1209989:TEPRE1 RS11745
gene id: 1209989:TEPRE1_RS11745
uniprot id: F4LT68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1209989:TEPRE1 RS04325
gene id: 1209989:TEPRE1_RS04325
uniprot id: F4LXD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1209989:TEPRE1 RS11180
gene id: 1209989:TEPRE1_RS11180
uniprot id: F4LS26
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

1209989:TEPRE1 RS11245
gene id: 1209989:TEPRE1_RS11245
uniprot id: F4LSI8
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1209989:TEPRE1 RS06050
gene id: 1209989:TEPRE1_RS06050
uniprot id: F4LTM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1209989:TEPRE1 RS01550
gene id: 1209989:TEPRE1_RS01550
uniprot id: F4LTI1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1209989:TEPRE1 RS03000
gene id: 1209989:TEPRE1_RS03000
uniprot id: F4LVU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0316 family.
messages: Cell membrane
messages: Membrane

1209989:TEPRE1 RS10160
gene id: 1209989:TEPRE1_RS10160
uniprot id: F4LR14
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1209989:TEPRE1 RS09530
gene id: 1209989:TEPRE1_RS09530
uniprot id: F4LQN8
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1209989:TEPRE1 RS13000
gene id: 1209989:TEPRE1_RS13000
uniprot id: F4LV57
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1209989:TEPRE1 RS06090
gene id: 1209989:TEPRE1_RS06090
uniprot id: F4LTN6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

1209989:TEPRE1 RS02320
gene id: 1209989:TEPRE1_RS02320
uniprot id: F4LUU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

1209989:TEPRE1 RS07860
gene id: 1209989:TEPRE1_RS07860
uniprot id: F4LWB5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1209989:TEPRE1 RS03350
gene id: 1209989:TEPRE1_RS03350
uniprot id: F4LW72
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1209989:TEPRE1 RS05950
gene id: 1209989:TEPRE1_RS05950
uniprot id: F4LTK8
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1209989:TEPRE1 RS01165
gene id: 1209989:TEPRE1_RS01165
uniprot id: F4LSY0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1209989:TEPRE1 RS00460
gene id: 1209989:TEPRE1_RS00460
uniprot id: F4LS41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1209989:TEPRE1 RS01990
gene id: 1209989:TEPRE1_RS01990
uniprot id: F4LUM9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS01710
gene id: 1209989:TEPRE1_RS01710
uniprot id: F4LU18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1209989:TEPRE1 RS06185
gene id: 1209989:TEPRE1_RS06185
uniprot id: F4LTQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1209989:TEPRE1 RS02450
gene id: 1209989:TEPRE1_RS02450
uniprot id: F4LVB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1209989:TEPRE1 RS00960
gene id: 1209989:TEPRE1_RS00960
uniprot id: F4LST9
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1209989:TEPRE1 RS10030
gene id: 1209989:TEPRE1_RS10030
uniprot id: F4LQY8
names: Similarity
messages: Belongs to the UPF0309 family.

1209989:TEPRE1 RS00950
gene id: 1209989:TEPRE1_RS00950
uniprot id: F4LST7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1209989:TEPRE1 RS01030
gene id: 1209989:TEPRE1_RS01030
uniprot id: F4LSV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1209989:TEPRE1 RS10335
gene id: 1209989:TEPRE1_RS10335
uniprot id: F4LR48
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1209989:TEPRE1 RS12790
gene id: 1209989:TEPRE1_RS12790
uniprot id: F4LUL5
names: Similarity
messages: Belongs to the UPF0178 family.

1209989:TEPRE1 RS01025
gene id: 1209989:TEPRE1_RS01025
uniprot id: F4LSV2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1209989:TEPRE1 RS08250
gene id: 1209989:TEPRE1_RS08250
uniprot id: F4LWR4
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

1209989:TEPRE1 RS08000
gene id: 1209989:TEPRE1_RS08000
uniprot id: F4LWE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

1209989:TEPRE1 RS01750
gene id: 1209989:TEPRE1_RS01750
uniprot id: F4LU25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1209989:TEPRE1 RS07840
gene id: 1209989:TEPRE1_RS07840
uniprot id: F4LWB1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1209989:TEPRE1 RS09705
gene id: 1209989:TEPRE1_RS09705
uniprot id: F4LQS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1209989:TEPRE1 RS06985
gene id: 1209989:TEPRE1_RS06985
uniprot id: F4LV15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1209989:TEPRE1 RS06010
gene id: 1209989:TEPRE1_RS06010
uniprot id: F4LTM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

1209989:TEPRE1 RS08740
gene id: 1209989:TEPRE1_RS08740
uniprot id: F4LX86
names: Similarity
messages: Belongs to the FGGY kinase family.

1209989:TEPRE1 RS06100
gene id: 1209989:TEPRE1_RS06100
uniprot id: F4LTN8
names: Subcellular Location Annotation
messages: Cytoplasm

1209989:TEPRE1 RS08355
gene id: 1209989:TEPRE1_RS08355
uniprot id: F4LWT5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1209989:TEPRE1 RS06345
gene id: 1209989:TEPRE1_RS06345
uniprot id: F4LU87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1209989:TEPRE1 RS10880
gene id: 1209989:TEPRE1_RS10880
uniprot id: F4LRW4
names: Activity Regulation
names: Function
names: Similarity
messages: Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.

1209989:TEPRE1 RS07795
gene id: 1209989:TEPRE1_RS07795
uniprot id: F4LWA2
names: Similarity
messages: Belongs to the threonine aldolase family.

1209989:TEPRE1 RS13080
gene id: 1209989:TEPRE1_RS13080
uniprot id: F4LV70
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1209989:TEPRE1 RS13060
gene id: 1209989:TEPRE1_RS13060
uniprot id: F4LV66
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

1209989:TEPRE1 RS05965
gene id: 1209989:TEPRE1_RS05965
uniprot id: F4LTL1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1209989:TEPRE1 RS07585
gene id: 1209989:TEPRE1_RS07585
uniprot id: F4LVZ3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1209989:TEPRE1 RS00660
gene id: 1209989:TEPRE1_RS00660
uniprot id: F4LS78
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1209989:TEPRE1 RS07145
gene id: 1209989:TEPRE1_RS07145
uniprot id: F4LVI7
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1209989:TEPRE1 RS02530
gene id: 1209989:TEPRE1_RS02530
uniprot id: F4LVC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1209989:TEPRE1 RS10840
gene id: 1209989:TEPRE1_RS10840
uniprot id: F4LRF9
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1209989:TEPRE1 RS12365
gene id: 1209989:TEPRE1_RS12365
uniprot id: F4LTX9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS10500
gene id: 1209989:TEPRE1_RS10500
uniprot id: F4LR98
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS09855
gene id: 1209989:TEPRE1_RS09855
uniprot id: F4LQV2
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1209989:TEPRE1 RS01740
gene id: 1209989:TEPRE1_RS01740
uniprot id: F4LU23
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1209989:TEPRE1 RS13150
gene id: 1209989:TEPRE1_RS13150
uniprot id: F4LV84
names: Similarity
messages: Belongs to the ParB family.

1209989:TEPRE1 RS12390
gene id: 1209989:TEPRE1_RS12390
uniprot id: F4LTY4
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

1209989:TEPRE1 RS09755
gene id: 1209989:TEPRE1_RS09755
uniprot id: F4LQT2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1209989:TEPRE1 RS04880
gene id: 1209989:TEPRE1_RS04880
uniprot id: F4LRR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1209989:TEPRE1 RS07150
gene id: 1209989:TEPRE1_RS07150
uniprot id: F4LVI8
names: Similarity
messages: Belongs to the UPF0473 family.

1209989:TEPRE1 RS11225
gene id: 1209989:TEPRE1_RS11225
uniprot id: F4LS35
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1209989:TEPRE1 RS01630
gene id: 1209989:TEPRE1_RS01630
uniprot id: F4LU02
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1209989:TEPRE1 RS02515
gene id: 1209989:TEPRE1_RS02515
uniprot id: F4LVC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1209989:TEPRE1 RS07190
gene id: 1209989:TEPRE1_RS07190
uniprot id: F4LVJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Membrane

1209989:TEPRE1 RS09485
gene id: 1209989:TEPRE1_RS09485
uniprot id: F4LQM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1209989:TEPRE1 RS05330
gene id: 1209989:TEPRE1_RS05330
uniprot id: F4LSF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1209989:TEPRE1 RS06965
gene id: 1209989:TEPRE1_RS06965
uniprot id: F4LV11
names: Similarity
messages: Belongs to the TlyA family.

1209989:TEPRE1 RS02905
gene id: 1209989:TEPRE1_RS02905
uniprot id: F4LVS4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1209989:TEPRE1 RS07595
gene id: 1209989:TEPRE1_RS07595
uniprot id: F4LVZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1209989:TEPRE1 RS02170
gene id: 1209989:TEPRE1_RS02170
uniprot id: F4LUR4
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1209989:TEPRE1 RS06040
gene id: 1209989:TEPRE1_RS06040
uniprot id: F4LTM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1209989:TEPRE1 RS06540
gene id: 1209989:TEPRE1_RS06540
uniprot id: F4LUC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane

1209989:TEPRE1 RS06260
gene id: 1209989:TEPRE1_RS06260
uniprot id: F4LU70
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1209989:TEPRE1 RS10025
gene id: 1209989:TEPRE1_RS10025
uniprot id: F4LQY7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

1209989:TEPRE1 RS01575
gene id: 1209989:TEPRE1_RS01575
uniprot id: F4LTI6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1209989:TEPRE1 RS11120
gene id: 1209989:TEPRE1_RS11120
uniprot id: F4LS13
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

1209989:TEPRE1 RS06680
gene id: 1209989:TEPRE1_RS06680
uniprot id: F4LUV7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1209989:TEPRE1 RS04055
gene id: 1209989:TEPRE1_RS04055
uniprot id: F4LX06
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1209989:TEPRE1 RS02825
gene id: 1209989:TEPRE1_RS02825
uniprot id: F4LVQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1209989:TEPRE1 RS10905
gene id: 1209989:TEPRE1_RS10905
uniprot id: F4LRW9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1209989:TEPRE1 RS06265
gene id: 1209989:TEPRE1_RS06265
uniprot id: F4LU71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1209989:TEPRE1 RS01045
gene id: 1209989:TEPRE1_RS01045
uniprot id: F4LSV6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1209989:TEPRE1 RS11110
gene id: 1209989:TEPRE1_RS11110
uniprot id: F4LS11
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1209989:TEPRE1 RS01090
gene id: 1209989:TEPRE1_RS01090
uniprot id: F4LSW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1209989:TEPRE1 RS07800
gene id: 1209989:TEPRE1_RS07800
uniprot id: F4LWA3
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS01765
gene id: 1209989:TEPRE1_RS01765
uniprot id: F4LU28
names: Similarity
messages: Belongs to the SfsA family.

1209989:TEPRE1 RS04830
gene id: 1209989:TEPRE1_RS04830
uniprot id: F4LRQ0
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1209989:TEPRE1 RS10760
gene id: 1209989:TEPRE1_RS10760
uniprot id: F4LRE7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1209989:TEPRE1 RS06600
gene id: 1209989:TEPRE1_RS06600
uniprot id: F4LUD8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1209989:TEPRE1 RS02140
gene id: 1209989:TEPRE1_RS02140
uniprot id: F4LUQ9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

1209989:TEPRE1 RS01745
gene id: 1209989:TEPRE1_RS01745
uniprot id: F4LU24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1209989:TEPRE1 RS09350
gene id: 1209989:TEPRE1_RS09350
uniprot id: F4LQK1
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS00650
gene id: 1209989:TEPRE1_RS00650
uniprot id: F4LS76
names: Similarity
messages: Belongs to the UPF0597 family.

1209989:TEPRE1 RS06340
gene id: 1209989:TEPRE1_RS06340
uniprot id: F4LU86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1209989:TEPRE1 RS04165
gene id: 1209989:TEPRE1_RS04165
uniprot id: F4LX26
names: Similarity
messages: Belongs to the FlgM family.

