id: A0A1C7DTE0
names: Similarity
messages: Belongs to the GppA/Ppx family.

1215089:BBI08 RS15840
gene id: 1215089:BBI08_RS15840
uniprot id: A0A1C7DVT2
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS08565
gene id: 1215089:BBI08_RS08565
uniprot id: A0A1C7DNQ6
names: Similarity
messages: Belongs to the EamA transporter family.

1215089:BBI08 RS02165
gene id: 1215089:BBI08_RS02165
uniprot id: A0A1C7DTT7
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

1215089:BBI08 RS07000
gene id: 1215089:BBI08_RS07000
uniprot id: A0A1C7DN63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS02430
gene id: 1215089:BBI08_RS02430
uniprot id: A0A1C7DUS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1215089:BBI08 RS13245
gene id: 1215089:BBI08_RS13245
uniprot id: A0A1C7DR60
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS14725
gene id: 1215089:BBI08_RS14725
uniprot id: A0A1C7DRH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

1215089:BBI08 RS14105
gene id: 1215089:BBI08_RS14105
uniprot id: A0A1C7DSG3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1215089:BBI08 RS10145
gene id: 1215089:BBI08_RS10145
uniprot id: A0A1C7DPJ3
names: Similarity
messages: Belongs to the UPF0302 family.

1215089:BBI08 RS07580
gene id: 1215089:BBI08_RS07580
uniprot id: A0A1C7DNR8
names: Similarity
messages: Belongs to the transpeptidase family.

1215089:BBI08 RS15865
gene id: 1215089:BBI08_RS15865
uniprot id: A0A1C7DSH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS14900
gene id: 1215089:BBI08_RS14900
uniprot id: A0A1C7DSW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS10920
gene id: 1215089:BBI08_RS10920
uniprot id: A0A1C7DPJ2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS05765
gene id: 1215089:BBI08_RS05765
uniprot id: A0A1C7DM62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Membrane

1215089:BBI08 RS07790
gene id: 1215089:BBI08_RS07790
uniprot id: A0A1C7DNL6
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with Spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. Repressor of abrB, activator of the spoIIa operon. Binds the DNA sequence 5'-TGNCGAA-3' (0A box).
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1215089:BBI08 RS12255
gene id: 1215089:BBI08_RS12255
uniprot id: A0A1C7DQP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1215089:BBI08 RS10960
gene id: 1215089:BBI08_RS10960
uniprot id: A0A1C7DQB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1215089:BBI08 RS04605
gene id: 1215089:BBI08_RS04605
uniprot id: A0A1C7DLY1
names: Similarity
messages: Belongs to the peptidase M29 family.

1215089:BBI08 RS02735
gene id: 1215089:BBI08_RS02735
uniprot id: A0A1C7DUN7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SprT family.
messages: Binds 1 zinc ion.
messages: Cytoplasm

1215089:BBI08 RS10910
gene id: 1215089:BBI08_RS10910
uniprot id: A0A1C7DQA5
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

1215089:BBI08 RS15595
gene id: 1215089:BBI08_RS15595
uniprot id: A0A1C7DSD1
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS07690
gene id: 1215089:BBI08_RS07690
uniprot id: A0A1C7DNG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1215089:BBI08 RS03225
gene id: 1215089:BBI08_RS03225
uniprot id: A0A1C7DU93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1215089:BBI08 RS11350
gene id: 1215089:BBI08_RS11350
uniprot id: A0A1C7DQR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1215089:BBI08 RS04475
gene id: 1215089:BBI08_RS04475
uniprot id: A0A1C7DLY0
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1215089:BBI08 RS10210
gene id: 1215089:BBI08_RS10210
uniprot id: A0A1C7DPQ5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1215089:BBI08 RS05335
gene id: 1215089:BBI08_RS05335
uniprot id: A0A1C7DMM6
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1215089:BBI08 RS09200
gene id: 1215089:BBI08_RS09200
uniprot id: A0A1C7DPR9
names: Similarity
messages: Belongs to the peptidase S41A family.

1215089:BBI08 RS12540
gene id: 1215089:BBI08_RS12540
uniprot id: A0A1C7DQP6
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1215089:BBI08 RS11110
gene id: 1215089:BBI08_RS11110
uniprot id: A0A1C7DQ74
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1215089:BBI08 RS15140
gene id: 1215089:BBI08_RS15140
uniprot id: A0A1C7DRX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS04200
gene id: 1215089:BBI08_RS04200
uniprot id: A0A1C7DVC3
names: Similarity
messages: Belongs to the peptidase S8 family.

1215089:BBI08 RS16495
gene id: 1215089:BBI08_RS16495
uniprot id: A0A1C7DT59
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1215089:BBI08 RS06820
gene id: 1215089:BBI08_RS06820
uniprot id: A0A1C7DMS8
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1215089:BBI08 RS13890
gene id: 1215089:BBI08_RS13890
uniprot id: A0A1C7DS28
names: Subcellular Location Annotation
messages: Cell membrane

1215089:BBI08 RS13310
gene id: 1215089:BBI08_RS13310
uniprot id: A0A1C7DRL1
names: Similarity
messages: Belongs to the peptidase S8 family.

1215089:BBI08 RS06970
gene id: 1215089:BBI08_RS06970
uniprot id: A0A1C7DN25
names: Function
messages: Required for transformation and DNA binding.

1215089:BBI08 RS07880
gene id: 1215089:BBI08_RS07880
uniprot id: A0A1C7DNJ2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1215089:BBI08 RS09600
gene id: 1215089:BBI08_RS09600
uniprot id: A0A1C7DP87
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS14820
gene id: 1215089:BBI08_RS14820
uniprot id: A0A1C7DS93
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1215089:BBI08 RS10825
gene id: 1215089:BBI08_RS10825
uniprot id: A0A1C7DQP5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1215089:BBI08 RS01180
gene id: 1215089:BBI08_RS01180
uniprot id: A0A1C7DTP0
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

1215089:BBI08 RS13740
gene id: 1215089:BBI08_RS13740
uniprot id: A0A1C7DS90
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1215089:BBI08 RS07125
gene id: 1215089:BBI08_RS07125
uniprot id: A0A1C7DNN5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1215089:BBI08 RS15835
gene id: 1215089:BBI08_RS15835
uniprot id: A0A1C7DT66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS04955
gene id: 1215089:BBI08_RS04955
uniprot id: A0A1C7DM52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS08800
gene id: 1215089:BBI08_RS08800
uniprot id: A0A1C7DPD7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1215089:BBI08 RS11295
gene id: 1215089:BBI08_RS11295
uniprot id: A0A1C7DQR0
names: Similarity
messages: Belongs to the serine/threonine dehydratase family. DsdA subfamily.

1215089:BBI08 RS03890
gene id: 1215089:BBI08_RS03890
uniprot id: A0A1C7DV99
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1215089:BBI08 RS11065
gene id: 1215089:BBI08_RS11065
uniprot id: A0A1C7DPN8
names: Similarity
messages: Belongs to the DprA/Smf family.

1215089:BBI08 RS13380
gene id: 1215089:BBI08_RS13380
uniprot id: A0A1C7DRI0
names: Similarity
messages: Belongs to the peptidase C40 family.

1215089:BBI08 RS00705
gene id: 1215089:BBI08_RS00705
uniprot id: A0A1C7DTM4
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1215089:BBI08 RS11700
gene id: 1215089:BBI08_RS11700
uniprot id: A0A1C7DQQ9
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1215089:BBI08 RS15165
gene id: 1215089:BBI08_RS15165
uniprot id: A0A1C7DSG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
messages: Membrane

1215089:BBI08 RS12085
gene id: 1215089:BBI08_RS12085
uniprot id: A0A1C7DQU2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1215089:BBI08 RS08540
gene id: 1215089:BBI08_RS08540
uniprot id: A0A1C7DP89
names: Similarity
messages: Belongs to the peptidase S51 family.

1215089:BBI08 RS16500
gene id: 1215089:BBI08_RS16500
uniprot id: A0A1C7DTC4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1215089:BBI08 RS06440
gene id: 1215089:BBI08_RS06440
uniprot id: A0A1C7DM83
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

1215089:BBI08 RS07695
gene id: 1215089:BBI08_RS07695
uniprot id: A0A1C7DNZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1215089:BBI08 RS11755
gene id: 1215089:BBI08_RS11755
uniprot id: A0A1C7DQ15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS00250
gene id: 1215089:BBI08_RS00250
uniprot id: A0A1C7DSQ3
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

1215089:BBI08 RS05755
gene id: 1215089:BBI08_RS05755
uniprot id: A0A1C7DMG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS16270
gene id: 1215089:BBI08_RS16270
uniprot id: A0A1C7DT08
names: Similarity
messages: Belongs to the alkaline phosphatase family.

1215089:BBI08 RS04615
gene id: 1215089:BBI08_RS04615
uniprot id: A0A1C7DLM1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

1215089:BBI08 RS13575
gene id: 1215089:BBI08_RS13575
uniprot id: A0A1C7DQW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

1215089:BBI08 RS13540
gene id: 1215089:BBI08_RS13540
uniprot id: A0A1C7DS50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1215089:BBI08 RS08845
gene id: 1215089:BBI08_RS08845
uniprot id: A0A1C7DNH5
names: Similarity
messages: Belongs to the CdaR family.

1215089:BBI08 RS14595
gene id: 1215089:BBI08_RS14595
uniprot id: A0A1C7DRL8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1215089:BBI08 RS05665
gene id: 1215089:BBI08_RS05665
uniprot id: A0A1C7DMH9
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1215089:BBI08 RS04600
gene id: 1215089:BBI08_RS04600
uniprot id: A0A1C7DMF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1215089:BBI08 RS02960
gene id: 1215089:BBI08_RS02960
uniprot id: A0A1C7DUS4
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1215089:BBI08 RS08005
gene id: 1215089:BBI08_RS08005
uniprot id: A0A1C7DNQ5
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1215089:BBI08 RS05170
gene id: 1215089:BBI08_RS05170
uniprot id: A0A1C7DM91
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS09050
gene id: 1215089:BBI08_RS09050
uniprot id: A0A1C7DV51
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS02815
gene id: 1215089:BBI08_RS02815
uniprot id: A0A1C7DVX7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1215089:BBI08 RS01780
gene id: 1215089:BBI08_RS01780
uniprot id: A0A1C7DTL1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

1215089:BBI08 RS04080
gene id: 1215089:BBI08_RS04080
uniprot id: A0A1C7DVT7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS12910
gene id: 1215089:BBI08_RS12910
uniprot id: A0A1C7DR00
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1215089:BBI08 RS15160
gene id: 1215089:BBI08_RS15160
uniprot id: A0A1C7DT22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS15060
gene id: 1215089:BBI08_RS15060
uniprot id: A0A1C7DSD8
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1215089:BBI08 RS00800
gene id: 1215089:BBI08_RS00800
uniprot id: A0A1C7DU23
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1215089:BBI08 RS11935
gene id: 1215089:BBI08_RS11935
uniprot id: A0A1C7DQI1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1215089:BBI08 RS07395
gene id: 1215089:BBI08_RS07395
uniprot id: A0A1C7DN38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1215089:BBI08 RS00360
gene id: 1215089:BBI08_RS00360
uniprot id: A0A1C7DSS7
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1215089:BBI08 RS07745
gene id: 1215089:BBI08_RS07745
uniprot id: A0A1C7DMY1
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1215089:BBI08 RS15270
gene id: 1215089:BBI08_RS15270
uniprot id: A0A1C7DT38
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1215089:BBI08 RS07815
gene id: 1215089:BBI08_RS07815
uniprot id: A0A1C7DNI9
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1215089:BBI08 RS08940
gene id: 1215089:BBI08_RS08940
uniprot id: A0A1C7DP74
names: Cofactor
messages: Binds 1 FAD per subunit.

1215089:BBI08 RS02615
gene id: 1215089:BBI08_RS02615
uniprot id: A0A1C7DUL1
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS10350
gene id: 1215089:BBI08_RS10350
uniprot id: A0A1C7DQF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

1215089:BBI08 RS04765
gene id: 1215089:BBI08_RS04765
uniprot id: A0A1C7DLU4
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1215089:BBI08 RS12120
gene id: 1215089:BBI08_RS12120
uniprot id: A0A1C7DQ80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS02130
gene id: 1215089:BBI08_RS02130
uniprot id: A0A1C7DUD8
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS06425
gene id: 1215089:BBI08_RS06425
uniprot id: A0A1C7DMN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1215089:BBI08 RS05745
gene id: 1215089:BBI08_RS05745
uniprot id: A0A1C7DMG8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1215089:BBI08 RS00610
gene id: 1215089:BBI08_RS00610
uniprot id: A0A1C7DU56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1215089:BBI08 RS10190
gene id: 1215089:BBI08_RS10190
uniprot id: A0A1C7DPS1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1215089:BBI08 RS14685
gene id: 1215089:BBI08_RS14685
uniprot id: A0A1C7DS67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS09250
gene id: 1215089:BBI08_RS09250
uniprot id: A0A1C7DPT0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS01585
gene id: 1215089:BBI08_RS01585
uniprot id: A0A1C7DU35
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS00660
gene id: 1215089:BBI08_RS00660
uniprot id: A0A1C7DU66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1215089:BBI08 RS04495
gene id: 1215089:BBI08_RS04495
uniprot id: A0A1C7DLW3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1215089:BBI08 RS05775
gene id: 1215089:BBI08_RS05775
uniprot id: A0A1C7DMJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS05160
gene id: 1215089:BBI08_RS05160
uniprot id: A0A1C7DLV6
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS16330
gene id: 1215089:BBI08_RS16330
uniprot id: A0A1C7DSR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

1215089:BBI08 RS11120
gene id: 1215089:BBI08_RS11120
uniprot id: A0A1C7DPP6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1215089:BBI08 RS13945
gene id: 1215089:BBI08_RS13945
uniprot id: A0A1C7DRS7
names: Caution
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1215089:BBI08 RS10950
gene id: 1215089:BBI08_RS10950
uniprot id: A0A1C7DPV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1215089:BBI08 RS14210
gene id: 1215089:BBI08_RS14210
uniprot id: A0A1C7DRX4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

1215089:BBI08 RS03650
gene id: 1215089:BBI08_RS03650
uniprot id: A0A1C7DUK8
names: Function
names: Similarity
messages: Functions as a fatty acid monooxygenase.
messages: In the N-terminal section; belongs to the cytochrome P450 family.

1215089:BBI08 RS07040
gene id: 1215089:BBI08_RS07040
uniprot id: A0A1C7DMT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1215089:BBI08 RS02595
gene id: 1215089:BBI08_RS02595
uniprot id: A0A1C7DTX8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS08900
gene id: 1215089:BBI08_RS08900
uniprot id: A0A1C7DNI5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS05405
gene id: 1215089:BBI08_RS05405
uniprot id: A0A1C7DMT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1215089:BBI08 RS15395
gene id: 1215089:BBI08_RS15395
uniprot id: A0A1C7DSK8
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

1215089:BBI08 RS15515
gene id: 1215089:BBI08_RS15515
uniprot id: A0A1C7DT03
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS14080
gene id: 1215089:BBI08_RS14080
uniprot id: A0A1C7DS07
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1215089:BBI08 RS11005
gene id: 1215089:BBI08_RS11005
uniprot id: A0A1C7DQ50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1215089:BBI08 RS03955
gene id: 1215089:BBI08_RS03955
uniprot id: A0A1C7DV11
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS11895
gene id: 1215089:BBI08_RS11895
uniprot id: A0A1C7DQM8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. SigI subfamily.
messages: Cytoplasm
messages: Interacts with RsgI.
messages: Negatively regulated by the anti-sigma-I factor RsgI.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1215089:BBI08 RS02235
gene id: 1215089:BBI08_RS02235
uniprot id: A0A1C7DUZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS12965
gene id: 1215089:BBI08_RS12965
uniprot id: A0A1C7DQW3
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1215089:BBI08 RS16160
gene id: 1215089:BBI08_RS16160
uniprot id: A0A1C7DTK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1215089:BBI08 RS03620
gene id: 1215089:BBI08_RS03620
uniprot id: A0A1C7DVN4
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1215089:BBI08 RS12250
gene id: 1215089:BBI08_RS12250
uniprot id: A0A1C7DQU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

1215089:BBI08 RS08850
gene id: 1215089:BBI08_RS08850
uniprot id: A0A1C7DPE5
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1215089:BBI08 RS13545
gene id: 1215089:BBI08_RS13545
uniprot id: A0A1C7DRJ7
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS10810
gene id: 1215089:BBI08_RS10810
uniprot id: A0A1C7DPG9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1215089:BBI08 RS12470
gene id: 1215089:BBI08_RS12470
uniprot id: A0A1C7DVQ3
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS09890
gene id: 1215089:BBI08_RS09890
uniprot id: A0A1C7DPE1
names: Similarity
messages: Belongs to the creatininase superfamily.

1215089:BBI08 RS06065
gene id: 1215089:BBI08_RS06065
uniprot id: A0A1C7DMY8
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1215089:BBI08 RS15245
gene id: 1215089:BBI08_RS15245
uniprot id: A0A1C7DSN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.
messages: Homotetramer.

1215089:BBI08 RS12885
gene id: 1215089:BBI08_RS12885
uniprot id: A0A1C7DQJ6
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

1215089:BBI08 RS14565
gene id: 1215089:BBI08_RS14565
uniprot id: A0A1C7DSQ7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1215089:BBI08 RS02340
gene id: 1215089:BBI08_RS02340
uniprot id: A0A1C7DUH8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1215089:BBI08 RS01380
gene id: 1215089:BBI08_RS01380
uniprot id: A0A1C7DUK0
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS12830
gene id: 1215089:BBI08_RS12830
uniprot id: A0A1C7DQL3
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS00275
gene id: 1215089:BBI08_RS00275
uniprot id: A0A1C7DT93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1215089:BBI08 RS06750
gene id: 1215089:BBI08_RS06750
uniprot id: A0A1C7DNB5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1215089:BBI08 RS16810
gene id: 1215089:BBI08_RS16810
uniprot id: A0A1C7DTP2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1215089:BBI08 RS07920
gene id: 1215089:BBI08_RS07920
uniprot id: A0A1C7DNX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1215089:BBI08 RS13855
gene id: 1215089:BBI08_RS13855
uniprot id: A0A1C7DRI4
names: Similarity
messages: Belongs to the ThiD family.

