1212491:LFA RS04245
gene id: 1212491:LFA_RS04245
uniprot id: A0A098G333
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

1212491:LFA RS03790
gene id: 1212491:LFA_RS03790
uniprot id: A0A098G1F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1212491:LFA RS05790
gene id: 1212491:LFA_RS05790
uniprot id: A0A098G5F0
names: Similarity
messages: Belongs to the UPF0246 family.

1212491:LFA RS00745
gene id: 1212491:LFA_RS00745
uniprot id: A0A098G0Z2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1212491:LFA RS07170
gene id: 1212491:LFA_RS07170
uniprot id: A0A098G4W9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1212491:LFA RS15965
gene id: 1212491:LFA_RS15965
uniprot id: A0A098G8K2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1212491:LFA RS07835
gene id: 1212491:LFA_RS07835
uniprot id: A0A098G3U0
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1212491:LFA RS08345
gene id: 1212491:LFA_RS08345
uniprot id: A0A098G5J9
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

1212491:LFA RS00780
gene id: 1212491:LFA_RS00780
uniprot id: A0A098G0Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1212491:LFA RS00080
gene id: 1212491:LFA_RS00080
uniprot id: A0A098G1Y9
names: Similarity
messages: Belongs to the pirin family.

1212491:LFA RS09025
gene id: 1212491:LFA_RS09025
uniprot id: A0A098G4K1
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1212491:LFA RS06150
gene id: 1212491:LFA_RS06150
uniprot id: A0A098G484
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS01905
gene id: 1212491:LFA_RS01905
uniprot id: A0A098G322
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

1212491:LFA RS07770
gene id: 1212491:LFA_RS07770
uniprot id: A0A098G3S8
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1212491:LFA RS07755
gene id: 1212491:LFA_RS07755
uniprot id: A0A098G6J0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1212491:LFA RS04525
gene id: 1212491:LFA_RS04525
uniprot id: A0A098G3A0
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1212491:LFA RS07965
gene id: 1212491:LFA_RS07965
uniprot id: A0A098G3X3
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

1212491:LFA RS00345
gene id: 1212491:LFA_RS00345
uniprot id: A0A098G0S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.

1212491:LFA RS10835
gene id: 1212491:LFA_RS10835
uniprot id: A0A098G5I9
names: Similarity
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.

1212491:LFA RS01405
gene id: 1212491:LFA_RS01405
uniprot id: A0A098G2S4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1212491:LFA RS05035
gene id: 1212491:LFA_RS05035
uniprot id: A0A098G3I9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

1212491:LFA RS15035
gene id: 1212491:LFA_RS15035
uniprot id: A0A098G823
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS05045
gene id: 1212491:LFA_RS05045
uniprot id: A0A098G3L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell.

1212491:LFA RS11935
gene id: 1212491:LFA_RS11935
uniprot id: A0A098G948
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1212491:LFA RS12085
gene id: 1212491:LFA_RS12085
uniprot id: A0A098G980
names: Cofactor
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.
messages: Binds 1 FAD per subunit.

1212491:LFA RS04770
gene id: 1212491:LFA_RS04770
uniprot id: A0A098G202
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

1212491:LFA RS16165
gene id: 1212491:LFA_RS16165
uniprot id: A0A098GA34
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS15340
gene id: 1212491:LFA_RS15340
uniprot id: A0A098G870
names: Similarity
messages: Belongs to the UPF0758 family.

1212491:LFA RS11330
gene id: 1212491:LFA_RS11330
uniprot id: A0A098G5Y7
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS03510
gene id: 1212491:LFA_RS03510
uniprot id: A0A098G2N0
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS05000
gene id: 1212491:LFA_RS05000
uniprot id: A0A098G249
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1212491:LFA RS16600
gene id: 1212491:LFA_RS16600
uniprot id: A0A098GBS5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS04400
gene id: 1212491:LFA_RS04400
uniprot id: A0A098G4M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1212491:LFA RS07660
gene id: 1212491:LFA_RS07660
uniprot id: A0A098G541
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

1212491:LFA RS17280
gene id: 1212491:LFA_RS17280
uniprot id: A0A098GAM3
names: Similarity
messages: Belongs to the TPP enzyme family.

1212491:LFA RS07555
gene id: 1212491:LFA_RS07555
uniprot id: A0A098G3N7
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

1212491:LFA RS18135
gene id: 1212491:LFA_RS18135
uniprot id: A0A098G9Y9
names: Similarity
messages: Belongs to the transposase 7 family.

1212491:LFA RS17690
gene id: 1212491:LFA_RS17690
uniprot id: A0A098GB04
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1212491:LFA RS07955
gene id: 1212491:LFA_RS07955
uniprot id: A0A098G6R0
names: Similarity
messages: Belongs to the HesB/IscA family.

1212491:LFA RS06120
gene id: 1212491:LFA_RS06120
uniprot id: A0A098G2V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1212491:LFA RS08210
gene id: 1212491:LFA_RS08210
uniprot id: A0A098G421
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS15335
gene id: 1212491:LFA_RS15335
uniprot id: A0A098G872
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS14445
gene id: 1212491:LFA_RS14445
uniprot id: A0A098GAJ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1212491:LFA RS16540
gene id: 1212491:LFA_RS16540
uniprot id: A0A098G8V1
names: Subcellular Location Annotation
messages: Mitochondrion

1212491:LFA RS04640
gene id: 1212491:LFA_RS04640
uniprot id: A0A098G3B0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

1212491:LFA RS11920
gene id: 1212491:LFA_RS11920
uniprot id: A0A098G6A9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS04240
gene id: 1212491:LFA_RS04240
uniprot id: A0A098G4I8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

1212491:LFA RS08130
gene id: 1212491:LFA_RS08130
uniprot id: A0A098G6U1
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1212491:LFA RS12580
gene id: 1212491:LFA_RS12580
uniprot id: A0A098G9H5
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS09570
gene id: 1212491:LFA_RS09570
uniprot id: A0A098G697
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1212491:LFA RS08885
gene id: 1212491:LFA_RS08885
uniprot id: A0A098G5X1
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS05455
gene id: 1212491:LFA_RS05455
uniprot id: A0A098G2D9
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

1212491:LFA RS04715
gene id: 1212491:LFA_RS04715
uniprot id: A0A098G3E3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1212491:LFA RS16340
gene id: 1212491:LFA_RS16340
uniprot id: A0A098G8T1
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1212491:LFA RS16580
gene id: 1212491:LFA_RS16580
uniprot id: A0A098GAC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

1212491:LFA RS15125
gene id: 1212491:LFA_RS15125
uniprot id: A0A098G832
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

1212491:LFA RS04395
gene id: 1212491:LFA_RS04395
uniprot id: A0A098G364
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1212491:LFA RS04690
gene id: 1212491:LFA_RS04690
uniprot id: A0A098G3D7
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1212491:LFA RS12815
gene id: 1212491:LFA_RS12815
uniprot id: A0A098G6T2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1212491:LFA RS14885
gene id: 1212491:LFA_RS14885
uniprot id: A0A098G806
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1212491:LFA RS19125
gene id: 1212491:LFA_RS19125
uniprot id: A0A098GBC8
names: Similarity
messages: Belongs to the transposase 7 family.

1212491:LFA RS06990
gene id: 1212491:LFA_RS06990
uniprot id: A0A098G641
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

1212491:LFA RS14340
gene id: 1212491:LFA_RS14340
uniprot id: A0A098G905
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1212491:LFA RS11840
gene id: 1212491:LFA_RS11840
uniprot id: A0A098G927
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1212491:LFA RS00815
gene id: 1212491:LFA_RS00815
uniprot id: A0A098G104
names: Similarity
messages: Belongs to the HIBADH-related family.

1212491:LFA RS00895
gene id: 1212491:LFA_RS00895
uniprot id: A0A098FZL9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1212491:LFA RS17875
gene id: 1212491:LFA_RS17875
uniprot id: A0A098GB48
names: Similarity
messages: Belongs to the ParB family.

1212491:LFA RS08640
gene id: 1212491:LFA_RS08640
uniprot id: A0A098G499
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS17210
gene id: 1212491:LFA_RS17210
uniprot id: A0A098GAQ7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

1212491:LFA RS11665
gene id: 1212491:LFA_RS11665
uniprot id: A0A098G7F5
names: Similarity
messages: Belongs to the UPF0310 family.

1212491:LFA RS02005
gene id: 1212491:LFA_RS02005
uniprot id: A0A098G0B9
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

1212491:LFA RS16890
gene id: 1212491:LFA_RS16890
uniprot id: A0A098GAI9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1212491:LFA RS16410
gene id: 1212491:LFA_RS16410
uniprot id: A0A098GA85
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1212491:LFA RS17030
gene id: 1212491:LFA_RS17030
uniprot id: A0A098GAH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1212491:LFA RS14830
gene id: 1212491:LFA_RS14830
uniprot id: A0A098G7Z6
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
messages: The transmembrane domain is a dimerization domain.

1212491:LFA RS00035
gene id: 1212491:LFA_RS00035
uniprot id: A0A098G0K8
names: Similarity
messages: Belongs to the agmatine deiminase family.

1212491:LFA RS07155
gene id: 1212491:LFA_RS07155
uniprot id: A0A098G3G3
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1212491:LFA RS08740
gene id: 1212491:LFA_RS08740
uniprot id: A0A098G5T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TamA family.
messages: Cell outer membrane
messages: Membrane

1212491:LFA RS11875
gene id: 1212491:LFA_RS11875
uniprot id: A0A098G650
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS02700
gene id: 1212491:LFA_RS02700
uniprot id: A0A098G272
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS14550
gene id: 1212491:LFA_RS14550
uniprot id: A0A098GAL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1212491:LFA RS16395
gene id: 1212491:LFA_RS16395
uniprot id: A0A098G8S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm

1212491:LFA RS02800
gene id: 1212491:LFA_RS02800
uniprot id: A0A098G3M4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane
messages: CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin).

1212491:LFA RS04110
gene id: 1212491:LFA_RS04110
uniprot id: A0A098G1M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

1212491:LFA RS07405
gene id: 1212491:LFA_RS07405
uniprot id: A0A098G3L0
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

1212491:LFA RS10530
gene id: 1212491:LFA_RS10530
uniprot id: A0A098G5G8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1212491:LFA RS07225
gene id: 1212491:LFA_RS07225
uniprot id: A0A098G3H1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

1212491:LFA RS09270
gene id: 1212491:LFA_RS09270
uniprot id: A0A098G7F4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1212491:LFA RS15145
gene id: 1212491:LFA_RS15145
uniprot id: A0A098G836
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS14395
gene id: 1212491:LFA_RS14395
uniprot id: A0A098GAI1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1212491:LFA RS06365
gene id: 1212491:LFA_RS06365
uniprot id: A0A098G305
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1212491:LFA RS09720
gene id: 1212491:LFA_RS09720
uniprot id: A0A098G4X1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

1212491:LFA RS17650
gene id: 1212491:LFA_RS17650
uniprot id: A0A098GAZ9
names: Function
names: Similarity
messages: Belongs to the ATPase gamma chain family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1212491:LFA RS05520
gene id: 1212491:LFA_RS05520
uniprot id: A0A098G2F1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1212491:LFA RS06745
gene id: 1212491:LFA_RS06745
uniprot id: A0A098G5Z5
names: Similarity
messages: Belongs to the peptidase M1 family.

1212491:LFA RS08680
gene id: 1212491:LFA_RS08680
uniprot id: A0A098G5S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1212491:LFA RS12040
gene id: 1212491:LFA_RS12040
uniprot id: A0A098G7M5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1212491:LFA RS00800
gene id: 1212491:LFA_RS00800
uniprot id: A0A098G101
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1212491:LFA RS12645
gene id: 1212491:LFA_RS12645
uniprot id: A0A098G9I3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1212491:LFA RS11805
gene id: 1212491:LFA_RS11805
uniprot id: A0A098G7M1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1212491:LFA RS08975
gene id: 1212491:LFA_RS08975
uniprot id: A0A098G4J1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1212491:LFA RS00750
gene id: 1212491:LFA_RS00750
uniprot id: A0A098G2E2
names: Similarity
messages: Belongs to the YciI family.

1212491:LFA RS12025
gene id: 1212491:LFA_RS12025
uniprot id: A0A098G682
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1212491:LFA RS03185
gene id: 1212491:LFA_RS03185
uniprot id: A0A098G139
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1212491:LFA RS12860
gene id: 1212491:LFA_RS12860
uniprot id: A0A098G9M1
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1212491:LFA RS09290
gene id: 1212491:LFA_RS09290
uniprot id: A0A098G649
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

1212491:LFA RS03515
gene id: 1212491:LFA_RS03515
uniprot id: A0A098G196
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS08125
gene id: 1212491:LFA_RS08125
uniprot id: A0A098G5F1
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS14405
gene id: 1212491:LFA_RS14405
uniprot id: A0A098G7R1
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1212491:LFA RS11810
gene id: 1212491:LFA_RS11810
uniprot id: A0A098G921
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1212491:LFA RS12130
gene id: 1212491:LFA_RS12130
uniprot id: A0A098G7T9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1212491:LFA RS01240
gene id: 1212491:LFA_RS01240
uniprot id: A0A098G199
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS14865
gene id: 1212491:LFA_RS14865
uniprot id: A0A098G9A0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1212491:LFA RS05795
gene id: 1212491:LFA_RS05795
uniprot id: A0A098G410
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

1212491:LFA RS02200
gene id: 1212491:LFA_RS02200
uniprot id: A0A098G1V7
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1212491:LFA RS04650
gene id: 1212491:LFA_RS04650
uniprot id: A0A098G3C7
names: Similarity
messages: Belongs to the MotB family.

1212491:LFA RS01325
gene id: 1212491:LFA_RS01325
uniprot id: A0A098FZW7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1212491:LFA RS03780
gene id: 1212491:LFA_RS03780
uniprot id: A0A098G492
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1212491:LFA RS16925
gene id: 1212491:LFA_RS16925
uniprot id: A0A098G928
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

1212491:LFA RS08525
gene id: 1212491:LFA_RS08525
uniprot id: A0A098G720
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

1212491:LFA RS10605
gene id: 1212491:LFA_RS10605
uniprot id: A0A098G6U7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1212491:LFA RS04350
gene id: 1212491:LFA_RS04350
uniprot id: A0A098G4L3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

1212491:LFA RS04540
gene id: 1212491:LFA_RS04540
uniprot id: A0A098G391
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1212491:LFA RS16240
gene id: 1212491:LFA_RS16240
uniprot id: A0A098G8R1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

1212491:LFA RS01540
gene id: 1212491:LFA_RS01540
uniprot id: A0A098G003
names: Similarity
messages: Belongs to the UPF0235 family.

1212491:LFA RS11850
gene id: 1212491:LFA_RS11850
uniprot id: A0A098G694
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

1212491:LFA RS01730
gene id: 1212491:LFA_RS01730
uniprot id: A0A098G2Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1212491:LFA RS16025
gene id: 1212491:LFA_RS16025
uniprot id: A0A098G8J6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1212491:LFA RS15325
gene id: 1212491:LFA_RS15325
uniprot id: A0A098GB39
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1212491:LFA RS12975
gene id: 1212491:LFA_RS12975
uniprot id: A0A098G890
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1212491:LFA RS14825
gene id: 1212491:LFA_RS14825
uniprot id: A0A098G9D7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1212491:LFA RS16400
gene id: 1212491:LFA_RS16400
uniprot id: A0A098GA54
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1212491:LFA RS05600
gene id: 1212491:LFA_RS05600
uniprot id: A0A098G2J7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1212491:LFA RS05550
gene id: 1212491:LFA_RS05550
uniprot id: A0A098G2I7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

1212491:LFA RS04430
gene id: 1212491:LFA_RS04430
uniprot id: A0A098G377
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1212491:LFA RS06140
gene id: 1212491:LFA_RS06140
uniprot id: A0A098G2T1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1212491:LFA RS05940
gene id: 1212491:LFA_RS05940
uniprot id: A0A098G2R7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1212491:LFA RS16435
gene id: 1212491:LFA_RS16435
uniprot id: A0A098GA90
names: Similarity
messages: Belongs to the PhoH family.

1212491:LFA RS12740
gene id: 1212491:LFA_RS12740
uniprot id: A0A098G9J8
names: Function
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.

1212491:LFA RS05965
gene id: 1212491:LFA_RS05965
uniprot id: A0A098G2S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell inner membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1212491:LFA RS01615
gene id: 1212491:LFA_RS01615
uniprot id: A0A098G1H1
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

1212491:LFA RS07935
gene id: 1212491:LFA_RS07935
uniprot id: A0A098G5A9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1212491:LFA RS11745
gene id: 1212491:LFA_RS11745
uniprot id: A0A098G674
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1212491:LFA RS12595
gene id: 1212491:LFA_RS12595
uniprot id: A0A098G6L1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1212491:LFA RS16095
gene id: 1212491:LFA_RS16095
uniprot id: A0A098GA18
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1212491:LFA RS07575
gene id: 1212491:LFA_RS07575
uniprot id: A0A098G551
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1212491:LFA RS11440
gene id: 1212491:LFA_RS11440
uniprot id: A0A098G8U5
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

1212491:LFA RS17615
gene id: 1212491:LFA_RS17615
uniprot id: A0A098GAZ2
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.

1212491:LFA RS09995
gene id: 1212491:LFA_RS09995
uniprot id: A0A098G533
names: Similarity
messages: Belongs to the YggT family.