1209989:TEPRE1 RS00455
gene id: 1209989:TEPRE1_RS00455
uniprot id: F4LS40
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1209989:TEPRE1 RS09120
gene id: 1209989:TEPRE1_RS09120
uniprot id: F4LXN1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1209989:TEPRE1 RS08980
gene id: 1209989:TEPRE1_RS08980
uniprot id: F4LXK3
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1209989:TEPRE1 RS02240
gene id: 1209989:TEPRE1_RS02240
uniprot id: F4LUS8
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS10145
gene id: 1209989:TEPRE1_RS10145
uniprot id: L0S592
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1209989:TEPRE1 RS06155
gene id: 1209989:TEPRE1_RS06155
uniprot id: F4LTP9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

1209989:TEPRE1 RS04470
gene id: 1209989:TEPRE1_RS04470
uniprot id: F4LXG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1209989:TEPRE1 RS05670
gene id: 1209989:TEPRE1_RS05670
uniprot id: F4LT18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1209989:TEPRE1 RS03520
gene id: 1209989:TEPRE1_RS03520
uniprot id: F4LWH5
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

1209989:TEPRE1 RS00830
gene id: 1209989:TEPRE1_RS00830
uniprot id: F4LSR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1209989:TEPRE1 RS01470
gene id: 1209989:TEPRE1_RS01470
uniprot id: F4LTG5
names: Subcellular Location Annotation
messages: Cell membrane

1209989:TEPRE1 RS06045
gene id: 1209989:TEPRE1_RS06045
uniprot id: F4LTM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

1209989:TEPRE1 RS07870
gene id: 1209989:TEPRE1_RS07870
uniprot id: F4LWB7
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS04950
gene id: 1209989:TEPRE1_RS04950
uniprot id: F4LRS4
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS07315
gene id: 1209989:TEPRE1_RS07315
uniprot id: F4LVM1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1209989:TEPRE1 RS06510
gene id: 1209989:TEPRE1_RS06510
uniprot id: F4LUC0
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1209989:TEPRE1 RS10535
gene id: 1209989:TEPRE1_RS10535
uniprot id: F4LRA5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1209989:TEPRE1 RS11205
gene id: 1209989:TEPRE1_RS11205
uniprot id: F4LS31
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1209989:TEPRE1 RS00680
gene id: 1209989:TEPRE1_RS00680
uniprot id: F4LS82
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1209989:TEPRE1 RS09135
gene id: 1209989:TEPRE1_RS09135
uniprot id: F4LXN4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS01055
gene id: 1209989:TEPRE1_RS01055
uniprot id: F4LSV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1209989:TEPRE1 RS01005
gene id: 1209989:TEPRE1_RS01005
uniprot id: F4LSU8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1209989:TEPRE1 RS02060
gene id: 1209989:TEPRE1_RS02060
uniprot id: F4LUP3
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS12950
gene id: 1209989:TEPRE1_RS12950
uniprot id: F4LV47
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

1209989:TEPRE1 RS11370
gene id: 1209989:TEPRE1_RS11370
uniprot id: F4LSL1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1209989:TEPRE1 RS02380
gene id: 1209989:TEPRE1_RS02380
uniprot id: F4LV99
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS05480
gene id: 1209989:TEPRE1_RS05480
uniprot id: F4LSI3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1209989:TEPRE1 RS00465
gene id: 1209989:TEPRE1_RS00465
uniprot id: F4LS42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1209989:TEPRE1 RS03020
gene id: 1209989:TEPRE1_RS03020
uniprot id: F4LVU4
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1209989:TEPRE1 RS05595
gene id: 1209989:TEPRE1_RS05595
uniprot id: F4LT03
names: Similarity
messages: Belongs to the hemerythrin family.

1209989:TEPRE1 RS00930
gene id: 1209989:TEPRE1_RS00930
uniprot id: F4LRF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1209989:TEPRE1 RS03860
gene id: 1209989:TEPRE1_RS03860
uniprot id: F4LWP2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1209989:TEPRE1 RS03955
gene id: 1209989:TEPRE1_RS03955
uniprot id: F4LWY6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1209989:TEPRE1 RS01975
gene id: 1209989:TEPRE1_RS01975
uniprot id: F4LUM6
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1209989:TEPRE1 RS05005
gene id: 1209989:TEPRE1_RS05005
uniprot id: F4LRT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1209989:TEPRE1 RS01135
gene id: 1209989:TEPRE1_RS01135
uniprot id: F4LSX4
names: Similarity
messages: Belongs to the EamA transporter family.

1209989:TEPRE1 RS04890
gene id: 1209989:TEPRE1_RS04890
uniprot id: F4LRR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

1209989:TEPRE1 RS01105
gene id: 1209989:TEPRE1_RS01105
uniprot id: F4LSW8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS10770
gene id: 1209989:TEPRE1_RS10770
uniprot id: F4LRE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1209989:TEPRE1 RS01325
gene id: 1209989:TEPRE1_RS01325
uniprot id: F4LTD9
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

1209989:TEPRE1 RS03460
gene id: 1209989:TEPRE1_RS03460
uniprot id: F4LW88
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1209989:TEPRE1 RS01370
gene id: 1209989:TEPRE1_RS01370
uniprot id: F4LTE6
names: Subcellular Location Annotation
messages: Cytoplasm

1209989:TEPRE1 RS00425
gene id: 1209989:TEPRE1_RS00425
uniprot id: F4LRN4
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1209989:TEPRE1 RS07355
gene id: 1209989:TEPRE1_RS07355
uniprot id: F4LVM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1209989:TEPRE1 RS00920
gene id: 1209989:TEPRE1_RS00920
uniprot id: F4LST1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1209989:TEPRE1 RS00990
gene id: 1209989:TEPRE1_RS00990
uniprot id: F4LSU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1209989:TEPRE1 RS01080
gene id: 1209989:TEPRE1_RS01080
uniprot id: F4LSW3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1209989:TEPRE1 RS04815
gene id: 1209989:TEPRE1_RS04815
uniprot id: F4LRP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily.
messages: Catalyzes the interconversion of ornithine to glutamate semialdehyde.
messages: Cytoplasm

1209989:TEPRE1 RS11705
gene id: 1209989:TEPRE1_RS11705
uniprot id: F4LT60
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS03685
gene id: 1209989:TEPRE1_RS03685
uniprot id: F4LWK8
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS07525
gene id: 1209989:TEPRE1_RS07525
uniprot id: F4LVY0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1209989:TEPRE1 RS06585
gene id: 1209989:TEPRE1_RS06585
uniprot id: F4LUD5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1209989:TEPRE1 RS01110
gene id: 1209989:TEPRE1_RS01110
uniprot id: F4LSW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1209989:TEPRE1 RS05570
gene id: 1209989:TEPRE1_RS05570
uniprot id: F4LSZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1209989:TEPRE1 RS08255
gene id: 1209989:TEPRE1_RS08255
uniprot id: F4LWR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1209989:TEPRE1 RS03305
gene id: 1209989:TEPRE1_RS03305
uniprot id: F4LW64
names: Similarity
messages: Belongs to the creatininase superfamily.

1209989:TEPRE1 RS09100
gene id: 1209989:TEPRE1_RS09100
uniprot id: F4LXM7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1209989:TEPRE1 RS00500
gene id: 1209989:TEPRE1_RS00500
uniprot id: F4LS49
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1209989:TEPRE1 RS03900
gene id: 1209989:TEPRE1_RS03900
uniprot id: F4LWX5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1209989:TEPRE1 RS12780
gene id: 1209989:TEPRE1_RS12780
uniprot id: F4LUL3
names: Similarity
messages: Belongs to the MEMO1 family.

1209989:TEPRE1 RS14070
gene id: 1209989:TEPRE1_RS14070
uniprot id: F4LQV0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1209989:TEPRE1 RS08105
gene id: 1209989:TEPRE1_RS08105
uniprot id: F4LWG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1209989:TEPRE1 RS03960
gene id: 1209989:TEPRE1_RS03960
uniprot id: F4LWY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1209989:TEPRE1 RS07165
gene id: 1209989:TEPRE1_RS07165
uniprot id: F4LVJ1
names: Similarity
messages: Belongs to the UPF0297 family.

1209989:TEPRE1 RS00270
gene id: 1209989:TEPRE1_RS00270
uniprot id: F4LRK4
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

1209989:TEPRE1 RS12595
gene id: 1209989:TEPRE1_RS12595
uniprot id: F4LUH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1209989:TEPRE1 RS01215
gene id: 1209989:TEPRE1_RS01215
uniprot id: F4LTB8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS08280
gene id: 1209989:TEPRE1_RS08280
uniprot id: F4LWS0
names: Similarity
messages: Belongs to the peptidase S41A family.

1209989:TEPRE1 RS00800
gene id: 1209989:TEPRE1_RS00800
uniprot id: F4LSA7
names: Similarity
messages: Belongs to the RutC family.

1209989:TEPRE1 RS12760
gene id: 1209989:TEPRE1_RS12760
uniprot id: F4LUK9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS06445
gene id: 1209989:TEPRE1_RS06445
uniprot id: F4LUA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1209989:TEPRE1 RS12725
gene id: 1209989:TEPRE1_RS12725
uniprot id: F4LUK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1209989:TEPRE1 RS00010
gene id: 1209989:TEPRE1_RS00010
uniprot id: F4LR74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1209989:TEPRE1 RS08745
gene id: 1209989:TEPRE1_RS08745
uniprot id: F4LX87
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1209989:TEPRE1 RS11675
gene id: 1209989:TEPRE1_RS11675
uniprot id: F4LT54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1209989:TEPRE1 RS12720
gene id: 1209989:TEPRE1_RS12720
uniprot id: F4LUK0
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS09885
gene id: 1209989:TEPRE1_RS09885
uniprot id: F4LQV8
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

1209989:TEPRE1 RS03705
gene id: 1209989:TEPRE1_RS03705
uniprot id: F4LWL2
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

1209989:TEPRE1 RS00045
gene id: 1209989:TEPRE1_RS00045
uniprot id: F4LRG1
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1209989:TEPRE1 RS10175
gene id: 1209989:TEPRE1_RS10175
uniprot id: F4LR17
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1209989:TEPRE1 RS01100
gene id: 1209989:TEPRE1_RS01100
uniprot id: F4LSW7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

1209989:TEPRE1 RS02415
gene id: 1209989:TEPRE1_RS02415
uniprot id: F4LVA6
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1209989:TEPRE1 RS10355
gene id: 1209989:TEPRE1_RS10355
uniprot id: F4LR52
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.

1209989:TEPRE1 RS07780
gene id: 1209989:TEPRE1_RS07780
uniprot id: F4LW29
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

1209989:TEPRE1 RS07415
gene id: 1209989:TEPRE1_RS07415
uniprot id: F4LVV9
names: Subcellular Location Annotation
messages: Cytoplasm

1209989:TEPRE1 RS02210
gene id: 1209989:TEPRE1_RS02210
uniprot id: F4LUS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1209989:TEPRE1 RS08175
gene id: 1209989:TEPRE1_RS08175
uniprot id: F4LWQ3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1209989:TEPRE1 RS08615
gene id: 1209989:TEPRE1_RS08615
uniprot id: F4LX61
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS10835
gene id: 1209989:TEPRE1_RS10835
uniprot id: F4LRF8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1209989:TEPRE1 RS09380
gene id: 1209989:TEPRE1_RS09380
uniprot id: F4LQK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1209989:TEPRE1 RS09850
gene id: 1209989:TEPRE1_RS09850
uniprot id: F4LQV1
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1209989:TEPRE1 RS07390
gene id: 1209989:TEPRE1_RS07390
uniprot id: F4LVN6
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

1209989:TEPRE1 RS05775
gene id: 1209989:TEPRE1_RS05775
uniprot id: F4LT39
names: Similarity
messages: Belongs to the acylphosphatase family.

1209989:TEPRE1 RS07705
gene id: 1209989:TEPRE1_RS07705
uniprot id: F4LW18
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1209989:TEPRE1 RS07330
gene id: 1209989:TEPRE1_RS07330
uniprot id: F4LVM4
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1209989:TEPRE1 RS09230
gene id: 1209989:TEPRE1_RS09230
uniprot id: F4LXQ2
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1209989:TEPRE1 RS00230
gene id: 1209989:TEPRE1_RS00230
uniprot id: F4LRJ7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1209989:TEPRE1 RS03135
gene id: 1209989:TEPRE1_RS03135
uniprot id: F4LW31
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1209989:TEPRE1 RS05580
gene id: 1209989:TEPRE1_RS05580
uniprot id: F4LT00
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1209989:TEPRE1 RS03065
gene id: 1209989:TEPRE1_RS03065
uniprot id: F4LVU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1209989:TEPRE1 RS10955
gene id: 1209989:TEPRE1_RS10955
uniprot id: F4LRX9
names: Similarity
messages: Belongs to the Fur family.

1209989:TEPRE1 RS06755
gene id: 1209989:TEPRE1_RS06755
uniprot id: F4LUW8
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1209989:TEPRE1 RS06430
gene id: 1209989:TEPRE1_RS06430
uniprot id: F4LUA4
names: Similarity
messages: Belongs to the AAA ATPase family.
messages: In the C-terminal section; belongs to the peptidase M41 family.

1209989:TEPRE1 RS04395
gene id: 1209989:TEPRE1_RS04395
uniprot id: F4LXE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1209989:TEPRE1 RS03295
gene id: 1209989:TEPRE1_RS03295
uniprot id: F4LW63
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS06550
gene id: 1209989:TEPRE1_RS06550
uniprot id: F4LUC8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1209989:TEPRE1 RS01895
gene id: 1209989:TEPRE1_RS01895
uniprot id: F4LU52
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1209989:TEPRE1 RS06385
gene id: 1209989:TEPRE1_RS06385
uniprot id: F4LU95
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1209989:TEPRE1 RS07005
gene id: 1209989:TEPRE1_RS07005
uniprot id: F4LV19
names: Similarity
messages: Belongs to the asp23 family.

1209989:TEPRE1 RS11105
gene id: 1209989:TEPRE1_RS11105
uniprot id: F4LS10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

1209989:TEPRE1 RS07900
gene id: 1209989:TEPRE1_RS07900
uniprot id: F4LWC3
names: Function
names: Similarity
messages: Belongs to the UxaE family.
messages: Catalyzes the epimerization of D-tagaturonate (D-TagA) to D-fructuronate (D-FruA).