1215089:BBI08 RS16685
gene id: 1215089:BBI08_RS16685
uniprot id: A0A1C7DTG1
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS07355
gene id: 1215089:BBI08_RS07355
uniprot id: A0A1C7DN65
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1215089:BBI08 RS07870
gene id: 1215089:BBI08_RS07870
uniprot id: A0A1C7DNJ8
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1215089:BBI08 RS11640
gene id: 1215089:BBI08_RS11640
uniprot id: A0A1C7DQH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1215089:BBI08 RS05025
gene id: 1215089:BBI08_RS05025
uniprot id: A0A1C7DMG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1215089:BBI08 RS11890
gene id: 1215089:BBI08_RS11890
uniprot id: A0A1C7DQC0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS12525
gene id: 1215089:BBI08_RS12525
uniprot id: A0A1C7DRL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS16145
gene id: 1215089:BBI08_RS16145
uniprot id: A0A1C7DS92
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS06655
gene id: 1215089:BBI08_RS06655
uniprot id: A0A1C7DMW4
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1215089:BBI08 RS00790
gene id: 1215089:BBI08_RS00790
uniprot id: A0A1C7DT41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1215089:BBI08 RS04945
gene id: 1215089:BBI08_RS04945
uniprot id: A0A1C7DVI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm

1215089:BBI08 RS05785
gene id: 1215089:BBI08_RS05785
uniprot id: A0A1C7DLZ3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS09355
gene id: 1215089:BBI08_RS09355
uniprot id: A0A1C7DPA2
names: Similarity
messages: Belongs to the peptidase S66 family.

1215089:BBI08 RS06920
gene id: 1215089:BBI08_RS06920
uniprot id: A0A1C7DNJ4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1215089:BBI08 RS08455
gene id: 1215089:BBI08_RS08455
uniprot id: A0A1C7DNT6
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1215089:BBI08 RS07120
gene id: 1215089:BBI08_RS07120
uniprot id: A0A1C7DN58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1215089:BBI08 RS05730
gene id: 1215089:BBI08_RS05730
uniprot id: A0A1C7DLX7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1215089:BBI08 RS10380
gene id: 1215089:BBI08_RS10380
uniprot id: A0A1C7DPC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1215089:BBI08 RS06595
gene id: 1215089:BBI08_RS06595
uniprot id: A0A1C7DMB0
names: Similarity
messages: Belongs to the citrate synthase family.

1215089:BBI08 RS00280
gene id: 1215089:BBI08_RS00280
uniprot id: A0A1C7DVC5
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS07540
gene id: 1215089:BBI08_RS07540
uniprot id: A0A1C7DNW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS05070
gene id: 1215089:BBI08_RS05070
uniprot id: A0A1C7DM70
names: Similarity
messages: Belongs to the UPF0342 family.

1215089:BBI08 RS03740
gene id: 1215089:BBI08_RS03740
uniprot id: A0A1C7DV74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS11155
gene id: 1215089:BBI08_RS11155
uniprot id: A0A1C7DQ36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1215089:BBI08 RS10100
gene id: 1215089:BBI08_RS10100
uniprot id: A0A1C7DPF9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1215089:BBI08 RS13980
gene id: 1215089:BBI08_RS13980
uniprot id: A0A1C7DR87
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1215089:BBI08 RS00345
gene id: 1215089:BBI08_RS00345
uniprot id: A0A1C7DTG2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1215089:BBI08 RS11320
gene id: 1215089:BBI08_RS11320
uniprot id: A0A1C7DQ25
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
messages: Cytoplasm
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.

1215089:BBI08 RS11105
gene id: 1215089:BBI08_RS11105
uniprot id: A0A1C7DPY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1215089:BBI08 RS01015
gene id: 1215089:BBI08_RS01015
uniprot id: A0A1C7DTT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1215089:BBI08 RS00545
gene id: 1215089:BBI08_RS00545
uniprot id: A0A1C7DSU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1215089:BBI08 RS16640
gene id: 1215089:BBI08_RS16640
uniprot id: A0A1C7DTL8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1215089:BBI08 RS05825
gene id: 1215089:BBI08_RS05825
uniprot id: A0A1C7DML0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family. RocA subfamily.

1215089:BBI08 RS08865
gene id: 1215089:BBI08_RS08865
uniprot id: A0A1C7DP25
names: Similarity
messages: Belongs to the citrate synthase family.

1215089:BBI08 RS06865
gene id: 1215089:BBI08_RS06865
uniprot id: A0A1C7DN12
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1215089:BBI08 RS01695
gene id: 1215089:BBI08_RS01695
uniprot id: A0A1C7DUN8
names: Similarity
messages: Belongs to the SCO1/2 family.

1215089:BBI08 RS06980
gene id: 1215089:BBI08_RS06980
uniprot id: A0A1C7DN33
names: Subcellular Location Annotation
messages: Cell membrane

1215089:BBI08 RS10845
gene id: 1215089:BBI08_RS10845
uniprot id: A0A1C7DQ26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1215089:BBI08 RS13490
gene id: 1215089:BBI08_RS13490
uniprot id: A0A1C7DS41
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS14935
gene id: 1215089:BBI08_RS14935
uniprot id: A0A1C7DRM0
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1215089:BBI08 RS02635
gene id: 1215089:BBI08_RS02635
uniprot id: A0A1C7DUM3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1215089:BBI08 RS06680
gene id: 1215089:BBI08_RS06680
uniprot id: A0A1C7DMT7
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS12135
gene id: 1215089:BBI08_RS12135
uniprot id: A0A1C7DQV6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1215089:BBI08 RS12055
gene id: 1215089:BBI08_RS12055
uniprot id: A0A1C7DQT2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

1215089:BBI08 RS06715
gene id: 1215089:BBI08_RS06715
uniprot id: A0A1C7DMX6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1215089:BBI08 RS06230
gene id: 1215089:BBI08_RS06230
uniprot id: A0A1C7DM47
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS01175
gene id: 1215089:BBI08_RS01175
uniprot id: A0A1C7DTV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1215089:BBI08 RS02890
gene id: 1215089:BBI08_RS02890
uniprot id: A0A1C7DV98
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1215089:BBI08 RS15615
gene id: 1215089:BBI08_RS15615
uniprot id: A0A1C7DRZ4
names: Similarity
messages: Belongs to the Gfa family.

1215089:BBI08 RS15820
gene id: 1215089:BBI08_RS15820
uniprot id: A0A1C7DSZ7
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

1215089:BBI08 RS06035
gene id: 1215089:BBI08_RS06035
uniprot id: A0A1C7DMD5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1215089:BBI08 RS02385
gene id: 1215089:BBI08_RS02385
uniprot id: A0A1C7DTY1
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1215089:BBI08 RS15600
gene id: 1215089:BBI08_RS15600
uniprot id: A0A1C7DSP2
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS12220
gene id: 1215089:BBI08_RS12220
uniprot id: A0A1C7DR06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1215089:BBI08 RS00785
gene id: 1215089:BBI08_RS00785
uniprot id: A0A1C7DTX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1215089:BBI08 RS11885
gene id: 1215089:BBI08_RS11885
uniprot id: A0A1C7DQH3
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS09220
gene id: 1215089:BBI08_RS09220
uniprot id: A0A1C7DP77
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1215089:BBI08 RS04670
gene id: 1215089:BBI08_RS04670
uniprot id: A0A1C7DLN2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1215089:BBI08 RS00260
gene id: 1215089:BBI08_RS00260
uniprot id: A0A1C7DTF9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1215089:BBI08 RS05635
gene id: 1215089:BBI08_RS05635
uniprot id: A0A1C7DMF0
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1215089:BBI08 RS08015
gene id: 1215089:BBI08_RS08015
uniprot id: A0A1C7DN30
names: Similarity
messages: Belongs to the HesB/IscA family.

1215089:BBI08 RS04630
gene id: 1215089:BBI08_RS04630
uniprot id: A0A1C7DM13
names: Similarity
messages: Belongs to the UPF0435 family.

1215089:BBI08 RS00625
gene id: 1215089:BBI08_RS00625
uniprot id: A0A1C7DT92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1215089:BBI08 RS00680
gene id: 1215089:BBI08_RS00680
uniprot id: A0A1C7DTL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1215089:BBI08 RS08475
gene id: 1215089:BBI08_RS08475
uniprot id: A0A1C7DP72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS12690
gene id: 1215089:BBI08_RS12690
uniprot id: A0A1C7DR27
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1215089:BBI08 RS07380
gene id: 1215089:BBI08_RS07380
uniprot id: A0A1C7DNA4
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1215089:BBI08 RS07575
gene id: 1215089:BBI08_RS07575
uniprot id: A0A1C7DMU7
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1215089:BBI08 RS13335
gene id: 1215089:BBI08_RS13335
uniprot id: A0A1C7DS10
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1215089:BBI08 RS04280
gene id: 1215089:BBI08_RS04280
uniprot id: A0A1C7DVI2
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1215089:BBI08 RS06410
gene id: 1215089:BBI08_RS06410
uniprot id: A0A1C7DMR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1215089:BBI08 RS02475
gene id: 1215089:BBI08_RS02475
uniprot id: A0A1C7DU92
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Central regulator of manganese homeostasis.
messages: Cytoplasm
messages: DNA binding is strongly activated by Mn(2+).
messages: Homodimer.

1215089:BBI08 RS02440
gene id: 1215089:BBI08_RS02440
uniprot id: A0A1C7DTU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1215089:BBI08 RS11075
gene id: 1215089:BBI08_RS11075
uniprot id: A0A1C7DQM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1215089:BBI08 RS04415
gene id: 1215089:BBI08_RS04415
uniprot id: A0A1C7DLS6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1215089:BBI08 RS06685
gene id: 1215089:BBI08_RS06685
uniprot id: A0A1C7DN00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1215089:BBI08 RS14240
gene id: 1215089:BBI08_RS14240
uniprot id: A0A1C7DR90
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Consists of two distinct domains; an N-terminal heme-containing oxygen-binding domain and a C-terminal reductase domain with binding sites for FAD and NAD(P)H.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS07550
gene id: 1215089:BBI08_RS07550
uniprot id: A0A1C7DN70
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

1215089:BBI08 RS13925
gene id: 1215089:BBI08_RS13925
uniprot id: A0A1C7DRY0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1215089:BBI08 RS12325
gene id: 1215089:BBI08_RS12325
uniprot id: A0A1C7DQK0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system DegS/DegU, which plays an important role in the transition growth phase.

1215089:BBI08 RS15370
gene id: 1215089:BBI08_RS15370
uniprot id: A0A1C7DSJ9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1215089:BBI08 RS00570
gene id: 1215089:BBI08_RS00570
uniprot id: A0A1C7DTD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1215089:BBI08 RS16345
gene id: 1215089:BBI08_RS16345
uniprot id: A0A1C7DSI0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1215089:BBI08 RS14100
gene id: 1215089:BBI08_RS14100
uniprot id: A0A1C7DRW0
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1215089:BBI08 RS11180
gene id: 1215089:BBI08_RS11180
uniprot id: A0A1C7DPN4
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1215089:BBI08 RS13225
gene id: 1215089:BBI08_RS13225
uniprot id: A0A1C7DRP4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1215089:BBI08 RS13685
gene id: 1215089:BBI08_RS13685
uniprot id: A0A1C7DRN4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1215089:BBI08 RS06050
gene id: 1215089:BBI08_RS06050
uniprot id: A0A1C7DMN1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1215089:BBI08 RS07500
gene id: 1215089:BBI08_RS07500
uniprot id: A0A1C7DN59
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1215089:BBI08 RS14550
gene id: 1215089:BBI08_RS14550
uniprot id: A0A1C7DRE6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1215089:BBI08 RS02600
gene id: 1215089:BBI08_RS02600
uniprot id: A0A1C7DV01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1215089:BBI08 RS16590
gene id: 1215089:BBI08_RS16590
uniprot id: A0A1C7DT70
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1215089:BBI08 RS07060
gene id: 1215089:BBI08_RS07060
uniprot id: A0A1C7DMK4
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

1215089:BBI08 RS11265
gene id: 1215089:BBI08_RS11265
uniprot id: A0A1C7DQA6
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

1215089:BBI08 RS00125
gene id: 1215089:BBI08_RS00125
uniprot id: A0A1C7DSN6
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1215089:BBI08 RS09245
gene id: 1215089:BBI08_RS09245
uniprot id: A0A1C7DP83
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1215089:BBI08 RS02825
gene id: 1215089:BBI08_RS02825
uniprot id: A0A1C7DU08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1215089:BBI08 RS02265
gene id: 1215089:BBI08_RS02265
uniprot id: A0A1C7DTW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1215089:BBI08 RS04405
gene id: 1215089:BBI08_RS04405
uniprot id: A0A1C7DLN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1215089:BBI08 RS07435
gene id: 1215089:BBI08_RS07435
uniprot id: A0A1C7DNB4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1215089:BBI08 RS08080
gene id: 1215089:BBI08_RS08080
uniprot id: A0A1C7DNN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1215089:BBI08 RS07760
gene id: 1215089:BBI08_RS07760
uniprot id: A0A1C7DP02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1215089:BBI08 RS14600
gene id: 1215089:BBI08_RS14600
uniprot id: A0A1C7DRF6
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

1215089:BBI08 RS12530
gene id: 1215089:BBI08_RS12530
uniprot id: A0A1C7DQZ6
names: Subcellular Location Annotation
messages: Cell membrane

1215089:BBI08 RS09160
gene id: 1215089:BBI08_RS09160
uniprot id: A0A1C7DP06
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Forms a 24-polypeptide structural core with octahedral symmetry. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

1215089:BBI08 RS10430
gene id: 1215089:BBI08_RS10430
uniprot id: A0A1C7DPD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0154 family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS13170
gene id: 1215089:BBI08_RS13170
uniprot id: A0A1C7DRD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1215089:BBI08 RS07520
gene id: 1215089:BBI08_RS07520
uniprot id: A0A1C7DMV6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1215089:BBI08 RS04025
gene id: 1215089:BBI08_RS04025
uniprot id: A0A1C7DUP3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS15180
gene id: 1215089:BBI08_RS15180
uniprot id: A0A1C7DS52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS12415
gene id: 1215089:BBI08_RS12415
uniprot id: A0A1C7DQX4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

1215089:BBI08 RS05620
gene id: 1215089:BBI08_RS05620
uniprot id: A0A1C7DLV7
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1215089:BBI08 RS08465
gene id: 1215089:BBI08_RS08465
uniprot id: A0A1C7DNB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS11085
gene id: 1215089:BBI08_RS11085
uniprot id: A0A1C7DUZ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1215089:BBI08 RS03660
gene id: 1215089:BBI08_RS03660
uniprot id: A0A1C7DVJ4
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the L-aspartate dehydrogenase family.
messages: Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
messages: The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia.

1215089:BBI08 RS00365
gene id: 1215089:BBI08_RS00365
uniprot id: A0A1C7DTV2
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1215089:BBI08 RS00195
gene id: 1215089:BBI08_RS00195
uniprot id: A0A1C7DSU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1215089:BBI08 RS07110
gene id: 1215089:BBI08_RS07110
uniprot id: A0A1C7DMK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1215089:BBI08 RS06745
gene id: 1215089:BBI08_RS06745
uniprot id: A0A1C7DME0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1215089:BBI08 RS11450
gene id: 1215089:BBI08_RS11450
uniprot id: A0A1C7DPT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1215089:BBI08 RS11200
gene id: 1215089:BBI08_RS11200
uniprot id: A0A1C7DQB2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1215089:BBI08 RS08670
gene id: 1215089:BBI08_RS08670
uniprot id: A0A1C7DNN7
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

1215089:BBI08 RS14960
gene id: 1215089:BBI08_RS14960
uniprot id: A0A1C7DS57
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1215089:BBI08 RS12450
gene id: 1215089:BBI08_RS12450
uniprot id: A0A1C7DQB7
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

1215089:BBI08 RS00145
gene id: 1215089:BBI08_RS00145
uniprot id: A0A1C7DTR2
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1215089:BBI08 RS07150
gene id: 1215089:BBI08_RS07150
uniprot id: A0A1C7DN89
names: Similarity
messages: Belongs to the RecJ family.

1215089:BBI08 RS10255
gene id: 1215089:BBI08_RS10255
uniprot id: A0A1C7DPT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease PrsW family.
messages: Cell membrane
messages: Involved in the degradation of specific anti-sigma factors.
messages: Membrane

1215089:BBI08 RS06755
gene id: 1215089:BBI08_RS06755
uniprot id: A0A1C7DMY4
names: Function
messages: Required for transformation and DNA binding.

1215089:BBI08 RS04740
gene id: 1215089:BBI08_RS04740
uniprot id: A0A1C7DLI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS02380
gene id: 1215089:BBI08_RS02380
uniprot id: A0A1C7DUR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1215089:BBI08 RS12240
gene id: 1215089:BBI08_RS12240
uniprot id: A0A1C7DQX5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1215089:BBI08 RS10035
gene id: 1215089:BBI08_RS10035
uniprot id: A0A1C7DQ85
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1215089:BBI08 RS14875
gene id: 1215089:BBI08_RS14875
uniprot id: A0A1C7DSF7
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS11915
gene id: 1215089:BBI08_RS11915
uniprot id: A0A1C7DR19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1215089:BBI08 RS00075
gene id: 1215089:BBI08_RS00075
uniprot id: A0A1C7DTX6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS00265
gene id: 1215089:BBI08_RS00265
uniprot id: A0A1C7DU07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1215089:BBI08 RS06890
gene id: 1215089:BBI08_RS06890
uniprot id: A0A1C7DMX4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1215089:BBI08 RS11335
gene id: 1215089:BBI08_RS11335
uniprot id: A0A1C7DPT1
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1215089:BBI08 RS16240
gene id: 1215089:BBI08_RS16240
uniprot id: A0A1C7DT76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1215089:BBI08 RS00895
gene id: 1215089:BBI08_RS00895
uniprot id: A0A1C7DT05
names: Similarity
messages: Belongs to the citrate synthase family.