1212491:LFA RS17660
gene id: 1212491:LFA_RS17660
uniprot id: A0A098G9K0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1212491:LFA RS12720
gene id: 1212491:LFA_RS12720
uniprot id: A0A098G847
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1212491:LFA RS10065
gene id: 1212491:LFA_RS10065
uniprot id: A0A098G548
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS04825
gene id: 1212491:LFA_RS04825
uniprot id: A0A098G3E7
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

1212491:LFA RS17055
gene id: 1212491:LFA_RS17055
uniprot id: A0A098GAI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

1212491:LFA RS04550
gene id: 1212491:LFA_RS04550
uniprot id: A0A098G3A6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1212491:LFA RS06370
gene id: 1212491:LFA_RS06370
uniprot id: A0A098G4C8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1212491:LFA RS02540
gene id: 1212491:LFA_RS02540
uniprot id: A0A098G0I9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

1212491:LFA RS04300
gene id: 1212491:LFA_RS04300
uniprot id: A0A098G1P6
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS05510
gene id: 1212491:LFA_RS05510
uniprot id: A0A098G598
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1212491:LFA RS04995
gene id: 1212491:LFA_RS04995
uniprot id: A0A098G3K5
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS05935
gene id: 1212491:LFA_RS05935
uniprot id: A0A098G2N5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1212491:LFA RS06235
gene id: 1212491:LFA_RS06235
uniprot id: A0A098G2Y0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1212491:LFA RS03725
gene id: 1212491:LFA_RS03725
uniprot id: A0A098G1E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1212491:LFA RS18090
gene id: 1212491:LFA_RS18090
uniprot id: A0A098G9U2
names: Similarity
messages: Belongs to the RelE toxin family.

1212491:LFA RS00670
gene id: 1212491:LFA_RS00670
uniprot id: A0A098FZH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1212491:LFA RS05830
gene id: 1212491:LFA_RS05830
uniprot id: A0A098G2P1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1212491:LFA RS15485
gene id: 1212491:LFA_RS15485
uniprot id: A0A098G8A0
names: Subcellular Location Annotation
messages: Cytoplasm

1212491:LFA RS05860
gene id: 1212491:LFA_RS05860
uniprot id: A0A098G5G4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

1212491:LFA RS12240
gene id: 1212491:LFA_RS12240
uniprot id: A0A098G6H6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS14440
gene id: 1212491:LFA_RS14440
uniprot id: A0A098G922
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS01130
gene id: 1212491:LFA_RS01130
uniprot id: A0A098G2M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1212491:LFA RS05575
gene id: 1212491:LFA_RS05575
uniprot id: A0A098G2J2
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS13460
gene id: 1212491:LFA_RS13460
uniprot id: A0A098G8I9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1212491:LFA RS08305
gene id: 1212491:LFA_RS08305
uniprot id: A0A098G5J1
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS00715
gene id: 1212491:LFA_RS00715
uniprot id: A0A098FZI6
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.

1212491:LFA RS01550
gene id: 1212491:LFA_RS01550
uniprot id: A0A098G016
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1212491:LFA RS06310
gene id: 1212491:LFA_RS06310
uniprot id: A0A098G2Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1212491:LFA RS08710
gene id: 1212491:LFA_RS08710
uniprot id: A0A098G4D4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1212491:LFA RS11480
gene id: 1212491:LFA_RS11480
uniprot id: A0A098G5W4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1212491:LFA RS04850
gene id: 1212491:LFA_RS04850
uniprot id: A0A098G3F2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1212491:LFA RS04615
gene id: 1212491:LFA_RS04615
uniprot id: A0A098G3A5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1212491:LFA RS18175
gene id: 1212491:LFA_RS18175
uniprot id: A0A098GBB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1212491:LFA RS03505
gene id: 1212491:LFA_RS03505
uniprot id: A0A098G428
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1212491:LFA RS06825
gene id: 1212491:LFA_RS06825
uniprot id: A0A098G387
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1212491:LFA RS12455
gene id: 1212491:LFA_RS12455
uniprot id: A0A098G6L8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1212491:LFA RS13565
gene id: 1212491:LFA_RS13565
uniprot id: A0A098G8K5
names: Similarity
messages: Belongs to the UPF0276 family.

1212491:LFA RS07850
gene id: 1212491:LFA_RS07850
uniprot id: A0A098G594
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

1212491:LFA RS12050
gene id: 1212491:LFA_RS12050
uniprot id: A0A098G688
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1212491:LFA RS15135
gene id: 1212491:LFA_RS15135
uniprot id: A0A098GAW8
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS16030
gene id: 1212491:LFA_RS16030
uniprot id: A0A098G9Y5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1212491:LFA RS10090
gene id: 1212491:LFA_RS10090
uniprot id: A0A098G555
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1212491:LFA RS17350
gene id: 1212491:LFA_RS17350
uniprot id: A0A098G9A9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1212491:LFA RS17215
gene id: 1212491:LFA_RS17215
uniprot id: A0A098G9B8
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

1212491:LFA RS10615
gene id: 1212491:LFA_RS10615
uniprot id: A0A098G5E7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

1212491:LFA RS05570
gene id: 1212491:LFA_RS05570
uniprot id: A0A098G2G1
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1212491:LFA RS11945
gene id: 1212491:LFA_RS11945
uniprot id: A0A098G6B4
names: Similarity
messages: Belongs to the skp family.

1212491:LFA RS07235
gene id: 1212491:LFA_RS07235
uniprot id: A0A098G4V3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1212491:LFA RS05660
gene id: 1212491:LFA_RS05660
uniprot id: A0A098G3Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1212491:LFA RS01900
gene id: 1212491:LFA_RS01900
uniprot id: A0A098G1N6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

1212491:LFA RS02840
gene id: 1212491:LFA_RS02840
uniprot id: A0A098G2A0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1212491:LFA RS05610
gene id: 1212491:LFA_RS05610
uniprot id: A0A098G5B6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1212491:LFA RS09650
gene id: 1212491:LFA_RS09650
uniprot id: A0A098G6C6
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

1212491:LFA RS15980
gene id: 1212491:LFA_RS15980
uniprot id: A0A098GBF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1212491:LFA RS16080
gene id: 1212491:LFA_RS16080
uniprot id: A0A098G8K6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1212491:LFA RS15515
gene id: 1212491:LFA_RS15515
uniprot id: A0A098G9P6
names: Similarity
messages: Belongs to the P(II) protein family.

1212491:LFA RS15960
gene id: 1212491:LFA_RS15960
uniprot id: A0A098G9Z3
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1212491:LFA RS03315
gene id: 1212491:LFA_RS03315
uniprot id: A0A098G3Y7
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

1212491:LFA RS09880
gene id: 1212491:LFA_RS09880
uniprot id: A0A098G7S2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1212491:LFA RS16700
gene id: 1212491:LFA_RS16700
uniprot id: A0A098GAE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1212491:LFA RS04700
gene id: 1212491:LFA_RS04700
uniprot id: A0A098G1Y8
names: Similarity
messages: Belongs to the peptidase U62 family.

1212491:LFA RS06590
gene id: 1212491:LFA_RS06590
uniprot id: A0A098G4J4
names: Similarity
messages: Belongs to the DSD1 family.

1212491:LFA RS09655
gene id: 1212491:LFA_RS09655
uniprot id: A0A098G7M8
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

1212491:LFA RS18220
gene id: 1212491:LFA_RS18220
uniprot id: A0A098GBC1
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS06300
gene id: 1212491:LFA_RS06300
uniprot id: A0A098G4C6
names: Similarity
messages: Belongs to the RecJ family.

1212491:LFA RS15400
gene id: 1212491:LFA_RS15400
uniprot id: A0A098G9M3
names: Similarity
messages: Belongs to the glycosyl hydrolase 8 (cellulase D) family.

1212491:LFA RS11710
gene id: 1212491:LFA_RS11710
uniprot id: A0A098G901
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1212491:LFA RS02015
gene id: 1212491:LFA_RS02015
uniprot id: A0A098G345
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1212491:LFA RS10495
gene id: 1212491:LFA_RS10495
uniprot id: A0A098G8A1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1212491:LFA RS05630
gene id: 1212491:LFA_RS05630
uniprot id: A0A098G2K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

1212491:LFA RS08145
gene id: 1212491:LFA_RS08145
uniprot id: A0A098G5F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1212491:LFA RS01645
gene id: 1212491:LFA_RS01645
uniprot id: A0A098G038
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1212491:LFA RS17725
gene id: 1212491:LFA_RS17725
uniprot id: A0A098GB11
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1212491:LFA RS04100
gene id: 1212491:LFA_RS04100
uniprot id: A0A098G4G1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1212491:LFA RS01360
gene id: 1212491:LFA_RS01360
uniprot id: A0A098G1C6
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1212491:LFA RS07690
gene id: 1212491:LFA_RS07690
uniprot id: A0A098G6H5
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

1212491:LFA RS02455
gene id: 1212491:LFA_RS02455
uniprot id: A0A098G213
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1212491:LFA RS00400
gene id: 1212491:LFA_RS00400
uniprot id: A0A098FZD2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1212491:LFA RS11715
gene id: 1212491:LFA_RS11715
uniprot id: A0A098G7G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1212491:LFA RS07220
gene id: 1212491:LFA_RS07220
uniprot id: A0A098G4X9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1212491:LFA RS09030
gene id: 1212491:LFA_RS09030
uniprot id: A0A098G4H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

1212491:LFA RS16125
gene id: 1212491:LFA_RS16125
uniprot id: A0A098G8N6
names: Similarity
messages: Belongs to the IucA/IucC family.

1212491:LFA RS10080
gene id: 1212491:LFA_RS10080
uniprot id: A0A098G6J9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1212491:LFA RS07065
gene id: 1212491:LFA_RS07065
uniprot id: A0A098G657
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

1212491:LFA RS11155
gene id: 1212491:LFA_RS11155
uniprot id: A0A098G8N2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1212491:LFA RS11800
gene id: 1212491:LFA_RS11800
uniprot id: A0A098G631
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1212491:LFA RS05490
gene id: 1212491:LFA_RS05490
uniprot id: A0A098G595
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1212491:LFA RS12690
gene id: 1212491:LFA_RS12690
uniprot id: A0A098G840
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1212491:LFA RS05155
gene id: 1212491:LFA_RS05155
uniprot id: A0A098G3L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1212491:LFA RS07640
gene id: 1212491:LFA_RS07640
uniprot id: A0A098G537
names: Function
names: Similarity
messages: Belongs to the FliK family.
messages: Controls the length of the flagellar hook.

1212491:LFA RS08950
gene id: 1212491:LFA_RS08950
uniprot id: A0A098G4I6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1212491:LFA RS15235
gene id: 1212491:LFA_RS15235
uniprot id: A0A098G9J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1212491:LFA RS05565
gene id: 1212491:LFA_RS05565
uniprot id: A0A098G3W4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS08400
gene id: 1212491:LFA_RS08400
uniprot id: A0A098G467
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1212491:LFA RS04235
gene id: 1212491:LFA_RS04235
uniprot id: A0A098G331
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS09790
gene id: 1212491:LFA_RS09790
uniprot id: A0A098G7Q4
names: Subcellular Location Annotation
messages: Cytoplasm

1212491:LFA RS07900
gene id: 1212491:LFA_RS07900
uniprot id: A0A098G3V6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. UgpAE subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).

1212491:LFA RS04020
gene id: 1212491:LFA_RS04020
uniprot id: A0A098G2Y7
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1212491:LFA RS09695
gene id: 1212491:LFA_RS09695
uniprot id: A0A098G4W6
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1212491:LFA RS12825
gene id: 1212491:LFA_RS12825
uniprot id: A0A098G6S1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1212491:LFA RS14505
gene id: 1212491:LFA_RS14505
uniprot id: A0A098G7T1
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS17205
gene id: 1212491:LFA_RS17205
uniprot id: A0A098GC48
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

1212491:LFA RS16065
gene id: 1212491:LFA_RS16065
uniprot id: A0A098GA13
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1212491:LFA RS16005
gene id: 1212491:LFA_RS16005
uniprot id: A0A098G9Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1212491:LFA RS08050
gene id: 1212491:LFA_RS08050
uniprot id: A0A098G6S8
names: Similarity
messages: Belongs to the acylphosphatase family.

1212491:LFA RS18610
gene id: 1212491:LFA_RS18610
uniprot id: A0A098GBL8
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS08585
gene id: 1212491:LFA_RS08585
uniprot id: A0A098G4B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1212491:LFA RS05955
gene id: 1212491:LFA_RS05955
uniprot id: A0A098G447
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1212491:LFA RS12730
gene id: 1212491:LFA_RS12730
uniprot id: A0A098G6Q1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1212491:LFA RS11825
gene id: 1212491:LFA_RS11825
uniprot id: A0A098G638
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1212491:LFA RS05805
gene id: 1212491:LFA_RS05805
uniprot id: A0A098G2N6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1212491:LFA RS15690
gene id: 1212491:LFA_RS15690
uniprot id: A0A098G8E0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS00120
gene id: 1212491:LFA_RS00120
uniprot id: A0A098G1Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

1212491:LFA RS01135
gene id: 1212491:LFA_RS01135
uniprot id: A0A098G172
names: Similarity
messages: Belongs to the Fur family.

1212491:LFA RS15450
gene id: 1212491:LFA_RS15450
uniprot id: A0A098GB58
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1212491:LFA RS08535
gene id: 1212491:LFA_RS08535
uniprot id: A0A098G498
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS14375
gene id: 1212491:LFA_RS14375
uniprot id: A0A098G947
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1212491:LFA RS10120
gene id: 1212491:LFA_RS10120
uniprot id: A0A098G6M2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1212491:LFA RS12135
gene id: 1212491:LFA_RS12135
uniprot id: A0A098G992
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1212491:LFA RS04625
gene id: 1212491:LFA_RS04625
uniprot id: A0A098G3C1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1212491:LFA RS07975
gene id: 1212491:LFA_RS07975
uniprot id: A0A098G5B9
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1212491:LFA RS02860
gene id: 1212491:LFA_RS02860
uniprot id: A0A098G0V8
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1212491:LFA RS12315
gene id: 1212491:LFA_RS12315
uniprot id: A0A098G6J1
names: Similarity
messages: Belongs to the SCO1/2 family.

1212491:LFA RS05815
gene id: 1212491:LFA_RS05815
uniprot id: A0A098G5F3
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

1212491:LFA RS05105
gene id: 1212491:LFA_RS05105
uniprot id: A0A098G3K2
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1212491:LFA RS04955
gene id: 1212491:LFA_RS04955
uniprot id: A0A098G246
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

1212491:LFA RS03495
gene id: 1212491:LFA_RS03495
uniprot id: A0A098G181
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1212491:LFA RS01310
gene id: 1212491:LFA_RS01310
uniprot id: A0A098G1B5
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1212491:LFA RS16190
gene id: 1212491:LFA_RS16190
uniprot id: A0A098GA39
names: Similarity
messages: Belongs to the UPF0229 family.

1212491:LFA RS05365
gene id: 1212491:LFA_RS05365
uniprot id: A0A098G3S9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS17330
gene id: 1212491:LFA_RS17330
uniprot id: A0A098GAN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1212491:LFA RS08205
gene id: 1212491:LFA_RS08205
uniprot id: A0A098G424
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1212491:LFA RS12715
gene id: 1212491:LFA_RS12715
uniprot id: A0A098G9J4
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1212491:LFA RS15565
gene id: 1212491:LFA_RS15565
uniprot id: A0A098GB84
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1212491:LFA RS09325
gene id: 1212491:LFA_RS09325
uniprot id: A0A098G652
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1212491:LFA RS04865
gene id: 1212491:LFA_RS04865
uniprot id: A0A098G221
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

1212491:LFA RS12620
gene id: 1212491:LFA_RS12620
uniprot id: A0A098G9I1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

1212491:LFA RS03735
gene id: 1212491:LFA_RS03735
uniprot id: A0A098G482
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1212491:LFA RS08190
gene id: 1212491:LFA_RS08190
uniprot id: A0A098G416
names: Similarity
messages: Belongs to the CvfB family.

1212491:LFA RS07370
gene id: 1212491:LFA_RS07370
uniprot id: A0A098G510
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1212491:LFA RS12505
gene id: 1212491:LFA_RS12505
uniprot id: A0A098G6M4
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS01095
gene id: 1212491:LFA_RS01095
uniprot id: A0A098FZR5
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1212491:LFA RS14360
gene id: 1212491:LFA_RS14360
uniprot id: A0A098G7Q2
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1212491:LFA RS00150
gene id: 1212491:LFA_RS00150
uniprot id: A0A098G0N4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

1212491:LFA RS07585
gene id: 1212491:LFA_RS07585
uniprot id: A0A098G3P5
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1212491:LFA RS14085
gene id: 1212491:LFA_RS14085
uniprot id: A0A098GAB3
names: Similarity
messages: Belongs to the UPF0047 family.

1212491:LFA RS00835
gene id: 1212491:LFA_RS00835
uniprot id: A0A098FZK7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1212491:LFA RS12405
gene id: 1212491:LFA_RS12405
uniprot id: A0A098G6L0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1212491:LFA RS05500
gene id: 1212491:LFA_RS05500
uniprot id: A0A098G2E7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

1212491:LFA RS17630
gene id: 1212491:LFA_RS17630
uniprot id: A0A098G9M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1212491:LFA RS07655
gene id: 1212491:LFA_RS07655
uniprot id: A0A098G3Q7
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS01875
gene id: 1212491:LFA_RS01875
uniprot id: A0A098G1N1
names: Similarity
messages: Belongs to the FeoA family.

1212491:LFA RS20080
gene id: 1212491:LFA_RS20080
uniprot id: A0A098G7J4
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS05710
gene id: 1212491:LFA_RS05710
uniprot id: A0A098G3Z1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

1212491:LFA RS04340
gene id: 1212491:LFA_RS04340
uniprot id: A0A098G1Q6
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

1212491:LFA RS17170
gene id: 1212491:LFA_RS17170
uniprot id: A0A098G974
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1212491:LFA RS08055
gene id: 1212491:LFA_RS08055
uniprot id: A0A098G5D8
names: Similarity
messages: Belongs to the peptidase S66 family.