1209989:TEPRE1 RS08425
gene id: 1209989:TEPRE1_RS08425
uniprot id: F4LWU9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1209989:TEPRE1 RS02765
gene id: 1209989:TEPRE1_RS02765
uniprot id: F4LVP6
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1209989:TEPRE1 RS00900
gene id: 1209989:TEPRE1_RS00900
uniprot id: F4LSS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1209989:TEPRE1 RS12270
gene id: 1209989:TEPRE1_RS12270
uniprot id: F4LTW1
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS05855
gene id: 1209989:TEPRE1_RS05855
uniprot id: F4LT49
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1209989:TEPRE1 RS13915
gene id: 1209989:TEPRE1_RS13915
uniprot id: L0S205
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

1209989:TEPRE1 RS00525
gene id: 1209989:TEPRE1_RS00525
uniprot id: F4LS54
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

1209989:TEPRE1 RS07185
gene id: 1209989:TEPRE1_RS07185
uniprot id: F4LVJ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS01935
gene id: 1209989:TEPRE1_RS01935
uniprot id: F4LU60
names: Similarity
messages: Belongs to the EamA transporter family.

1209989:TEPRE1 RS02595
gene id: 1209989:TEPRE1_RS02595
uniprot id: F4LVE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1209989:TEPRE1 RS05730
gene id: 1209989:TEPRE1_RS05730
uniprot id: F4LT30
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1209989:TEPRE1 RS08235
gene id: 1209989:TEPRE1_RS08235
uniprot id: F4LWR3
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS07155
gene id: 1209989:TEPRE1_RS07155
uniprot id: F4LVI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1209989:TEPRE1 RS12840
gene id: 1209989:TEPRE1_RS12840
uniprot id: F4LV23
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1209989:TEPRE1 RS00765
gene id: 1209989:TEPRE1_RS00765
uniprot id: F4LSA0
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: This protein is a Fe-Mo-cofactor biosynthetic component.

1209989:TEPRE1 RS05425
gene id: 1209989:TEPRE1_RS05425
uniprot id: F4LSH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1209989:TEPRE1 RS09455
gene id: 1209989:TEPRE1_RS09455
uniprot id: F4LQM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1209989:TEPRE1 RS03765
gene id: 1209989:TEPRE1_RS03765
uniprot id: F4LWM4
names: Similarity
messages: Belongs to the DtxR/MntR family.

1209989:TEPRE1 RS04175
gene id: 1209989:TEPRE1_RS04175
uniprot id: F4LX28
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1209989:TEPRE1 RS10765
gene id: 1209989:TEPRE1_RS10765
uniprot id: F4LRE8
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1209989:TEPRE1 RS05435
gene id: 1209989:TEPRE1_RS05435
uniprot id: F4LSH4
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1209989:TEPRE1 RS10875
gene id: 1209989:TEPRE1_RS10875
uniprot id: F4LRW3
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1209989:TEPRE1 RS01640
gene id: 1209989:TEPRE1_RS01640
uniprot id: F4LU04
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS06685
gene id: 1209989:TEPRE1_RS06685
uniprot id: F4LUV8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1209989:TEPRE1 RS08150
gene id: 1209989:TEPRE1_RS08150
uniprot id: F4LWH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1209989:TEPRE1 RS04190
gene id: 1209989:TEPRE1_RS04190
uniprot id: F4LX31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

1209989:TEPRE1 RS09600
gene id: 1209989:TEPRE1_RS09600
uniprot id: F4LQQ2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS03575
gene id: 1209989:TEPRE1_RS03575
uniprot id: F4LWI6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1209989:TEPRE1 RS11055
gene id: 1209989:TEPRE1_RS11055
uniprot id: F4LS00
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.

1209989:TEPRE1 RS04525
gene id: 1209989:TEPRE1_RS04525
uniprot id: F4LXG9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1209989:TEPRE1 RS06945
gene id: 1209989:TEPRE1_RS06945
uniprot id: F4LV07
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1209989:TEPRE1 RS12825
gene id: 1209989:TEPRE1_RS12825
uniprot id: F4LUM2
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1209989:TEPRE1 RS08220
gene id: 1209989:TEPRE1_RS08220
uniprot id: F4LWR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1209989:TEPRE1 RS06270
gene id: 1209989:TEPRE1_RS06270
uniprot id: F4LU72
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS03130
gene id: 1209989:TEPRE1_RS03130
uniprot id: F4LW30
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS10210
gene id: 1209989:TEPRE1_RS10210
uniprot id: F4LR24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1209989:TEPRE1 RS01455
gene id: 1209989:TEPRE1_RS01455
uniprot id: F4LTG2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1209989:TEPRE1 RS10005
gene id: 1209989:TEPRE1_RS10005
uniprot id: F4LQY3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1209989:TEPRE1 RS12305
gene id: 1209989:TEPRE1_RS12305
uniprot id: F4LTW8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

1209989:TEPRE1 RS09965
gene id: 1209989:TEPRE1_RS09965
uniprot id: F4LQX4
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1209989:TEPRE1 RS06580
gene id: 1209989:TEPRE1_RS06580
uniprot id: F4LUD4
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

1209989:TEPRE1 RS06080
gene id: 1209989:TEPRE1_RS06080
uniprot id: F4LTN4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1209989:TEPRE1 RS08715
gene id: 1209989:TEPRE1_RS08715
uniprot id: F4LX82
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS00965
gene id: 1209989:TEPRE1_RS00965
uniprot id: F4LSU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1209989:TEPRE1 RS00755
gene id: 1209989:TEPRE1_RS00755
uniprot id: F4LS98
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS07555
gene id: 1209989:TEPRE1_RS07555
uniprot id: F4LVY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1209989:TEPRE1 RS03345
gene id: 1209989:TEPRE1_RS03345
uniprot id: F4LW71
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1209989:TEPRE1 RS09395
gene id: 1209989:TEPRE1_RS09395
uniprot id: F4LQL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1209989:TEPRE1 RS07170
gene id: 1209989:TEPRE1_RS07170
uniprot id: F4LVJ2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1209989:TEPRE1 RS10870
gene id: 1209989:TEPRE1_RS10870
uniprot id: F4LRW2
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1209989:TEPRE1 RS07400
gene id: 1209989:TEPRE1_RS07400
uniprot id: F4LVN8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1209989:TEPRE1 RS10640
gene id: 1209989:TEPRE1_RS10640
uniprot id: F4LRC6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1209989:TEPRE1 RS02345
gene id: 1209989:TEPRE1_RS02345
uniprot id: F4LUU9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

1209989:TEPRE1 RS10520
gene id: 1209989:TEPRE1_RS10520
uniprot id: F4LRA2
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1209989:TEPRE1 RS09490
gene id: 1209989:TEPRE1_RS09490
uniprot id: F4LQN0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

1209989:TEPRE1 RS10900
gene id: 1209989:TEPRE1_RS10900
uniprot id: F4LRW8
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

1209989:TEPRE1 RS06255
gene id: 1209989:TEPRE1_RS06255
uniprot id: F4LU69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1209989:TEPRE1 RS09660
gene id: 1209989:TEPRE1_RS09660
uniprot id: F4LQR4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1209989:TEPRE1 RS11255
gene id: 1209989:TEPRE1_RS11255
uniprot id: F4LSJ0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1209989:TEPRE1 RS00205
gene id: 1209989:TEPRE1_RS00205
uniprot id: F4LRJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1209989:TEPRE1 RS01965
gene id: 1209989:TEPRE1_RS01965
uniprot id: F4LU66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1209989:TEPRE1 RS07450
gene id: 1209989:TEPRE1_RS07450
uniprot id: F4LVW5
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1209989:TEPRE1 RS06005
gene id: 1209989:TEPRE1_RS06005
uniprot id: F4LTL9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1209989:TEPRE1 RS01725
gene id: 1209989:TEPRE1_RS01725
uniprot id: F4LU20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diaminopimelate dehydrogenase family.
messages: Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.
messages: Homodimer.

1209989:TEPRE1 RS02550
gene id: 1209989:TEPRE1_RS02550
uniprot id: F4LVD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane

1209989:TEPRE1 RS00735
gene id: 1209989:TEPRE1_RS00735
uniprot id: F4LS94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1209989:TEPRE1 RS11415
gene id: 1209989:TEPRE1_RS11415
uniprot id: F4LSM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1209989:TEPRE1 RS03590
gene id: 1209989:TEPRE1_RS03590
uniprot id: F4LWI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1209989:TEPRE1 RS11805
gene id: 1209989:TEPRE1_RS11805
uniprot id: F4LT80
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS07695
gene id: 1209989:TEPRE1_RS07695
uniprot id: F4LW16
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS03475
gene id: 1209989:TEPRE1_RS03475
uniprot id: F4LW91
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.

1209989:TEPRE1 RS07570
gene id: 1209989:TEPRE1_RS07570
uniprot id: F4LVZ0
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1209989:TEPRE1 RS10135
gene id: 1209989:TEPRE1_RS10135
uniprot id: F4LR09
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS12515
gene id: 1209989:TEPRE1_RS12515
uniprot id: F4LUG0
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1209989:TEPRE1 RS10245
gene id: 1209989:TEPRE1_RS10245
uniprot id: F4LR31
names: Similarity
messages: Belongs to the UPF0111 family.

1209989:TEPRE1 RS08375
gene id: 1209989:TEPRE1_RS08375
uniprot id: F4LWT9
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS09760
gene id: 1209989:TEPRE1_RS09760
uniprot id: F4LQT3
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS02195
gene id: 1209989:TEPRE1_RS02195
uniprot id: F4LUR9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1209989:TEPRE1 RS10570
gene id: 1209989:TEPRE1_RS10570
uniprot id: F4LRB2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1209989:TEPRE1 RS03375
gene id: 1209989:TEPRE1_RS03375
uniprot id: F4LW77
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1209989:TEPRE1 RS05180
gene id: 1209989:TEPRE1_RS05180
uniprot id: F4LSC5
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

1209989:TEPRE1 RS11985
gene id: 1209989:TEPRE1_RS11985
uniprot id: F4LTA2
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

1209989:TEPRE1 RS05985
gene id: 1209989:TEPRE1_RS05985
uniprot id: F4LTL5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1209989:TEPRE1 RS08625
gene id: 1209989:TEPRE1_RS08625
uniprot id: F4LX63
names: Subcellular Location Annotation
messages: Cytoplasm

1209989:TEPRE1 RS11020
gene id: 1209989:TEPRE1_RS11020
uniprot id: F4LRZ3
names: Similarity
messages: Belongs to the RuBisCO large chain family.

1209989:TEPRE1 RS12600
gene id: 1209989:TEPRE1_RS12600
uniprot id: F4LUH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

1209989:TEPRE1 RS02970
gene id: 1209989:TEPRE1_RS02970
uniprot id: F4LVT4
names: Caution
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS09300
gene id: 1209989:TEPRE1_RS09300
uniprot id: F4LXR5
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

1209989:TEPRE1 RS05390
gene id: 1209989:TEPRE1_RS05390
uniprot id: F4LSG5
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS08910
gene id: 1209989:TEPRE1_RS08910
uniprot id: F4LXB9
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

1209989:TEPRE1 RS00675
gene id: 1209989:TEPRE1_RS00675
uniprot id: F4LS81
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS07250
gene id: 1209989:TEPRE1_RS07250
uniprot id: F4LVK8
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1209989:TEPRE1 RS06935
gene id: 1209989:TEPRE1_RS06935
uniprot id: F4LV05
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1209989:TEPRE1 RS04140
gene id: 1209989:TEPRE1_RS04140
uniprot id: F4LX21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1209989:TEPRE1 RS07575
gene id: 1209989:TEPRE1_RS07575
uniprot id: F4LVZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1209989:TEPRE1 RS00225
gene id: 1209989:TEPRE1_RS00225
uniprot id: F4LRJ6
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

1209989:TEPRE1 RS09540
gene id: 1209989:TEPRE1_RS09540
uniprot id: F4LQP0
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.

1209989:TEPRE1 RS07385
gene id: 1209989:TEPRE1_RS07385
uniprot id: F4LVN5
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

1209989:TEPRE1 RS10845
gene id: 1209989:TEPRE1_RS10845
uniprot id: F4LRG0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS06975
gene id: 1209989:TEPRE1_RS06975
uniprot id: F4LV13
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1209989:TEPRE1 RS04355
gene id: 1209989:TEPRE1_RS04355
uniprot id: F4LXD6
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS05645
gene id: 1209989:TEPRE1_RS05645
uniprot id: F4LT13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1209989:TEPRE1 RS05925
gene id: 1209989:TEPRE1_RS05925
uniprot id: F4LTK3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1209989:TEPRE1 RS05600
gene id: 1209989:TEPRE1_RS05600
uniprot id: F4LT04
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

1209989:TEPRE1 RS08530
gene id: 1209989:TEPRE1_RS08530
uniprot id: F4LWX0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FBP aldolase/phosphatase family.
messages: Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
messages: Consists of a single catalytic domain, but remodels its active-site architecture via a large structural change to exhibit dual activities.
messages: Homooctamer; dimer of tetramers.

1209989:TEPRE1 RS12350
gene id: 1209989:TEPRE1_RS12350
uniprot id: F4LTX6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1209989:TEPRE1 RS08200
gene id: 1209989:TEPRE1_RS08200
uniprot id: F4LWQ7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1209989:TEPRE1 RS10165
gene id: 1209989:TEPRE1_RS10165
uniprot id: F4LR15
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS09370
gene id: 1209989:TEPRE1_RS09370
uniprot id: F4LQK6
names: Similarity
messages: Belongs to the manganese catalase family.