1215089:BBI08 RS04965
gene id: 1215089:BBI08_RS04965
uniprot id: A0A1C7DLK1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1215089:BBI08 RS03160
gene id: 1215089:BBI08_RS03160
uniprot id: A0A1C7DUW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS11925
gene id: 1215089:BBI08_RS11925
uniprot id: A0A1C7DRA1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1215089:BBI08 RS14850
gene id: 1215089:BBI08_RS14850
uniprot id: A0A1C7DSV6
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS00520
gene id: 1215089:BBI08_RS00520
uniprot id: A0A1C7DTC1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1215089:BBI08 RS05330
gene id: 1215089:BBI08_RS05330
uniprot id: A0A1C7DLQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1215089:BBI08 RS01255
gene id: 1215089:BBI08_RS01255
uniprot id: A0A1C7DTC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS13825
gene id: 1215089:BBI08_RS13825
uniprot id: A0A1C7DR59
names: Similarity
messages: Belongs to the ChdC family. Type 1 subfamily.

1215089:BBI08 RS06695
gene id: 1215089:BBI08_RS06695
uniprot id: A0A1C7DMC9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1215089:BBI08 RS13560
gene id: 1215089:BBI08_RS13560
uniprot id: A0A1C7DRL2
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1215089:BBI08 RS07770
gene id: 1215089:BBI08_RS07770
uniprot id: A0A1C7DW08
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1215089:BBI08 RS00690
gene id: 1215089:BBI08_RS00690
uniprot id: A0A1C7DT17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1215089:BBI08 RS14380
gene id: 1215089:BBI08_RS14380
uniprot id: A0A1C7DS16
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS08785
gene id: 1215089:BBI08_RS08785
uniprot id: A0A1C7DP47
names: Function
names: Similarity
messages: Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.

1215089:BBI08 RS00160
gene id: 1215089:BBI08_RS00160
uniprot id: A0A1C7DTY7
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1215089:BBI08 RS12555
gene id: 1215089:BBI08_RS12555
uniprot id: A0A1C7DQG2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1215089:BBI08 RS16165
gene id: 1215089:BBI08_RS16165
uniprot id: A0A1C7DSZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1215089:BBI08 RS04975
gene id: 1215089:BBI08_RS04975
uniprot id: A0A1C7DM28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family. BdbC subfamily.
messages: Membrane

1215089:BBI08 RS14795
gene id: 1215089:BBI08_RS14795
uniprot id: A0A1C7DS84
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1215089:BBI08 RS00620
gene id: 1215089:BBI08_RS00620
uniprot id: A0A1C7DTE1
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1215089:BBI08 RS15275
gene id: 1215089:BBI08_RS15275
uniprot id: A0A1C7DSI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS03870
gene id: 1215089:BBI08_RS03870
uniprot id: A0A1C7DUK7
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1215089:BBI08 RS14995
gene id: 1215089:BBI08_RS14995
uniprot id: A0A1C7DSN1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1215089:BBI08 RS02435
gene id: 1215089:BBI08_RS02435
uniprot id: A0A1C7DTZ1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1215089:BBI08 RS14920
gene id: 1215089:BBI08_RS14920
uniprot id: A0A1C7DSB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS05845
gene id: 1215089:BBI08_RS05845
uniprot id: A0A1C7DMJ5
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS14590
gene id: 1215089:BBI08_RS14590
uniprot id: A0A1C7DSA8
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1215089:BBI08 RS13730
gene id: 1215089:BBI08_RS13730
uniprot id: A0A1C7DRZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1215089:BBI08 RS08665
gene id: 1215089:BBI08_RS08665
uniprot id: A0A1C7DNS7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1215089:BBI08 RS10805
gene id: 1215089:BBI08_RS10805
uniprot id: A0A1C7DPI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1215089:BBI08 RS12480
gene id: 1215089:BBI08_RS12480
uniprot id: A0A1C7DQS2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS06470
gene id: 1215089:BBI08_RS06470
uniprot id: A0A1C7DMH3
names: Similarity
messages: Belongs to the peptidase S49 family.

1215089:BBI08 RS03780
gene id: 1215089:BBI08_RS03780
uniprot id: A0A1C7DV77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:citrate (SCF) symporter family.
messages: Cell membrane

1215089:BBI08 RS06290
gene id: 1215089:BBI08_RS06290
uniprot id: A0A1C7DMQ3
names: Function
names: Similarity
names: Subunit
messages: Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha-keto acid in the first half-reaction.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1215089:BBI08 RS07680
gene id: 1215089:BBI08_RS07680
uniprot id: A0A1C7DMX0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

1215089:BBI08 RS11375
gene id: 1215089:BBI08_RS11375
uniprot id: A0A1C7DQ32
names: Subcellular Location Annotation
messages: Cytoplasm

1215089:BBI08 RS01720
gene id: 1215089:BBI08_RS01720
uniprot id: A0A1C7DUF6
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1215089:BBI08 RS06000
gene id: 1215089:BBI08_RS06000
uniprot id: A0A1C7DM07
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS11100
gene id: 1215089:BBI08_RS11100
uniprot id: A0A1C7DQ28
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1215089:BBI08 RS05280
gene id: 1215089:BBI08_RS05280
uniprot id: A0A1C7DLQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1215089:BBI08 RS10930
gene id: 1215089:BBI08_RS10930
uniprot id: A0A1C7DQ58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1215089:BBI08 RS14780
gene id: 1215089:BBI08_RS14780
uniprot id: A0A1C7DRI5
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1215089:BBI08 RS06690
gene id: 1215089:BBI08_RS06690
uniprot id: A0A1C7DMD6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1215089:BBI08 RS09075
gene id: 1215089:BBI08_RS09075
uniprot id: A0A1C7DP95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1215089:BBI08 RS04490
gene id: 1215089:BBI08_RS04490
uniprot id: A0A1C7DM90
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1215089:BBI08 RS07885
gene id: 1215089:BBI08_RS07885
uniprot id: A0A1C7DND2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1215089:BBI08 RS04185
gene id: 1215089:BBI08_RS04185
uniprot id: A0A1C7DVG3
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1215089:BBI08 RS15035
gene id: 1215089:BBI08_RS15035
uniprot id: A0A1C7DRU6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS00675
gene id: 1215089:BBI08_RS00675
uniprot id: A0A1C7DTA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1215089:BBI08 RS01975
gene id: 1215089:BBI08_RS01975
uniprot id: A0A1C7DUA1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1215089:BBI08 RS17215
gene id: 1215089:BBI08_RS17215
uniprot id: A0A1C7DSQ6
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS06475
gene id: 1215089:BBI08_RS06475
uniprot id: A0A1C7DMQ2
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS11130
gene id: 1215089:BBI08_RS11130
uniprot id: A0A1C7DW45
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

1215089:BBI08 RS00590
gene id: 1215089:BBI08_RS00590
uniprot id: A0A1C7DT04
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

1215089:BBI08 RS11750
gene id: 1215089:BBI08_RS11750
uniprot id: A0A1C7DQR9
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS00615
gene id: 1215089:BBI08_RS00615
uniprot id: A0A1C7DTK6
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1215089:BBI08 RS05835
gene id: 1215089:BBI08_RS05835
uniprot id: A0A1C7DM02
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1215089:BBI08 RS07170
gene id: 1215089:BBI08_RS07170
uniprot id: A0A1C7DN72
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1215089:BBI08 RS10995
gene id: 1215089:BBI08_RS10995
uniprot id: A0A1C7DQ03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1215089:BBI08 RS16365
gene id: 1215089:BBI08_RS16365
uniprot id: A0A1C7DTP1
names: Similarity
messages: Belongs to the IlvD/Edd family.

1215089:BBI08 RS02110
gene id: 1215089:BBI08_RS02110
uniprot id: A0A1C7DUM4
names: Subcellular Location Annotation
messages: Cytoplasm

1215089:BBI08 RS15520
gene id: 1215089:BBI08_RS15520
uniprot id: A0A1C7DSM9
names: Similarity
messages: Belongs to the DDAH family.

1215089:BBI08 RS09515
gene id: 1215089:BBI08_RS09515
uniprot id: A0A1C7DPR0
names: Function
names: Similarity
names: Subunit
messages: In the N-terminal section; belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily.
messages: Monomer.
messages: Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine.

1215089:BBI08 RS09120
gene id: 1215089:BBI08_RS09120
uniprot id: A0A1C7DP57
names: Subcellular Location Annotation
messages: Cytoplasm

1215089:BBI08 RS05305
gene id: 1215089:BBI08_RS05305
uniprot id: A0A1C7DM24
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1215089:BBI08 RS00710
gene id: 1215089:BBI08_RS00710
uniprot id: A0A1C7DU76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1215089:BBI08 RS04240
gene id: 1215089:BBI08_RS04240
uniprot id: A0A1C7DVW7
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

1215089:BBI08 RS07360
gene id: 1215089:BBI08_RS07360
uniprot id: A0A1C7DND3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1215089:BBI08 RS11325
gene id: 1215089:BBI08_RS11325
uniprot id: A0A1C7DQB6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

1215089:BBI08 RS07265
gene id: 1215089:BBI08_RS07265
uniprot id: A0A1C7DMQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

1215089:BBI08 RS15435
gene id: 1215089:BBI08_RS15435
uniprot id: A0A1C7DSE8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS12465
gene id: 1215089:BBI08_RS12465
uniprot id: A0A1C7DRJ9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1215089:BBI08 RS01815
gene id: 1215089:BBI08_RS01815
uniprot id: A0A1C7DU71
names: Similarity
messages: Belongs to the UPF0398 family.

1215089:BBI08 RS09080
gene id: 1215089:BBI08_RS09080
uniprot id: A0A1C7DNN2
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1215089:BBI08 RS02335
gene id: 1215089:BBI08_RS02335
uniprot id: A0A1C7DUV0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1215089:BBI08 RS05995
gene id: 1215089:BBI08_RS05995
uniprot id: A0A1C7DM08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MenH family.
messages: Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
messages: Monomer.

1215089:BBI08 RS07595
gene id: 1215089:BBI08_RS07595
uniprot id: A0A1C7DNF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS02345
gene id: 1215089:BBI08_RS02345
uniprot id: A0A1C7DVT1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1215089:BBI08 RS14200
gene id: 1215089:BBI08_RS14200
uniprot id: A0A1C7DRX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1215089:BBI08 RS15410
gene id: 1215089:BBI08_RS15410
uniprot id: A0A1C7DRV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1215089:BBI08 RS04430
gene id: 1215089:BBI08_RS04430
uniprot id: A0A1C7DLC2
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1215089:BBI08 RS00915
gene id: 1215089:BBI08_RS00915
uniprot id: A0A1C7DTQ4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1215089:BBI08 RS02285
gene id: 1215089:BBI08_RS02285
uniprot id: A0A1C7DV02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS10385
gene id: 1215089:BBI08_RS10385
uniprot id: A0A1C7DPA1
names: Similarity
messages: Belongs to the Fur family.

1215089:BBI08 RS09135
gene id: 1215089:BBI08_RS09135
uniprot id: A0A1C7DNM2
names: Similarity
messages: Belongs to the TelA family.

1215089:BBI08 RS01965
gene id: 1215089:BBI08_RS01965
uniprot id: A0A1C7DUA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS04450
gene id: 1215089:BBI08_RS04450
uniprot id: A0A1C7DMC3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

1215089:BBI08 RS00715
gene id: 1215089:BBI08_RS00715
uniprot id: A0A1C7DTM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1215089:BBI08 RS00020
gene id: 1215089:BBI08_RS00020
uniprot id: A0A1C7DT52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1215089:BBI08 RS02250
gene id: 1215089:BBI08_RS02250
uniprot id: A0A1C7DU53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1215089:BBI08 RS12125
gene id: 1215089:BBI08_RS12125
uniprot id: A0A1C7DQ51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS12900
gene id: 1215089:BBI08_RS12900
uniprot id: A0A1C7DRT2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1215089:BBI08 RS02465
gene id: 1215089:BBI08_RS02465
uniprot id: A0A1C7DUI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1215089:BBI08 RS07565
gene id: 1215089:BBI08_RS07565
uniprot id: A0A1C7DNH3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS13735
gene id: 1215089:BBI08_RS13735
uniprot id: A0A1C7DRP3
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

1215089:BBI08 RS04435
gene id: 1215089:BBI08_RS04435
uniprot id: A0A1C7DLC9
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1215089:BBI08 RS14440
gene id: 1215089:BBI08_RS14440
uniprot id: A0A1C7DRI9
names: Similarity
messages: Belongs to the peptidase S13 family.

1215089:BBI08 RS12080
gene id: 1215089:BBI08_RS12080
uniprot id: A0A1C7DR48
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1215089:BBI08 RS02810
gene id: 1215089:BBI08_RS02810
uniprot id: A0A1C7DUP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

1215089:BBI08 RS13660
gene id: 1215089:BBI08_RS13660
uniprot id: A0A1C7DRN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RpoE family.
messages: Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunits. The core is associated with a delta subunit and one of several sigma factors.

1215089:BBI08 RS02415
gene id: 1215089:BBI08_RS02415
uniprot id: A0A1C7DUA8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1215089:BBI08 RS07190
gene id: 1215089:BBI08_RS07190
uniprot id: A0A1C7DMW9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS00935
gene id: 1215089:BBI08_RS00935
uniprot id: A0A1C7DTZ4
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1215089:BBI08 RS13985
gene id: 1215089:BBI08_RS13985
uniprot id: A0A1C7DR41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1215089:BBI08 RS12800
gene id: 1215089:BBI08_RS12800
uniprot id: A0A1C7DRQ9
names: Similarity
messages: Belongs to the YciI family.

1215089:BBI08 RS15655
gene id: 1215089:BBI08_RS15655
uniprot id: A0A1C7DSQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family. NanA subfamily.
messages: Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate.
messages: Cytoplasm
messages: Homotetramer.

1215089:BBI08 RS06005
gene id: 1215089:BBI08_RS06005
uniprot id: A0A1C7DVJ6
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.
messages: Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA).

1215089:BBI08 RS10175
gene id: 1215089:BBI08_RS10175
uniprot id: A0A1C7DQ47
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1215089:BBI08 RS12790
gene id: 1215089:BBI08_RS12790
uniprot id: A0A1C7DRG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1215089:BBI08 RS00310
gene id: 1215089:BBI08_RS00310
uniprot id: A0A1C7DTU2
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1215089:BBI08 RS11505
gene id: 1215089:BBI08_RS11505
uniprot id: A0A1C7DQU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm

1215089:BBI08 RS02830
gene id: 1215089:BBI08_RS02830
uniprot id: A0A1C7DV37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1215089:BBI08 RS04505
gene id: 1215089:BBI08_RS04505
uniprot id: A0A1C7DLW1
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1215089:BBI08 RS16605
gene id: 1215089:BBI08_RS16605
uniprot id: A0A1C7DT07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS13180
gene id: 1215089:BBI08_RS13180
uniprot id: A0A1C7DRC3
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS06795
gene id: 1215089:BBI08_RS06795
uniprot id: A0A1C7DMF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

1215089:BBI08 RS14480
gene id: 1215089:BBI08_RS14480
uniprot id: A0A1C7DS32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1215089:BBI08 RS14465
gene id: 1215089:BBI08_RS14465
uniprot id: A0A1C7DS27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

1215089:BBI08 RS15580
gene id: 1215089:BBI08_RS15580
uniprot id: A0A1C7DT98
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS08225
gene id: 1215089:BBI08_RS08225
uniprot id: A0A1C7DNP2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS02310
gene id: 1215089:BBI08_RS02310
uniprot id: A0A1C7DUR0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS12520
gene id: 1215089:BBI08_RS12520
uniprot id: A0A1C7DR22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS04160
gene id: 1215089:BBI08_RS04160
uniprot id: A0A1C7DVF7
names: Similarity
messages: Belongs to the CdaR family.

1215089:BBI08 RS02925
gene id: 1215089:BBI08_RS02925
uniprot id: A0A1C7DU33
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS11825
gene id: 1215089:BBI08_RS11825
uniprot id: A0A1C7DR82
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS16050
gene id: 1215089:BBI08_RS16050
uniprot id: A0A1C7DSX3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1215089:BBI08 RS01510
gene id: 1215089:BBI08_RS01510
uniprot id: A0A1C7DTG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1215089:BBI08 RS09560
gene id: 1215089:BBI08_RS09560
uniprot id: A0A1C7DPJ4
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1215089:BBI08 RS07035
gene id: 1215089:BBI08_RS07035
uniprot id: A0A1C7DMW3
names: Similarity
messages: Belongs to the UPF0758 family.

1215089:BBI08 RS01625
gene id: 1215089:BBI08_RS01625
uniprot id: A0A1C7DTE3
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1215089:BBI08 RS00245
gene id: 1215089:BBI08_RS00245
uniprot id: A0A1C7DSV1
names: Similarity
messages: Belongs to the RutC family.

1215089:BBI08 RS01085
gene id: 1215089:BBI08_RS01085
uniprot id: A0A1C7DU27
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1215089:BBI08 RS02800
gene id: 1215089:BBI08_RS02800
uniprot id: A0A1C7DUH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1215089:BBI08 RS02685
gene id: 1215089:BBI08_RS02685
uniprot id: A0A1C7DUM1
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

1215089:BBI08 RS12735
gene id: 1215089:BBI08_RS12735
uniprot id: A0A1C7DRG1
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS02630
gene id: 1215089:BBI08_RS02630
uniprot id: A0A1C7DW88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS04465
gene id: 1215089:BBI08_RS04465
uniprot id: A0A1C7DLJ4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GGGP/HepGP synthase family. Group I subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales.

1215089:BBI08 RS14395
gene id: 1215089:BBI08_RS14395
uniprot id: A0A1C7DRB6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS00370
gene id: 1215089:BBI08_RS00370
uniprot id: A0A1C7DTH9
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1215089:BBI08 RS16550
gene id: 1215089:BBI08_RS16550
uniprot id: A0A1C7DSZ8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1215089:BBI08 RS11345
gene id: 1215089:BBI08_RS11345
uniprot id: A0A1C7DPR6
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1215089:BBI08 RS03140
gene id: 1215089:BBI08_RS03140
uniprot id: A0A1C7DVE8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1215089:BBI08 RS03170
gene id: 1215089:BBI08_RS03170
uniprot id: A0A1C7DUC3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1215089:BBI08 RS04175
gene id: 1215089:BBI08_RS04175
uniprot id: A0A1C7DUS2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1215089:BBI08 RS00975
gene id: 1215089:BBI08_RS00975
uniprot id: A0A1C7DTF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1215089:BBI08 RS00270
gene id: 1215089:BBI08_RS00270
uniprot id: A0A1C7DTF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1215089:BBI08 RS08775
gene id: 1215089:BBI08_RS08775
uniprot id: A0A1C7DNQ9
names: Similarity
messages: Belongs to the peptidase S58 family.