1212491:LFA RS09110
gene id: 1212491:LFA_RS09110
uniprot id: A0A098G618
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1212491:LFA RS05695
gene id: 1212491:LFA_RS05695
uniprot id: A0A098G3Z0
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS07340
gene id: 1212491:LFA_RS07340
uniprot id: A0A098G6A8
names: Similarity
messages: Belongs to the YkuD family.

1212491:LFA RS02520
gene id: 1212491:LFA_RS02520
uniprot id: A0A098G0N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1212491:LFA RS18230
gene id: 1212491:LFA_RS18230
uniprot id: A0A098G9X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1212491:LFA RS04145
gene id: 1212491:LFA_RS04145
uniprot id: A0A098G312
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1212491:LFA RS03750
gene id: 1212491:LFA_RS03750
uniprot id: A0A098G1D1
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1212491:LFA RS02870
gene id: 1212491:LFA_RS02870
uniprot id: A0A098G3N9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1212491:LFA RS12850
gene id: 1212491:LFA_RS12850
uniprot id: A0A098G6S6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1212491:LFA RS15060
gene id: 1212491:LFA_RS15060
uniprot id: A0A098G827
names: Similarity
messages: Belongs to the group II decarboxylase family.

1212491:LFA RS16870
gene id: 1212491:LFA_RS16870
uniprot id: A0A098G945
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1212491:LFA RS09265
gene id: 1212491:LFA_RS09265
uniprot id: A0A098G643
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1212491:LFA RS11930
gene id: 1212491:LFA_RS11930
uniprot id: A0A098G7P8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1212491:LFA RS10040
gene id: 1212491:LFA_RS10040
uniprot id: A0A098G554
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1212491:LFA RS12035
gene id: 1212491:LFA_RS12035
uniprot id: A0A098G970
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS09230
gene id: 1212491:LFA_RS09230
uniprot id: A0A098G4N8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1212491:LFA RS12590
gene id: 1212491:LFA_RS12590
uniprot id: A0A098G6N1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1212491:LFA RS00515
gene id: 1212491:LFA_RS00515
uniprot id: A0A098FZF9
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

1212491:LFA RS04075
gene id: 1212491:LFA_RS04075
uniprot id: A0A098G4F6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1212491:LFA RS16290
gene id: 1212491:LFA_RS16290
uniprot id: A0A098G8Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane

1212491:LFA RS09200
gene id: 1212491:LFA_RS09200
uniprot id: A0A098G4L0
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

1212491:LFA RS03640
gene id: 1212491:LFA_RS03640
uniprot id: A0A098G1B1
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS01920
gene id: 1212491:LFA_RS01920
uniprot id: A0A098G097
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1212491:LFA RS16420
gene id: 1212491:LFA_RS16420
uniprot id: A0A098G8T0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1212491:LFA RS12020
gene id: 1212491:LFA_RS12020
uniprot id: A0A098G6D0
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1212491:LFA RS16015
gene id: 1212491:LFA_RS16015
uniprot id: A0A098GA03
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS11905
gene id: 1212491:LFA_RS11905
uniprot id: A0A098G7P3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS00185
gene id: 1212491:LFA_RS00185
uniprot id: A0A098G0N6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

1212491:LFA RS07930
gene id: 1212491:LFA_RS07930
uniprot id: A0A098G3W5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1212491:LFA RS14700
gene id: 1212491:LFA_RS14700
uniprot id: A0A098G9B2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1212491:LFA RS17825
gene id: 1212491:LFA_RS17825
uniprot id: A0A098G9R9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1212491:LFA RS14430
gene id: 1212491:LFA_RS14430
uniprot id: A0A098G7R6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

1212491:LFA RS18165
gene id: 1212491:LFA_RS18165
uniprot id: A0A098G9Z4
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS01880
gene id: 1212491:LFA_RS01880
uniprot id: A0A098G317
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1212491:LFA RS05380
gene id: 1212491:LFA_RS05380
uniprot id: A0A098G3Q6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1212491:LFA RS09455
gene id: 1212491:LFA_RS09455
uniprot id: A0A098G4R1
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1212491:LFA RS01485
gene id: 1212491:LFA_RS01485
uniprot id: A0A098G2U0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1212491:LFA RS14415
gene id: 1212491:LFA_RS14415
uniprot id: A0A098G917
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0761 family.
messages: Cell membrane
messages: Membrane

1212491:LFA RS00655
gene id: 1212491:LFA_RS00655
uniprot id: A0A098G2A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1212491:LFA RS15030
gene id: 1212491:LFA_RS15030
uniprot id: A0A098G819
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS10150
gene id: 1212491:LFA_RS10150
uniprot id: A0A098G6K9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1212491:LFA RS01155
gene id: 1212491:LFA_RS01155
uniprot id: A0A098G2M7
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

1212491:LFA RS16170
gene id: 1212491:LFA_RS16170
uniprot id: A0A098G8P6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS10825
gene id: 1212491:LFA_RS10825
uniprot id: A0A098G6Z0
names: Similarity
messages: Belongs to the XFP family.

1212491:LFA RS05665
gene id: 1212491:LFA_RS05665
uniprot id: A0A098G5C5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1212491:LFA RS05990
gene id: 1212491:LFA_RS05990
uniprot id: A0A098G2S7
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

1212491:LFA RS14220
gene id: 1212491:LFA_RS14220
uniprot id: A0A098G7M2
names: Similarity
messages: Belongs to the glutamine synthetase family.

1212491:LFA RS07030
gene id: 1212491:LFA_RS07030
uniprot id: A0A098G3D9
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1212491:LFA RS07115
gene id: 1212491:LFA_RS07115
uniprot id: A0A098G667
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

1212491:LFA RS05355
gene id: 1212491:LFA_RS05355
uniprot id: A0A098G3Q0
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

1212491:LFA RS05275
gene id: 1212491:LFA_RS05275
uniprot id: A0A098G2B1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

1212491:LFA RS03465
gene id: 1212491:LFA_RS03465
uniprot id: A0A098G175
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1212491:LFA RS07580
gene id: 1212491:LFA_RS07580
uniprot id: A0A098G3P2
names: Similarity
messages: Belongs to the GARS family.

1212491:LFA RS10435
gene id: 1212491:LFA_RS10435
uniprot id: A0A098G5E8
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.

1212491:LFA RS07820
gene id: 1212491:LFA_RS07820
uniprot id: A0A098G6N5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1212491:LFA RS08870
gene id: 1212491:LFA_RS08870
uniprot id: A0A098G5X2
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1212491:LFA RS00040
gene id: 1212491:LFA_RS00040
uniprot id: A0A098FZ52
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

1212491:LFA RS03825
gene id: 1212491:LFA_RS03825
uniprot id: A0A098G2U4
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1212491:LFA RS07830
gene id: 1212491:LFA_RS07830
uniprot id: A0A098G3T9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1212491:LFA RS12390
gene id: 1212491:LFA_RS12390
uniprot id: A0A098G7Z5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1212491:LFA RS07075
gene id: 1212491:LFA_RS07075
uniprot id: A0A098G3E0
names: Similarity
messages: Belongs to the threonine synthase family.

1212491:LFA RS03630
gene id: 1212491:LFA_RS03630
uniprot id: A0A098G2Q3
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1212491:LFA RS12105
gene id: 1212491:LFA_RS12105
uniprot id: A0A098G7T4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

1212491:LFA RS10110
gene id: 1212491:LFA_RS10110
uniprot id: A0A098G569
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1212491:LFA RS15375
gene id: 1212491:LFA_RS15375
uniprot id: A0A098G9L9
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1212491:LFA RS04500
gene id: 1212491:LFA_RS04500
uniprot id: A0A098G394
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1212491:LFA RS11385
gene id: 1212491:LFA_RS11385
uniprot id: A0A098G5U7
names: Similarity
messages: Belongs to the type III secretion exporter family.

1212491:LFA RS09115
gene id: 1212491:LFA_RS09115
uniprot id: A0A098G7D0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1212491:LFA RS12320
gene id: 1212491:LFA_RS12320
uniprot id: A0A098G6E9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1212491:LFA RS11770
gene id: 1212491:LFA_RS11770
uniprot id: A0A098G679
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1212491:LFA RS05110
gene id: 1212491:LFA_RS05110
uniprot id: A0A098G509
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1212491:LFA RS08940
gene id: 1212491:LFA_RS08940
uniprot id: A0A098G796
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

1212491:LFA RS17445
gene id: 1212491:LFA_RS17445
uniprot id: A0A098GAQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1212491:LFA RS10505
gene id: 1212491:LFA_RS10505
uniprot id: A0A098G5G3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1212491:LFA RS01935
gene id: 1212491:LFA_RS01935
uniprot id: A0A098G1N5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1212491:LFA RS02295
gene id: 1212491:LFA_RS02295
uniprot id: A0A098G1X5
names: Similarity
messages: Belongs to the transposase 8 family.

1212491:LFA RS14555
gene id: 1212491:LFA_RS14555
uniprot id: A0A098G983
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1212491:LFA RS12335
gene id: 1212491:LFA_RS12335
uniprot id: A0A098G7T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

1212491:LFA RS00860
gene id: 1212491:LFA_RS00860
uniprot id: A0A098G113
names: Similarity
messages: Belongs to the pyruvate kinase family.

1212491:LFA RS15535
gene id: 1212491:LFA_RS15535
uniprot id: A0A098G8B1
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1212491:LFA RS09660
gene id: 1212491:LFA_RS09660
uniprot id: A0A098G6B7
names: Similarity
messages: Belongs to the BolA/IbaG family.

1212491:LFA RS10325
gene id: 1212491:LFA_RS10325
uniprot id: A0A098G6P8
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS09540
gene id: 1212491:LFA_RS09540
uniprot id: A0A098G7K3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

1212491:LFA RS04305
gene id: 1212491:LFA_RS04305
uniprot id: A0A098G343
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1212491:LFA RS09170
gene id: 1212491:LFA_RS09170
uniprot id: A0A098G4M8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1212491:LFA RS07440
gene id: 1212491:LFA_RS07440
uniprot id: A0A098G3L5
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS08715
gene id: 1212491:LFA_RS08715
uniprot id: A0A098G4B2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1212491:LFA RS11590
gene id: 1212491:LFA_RS11590
uniprot id: A0A098G7E1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

1212491:LFA RS03945
gene id: 1212491:LFA_RS03945
uniprot id: A0A098G2X1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.

1212491:LFA RS14855
gene id: 1212491:LFA_RS14855
uniprot id: A0A098G800
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1212491:LFA RS11550
gene id: 1212491:LFA_RS11550
uniprot id: A0A098G5X9
names: Similarity
messages: Belongs to the peptidase M13 family.

1212491:LFA RS16070
gene id: 1212491:LFA_RS16070
uniprot id: A0A098G8M5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1212491:LFA RS01915
gene id: 1212491:LFA_RS01915
uniprot id: A0A098G069
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1212491:LFA RS11650
gene id: 1212491:LFA_RS11650
uniprot id: A0A098G5Z8
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS03860
gene id: 1212491:LFA_RS03860
uniprot id: A0A098G2V4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS11370
gene id: 1212491:LFA_RS11370
uniprot id: A0A098G8S6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1212491:LFA RS03925
gene id: 1212491:LFA_RS03925
uniprot id: A0A098G4C5
names: Similarity
messages: Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.

1212491:LFA RS05265
gene id: 1212491:LFA_RS05265
uniprot id: A0A098G3R3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1212491:LFA RS03975
gene id: 1212491:LFA_RS03975
uniprot id: A0A098G4D5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

1212491:LFA RS01275
gene id: 1212491:LFA_RS01275
uniprot id: A0A098FZV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.
messages: Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms.
messages: Cytoplasm
messages: Homodimer.

1212491:LFA RS07765
gene id: 1212491:LFA_RS07765
uniprot id: A0A098G3T0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1212491:LFA RS04740
gene id: 1212491:LFA_RS04740
uniprot id: A0A098G3E8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1212491:LFA RS12750
gene id: 1212491:LFA_RS12750
uniprot id: A0A098G6T0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1212491:LFA RS07650
gene id: 1212491:LFA_RS07650
uniprot id: A0A098G566
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1212491:LFA RS03350
gene id: 1212491:LFA_RS03350
uniprot id: A0A098G169
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

1212491:LFA RS14410
gene id: 1212491:LFA_RS14410
uniprot id: A0A098G7R3
names: Similarity
messages: Belongs to the WrbA family.

1212491:LFA RS10810
gene id: 1212491:LFA_RS10810
uniprot id: A0A098G5I5
names: Subcellular Location Annotation
names: Subunit
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane

1212491:LFA RS12385
gene id: 1212491:LFA_RS12385
uniprot id: A0A098G6G4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1212491:LFA RS06410
gene id: 1212491:LFA_RS06410
uniprot id: A0A098G2Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MutH family.
messages: Cytoplasm
messages: Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair.

1212491:LFA RS12460
gene id: 1212491:LFA_RS12460
uniprot id: A0A098G6I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1212491:LFA RS16660
gene id: 1212491:LFA_RS16660
uniprot id: A0A098G8X7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1212491:LFA RS13645
gene id: 1212491:LFA_RS13645
uniprot id: A0A098GA17
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS08840
gene id: 1212491:LFA_RS08840
uniprot id: A0A098G779
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1212491:LFA RS07990
gene id: 1212491:LFA_RS07990
uniprot id: A0A098G3X9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1212491:LFA RS16705
gene id: 1212491:LFA_RS16705
uniprot id: A0A098G907
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

1212491:LFA RS18185
gene id: 1212491:LFA_RS18185
uniprot id: A0A098GBB0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1212491:LFA RS13485
gene id: 1212491:LFA_RS13485
uniprot id: A0A098G8J3
names: Cofactor
messages: Binds 1 FMN per subunit.

1212491:LFA RS06185
gene id: 1212491:LFA_RS06185
uniprot id: A0A098G2W9
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1212491:LFA RS15665
gene id: 1212491:LFA_RS15665
uniprot id: A0A098G8D5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1212491:LFA RS12255
gene id: 1212491:LFA_RS12255
uniprot id: A0A098G9B9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1212491:LFA RS11645
gene id: 1212491:LFA_RS11645
uniprot id: A0A098G653
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1212491:LFA RS17410
gene id: 1212491:LFA_RS17410
uniprot id: A0A098GC90
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS14915
gene id: 1212491:LFA_RS14915
uniprot id: A0A098G9B0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1212491:LFA RS03405
gene id: 1212491:LFA_RS03405
uniprot id: A0A098G159
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1212491:LFA RS02550
gene id: 1212491:LFA_RS02550
uniprot id: A0A098G234
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS11915
gene id: 1212491:LFA_RS11915
uniprot id: A0A098G7K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

1212491:LFA RS12845
gene id: 1212491:LFA_RS12845
uniprot id: A0A098G6U8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1212491:LFA RS07600
gene id: 1212491:LFA_RS07600
uniprot id: A0A098G556
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1212491:LFA RS01995
gene id: 1212491:LFA_RS01995
uniprot id: A0A098G1Q1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.

1212491:LFA RS08985
gene id: 1212491:LFA_RS08985
uniprot id: A0A098G5Z0
names: Similarity
messages: Belongs to the MlaA family.

1212491:LFA RS02035
gene id: 1212491:LFA_RS02035
uniprot id: A0A098G1S0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1212491:LFA RS07260
gene id: 1212491:LFA_RS07260
uniprot id: A0A098G4V9
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1212491:LFA RS00510
gene id: 1212491:LFA_RS00510
uniprot id: A0A098G0W0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1212491:LFA RS03845
gene id: 1212491:LFA_RS03845
uniprot id: A0A098G1E9
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS13890
gene id: 1212491:LFA_RS13890
uniprot id: A0A098G8T8
names: Similarity
messages: Belongs to the UPF0145 family.

1212491:LFA RS01630
gene id: 1212491:LFA_RS01630
uniprot id: A0A098G1I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1212491:LFA RS07295
gene id: 1212491:LFA_RS07295
uniprot id: A0A098G4Z4
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1212491:LFA RS08925
gene id: 1212491:LFA_RS08925
uniprot id: A0A098G5Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1212491:LFA RS01170
gene id: 1212491:LFA_RS01170
uniprot id: A0A098FZT5
names: Function
names: Similarity
messages: Belongs to the chloramphenicol acetyltransferase family.
messages: This enzyme is an effector of chloramphenicol resistance in bacteria.

1212491:LFA RS09675
gene id: 1212491:LFA_RS09675
uniprot id: A0A098G6D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1212491:LFA RS08150
gene id: 1212491:LFA_RS08150
uniprot id: A0A098G6U6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1212491:LFA RS09255
gene id: 1212491:LFA_RS09255
uniprot id: A0A098G4P3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1212491:LFA RS17165
gene id: 1212491:LFA_RS17165
uniprot id: A0A098G9A6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS04665
gene id: 1212491:LFA_RS04665
uniprot id: A0A098G3B5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1212491:LFA RS17025
gene id: 1212491:LFA_RS17025
uniprot id: A0A098G946
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1212491:LFA RS17275
gene id: 1212491:LFA_RS17275
uniprot id: A0A098G994
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1212491:LFA RS06400
gene id: 1212491:LFA_RS06400
uniprot id: A0A098G5S3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

1212491:LFA RS12090
gene id: 1212491:LFA_RS12090
uniprot id: A0A098G7N4
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

1212491:LFA RS06650
gene id: 1212491:LFA_RS06650
uniprot id: A0A098G352
names: Similarity
messages: Belongs to the DEAD box helicase family.