1209989:TEPRE1 RS09605
gene id: 1209989:TEPRE1_RS09605
uniprot id: F4LQQ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1209989:TEPRE1 RS12255
gene id: 1209989:TEPRE1_RS12255
uniprot id: L0S2W1
names: Similarity
messages: Belongs to the peptidase S16 family.

1209989:TEPRE1 RS06605
gene id: 1209989:TEPRE1_RS06605
uniprot id: F4LUD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1209989:TEPRE1 RS11380
gene id: 1209989:TEPRE1_RS11380
uniprot id: F4LSL3
names: Function
messages: Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase.

1209989:TEPRE1 RS08870
gene id: 1209989:TEPRE1_RS08870
uniprot id: F4LXB0
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS03220
gene id: 1209989:TEPRE1_RS03220
uniprot id: F4LW48
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1209989:TEPRE1 RS05900
gene id: 1209989:TEPRE1_RS05900
uniprot id: F4LTJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1209989:TEPRE1 RS05700
gene id: 1209989:TEPRE1_RS05700
uniprot id: F4LT24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1209989:TEPRE1 RS02235
gene id: 1209989:TEPRE1_RS02235
uniprot id: F4LUS7
names: Similarity
messages: Belongs to the UPF0597 family.

1209989:TEPRE1 RS04035
gene id: 1209989:TEPRE1_RS04035
uniprot id: F4LX02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1209989:TEPRE1 RS11395
gene id: 1209989:TEPRE1_RS11395
uniprot id: F4LSL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1209989:TEPRE1 RS06140
gene id: 1209989:TEPRE1_RS06140
uniprot id: F4LTP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1209989:TEPRE1 RS02545
gene id: 1209989:TEPRE1_RS02545
uniprot id: F4LVD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

1209989:TEPRE1 RS00020
gene id: 1209989:TEPRE1_RS00020
uniprot id: F4LR76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1209989:TEPRE1 RS03790
gene id: 1209989:TEPRE1_RS03790
uniprot id: F4LWM9
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1209989:TEPRE1 RS12355
gene id: 1209989:TEPRE1_RS12355
uniprot id: F4LTX7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

1209989:TEPRE1 RS08515
gene id: 1209989:TEPRE1_RS08515
uniprot id: F4LWW7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1209989:TEPRE1 RS03355
gene id: 1209989:TEPRE1_RS03355
uniprot id: F4LW73
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1209989:TEPRE1 RS05385
gene id: 1209989:TEPRE1_RS05385
uniprot id: F4LSG4
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1209989:TEPRE1 RS13190
gene id: 1209989:TEPRE1_RS13190
uniprot id: F4LV92
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1209989:TEPRE1 RS01530
gene id: 1209989:TEPRE1_RS01530
uniprot id: K7SGY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1209989:TEPRE1 RS04840
gene id: 1209989:TEPRE1_RS04840
uniprot id: F4LRQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1209989:TEPRE1 RS12470
gene id: 1209989:TEPRE1_RS12470
uniprot id: F4LUF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1209989:TEPRE1 RS06150
gene id: 1209989:TEPRE1_RS06150
uniprot id: F4LTP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1209989:TEPRE1 RS06760
gene id: 1209989:TEPRE1_RS06760
uniprot id: F4LUW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

1209989:TEPRE1 RS12315
gene id: 1209989:TEPRE1_RS12315
uniprot id: F4LTX0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1209989:TEPRE1 RS02205
gene id: 1209989:TEPRE1_RS02205
uniprot id: F4LUS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1209989:TEPRE1 RS12085
gene id: 1209989:TEPRE1_RS12085
uniprot id: F4LTS7
names: Similarity
messages: Belongs to the peptidase S14 family.

1209989:TEPRE1 RS11060
gene id: 1209989:TEPRE1_RS11060
uniprot id: F4LS01
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1209989:TEPRE1 RS10615
gene id: 1209989:TEPRE1_RS10615
uniprot id: F4LRC1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1209989:TEPRE1 RS02180
gene id: 1209989:TEPRE1_RS02180
uniprot id: F4LUR6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1209989:TEPRE1 RS01010
gene id: 1209989:TEPRE1_RS01010
uniprot id: F4LSU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1209989:TEPRE1 RS06980
gene id: 1209989:TEPRE1_RS06980
uniprot id: F4LV14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1209989:TEPRE1 RS00440
gene id: 1209989:TEPRE1_RS00440
uniprot id: F4LS37
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

1209989:TEPRE1 RS01545
gene id: 1209989:TEPRE1_RS01545
uniprot id: F4LTI0
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1209989:TEPRE1 RS11610
gene id: 1209989:TEPRE1_RS11610
uniprot id: F4LSQ7
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1209989:TEPRE1 RS05845
gene id: 1209989:TEPRE1_RS05845
uniprot id: F4LT47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1209989:TEPRE1 RS08565
gene id: 1209989:TEPRE1_RS08565
uniprot id: F4LX51
names: Caution
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS02540
gene id: 1209989:TEPRE1_RS02540
uniprot id: F4LVD0
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.

1209989:TEPRE1 RS11030
gene id: 1209989:TEPRE1_RS11030
uniprot id: F4LRZ5
names: Similarity
messages: Belongs to the FGGY kinase family.

1209989:TEPRE1 RS06120
gene id: 1209989:TEPRE1_RS06120
uniprot id: F4LTP2
names: Similarity
messages: Belongs to the FlgD family.

1209989:TEPRE1 RS10750
gene id: 1209989:TEPRE1_RS10750
uniprot id: F4LRE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1209989:TEPRE1 RS03820
gene id: 1209989:TEPRE1_RS03820
uniprot id: F4LWN5
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1209989:TEPRE1 RS08260
gene id: 1209989:TEPRE1_RS08260
uniprot id: F4LWR6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1209989:TEPRE1 RS04315
gene id: 1209989:TEPRE1_RS04315
uniprot id: F4LXC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1209989:TEPRE1 RS09860
gene id: 1209989:TEPRE1_RS09860
uniprot id: F4LQV3
names: Similarity
messages: Belongs to the sigma-54 factor family.

1209989:TEPRE1 RS07430
gene id: 1209989:TEPRE1_RS07430
uniprot id: F4LVW2
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1209989:TEPRE1 RS10595
gene id: 1209989:TEPRE1_RS10595
uniprot id: F4LRB7
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1209989:TEPRE1 RS08935
gene id: 1209989:TEPRE1_RS08935
uniprot id: F4LXJ4
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

1209989:TEPRE1 RS02485
gene id: 1209989:TEPRE1_RS02485
uniprot id: F4LVC0
names: Similarity
messages: Belongs to the class-I fumarase family.

1209989:TEPRE1 RS12395
gene id: 1209989:TEPRE1_RS12395
uniprot id: F4LTY5
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1209989:TEPRE1 RS01040
gene id: 1209989:TEPRE1_RS01040
uniprot id: F4LSV5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

1209989:TEPRE1 RS00980
gene id: 1209989:TEPRE1_RS00980
uniprot id: F4LSU3
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1209989:TEPRE1 RS00275
gene id: 1209989:TEPRE1_RS00275
uniprot id: F4LRK5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1209989:TEPRE1 RS03600
gene id: 1209989:TEPRE1_RS03600
uniprot id: F4LWJ1
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

1209989:TEPRE1 RS01160
gene id: 1209989:TEPRE1_RS01160
uniprot id: F4LSX9
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1209989:TEPRE1 RS02125
gene id: 1209989:TEPRE1_RS02125
uniprot id: F4LUQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1209989:TEPRE1 RS10425
gene id: 1209989:TEPRE1_RS10425
uniprot id: F4LR66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1209989:TEPRE1 RS07885
gene id: 1209989:TEPRE1_RS07885
uniprot id: F4LWC0
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS00105
gene id: 1209989:TEPRE1_RS00105
uniprot id: F4LRH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1209989:TEPRE1 RS11735
gene id: 1209989:TEPRE1_RS11735
uniprot id: F4LT66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

1209989:TEPRE1 RS09555
gene id: 1209989:TEPRE1_RS09555
uniprot id: F4LQP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1209989:TEPRE1 RS08730
gene id: 1209989:TEPRE1_RS08730
uniprot id: F4LX84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1209989:TEPRE1 RS09030
gene id: 1209989:TEPRE1_RS09030
uniprot id: F4LXL3
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS05970
gene id: 1209989:TEPRE1_RS05970
uniprot id: F4LTL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1209989:TEPRE1 RS09950
gene id: 1209989:TEPRE1_RS09950
uniprot id: F4LQX1
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS06590
gene id: 1209989:TEPRE1_RS06590
uniprot id: F4LUD6
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1209989:TEPRE1 RS04620
gene id: 1209989:TEPRE1_RS04620
uniprot id: F4LXI7
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1209989:TEPRE1 RS12625
gene id: 1209989:TEPRE1_RS12625
uniprot id: F4LUI1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1209989:TEPRE1 RS07700
gene id: 1209989:TEPRE1_RS07700
uniprot id: F4LW17
names: Similarity
messages: Belongs to the UPF0758 family.

1209989:TEPRE1 RS09920
gene id: 1209989:TEPRE1_RS09920
uniprot id: F4LQW5
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1209989:TEPRE1 RS09645
gene id: 1209989:TEPRE1_RS09645
uniprot id: F4LQR1
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1209989:TEPRE1 RS10295
gene id: 1209989:TEPRE1_RS10295
uniprot id: F4LR40
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1209989:TEPRE1 RS09890
gene id: 1209989:TEPRE1_RS09890
uniprot id: F4LQV9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS02555
gene id: 1209989:TEPRE1_RS02555
uniprot id: F4LVD3
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

1209989:TEPRE1 RS13330
gene id: 1209989:TEPRE1_RS13330
uniprot id: F4LRX8
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1209989:TEPRE1 RS12005
gene id: 1209989:TEPRE1_RS12005
uniprot id: F4LTA6
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS00570
gene id: 1209989:TEPRE1_RS00570
uniprot id: F4LS62
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate mutase GlmE subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS10940
gene id: 1209989:TEPRE1_RS10940
uniprot id: F4LRX6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.
messages: Homotetramer.

1209989:TEPRE1 RS09680
gene id: 1209989:TEPRE1_RS09680
uniprot id: F4LQR8
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1209989:TEPRE1 RS01350
gene id: 1209989:TEPRE1_RS01350
uniprot id: F4LTE2
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1209989:TEPRE1 RS00265
gene id: 1209989:TEPRE1_RS00265
uniprot id: F4LRK3
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1209989:TEPRE1 RS02265
gene id: 1209989:TEPRE1_RS02265
uniprot id: F4LUT3
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

1209989:TEPRE1 RS08080
gene id: 1209989:TEPRE1_RS08080
uniprot id: F4LWF9
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS02985
gene id: 1209989:TEPRE1_RS02985
uniprot id: F4LVT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1209989:TEPRE1 RS07285
gene id: 1209989:TEPRE1_RS07285
uniprot id: F4LVL5
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

1209989:TEPRE1 RS01950
gene id: 1209989:TEPRE1_RS01950
uniprot id: F4LU63
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS05490
gene id: 1209989:TEPRE1_RS05490
uniprot id: F4LSY2
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS02040
gene id: 1209989:TEPRE1_RS02040
uniprot id: F4LUN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1209989:TEPRE1 RS12505
gene id: 1209989:TEPRE1_RS12505
uniprot id: F4LUF8
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1209989:TEPRE1 RS01620
gene id: 1209989:TEPRE1_RS01620
uniprot id: F4LU00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Probably a homodimer.

1209989:TEPRE1 RS10910
gene id: 1209989:TEPRE1_RS10910
uniprot id: F4LRX0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1209989:TEPRE1 RS09650
gene id: 1209989:TEPRE1_RS09650
uniprot id: F4LQR2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1209989:TEPRE1 RS12560
gene id: 1209989:TEPRE1_RS12560
uniprot id: F4LUG9
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS05715
gene id: 1209989:TEPRE1_RS05715
uniprot id: F4LT27
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1209989:TEPRE1 RS07495
gene id: 1209989:TEPRE1_RS07495
uniprot id: F4LVX4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1209989:TEPRE1 RS00050
gene id: 1209989:TEPRE1_RS00050
uniprot id: F4LRG2
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1209989:TEPRE1 RS08040
gene id: 1209989:TEPRE1_RS08040
uniprot id: F4LWF1
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1209989:TEPRE1 RS06065
gene id: 1209989:TEPRE1_RS06065
uniprot id: F4LTN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor.

1209989:TEPRE1 RS05860
gene id: 1209989:TEPRE1_RS05860
uniprot id: F4LTI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1209989:TEPRE1 RS06955
gene id: 1209989:TEPRE1_RS06955
uniprot id: F4LV09
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS07725
gene id: 1209989:TEPRE1_RS07725
uniprot id: F4LW22
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1209989:TEPRE1 RS09955
gene id: 1209989:TEPRE1_RS09955
uniprot id: F4LQX2
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS09150
gene id: 1209989:TEPRE1_RS09150
uniprot id: F4LXN7
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1209989:TEPRE1 RS09810
gene id: 1209989:TEPRE1_RS09810
uniprot id: F4LQU3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

1209989:TEPRE1 RS08580
gene id: 1209989:TEPRE1_RS08580
uniprot id: F4LX54
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1209989:TEPRE1 RS03490
gene id: 1209989:TEPRE1_RS03490
uniprot id: F4LW94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

1209989:TEPRE1 RS08030
gene id: 1209989:TEPRE1_RS08030
uniprot id: F4LWE9
names: Similarity
messages: Belongs to the NadC/ModD family.