1215089:BBI08 RS09180
gene id: 1215089:BBI08_RS09180
uniprot id: A0A1C7DNQ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS01065
gene id: 1215089:BBI08_RS01065
uniprot id: A0A1C7DTT8
names: Similarity
messages: Belongs to the bacterial flagellin family.

1215089:BBI08 RS12445
gene id: 1215089:BBI08_RS12445
uniprot id: A0A1C7DQD9
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1215089:BBI08 RS14295
gene id: 1215089:BBI08_RS14295
uniprot id: A0A1C7DSA4
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

1215089:BBI08 RS07095
gene id: 1215089:BBI08_RS07095
uniprot id: A0A1C7DN14
names: Similarity
messages: Belongs to the UPF0735 family.

1215089:BBI08 RS01715
gene id: 1215089:BBI08_RS01715
uniprot id: A0A1C7DU50
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1215089:BBI08 RS05365
gene id: 1215089:BBI08_RS05365
uniprot id: A0A1C7DM74
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1215089:BBI08 RS11400
gene id: 1215089:BBI08_RS11400
uniprot id: A0A1C7DQS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1215089:BBI08 RS00480
gene id: 1215089:BBI08_RS00480
uniprot id: A0A1C7DTH2
names: Activity Regulation
names: Function
names: Similarity
messages: Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.

1215089:BBI08 RS12260
gene id: 1215089:BBI08_RS12260
uniprot id: A0A1C7DQJ0
names: PTM
messages: Binds 1 heme c group covalently per subunit.

1215089:BBI08 RS15875
gene id: 1215089:BBI08_RS15875
uniprot id: A0A1C7DT06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS05690
gene id: 1215089:BBI08_RS05690
uniprot id: A0A1C7DMF9
names: Similarity
messages: Belongs to the HepT RNase toxin family.

1215089:BBI08 RS15175
gene id: 1215089:BBI08_RS15175
uniprot id: A0A1C7DS99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS03110
gene id: 1215089:BBI08_RS03110
uniprot id: A0A1C7DUV2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS14060
gene id: 1215089:BBI08_RS14060
uniprot id: A0A1C7DRM3
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

1215089:BBI08 RS10415
gene id: 1215089:BBI08_RS10415
uniprot id: A0A1C7DPL5
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1215089:BBI08 RS01415
gene id: 1215089:BBI08_RS01415
uniprot id: A0A1C7DTA6
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1215089:BBI08 RS11590
gene id: 1215089:BBI08_RS11590
uniprot id: A0A1C7DQP4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1215089:BBI08 RS08760
gene id: 1215089:BBI08_RS08760
uniprot id: A0A1C7DPJ0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS11000
gene id: 1215089:BBI08_RS11000
uniprot id: A0A1C7DPW8
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

1215089:BBI08 RS11250
gene id: 1215089:BBI08_RS11250
uniprot id: A0A1C7DQC1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS05565
gene id: 1215089:BBI08_RS05565
uniprot id: A0A1C7DLU7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1215089:BBI08 RS10375
gene id: 1215089:BBI08_RS10375
uniprot id: A0A1C7DQ06
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

1215089:BBI08 RS10820
gene id: 1215089:BBI08_RS10820
uniprot id: A0A1C7DQ38
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1215089:BBI08 RS06845
gene id: 1215089:BBI08_RS06845
uniprot id: A0A1C7DMG2
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

1215089:BBI08 RS16805
gene id: 1215089:BBI08_RS16805
uniprot id: A0A1C7DSL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1215089:BBI08 RS04390
gene id: 1215089:BBI08_RS04390
uniprot id: A0A1C7DLU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1215089:BBI08 RS08035
gene id: 1215089:BBI08_RS08035
uniprot id: A0A1C7DNM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1215089:BBI08 RS11315
gene id: 1215089:BBI08_RS11315
uniprot id: A0A1C7DQ65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1215089:BBI08 RS00180
gene id: 1215089:BBI08_RS00180
uniprot id: A0A1C7DTD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YabA family.
messages: Interacts with both DnaA and DnaN, acting as a bridge between these two proteins.
messages: Involved in initiation control of chromosome replication.

1215089:BBI08 RS08070
gene id: 1215089:BBI08_RS08070
uniprot id: A0A1C7DN36
names: Similarity
messages: Belongs to the EamA transporter family.

1215089:BBI08 RS06810
gene id: 1215089:BBI08_RS06810
uniprot id: A0A1C7DNH8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1215089:BBI08 RS05625
gene id: 1215089:BBI08_RS05625
uniprot id: A0A1C7DLW4
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1215089:BBI08 RS14270
gene id: 1215089:BBI08_RS14270
uniprot id: A0A1C7DRL3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS06530
gene id: 1215089:BBI08_RS06530
uniprot id: A0A1C7DMW8
names: Similarity
messages: Belongs to the universal stress protein A family.

1215089:BBI08 RS06870
gene id: 1215089:BBI08_RS06870
uniprot id: A0A1C7DMT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1215089:BBI08 RS07730
gene id: 1215089:BBI08_RS07730
uniprot id: A0A1C7DV31
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1215089:BBI08 RS00925
gene id: 1215089:BBI08_RS00925
uniprot id: A0A1C7DTF1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1215089:BBI08 RS07545
gene id: 1215089:BBI08_RS07545
uniprot id: A0A1C7DNE2
names: Similarity
messages: Belongs to the Fur family.

1215089:BBI08 RS05830
gene id: 1215089:BBI08_RS05830
uniprot id: A0A1C7DM00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily.
messages: Catalyzes the interconversion of ornithine to glutamate semialdehyde.
messages: Cytoplasm

1215089:BBI08 RS13240
gene id: 1215089:BBI08_RS13240
uniprot id: A0A1C7DRD3
names: Similarity
messages: Belongs to the CpsD/CapB family.

1215089:BBI08 RS12550
gene id: 1215089:BBI08_RS12550
uniprot id: A0A1C7DR65
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1215089:BBI08 RS11710
gene id: 1215089:BBI08_RS11710
uniprot id: A0A1C7DPX9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1215089:BBI08 RS00730
gene id: 1215089:BBI08_RS00730
uniprot id: A0A1C7DTM7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1215089:BBI08 RS15030
gene id: 1215089:BBI08_RS15030
uniprot id: A0A1C7DSI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS02850
gene id: 1215089:BBI08_RS02850
uniprot id: A0A1C7DUI2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1215089:BBI08 RS02845
gene id: 1215089:BBI08_RS02845
uniprot id: A0A1C7DUP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1215089:BBI08 RS13915
gene id: 1215089:BBI08_RS13915
uniprot id: A0A1C7DRE7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1215089:BBI08 RS00495
gene id: 1215089:BBI08_RS00495
uniprot id: A0A1C7DST8
names: Similarity
messages: Belongs to the ycf81 family.

1215089:BBI08 RS11055
gene id: 1215089:BBI08_RS11055
uniprot id: A0A1C7DQ63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

1215089:BBI08 RS01670
gene id: 1215089:BBI08_RS01670
uniprot id: A0A1C7DUE6
names: Cofactor
messages: Binds 1 FAD per subunit.

1215089:BBI08 RS00240
gene id: 1215089:BBI08_RS00240
uniprot id: A0A1C7DTM6
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

1215089:BBI08 RS16790
gene id: 1215089:BBI08_RS16790
uniprot id: A0A1C7DTA9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS15005
gene id: 1215089:BBI08_RS15005
uniprot id: A0A1C7DSY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. L-carnitine dehydrogenase subfamily.
messages: Catalyzes the NAD(+)-dependent oxidation of L-carnitine to 3-dehydrocarnitine.
messages: Cytoplasm
messages: Homodimer.

1215089:BBI08 RS13230
gene id: 1215089:BBI08_RS13230
uniprot id: A0A1C7DRE9
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1215089:BBI08 RS14805
gene id: 1215089:BBI08_RS14805
uniprot id: A0A1C7DS87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS12610
gene id: 1215089:BBI08_RS12610
uniprot id: A0A1C7DQH2
names: Similarity
messages: Belongs to the CpsD/CapB family.

1215089:BBI08 RS02840
gene id: 1215089:BBI08_RS02840
uniprot id: A0A1C7DV89
names: Subcellular Location Annotation
messages: Cell membrane

1215089:BBI08 RS15335
gene id: 1215089:BBI08_RS15335
uniprot id: A0A1C7DSC9
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS00970
gene id: 1215089:BBI08_RS00970
uniprot id: A0A1C7DTK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

1215089:BBI08 RS00815
gene id: 1215089:BBI08_RS00815
uniprot id: A0A1C7DTP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

1215089:BBI08 RS08895
gene id: 1215089:BBI08_RS08895
uniprot id: A0A1C7DNK0
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1215089:BBI08 RS10440
gene id: 1215089:BBI08_RS10440
uniprot id: A0A1C7DQ99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

1215089:BBI08 RS07250
gene id: 1215089:BBI08_RS07250
uniprot id: A0A1C7DN44
names: Similarity
messages: Belongs to the UPF0473 family.

1215089:BBI08 RS06605
gene id: 1215089:BBI08_RS06605
uniprot id: A0A1C7DMW1
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1215089:BBI08 RS06850
gene id: 1215089:BBI08_RS06850
uniprot id: A0A1C7DNE0
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1215089:BBI08 RS02835
gene id: 1215089:BBI08_RS02835
uniprot id: A0A1C7DUQ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1215089:BBI08 RS07615
gene id: 1215089:BBI08_RS07615
uniprot id: A0A1C7DNI2
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1215089:BBI08 RS03910
gene id: 1215089:BBI08_RS03910
uniprot id: A0A1C7DVK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS15985
gene id: 1215089:BBI08_RS15985
uniprot id: A0A1C7DS61
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1215089:BBI08 RS14035
gene id: 1215089:BBI08_RS14035
uniprot id: A0A1C7DR51
names: Similarity
messages: Belongs to the EamA transporter family.

1215089:BBI08 RS13375
gene id: 1215089:BBI08_RS13375
uniprot id: A0A1C7DRS3
names: Similarity
messages: Belongs to the peptidase S8 family.

1215089:BBI08 RS12580
gene id: 1215089:BBI08_RS12580
uniprot id: A0A1C7DRL9
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1215089:BBI08 RS06305
gene id: 1215089:BBI08_RS06305
uniprot id: A0A1C7DMI2
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS03840
gene id: 1215089:BBI08_RS03840
uniprot id: A0A1C7DWA6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1215089:BBI08 RS16200
gene id: 1215089:BBI08_RS16200
uniprot id: A0A1C7DTD7
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1215089:BBI08 RS05245
gene id: 1215089:BBI08_RS05245
uniprot id: A0A1C7DMQ6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1215089:BBI08 RS10295
gene id: 1215089:BBI08_RS10295
uniprot id: A0A1C7DPT6
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1215089:BBI08 RS00380
gene id: 1215089:BBI08_RS00380
uniprot id: A0A1C7DTH4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1215089:BBI08 RS14195
gene id: 1215089:BBI08_RS14195
uniprot id: A0A1C7DS85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS10840
gene id: 1215089:BBI08_RS10840
uniprot id: A0A1C7DPT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

1215089:BBI08 RS11765
gene id: 1215089:BBI08_RS11765
uniprot id: A0A1C7DQY9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS07655
gene id: 1215089:BBI08_RS07655
uniprot id: A0A1C7DN62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ComGC family.
messages: Cell membrane
messages: Homodimer.
messages: Required for transformation and DNA binding.

1215089:BBI08 RS06255
gene id: 1215089:BBI08_RS06255
uniprot id: A0A1C7DMH2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS16580
gene id: 1215089:BBI08_RS16580
uniprot id: A0A1C7DSH5
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS11405
gene id: 1215089:BBI08_RS11405
uniprot id: A0A1C7DQE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1215089:BBI08 RS14470
gene id: 1215089:BBI08_RS14470
uniprot id: A0A1C7DRV7
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1215089:BBI08 RS02520
gene id: 1215089:BBI08_RS02520
uniprot id: A0A1C7DUD1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS11370
gene id: 1215089:BBI08_RS11370
uniprot id: A0A1C7DQ73
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1215089:BBI08 RS11575
gene id: 1215089:BBI08_RS11575
uniprot id: A0A1C7DQB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Membrane

1215089:BBI08 RS05395
gene id: 1215089:BBI08_RS05395
uniprot id: A0A1C7DMN6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1215089:BBI08 RS15155
gene id: 1215089:BBI08_RS15155
uniprot id: A0A1C7DSG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS05855
gene id: 1215089:BBI08_RS05855
uniprot id: A0A1C7DMJ3
names: Similarity
messages: Belongs to the EamA transporter family.

1215089:BBI08 RS04710
gene id: 1215089:BBI08_RS04710
uniprot id: A0A1C7DLZ7
names: Similarity
messages: Belongs to the UPF0374 family.

1215089:BBI08 RS13715
gene id: 1215089:BBI08_RS13715
uniprot id: A0A1C7DRT8
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1215089:BBI08 RS10390
gene id: 1215089:BBI08_RS10390
uniprot id: A0A1C7DQ89
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1215089:BBI08 RS01680
gene id: 1215089:BBI08_RS01680
uniprot id: A0A1C7DTF5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1215089:BBI08 RS01275
gene id: 1215089:BBI08_RS01275
uniprot id: A0A1C7DUH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

1215089:BBI08 RS15290
gene id: 1215089:BBI08_RS15290
uniprot id: A0A1C7DSJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

1215089:BBI08 RS09215
gene id: 1215089:BBI08_RS09215
uniprot id: A0A1C7DNZ1
names: Caution
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS01915
gene id: 1215089:BBI08_RS01915
uniprot id: A0A1C7DUT2
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1215089:BBI08 RS13360
gene id: 1215089:BBI08_RS13360
uniprot id: A0A1C7DRM1
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

1215089:BBI08 RS13470
gene id: 1215089:BBI08_RS13470
uniprot id: A0A1C7DQZ4
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS11270
gene id: 1215089:BBI08_RS11270
uniprot id: A0A1C7DQI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS15215
gene id: 1215089:BBI08_RS15215
uniprot id: A0A1C7DT33
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS01100
gene id: 1215089:BBI08_RS01100
uniprot id: A0A1C7DU67
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

1215089:BBI08 RS07735
gene id: 1215089:BBI08_RS07735
uniprot id: A0A1C7DUW7
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1215089:BBI08 RS09705
gene id: 1215089:BBI08_RS09705
uniprot id: A0A1C7DQ18
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS11275
gene id: 1215089:BBI08_RS11275
uniprot id: A0A1C7DPS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS07375
gene id: 1215089:BBI08_RS07375
uniprot id: A0A1C7DNM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1215089:BBI08 RS11580
gene id: 1215089:BBI08_RS11580
uniprot id: A0A1C7DQ67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS11095
gene id: 1215089:BBI08_RS11095
uniprot id: A0A1C7DQ92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS01315
gene id: 1215089:BBI08_RS01315
uniprot id: A0A1C7DUA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

1215089:BBI08 RS16000
gene id: 1215089:BBI08_RS16000
uniprot id: A0A1C7DTH6
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS12330
gene id: 1215089:BBI08_RS12330
uniprot id: A0A1C7DQY3
names: Similarity
messages: Belongs to the IMPACT family.

1215089:BBI08 RS04720
gene id: 1215089:BBI08_RS04720
uniprot id: A0A1C7DLP0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1215089:BBI08 RS02135
gene id: 1215089:BBI08_RS02135
uniprot id: A0A1C7DUX2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1215089:BBI08 RS05045
gene id: 1215089:BBI08_RS05045
uniprot id: A0A1C7DM41
names: Similarity
messages: Belongs to the universal stress protein A family.

1215089:BBI08 RS12020
gene id: 1215089:BBI08_RS12020
uniprot id: A0A1C7DQ30
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1215089:BBI08 RS11615
gene id: 1215089:BBI08_RS11615
uniprot id: A0A1C7DQH7
names: Similarity
messages: Belongs to the UPF0358 family.

1215089:BBI08 RS07605
gene id: 1215089:BBI08_RS07605
uniprot id: A0A1C7DN52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1215089:BBI08 RS11605
gene id: 1215089:BBI08_RS11605
uniprot id: A0A1C7DPW0
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

1215089:BBI08 RS12935
gene id: 1215089:BBI08_RS12935
uniprot id: A0A1C7DQK8
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1215089:BBI08 RS13750
gene id: 1215089:BBI08_RS13750
uniprot id: A0A1C7DRG6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1215089:BBI08 RS08700
gene id: 1215089:BBI08_RS08700
uniprot id: A0A1C7DNY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.

1215089:BBI08 RS04440
gene id: 1215089:BBI08_RS04440
uniprot id: A0A1C7DM80
names: Similarity
messages: Belongs to the GARS family.

1215089:BBI08 RS03750
gene id: 1215089:BBI08_RS03750
uniprot id: A0A1C7DVY0
names: Similarity
messages: Belongs to the PspA/IM30 family.

1215089:BBI08 RS11720
gene id: 1215089:BBI08_RS11720
uniprot id: A0A1C7DQJ8
names: Function
names: Similarity
names: Subunit
messages: A non-essential component of RNA polymerase (RNAP).
messages: Belongs to the RNA polymerase subunit epsilon family.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunit. The core is associated with a delta subunit, and at least one of epsilon or omega. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1215089:BBI08 RS14055
gene id: 1215089:BBI08_RS14055
uniprot id: A0A1C7DRV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1215089:BBI08 RS01030
gene id: 1215089:BBI08_RS01030
uniprot id: A0A1C7DTS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1215089:BBI08 RS04520
gene id: 1215089:BBI08_RS04520
uniprot id: A0A1C7DLT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1215089:BBI08 RS13840
gene id: 1215089:BBI08_RS13840
uniprot id: A0A1C7DRR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1215089:BBI08 RS03215
gene id: 1215089:BBI08_RS03215
uniprot id: A0A1C7DV64
names: Similarity
messages: Belongs to the transpeptidase family.