1212491:LFA RS01985
gene id: 1212491:LFA_RS01985
uniprot id: A0A098G1Q9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1212491:LFA RS02875
gene id: 1212491:LFA_RS02875
uniprot id: A0A098G289
names: Similarity
messages: Belongs to the arginase family.

1212491:LFA RS10460
gene id: 1212491:LFA_RS10460
uniprot id: A0A098G5F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1212491:LFA RS10385
gene id: 1212491:LFA_RS10385
uniprot id: A0A098G5A7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1212491:LFA RS06680
gene id: 1212491:LFA_RS06680
uniprot id: A0A098G375
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS19070
gene id: 1212491:LFA_RS19070
uniprot id: A0A098GAF2
names: Similarity
messages: Belongs to the stealth family.

1212491:LFA RS12710
gene id: 1212491:LFA_RS12710
uniprot id: A0A098G844
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1212491:LFA RS07140
gene id: 1212491:LFA_RS07140
uniprot id: A0A098G672
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1212491:LFA RS17335
gene id: 1212491:LFA_RS17335
uniprot id: A0A098GC74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1212491:LFA RS14895
gene id: 1212491:LFA_RS14895
uniprot id: A0A098GAS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1212491:LFA RS08590
gene id: 1212491:LFA_RS08590
uniprot id: A0A098G490
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1212491:LFA RS14080
gene id: 1212491:LFA_RS14080
uniprot id: A0A098G8V0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

1212491:LFA RS01810
gene id: 1212491:LFA_RS01810
uniprot id: A0A098G1K8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

1212491:LFA RS16715
gene id: 1212491:LFA_RS16715
uniprot id: A0A098GAB5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1212491:LFA RS07410
gene id: 1212491:LFA_RS07410
uniprot id: A0A098G4Y9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1212491:LFA RS05505
gene id: 1212491:LFA_RS05505
uniprot id: A0A098G2H6
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

1212491:LFA RS01500
gene id: 1212491:LFA_RS01500
uniprot id: A0A098G005
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS17005
gene id: 1212491:LFA_RS17005
uniprot id: A0A098GAH0
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

1212491:LFA RS16985
gene id: 1212491:LFA_RS16985
uniprot id: A0A098GC02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1212491:LFA RS15455
gene id: 1212491:LFA_RS15455
uniprot id: A0A098G9P3
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1212491:LFA RS01570
gene id: 1212491:LFA_RS01570
uniprot id: A0A098G007
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1212491:LFA RS15570
gene id: 1212491:LFA_RS15570
uniprot id: A0A098G9S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1212491:LFA RS16590
gene id: 1212491:LFA_RS16590
uniprot id: A0A098G8W2
names: Similarity
messages: Belongs to the asparaginase 1 family.

1212491:LFA RS09185
gene id: 1212491:LFA_RS09185
uniprot id: A0A098G7D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP M family.
messages: Cell inner membrane
messages: Membrane

1212491:LFA RS13055
gene id: 1212491:LFA_RS13055
uniprot id: A0A098G8A8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1212491:LFA RS11720
gene id: 1212491:LFA_RS11720
uniprot id: A0A098G668
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1212491:LFA RS12795
gene id: 1212491:LFA_RS12795
uniprot id: A0A098G6T9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1212491:LFA RS05025
gene id: 1212491:LFA_RS05025
uniprot id: A0A098G254
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1212491:LFA RS12765
gene id: 1212491:LFA_RS12765
uniprot id: A0A098G9K2
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1212491:LFA RS16050
gene id: 1212491:LFA_RS16050
uniprot id: A0A098G8K3
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1212491:LFA RS16310
gene id: 1212491:LFA_RS16310
uniprot id: A0A098GA64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1212491:LFA RS00270
gene id: 1212491:LFA_RS00270
uniprot id: A0A098FZ92
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

1212491:LFA RS16430
gene id: 1212491:LFA_RS16430
uniprot id: A0A098GBP2
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS15560
gene id: 1212491:LFA_RS15560
uniprot id: A0A098G9Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

1212491:LFA RS16205
gene id: 1212491:LFA_RS16205
uniprot id: A0A098GBK1
names: Similarity
messages: Belongs to the DEAD box helicase family.

1212491:LFA RS00485
gene id: 1212491:LFA_RS00485
uniprot id: A0A098G273
names: Similarity
messages: Belongs to the UPF0178 family.

1212491:LFA RS10475
gene id: 1212491:LFA_RS10475
uniprot id: A0A098G897
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1212491:LFA RS06255
gene id: 1212491:LFA_RS06255
uniprot id: A0A098G2V7
names: Subcellular Location Annotation
messages: Cell inner membrane

1212491:LFA RS14275
gene id: 1212491:LFA_RS14275
uniprot id: A0A098GAF5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

1212491:LFA RS00065
gene id: 1212491:LFA_RS00065
uniprot id: A0A098FZ56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell.

1212491:LFA RS00190
gene id: 1212491:LFA_RS00190
uniprot id: A0A098G210
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1212491:LFA RS05160
gene id: 1212491:LFA_RS05160
uniprot id: A0A098G519
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1212491:LFA RS12855
gene id: 1212491:LFA_RS12855
uniprot id: A0A098G874
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1212491:LFA RS05175
gene id: 1212491:LFA_RS05175
uniprot id: A0A098G292
names: Subcellular Location Annotation
messages: Cytoplasm

1212491:LFA RS16850
gene id: 1212491:LFA_RS16850
uniprot id: A0A098G912
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1212491:LFA RS09530
gene id: 1212491:LFA_RS09530
uniprot id: A0A098G4S7
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1212491:LFA RS14215
gene id: 1212491:LFA_RS14215
uniprot id: A0A098G7L9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1212491:LFA RS15950
gene id: 1212491:LFA_RS15950
uniprot id: A0A098G9X0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1212491:LFA RS12510
gene id: 1212491:LFA_RS12510
uniprot id: A0A098G6J3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1212491:LFA RS13040
gene id: 1212491:LFA_RS13040
uniprot id: A0A098G6W0
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

1212491:LFA RS16760
gene id: 1212491:LFA_RS16760
uniprot id: A0A098G8Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1212491:LFA RS04490
gene id: 1212491:LFA_RS04490
uniprot id: A0A098G380
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

1212491:LFA RS16055
gene id: 1212491:LFA_RS16055
uniprot id: A0A098G9Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1212491:LFA RS09740
gene id: 1212491:LFA_RS09740
uniprot id: A0A098G4Z3
names: Similarity
messages: Belongs to the UPF0270 family.

1212491:LFA RS17900
gene id: 1212491:LFA_RS17900
uniprot id: A0A098GCK3
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1212491:LFA RS07285
gene id: 1212491:LFA_RS07285
uniprot id: A0A098G4W3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1212491:LFA RS15995
gene id: 1212491:LFA_RS15995
uniprot id: A0A098G8J2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1212491:LFA RS10010
gene id: 1212491:LFA_RS10010
uniprot id: A0A098G6I4
names: Similarity
messages: Belongs to the peptidase S8 family.

1212491:LFA RS10695
gene id: 1212491:LFA_RS10695
uniprot id: A0A098G8D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1212491:LFA RS11990
gene id: 1212491:LFA_RS11990
uniprot id: A0A098G7L5
names: Similarity
messages: Belongs to the peptidase S41A family.

1212491:LFA RS12585
gene id: 1212491:LFA_RS12585
uniprot id: A0A098G7Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1212491:LFA RS02075
gene id: 1212491:LFA_RS02075
uniprot id: A0A098G098
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1212491:LFA RS05285
gene id: 1212491:LFA_RS05285
uniprot id: A0A098G545
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

1212491:LFA RS06460
gene id: 1212491:LFA_RS06460
uniprot id: A0A098G4E5
names: Caution
names: Similarity
messages: Belongs to the UPF0391 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS06525
gene id: 1212491:LFA_RS06525
uniprot id: A0A098G4F8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1212491:LFA RS08790
gene id: 1212491:LFA_RS08790
uniprot id: A0A098G5V1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1212491:LFA RS02635
gene id: 1212491:LFA_RS02635
uniprot id: A0A098G255
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS15025
gene id: 1212491:LFA_RS15025
uniprot id: A0A098G9G9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS15660
gene id: 1212491:LFA_RS15660
uniprot id: A0A098G8D9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1212491:LFA RS10105
gene id: 1212491:LFA_RS10105
uniprot id: A0A098G6K4
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS00870
gene id: 1212491:LFA_RS00870
uniprot id: A0A098G115
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1212491:LFA RS07500
gene id: 1212491:LFA_RS07500
uniprot id: A0A098G536
names: Similarity
messages: Belongs to the TPP enzyme family.

1212491:LFA RS03215
gene id: 1212491:LFA_RS03215
uniprot id: A0A098G2G5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1212491:LFA RS17245
gene id: 1212491:LFA_RS17245
uniprot id: A0A098G989
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1212491:LFA RS04840
gene id: 1212491:LFA_RS04840
uniprot id: A0A098G216
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1212491:LFA RS16675
gene id: 1212491:LFA_RS16675
uniprot id: A0A098GAE3
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

1212491:LFA RS05115
gene id: 1212491:LFA_RS05115
uniprot id: A0A098G3N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1212491:LFA RS03500
gene id: 1212491:LFA_RS03500
uniprot id: A0A098G2M4
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1212491:LFA RS14850
gene id: 1212491:LFA_RS14850
uniprot id: A0A098G9E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

1212491:LFA RS02855
gene id: 1212491:LFA_RS02855
uniprot id: A0A098G0Q6
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

1212491:LFA RS13265
gene id: 1212491:LFA_RS13265
uniprot id: A0A098G8E7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1212491:LFA RS07705
gene id: 1212491:LFA_RS07705
uniprot id: A0A098G3R8
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1212491:LFA RS03695
gene id: 1212491:LFA_RS03695
uniprot id: A0A098G471
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1212491:LFA RS12365
gene id: 1212491:LFA_RS12365
uniprot id: A0A098G6F9
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS08025
gene id: 1212491:LFA_RS08025
uniprot id: A0A098G6S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

1212491:LFA RS05730
gene id: 1212491:LFA_RS05730
uniprot id: A0A098G2M2
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

1212491:LFA RS01785
gene id: 1212491:LFA_RS01785
uniprot id: A0A098G1K3
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

1212491:LFA RS16100
gene id: 1212491:LFA_RS16100
uniprot id: A0A098G8N1
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1212491:LFA RS16465
gene id: 1212491:LFA_RS16465
uniprot id: A0A098G8V7
names: Similarity
messages: Belongs to the RNase T2 family.

1212491:LFA RS18390
gene id: 1212491:LFA_RS18390
uniprot id: A0A098GA48
names: Similarity
messages: Belongs to the antirestriction protein family.

1212491:LFA RS16110
gene id: 1212491:LFA_RS16110
uniprot id: A0A098GA01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1212491:LFA RS09095
gene id: 1212491:LFA_RS09095
uniprot id: A0A098G7C5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1212491:LFA RS04375
gene id: 1212491:LFA_RS04375
uniprot id: A0A098G4L7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1212491:LFA RS15870
gene id: 1212491:LFA_RS15870
uniprot id: A0A098G9X4
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1212491:LFA RS17420
gene id: 1212491:LFA_RS17420
uniprot id: A0A098GAQ3
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS15510
gene id: 1212491:LFA_RS15510
uniprot id: A0A098G8A6
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1212491:LFA RS07760
gene id: 1212491:LFA_RS07760
uniprot id: A0A098G582
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS07675
gene id: 1212491:LFA_RS07675
uniprot id: A0A098G3R2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1212491:LFA RS11600
gene id: 1212491:LFA_RS11600
uniprot id: A0A098G5Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1212491:LFA RS07970
gene id: 1212491:LFA_RS07970
uniprot id: A0A098G3X4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

1212491:LFA RS10070
gene id: 1212491:LFA_RS10070
uniprot id: A0A098G6L3
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1212491:LFA RS03960
gene id: 1212491:LFA_RS03960
uniprot id: A0A098G1J2
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

1212491:LFA RS17450
gene id: 1212491:LFA_RS17450
uniprot id: A0A098GC98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1212491:LFA RS13880
gene id: 1212491:LFA_RS13880
uniprot id: A0A098G8Q7
names: Similarity
messages: Belongs to the group II decarboxylase family.

1212491:LFA RS06380
gene id: 1212491:LFA_RS06380
uniprot id: A0A098G4E3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
messages: Cytoplasm
messages: Monomer.
messages: The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.

1212491:LFA RS05130
gene id: 1212491:LFA_RS05130
uniprot id: A0A098G3K8
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1212491:LFA RS09245
gene id: 1212491:LFA_RS09245
uniprot id: A0A098G7E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Membrane

1212491:LFA RS07310
gene id: 1212491:LFA_RS07310
uniprot id: A0A098G4W8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1212491:LFA RS13815
gene id: 1212491:LFA_RS13815
uniprot id: A0A098GA52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

1212491:LFA RS11955
gene id: 1212491:LFA_RS11955
uniprot id: A0A098G7Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1212491:LFA RS00875
gene id: 1212491:LFA_RS00875
uniprot id: A0A098FZL4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1212491:LFA RS06830
gene id: 1212491:LFA_RS06830
uniprot id: A0A098G3A2
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1212491:LFA RS03240
gene id: 1212491:LFA_RS03240
uniprot id: A0A098G2H0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

1212491:LFA RS09665
gene id: 1212491:LFA_RS09665
uniprot id: A0A098G4X8
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS04165
gene id: 1212491:LFA_RS04165
uniprot id: A0A098G318
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1212491:LFA RS15495
gene id: 1212491:LFA_RS15495
uniprot id: A0A098GB68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1212491:LFA RS17645
gene id: 1212491:LFA_RS17645
uniprot id: A0A098GCE6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1212491:LFA RS05270
gene id: 1212491:LFA_RS05270
uniprot id: A0A098G2A7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1212491:LFA RS04140
gene id: 1212491:LFA_RS04140
uniprot id: A0A098G1K9
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1212491:LFA RS03605
gene id: 1212491:LFA_RS03605
uniprot id: A0A098G2P8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1212491:LFA RS04335
gene id: 1212491:LFA_RS04335
uniprot id: A0A098G355
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1212491:LFA RS03730
gene id: 1212491:LFA_RS03730
uniprot id: A0A098G1C7
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1212491:LFA RS12065
gene id: 1212491:LFA_RS12065
uniprot id: A0A098G7N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1212491:LFA RS08735
gene id: 1212491:LFA_RS08735
uniprot id: A0A098G4B7
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1212491:LFA RS20345
gene id: 1212491:LFA_RS20345
uniprot id: A0A098G8H2
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS15705
gene id: 1212491:LFA_RS15705
uniprot id: A0A098G9U3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1212491:LFA RS10815
gene id: 1212491:LFA_RS10815
uniprot id: A0A098G702
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.

1212491:LFA RS13030
gene id: 1212491:LFA_RS13030
uniprot id: A0A098G8A3
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

1212491:LFA RS15670
gene id: 1212491:LFA_RS15670
uniprot id: A0A098G9S2
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1212491:LFA RS06125
gene id: 1212491:LFA_RS06125
uniprot id: A0A098G480
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1212491:LFA RS10200
gene id: 1212491:LFA_RS10200
uniprot id: A0A098G7Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).

1212491:LFA RS07125
gene id: 1212491:LFA_RS07125
uniprot id: A0A098G3F1
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS11500
gene id: 1212491:LFA_RS11500
uniprot id: A0A098G622
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1212491:LFA RS02770
gene id: 1212491:LFA_RS02770
uniprot id: A0A098G286
names: Similarity
messages: Belongs to the pirin family.

1212491:LFA RS07880
gene id: 1212491:LFA_RS07880
uniprot id: A0A098G3V5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1212491:LFA RS11815
gene id: 1212491:LFA_RS11815
uniprot id: A0A098G7I2
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1212491:LFA RS15585
gene id: 1212491:LFA_RS15585
uniprot id: A0A098G9Q9
names: Similarity
messages: Belongs to the UPF0111 family.

1212491:LFA RS09335
gene id: 1212491:LFA_RS09335
uniprot id: A0A098G4N7
names: Similarity
messages: Belongs to the FliN/MopA/SpaO family.

1212491:LFA RS01565
gene id: 1212491:LFA_RS01565
uniprot id: A0A098G1G0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1212491:LFA RS04365
gene id: 1212491:LFA_RS04365
uniprot id: A0A098G1R3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1212491:LFA RS09860
gene id: 1212491:LFA_RS09860
uniprot id: A0A098G7R7
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1212491:LFA RS09320
gene id: 1212491:LFA_RS09320
uniprot id: A0A098G7G2
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1212491:LFA RS10115
gene id: 1212491:LFA_RS10115
uniprot id: A0A098G560
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1212491:LFA RS17075
gene id: 1212491:LFA_RS17075
uniprot id: A0A098GAI5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1212491:LFA RS04120
gene id: 1212491:LFA_RS04120
uniprot id: A0A098G307
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

1212491:LFA RS08470
gene id: 1212491:LFA_RS08470
uniprot id: A0A098G468
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

1212491:LFA RS04065
gene id: 1212491:LFA_RS04065
uniprot id: A0A098G1J4
names: Similarity
messages: Belongs to the peptidase S49 family.

1212491:LFA RS14025
gene id: 1212491:LFA_RS14025
uniprot id: A0A098G7H9
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1212491:LFA RS05250
gene id: 1212491:LFA_RS05250
uniprot id: A0A098G2A6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1212491:LFA RS19785
gene id: 1212491:LFA_RS19785
uniprot id: A0A098G315
names: Similarity
messages: Belongs to the transposase 7 family.

1212491:LFA RS16645
gene id: 1212491:LFA_RS16645
uniprot id: A0A098GBT4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1212491:LFA RS03525
gene id: 1212491:LFA_RS03525
uniprot id: A0A098G2M8
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1212491:LFA RS04010
gene id: 1212491:LFA_RS04010
uniprot id: A0A098G1K2
names: Similarity
messages: Belongs to the BolA/IbaG family.