1209989:TEPRE1 RS03100
gene id: 1209989:TEPRE1_RS03100
uniprot id: F4LVV3
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1209989:TEPRE1 RS05710
gene id: 1209989:TEPRE1_RS05710
uniprot id: F4LT26
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1209989:TEPRE1 RS06300
gene id: 1209989:TEPRE1_RS06300
uniprot id: F4LU78
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1209989:TEPRE1 RS12380
gene id: 1209989:TEPRE1_RS12380
uniprot id: F4LTY2
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1209989:TEPRE1 RS05705
gene id: 1209989:TEPRE1_RS05705
uniprot id: F4LT25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U4 family.
messages: Cell membrane
messages: Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR.

1209989:TEPRE1 RS11750
gene id: 1209989:TEPRE1_RS11750
uniprot id: F4LT69
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1209989:TEPRE1 RS11845
gene id: 1209989:TEPRE1_RS11845
uniprot id: U4Q9M6
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS03150
gene id: 1209989:TEPRE1_RS03150
uniprot id: F4LW34
names: Similarity
messages: Belongs to the peptidase A24 family.

1209989:TEPRE1 RS09355
gene id: 1209989:TEPRE1_RS09355
uniprot id: F4LQK2
names: Similarity
names: Subunit
messages: Belongs to the beta-eliminating lyase family.
messages: Homotetramer.

1209989:TEPRE1 RS09385
gene id: 1209989:TEPRE1_RS09385
uniprot id: F4LQK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1209989:TEPRE1 RS12370
gene id: 1209989:TEPRE1_RS12370
uniprot id: F4LTY0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

1209989:TEPRE1 RS12130
gene id: 1209989:TEPRE1_RS12130
uniprot id: F4LTT5
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

1209989:TEPRE1 RS06435
gene id: 1209989:TEPRE1_RS06435
uniprot id: F4LUA5
names: Similarity
messages: Belongs to the CinA family.

1209989:TEPRE1 RS11265
gene id: 1209989:TEPRE1_RS11265
uniprot id: F4LSJ2
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

1209989:TEPRE1 RS05325
gene id: 1209989:TEPRE1_RS05325
uniprot id: F4LSF2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1209989:TEPRE1 RS08570
gene id: 1209989:TEPRE1_RS08570
uniprot id: F4LX52
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS08995
gene id: 1209989:TEPRE1_RS08995
uniprot id: F4LXK6
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1209989:TEPRE1 RS08600
gene id: 1209989:TEPRE1_RS08600
uniprot id: F4LX58
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

1209989:TEPRE1 RS03800
gene id: 1209989:TEPRE1_RS03800
uniprot id: F4LWN1
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

1209989:TEPRE1 RS12640
gene id: 1209989:TEPRE1_RS12640
uniprot id: F4LUI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1209989:TEPRE1 RS08650
gene id: 1209989:TEPRE1_RS08650
uniprot id: F4LX68
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1209989:TEPRE1 RS08445
gene id: 1209989:TEPRE1_RS08445
uniprot id: F4LWV3
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

1209989:TEPRE1 RS05955
gene id: 1209989:TEPRE1_RS05955
uniprot id: F4LTK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1209989:TEPRE1 RS06200
gene id: 1209989:TEPRE1_RS06200
uniprot id: F4LTQ8
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

1209989:TEPRE1 RS08050
gene id: 1209989:TEPRE1_RS08050
uniprot id: F4LWF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1209989:TEPRE1 RS09495
gene id: 1209989:TEPRE1_RS09495
uniprot id: F4LQN1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1209989:TEPRE1 RS06735
gene id: 1209989:TEPRE1_RS06735
uniprot id: F4LUW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1209989:TEPRE1 RS07105
gene id: 1209989:TEPRE1_RS07105
uniprot id: F4LVH9
names: Similarity
messages: Belongs to the GSP E family.

1209989:TEPRE1 RS12865
gene id: 1209989:TEPRE1_RS12865
uniprot id: F4LV30
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

1209989:TEPRE1 RS02500
gene id: 1209989:TEPRE1_RS02500
uniprot id: F4LVC2
names: Similarity
messages: Belongs to the EamA transporter family.

1209989:TEPRE1 RS05360
gene id: 1209989:TEPRE1_RS05360
uniprot id: F4LSF9
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1209989:TEPRE1 RS00165
gene id: 1209989:TEPRE1_RS00165
uniprot id: F4LRI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1209989:TEPRE1 RS13055
gene id: 1209989:TEPRE1_RS13055
uniprot id: F4LV65
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1209989:TEPRE1 RS13315
gene id: 1209989:TEPRE1_RS13315
uniprot id: U4QL35
names: Similarity
messages: Belongs to the 'phage' integrase family.

1209989:TEPRE1 RS02560
gene id: 1209989:TEPRE1_RS02560
uniprot id: F4LVD4
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

1209989:TEPRE1 RS10680
gene id: 1209989:TEPRE1_RS10680
uniprot id: F4LRD4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

1209989:TEPRE1 RS05555
gene id: 1209989:TEPRE1_RS05555
uniprot id: F4LSZ5
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1209989:TEPRE1 RS07655
gene id: 1209989:TEPRE1_RS07655
uniprot id: F4LW08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1209989:TEPRE1 RS12630
gene id: 1209989:TEPRE1_RS12630
uniprot id: F4LUI2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1209989:TEPRE1 RS12485
gene id: 1209989:TEPRE1_RS12485
uniprot id: F4LUF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1209989:TEPRE1 RS11285
gene id: 1209989:TEPRE1_RS11285
uniprot id: F4LSJ6
names: Similarity
messages: Belongs to the CitG/MdcB family.

1209989:TEPRE1 RS09460
gene id: 1209989:TEPRE1_RS09460
uniprot id: F4LQM4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1209989:TEPRE1 RS05000
gene id: 1209989:TEPRE1_RS05000
uniprot id: F4LRT4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1209989:TEPRE1 RS03795
gene id: 1209989:TEPRE1_RS03795
uniprot id: F4LWN0
names: Similarity
messages: Belongs to the PGI/PMI family.

1209989:TEPRE1 RS01670
gene id: 1209989:TEPRE1_RS01670
uniprot id: L0RZK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1209989:TEPRE1 RS08060
gene id: 1209989:TEPRE1_RS08060
uniprot id: F4LWF5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1209989:TEPRE1 RS12845
gene id: 1209989:TEPRE1_RS12845
uniprot id: F4LV26
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1209989:TEPRE1 RS07980
gene id: 1209989:TEPRE1_RS07980
uniprot id: F4LWE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

1209989:TEPRE1 RS07520
gene id: 1209989:TEPRE1_RS07520
uniprot id: F4LVX9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1209989:TEPRE1 RS00985
gene id: 1209989:TEPRE1_RS00985
uniprot id: F4LSU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1209989:TEPRE1 RS14065
gene id: 1209989:TEPRE1_RS14065
uniprot id: F4LQU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1209989:TEPRE1 RS07460
gene id: 1209989:TEPRE1_RS07460
uniprot id: F4LVW7
names: Similarity
messages: Belongs to the UPF0735 family.

1209989:TEPRE1 RS08690
gene id: 1209989:TEPRE1_RS08690
uniprot id: F4LX77
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1209989:TEPRE1 RS10280
gene id: 1209989:TEPRE1_RS10280
uniprot id: F4LR37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1209989:TEPRE1 RS11695
gene id: 1209989:TEPRE1_RS11695
uniprot id: F4LT58
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1209989:TEPRE1 RS11335
gene id: 1209989:TEPRE1_RS11335
uniprot id: F4LSK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CitD family.
messages: Covalent carrier of the coenzyme of citrate lyase.
messages: Cytoplasm
messages: Oligomer with a subunit composition of (alpha,beta,gamma)6.

1209989:TEPRE1 RS12195
gene id: 1209989:TEPRE1_RS12195
uniprot id: F4LTU7
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

1209989:TEPRE1 RS08930
gene id: 1209989:TEPRE1_RS08930
uniprot id: F4LXJ3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1209989:TEPRE1 RS02570
gene id: 1209989:TEPRE1_RS02570
uniprot id: F4LVD6
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

1209989:TEPRE1 RS08770
gene id: 1209989:TEPRE1_RS08770
uniprot id: F4LX90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

1209989:TEPRE1 RS00665
gene id: 1209989:TEPRE1_RS00665
uniprot id: F4LS79
names: Similarity
messages: Belongs to the manganese catalase family.

1209989:TEPRE1 RS02330
gene id: 1209989:TEPRE1_RS02330
uniprot id: F4LUU6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1209989:TEPRE1 RS11685
gene id: 1209989:TEPRE1_RS11685
uniprot id: F4LT56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1209989:TEPRE1 RS09930
gene id: 1209989:TEPRE1_RS09930
uniprot id: F4LQW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

1209989:TEPRE1 RS07985
gene id: 1209989:TEPRE1_RS07985
uniprot id: F4LWE1
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

1209989:TEPRE1 RS01365
gene id: 1209989:TEPRE1_RS01365
uniprot id: F4LTE5
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS03320
gene id: 1209989:TEPRE1_RS03320
uniprot id: F4LW67
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1209989:TEPRE1 RS10825
gene id: 1209989:TEPRE1_RS10825
uniprot id: F4LRF6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS12310
gene id: 1209989:TEPRE1_RS12310
uniprot id: F4LTW9
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS05975
gene id: 1209989:TEPRE1_RS05975
uniprot id: F4LTL3
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

1209989:TEPRE1 RS03535
gene id: 1209989:TEPRE1_RS03535
uniprot id: F4LWH8
names: Function
names: Similarity
names: Subunit
messages: Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha-keto acid in the first half-reaction.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1209989:TEPRE1 RS08110
gene id: 1209989:TEPRE1_RS08110
uniprot id: F4LWG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1209989:TEPRE1 RS05685
gene id: 1209989:TEPRE1_RS05685
uniprot id: F4LT21
names: Similarity
messages: Belongs to the UPF0749 family.

1209989:TEPRE1 RS07865
gene id: 1209989:TEPRE1_RS07865
uniprot id: F4LWB6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1209989:TEPRE1 RS13165
gene id: 1209989:TEPRE1_RS13165
uniprot id: F4LV87
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS07790
gene id: 1209989:TEPRE1_RS07790
uniprot id: F4LWA1
names: Similarity
messages: Belongs to the asp23 family.

1209989:TEPRE1 RS02285
gene id: 1209989:TEPRE1_RS02285
uniprot id: F4LUT7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1209989:TEPRE1 RS05450
gene id: 1209989:TEPRE1_RS05450
uniprot id: F4LSH7
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1209989:TEPRE1 RS10405
gene id: 1209989:TEPRE1_RS10405
uniprot id: F4LR62
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS12700
gene id: 1209989:TEPRE1_RS12700
uniprot id: F4LUJ6
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1209989:TEPRE1 RS07665
gene id: 1209989:TEPRE1_RS07665
uniprot id: F4LW10
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

1209989:TEPRE1 RS10035
gene id: 1209989:TEPRE1_RS10035
uniprot id: F4LQY9
names: Similarity
messages: Belongs to the creatininase superfamily.

1209989:TEPRE1 RS10740
gene id: 1209989:TEPRE1_RS10740
uniprot id: F4LRE3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1209989:TEPRE1 RS04200
gene id: 1209989:TEPRE1_RS04200
uniprot id: F4LX33
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

1209989:TEPRE1 RS01960
gene id: 1209989:TEPRE1_RS01960
uniprot id: F4LU65
names: Similarity
messages: Belongs to the leucine-binding protein family.

1209989:TEPRE1 RS07750
gene id: 1209989:TEPRE1_RS07750
uniprot id: F4LW25
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1209989:TEPRE1 RS10290
gene id: 1209989:TEPRE1_RS10290
uniprot id: F4LR39
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1209989:TEPRE1 RS08470
gene id: 1209989:TEPRE1_RS08470
uniprot id: F4LWV8
names: Subcellular Location Annotation
messages: Cytoplasm

1209989:TEPRE1 RS03580
gene id: 1209989:TEPRE1_RS03580
uniprot id: F4LWI7
names: Similarity
messages: Belongs to the UPF0342 family.

1209989:TEPRE1 RS03625
gene id: 1209989:TEPRE1_RS03625
uniprot id: F4LWJ6
names: Similarity
messages: Belongs to the pyruvate kinase family.

1209989:TEPRE1 RS01145
gene id: 1209989:TEPRE1_RS01145
uniprot id: F4LSX6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1209989:TEPRE1 RS01830
gene id: 1209989:TEPRE1_RS01830
uniprot id: F4LU41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1209989:TEPRE1 RS08830
gene id: 1209989:TEPRE1_RS08830
uniprot id: F4LXA2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1209989:TEPRE1 RS02340
gene id: 1209989:TEPRE1_RS02340
uniprot id: F4LUU8
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1209989:TEPRE1 RS12815
gene id: 1209989:TEPRE1_RS12815
uniprot id: F4LUM0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1209989:TEPRE1 RS01570
gene id: 1209989:TEPRE1_RS01570
uniprot id: F4LTI5
names: Similarity
messages: Belongs to the peptidase S8 family.