1215089:BBI08 RS15390
gene id: 1215089:BBI08_RS15390
uniprot id: A0A1C7DS95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1215089:BBI08 RS10050
gene id: 1215089:BBI08_RS10050
uniprot id: A0A1C7DPF1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1215089:BBI08 RS10325
gene id: 1215089:BBI08_RS10325
uniprot id: A0A1C7DPZ6
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS16490
gene id: 1215089:BBI08_RS16490
uniprot id: A0A1C7DSV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS11140
gene id: 1215089:BBI08_RS11140
uniprot id: A0A1C7DQ95
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1215089:BBI08 RS06465
gene id: 1215089:BBI08_RS06465
uniprot id: A0A1C7DML1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1215089:BBI08 RS03795
gene id: 1215089:BBI08_RS03795
uniprot id: A0A1C7DV81
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1215089:BBI08 RS13745
gene id: 1215089:BBI08_RS13745
uniprot id: A0A1C7DRN7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1215089:BBI08 RS01350
gene id: 1215089:BBI08_RS01350
uniprot id: A0A1C7DTY2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS14175
gene id: 1215089:BBI08_RS14175
uniprot id: A0A1C7DRX7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1215089:BBI08 RS01125
gene id: 1215089:BBI08_RS01125
uniprot id: A0A1C7DTN0
names: Similarity
messages: Belongs to the FlgD family.

1215089:BBI08 RS04635
gene id: 1215089:BBI08_RS04635
uniprot id: A0A1C7DLG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS03975
gene id: 1215089:BBI08_RS03975
uniprot id: A0A1C7DUN5
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS03920
gene id: 1215089:BBI08_RS03920
uniprot id: A0A1C7DUM5
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS02405
gene id: 1215089:BBI08_RS02405
uniprot id: A0A1C7DV25
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPase class C family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm

1215089:BBI08 RS15230
gene id: 1215089:BBI08_RS15230
uniprot id: A0A1C7DW47
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1215089:BBI08 RS00255
gene id: 1215089:BBI08_RS00255
uniprot id: A0A1C7DTT2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS11390
gene id: 1215089:BBI08_RS11390
uniprot id: A0A1C7DPU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1215089:BBI08 RS15970
gene id: 1215089:BBI08_RS15970
uniprot id: A0A1C7DSV9
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1215089:BBI08 RS04230
gene id: 1215089:BBI08_RS04230
uniprot id: A0A1C7DUY9
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS11160
gene id: 1215089:BBI08_RS11160
uniprot id: A0A1C7DPZ7
names: Similarity
messages: Belongs to the fabD family.

1215089:BBI08 RS07235
gene id: 1215089:BBI08_RS07235
uniprot id: A0A1C7DN76
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1215089:BBI08 RS06245
gene id: 1215089:BBI08_RS06245
uniprot id: A0A1C7DN71
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1215089:BBI08 RS00205
gene id: 1215089:BBI08_RS00205
uniprot id: A0A1C7DTS2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS06270
gene id: 1215089:BBI08_RS06270
uniprot id: A0A1C7DMS0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1215089:BBI08 RS06645
gene id: 1215089:BBI08_RS06645
uniprot id: A0A1C7DMC0
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Monomer.

1215089:BBI08 RS08830
gene id: 1215089:BBI08_RS08830
uniprot id: A0A1C7DP09
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport.

1215089:BBI08 RS10855
gene id: 1215089:BBI08_RS10855
uniprot id: A0A1C7DPJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

1215089:BBI08 RS07405
gene id: 1215089:BBI08_RS07405
uniprot id: A0A1C7DN83
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1215089:BBI08 RS04050
gene id: 1215089:BBI08_RS04050
uniprot id: A0A1C7DV94
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

1215089:BBI08 RS14155
gene id: 1215089:BBI08_RS14155
uniprot id: A0A1C7DSG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1215089:BBI08 RS10180
gene id: 1215089:BBI08_RS10180
uniprot id: A0A1C7DPR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1215089:BBI08 RS14360
gene id: 1215089:BBI08_RS14360
uniprot id: A0A1C7DSL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS11415
gene id: 1215089:BBI08_RS11415
uniprot id: A0A1C7DQE8
names: Similarity
messages: Belongs to the UPF0749 family.

1215089:BBI08 RS11330
gene id: 1215089:BBI08_RS11330
uniprot id: A0A1C7DQJ5
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS10235
gene id: 1215089:BBI08_RS10235
uniprot id: A0A1C7DP76
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS10300
gene id: 1215089:BBI08_RS10300
uniprot id: A0A1C7DQE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

1215089:BBI08 RS16140
gene id: 1215089:BBI08_RS16140
uniprot id: A0A1C7DSE4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS00805
gene id: 1215089:BBI08_RS00805
uniprot id: A0A1C7DTP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS04420
gene id: 1215089:BBI08_RS04420
uniprot id: A0A1C7DV73
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1215089:BBI08 RS15085
gene id: 1215089:BBI08_RS15085
uniprot id: A0A1C7DRW3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DbpA subfamily.
messages: Contains an N-terminal domain that binds non-specifically to RNA and a C-terminal domain that binds specifically and tightly to hairpin 92 of 23S rRNA.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes.

1215089:BBI08 RS10945
gene id: 1215089:BBI08_RS10945
uniprot id: A0A1C7DPY9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1215089:BBI08 RS02015
gene id: 1215089:BBI08_RS02015
uniprot id: A0A1C7DUN9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1215089:BBI08 RS14940
gene id: 1215089:BBI08_RS14940
uniprot id: A0A1C7DSM1
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

1215089:BBI08 RS13790
gene id: 1215089:BBI08_RS13790
uniprot id: A0A1C7DRQ2
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1215089:BBI08 RS00335
gene id: 1215089:BBI08_RS00335
uniprot id: A0A1C7DTA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1215089:BBI08 RS13255
gene id: 1215089:BBI08_RS13255
uniprot id: A0A1C7DRF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LytR/CpsA/Psr (LCP) family.
messages: Cell membrane
messages: May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG).

1215089:BBI08 RS06515
gene id: 1215089:BBI08_RS06515
uniprot id: A0A1C7DML8
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1215089:BBI08 RS10365
gene id: 1215089:BBI08_RS10365
uniprot id: A0A1C7DPK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1215089:BBI08 RS11660
gene id: 1215089:BBI08_RS11660
uniprot id: A0A1C7DPW9
names: Similarity
messages: Belongs to the UPF0637 family.

1215089:BBI08 RS05175
gene id: 1215089:BBI08_RS05175
uniprot id: A0A1C7DLN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.

1215089:BBI08 RS14660
gene id: 1215089:BBI08_RS14660
uniprot id: A0A1C7DSH3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1215089:BBI08 RS05990
gene id: 1215089:BBI08_RS05990
uniprot id: A0A1C7DMM2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

1215089:BBI08 RS16225
gene id: 1215089:BBI08_RS16225
uniprot id: A0A1C7DSU6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1215089:BBI08 RS05530
gene id: 1215089:BBI08_RS05530
uniprot id: A0A1C7DMV7
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS00350
gene id: 1215089:BBI08_RS00350
uniprot id: A0A1C7DTP8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

1215089:BBI08 RS08815
gene id: 1215089:BBI08_RS08815
uniprot id: A0A1C7DP13
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1215089:BBI08 RS14335
gene id: 1215089:BBI08_RS14335
uniprot id: A0A1C7DS58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1215089:BBI08 RS13155
gene id: 1215089:BBI08_RS13155
uniprot id: A0A1C7DQT1
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1215089:BBI08 RS14275
gene id: 1215089:BBI08_RS14275
uniprot id: A0A1C7DRZ6
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1215089:BBI08 RS10095
gene id: 1215089:BBI08_RS10095
uniprot id: A0A1C7DPH9
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

1215089:BBI08 RS10975
gene id: 1215089:BBI08_RS10975
uniprot id: A0A1C7DQK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1215089:BBI08 RS08600
gene id: 1215089:BBI08_RS08600
uniprot id: A0A1C7DNX0
names: Similarity
messages: Belongs to the TPP enzyme family.

1215089:BBI08 RS14185
gene id: 1215089:BBI08_RS14185
uniprot id: A0A1C7DRD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1215089:BBI08 RS06780
gene id: 1215089:BBI08_RS06780
uniprot id: A0A1C7DMV5
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS07625
gene id: 1215089:BBI08_RS07625
uniprot id: A0A1C7DMV4
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1215089:BBI08 RS11170
gene id: 1215089:BBI08_RS11170
uniprot id: A0A1C7DQF7
names: Function
names: Similarity
messages: Belongs to the FapR family.
messages: Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism.

1215089:BBI08 RS14530
gene id: 1215089:BBI08_RS14530
uniprot id: A0A1C7DRR6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1215089:BBI08 RS13000
gene id: 1215089:BBI08_RS13000
uniprot id: A0A1C7DRA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FemABX family.
messages: Cytoplasm

1215089:BBI08 RS03440
gene id: 1215089:BBI08_RS03440
uniprot id: A0A1C7DVF4
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1215089:BBI08 RS00115
gene id: 1215089:BBI08_RS00115
uniprot id: A0A1C7DTK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1215089:BBI08 RS16220
gene id: 1215089:BBI08_RS16220
uniprot id: A0A1C7DSZ9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).

1215089:BBI08 RS03005
gene id: 1215089:BBI08_RS03005
uniprot id: A0A1C7DUI1
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS14365
gene id: 1215089:BBI08_RS14365
uniprot id: A0A1C7DS05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS11010
gene id: 1215089:BBI08_RS11010
uniprot id: A0A1C7DQC6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1215089:BBI08 RS01265
gene id: 1215089:BBI08_RS01265
uniprot id: A0A1C7DU97
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1215089:BBI08 RS03800
gene id: 1215089:BBI08_RS03800
uniprot id: A0A1C7DVH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS06835
gene id: 1215089:BBI08_RS06835
uniprot id: A0A1C7DN31
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

1215089:BBI08 RS14895
gene id: 1215089:BBI08_RS14895
uniprot id: A0A1C7DSA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1215089:BBI08 RS05415
gene id: 1215089:BBI08_RS05415
uniprot id: A0A1C7DM43
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1215089:BBI08 RS12845
gene id: 1215089:BBI08_RS12845
uniprot id: A0A1C7DR80
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1215089:BBI08 RS13565
gene id: 1215089:BBI08_RS13565
uniprot id: A0A1C7DRR0
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1215089:BBI08 RS01075
gene id: 1215089:BBI08_RS01075
uniprot id: A0A1C7DTH5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1215089:BBI08 RS12050
gene id: 1215089:BBI08_RS12050
uniprot id: A0A1C7DQF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adapter protein required for efficient degradation of Spx by ClpXP under non-stress conditions. Interaction with Spx stabilizes Spx and exposes the C-terminus of Spx for recognition and proteolysis by ClpXP.
messages: Belongs to the SpxH family.
messages: Cytoplasm
messages: Interacts with Spx.

1215089:BBI08 RS02390
gene id: 1215089:BBI08_RS02390
uniprot id: A0A1C7DTU0
names: Similarity
messages: Belongs to the peptidase C56 family.

1215089:BBI08 RS06455
gene id: 1215089:BBI08_RS06455
uniprot id: A0A1C7DNA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

1215089:BBI08 RS04220
gene id: 1215089:BBI08_RS04220
uniprot id: A0A1C7DVS5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS13525
gene id: 1215089:BBI08_RS13525
uniprot id: A0A1C7DQV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1215089:BBI08 RS04400
gene id: 1215089:BBI08_RS04400
uniprot id: A0A1C7DLU3
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1215089:BBI08 RS13605
gene id: 1215089:BBI08_RS13605
uniprot id: A0A1C7DR84
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1215089:BBI08 RS02300
gene id: 1215089:BBI08_RS02300
uniprot id: A0A1C7DU63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell membrane
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

1215089:BBI08 RS07205
gene id: 1215089:BBI08_RS07205
uniprot id: A0A1C7DN98
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1215089:BBI08 RS11240
gene id: 1215089:BBI08_RS11240
uniprot id: A0A1C7DQB1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1215089:BBI08 RS16185
gene id: 1215089:BBI08_RS16185
uniprot id: A0A1C7DT64
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS16210
gene id: 1215089:BBI08_RS16210
uniprot id: A0A1C7DT01
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO large chain family. Type IV subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P).
messages: Has no RuBP-carboxylation activity.
messages: Homodimer.

1215089:BBI08 RS09315
gene id: 1215089:BBI08_RS09315
uniprot id: A0A1C7DPA8
names: Subcellular Location Annotation
messages: Cytoplasm

1215089:BBI08 RS10885
gene id: 1215089:BBI08_RS10885
uniprot id: A0A1C7DQ53
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS00910
gene id: 1215089:BBI08_RS00910
uniprot id: A0A1C7DUA6
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

1215089:BBI08 RS14575
gene id: 1215089:BBI08_RS14575
uniprot id: A0A1C7DRY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family. YeeN subfamily.
messages: Cytoplasm

1215089:BBI08 RS00650
gene id: 1215089:BBI08_RS00650
uniprot id: A0A1C7DTZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1215089:BBI08 RS11210
gene id: 1215089:BBI08_RS11210
uniprot id: A0A1C7DQ07
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1215089:BBI08 RS11515
gene id: 1215089:BBI08_RS11515
uniprot id: A0A1C7DR21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1215089:BBI08 RS12265
gene id: 1215089:BBI08_RS12265
uniprot id: A0A1C7DQW8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS00835
gene id: 1215089:BBI08_RS00835
uniprot id: A0A1C7DTY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1215089:BBI08 RS02450
gene id: 1215089:BBI08_RS02450
uniprot id: A0A1C7DUJ8
names: Similarity
messages: Belongs to the universal stress protein A family.

1215089:BBI08 RS01110
gene id: 1215089:BBI08_RS01110
uniprot id: A0A1C7DUE4
names: Subcellular Location Annotation
messages: Cytoplasm

1215089:BBI08 RS00695
gene id: 1215089:BBI08_RS00695
uniprot id: A0A1C7DSX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1215089:BBI08 RS00525
gene id: 1215089:BBI08_RS00525
uniprot id: A0A1C7DT78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

1215089:BBI08 RS06925
gene id: 1215089:BBI08_RS06925
uniprot id: A0A1C7DVK0
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

1215089:BBI08 RS07840
gene id: 1215089:BBI08_RS07840
uniprot id: A0A1C7DNG4
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1215089:BBI08 RS06495
gene id: 1215089:BBI08_RS06495
uniprot id: A0A1C7DN68
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS05390
gene id: 1215089:BBI08_RS05390
uniprot id: A0A1C7DVY7
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1215089:BBI08 RS11570
gene id: 1215089:BBI08_RS11570
uniprot id: A0A1C7DQH6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS04735
gene id: 1215089:BBI08_RS04735
uniprot id: A0A1C7DLH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS04090
gene id: 1215089:BBI08_RS04090
uniprot id: A0A1C7DVX8
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS15575
gene id: 1215089:BBI08_RS15575
uniprot id: A0A1C7DSP0
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1215089:BBI08 RS00120
gene id: 1215089:BBI08_RS00120
uniprot id: A0A1C7DST1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1215089:BBI08 RS05790
gene id: 1215089:BBI08_RS05790
uniprot id: A0A1C7DMV8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1215089:BBI08 RS07450
gene id: 1215089:BBI08_RS07450
uniprot id: A0A1C7DN47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1215089:BBI08 RS05400
gene id: 1215089:BBI08_RS05400
uniprot id: A0A1C7DMA5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1215089:BBI08 RS01220
gene id: 1215089:BBI08_RS01220
uniprot id: A0A1C7DTW5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS09520
gene id: 1215089:BBI08_RS09520
uniprot id: A0A1C7DW69
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

1215089:BBI08 RS08705
gene id: 1215089:BBI08_RS08705
uniprot id: A0A1C7DPI1
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1215089:BBI08 RS04135
gene id: 1215089:BBI08_RS04135
uniprot id: A0A1C7DVF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1215089:BBI08 RS12905
gene id: 1215089:BBI08_RS12905
uniprot id: A0A1C7DR67
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1215089:BBI08 RS13905
gene id: 1215089:BBI08_RS13905
uniprot id: A0A1C7DRR8
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1215089:BBI08 RS07645
gene id: 1215089:BBI08_RS07645
uniprot id: A0A1C7DNF9
names: Similarity
messages: Belongs to the GSP E family.

1215089:BBI08 RS09420
gene id: 1215089:BBI08_RS09420
uniprot id: A0A1C7DPW2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1215089:BBI08 RS10085
gene id: 1215089:BBI08_RS10085
uniprot id: A0A1C7DQ98
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1215089:BBI08 RS06815
gene id: 1215089:BBI08_RS06815
uniprot id: A0A1C7DN02
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1215089:BBI08 RS00065
gene id: 1215089:BBI08_RS00065
uniprot id: A0A1C7DTQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1215089:BBI08 RS05680
gene id: 1215089:BBI08_RS05680
uniprot id: A0A1C7DMT4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1215089:BBI08 RS08955
gene id: 1215089:BBI08_RS08955
uniprot id: A0A1C7DNJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS12760
gene id: 1215089:BBI08_RS12760
uniprot id: A0A1C7DQS4
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1215089:BBI08 RS12140
gene id: 1215089:BBI08_RS12140
uniprot id: A0A1C7DRE1
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1215089:BBI08 RS00745
gene id: 1215089:BBI08_RS00745
uniprot id: A0A1C7DSY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1215089:BBI08 RS01235
gene id: 1215089:BBI08_RS01235
uniprot id: A0A1C7DTP3
names: Subcellular Location Annotation
messages: Cell membrane

1215089:BBI08 RS02715
gene id: 1215089:BBI08_RS02715
uniprot id: A0A1C7DTZ8
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).