1212491:LFA RS05595
gene id: 1212491:LFA_RS05595
uniprot id: A0A098G2G6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1212491:LFA RS12275
gene id: 1212491:LFA_RS12275
uniprot id: A0A098G7X0
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1212491:LFA RS02350
gene id: 1212491:LFA_RS02350
uniprot id: A0A098G3B8
names: Similarity
messages: Belongs to the UPF0270 family.

1212491:LFA RS10780
gene id: 1212491:LFA_RS10780
uniprot id: A0A098G5M1
names: Function
names: Similarity
messages: Belongs to the ATPase gamma chain family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1212491:LFA RS17050
gene id: 1212491:LFA_RS17050
uniprot id: A0A098G950
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

1212491:LFA RS01430
gene id: 1212491:LFA_RS01430
uniprot id: A0A098G2T0
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

1212491:LFA RS07175
gene id: 1212491:LFA_RS07175
uniprot id: A0A098G3G2
names: Similarity
messages: Belongs to the YfgM family.

1212491:LFA RS04685
gene id: 1212491:LFA_RS04685
uniprot id: A0A098G4S6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1212491:LFA RS08765
gene id: 1212491:LFA_RS08765
uniprot id: A0A098G5U4
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1212491:LFA RS11790
gene id: 1212491:LFA_RS11790
uniprot id: A0A098G7H7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1212491:LFA RS01600
gene id: 1212491:LFA_RS01600
uniprot id: A0A098G028
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1212491:LFA RS07840
gene id: 1212491:LFA_RS07840
uniprot id: A0A098G591
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1212491:LFA RS12345
gene id: 1212491:LFA_RS12345
uniprot id: A0A098G7Y7
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS19110
gene id: 1212491:LFA_RS19110
uniprot id: A0A098GBC8
names: Similarity
messages: Belongs to the transposase 7 family.

1212491:LFA RS12770
gene id: 1212491:LFA_RS12770
uniprot id: A0A098G857
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1212491:LFA RS06925
gene id: 1212491:LFA_RS06925
uniprot id: A0A098G3A9
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1212491:LFA RS00705
gene id: 1212491:LFA_RS00705
uniprot id: A0A098G0Y4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1212491:LFA RS17640
gene id: 1212491:LFA_RS17640
uniprot id: A0A098GAZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase B chain family.
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Membrane

1212491:LFA RS12465
gene id: 1212491:LFA_RS12465
uniprot id: A0A098G805
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1212491:LFA RS05640
gene id: 1212491:LFA_RS05640
uniprot id: A0A098G5C0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1212491:LFA RS07160
gene id: 1212491:LFA_RS07160
uniprot id: A0A098G4T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1212491:LFA RS03880
gene id: 1212491:LFA_RS03880
uniprot id: A0A098G4B3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1212491:LFA RS13130
gene id: 1212491:LFA_RS13130
uniprot id: A0A098G8B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1212491:LFA RS16040
gene id: 1212491:LFA_RS16040
uniprot id: A0A098GA08
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1212491:LFA RS09525
gene id: 1212491:LFA_RS09525
uniprot id: A0A098G4V1
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1212491:LFA RS05530
gene id: 1212491:LFA_RS05530
uniprot id: A0A098G3V9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1212491:LFA RS05170
gene id: 1212491:LFA_RS05170
uniprot id: A0A098G285
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

1212491:LFA RS02475
gene id: 1212491:LFA_RS02475
uniprot id: A0A098G0M4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

1212491:LFA RS11125
gene id: 1212491:LFA_RS11125
uniprot id: A0A098G772
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1212491:LFA RS14055
gene id: 1212491:LFA_RS14055
uniprot id: A0A098G7I4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1212491:LFA RS10170
gene id: 1212491:LFA_RS10170
uniprot id: A0A098G7Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

1212491:LFA RS14685
gene id: 1212491:LFA_RS14685
uniprot id: A0A098G7W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1212491:LFA RS02485
gene id: 1212491:LFA_RS02485
uniprot id: A0A098G3F0
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1212491:LFA RS12310
gene id: 1212491:LFA_RS12310
uniprot id: A0A098G7T0
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

1212491:LFA RS16210
gene id: 1212491:LFA_RS16210
uniprot id: A0A098GA45
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

1212491:LFA RS09990
gene id: 1212491:LFA_RS09990
uniprot id: A0A098G544
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1212491:LFA RS12985
gene id: 1212491:LFA_RS12985
uniprot id: A0A098G889
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1212491:LFA RS01150
gene id: 1212491:LFA_RS01150
uniprot id: A0A098G179
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1212491:LFA RS11950
gene id: 1212491:LFA_RS11950
uniprot id: A0A098G666
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1212491:LFA RS06135
gene id: 1212491:LFA_RS06135
uniprot id: A0A098G491
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

1212491:LFA RS13725
gene id: 1212491:LFA_RS13725
uniprot id: A0A098G7B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1212491:LFA RS12280
gene id: 1212491:LFA_RS12280
uniprot id: A0A098G9C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

1212491:LFA RS05125
gene id: 1212491:LFA_RS05125
uniprot id: A0A098G282
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.

1212491:LFA RS06100
gene id: 1212491:LFA_RS06100
uniprot id: A0A098G475
names: Similarity
messages: Belongs to the citrate synthase family.

1212491:LFA RS05370
gene id: 1212491:LFA_RS05370
uniprot id: A0A098G2C6
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.

1212491:LFA RS06315
gene id: 1212491:LFA_RS06315
uniprot id: A0A098G4C0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1212491:LFA RS06290
gene id: 1212491:LFA_RS06290
uniprot id: A0A098G4B4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1212491:LFA RS09820
gene id: 1212491:LFA_RS09820
uniprot id: A0A098G512
names: Function
messages: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.

1212491:LFA RS07905
gene id: 1212491:LFA_RS07905
uniprot id: A0A098G3W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1212491:LFA RS15625
gene id: 1212491:LFA_RS15625
uniprot id: A0A098G8D0
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1212491:LFA RS08825
gene id: 1212491:LFA_RS08825
uniprot id: A0A098G4G0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1212491:LFA RS09535
gene id: 1212491:LFA_RS09535
uniprot id: A0A098G699
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1212491:LFA RS10100
gene id: 1212491:LFA_RS10100
uniprot id: A0A098G7W6
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS03565
gene id: 1212491:LFA_RS03565
uniprot id: A0A098G1A6
names: Similarity
messages: Belongs to the asparagine synthetase family.

1212491:LFA RS15715
gene id: 1212491:LFA_RS15715
uniprot id: A0A098G8E4
names: Similarity
messages: Belongs to the YjdM family.

1212491:LFA RS01305
gene id: 1212491:LFA_RS01305
uniprot id: A0A098FZW8
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

1212491:LFA RS12600
gene id: 1212491:LFA_RS12600
uniprot id: A0A098G9H8
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

1212491:LFA RS17535
gene id: 1212491:LFA_RS17535
uniprot id: A0A098GAX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1212491:LFA RS00055
gene id: 1212491:LFA_RS00055
uniprot id: A0A098G1Y3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1212491:LFA RS12015
gene id: 1212491:LFA_RS12015
uniprot id: A0A098G7M0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1212491:LFA RS09930
gene id: 1212491:LFA_RS09930
uniprot id: A0A098G7T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

1212491:LFA RS17855
gene id: 1212491:LFA_RS17855
uniprot id: A0A098GCJ1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1212491:LFA RS04115
gene id: 1212491:LFA_RS04115
uniprot id: A0A098G1K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

1212491:LFA RS02610
gene id: 1212491:LFA_RS02610
uniprot id: A0A098G0Q4
names: Similarity
messages: Belongs to the glycosyl hydrolase 81 family.

1212491:LFA RS08990
gene id: 1212491:LFA_RS08990
uniprot id: A0A098G7A6
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1212491:LFA RS10145
gene id: 1212491:LFA_RS10145
uniprot id: A0A098G7X5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

1212491:LFA RS06095
gene id: 1212491:LFA_RS06095
uniprot id: A0A098G2S1
names: Similarity
messages: Belongs to the FGGY kinase family.

1212491:LFA RS10515
gene id: 1212491:LFA_RS10515
uniprot id: A0A098G6T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1212491:LFA RS00095
gene id: 1212491:LFA_RS00095
uniprot id: A0A098G1Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

1212491:LFA RS01410
gene id: 1212491:LFA_RS01410
uniprot id: A0A098G1C9
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

1212491:LFA RS14425
gene id: 1212491:LFA_RS14425
uniprot id: A0A098G957
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1212491:LFA RS09940
gene id: 1212491:LFA_RS09940
uniprot id: A0A098G534
names: Similarity
messages: Belongs to the RutC family.

1212491:LFA RS02450
gene id: 1212491:LFA_RS02450
uniprot id: A0A098G0H0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1212491:LFA RS01970
gene id: 1212491:LFA_RS01970
uniprot id: A0A098G1Q3
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

1212491:LFA RS07400
gene id: 1212491:LFA_RS07400
uniprot id: A0A098G3K7
names: Similarity
messages: Belongs to the YkuD family.

1212491:LFA RS16320
gene id: 1212491:LFA_RS16320
uniprot id: A0A098G8R2
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1212491:LFA RS05440
gene id: 1212491:LFA_RS05440
uniprot id: A0A098G587
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1212491:LFA RS00645
gene id: 1212491:LFA_RS00645
uniprot id: A0A098FZH2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS18180
gene id: 1212491:LFA_RS18180
uniprot id: A0A098GCS0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1212491:LFA RS03795
gene id: 1212491:LFA_RS03795
uniprot id: A0A098G1E1
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1212491:LFA RS01625
gene id: 1212491:LFA_RS01625
uniprot id: A0A098G033
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS08670
gene id: 1212491:LFA_RS08670
uniprot id: A0A098G5S4
names: Similarity
messages: Belongs to the peptidase U62 family.

1212491:LFA RS05280
gene id: 1212491:LFA_RS05280
uniprot id: A0A098G3N6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1212491:LFA RS16200
gene id: 1212491:LFA_RS16200
uniprot id: A0A098GA19
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS07825
gene id: 1212491:LFA_RS07825
uniprot id: A0A098G590
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

1212491:LFA RS12760
gene id: 1212491:LFA_RS12760
uniprot id: A0A098G852
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1212491:LFA RS14335
gene id: 1212491:LFA_RS14335
uniprot id: A0A098G7P7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1212491:LFA RS10035
gene id: 1212491:LFA_RS10035
uniprot id: A0A098G6I9
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1212491:LFA RS11575
gene id: 1212491:LFA_RS11575
uniprot id: A0A098G5Y4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1212491:LFA RS11780
gene id: 1212491:LFA_RS11780
uniprot id: A0A098G7L7
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

1212491:LFA RS05870
gene id: 1212491:LFA_RS05870
uniprot id: A0A098G2M0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1212491:LFA RS05585
gene id: 1212491:LFA_RS05585
uniprot id: A0A098G5B1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS06280
gene id: 1212491:LFA_RS06280
uniprot id: A0A098G2W2
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1212491:LFA RS09305
gene id: 1212491:LFA_RS09305
uniprot id: A0A098G4Q4
names: Subcellular Location Annotation
messages: Cytoplasm

1212491:LFA RS12925
gene id: 1212491:LFA_RS12925
uniprot id: A0A098G879
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1212491:LFA RS04515
gene id: 1212491:LFA_RS04515
uniprot id: A0A098G386
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1212491:LFA RS01925
gene id: 1212491:LFA_RS01925
uniprot id: A0A098G1P3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1212491:LFA RS07095
gene id: 1212491:LFA_RS07095
uniprot id: A0A098G4V4
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

1212491:LFA RS03425
gene id: 1212491:LFA_RS03425
uniprot id: A0A098G164
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Catalyzes the synthesis of activated sulfate.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1212491:LFA RS02510
gene id: 1212491:LFA_RS02510
uniprot id: A0A098G3F7
names: Similarity
messages: Belongs to the YkuD family.

1212491:LFA RS02505
gene id: 1212491:LFA_RS02505
uniprot id: A0A098G223
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1212491:LFA RS10030
gene id: 1212491:LFA_RS10030
uniprot id: A0A098G7V2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS10050
gene id: 1212491:LFA_RS10050
uniprot id: A0A098G6L2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1212491:LFA RS05855
gene id: 1212491:LFA_RS05855
uniprot id: A0A098G422
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS07745
gene id: 1212491:LFA_RS07745
uniprot id: A0A098G3S4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinylarginine dihydrolase family.
messages: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
messages: Homodimer.

1212491:LFA RS06980
gene id: 1212491:LFA_RS06980
uniprot id: A0A098G3D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

1212491:LFA RS00575
gene id: 1212491:LFA_RS00575
uniprot id: A0A098G0W6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MdcC family.
messages: Covalently binds the prosthetic group of malonate decarboxylase.
messages: Cytoplasm
messages: Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism.

1212491:LFA RS01845
gene id: 1212491:LFA_RS01845
uniprot id: A0A098G082
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1212491:LFA RS13925
gene id: 1212491:LFA_RS13925
uniprot id: A0A098GA78
names: Similarity
messages: Belongs to the class-D beta-lactamase family.

1212491:LFA RS15245
gene id: 1212491:LFA_RS15245
uniprot id: A0A098G9K3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1212491:LFA RS16685
gene id: 1212491:LFA_RS16685
uniprot id: A0A098G8Y1
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1212491:LFA RS17530
gene id: 1212491:LFA_RS17530
uniprot id: A0A098GCB8
names: Similarity
messages: Belongs to the FrmR/RcnR family.

1212491:LFA RS07845
gene id: 1212491:LFA_RS07845
uniprot id: A0A098G6P1
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

1212491:LFA RS07070
gene id: 1212491:LFA_RS07070
uniprot id: A0A098G4U8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1212491:LFA RS01315
gene id: 1212491:LFA_RS01315
uniprot id: A0A098G2R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1212491:LFA RS03890
gene id: 1212491:LFA_RS03890
uniprot id: A0A098G1H7
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

1212491:LFA RS12180
gene id: 1212491:LFA_RS12180
uniprot id: A0A098G7V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbI/VirB10 family.
messages: Membrane

1212491:LFA RS00720
gene id: 1212491:LFA_RS00720
uniprot id: A0A098G0Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

1212491:LFA RS08315
gene id: 1212491:LFA_RS08315
uniprot id: A0A098G438
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1212491:LFA RS11765
gene id: 1212491:LFA_RS11765
uniprot id: A0A098G7H2
names: Similarity
messages: Belongs to the YkuD family.

1212491:LFA RS08650
gene id: 1212491:LFA_RS08650
uniprot id: A0A098G741
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1212491:LFA RS05555
gene id: 1212491:LFA_RS05555
uniprot id: A0A098G3W3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

1212491:LFA RS16060
gene id: 1212491:LFA_RS16060
uniprot id: A0A098GBH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1212491:LFA RS13870
gene id: 1212491:LFA_RS13870
uniprot id: A0A098G7E3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1212491:LFA RS01800
gene id: 1212491:LFA_RS01800
uniprot id: A0A098G1L6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1212491:LFA RS12250
gene id: 1212491:LFA_RS12250
uniprot id: A0A098G7W4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1212491:LFA RS04760
gene id: 1212491:LFA_RS04760
uniprot id: A0A098G4U0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS07545
gene id: 1212491:LFA_RS07545
uniprot id: A0A098G6E8
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS05890
gene id: 1212491:LFA_RS05890
uniprot id: A0A098G2Q7
names: Similarity
messages: Belongs to the YkuD family.

1212491:LFA RS17290
gene id: 1212491:LFA_RS17290
uniprot id: A0A098GAS0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS18425
gene id: 1212491:LFA_RS18425
uniprot id: A0A098GBG2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1212491:LFA RS17655
gene id: 1212491:LFA_RS17655
uniprot id: A0A098G9M7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1212491:LFA RS08015
gene id: 1212491:LFA_RS08015
uniprot id: A0A098G3Y2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1212491:LFA RS16585
gene id: 1212491:LFA_RS16585
uniprot id: A0A098G8Y2
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

1212491:LFA RS04645
gene id: 1212491:LFA_RS04645
uniprot id: A0A098G4R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1212491:LFA RS05195
gene id: 1212491:LFA_RS05195
uniprot id: A0A098G291
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

1212491:LFA RS03785
gene id: 1212491:LFA_RS03785
uniprot id: A0A098G2T9
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1212491:LFA RS12400
gene id: 1212491:LFA_RS12400
uniprot id: A0A098G7U8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1212491:LFA RS00420
gene id: 1212491:LFA_RS00420
uniprot id: A0A098G0U5
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

1212491:LFA RS17635
gene id: 1212491:LFA_RS17635
uniprot id: A0A098G9J6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1212491:LFA RS12700
gene id: 1212491:LFA_RS12700
uniprot id: A0A098G843
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1212491:LFA RS12830
gene id: 1212491:LFA_RS12830
uniprot id: A0A098G869
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1212491:LFA RS10060
gene id: 1212491:LFA_RS10060
uniprot id: A0A098G559
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

1212491:LFA RS09100
gene id: 1212491:LFA_RS09100
uniprot id: A0A098G616
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1212491:LFA RS01605
gene id: 1212491:LFA_RS01605
uniprot id: A0A098G1H6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1212491:LFA RS08720
gene id: 1212491:LFA_RS08720
uniprot id: A0A098G5T4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1212491:LFA RS06795
gene id: 1212491:LFA_RS06795
uniprot id: A0A098G4L6
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1212491:LFA RS16470
gene id: 1212491:LFA_RS16470
uniprot id: A0A098GA68
names: Subcellular Location Annotation
messages: Cytoplasm

1212491:LFA RS07560
gene id: 1212491:LFA_RS07560
uniprot id: A0A098G3P0
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

1212491:LFA RS14675
gene id: 1212491:LFA_RS14675
uniprot id: A0A098GAN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

1212491:LFA RS12125
gene id: 1212491:LFA_RS12125
uniprot id: A0A098G6A5
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1212491:LFA RS17665
gene id: 1212491:LFA_RS17665
uniprot id: A0A098GB00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1212491:LFA RS04815
gene id: 1212491:LFA_RS04815
uniprot id: A0A098G212
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

1212491:LFA RS09965
gene id: 1212491:LFA_RS09965
uniprot id: A0A098G538
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1212491:LFA RS12945
gene id: 1212491:LFA_RS12945
uniprot id: A0A098G6U0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1212491:LFA RS07570
gene id: 1212491:LFA_RS07570
uniprot id: A0A098G6F3
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1212491:LFA RS05970
gene id: 1212491:LFA_RS05970
uniprot id: A0A098G444
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1212491:LFA RS00275
gene id: 1212491:LFA_RS00275
uniprot id: A0A098G0Q7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

1212491:LFA RS18190
gene id: 1212491:LFA_RS18190
uniprot id: A0A098G9Z9
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS00525
gene id: 1212491:LFA_RS00525
uniprot id: A0A098G0W1
names: Similarity
messages: Belongs to the peptidase C59 family.