1209989:TEPRE1 RS04790
gene id: 1209989:TEPRE1_RS04790
uniprot id: F4LRP3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1209989:TEPRE1 RS11620
gene id: 1209989:TEPRE1_RS11620
uniprot id: F4LSQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1209989:TEPRE1 RS09215
gene id: 1209989:TEPRE1_RS09215
uniprot id: F4LXP9
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1209989:TEPRE1 RS11360
gene id: 1209989:TEPRE1_RS11360
uniprot id: F4LSK9
names: Similarity
messages: Belongs to the PrpF family.

1209989:TEPRE1 RS09670
gene id: 1209989:TEPRE1_RS09670
uniprot id: F4LQR6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS05625
gene id: 1209989:TEPRE1_RS05625
uniprot id: F4LT09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1209989:TEPRE1 RS13155
gene id: 1209989:TEPRE1_RS13155
uniprot id: F4LV85
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1209989:TEPRE1 RS09970
gene id: 1209989:TEPRE1_RS09970
uniprot id: F4LQX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diaminopimelate dehydrogenase family.
messages: Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.
messages: Homodimer.

1209989:TEPRE1 RS10505
gene id: 1209989:TEPRE1_RS10505
uniprot id: F4LR99
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1209989:TEPRE1 RS11085
gene id: 1209989:TEPRE1_RS11085
uniprot id: F4LS06
names: Similarity
messages: Belongs to the HsdR family.

1209989:TEPRE1 RS06720
gene id: 1209989:TEPRE1_RS06720
uniprot id: F4LUW1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS08010
gene id: 1209989:TEPRE1_RS08010
uniprot id: F4LWE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1209989:TEPRE1 RS08955
gene id: 1209989:TEPRE1_RS08955
uniprot id: F4LXJ8
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1209989:TEPRE1 RS02390
gene id: 1209989:TEPRE1_RS02390
uniprot id: F4LVA1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

1209989:TEPRE1 RS03610
gene id: 1209989:TEPRE1_RS03610
uniprot id: L0RZ18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Cytoplasm
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.

1209989:TEPRE1 RS03620
gene id: 1209989:TEPRE1_RS03620
uniprot id: F4LWJ5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS10925
gene id: 1209989:TEPRE1_RS10925
uniprot id: F4LRX3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1209989:TEPRE1 RS07210
gene id: 1209989:TEPRE1_RS07210
uniprot id: F4LVK0
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1209989:TEPRE1 RS06595
gene id: 1209989:TEPRE1_RS06595
uniprot id: F4LUD7
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1209989:TEPRE1 RS10155
gene id: 1209989:TEPRE1_RS10155
uniprot id: F4LR13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1209989:TEPRE1 RS02250
gene id: 1209989:TEPRE1_RS02250
uniprot id: F4LUT0
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

1209989:TEPRE1 RS06105
gene id: 1209989:TEPRE1_RS06105
uniprot id: F4LTN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

1209989:TEPRE1 RS12345
gene id: 1209989:TEPRE1_RS12345
uniprot id: F4LTX5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS10420
gene id: 1209989:TEPRE1_RS10420
uniprot id: F4LR65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1209989:TEPRE1 RS06020
gene id: 1209989:TEPRE1_RS06020
uniprot id: F4LTM2
names: Similarity
messages: Belongs to the UPF0102 family.

1209989:TEPRE1 RS11250
gene id: 1209989:TEPRE1_RS11250
uniprot id: F4LSI9
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1209989:TEPRE1 RS02895
gene id: 1209989:TEPRE1_RS02895
uniprot id: F4LVS2
names: Similarity
messages: Belongs to the UPF0047 family.

1209989:TEPRE1 RS08120
gene id: 1209989:TEPRE1_RS08120
uniprot id: F4LWG5
names: Similarity
messages: Belongs to the TrpF family.

1209989:TEPRE1 RS07215
gene id: 1209989:TEPRE1_RS07215
uniprot id: F4LVK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1209989:TEPRE1 RS11830
gene id: 1209989:TEPRE1_RS11830
uniprot id: U4Q9M7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1209989:TEPRE1 RS09590
gene id: 1209989:TEPRE1_RS09590
uniprot id: F4LQQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1209989:TEPRE1 RS07670
gene id: 1209989:TEPRE1_RS07670
uniprot id: F4LW11
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

1209989:TEPRE1 RS11420
gene id: 1209989:TEPRE1_RS11420
uniprot id: F4LSM1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1209989:TEPRE1 RS06840
gene id: 1209989:TEPRE1_RS06840
uniprot id: F4LUY5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS07425
gene id: 1209989:TEPRE1_RS07425
uniprot id: F4LVW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1209989:TEPRE1 RS10365
gene id: 1209989:TEPRE1_RS10365
uniprot id: F4LR54
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS11785
gene id: 1209989:TEPRE1_RS11785
uniprot id: F4LT76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1209989:TEPRE1 RS06905
gene id: 1209989:TEPRE1_RS06905
uniprot id: F4LUZ9
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.
messages: In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition.

1209989:TEPRE1 RS03855
gene id: 1209989:TEPRE1_RS03855
uniprot id: F4LWP1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1209989:TEPRE1 RS10485
gene id: 1209989:TEPRE1_RS10485
uniprot id: F4LR95
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS04360
gene id: 1209989:TEPRE1_RS04360
uniprot id: F4LXD7
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

1209989:TEPRE1 RS00005
gene id: 1209989:TEPRE1_RS00005
uniprot id: F4LR73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1209989:TEPRE1 RS00945
gene id: 1209989:TEPRE1_RS00945
uniprot id: F4LST6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1209989:TEPRE1 RS07115
gene id: 1209989:TEPRE1_RS07115
uniprot id: F4LVI1
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1209989:TEPRE1 RS06660
gene id: 1209989:TEPRE1_RS06660
uniprot id: F4LUV3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1209989:TEPRE1 RS01590
gene id: 1209989:TEPRE1_RS01590
uniprot id: F4LTZ4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS10745
gene id: 1209989:TEPRE1_RS10745
uniprot id: F4LRE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1209989:TEPRE1 RS03275
gene id: 1209989:TEPRE1_RS03275
uniprot id: F4LW59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1209989:TEPRE1 RS07255
gene id: 1209989:TEPRE1_RS07255
uniprot id: F4LVK9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS02585
gene id: 1209989:TEPRE1_RS02585
uniprot id: F4LVD9
names: Similarity
messages: Belongs to the class-I fumarase family.

1209989:TEPRE1 RS02260
gene id: 1209989:TEPRE1_RS02260
uniprot id: F4LUT2
names: Similarity
messages: Belongs to the CobH/CbiC family.

1209989:TEPRE1 RS03105
gene id: 1209989:TEPRE1_RS03105
uniprot id: F4LVV4
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1209989:TEPRE1 RS06715
gene id: 1209989:TEPRE1_RS06715
uniprot id: F4LUW0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

1209989:TEPRE1 RS04370
gene id: 1209989:TEPRE1_RS04370
uniprot id: F4LXD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1209989:TEPRE1 RS04980
gene id: 1209989:TEPRE1_RS04980
uniprot id: F4LRT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1209989:TEPRE1 RS00560
gene id: 1209989:TEPRE1_RS00560
uniprot id: F4LS60
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate mutase GlmS subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS07055
gene id: 1209989:TEPRE1_RS07055
uniprot id: F4LVG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1209989:TEPRE1 RS01520
gene id: 1209989:TEPRE1_RS01520
uniprot id: F4LTH5
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1209989:TEPRE1 RS03260
gene id: 1209989:TEPRE1_RS03260
uniprot id: F4LW56
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1209989:TEPRE1 RS03365
gene id: 1209989:TEPRE1_RS03365
uniprot id: F4LW75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1209989:TEPRE1 RS11900
gene id: 1209989:TEPRE1_RS11900
uniprot id: F4LT91
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

1209989:TEPRE1 RS09375
gene id: 1209989:TEPRE1_RS09375
uniprot id: F4LQK7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1209989:TEPRE1 RS07685
gene id: 1209989:TEPRE1_RS07685
uniprot id: F4LW14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1209989:TEPRE1 RS10345
gene id: 1209989:TEPRE1_RS10345
uniprot id: F4LR50
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

1209989:TEPRE1 RS09815
gene id: 1209989:TEPRE1_RS09815
uniprot id: F4LQU4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1209989:TEPRE1 RS08835
gene id: 1209989:TEPRE1_RS08835
uniprot id: F4LXA3
names: Similarity
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.

1209989:TEPRE1 RS07125
gene id: 1209989:TEPRE1_RS07125
uniprot id: F4LVI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1209989:TEPRE1 RS05665
gene id: 1209989:TEPRE1_RS05665
uniprot id: F4LT17
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS00350
gene id: 1209989:TEPRE1_RS00350
uniprot id: F4LRL9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS08490
gene id: 1209989:TEPRE1_RS08490
uniprot id: F4LWW2
names: Subcellular Location Annotation
messages: Cytoplasm

1209989:TEPRE1 RS08505
gene id: 1209989:TEPRE1_RS08505
uniprot id: F4LWW5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1209989:TEPRE1 RS06085
gene id: 1209989:TEPRE1_RS06085
uniprot id: F4LTN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

1209989:TEPRE1 RS13050
gene id: 1209989:TEPRE1_RS13050
uniprot id: F4LV64
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1209989:TEPRE1 RS09415
gene id: 1209989:TEPRE1_RS09415
uniprot id: F4LQL5
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1209989:TEPRE1 RS07500
gene id: 1209989:TEPRE1_RS07500
uniprot id: F4LVX5
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS11155
gene id: 1209989:TEPRE1_RS11155
uniprot id: F4LS21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1209989:TEPRE1 RS02870
gene id: 1209989:TEPRE1_RS02870
uniprot id: F4LVR7
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

1209989:TEPRE1 RS02940
gene id: 1209989:TEPRE1_RS02940
uniprot id: F4LVT1
names: Similarity
messages: Belongs to the CapA family.

1209989:TEPRE1 RS03965
gene id: 1209989:TEPRE1_RS03965
uniprot id: F4LWY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1209989:TEPRE1 RS10525
gene id: 1209989:TEPRE1_RS10525
uniprot id: F4LRA3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1209989:TEPRE1 RS12715
gene id: 1209989:TEPRE1_RS12715
uniprot id: F4LUJ9
names: Function
names: Similarity
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).

1209989:TEPRE1 RS00545
gene id: 1209989:TEPRE1_RS00545
uniprot id: F4LS58
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

1209989:TEPRE1 RS00550
gene id: 1209989:TEPRE1_RS00550
uniprot id: F4LS59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1209989:TEPRE1 RS08360
gene id: 1209989:TEPRE1_RS08360
uniprot id: F4LWT6
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

1209989:TEPRE1 RS07560
gene id: 1209989:TEPRE1_RS07560
uniprot id: F4LVY8
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1209989:TEPRE1 RS06675
gene id: 1209989:TEPRE1_RS06675
uniprot id: F4LUV6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1209989:TEPRE1 RS03910
gene id: 1209989:TEPRE1_RS03910
uniprot id: F4LWX7
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1209989:TEPRE1 RS08620
gene id: 1209989:TEPRE1_RS08620
uniprot id: F4LX62
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS02410
gene id: 1209989:TEPRE1_RS02410
uniprot id: F4LVA5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS01085
gene id: 1209989:TEPRE1_RS01085
uniprot id: F4LSW4
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1209989:TEPRE1 RS09935
gene id: 1209989:TEPRE1_RS09935
uniprot id: F4LQW8
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1209989:TEPRE1 RS07675
gene id: 1209989:TEPRE1_RS07675
uniprot id: F4LW12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

1209989:TEPRE1 RS05560
gene id: 1209989:TEPRE1_RS05560
uniprot id: F4LSZ6
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

1209989:TEPRE1 RS11365
gene id: 1209989:TEPRE1_RS11365
uniprot id: F4LSL0
names: Similarity
messages: Belongs to the PrpD family.

1209989:TEPRE1 RS07875
gene id: 1209989:TEPRE1_RS07875
uniprot id: F4LWB8
names: Function
names: Similarity
names: Subunit
messages: Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization.
messages: Belongs to the HutP family.
messages: Homohexamer.

1209989:TEPRE1 RS11790
gene id: 1209989:TEPRE1_RS11790
uniprot id: F4LT77
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1209989:TEPRE1 RS06035
gene id: 1209989:TEPRE1_RS06035
uniprot id: F4LTM5
names: Similarity
messages: Belongs to the DprA/Smf family.

1209989:TEPRE1 RS01900
gene id: 1209989:TEPRE1_RS01900
uniprot id: F4LU53
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS07475
gene id: 1209989:TEPRE1_RS07475
uniprot id: F4LVX0
names: Similarity
messages: Belongs to the peptidase S41A family.