1215089:BBI08 RS05605
gene id: 1215089:BBI08_RS05605
uniprot id: A0A1C7DM34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1215089:BBI08 RS06300
gene id: 1215089:BBI08_RS06300
uniprot id: A0A1C7DMP9
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1215089:BBI08 RS11025
gene id: 1215089:BBI08_RS11025
uniprot id: A0A1C7DQL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1215089:BBI08 RS01860
gene id: 1215089:BBI08_RS01860
uniprot id: A0A1C7DUS0
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1215089:BBI08 RS15640
gene id: 1215089:BBI08_RS15640
uniprot id: A0A1C7DSP8
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS05355
gene id: 1215089:BBI08_RS05355
uniprot id: A0A1C7DM36
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

1215089:BBI08 RS10455
gene id: 1215089:BBI08_RS10455
uniprot id: A0A1C7DPX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1215089:BBI08 RS03865
gene id: 1215089:BBI08_RS03865
uniprot id: A0A1C7DUS3
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

1215089:BBI08 RS07610
gene id: 1215089:BBI08_RS07610
uniprot id: A0A1C7DNB9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1215089:BBI08 RS04485
gene id: 1215089:BBI08_RS04485
uniprot id: A0A1C7DLD8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1215089:BBI08 RS01865
gene id: 1215089:BBI08_RS01865
uniprot id: A0A1C7DU81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1215089:BBI08 RS13515
gene id: 1215089:BBI08_RS13515
uniprot id: A0A1C7DRQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1215089:BBI08 RS10065
gene id: 1215089:BBI08_RS10065
uniprot id: A0A1C7DP70
names: Function
names: Similarity
messages: 3'-5' exonuclease.
messages: Belongs to the helicase family. DinG subfamily. Type 2 sub-subfamily.

1215089:BBI08 RS01140
gene id: 1215089:BBI08_RS01140
uniprot id: A0A1C7DU39
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

1215089:BBI08 RS12565
gene id: 1215089:BBI08_RS12565
uniprot id: A0A1C7DRD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS13520
gene id: 1215089:BBI08_RS13520
uniprot id: A0A1C7DR01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1215089:BBI08 RS07230
gene id: 1215089:BBI08_RS07230
uniprot id: A0A1C7DNQ4
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

1215089:BBI08 RS07490
gene id: 1215089:BBI08_RS07490
uniprot id: A0A1C7DNV3
names: PTM
messages: Binds 1 heme c group covalently per subunit.

1215089:BBI08 RS10045
gene id: 1215089:BBI08_RS10045
uniprot id: A0A1C7DPG8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1215089:BBI08 RS14225
gene id: 1215089:BBI08_RS14225
uniprot id: A0A1C7DRY7
names: Similarity
messages: Belongs to the EamA transporter family.

1215089:BBI08 RS04540
gene id: 1215089:BBI08_RS04540
uniprot id: A0A1C7DMA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS16730
gene id: 1215089:BBI08_RS16730
uniprot id: A0A1C7DSY8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1215089:BBI08 RS11020
gene id: 1215089:BBI08_RS11020
uniprot id: A0A1C7DPK6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS12840
gene id: 1215089:BBI08_RS12840
uniprot id: A0A1C7DRH9
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1215089:BBI08 RS05410
gene id: 1215089:BBI08_RS05410
uniprot id: A0A1C7DMA9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1215089:BBI08 RS15935
gene id: 1215089:BBI08_RS15935
uniprot id: A0A1C7DS54
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS09770
gene id: 1215089:BBI08_RS09770
uniprot id: A0A1C7DPI8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1215089:BBI08 RS15975
gene id: 1215089:BBI08_RS15975
uniprot id: A0A1C7DT26
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1215089:BBI08 RS06935
gene id: 1215089:BBI08_RS06935
uniprot id: A0A1C7DMU3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1215089:BBI08 RS01520
gene id: 1215089:BBI08_RS01520
uniprot id: A0A1C7DUE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

1215089:BBI08 RS06540
gene id: 1215089:BBI08_RS06540
uniprot id: A0A1C7DMA0
names: Similarity
messages: Belongs to the UPF0173 family.

1215089:BBI08 RS12955
gene id: 1215089:BBI08_RS12955
uniprot id: A0A1C7DR78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FemABX family.
messages: Cytoplasm

1215089:BBI08 RS12765
gene id: 1215089:BBI08_RS12765
uniprot id: A0A1C7DR66
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1215089:BBI08 RS10980
gene id: 1215089:BBI08_RS10980
uniprot id: A0A1C7DQ68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1215089:BBI08 RS11060
gene id: 1215089:BBI08_RS11060
uniprot id: A0A1C7DQD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1215089:BBI08 RS06915
gene id: 1215089:BBI08_RS06915
uniprot id: A0A1C7DN17
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS06940
gene id: 1215089:BBI08_RS06940
uniprot id: A0A1C7DMR3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1215089:BBI08 RS00340
gene id: 1215089:BBI08_RS00340
uniprot id: A0A1C7DT58
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1215089:BBI08 RS02710
gene id: 1215089:BBI08_RS02710
uniprot id: A0A1C7DU40
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1215089:BBI08 RS01645
gene id: 1215089:BBI08_RS01645
uniprot id: A0A1C7DU37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

1215089:BBI08 RS05600
gene id: 1215089:BBI08_RS05600
uniprot id: A0A1C7DM78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1215089:BBI08 RS02585
gene id: 1215089:BBI08_RS02585
uniprot id: A0A1C7DUV7
names: Subcellular Location Annotation
messages: Cell membrane

1215089:BBI08 RS08520
gene id: 1215089:BBI08_RS08520
uniprot id: A0A1C7DNZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1215089:BBI08 RS02030
gene id: 1215089:BBI08_RS02030
uniprot id: A0A1C7DUV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1215089:BBI08 RS05315
gene id: 1215089:BBI08_RS05315
uniprot id: A0A1C7DM66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1215089:BBI08 RS05360
gene id: 1215089:BBI08_RS05360
uniprot id: A0A1C7DLZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1215089:BBI08 RS13235
gene id: 1215089:BBI08_RS13235
uniprot id: A0A1C7DRY9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

1215089:BBI08 RS12835
gene id: 1215089:BBI08_RS12835
uniprot id: A0A1C7DQI7
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1215089:BBI08 RS06520
gene id: 1215089:BBI08_RS06520
uniprot id: A0A1C7DMI5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
messages: Homodimer.

1215089:BBI08 RS09020
gene id: 1215089:BBI08_RS09020
uniprot id: A0A1C7DNM3
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS04570
gene id: 1215089:BBI08_RS04570
uniprot id: A0A1C7DLU8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1215089:BBI08 RS12095
gene id: 1215089:BBI08_RS12095
uniprot id: A0A1C7DQQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS15910
gene id: 1215089:BBI08_RS15910
uniprot id: A0A1C7DSN4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1215089:BBI08 RS02970
gene id: 1215089:BBI08_RS02970
uniprot id: A0A1C7DU78
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1215089:BBI08 RS06350
gene id: 1215089:BBI08_RS06350
uniprot id: A0A1C7DN91
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

1215089:BBI08 RS03745
gene id: 1215089:BBI08_RS03745
uniprot id: A0A1C7DVG2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1215089:BBI08 RS09165
gene id: 1215089:BBI08_RS09165
uniprot id: A0A1C7DNY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

1215089:BBI08 RS07590
gene id: 1215089:BBI08_RS07590
uniprot id: A0A1C7DNX6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1215089:BBI08 RS11245
gene id: 1215089:BBI08_RS11245
uniprot id: A0A1C7DQX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1215089:BBI08 RS16445
gene id: 1215089:BBI08_RS16445
uniprot id: A0A1C7DTB8
names: Similarity
messages: Belongs to the MQO family.

1215089:BBI08 RS07090
gene id: 1215089:BBI08_RS07090
uniprot id: A0A1C7DMU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1215089:BBI08 RS10170
gene id: 1215089:BBI08_RS10170
uniprot id: A0A1C7DP69
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS00010
gene id: 1215089:BBI08_RS00010
uniprot id: A0A1C7DTW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1215089:BBI08 RS05225
gene id: 1215089:BBI08_RS05225
uniprot id: A0A1C7DLN8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1215089:BBI08 RS11495
gene id: 1215089:BBI08_RS11495
uniprot id: A0A1C7DPW4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1215089:BBI08 RS04665
gene id: 1215089:BBI08_RS04665
uniprot id: A0A1C7DLS3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS12405
gene id: 1215089:BBI08_RS12405
uniprot id: A0A1C7DR04
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS05020
gene id: 1215089:BBI08_RS05020
uniprot id: A0A1C7DLL1
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS07030
gene id: 1215089:BBI08_RS07030
uniprot id: A0A1C7DN42
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1215089:BBI08 RS05770
gene id: 1215089:BBI08_RS05770
uniprot id: A0A1C7DME3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
messages: Membrane

1215089:BBI08 RS11080
gene id: 1215089:BBI08_RS11080
uniprot id: A0A1C7DQ88
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1215089:BBI08 RS00300
gene id: 1215089:BBI08_RS00300
uniprot id: A0A1C7DSW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.

1215089:BBI08 RS06635
gene id: 1215089:BBI08_RS06635
uniprot id: A0A1C7DMZ1
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1215089:BBI08 RS00825
gene id: 1215089:BBI08_RS00825
uniprot id: A0A1C7DTD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1215089:BBI08 RS13770
gene id: 1215089:BBI08_RS13770
uniprot id: A0A1C7DRV1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1215089:BBI08 RS10935
gene id: 1215089:BBI08_RS10935
uniprot id: A0A1C7DQR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1215089:BBI08 RS16755
gene id: 1215089:BBI08_RS16755
uniprot id: A0A1C7DSK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1215089:BBI08 RS05780
gene id: 1215089:BBI08_RS05780
uniprot id: A0A1C7DLY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS11195
gene id: 1215089:BBI08_RS11195
uniprot id: A0A1C7DQW1
names: Similarity
messages: Belongs to the asp23 family.

1215089:BBI08 RS07480
gene id: 1215089:BBI08_RS07480
uniprot id: A0A1C7DNP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1215089:BBI08 RS12210
gene id: 1215089:BBI08_RS12210
uniprot id: A0A1C7DQI0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddB/RexB type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of AddA and AddB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.

1215089:BBI08 RS14425
gene id: 1215089:BBI08_RS14425
uniprot id: A0A1C7DRP8
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS00050
gene id: 1215089:BBI08_RS00050
uniprot id: A0A1C7DTJ1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1215089:BBI08 RS13220
gene id: 1215089:BBI08_RS13220
uniprot id: A0A1C7DQQ7
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1215089:BBI08 RS00550
gene id: 1215089:BBI08_RS00550
uniprot id: A0A1C7DTX5
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1215089:BBI08 RS05675
gene id: 1215089:BBI08_RS05675
uniprot id: A0A1C7DLX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1215089:BBI08 RS15710
gene id: 1215089:BBI08_RS15710
uniprot id: A0A1C7DSX7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS02395
gene id: 1215089:BBI08_RS02395
uniprot id: A0A1C7DUW2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Cell membrane
messages: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1215089:BBI08 RS07780
gene id: 1215089:BBI08_RS07780
uniprot id: A0A1C7DN81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1215089:BBI08 RS04515
gene id: 1215089:BBI08_RS04515
uniprot id: A0A1C7DLK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS07070
gene id: 1215089:BBI08_RS07070
uniprot id: A0A1C7DN48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1215089:BBI08 RS13585
gene id: 1215089:BBI08_RS13585
uniprot id: A0A1C7DRL5
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1215089:BBI08 RS01930
gene id: 1215089:BBI08_RS01930
uniprot id: A0A1C7DTY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1215089:BBI08 RS07080
gene id: 1215089:BBI08_RS07080
uniprot id: A0A1C7DN51
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1215089:BBI08 RS03980
gene id: 1215089:BBI08_RS03980
uniprot id: A0A1C7DVR9
names: Similarity
messages: Belongs to the CapA family.

1215089:BBI08 RS11445
gene id: 1215089:BBI08_RS11445
uniprot id: A0A1C7DPV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsL family.
messages: Cell membrane
messages: Essential cell division protein.
messages: Membrane

1215089:BBI08 RS15360
gene id: 1215089:BBI08_RS15360
uniprot id: A0A1C7DRV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1215089:BBI08 RS10125
gene id: 1215089:BBI08_RS10125
uniprot id: A0A1C7DQ35
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS15505
gene id: 1215089:BBI08_RS15505
uniprot id: A0A1C7DS39
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

1215089:BBI08 RS02365
gene id: 1215089:BBI08_RS02365
uniprot id: A0A1C7DU72
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS10900
gene id: 1215089:BBI08_RS10900
uniprot id: A0A1C7DPU9
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1215089:BBI08 RS06030
gene id: 1215089:BBI08_RS06030
uniprot id: A0A1C7DVV5
names: Similarity
messages: Belongs to the Dps family.

1215089:BBI08 RS07115
gene id: 1215089:BBI08_RS07115
uniprot id: A0A1C7DNI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1215089:BBI08 RS12495
gene id: 1215089:BBI08_RS12495
uniprot id: A0A1C7DW93
names: Similarity
messages: Belongs to the malate synthase family.

1215089:BBI08 RS10075
gene id: 1215089:BBI08_RS10075
uniprot id: A0A1C7DQ24
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1215089:BBI08 RS13070
gene id: 1215089:BBI08_RS13070
uniprot id: A0A1C7DW65
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1215089:BBI08 RS15025
gene id: 1215089:BBI08_RS15025
uniprot id: A0A1C7DSD2
names: Subcellular Location Annotation
messages: Cell membrane

1215089:BBI08 RS15125
gene id: 1215089:BBI08_RS15125
uniprot id: A0A1C7DS40
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1215089:BBI08 RS16215
gene id: 1215089:BBI08_RS16215
uniprot id: A0A1C7DTL4
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. MtnX family.
messages: Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).

1215089:BBI08 RS03770
gene id: 1215089:BBI08_RS03770
uniprot id: A0A1C7DV75
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS11560
gene id: 1215089:BBI08_RS11560
uniprot id: A0A1C7DQG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1215089:BBI08 RS08585
gene id: 1215089:BBI08_RS08585
uniprot id: A0A1C7DND9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1215089:BBI08 RS08780
gene id: 1215089:BBI08_RS08780
uniprot id: A0A1C7DNZ9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1215089:BBI08 RS10110
gene id: 1215089:BBI08_RS10110
uniprot id: A0A1C7DPV6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS05250
gene id: 1215089:BBI08_RS05250
uniprot id: A0A1C7DM79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1215089:BBI08 RS13600
gene id: 1215089:BBI08_RS13600
uniprot id: A0A1C7DRD5
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1215089:BBI08 RS14350
gene id: 1215089:BBI08_RS14350
uniprot id: A0A1C7DSB2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1215089:BBI08 RS13625
gene id: 1215089:BBI08_RS13625
uniprot id: A0A1C7DQX3
names: Similarity
messages: Belongs to the FBPase class 2 family.

1215089:BBI08 RS16280
gene id: 1215089:BBI08_RS16280
uniprot id: A0A1C7DSQ5
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1215089:BBI08 RS13530
gene id: 1215089:BBI08_RS13530
uniprot id: A0A1C7DRV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1215089:BBI08 RS06025
gene id: 1215089:BBI08_RS06025
uniprot id: A0A1C7DMJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1215089:BBI08 RS05760
gene id: 1215089:BBI08_RS05760
uniprot id: A0A1C7DMA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS16435
gene id: 1215089:BBI08_RS16435
uniprot id: A0A1C7DSU0
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS01500
gene id: 1215089:BBI08_RS01500
uniprot id: A0A1C7DU11
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1215089:BBI08 RS01090
gene id: 1215089:BBI08_RS01090
uniprot id: A0A1C7DT91
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1215089:BBI08 RS13480
gene id: 1215089:BBI08_RS13480
uniprot id: A0A1C7DRU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1215089:BBI08 RS04015
gene id: 1215089:BBI08_RS04015
uniprot id: A0A1C7DVM5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS06965
gene id: 1215089:BBI08_RS06965
uniprot id: A0A1C7DNF8
names: Function
messages: Required for transformation and DNA binding.

1215089:BBI08 RS06430
gene id: 1215089:BBI08_RS06430
uniprot id: A0A1C7DMV1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family. L-methionine gamma-lyase subfamily.

1215089:BBI08 RS05420
gene id: 1215089:BBI08_RS05420
uniprot id: A0A1C7DM06
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1215089:BBI08 RS16300
gene id: 1215089:BBI08_RS16300
uniprot id: A0A1C7DSC2
names: Similarity
messages: Belongs to the UxaA family.

1215089:BBI08 RS04140
gene id: 1215089:BBI08_RS04140
uniprot id: A0A1C7DVY9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS13805
gene id: 1215089:BBI08_RS13805
uniprot id: A0A1C7DRH3
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

1215089:BBI08 RS01600
gene id: 1215089:BBI08_RS01600
uniprot id: A0A1C7DTW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

1215089:BBI08 RS03010
gene id: 1215089:BBI08_RS03010
uniprot id: A0A1C7DUT3
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1215089:BBI08 RS12755
gene id: 1215089:BBI08_RS12755
uniprot id: A0A1C7DQX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1215089:BBI08 RS06445
gene id: 1215089:BBI08_RS06445
uniprot id: A0A1C7DN57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EzrA family.
messages: Cell membrane
messages: Membrane
messages: Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization.

1215089:BBI08 RS15070
gene id: 1215089:BBI08_RS15070
uniprot id: A0A1C7DS23
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1215089:BBI08 RS01925
gene id: 1215089:BBI08_RS01925
uniprot id: A0A1C7DU25
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS16720
gene id: 1215089:BBI08_RS16720
uniprot id: A0A1C7DT95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1215089:BBI08 RS14710
gene id: 1215089:BBI08_RS14710
uniprot id: A0A1C7DS72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS00070
gene id: 1215089:BBI08_RS00070
uniprot id: A0A1C7DTC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

1215089:BBI08 RS14635
gene id: 1215089:BBI08_RS14635
uniprot id: A0A1C7DRT6
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

1215089:BBI08 RS07470
gene id: 1215089:BBI08_RS07470
uniprot id: A0A1C7DMU5
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

1215089:BBI08 RS06575
gene id: 1215089:BBI08_RS06575
uniprot id: A0A1C7DMI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1215089:BBI08 RS07025
gene id: 1215089:BBI08_RS07025
uniprot id: A0A1C7DNL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

1215089:BBI08 RS13690
gene id: 1215089:BBI08_RS13690
uniprot id: A0A1C7DS80
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1215089:BBI08 RS06500
gene id: 1215089:BBI08_RS06500
uniprot id: A0A1C7DMU2
names: Similarity
messages: Belongs to the universal stress protein A family.