1212491:LFA RS09670
gene id: 1212491:LFA_RS09670
uniprot id: A0A098G4W1
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

1212491:LFA RS12000
gene id: 1212491:LFA_RS12000
uniprot id: A0A098G677
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1212491:LFA RS05540
gene id: 1212491:LFA_RS05540
uniprot id: A0A098G3V8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

1212491:LFA RS10275
gene id: 1212491:LFA_RS10275
uniprot id: A0A098G6P0
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS08965
gene id: 1212491:LFA_RS08965
uniprot id: A0A098G7A1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1212491:LFA RS01790
gene id: 1212491:LFA_RS01790
uniprot id: A0A098G047
names: Similarity
messages: Belongs to the peptidase M16 family.

1212491:LFA RS01285
gene id: 1212491:LFA_RS01285
uniprot id: A0A098G1B0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1212491:LFA RS19020
gene id: 1212491:LFA_RS19020
uniprot id: A0A098G8D4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1212491:LFA RS10055
gene id: 1212491:LFA_RS10055
uniprot id: A0A098G6J4
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

1212491:LFA RS07165
gene id: 1212491:LFA_RS07165
uniprot id: A0A098G676
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1212491:LFA RS09180
gene id: 1212491:LFA_RS09180
uniprot id: A0A098G628
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP L family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

1212491:LFA RS00015
gene id: 1212491:LFA_RS00015
uniprot id: A0A098G0K3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1212491:LFA RS11880
gene id: 1212491:LFA_RS11880
uniprot id: A0A098G7N7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1212491:LFA RS04390
gene id: 1212491:LFA_RS04390
uniprot id: A0A098G1R8
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS15370
gene id: 1212491:LFA_RS15370
uniprot id: A0A098G875
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1212491:LFA RS05245
gene id: 1212491:LFA_RS05245
uniprot id: A0A098G2A2
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1212491:LFA RS16045
gene id: 1212491:LFA_RS16045
uniprot id: A0A098G8L9
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1212491:LFA RS09520
gene id: 1212491:LFA_RS09520
uniprot id: A0A098G687
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

1212491:LFA RS00440
gene id: 1212491:LFA_RS00440
uniprot id: A0A098G263
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1212491:LFA RS05260
gene id: 1212491:LFA_RS05260
uniprot id: A0A098G539
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1212491:LFA RS05230
gene id: 1212491:LFA_RS05230
uniprot id: A0A098G3M6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

1212491:LFA RS00315
gene id: 1212491:LFA_RS00315
uniprot id: A0A098FZA4
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Homotetramer.

1212491:LFA RS07130
gene id: 1212491:LFA_RS07130
uniprot id: A0A098G3F8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1212491:LFA RS13620
gene id: 1212491:LFA_RS13620
uniprot id: A0A098G8L3
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS01815
gene id: 1212491:LFA_RS01815
uniprot id: A0A098G052
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

1212491:LFA RS11505
gene id: 1212491:LFA_RS11505
uniprot id: A0A098G5W9
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.
messages: Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids.

1212491:LFA RS17815
gene id: 1212491:LFA_RS17815
uniprot id: A0A098GCI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1212491:LFA RS12880
gene id: 1212491:LFA_RS12880
uniprot id: A0A098G6T2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1212491:LFA RS04080
gene id: 1212491:LFA_RS04080
uniprot id: A0A098G2Z6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1212491:LFA RS04435
gene id: 1212491:LFA_RS04435
uniprot id: A0A098G1T3
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1212491:LFA RS00885
gene id: 1212491:LFA_RS00885
uniprot id: A0A098G118
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1212491:LFA RS04265
gene id: 1212491:LFA_RS04265
uniprot id: A0A098G4J5
names: Function
names: Similarity
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.

1212491:LFA RS15390
gene id: 1212491:LFA_RS15390
uniprot id: A0A098G881
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose.
messages: Cell inner membrane
messages: Membrane

1212491:LFA RS06385
gene id: 1212491:LFA_RS06385
uniprot id: A0A098G2Y3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS12395
gene id: 1212491:LFA_RS12395
uniprot id: A0A098G9E7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1212491:LFA RS13455
gene id: 1212491:LFA_RS13455
uniprot id: A0A098G749
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1212491:LFA RS12535
gene id: 1212491:LFA_RS12535
uniprot id: A0A098G6J8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

1212491:LFA RS09885
gene id: 1212491:LFA_RS09885
uniprot id: A0A098G6G3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1212491:LFA RS06845
gene id: 1212491:LFA_RS06845
uniprot id: A0A098G4Q1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1212491:LFA RS00405
gene id: 1212491:LFA_RS00405
uniprot id: A0A098FZC3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1212491:LFA RS17515
gene id: 1212491:LFA_RS17515
uniprot id: A0A098G9H4
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

1212491:LFA RS04035
gene id: 1212491:LFA_RS04035
uniprot id: A0A098G1K7
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS09280
gene id: 1212491:LFA_RS09280
uniprot id: A0A098G4P9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1212491:LFA RS06085
gene id: 1212491:LFA_RS06085
uniprot id: A0A098G5L1
names: Similarity
messages: Belongs to the thioredoxin family.

1212491:LFA RS12685
gene id: 1212491:LFA_RS12685
uniprot id: A0A098G6P2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1212491:LFA RS05750
gene id: 1212491:LFA_RS05750
uniprot id: A0A098G2J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

1212491:LFA RS03585
gene id: 1212491:LFA_RS03585
uniprot id: A0A098G1B2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

1212491:LFA RS06090
gene id: 1212491:LFA_RS06090
uniprot id: A0A098G479
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1212491:LFA RS17440
gene id: 1212491:LFA_RS17440
uniprot id: A0A098G9C6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1212491:LFA RS04380
gene id: 1212491:LFA_RS04380
uniprot id: A0A098G365
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1212491:LFA RS02640
gene id: 1212491:LFA_RS02640
uniprot id: A0A098G3I7
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1212491:LFA RS03050
gene id: 1212491:LFA_RS03050
uniprot id: A0A098G3S7
names: Similarity
messages: Belongs to the peptidase S66 family.

1212491:LFA RS02605
gene id: 1212491:LFA_RS02605
uniprot id: A0A098G0K4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AcsB/BcsB family.
messages: Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP).
messages: Cell inner membrane
messages: Tightly associated with the cellulose synthase catalytic subunit.

1212491:LFA RS14350
gene id: 1212491:LFA_RS14350
uniprot id: A0A098G940
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS12270
gene id: 1212491:LFA_RS12270
uniprot id: A0A098G6D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1212491:LFA RS12755
gene id: 1212491:LFA_RS12755
uniprot id: A0A098G6Q5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1212491:LFA RS04610
gene id: 1212491:LFA_RS04610
uniprot id: A0A098G1W7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1212491:LFA RS09780
gene id: 1212491:LFA_RS09780
uniprot id: A0A098G502
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1212491:LFA RS12670
gene id: 1212491:LFA_RS12670
uniprot id: A0A098G9I5
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS15985
gene id: 1212491:LFA_RS15985
uniprot id: A0A098G9Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1212491:LFA RS16625
gene id: 1212491:LFA_RS16625
uniprot id: A0A098GAD2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1212491:LFA RS04985
gene id: 1212491:LFA_RS04985
uniprot id: A0A098G3H8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS16830
gene id: 1212491:LFA_RS16830
uniprot id: A0A098GAD8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1212491:LFA RS05480
gene id: 1212491:LFA_RS05480
uniprot id: A0A098G2G9
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1212491:LFA RS04545
gene id: 1212491:LFA_RS04545
uniprot id: A0A098G4Q0
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1212491:LFA RS13935
gene id: 1212491:LFA_RS13935
uniprot id: A0A098G7F8
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1212491:LFA RS15330
gene id: 1212491:LFA_RS15330
uniprot id: A0A098G9L8
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1212491:LFA RS17455
gene id: 1212491:LFA_RS17455
uniprot id: A0A098GAV5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1212491:LFA RS15590
gene id: 1212491:LFA_RS15590
uniprot id: A0A098GB88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1212491:LFA RS17510
gene id: 1212491:LFA_RS17510
uniprot id: A0A098GAW7
names: Similarity
messages: Belongs to the XFP family.

1212491:LFA RS05840
gene id: 1212491:LFA_RS05840
uniprot id: A0A098G5F8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

1212491:LFA RS06805
gene id: 1212491:LFA_RS06805
uniprot id: A0A098G4P0
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1212491:LFA RS16630
gene id: 1212491:LFA_RS16630
uniprot id: A0A098G8Z2
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS07150
gene id: 1212491:LFA_RS07150
uniprot id: A0A098G3F5
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1212491:LFA RS15945
gene id: 1212491:LFA_RS15945
uniprot id: A0A098G8I0
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS03430
gene id: 1212491:LFA_RS03430
uniprot id: A0A098G2K9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1212491:LFA RS07120
gene id: 1212491:LFA_RS07120
uniprot id: A0A098G4V8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

1212491:LFA RS12045
gene id: 1212491:LFA_RS12045
uniprot id: A0A098G6D5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1212491:LFA RS10790
gene id: 1212491:LFA_RS10790
uniprot id: A0A098G6Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase B chain family.
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Membrane

1212491:LFA RS14660
gene id: 1212491:LFA_RS14660
uniprot id: A0A098G7W2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

1212491:LFA RS03820
gene id: 1212491:LFA_RS03820
uniprot id: A0A098G1E5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1212491:LFA RS05215
gene id: 1212491:LFA_RS05215
uniprot id: A0A098G3Q2
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

1212491:LFA RS16875
gene id: 1212491:LFA_RS16875
uniprot id: A0A098G918
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1212491:LFA RS04255
gene id: 1212491:LFA_RS04255
uniprot id: A0A098G1N4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1212491:LFA RS08750
gene id: 1212491:LFA_RS08750
uniprot id: A0A098G5U3
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1212491:LFA RS02025
gene id: 1212491:LFA_RS02025
uniprot id: A0A098G091
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS04620
gene id: 1212491:LFA_RS04620
uniprot id: A0A098G4R3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1212491:LFA RS12675
gene id: 1212491:LFA_RS12675
uniprot id: A0A098G838
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1212491:LFA RS15225
gene id: 1212491:LFA_RS15225
uniprot id: A0A098G850
names: Similarity
messages: Belongs to the Dps family.

1212491:LFA RS04455
gene id: 1212491:LFA_RS04455
uniprot id: A0A098G1T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

1212491:LFA RS12060
gene id: 1212491:LFA_RS12060
uniprot id: A0A098G975
names: Subcellular Location Annotation
messages: Cytoplasm

1212491:LFA RS15880
gene id: 1212491:LFA_RS15880
uniprot id: A0A098G8G9
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS08945
gene id: 1212491:LFA_RS08945
uniprot id: A0A098G5Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

1212491:LFA RS08110
gene id: 1212491:LFA_RS08110
uniprot id: A0A098G5E9
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS04325
gene id: 1212491:LFA_RS04325
uniprot id: A0A098G348
names: Similarity
messages: Belongs to the peptidase S1C family.

1212491:LFA RS07250
gene id: 1212491:LFA_RS07250
uniprot id: A0A098G3H6
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1212491:LFA RS05235
gene id: 1212491:LFA_RS05235
uniprot id: A0A098G535
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1212491:LFA RS17685
gene id: 1212491:LFA_RS17685
uniprot id: A0A098G9K5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1212491:LFA RS03755
gene id: 1212491:LFA_RS03755
uniprot id: A0A098G2S9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS05930
gene id: 1212491:LFA_RS05930
uniprot id: A0A098G442
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1212491:LFA RS08860
gene id: 1212491:LFA_RS08860
uniprot id: A0A098G5W7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1212491:LFA RS07525
gene id: 1212491:LFA_RS07525
uniprot id: A0A098G542
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS04150
gene id: 1212491:LFA_RS04150
uniprot id: A0A098G4H1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1212491:LFA RS00865
gene id: 1212491:LFA_RS00865
uniprot id: A0A098G2G2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1212491:LFA RS10425
gene id: 1212491:LFA_RS10425
uniprot id: A0A098G888
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS02000
gene id: 1212491:LFA_RS02000
uniprot id: A0A098G086
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1212491:LFA RS00140
gene id: 1212491:LFA_RS00140
uniprot id: A0A098G0M6
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS01575
gene id: 1212491:LFA_RS01575
uniprot id: A0A098G022
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1212491:LFA RS00145
gene id: 1212491:LFA_RS00145
uniprot id: A0A098G200
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS00535
gene id: 1212491:LFA_RS00535
uniprot id: A0A098G0W4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1212491:LFA RS07920
gene id: 1212491:LFA_RS07920
uniprot id: A0A098G5A8
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS14400
gene id: 1212491:LFA_RS14400
uniprot id: A0A098G952
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1212491:LFA RS17435
gene id: 1212491:LFA_RS17435
uniprot id: A0A098G9G1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS10830
gene id: 1212491:LFA_RS10830
uniprot id: A0A098G5N2
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

1212491:LFA RS06730
gene id: 1212491:LFA_RS06730
uniprot id: A0A098G385
names: Cofactor
messages: Binds 1 Ca(2+) ion per subunit.

1212491:LFA RS02790
gene id: 1212491:LFA_RS02790
uniprot id: A0A098G0U4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1212491:LFA RS07200
gene id: 1212491:LFA_RS07200
uniprot id: A0A098G3G6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1212491:LFA RS03615
gene id: 1212491:LFA_RS03615
uniprot id: A0A098G1A7
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS03740
gene id: 1212491:LFA_RS03740
uniprot id: A0A098G2S8
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1212491:LFA RS00020
gene id: 1212491:LFA_RS00020
uniprot id: A0A098FZ46
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1212491:LFA RS05820
gene id: 1212491:LFA_RS05820
uniprot id: A0A098G415
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1212491:LFA RS05020
gene id: 1212491:LFA_RS05020
uniprot id: A0A098G3L3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1212491:LFA RS10730
gene id: 1212491:LFA_RS10730
uniprot id: A0A098G5L0
names: Similarity
messages: Belongs to the CFA/CMAS family.

1212491:LFA RS02465
gene id: 1212491:LFA_RS02465
uniprot id: A0A098G3E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Membrane

1212491:LFA RS12680
gene id: 1212491:LFA_RS12680
uniprot id: A0A098G6R5
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1212491:LFA RS14925
gene id: 1212491:LFA_RS14925
uniprot id: A0A098G9F7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1212491:LFA RS14635
gene id: 1212491:LFA_RS14635
uniprot id: A0A098G998
names: Similarity
messages: Belongs to the nitroreductase family. HadB/RutE subfamily.

1212491:LFA RS17740
gene id: 1212491:LFA_RS17740
uniprot id: A0A098GB15
names: Function
messages: Mediates the mercuric-dependent induction of mercury resistance operon. In the absence of mercury MerR represses transcription by binding tightly to the mer operator region; when mercury is present the dimeric complex binds a single ion and becomes a potent transcriptional activator, while remaining bound to the mer site.

1212491:LFA RS17255
gene id: 1212491:LFA_RS17255
uniprot id: A0A098GAL8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

1212491:LFA RS00755
gene id: 1212491:LFA_RS00755
uniprot id: A0A098G0Z3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1212491:LFA RS03200
gene id: 1212491:LFA_RS03200
uniprot id: A0A098G2G4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

1212491:LFA RS08955
gene id: 1212491:LFA_RS08955
uniprot id: A0A098G4G3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1212491:LFA RS08570
gene id: 1212491:LFA_RS08570
uniprot id: A0A098G5Q2
names: Subcellular Location Annotation
messages: Cytoplasm

1212491:LFA RS02965
gene id: 1212491:LFA_RS02965
uniprot id: A0A098G2A8
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1212491:LFA RS09240
gene id: 1212491:LFA_RS09240
uniprot id: A0A098G639
names: Similarity
messages: Belongs to the type III secretion exporter family.