1209989:TEPRE1 RS04595
gene id: 1209989:TEPRE1_RS04595
uniprot id: F4LXI0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1209989:TEPRE1 RS06845
gene id: 1209989:TEPRE1_RS06845
uniprot id: F4LUY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1209989:TEPRE1 RS01955
gene id: 1209989:TEPRE1_RS01955
uniprot id: F4LU64
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS02490
gene id: 1209989:TEPRE1_RS02490
uniprot id: F4LVC1
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1209989:TEPRE1 RS06320
gene id: 1209989:TEPRE1_RS06320
uniprot id: F4LU82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1209989:TEPRE1 RS10300
gene id: 1209989:TEPRE1_RS10300
uniprot id: F4LR41
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS09390
gene id: 1209989:TEPRE1_RS09390
uniprot id: F4LQL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1209989:TEPRE1 RS04985
gene id: 1209989:TEPRE1_RS04985
uniprot id: F4LRT1
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1209989:TEPRE1 RS03780
gene id: 1209989:TEPRE1_RS03780
uniprot id: F4LWM7
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

1209989:TEPRE1 RS08920
gene id: 1209989:TEPRE1_RS08920
uniprot id: F4LXC1
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS10515
gene id: 1209989:TEPRE1_RS10515
uniprot id: F4LRA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1209989:TEPRE1 RS06420
gene id: 1209989:TEPRE1_RS06420
uniprot id: F4LUA2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

1209989:TEPRE1 RS10250
gene id: 1209989:TEPRE1_RS10250
uniprot id: F4LR32
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS11765
gene id: 1209989:TEPRE1_RS11765
uniprot id: F4LT72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the encapsulin family. Family 1 subfamily.
messages: Encapsulin nanocompartment

1209989:TEPRE1 RS07275
gene id: 1209989:TEPRE1_RS07275
uniprot id: F4LVL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1209989:TEPRE1 RS05400
gene id: 1209989:TEPRE1_RS05400
uniprot id: F4LSG7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1209989:TEPRE1 RS08430
gene id: 1209989:TEPRE1_RS08430
uniprot id: F4LWV0
names: Function
names: Similarity
messages: Belongs to the LarC family.
messages: Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes.

1209989:TEPRE1 RS05990
gene id: 1209989:TEPRE1_RS05990
uniprot id: F4LTL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

1209989:TEPRE1 RS00825
gene id: 1209989:TEPRE1_RS00825
uniprot id: F4LSR2
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1209989:TEPRE1 RS05695
gene id: 1209989:TEPRE1_RS05695
uniprot id: F4LT23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1209989:TEPRE1 RS06015
gene id: 1209989:TEPRE1_RS06015
uniprot id: F4LTM1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1209989:TEPRE1 RS10395
gene id: 1209989:TEPRE1_RS10395
uniprot id: F4LR60
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. SigI subfamily.
messages: Cytoplasm
messages: Interacts with RsgI.
messages: Negatively regulated by the anti-sigma-I factor RsgI.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1209989:TEPRE1 RS08140
gene id: 1209989:TEPRE1_RS08140
uniprot id: F4LWG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1209989:TEPRE1 RS11950
gene id: 1209989:TEPRE1_RS11950
uniprot id: F4LT97
names: Similarity
messages: Belongs to the PemK/MazF family.

1209989:TEPRE1 RS10650
gene id: 1209989:TEPRE1_RS10650
uniprot id: F4LRC8
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1209989:TEPRE1 RS04895
gene id: 1209989:TEPRE1_RS04895
uniprot id: F4LRR3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1209989:TEPRE1 RS11325
gene id: 1209989:TEPRE1_RS11325
uniprot id: F4LSK2
names: Subcellular Location Annotation
messages: Cytoplasm

1209989:TEPRE1 RS08965
gene id: 1209989:TEPRE1_RS08965
uniprot id: F4LXK0
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1209989:TEPRE1 RS00915
gene id: 1209989:TEPRE1_RS00915
uniprot id: F4LST0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1209989:TEPRE1 RS00090
gene id: 1209989:TEPRE1_RS00090
uniprot id: F4LRH0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1209989:TEPRE1 RS12520
gene id: 1209989:TEPRE1_RS12520
uniprot id: F4LUG1
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1209989:TEPRE1 RS10045
gene id: 1209989:TEPRE1_RS10045
uniprot id: F4LQZ1
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS06075
gene id: 1209989:TEPRE1_RS06075
uniprot id: F4LTN3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1209989:TEPRE1 RS05675
gene id: 1209989:TEPRE1_RS05675
uniprot id: F4LT19
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS06990
gene id: 1209989:TEPRE1_RS06990
uniprot id: F4LV16
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1209989:TEPRE1 RS06305
gene id: 1209989:TEPRE1_RS06305
uniprot id: F4LU79
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1209989:TEPRE1 RS08145
gene id: 1209989:TEPRE1_RS08145
uniprot id: F4LWH1
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1209989:TEPRE1 RS10600
gene id: 1209989:TEPRE1_RS10600
uniprot id: F4LRB8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1209989:TEPRE1 RS12475
gene id: 1209989:TEPRE1_RS12475
uniprot id: F4LUF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1209989:TEPRE1 RS10620
gene id: 1209989:TEPRE1_RS10620
uniprot id: F4LRC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1209989:TEPRE1 RS05940
gene id: 1209989:TEPRE1_RS05940
uniprot id: F4LTK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1209989:TEPRE1 RS12455
gene id: 1209989:TEPRE1_RS12455
uniprot id: F4LUE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1209989:TEPRE1 RS12260
gene id: 1209989:TEPRE1_RS12260
uniprot id: F4LTV9
names: Similarity
messages: Belongs to the FemABX family.

1209989:TEPRE1 RS01395
gene id: 1209989:TEPRE1_RS01395
uniprot id: F4LTF0
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS02845
gene id: 1209989:TEPRE1_RS02845
uniprot id: F4LVR2
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

1209989:TEPRE1 RS03940
gene id: 1209989:TEPRE1_RS03940
uniprot id: F4LWY3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

1209989:TEPRE1 RS08865
gene id: 1209989:TEPRE1_RS08865
uniprot id: F4LXA9
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1209989:TEPRE1 RS00405
gene id: 1209989:TEPRE1_RS00405
uniprot id: F4LRN0
names: Similarity
messages: Belongs to the peptidase S1 family.

1209989:TEPRE1 RS03010
gene id: 1209989:TEPRE1_RS03010
uniprot id: F4LVU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1209989:TEPRE1 RS05890
gene id: 1209989:TEPRE1_RS05890
uniprot id: F4LTJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1209989:TEPRE1 RS04090
gene id: 1209989:TEPRE1_RS04090
uniprot id: F4LX13
names: Subcellular Location Annotation
messages: Cytoplasm

1209989:TEPRE1 RS05760
gene id: 1209989:TEPRE1_RS05760
uniprot id: F4LT36
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1209989:TEPRE1 RS05050
gene id: 1209989:TEPRE1_RS05050
uniprot id: F4LRU4
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1209989:TEPRE1 RS06070
gene id: 1209989:TEPRE1_RS06070
uniprot id: F4LTN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1209989:TEPRE1 RS09180
gene id: 1209989:TEPRE1_RS09180
uniprot id: F4LXP3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1209989:TEPRE1 RS05340
gene id: 1209989:TEPRE1_RS05340
uniprot id: F4LSF5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1209989:TEPRE1 RS06370
gene id: 1209989:TEPRE1_RS06370
uniprot id: F4LU92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1209989:TEPRE1 RS06650
gene id: 1209989:TEPRE1_RS06650
uniprot id: F4LUV0
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1209989:TEPRE1 RS10215
gene id: 1209989:TEPRE1_RS10215
uniprot id: F4LR25
names: Similarity
messages: Belongs to the FGGY kinase family.

1209989:TEPRE1 RS12905
gene id: 1209989:TEPRE1_RS12905
uniprot id: F4LV39
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1209989:TEPRE1 RS06180
gene id: 1209989:TEPRE1_RS06180
uniprot id: F4LTQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1209989:TEPRE1 RS05875
gene id: 1209989:TEPRE1_RS05875
uniprot id: F4LTJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1209989:TEPRE1 RS02025
gene id: 1209989:TEPRE1_RS02025
uniprot id: F4LUN6
names: Similarity
messages: Belongs to the PrpF family.

1209989:TEPRE1 RS09010
gene id: 1209989:TEPRE1_RS09010
uniprot id: F4LXK9
names: Similarity
messages: Belongs to the DapA family.

1209989:TEPRE1 RS01425
gene id: 1209989:TEPRE1_RS01425
uniprot id: F4LTF6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1209989:TEPRE1 RS02055
gene id: 1209989:TEPRE1_RS02055
uniprot id: F4LUP2
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.

1209989:TEPRE1 RS03885
gene id: 1209989:TEPRE1_RS03885
uniprot id: F4LWP8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1209989:TEPRE1 RS01695
gene id: 1209989:TEPRE1_RS01695
uniprot id: F4LU15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1209989:TEPRE1 RS06835
gene id: 1209989:TEPRE1_RS06835
uniprot id: F4LUY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

1209989:TEPRE1 RS02335
gene id: 1209989:TEPRE1_RS02335
uniprot id: F4LUU7
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS12495
gene id: 1209989:TEPRE1_RS12495
uniprot id: F4LUF6
names: Caution
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1209989:TEPRE1 RS11010
gene id: 1209989:TEPRE1_RS11010
uniprot id: F4LRZ1
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS05920
gene id: 1209989:TEPRE1_RS05920
uniprot id: F4LTK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1209989:TEPRE1 RS10360
gene id: 1209989:TEPRE1_RS10360
uniprot id: F4LR53
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1209989:TEPRE1 RS02400
gene id: 1209989:TEPRE1_RS02400
uniprot id: F4LVA3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1209989:TEPRE1 RS01870
gene id: 1209989:TEPRE1_RS01870
uniprot id: F4LU47
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

1209989:TEPRE1 RS05835
gene id: 1209989:TEPRE1_RS05835
uniprot id: F4LT45
names: Similarity
messages: Belongs to the IMPACT family.

1209989:TEPRE1 RS09640
gene id: 1209989:TEPRE1_RS09640
uniprot id: F4LQR0
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1209989:TEPRE1 RS09430
gene id: 1209989:TEPRE1_RS09430
uniprot id: F4LQL8
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1209989:TEPRE1 RS00730
gene id: 1209989:TEPRE1_RS00730
uniprot id: F4LS93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

1209989:TEPRE1 RS08875
gene id: 1209989:TEPRE1_RS08875
uniprot id: F4LXB1
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS01360
gene id: 1209989:TEPRE1_RS01360
uniprot id: F4LTE4
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS06130
gene id: 1209989:TEPRE1_RS06130
uniprot id: L0RYH8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1209989:TEPRE1 RS11015
gene id: 1209989:TEPRE1_RS11015
uniprot id: F4LRZ2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

1209989:TEPRE1 RS00085
gene id: 1209989:TEPRE1_RS00085
uniprot id: F4LRG9
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1209989:TEPRE1 RS01380
gene id: 1209989:TEPRE1_RS01380
uniprot id: F4LTE8
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1209989:TEPRE1 RS03745
gene id: 1209989:TEPRE1_RS03745
uniprot id: F4LWM0
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

1209989:TEPRE1 RS03545
gene id: 1209989:TEPRE1_RS03545
uniprot id: F4LWI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1209989:TEPRE1 RS03140
gene id: 1209989:TEPRE1_RS03140
uniprot id: F4LW32
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1209989:TEPRE1 RS06525
gene id: 1209989:TEPRE1_RS06525
uniprot id: F4LUC3
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1209989:TEPRE1 RS10495
gene id: 1209989:TEPRE1_RS10495
uniprot id: F4LR97
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1209989:TEPRE1 RS02190
gene id: 1209989:TEPRE1_RS02190
uniprot id: F4LUR8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1209989:TEPRE1 RS04935
gene id: 1209989:TEPRE1_RS04935
uniprot id: F4LRS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1209989:TEPRE1 RS04915
gene id: 1209989:TEPRE1_RS04915
uniprot id: F4LRR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1209989:TEPRE1 RS08410
gene id: 1209989:TEPRE1_RS08410
uniprot id: F4LWU6
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1209989:TEPRE1 RS11090
gene id: 1209989:TEPRE1_RS11090
uniprot id: F4LS07
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1209989:TEPRE1 RS12500
gene id: 1209989:TEPRE1_RS12500
uniprot id: F4LUF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1209989:TEPRE1 RS10010
gene id: 1209989:TEPRE1_RS10010
uniprot id: F4LQY4
names: Similarity
messages: Belongs to the UPF0340 family.

1209989:TEPRE1 RS12750
gene id: 1209989:TEPRE1_RS12750
uniprot id: F4LUK7
names: Similarity
messages: Belongs to the Nth/MutY family.

1209989:TEPRE1 RS09290
gene id: 1209989:TEPRE1_RS09290
uniprot id: U4QL53
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1209989:TEPRE1 RS03425
gene id: 1209989:TEPRE1_RS03425
uniprot id: F4LW80
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS07550
gene id: 1209989:TEPRE1_RS07550
uniprot id: F4LVY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1209989:TEPRE1 RS10105
gene id: 1209989:TEPRE1_RS10105
uniprot id: F4LR03
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS05495
gene id: 1209989:TEPRE1_RS05495
uniprot id: F4LSY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.

1209989:TEPRE1 RS09910
gene id: 1209989:TEPRE1_RS09910
uniprot id: F4LQW3
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

1209989:TEPRE1 RS10265
gene id: 1209989:TEPRE1_RS10265
uniprot id: F4LR34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1209989:TEPRE1 RS05375
gene id: 1209989:TEPRE1_RS05375
uniprot id: F4LSG2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1209989:TEPRE1 RS12705
gene id: 1209989:TEPRE1_RS12705
uniprot id: F4LUJ7
names: Similarity
messages: Belongs to the EamA transporter family.

1209989:TEPRE1 RS00515
gene id: 1209989:TEPRE1_RS00515
uniprot id: F4LS52
names: Similarity
messages: Belongs to the Fur family.