1215089:BBI08 RS04325
gene id: 1215089:BBI08_RS04325
uniprot id: A0A1C7DVX7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1215089:BBI08 RS04760
gene id: 1215089:BBI08_RS04760
uniprot id: A0A1C7DM09
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1215089:BBI08 RS03030
gene id: 1215089:BBI08_RS03030
uniprot id: A0A1C7DV72
names: Similarity
messages: Belongs to the UPF0309 family.

1215089:BBI08 RS11150
gene id: 1215089:BBI08_RS11150
uniprot id: A0A1C7DQA4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1215089:BBI08 RS09175
gene id: 1215089:BBI08_RS09175
uniprot id: A0A1C7DPB6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS06265
gene id: 1215089:BBI08_RS06265
uniprot id: A0A1C7DMK9
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS05705
gene id: 1215089:BBI08_RS05705
uniprot id: A0A1C7DM98
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1215089:BBI08 RS10260
gene id: 1215089:BBI08_RS10260
uniprot id: A0A1C7DPL2
names: Similarity
messages: Belongs to the asparaginase 1 family.

1215089:BBI08 RS09660
gene id: 1215089:BBI08_RS09660
uniprot id: A0A1C7DP94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

1215089:BBI08 RS00830
gene id: 1215089:BBI08_RS00830
uniprot id: A0A1C7DTP9
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1215089:BBI08 RS09980
gene id: 1215089:BBI08_RS09980
uniprot id: A0A1C7DQ75
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

1215089:BBI08 RS02140
gene id: 1215089:BBI08_RS02140
uniprot id: A0A1C7DUC8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1215089:BBI08 RS12350
gene id: 1215089:BBI08_RS12350
uniprot id: A0A1C7DR94
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1215089:BBI08 RS04410
gene id: 1215089:BBI08_RS04410
uniprot id: A0A1C7DLI8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1215089:BBI08 RS01595
gene id: 1215089:BBI08_RS01595
uniprot id: A0A1C7DU28
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

1215089:BBI08 RS04350
gene id: 1215089:BBI08_RS04350
uniprot id: A0A1C7DVI2
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1215089:BBI08 RS13760
gene id: 1215089:BBI08_RS13760
uniprot id: A0A1C7DVF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1215089:BBI08 RS14865
gene id: 1215089:BBI08_RS14865
uniprot id: A0A1C7DRY1
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1215089:BBI08 RS04040
gene id: 1215089:BBI08_RS04040
uniprot id: A0A1C7DVW9
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1215089:BBI08 RS08860
gene id: 1215089:BBI08_RS08860
uniprot id: A0A1C7DPK8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS01290
gene id: 1215089:BBI08_RS01290
uniprot id: A0A1C7DTL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS03615
gene id: 1215089:BBI08_RS03615
uniprot id: A0A1C7DV46
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1215089:BBI08 RS02870
gene id: 1215089:BBI08_RS02870
uniprot id: A0A1C7DU58
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS06905
gene id: 1215089:BBI08_RS06905
uniprot id: A0A1C7DMH4
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1215089:BBI08 RS10345
gene id: 1215089:BBI08_RS10345
uniprot id: A0A1C7DPU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpB family.
messages: Cytoplasm
messages: Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

1215089:BBI08 RS10340
gene id: 1215089:BBI08_RS10340
uniprot id: A0A1C7DQ79
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1215089:BBI08 RS04590
gene id: 1215089:BBI08_RS04590
uniprot id: A0A1C7DMB2
names: Similarity
messages: Belongs to the DinB family.

1215089:BBI08 RS04355
gene id: 1215089:BBI08_RS04355
uniprot id: A0A1C7DLB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS11215
gene id: 1215089:BBI08_RS11215
uniprot id: A0A1C7DQ94
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1215089:BBI08 RS04195
gene id: 1215089:BBI08_RS04195
uniprot id: A0A1C7DVG0
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS15675
gene id: 1215089:BBI08_RS15675
uniprot id: A0A1C7DT27
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1215089:BBI08 RS13695
gene id: 1215089:BBI08_RS13695
uniprot id: A0A1C7DRM6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1215089:BBI08 RS13830
gene id: 1215089:BBI08_RS13830
uniprot id: A0A1C7DR16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1215089:BBI08 RS01095
gene id: 1215089:BBI08_RS01095
uniprot id: A0A1C7DT44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

1215089:BBI08 RS00810
gene id: 1215089:BBI08_RS00810
uniprot id: A0A1C7DU96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

1215089:BBI08 RS10160
gene id: 1215089:BBI08_RS10160
uniprot id: A0A1C7DPW6
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

1215089:BBI08 RS00560
gene id: 1215089:BBI08_RS00560
uniprot id: A0A1C7DU46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1215089:BBI08 RS11175
gene id: 1215089:BBI08_RS11175
uniprot id: A0A1C7DPQ2
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1215089:BBI08 RS11360
gene id: 1215089:BBI08_RS11360
uniprot id: A0A1C7DQZ5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1215089:BBI08 RS11050
gene id: 1215089:BBI08_RS11050
uniprot id: A0A1C7DPX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1215089:BBI08 RS10990
gene id: 1215089:BBI08_RS10990
uniprot id: A0A1C7DQ71
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1215089:BBI08 RS06630
gene id: 1215089:BBI08_RS06630
uniprot id: A0A1C7DMT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1215089:BBI08 RS12775
gene id: 1215089:BBI08_RS12775
uniprot id: A0A1C7DQK1
names: Similarity
messages: Belongs to the threonine aldolase family.

1215089:BBI08 RS14455
gene id: 1215089:BBI08_RS14455
uniprot id: A0A1C7DS24
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS10070
gene id: 1215089:BBI08_RS10070
uniprot id: A0A1C7DP49
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1215089:BBI08 RS13640
gene id: 1215089:BBI08_RS13640
uniprot id: A0A1C7DS70
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1215089:BBI08 RS07155
gene id: 1215089:BBI08_RS07155
uniprot id: A0A1C7DMN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1215089:BBI08 RS07765
gene id: 1215089:BBI08_RS07765
uniprot id: A0A1C7DNH9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1215089:BBI08 RS13595
gene id: 1215089:BBI08_RS13595
uniprot id: A0A1C7DRK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1215089:BBI08 RS00330
gene id: 1215089:BBI08_RS00330
uniprot id: A0A1C7DTG3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1215089:BBI08 RS16700
gene id: 1215089:BBI08_RS16700
uniprot id: A0A1C7DSJ1
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1215089:BBI08 RS07045
gene id: 1215089:BBI08_RS07045
uniprot id: A0A1C7DN04
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1215089:BBI08 RS00720
gene id: 1215089:BBI08_RS00720
uniprot id: A0A1C7DTF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1215089:BBI08 RS01700
gene id: 1215089:BBI08_RS01700
uniprot id: A0A1C7DU48
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.

1215089:BBI08 RS03945
gene id: 1215089:BBI08_RS03945
uniprot id: A0A1C7DVA8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS01710
gene id: 1215089:BBI08_RS01710
uniprot id: A0A1C7DTU3
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

1215089:BBI08 RS11920
gene id: 1215089:BBI08_RS11920
uniprot id: A0A1C7DQP2
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS16600
gene id: 1215089:BBI08_RS16600
uniprot id: A0A1C7DT71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS11455
gene id: 1215089:BBI08_RS11455
uniprot id: A0A1C7DQT6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1215089:BBI08 RS03475
gene id: 1215089:BBI08_RS03475
uniprot id: A0A1C7DV26
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

1215089:BBI08 RS02240
gene id: 1215089:BBI08_RS02240
uniprot id: A0A1C7DUE7
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS10315
gene id: 1215089:BBI08_RS10315
uniprot id: A0A1C7DPJ5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS06760
gene id: 1215089:BBI08_RS06760
uniprot id: A0A1C7DNG9
names: Function
messages: Required for transformation and DNA binding.

1215089:BBI08 RS06380
gene id: 1215089:BBI08_RS06380
uniprot id: A0A1C7DM77
names: Function
messages: Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions.

1215089:BBI08 RS07475
gene id: 1215089:BBI08_RS07475
uniprot id: A0A1C7DMS7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1215089:BBI08 RS10985
gene id: 1215089:BBI08_RS10985
uniprot id: A0A1C7DQS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1215089:BBI08 RS06510
gene id: 1215089:BBI08_RS06510
uniprot id: A0A1C7DMU0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS00645
gene id: 1215089:BBI08_RS00645
uniprot id: A0A1C7DSW5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1215089:BBI08 RS05275
gene id: 1215089:BBI08_RS05275
uniprot id: A0A1C7DLP9
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

1215089:BBI08 RS01475
gene id: 1215089:BBI08_RS01475
uniprot id: A0A1C7DU13
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1215089:BBI08 RS12010
gene id: 1215089:BBI08_RS12010
uniprot id: A0A1C7DQW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1215089:BBI08 RS00900
gene id: 1215089:BBI08_RS00900
uniprot id: A0A1C7DU32
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1215089:BBI08 RS11460
gene id: 1215089:BBI08_RS11460
uniprot id: A0A1C7DQE9
names: Function
names: Similarity
messages: Belongs to the BshC family.
messages: Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH.

1215089:BBI08 RS13720
gene id: 1215089:BBI08_RS13720
uniprot id: A0A1C7DR45
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1215089:BBI08 RS01685
gene id: 1215089:BBI08_RS01685
uniprot id: A0A1C7DUH4
names: Similarity
messages: Belongs to the cycloisomerase 2 family.

1215089:BBI08 RS02550
gene id: 1215089:BBI08_RS02550
uniprot id: A0A1C7DUZ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1215089:BBI08 RS15610
gene id: 1215089:BBI08_RS15610
uniprot id: A0A1C7DS53
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

1215089:BBI08 RS04260
gene id: 1215089:BBI08_RS04260
uniprot id: A0A1C7DVD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1215089:BBI08 RS14930
gene id: 1215089:BBI08_RS14930
uniprot id: A0A1C7DRS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS08420
gene id: 1215089:BBI08_RS08420
uniprot id: A0A1C7DP61
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS15120
gene id: 1215089:BBI08_RS15120
uniprot id: A0A1C7DS89
names: Similarity
messages: Belongs to the glutamate synthase family.

1215089:BBI08 RS14015
gene id: 1215089:BBI08_RS14015
uniprot id: A0A1C7DRG7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.

1215089:BBI08 RS11470
gene id: 1215089:BBI08_RS11470
uniprot id: A0A1C7DQF8
names: Similarity
messages: Belongs to the ketopantoate reductase family.

1215089:BBI08 RS09670
gene id: 1215089:BBI08_RS09670
uniprot id: A0A1C7DPF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1215089:BBI08 RS04660
gene id: 1215089:BBI08_RS04660
uniprot id: A0A1C7DLZ1
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1215089:BBI08 RS16025
gene id: 1215089:BBI08_RS16025
uniprot id: A0A1C7DT36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1215089:BBI08 RS06995
gene id: 1215089:BBI08_RS06995
uniprot id: A0A1C7DMZ4
names: Similarity
messages: Belongs to the GSP E family.

1215089:BBI08 RS01025
gene id: 1215089:BBI08_RS01025
uniprot id: A0A1C7DTG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1215089:BBI08 RS03280
gene id: 1215089:BBI08_RS03280
uniprot id: A0A1C7DVC2
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS04980
gene id: 1215089:BBI08_RS04980
uniprot id: A0A1C7DMK2
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1215089:BBI08 RS16695
gene id: 1215089:BBI08_RS16695
uniprot id: A0A1C7DSP1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1215089:BBI08 RS16310
gene id: 1215089:BBI08_RS16310
uniprot id: A0A1C7DT21
names: Similarity
messages: Belongs to the UxaA family.

1215089:BBI08 RS12615
gene id: 1215089:BBI08_RS12615
uniprot id: A0A1C7DQE7
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS02425
gene id: 1215089:BBI08_RS02425
uniprot id: A0A1C7DUH3
names: Similarity
messages: Belongs to the UPF0312 family.

1215089:BBI08 RS05210
gene id: 1215089:BBI08_RS05210
uniprot id: A0A1C7DLW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS01155
gene id: 1215089:BBI08_RS01155
uniprot id: A0A1C7DT54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

1215089:BBI08 RS15235
gene id: 1215089:BBI08_RS15235
uniprot id: A0A1C7DS68
names: Similarity
messages: Belongs to the ThiD family.

1215089:BBI08 RS14180
gene id: 1215089:BBI08_RS14180
uniprot id: A0A1C7DS29
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1215089:BBI08 RS09665
gene id: 1215089:BBI08_RS09665
uniprot id: A0A1C7DP71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1215089:BBI08 RS07740
gene id: 1215089:BBI08_RS07740
uniprot id: A0A1C7DMZ0
names: Similarity
messages: Belongs to the asp23 family.

1215089:BBI08 RS15185
gene id: 1215089:BBI08_RS15185
uniprot id: A0A1C7DSH6
names: Similarity
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit G family.

1215089:BBI08 RS15345
gene id: 1215089:BBI08_RS15345
uniprot id: A0A1C7DSK0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1215089:BBI08 RS05805
gene id: 1215089:BBI08_RS05805
uniprot id: A0A1C7DMH7
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS13630
gene id: 1215089:BBI08_RS13630
uniprot id: A0A1C7DRX8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS08880
gene id: 1215089:BBI08_RS08880
uniprot id: A0A1C7DP19
names: Similarity
messages: Belongs to the MoaD family.

1215089:BBI08 RS15260
gene id: 1215089:BBI08_RS15260
uniprot id: A0A1C7DSU9
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1215089:BBI08 RS00235
gene id: 1215089:BBI08_RS00235
uniprot id: A0A1C7DTE2
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1215089:BBI08 RS04595
gene id: 1215089:BBI08_RS04595
uniprot id: A0A1C7DLY2
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1215089:BBI08 RS07220
gene id: 1215089:BBI08_RS07220
uniprot id: A0A1C7DNK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

1215089:BBI08 RS11090
gene id: 1215089:BBI08_RS11090
uniprot id: A0A1C7DQT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

1215089:BBI08 RS00605
gene id: 1215089:BBI08_RS00605
uniprot id: A0A1C7DTK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1215089:BBI08 RS02535
gene id: 1215089:BBI08_RS02535
uniprot id: A0A1C7DUU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
messages: Cell membrane
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.

1215089:BBI08 RS11125
gene id: 1215089:BBI08_RS11125
uniprot id: A0A1C7DPM5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1215089:BBI08 RS07215
gene id: 1215089:BBI08_RS07215
uniprot id: A0A1C7DMN2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

1215089:BBI08 RS14535
gene id: 1215089:BBI08_RS14535
uniprot id: A0A1C7DS42
names: Similarity
messages: Belongs to the ComB family.

1215089:BBI08 RS00595
gene id: 1215089:BBI08_RS00595
uniprot id: A0A1C7DSV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1215089:BBI08 RS15385
gene id: 1215089:BBI08_RS15385
uniprot id: A0A1C7DSE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1215089:BBI08 RS11420
gene id: 1215089:BBI08_RS11420
uniprot id: A0A1C7DQ84
names: Similarity
messages: Belongs to the UPF0749 family.

1215089:BBI08 RS00780
gene id: 1215089:BBI08_RS00780
uniprot id: A0A1C7DTN7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1215089:BBI08 RS14330
gene id: 1215089:BBI08_RS14330
uniprot id: A0A1C7DS06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1215089:BBI08 RS08255
gene id: 1215089:BBI08_RS08255
uniprot id: A0A1C7DNR7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS11185
gene id: 1215089:BBI08_RS11185
uniprot id: A0A1C7DQN6
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1215089:BBI08 RS13655
gene id: 1215089:BBI08_RS13655
uniprot id: A0A1C7DR99
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

1215089:BBI08 RS12005
gene id: 1215089:BBI08_RS12005
uniprot id: A0A1C7DQR2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1215089:BBI08 RS07345
gene id: 1215089:BBI08_RS07345
uniprot id: A0A1C7DN26
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS14650
gene id: 1215089:BBI08_RS14650
uniprot id: A0A1C7DRM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1215089:BBI08 RS05435
gene id: 1215089:BBI08_RS05435
uniprot id: A0A1C7DME1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1215089:BBI08 RS14910
gene id: 1215089:BBI08_RS14910
uniprot id: A0A1C7DS46
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1215089:BBI08 RS04650
gene id: 1215089:BBI08_RS04650
uniprot id: A0A1C7DLY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1215089:BBI08 RS08685
gene id: 1215089:BBI08_RS08685
uniprot id: A0A1C7DNG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1215089:BBI08 RS07855
gene id: 1215089:BBI08_RS07855
uniprot id: A0A1C7DN09
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1215089:BBI08 RS12190
gene id: 1215089:BBI08_RS12190
uniprot id: A0A1C7DQW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0344 family.
messages: Cell membrane

1215089:BBI08 RS15315
gene id: 1215089:BBI08_RS15315
uniprot id: A0A1C7DSI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1215089:BBI08 RS14290
gene id: 1215089:BBI08_RS14290
uniprot id: A0A1C7DRA0
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

1215089:BBI08 RS12335
gene id: 1215089:BBI08_RS12335
uniprot id: A0A1C7DR24
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1215089:BBI08 RS14505
gene id: 1215089:BBI08_RS14505
uniprot id: A0A1C7DSE3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1215089:BBI08 RS07685
gene id: 1215089:BBI08_RS07685
uniprot id: A0A1C7DNT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1215089:BBI08 RS07965
gene id: 1215089:BBI08_RS07965
uniprot id: A0A1C7DN19
names: Similarity
messages: Belongs to the SCO1/2 family.