1212491:LFA RS01465
gene id: 1212491:LFA_RS01465
uniprot id: A0A098FZY9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

1212491:LFA RS07385
gene id: 1212491:LFA_RS07385
uniprot id: A0A098G4Y5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1212491:LFA RS15970
gene id: 1212491:LFA_RS15970
uniprot id: A0A098G8I5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1212491:LFA RS17015
gene id: 1212491:LFA_RS17015
uniprot id: A0A098GAL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1212491:LFA RS05140
gene id: 1212491:LFA_RS05140
uniprot id: A0A098G3N8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1212491:LFA RS03910
gene id: 1212491:LFA_RS03910
uniprot id: A0A098G1I2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS01850
gene id: 1212491:LFA_RS01850
uniprot id: A0A098G1M6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1212491:LFA RS04810
gene id: 1212491:LFA_RS04810
uniprot id: A0A098G3G5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1212491:LFA RS00505
gene id: 1212491:LFA_RS00505
uniprot id: A0A098G278
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

1212491:LFA RS14175
gene id: 1212491:LFA_RS14175
uniprot id: A0A098GAD4
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1212491:LFA RS16180
gene id: 1212491:LFA_RS16180
uniprot id: A0A098GA14
names: Similarity
messages: Belongs to the peptidase M1 family.

1212491:LFA RS00660
gene id: 1212491:LFA_RS00660
uniprot id: A0A098G0X9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1212491:LFA RS05740
gene id: 1212491:LFA_RS05740
uniprot id: A0A098G5E0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1212491:LFA RS16350
gene id: 1212491:LFA_RS16350
uniprot id: A0A098GA46
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS04605
gene id: 1212491:LFA_RS04605
uniprot id: A0A098G1W8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

1212491:LFA RS15445
gene id: 1212491:LFA_RS15445
uniprot id: A0A098G9N3
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1212491:LFA RS14540
gene id: 1212491:LFA_RS14540
uniprot id: A0A098G7U0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS02495
gene id: 1212491:LFA_RS02495
uniprot id: A0A098G0H9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

1212491:LFA RS12450
gene id: 1212491:LFA_RS12450
uniprot id: A0A098G7V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1212491:LFA RS00500
gene id: 1212491:LFA_RS00500
uniprot id: A0A098G0V7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1212491:LFA RS08610
gene id: 1212491:LFA_RS08610
uniprot id: A0A098G4B6
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS16710
gene id: 1212491:LFA_RS16710
uniprot id: A0A098G8Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1212491:LFA RS17340
gene id: 1212491:LFA_RS17340
uniprot id: A0A098GAT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1212491:LFA RS15710
gene id: 1212491:LFA_RS15710
uniprot id: A0A098G8F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

1212491:LFA RS02705
gene id: 1212491:LFA_RS02705
uniprot id: A0A098G3K4
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS02810
gene id: 1212491:LFA_RS02810
uniprot id: A0A098G0P6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1212491:LFA RS01300
gene id: 1212491:LFA_RS01300
uniprot id: A0A098FZW2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

1212491:LFA RS00225
gene id: 1212491:LFA_RS00225
uniprot id: A0A098FZ90
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1212491:LFA RS04735
gene id: 1212491:LFA_RS04735
uniprot id: A0A098G4T5
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS05360
gene id: 1212491:LFA_RS05360
uniprot id: A0A098G558
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

1212491:LFA RS12120
gene id: 1212491:LFA_RS12120
uniprot id: A0A098G6F1
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1212491:LFA RS05240
gene id: 1212491:LFA_RS05240
uniprot id: A0A098G3Q8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1212491:LFA RS04820
gene id: 1212491:LFA_RS04820
uniprot id: A0A098G215
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

1212491:LFA RS09165
gene id: 1212491:LFA_RS09165
uniprot id: A0A098G625
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1212491:LFA RS09460
gene id: 1212491:LFA_RS09460
uniprot id: A0A098G684
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

1212491:LFA RS05680
gene id: 1212491:LFA_RS05680
uniprot id: A0A098G2L2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1212491:LFA RS04990
gene id: 1212491:LFA_RS04990
uniprot id: A0A098G4Y7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

1212491:LFA RS01395
gene id: 1212491:LFA_RS01395
uniprot id: A0A098FZY4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1212491:LFA RS07345
gene id: 1212491:LFA_RS07345
uniprot id: A0A098G505
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Cell inner membrane
messages: Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP.
messages: Membrane

1212491:LFA RS00165
gene id: 1212491:LFA_RS00165
uniprot id: A0A098G205
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1212491:LFA RS05620
gene id: 1212491:LFA_RS05620
uniprot id: A0A098G2H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane
messages: Membrane

1212491:LFA RS11180
gene id: 1212491:LFA_RS11180
uniprot id: A0A098G8N8
names: Cofactor
messages: Binds 1 FMN per subunit.

1212491:LFA RS06530
gene id: 1212491:LFA_RS06530
uniprot id: A0A098G5V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1212491:LFA RS05700
gene id: 1212491:LFA_RS05700
uniprot id: A0A098G2I4
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1212491:LFA RS08725
gene id: 1212491:LFA_RS08725
uniprot id: A0A098G755
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1212491:LFA RS11585
gene id: 1212491:LFA_RS11585
uniprot id: A0A098G8X4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1212491:LFA RS05775
gene id: 1212491:LFA_RS05775
uniprot id: A0A098G2K0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

1212491:LFA RS12775
gene id: 1212491:LFA_RS12775
uniprot id: A0A098G6T3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1212491:LFA RS10570
gene id: 1212491:LFA_RS10570
uniprot id: A0A098G6U9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1212491:LFA RS12790
gene id: 1212491:LFA_RS12790
uniprot id: A0A098G860
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1212491:LFA RS04175
gene id: 1212491:LFA_RS04175
uniprot id: A0A098G1N7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1212491:LFA RS15530
gene id: 1212491:LFA_RS15530
uniprot id: A0A098G8B2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

1212491:LFA RS16525
gene id: 1212491:LFA_RS16525
uniprot id: A0A098GBR1
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1212491:LFA RS13850
gene id: 1212491:LFA_RS13850
uniprot id: A0A098G7D5
names: Similarity
messages: Belongs to the LOG family.

1212491:LFA RS13740
gene id: 1212491:LFA_RS13740
uniprot id: A0A098GA37
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1212491:LFA RS17345
gene id: 1212491:LFA_RS17345
uniprot id: A0A098G9E4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1212491:LFA RS02425
gene id: 1212491:LFA_RS02425
uniprot id: A0A098G0G5
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1212491:LFA RS11980
gene id: 1212491:LFA_RS11980
uniprot id: A0A098G7Q8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1212491:LFA RS03365
gene id: 1212491:LFA_RS03365
uniprot id: A0A098G3Z8
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS05545
gene id: 1212491:LFA_RS05545
uniprot id: A0A098G2F7
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1212491:LFA RS11595
gene id: 1212491:LFA_RS11595
uniprot id: A0A098G642
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1212491:LFA RS14365
gene id: 1212491:LFA_RS14365
uniprot id: A0A098G908
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0187 family.
messages: Membrane

1212491:LFA RS16385
gene id: 1212491:LFA_RS16385
uniprot id: A0A098GA80
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1212491:LFA RS02685
gene id: 1212491:LFA_RS02685
uniprot id: A0A098G3J8
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family.

1212491:LFA RS08835
gene id: 1212491:LFA_RS08835
uniprot id: A0A098G5W2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1212491:LFA RS05135
gene id: 1212491:LFA_RS05135
uniprot id: A0A098G514
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1212491:LFA RS11560
gene id: 1212491:LFA_RS11560
uniprot id: A0A098G8W9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1212491:LFA RS09680
gene id: 1212491:LFA_RS09680
uniprot id: A0A098G7N3
names: Similarity
messages: Belongs to the UPF0434 family.

1212491:LFA RS08815
gene id: 1212491:LFA_RS08815
uniprot id: A0A098G774
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS04860
gene id: 1212491:LFA_RS04860
uniprot id: A0A098G3H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cytoplasm

1212491:LFA RS13695
gene id: 1212491:LFA_RS13695
uniprot id: A0A098G8P2
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

1212491:LFA RS04720
gene id: 1212491:LFA_RS04720
uniprot id: A0A098G1Z2
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS06790
gene id: 1212491:LFA_RS06790
uniprot id: A0A098G395
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

1212491:LFA RS05720
gene id: 1212491:LFA_RS05720
uniprot id: A0A098G3Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1212491:LFA RS05950
gene id: 1212491:LFA_RS05950
uniprot id: A0A098G5I4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1212491:LFA RS08620
gene id: 1212491:LFA_RS08620
uniprot id: A0A098G5R3
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS05985
gene id: 1212491:LFA_RS05985
uniprot id: A0A098G2P6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1212491:LFA RS17230
gene id: 1212491:LFA_RS17230
uniprot id: A0A098GC53
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1212491:LFA RS16885
gene id: 1212491:LFA_RS16885
uniprot id: A0A098GBY4
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1212491:LFA RS12810
gene id: 1212491:LFA_RS12810
uniprot id: A0A098G9K9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1212491:LFA RS16155
gene id: 1212491:LFA_RS16155
uniprot id: A0A098G8M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1212491:LFA RS06540
gene id: 1212491:LFA_RS06540
uniprot id: A0A098G319
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

1212491:LFA RS17080
gene id: 1212491:LFA_RS17080
uniprot id: A0A098GC23
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS00085
gene id: 1212491:LFA_RS00085
uniprot id: A0A098G0L8
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

1212491:LFA RS00060
gene id: 1212491:LFA_RS00060
uniprot id: A0A098G0L3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1212491:LFA RS09285
gene id: 1212491:LFA_RS09285
uniprot id: A0A098G4M6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1212491:LFA RS07110
gene id: 1212491:LFA_RS07110
uniprot id: A0A098G4S9
names: Similarity
messages: Belongs to the citrate synthase family.

1212491:LFA RS18430
gene id: 1212491:LFA_RS18430
uniprot id: A0A098GA58
names: Similarity
messages: Belongs to the pirin family.

1212491:LFA RS12115
gene id: 1212491:LFA_RS12115
uniprot id: A0A098G7N9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1212491:LFA RS05075
gene id: 1212491:LFA_RS05075
uniprot id: A0A098G264
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1212491:LFA RS16020
gene id: 1212491:LFA_RS16020
uniprot id: A0A098G8L4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1212491:LFA RS10775
gene id: 1212491:LFA_RS10775
uniprot id: A0A098G6Y0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1212491:LFA RS03635
gene id: 1212491:LFA_RS03635
uniprot id: A0A098G1C2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family.
messages: Cell outer membrane
messages: Essential virulence factor associated with macrophage infectivity. Exhibits PPIase activity.
messages: Membrane

1212491:LFA RS10860
gene id: 1212491:LFA_RS10860
uniprot id: A0A098G5J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1212491:LFA RS09865
gene id: 1212491:LFA_RS09865
uniprot id: A0A098G6F7
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1212491:LFA RS06145
gene id: 1212491:LFA_RS06145
uniprot id: A0A098G2W0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1212491:LFA RS05645
gene id: 1212491:LFA_RS05645
uniprot id: A0A098G3Y0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1212491:LFA RS04910
gene id: 1212491:LFA_RS04910
uniprot id: A0A098G3G4
names: Similarity
messages: Belongs to the UPF0234 family.

1212491:LFA RS09155
gene id: 1212491:LFA_RS09155
uniprot id: A0A098G623
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1212491:LFA RS01795
gene id: 1212491:LFA_RS01795
uniprot id: A0A098G070
names: Similarity
messages: Belongs to the peptidase M16 family.

1212491:LFA RS07135
gene id: 1212491:LFA_RS07135
uniprot id: A0A098G4T4
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

1212491:LFA RS17225
gene id: 1212491:LFA_RS17225
uniprot id: A0A098GAL4
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1212491:LFA RS12705
gene id: 1212491:LFA_RS12705
uniprot id: A0A098G6P7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1212491:LFA RS15050
gene id: 1212491:LFA_RS15050
uniprot id: A0A098G9H2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1212491:LFA RS10610
gene id: 1212491:LFA_RS10610
uniprot id: A0A098G5I3
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1212491:LFA RS10795
gene id: 1212491:LFA_RS10795
uniprot id: A0A098G8F6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1212491:LFA RS05685
gene id: 1212491:LFA_RS05685
uniprot id: A0A098G3Y6
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

1212491:LFA RS06800
gene id: 1212491:LFA_RS06800
uniprot id: A0A098G605
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1212491:LFA RS08810
gene id: 1212491:LFA_RS08810
uniprot id: A0A098G5V6
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1212491:LFA RS14450
gene id: 1212491:LFA_RS14450
uniprot id: A0A098G962
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS10045
gene id: 1212491:LFA_RS10045
uniprot id: A0A098G543
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1212491:LFA RS03955
gene id: 1212491:LFA_RS03955
uniprot id: A0A098G2X3
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS06250
gene id: 1212491:LFA_RS06250
uniprot id: A0A098G4B5
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1212491:LFA RS09975
gene id: 1212491:LFA_RS09975
uniprot id: A0A098G6J7
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS10140
gene id: 1212491:LFA_RS10140
uniprot id: A0A098G6M3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS07605
gene id: 1212491:LFA_RS07605
uniprot id: A0A098G3P8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1212491:LFA RS09715
gene id: 1212491:LFA_RS09715
uniprot id: A0A098G4Y8
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

1212491:LFA RS01590
gene id: 1212491:LFA_RS01590
uniprot id: A0A098G1G4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1212491:LFA RS12725
gene id: 1212491:LFA_RS12725
uniprot id: A0A098G6S5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1212491:LFA RS02070
gene id: 1212491:LFA_RS02070
uniprot id: A0A098G1R7
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS05960
gene id: 1212491:LFA_RS05960
uniprot id: A0A098G2N9
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1212491:LFA RS03870
gene id: 1212491:LFA_RS03870
uniprot id: A0A098G1F2
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS05635
gene id: 1212491:LFA_RS05635
uniprot id: A0A098G3X6
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1212491:LFA RS05760
gene id: 1212491:LFA_RS05760
uniprot id: A0A098G401
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

1212491:LFA RS02480
gene id: 1212491:LFA_RS02480
uniprot id: A0A098G218
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1212491:LFA RS03905
gene id: 1212491:LFA_RS03905
uniprot id: A0A098G2W5
names: Similarity
messages: Belongs to the TrpC family.

1212491:LFA RS15900
gene id: 1212491:LFA_RS15900
uniprot id: A0A098G8I6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1212491:LFA RS07080
gene id: 1212491:LFA_RS07080
uniprot id: A0A098G3E9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1212491:LFA RS03335
gene id: 1212491:LFA_RS03335
uniprot id: A0A098G2J0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1212491:LFA RS01945
gene id: 1212491:LFA_RS01945
uniprot id: A0A098G0A2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS06275
gene id: 1212491:LFA_RS06275
uniprot id: A0A098G4C1
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

1212491:LFA RS13065
gene id: 1212491:LFA_RS13065
uniprot id: A0A098G6W7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

1212491:LFA RS01595
gene id: 1212491:LFA_RS01595
uniprot id: A0A098G012
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1212491:LFA RS10545
gene id: 1212491:LFA_RS10545
uniprot id: A0A098G6U4
names: Similarity
messages: Belongs to the GSP E family.

1212491:LFA RS07940
gene id: 1212491:LFA_RS07940
uniprot id: A0A098G6Q7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1212491:LFA RS07395
gene id: 1212491:LFA_RS07395
uniprot id: A0A098G516
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS10600
gene id: 1212491:LFA_RS10600
uniprot id: A0A098G8B8
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1212491:LFA RS17400
gene id: 1212491:LFA_RS17400
uniprot id: A0A098G9B6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1212491:LFA RS00790
gene id: 1212491:LFA_RS00790
uniprot id: A0A098FZJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

1212491:LFA RS03855
gene id: 1212491:LFA_RS03855
uniprot id: A0A098G4A7
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

1212491:LFA RS07620
gene id: 1212491:LFA_RS07620
uniprot id: A0A098G6G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Membrane

1212491:LFA RS10455
gene id: 1212491:LFA_RS10455
uniprot id: A0A098G6R7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1212491:LFA RS05845
gene id: 1212491:LFA_RS05845
uniprot id: A0A098G2L5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1212491:LFA RS10205
gene id: 1212491:LFA_RS10205
uniprot id: A0A098G6L7
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

1212491:LFA RS03580
gene id: 1212491:LFA_RS03580
uniprot id: A0A098G2P3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1212491:LFA RS00540
gene id: 1212491:LFA_RS00540
uniprot id: A0A098FZG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1212491:LFA RS17700
gene id: 1212491:LFA_RS17700
uniprot id: A0A098GB06
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS04370
gene id: 1212491:LFA_RS04370
uniprot id: A0A098G359
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1212491:LFA RS09370
gene id: 1212491:LFA_RS09370
uniprot id: A0A098G7H1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1212491:LFA RS04510
gene id: 1212491:LFA_RS04510
uniprot id: A0A098G1U5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1212491:LFA RS16565
gene id: 1212491:LFA_RS16565
uniprot id: A0A098G8V6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1212491:LFA RS14355
gene id: 1212491:LFA_RS14355
uniprot id: A0A098G7Q1
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1212491:LFA RS15300
gene id: 1212491:LFA_RS15300
uniprot id: A0A098GB33
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1212491:LFA RS09950
gene id: 1212491:LFA_RS09950
uniprot id: A0A098G6J2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1212491:LFA RS09980
gene id: 1212491:LFA_RS09980
uniprot id: A0A098G7U2
names: Similarity
messages: Belongs to the GSP E family.

1212491:LFA RS17065
gene id: 1212491:LFA_RS17065
uniprot id: A0A098G987
names: Similarity
messages: Belongs to the thioredoxin family.

1212491:LFA RS05835
gene id: 1212491:LFA_RS05835
uniprot id: A0A098G417
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1212491:LFA RS05515
gene id: 1212491:LFA_RS05515
uniprot id: A0A098G3V1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1212491:LFA RS11615
gene id: 1212491:LFA_RS11615
uniprot id: A0A098G7E6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1212491:LFA RS02040
gene id: 1212491:LFA_RS02040
uniprot id: A0A098G351
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1212491:LFA RS09560
gene id: 1212491:LFA_RS09560
uniprot id: A0A098G6A4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1212491:LFA RS01280
gene id: 1212491:LFA_RS01280
uniprot id: A0A098FZW3
names: Similarity
messages: Belongs to the UPF0145 family.

1212491:LFA RS16955
gene id: 1212491:LFA_RS16955
uniprot id: A0A098GAG0
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1212491:LFA RS06645
gene id: 1212491:LFA_RS06645
uniprot id: A0A098G4K9
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS05850
gene id: 1212491:LFA_RS05850
uniprot id: A0A098G2P7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1212491:LFA RS06875
gene id: 1212491:LFA_RS06875
uniprot id: A0A098G4Q6
names: Similarity
messages: Belongs to the transposase 7 family.

1212491:LFA RS00795
gene id: 1212491:LFA_RS00795
uniprot id: A0A098G2F0
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

1212491:LFA RS02650
gene id: 1212491:LFA_RS02650
uniprot id: A0A098G0L4
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1212491:LFA RS05945
gene id: 1212491:LFA_RS05945
uniprot id: A0A098G440
names: Similarity
messages: Belongs to the fabD family.

1212491:LFA RS12805
gene id: 1212491:LFA_RS12805
uniprot id: A0A098G864
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1212491:LFA RS01345
gene id: 1212491:LFA_RS01345
uniprot id: A0A098G1B8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

1212491:LFA RS12695
gene id: 1212491:LFA_RS12695
uniprot id: A0A098G9I9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1212491:LFA RS12285
gene id: 1212491:LFA_RS12285
uniprot id: A0A098G7S5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

1212491:LFA RS05770
gene id: 1212491:LFA_RS05770
uniprot id: A0A098G404
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

1212491:LFA RS15875
gene id: 1212491:LFA_RS15875
uniprot id: A0A098G8I1
names: Similarity
messages: Belongs to the peptidase S24 family.

1212491:LFA RS03990
gene id: 1212491:LFA_RS03990
uniprot id: A0A098G1H8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

1212491:LFA RS06080
gene id: 1212491:LFA_RS06080
uniprot id: A0A098G470
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1212491:LFA RS05675
gene id: 1212491:LFA_RS05675
uniprot id: A0A098G2H9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1212491:LFA RS07865
gene id: 1212491:LFA_RS07865
uniprot id: A0A098G596
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1212491:LFA RS05995
gene id: 1212491:LFA_RS05995
uniprot id: A0A098G450
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS05605
gene id: 1212491:LFA_RS05605
uniprot id: A0A098G3X1
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1212491:LFA RS03835
gene id: 1212491:LFA_RS03835
uniprot id: A0A098G2U8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1212491:LFA RS10025
gene id: 1212491:LFA_RS10025
uniprot id: A0A098G6K6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1212491:LFA RS05895
gene id: 1212491:LFA_RS05895
uniprot id: A0A098G432
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

1212491:LFA RS00240
gene id: 1212491:LFA_RS00240
uniprot id: A0A098G219
names: Similarity
messages: Belongs to the ArsC family.

1212491:LFA RS12290
gene id: 1212491:LFA_RS12290
uniprot id: A0A098G6I8
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1212491:LFA RS06215
gene id: 1212491:LFA_RS06215
uniprot id: A0A098G4A0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1212491:LFA RS16035
gene id: 1212491:LFA_RS16035
uniprot id: A0A098GBG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1212491:LFA RS11475
gene id: 1212491:LFA_RS11475
uniprot id: A0A098G617
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1212491:LFA RS02660
gene id: 1212491:LFA_RS02660
uniprot id: A0A098G260
names: Similarity
messages: Belongs to the Dps family.

1212491:LFA RS07195
gene id: 1212491:LFA_RS07195
uniprot id: A0A098G4X4
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

1212491:LFA RS10555
gene id: 1212491:LFA_RS10555
uniprot id: A0A098G6T6
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1212491:LFA RS16680
gene id: 1212491:LFA_RS16680
uniprot id: A0A098G902
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1212491:LFA RS13930
gene id: 1212491:LFA_RS13930
uniprot id: A0A098G8U8
names: Similarity
messages: Belongs to the peptidase M56 family.

1212491:LFA RS06105
gene id: 1212491:LFA_RS06105
uniprot id: A0A098G5L5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1212491:LFA RS09590
gene id: 1212491:LFA_RS09590
uniprot id: A0A098G7L3
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS01355
gene id: 1212491:LFA_RS01355
uniprot id: A0A098FZX8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

1212491:LFA RS04975
gene id: 1212491:LFA_RS04975
uniprot id: A0A098G244
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1212491:LFA RS01350
gene id: 1212491:LFA_RS01350
uniprot id: A0A098FZX1
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

1212491:LFA RS09985
gene id: 1212491:LFA_RS09985
uniprot id: A0A098G6H9
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1212491:LFA RS07945
gene id: 1212491:LFA_RS07945
uniprot id: A0A098G3W8
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

1212491:LFA RS17805
gene id: 1212491:LFA_RS17805
uniprot id: A0A098G9N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1212491:LFA RS16755
gene id: 1212491:LFA_RS16755
uniprot id: A0A098G919
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS00765
gene id: 1212491:LFA_RS00765
uniprot id: A0A098FZJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1212491:LFA RS10095
gene id: 1212491:LFA_RS10095
uniprot id: A0A098G6L9
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1212491:LFA RS05865
gene id: 1212491:LFA_RS05865
uniprot id: A0A098G427
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

1212491:LFA RS12295
gene id: 1212491:LFA_RS12295
uniprot id: A0A098G6E4
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS07740
gene id: 1212491:LFA_RS07740
uniprot id: A0A098G3S5
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family. AstD subfamily.
messages: Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.

1212491:LFA RS17120
gene id: 1212491:LFA_RS17120
uniprot id: A0A098G964
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1212491:LFA RS01930
gene id: 1212491:LFA_RS01930
uniprot id: A0A098G326
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1212491:LFA RS16315
gene id: 1212491:LFA_RS16315
uniprot id: A0A098G8S5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS04445
gene id: 1212491:LFA_RS04445
uniprot id: A0A098G4N1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

1212491:LFA RS04480
gene id: 1212491:LFA_RS04480
uniprot id: A0A098G1U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. PilQ subfamily.
messages: Cell outer membrane
messages: Membrane

1212491:LFA RS07380
gene id: 1212491:LFA_RS07380
uniprot id: A0A098G3K6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1212491:LFA RS03155
gene id: 1212491:LFA_RS03155
uniprot id: A0A098G2F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1212491:LFA RS02530
gene id: 1212491:LFA_RS02530
uniprot id: A0A098G3G1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.

1212491:LFA RS09890
gene id: 1212491:LFA_RS09890
uniprot id: A0A098G524
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

1212491:LFA RS09415
gene id: 1212491:LFA_RS09415
uniprot id: A0A098G7I1
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS07320
gene id: 1212491:LFA_RS07320
uniprot id: A0A098G501
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

1212491:LFA RS13290
gene id: 1212491:LFA_RS13290
uniprot id: A0A098G8F1
names: Similarity
messages: Belongs to the peptidase S66 family.

1212491:LFA RS07630
gene id: 1212491:LFA_RS07630
uniprot id: A0A098G561
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1212491:LFA RS04015
gene id: 1212491:LFA_RS04015
uniprot id: A0A098G1I3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS17160
gene id: 1212491:LFA_RS17160
uniprot id: A0A098GAP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1212491:LFA RS16665
gene id: 1212491:LFA_RS16665
uniprot id: A0A098GAA5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1212491:LFA RS08675
gene id: 1212491:LFA_RS08675
uniprot id: A0A098G746
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1212491:LFA RS12650
gene id: 1212491:LFA_RS12650
uniprot id: A0A098G834
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1212491:LFA RS01525
gene id: 1212491:LFA_RS01525
uniprot id: A0A098G010
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1212491:LFA RS08000
gene id: 1212491:LFA_RS08000
uniprot id: A0A098G6R9
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS05460
gene id: 1212491:LFA_RS05460
uniprot id: A0A098G2G3
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS11160
gene id: 1212491:LFA_RS11160
uniprot id: A0A098G756
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1212491:LFA RS10685
gene id: 1212491:LFA_RS10685
uniprot id: A0A098G5G1
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS10430
gene id: 1212491:LFA_RS10430
uniprot id: A0A098G6R2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1212491:LFA RS05780
gene id: 1212491:LFA_RS05780
uniprot id: A0A098G2N1
names: Similarity
messages: Belongs to the glutamine synthetase family.

1212491:LFA RS16010
gene id: 1212491:LFA_RS16010
uniprot id: A0A098GBG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1212491:LFA RS05715
gene id: 1212491:LFA_RS05715
uniprot id: A0A098G5D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1212491:LFA RS17850
gene id: 1212491:LFA_RS17850
uniprot id: A0A098GB41
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1212491:LFA RS12950
gene id: 1212491:LFA_RS12950
uniprot id: A0A098G884
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Membrane

1212491:LFA RS05255
gene id: 1212491:LFA_RS05255
uniprot id: A0A098G3N1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of five rings (E,L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1212491:LFA RS06220
gene id: 1212491:LFA_RS06220
uniprot id: A0A098G5N8
names: Similarity
messages: Belongs to the PhoH family.

1212491:LFA RS12785
gene id: 1212491:LFA_RS12785
uniprot id: A0A098G858
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1212491:LFA RS12955
gene id: 1212491:LFA_RS12955
uniprot id: A0A098G9N0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

1212491:LFA RS08700
gene id: 1212491:LFA_RS08700
uniprot id: A0A098G752
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1212491:LFA RS07520
gene id: 1212491:LFA_RS07520
uniprot id: A0A098G6E3
names: Similarity
messages: Belongs to the DDAH family.

1212491:LFA RS14960
gene id: 1212491:LFA_RS14960
uniprot id: A0A098G815
names: Similarity
messages: Belongs to the thioesterase family.

1212491:LFA RS05900
gene id: 1212491:LFA_RS05900
uniprot id: A0A098G5H3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS11435
gene id: 1212491:LFA_RS11435
uniprot id: A0A098G7E2
names: Similarity
messages: Belongs to the peptidase S13 family.

1212491:LFA RS04385
gene id: 1212491:LFA_RS04385
uniprot id: A0A098G1S5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

1212491:LFA RS17465
gene id: 1212491:LFA_RS17465
uniprot id: A0A098G9G5
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

1212491:LFA RS03900
gene id: 1212491:LFA_RS03900
uniprot id: A0A098G2W1
names: Similarity
messages: Belongs to the catalase family.

1212491:LFA RS06010
gene id: 1212491:LFA_RS06010
uniprot id: A0A098G2Q1
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS10590
gene id: 1212491:LFA_RS10590
uniprot id: A0A098G5E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1212491:LFA RS09515
gene id: 1212491:LFA_RS09515
uniprot id: A0A098G7J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1212491:LFA RS11375
gene id: 1212491:LFA_RS11375
uniprot id: A0A098G799
names: Function
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1212491:LFA RS06850
gene id: 1212491:LFA_RS06850
uniprot id: A0A098G392
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Membrane

1212491:LFA RS13020
gene id: 1212491:LFA_RS13020
uniprot id: A0A098G899
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1212491:LFA RS05755
gene id: 1212491:LFA_RS05755
uniprot id: A0A098G2M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

1212491:LFA RS13960
gene id: 1212491:LFA_RS13960
uniprot id: A0A098G7G1
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1212491:LFA RS18555
gene id: 1212491:LFA_RS18555
uniprot id: A0A098GA87
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1212491:LFA RS11795
gene id: 1212491:LFA_RS11795
uniprot id: A0A098G685
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1212491:LFA RS07105
gene id: 1212491:LFA_RS07105
uniprot id: A0A098G3F3
names: Similarity
messages: Belongs to the PrpD family.

1212491:LFA RS09105
gene id: 1212491:LFA_RS09105
uniprot id: A0A098G4J3
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1212491:LFA RS12300
gene id: 1212491:LFA_RS12300
uniprot id: A0A098G7X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

1212491:LFA RS06350
gene id: 1212491:LFA_RS06350
uniprot id: A0A098G5R4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1212491:LFA RS06985
gene id: 1212491:LFA_RS06985
uniprot id: A0A098G4Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

1212491:LFA RS11405
gene id: 1212491:LFA_RS11405
uniprot id: A0A098G5V2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

1212491:LFA RS12840
gene id: 1212491:LFA_RS12840
uniprot id: A0A098G871
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1212491:LFA RS01910
gene id: 1212491:LFA_RS01910
uniprot id: A0A098G1M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

1212491:LFA RS10785
gene id: 1212491:LFA_RS10785
uniprot id: A0A098G5H8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1212491:LFA RS05300
gene id: 1212491:LFA_RS05300
uniprot id: A0A098G3P1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1212491:LFA RS11960
gene id: 1212491:LFA_RS11960
uniprot id: A0A098G954
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1212491:LFA RS16740
gene id: 1212491:LFA_RS16740
uniprot id: A0A098GAB9
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1212491:LFA RS08970
gene id: 1212491:LFA_RS08970
uniprot id: A0A098G5Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

1212491:LFA RS00170
gene id: 1212491:LFA_RS00170
uniprot id: A0A098G0N9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1212491:LFA RS15990
gene id: 1212491:LFA_RS15990
uniprot id: A0A098G8K8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1212491:LFA RS06840
gene id: 1212491:LFA_RS06840
uniprot id: A0A098G614
names: Similarity
messages: Belongs to the UPF0250 family.

1212491:LFA RS09420
gene id: 1212491:LFA_RS09420
uniprot id: A0A098G670
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1212491:LFA RS08040
gene id: 1212491:LFA_RS08040
uniprot id: A0A098G3Y8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1212491:LFA RS11490
gene id: 1212491:LFA_RS11490
uniprot id: A0A098G8V4
names: Similarity
messages: Belongs to the DprA/Smf family.

1212491:LFA RS11555
gene id: 1212491:LFA_RS11555
uniprot id: A0A098G7H0
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1212491:LFA RS10680
gene id: 1212491:LFA_RS10680
uniprot id: A0A098G5K0
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS01415
gene id: 1212491:LFA_RS01415
uniprot id: A0A098FZY1
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS09070
gene id: 1212491:LFA_RS09070
uniprot id: A0A098G4L2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1212491:LFA RS05650
gene id: 1212491:LFA_RS05650
uniprot id: A0A098G2H5
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS00760
gene id: 1212491:LFA_RS00760
uniprot id: A0A098FZJ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1212491:LFA RS13070
gene id: 1212491:LFA_RS13070
uniprot id: A0A098G8B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1212491:LFA RS11740
gene id: 1212491:LFA_RS11740
uniprot id: A0A098G7G9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

1212491:LFA RS18535
gene id: 1212491:LFA_RS18535
uniprot id: A0A098GA35
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TraA family.
messages: Cell inner membrane
messages: Membrane
messages: Monomer. Interacts with itself to form filaments; also interacts with TraQ.
messages: Secreted

1212491:LFA RS16945
gene id: 1212491:LFA_RS16945
uniprot id: A0A098G961
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1212491:LFA RS02730
gene id: 1212491:LFA_RS02730
uniprot id: A0A098G3K9
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

1212491:LFA RS17620
gene id: 1212491:LFA_RS17620
uniprot id: A0A098GCE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1212491:LFA RS15600
gene id: 1212491:LFA_RS15600
uniprot id: A0A098G8C5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1212491:LFA RS16570
gene id: 1212491:LFA_RS16570
uniprot id: A0A098GA86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1212491:LFA RS15460
gene id: 1212491:LFA_RS15460
uniprot id: A0A098G898
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1212491:LFA RS17115
gene id: 1212491:LFA_RS17115
uniprot id: A0A098G996
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1212491:LFA RS06835
gene id: 1212491:LFA_RS06835
uniprot id: A0A098G4M4
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1212491:LFA RS04520
gene id: 1212491:LFA_RS04520
uniprot id: A0A098G4P6
names: Subcellular Location Annotation
messages: Membrane

1212491:LFA RS13885
gene id: 1212491:LFA_RS13885
uniprot id: A0A098GA67
names: Similarity
messages: Belongs to the UPF0145 family.

1212491:LFA RS13140
gene id: 1212491:LFA_RS13140
uniprot id: A0A098G6X7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1212491:LFA RS00415
gene id: 1212491:LFA_RS00415
uniprot id: A0A098G258
names: Similarity
messages: Belongs to the glutamate synthase family.

1212491:LFA RS14105
gene id: 1212491:LFA_RS14105
uniprot id: A0A098G8V5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1212491:LFA RS10845
gene id: 1212491:LFA_RS10845
uniprot id: A0A098G8G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1212491:LFA RS13075
gene id: 1212491:LFA_RS13075
uniprot id: A0A098G9Q5
names: Similarity
messages: Belongs to the YkuD family.

1212491:LFA RS10450
gene id: 1212491:LFA_RS10450
uniprot id: A0A098G893
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

1212491:LFA RS03470
gene id: 1212491:LFA_RS03470
uniprot id: A0A098G2L9
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1212491:LFA RS11470
gene id: 1212491:LFA_RS11470
uniprot id: A0A098G7B7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1212491:LFA RS04505
gene id: 1212491:LFA_RS04505
uniprot id: A0A098G1U8
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

1212491:LFA RS01040
gene id: 1212491:LFA_RS01040
uniprot id: A0A098G2K1
names: Similarity
messages: Belongs to the ArsC family.

1212491:LFA RS01420
gene id: 1212491:LFA_RS01420
uniprot id: A0A098FZZ0
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

1212491:LFA RS04425
gene id: 1212491:LFA_RS04425
uniprot id: A0A098G4M7
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1212491:LFA RS13970
gene id: 1212491:LFA_RS13970
uniprot id: A0A098GA88
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.