1215089:BBI08 RS12145
gene id: 1215089:BBI08_RS12145
uniprot id: A0A1C7DQR6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1215089:BBI08 RS01775
gene id: 1215089:BBI08_RS01775
uniprot id: A0A1C7DUG6
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS02625
gene id: 1215089:BBI08_RS02625
uniprot id: A0A1C7DUC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS07305
gene id: 1215089:BBI08_RS07305
uniprot id: A0A1C7DN54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

1215089:BBI08 RS02665
gene id: 1215089:BBI08_RS02665
uniprot id: A0A1C7DV12
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS16650
gene id: 1215089:BBI08_RS16650
uniprot id: A0A1C7DT80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1215089:BBI08 RS07280
gene id: 1215089:BBI08_RS07280
uniprot id: A0A1C7DN84
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.

1215089:BBI08 RS00665
gene id: 1215089:BBI08_RS00665
uniprot id: A0A1C7DTL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1215089:BBI08 RS06010
gene id: 1215089:BBI08_RS06010
uniprot id: A0A1C7DMX8
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

1215089:BBI08 RS07415
gene id: 1215089:BBI08_RS07415
uniprot id: A0A1C7DNE3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

1215089:BBI08 RS13085
gene id: 1215089:BBI08_RS13085
uniprot id: A0A1C7DRC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1215089:BBI08 RS13615
gene id: 1215089:BBI08_RS13615
uniprot id: A0A1C7DRS1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1215089:BBI08 RS00700
gene id: 1215089:BBI08_RS00700
uniprot id: A0A1C7DU04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1215089:BBI08 RS06320
gene id: 1215089:BBI08_RS06320
uniprot id: A0A1C7DMT1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1215089:BBI08 RS13580
gene id: 1215089:BBI08_RS13580
uniprot id: A0A1C7DRW5
names: Similarity
messages: Belongs to the UPF0340 family.

1215089:BBI08 RS08855
gene id: 1215089:BBI08_RS08855
uniprot id: A0A1C7DP17
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1215089:BBI08 RS13620
gene id: 1215089:BBI08_RS13620
uniprot id: A0A1C7DR25
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS08085
gene id: 1215089:BBI08_RS08085
uniprot id: A0A1C7DP65
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1215089:BBI08 RS05575
gene id: 1215089:BBI08_RS05575
uniprot id: A0A1C7DLV2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1215089:BBI08 RS06355
gene id: 1215089:BBI08_RS06355
uniprot id: A0A1C7DMQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1215089:BBI08 RS13505
gene id: 1215089:BBI08_RS13505
uniprot id: A0A1C7DR64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1215089:BBI08 RS05310
gene id: 1215089:BBI08_RS05310
uniprot id: A0A1C7DLY6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1215089:BBI08 RS13880
gene id: 1215089:BBI08_RS13880
uniprot id: A0A1C7DR23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS14775
gene id: 1215089:BBI08_RS14775
uniprot id: A0A1C7DRP7
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS11725
gene id: 1215089:BBI08_RS11725
uniprot id: A0A1C7DR63
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1215089:BBI08 RS07270
gene id: 1215089:BBI08_RS07270
uniprot id: A0A1C7DMN8
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1215089:BBI08 RS00095
gene id: 1215089:BBI08_RS00095
uniprot id: A0A1C7DT19
names: Similarity
messages: Belongs to the DCK/DGK family.

1215089:BBI08 RS10940
gene id: 1215089:BBI08_RS10940
uniprot id: A0A1C7DQ62
names: Similarity
messages: Belongs to the ribF family.

1215089:BBI08 RS01070
gene id: 1215089:BBI08_RS01070
uniprot id: A0A1C7DTM0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1215089:BBI08 RS01370
gene id: 1215089:BBI08_RS01370
uniprot id: A0A1C7DUB7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS14580
gene id: 1215089:BBI08_RS14580
uniprot id: A0A1C7DRT0
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the NOS family. Bacterial NOS oxygenase subfamily.
messages: Catalyzes the production of nitric oxide.
messages: Homodimer.
messages: This protein is similar to the oxygenase domain of eukaryotic nitric oxide synthases but lacks the reductase domain which, in eukaryotes, is responsible for transfer of electrons to the ferric heme during nitric oxide synthesis.

1215089:BBI08 RS12440
gene id: 1215089:BBI08_RS12440
uniprot id: A0A1C7DR46
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1215089:BBI08 RS00755
gene id: 1215089:BBI08_RS00755
uniprot id: A0A1C7DTN4
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1215089:BBI08 RS07585
gene id: 1215089:BBI08_RS07585
uniprot id: A0A1C7DNE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1215089:BBI08 RS11260
gene id: 1215089:BBI08_RS11260
uniprot id: A0A1C7DQ16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1215089:BBI08 RS02010
gene id: 1215089:BBI08_RS02010
uniprot id: A0A1C7DTL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1215089:BBI08 RS16110
gene id: 1215089:BBI08_RS16110
uniprot id: A0A1C7DSY3
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

1215089:BBI08 RS09415
gene id: 1215089:BBI08_RS09415
uniprot id: A0A1C7DPB1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1215089:BBI08 RS02095
gene id: 1215089:BBI08_RS02095
uniprot id: A0A1C7DU19
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS11685
gene id: 1215089:BBI08_RS11685
uniprot id: A0A1C7DQD4
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1215089:BBI08 RS04550
gene id: 1215089:BBI08_RS04550
uniprot id: A0A1C7DMD8
names: Similarity
messages: Belongs to the peptidase M29 family.

1215089:BBI08 RS16765
gene id: 1215089:BBI08_RS16765
uniprot id: A0A1C7DTA3
names: Similarity
messages: Belongs to the ParB family.

1215089:BBI08 RS04680
gene id: 1215089:BBI08_RS04680
uniprot id: A0A1C7DM20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1215089:BBI08 RS07440
gene id: 1215089:BBI08_RS07440
uniprot id: A0A1C7DNU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

1215089:BBI08 RS01960
gene id: 1215089:BBI08_RS01960
uniprot id: A0A1C7DUN0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS03775
gene id: 1215089:BBI08_RS03775
uniprot id: A0A1C7DVR6
names: Subcellular Location Annotation
messages: Cytoplasm

1215089:BBI08 RS11165
gene id: 1215089:BBI08_RS11165
uniprot id: A0A1C7DQ83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1215089:BBI08 RS09205
gene id: 1215089:BBI08_RS09205
uniprot id: A0A1C7DP88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

1215089:BBI08 RS09475
gene id: 1215089:BBI08_RS09475
uniprot id: A0A1C7DPX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS16775
gene id: 1215089:BBI08_RS16775
uniprot id: A0A1C7DTA5
names: Similarity
messages: Belongs to the ParB family.

1215089:BBI08 RS06930
gene id: 1215089:BBI08_RS06930
uniprot id: A0A1C7DN23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

1215089:BBI08 RS04750
gene id: 1215089:BBI08_RS04750
uniprot id: A0A1C7DM11
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1215089:BBI08 RS05110
gene id: 1215089:BBI08_RS05110
uniprot id: A0A1C7DLU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PrsA family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.

1215089:BBI08 RS14880
gene id: 1215089:BBI08_RS14880
uniprot id: A0A1C7DRR4
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1215089:BBI08 RS16055
gene id: 1215089:BBI08_RS16055
uniprot id: A0A1C7DTI9
names: Similarity
messages: Belongs to the peptidase S51 family.

1215089:BBI08 RS09960
gene id: 1215089:BBI08_RS09960
uniprot id: A0A1C7DP56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1215089:BBI08 RS11365
gene id: 1215089:BBI08_RS11365
uniprot id: A0A1C7DQD8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1215089:BBI08 RS10915
gene id: 1215089:BBI08_RS10915
uniprot id: A0A1C7DPK9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1215089:BBI08 RS14125
gene id: 1215089:BBI08_RS14125
uniprot id: A0A1C7DRX1
names: Similarity
messages: Belongs to the PspA/IM30 family.

1215089:BBI08 RS07285
gene id: 1215089:BBI08_RS07285
uniprot id: A0A1C7DNR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1215089:BBI08 RS13635
gene id: 1215089:BBI08_RS13635
uniprot id: A0A1C7DRM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1215089:BBI08 RS04525
gene id: 1215089:BBI08_RS04525
uniprot id: A0A1C7DLZ2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1215089:BBI08 RS01900
gene id: 1215089:BBI08_RS01900
uniprot id: A0A1C7DTJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1215089:BBI08 RS04470
gene id: 1215089:BBI08_RS04470
uniprot id: A0A1C7DLT0
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1215089:BBI08 RS14810
gene id: 1215089:BBI08_RS14810
uniprot id: A0A1C7DS26
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1215089:BBI08 RS12460
gene id: 1215089:BBI08_RS12460
uniprot id: A0A1C7DR11
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1215089:BBI08 RS16005
gene id: 1215089:BBI08_RS16005
uniprot id: A0A1C7DSW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1215089:BBI08 RS03640
gene id: 1215089:BBI08_RS03640
uniprot id: A0A1C7DV52
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS16410
gene id: 1215089:BBI08_RS16410
uniprot id: A0A1C7DT42
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS01705
gene id: 1215089:BBI08_RS01705
uniprot id: A0A1C7DTY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1215089:BBI08 RS11145
gene id: 1215089:BBI08_RS11145
uniprot id: A0A1C7DQV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1215089:BBI08 RS01040
gene id: 1215089:BBI08_RS01040
uniprot id: A0A1C7DT81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1215089:BBI08 RS01985
gene id: 1215089:BBI08_RS01985
uniprot id: A0A1C7DTZ9
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS15240
gene id: 1215089:BBI08_RS15240
uniprot id: A0A1C7DSI3
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

1215089:BBI08 RS04425
gene id: 1215089:BBI08_RS04425
uniprot id: A0A1C7DLX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1215089:BBI08 RS12785
gene id: 1215089:BBI08_RS12785
uniprot id: A0A1C7DQH8
names: Activity Regulation
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), including enzyme I, and histidine-containing protein (HPr) are required for the phosphorylation, which leads to the activation of the enzyme.

1215089:BBI08 RS09085
gene id: 1215089:BBI08_RS09085
uniprot id: A0A1C7DNL4
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1215089:BBI08 RS00740
gene id: 1215089:BBI08_RS00740
uniprot id: A0A1C7DT32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1215089:BBI08 RS00225
gene id: 1215089:BBI08_RS00225
uniprot id: A0A1C7DT83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1215089:BBI08 RS05850
gene id: 1215089:BBI08_RS05850
uniprot id: A0A1C7DN20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1215089:BBI08 RS13285
gene id: 1215089:BBI08_RS13285
uniprot id: A0A1C7DS00
names: Similarity
messages: Belongs to the peptidase C40 family.

1215089:BBI08 RS06660
gene id: 1215089:BBI08_RS06660
uniprot id: A0A1C7DNE7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

1215089:BBI08 RS05695
gene id: 1215089:BBI08_RS05695
uniprot id: A0A1C7DMY9
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. NagD family.
messages: Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro.

1215089:BBI08 RS12710
gene id: 1215089:BBI08_RS12710
uniprot id: A0A1C7DR50
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

1215089:BBI08 RS13895
gene id: 1215089:BBI08_RS13895
uniprot id: A0A1C7DRS2
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

1215089:BBI08 RS00630
gene id: 1215089:BBI08_RS00630
uniprot id: A0A1C7DTK7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS03050
gene id: 1215089:BBI08_RS03050
uniprot id: A0A1C7DUM8
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS11510
gene id: 1215089:BBI08_RS11510
uniprot id: A0A1C7DQF9
names: Similarity
messages: Belongs to the peptidase S16 family.

1215089:BBI08 RS08340
gene id: 1215089:BBI08_RS08340
uniprot id: A0A1C7DNR0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1215089:BBI08 RS10020
gene id: 1215089:BBI08_RS10020
uniprot id: A0A1C7DP39
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecU family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation.

1215089:BBI08 RS11425
gene id: 1215089:BBI08_RS11425
uniprot id: A0A1C7DQ40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. DivIB subfamily.
messages: Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex.
messages: Cell membrane

1215089:BBI08 RS14870
gene id: 1215089:BBI08_RS14870
uniprot id: A0A1C7DSA2
names: Subcellular Location Annotation
messages: Cytoplasm

1215089:BBI08 RS02370
gene id: 1215089:BBI08_RS02370
uniprot id: A0A1C7DUG4
names: Similarity
messages: Belongs to the TrpC family.

1215089:BBI08 RS16420
gene id: 1215089:BBI08_RS16420
uniprot id: A0A1C7DTQ1
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS05265
gene id: 1215089:BBI08_RS05265
uniprot id: A0A1C7DM58
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

1215089:BBI08 RS06385
gene id: 1215089:BBI08_RS06385
uniprot id: A0A1C7DVZ8
names: Similarity
messages: Belongs to the histone deacetylase family.

1215089:BBI08 RS13080
gene id: 1215089:BBI08_RS13080
uniprot id: A0A1C7DQX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1215089:BBI08 RS04150
gene id: 1215089:BBI08_RS04150
uniprot id: A0A1C7DVB3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1215089:BBI08 RS14545
gene id: 1215089:BBI08_RS14545
uniprot id: A0A1C7DRK9
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS08040
gene id: 1215089:BBI08_RS08040
uniprot id: A0A1C7DNG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1215089:BBI08 RS01435
gene id: 1215089:BBI08_RS01435
uniprot id: A0A1C7DU00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1215089:BBI08 RS13440
gene id: 1215089:BBI08_RS13440
uniprot id: A0A1C7DS31
names: Similarity
messages: Belongs to the peptidase C40 family.

1215089:BBI08 RS07485
gene id: 1215089:BBI08_RS07485
uniprot id: A0A1C7DNC4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1215089:BBI08 RS04395
gene id: 1215089:BBI08_RS04395
uniprot id: A0A1C7DMB3
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1215089:BBI08 RS13510
gene id: 1215089:BBI08_RS13510
uniprot id: A0A1C7DRK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1215089:BBI08 RS04250
gene id: 1215089:BBI08_RS04250
uniprot id: A0A1C7DW16
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1215089:BBI08 RS16395
gene id: 1215089:BBI08_RS16395
uniprot id: A0A1C7DSJ0
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1215089:BBI08 RS02445
gene id: 1215089:BBI08_RS02445
uniprot id: A0A1C7DUX1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1215089:BBI08 RS11410
gene id: 1215089:BBI08_RS11410
uniprot id: A0A1C7DR03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

1215089:BBI08 RS07710
gene id: 1215089:BBI08_RS07710
uniprot id: A0A1C7DNA2
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1215089:BBI08 RS02935
gene id: 1215089:BBI08_RS02935
uniprot id: A0A1C7DUR8
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS16485
gene id: 1215089:BBI08_RS16485
uniprot id: A0A1C7DSZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS00490
gene id: 1215089:BBI08_RS00490
uniprot id: A0A1C7DSY1
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1215089:BBI08 RS16710
gene id: 1215089:BBI08_RS16710
uniprot id: A0A1C7DT94
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

1215089:BBI08 RS07005
gene id: 1215089:BBI08_RS07005
uniprot id: A0A1C7DMK5
names: Function
messages: Required for transformation and DNA binding.

1215089:BBI08 RS01165
gene id: 1215089:BBI08_RS01165
uniprot id: A0A1C7DTV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1215089:BBI08 RS08680
gene id: 1215089:BBI08_RS08680
uniprot id: A0A1C7DP22
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

1215089:BBI08 RS06570
gene id: 1215089:BBI08_RS06570
uniprot id: A0A1C7DMM9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1215089:BBI08 RS16705
gene id: 1215089:BBI08_RS16705
uniprot id: A0A1C7DTM9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1215089:BBI08 RS14385
gene id: 1215089:BBI08_RS14385
uniprot id: A0A1C7DS69
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1215089:BBI08 RS11585
gene id: 1215089:BBI08_RS11585
uniprot id: A0A1C7DQG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1215089:BBI08 RS07400
gene id: 1215089:BBI08_RS07400
uniprot id: A0A1C7DN13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1215089:BBI08 RS12915
gene id: 1215089:BBI08_RS12915
uniprot id: A0A1C7DQV3
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS01145
gene id: 1215089:BBI08_RS01145
uniprot id: A0A1C7DTA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

1215089:BBI08 RS00220
gene id: 1215089:BBI08_RS00220
uniprot id: A0A1C7DTE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

1215089:BBI08 RS01495
gene id: 1215089:BBI08_RS01495
uniprot id: A0A1C7DTQ6
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

1215089:BBI08 RS00760
gene id: 1215089:BBI08_RS00760
uniprot id: A0A1C7DU86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1215089:BBI08 RS02965
gene id: 1215089:BBI08_RS02965
uniprot id: A0A1C7DV14
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
messages: In the C-terminal section; belongs to the MsrB Met sulfoxide reductase family.
messages: In the N-terminal section; belongs to the MsrA Met sulfoxide reductase family.

1215089:BBI08 RS12280
gene id: 1215089:BBI08_RS12280
uniprot id: A0A1C7DQB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1215089:BBI08 RS13165
gene id: 1215089:BBI08_RS13165
uniprot id: A0A1C7DRN3
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1215089:BBI08 RS03185
gene id: 1215089:BBI08_RS03185
uniprot id: A0A1C7DUW6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1215089:BBI08 RS07750
gene id: 1215089:BBI08_RS07750
uniprot id: A0A1C7DNU8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1215089:BBI08 RS03670
gene id: 1215089:BBI08_RS03670
uniprot id: A0A1C7DVP6
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1215089:BBI08 RS05670
gene id: 1215089:BBI08_RS05670
uniprot id: A0A1C7DLW7
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS01810
gene id: 1215089:BBI08_RS01810
uniprot id: A0A1C7DUR1
names: Subcellular Location Annotation
messages: Membrane

1215089:BBI08 RS11395
gene id: 1215089:BBI08_RS11395
uniprot id: A0A1C7DPS4
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1215089:BBI08 RS00735
gene id: 1215089:BBI08_RS00735
uniprot id: A0A1C7DTV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1215089:BBI08 RS02080
gene id: 1215089:BBI08_RS02080
uniprot id: A0A1C7DUW3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1215089:BBI08 RS12850
gene id: 1215089:BBI08_RS12850
uniprot id: A0A1C7DRR9
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

1215089:BBI08 RS15415
gene id: 1215089:BBI08_RS15415
uniprot id: A0A1C7DSY0
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.