1209989:TEPRE1 RS01435
gene id: 1209989:TEPRE1_RS01435
uniprot id: F4LTF8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1209989:TEPRE1 RS00510
gene id: 1209989:TEPRE1_RS00510
uniprot id: F4LS51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1209989:TEPRE1 RS11930
gene id: 1209989:TEPRE1_RS11930
uniprot id: F4LT95
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

1209989:TEPRE1 RS00445
gene id: 1209989:TEPRE1_RS00445
uniprot id: F4LS38
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

1209989:TEPRE1 RS00260
gene id: 1209989:TEPRE1_RS00260
uniprot id: F4LRK2
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1209989:TEPRE1 RS12730
gene id: 1209989:TEPRE1_RS12730
uniprot id: F4LUK2
names: Similarity
messages: Belongs to the UPF0597 family.

1209989:TEPRE1 RS05460
gene id: 1209989:TEPRE1_RS05460
uniprot id: F4LSH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1209989:TEPRE1 RS06635
gene id: 1209989:TEPRE1_RS06635
uniprot id: F4LUE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1209989:TEPRE1 RS01355
gene id: 1209989:TEPRE1_RS01355
uniprot id: F4LTE3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1209989:TEPRE1 RS00975
gene id: 1209989:TEPRE1_RS00975
uniprot id: F4LSU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1209989:TEPRE1 RS05335
gene id: 1209989:TEPRE1_RS05335
uniprot id: F4LSF4
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1209989:TEPRE1 RS10890
gene id: 1209989:TEPRE1_RS10890
uniprot id: F4LRW6
names: Similarity
messages: Belongs to the CtsR family.

1209989:TEPRE1 RS04330
gene id: 1209989:TEPRE1_RS04330
uniprot id: F4LXD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1209989:TEPRE1 RS04885
gene id: 1209989:TEPRE1_RS04885
uniprot id: F4LRR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Membrane

1209989:TEPRE1 RS12280
gene id: 1209989:TEPRE1_RS12280
uniprot id: F4LTW3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1209989:TEPRE1 RS10775
gene id: 1209989:TEPRE1_RS10775
uniprot id: F4LRF0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1209989:TEPRE1 RS06195
gene id: 1209989:TEPRE1_RS06195
uniprot id: F4LTQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1209989:TEPRE1 RS10630
gene id: 1209989:TEPRE1_RS10630
uniprot id: F4LRC4
names: Similarity
messages: Belongs to the CdaR family.

1209989:TEPRE1 RS08585
gene id: 1209989:TEPRE1_RS08585
uniprot id: F4LX55
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS02305
gene id: 1209989:TEPRE1_RS02305
uniprot id: F4LUU1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1209989:TEPRE1 RS06000
gene id: 1209989:TEPRE1_RS06000
uniprot id: F4LTL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1209989:TEPRE1 RS03785
gene id: 1209989:TEPRE1_RS03785
uniprot id: F4LWM8
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1209989:TEPRE1 RS09665
gene id: 1209989:TEPRE1_RS09665
uniprot id: F4LQR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1209989:TEPRE1 RS01390
gene id: 1209989:TEPRE1_RS01390
uniprot id: F4LTE9
names: Similarity
messages: Belongs to the DEAD box helicase family.

1209989:TEPRE1 RS07925
gene id: 1209989:TEPRE1_RS07925
uniprot id: F4LWC8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1209989:TEPRE1 RS10755
gene id: 1209989:TEPRE1_RS10755
uniprot id: F4LRE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1209989:TEPRE1 RS12820
gene id: 1209989:TEPRE1_RS12820
uniprot id: F4LUM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

1209989:TEPRE1 RS03525
gene id: 1209989:TEPRE1_RS03525
uniprot id: F4LWH6
names: Similarity
messages: Belongs to the PGI/PMI family.

1209989:TEPRE1 RS07300
gene id: 1209989:TEPRE1_RS07300
uniprot id: F4LVL8
names: Similarity
messages: Belongs to the asp23 family.

1209989:TEPRE1 RS07690
gene id: 1209989:TEPRE1_RS07690
uniprot id: F4LW15
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1209989:TEPRE1 RS08480
gene id: 1209989:TEPRE1_RS08480
uniprot id: F4LWW0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1209989:TEPRE1 RS05430
gene id: 1209989:TEPRE1_RS05430
uniprot id: F4LSH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1209989:TEPRE1 RS13070
gene id: 1209989:TEPRE1_RS13070
uniprot id: F4LV68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1209989:TEPRE1 RS05635
gene id: 1209989:TEPRE1_RS05635
uniprot id: F4LT11
names: Similarity
messages: Belongs to the transpeptidase family.

1209989:TEPRE1 RS02800
gene id: 1209989:TEPRE1_RS02800
uniprot id: F4LVQ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1209989:TEPRE1 RS02480
gene id: 1209989:TEPRE1_RS02480
uniprot id: F4LVB9
names: Similarity
messages: Belongs to the class-I fumarase family.

1209989:TEPRE1 RS10930
gene id: 1209989:TEPRE1_RS10930
uniprot id: F4LRX4
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

1209989:TEPRE1 RS04350
gene id: 1209989:TEPRE1_RS04350
uniprot id: F4LXD5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family. L-methionine gamma-lyase subfamily.

1209989:TEPRE1 RS01245
gene id: 1209989:TEPRE1_RS01245
uniprot id: F4LTC5
names: Similarity
messages: Belongs to the UPF0251 family.

1209989:TEPRE1 RS05765
gene id: 1209989:TEPRE1_RS05765
uniprot id: F4LT37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1209989:TEPRE1 RS10080
gene id: 1209989:TEPRE1_RS10080
uniprot id: F4LQZ7
names: Similarity
messages: Belongs to the peptidase C56 family.

1209989:TEPRE1 RS11035
gene id: 1209989:TEPRE1_RS11035
uniprot id: F4LRZ6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS05640
gene id: 1209989:TEPRE1_RS05640
uniprot id: F4LT12
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS03480
gene id: 1209989:TEPRE1_RS03480
uniprot id: F4LW92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

1209989:TEPRE1 RS06915
gene id: 1209989:TEPRE1_RS06915
uniprot id: F4LV01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1209989:TEPRE1 RS04940
gene id: 1209989:TEPRE1_RS04940
uniprot id: F4LRS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1209989:TEPRE1 RS08290
gene id: 1209989:TEPRE1_RS08290
uniprot id: F4LWS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

1209989:TEPRE1 RS05525
gene id: 1209989:TEPRE1_RS05525
uniprot id: F4LSY9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1209989:TEPRE1 RS05770
gene id: 1209989:TEPRE1_RS05770
uniprot id: F4LT38
names: Function
names: Subcellular Location Annotation
messages: ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
messages: Cytoplasm

1209989:TEPRE1 RS06910
gene id: 1209989:TEPRE1_RS06910
uniprot id: F4LV00
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1209989:TEPRE1 RS03570
gene id: 1209989:TEPRE1_RS03570
uniprot id: F4LWI5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1209989:TEPRE1 RS04195
gene id: 1209989:TEPRE1_RS04195
uniprot id: F4LX32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1209989:TEPRE1 RS04215
gene id: 1209989:TEPRE1_RS04215
uniprot id: F4LX35
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1209989:TEPRE1 RS07825
gene id: 1209989:TEPRE1_RS07825
uniprot id: F4LWA8
names: Cofactor
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Binds 1 Mg(2+) ion per subunit.

1209989:TEPRE1 RS02470
gene id: 1209989:TEPRE1_RS02470
uniprot id: F4LVB7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1209989:TEPRE1 RS08475
gene id: 1209989:TEPRE1_RS08475
uniprot id: F4LWV9
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS02280
gene id: 1209989:TEPRE1_RS02280
uniprot id: F4LUT6
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1209989:TEPRE1 RS00495
gene id: 1209989:TEPRE1_RS00495
uniprot id: F4LS48
names: Similarity
messages: Belongs to the thioredoxin family.

1209989:TEPRE1 RS08810
gene id: 1209989:TEPRE1_RS08810
uniprot id: F4LX98
names: Similarity
messages: Belongs to the FemABX family.

1209989:TEPRE1 RS05935
gene id: 1209989:TEPRE1_RS05935
uniprot id: F4LTK5
names: Similarity
messages: Belongs to the fabD family.

1209989:TEPRE1 RS10320
gene id: 1209989:TEPRE1_RS10320
uniprot id: F4LR45
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS07375
gene id: 1209989:TEPRE1_RS07375
uniprot id: F4LVN3
names: Similarity
messages: Belongs to the RemA family.

1209989:TEPRE1 RS08170
gene id: 1209989:TEPRE1_RS08170
uniprot id: F4LWQ2
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1209989:TEPRE1 RS04075
gene id: 1209989:TEPRE1_RS04075
uniprot id: F4LX10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1209989:TEPRE1 RS05455
gene id: 1209989:TEPRE1_RS05455
uniprot id: F4LSH8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1209989:TEPRE1 RS06365
gene id: 1209989:TEPRE1_RS06365
uniprot id: F4LU91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1209989:TEPRE1 RS08300
gene id: 1209989:TEPRE1_RS08300
uniprot id: F4LWS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1209989:TEPRE1 RS10855
gene id: 1209989:TEPRE1_RS10855
uniprot id: F4LRV9
names: Similarity
messages: Belongs to the ycf81 family.

1209989:TEPRE1 RS07360
gene id: 1209989:TEPRE1_RS07360
uniprot id: F4LVN0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS00240
gene id: 1209989:TEPRE1_RS00240
uniprot id: F4LRJ9
names: Similarity
messages: Belongs to the DSD1 family.

1209989:TEPRE1 RS08710
gene id: 1209989:TEPRE1_RS08710
uniprot id: F4LX81
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS14000
gene id: 1209989:TEPRE1_RS14000
uniprot id: F4LVT5
names: Similarity
messages: Belongs to the UPF0236 family.

1209989:TEPRE1 RS10695
gene id: 1209989:TEPRE1_RS10695
uniprot id: F4LRD7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1209989:TEPRE1 RS00040
gene id: 1209989:TEPRE1_RS00040
uniprot id: F4LR80
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1209989:TEPRE1 RS00095
gene id: 1209989:TEPRE1_RS00095
uniprot id: F4LRH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1209989:TEPRE1 RS03715
gene id: 1209989:TEPRE1_RS03715
uniprot id: F4LWL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

1209989:TEPRE1 RS01800
gene id: 1209989:TEPRE1_RS01800
uniprot id: F4LU35
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1209989:TEPRE1 RS09155
gene id: 1209989:TEPRE1_RS09155
uniprot id: F4LXN8
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1209989:TEPRE1 RS03015
gene id: 1209989:TEPRE1_RS03015
uniprot id: F4LVU3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1209989:TEPRE1 RS10470
gene id: 1209989:TEPRE1_RS10470
uniprot id: F4LR92
names: Function
names: Similarity
messages: Belongs to the NanE family.
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

1209989:TEPRE1 RS05345
gene id: 1209989:TEPRE1_RS05345
uniprot id: F4LSF6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1209989:TEPRE1 RS06360
gene id: 1209989:TEPRE1_RS06360
uniprot id: F4LU90
names: Similarity
messages: Belongs to the ribF family.

1209989:TEPRE1 RS03810
gene id: 1209989:TEPRE1_RS03810
uniprot id: F4LWN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Galactose/methyl galactoside importer (TC 3.A.1.2.3) family.
messages: Cell membrane
messages: Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system.
messages: The complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

1209989:TEPRE1 RS05550
gene id: 1209989:TEPRE1_RS05550
uniprot id: F4LSZ4
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

1209989:TEPRE1 RS05440
gene id: 1209989:TEPRE1_RS05440
uniprot id: F4LSH5
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

1209989:TEPRE1 RS02590
gene id: 1209989:TEPRE1_RS02590
uniprot id: F4LVE0
names: Similarity
messages: Belongs to the class-I fumarase family.

1209989:TEPRE1 RS01735
gene id: 1209989:TEPRE1_RS01735
uniprot id: F4LU22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1209989:TEPRE1 RS03465
gene id: 1209989:TEPRE1_RS03465
uniprot id: F4LW89
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1209989:TEPRE1 RS02310
gene id: 1209989:TEPRE1_RS02310
uniprot id: F4LUU2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1209989:TEPRE1 RS02740
gene id: 1209989:TEPRE1_RS02740
uniprot id: K7SWE7
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1209989:TEPRE1 RS10040
gene id: 1209989:TEPRE1_RS10040
uniprot id: F4LQZ0
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.

1209989:TEPRE1 RS09995
gene id: 1209989:TEPRE1_RS09995
uniprot id: F4LQY0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1209989:TEPRE1 RS05530
gene id: 1209989:TEPRE1_RS05530
uniprot id: F4LSZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

1209989:TEPRE1 RS03495
gene id: 1209989:TEPRE1_RS03495
uniprot id: F4LW95
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1209989:TEPRE1 RS10785
gene id: 1209989:TEPRE1_RS10785
uniprot id: F4LRF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1209989:TEPRE1 RS03555
gene id: 1209989:TEPRE1_RS03555
uniprot id: F4LWI2
names: Similarity
messages: Belongs to the histone deacetylase family.

1209989:TEPRE1 RS12680
gene id: 1209989:TEPRE1_RS12680
uniprot id: F4LUJ2
names: Subcellular Location Annotation
messages: Cytoplasm

1209989:TEPRE1 RS05885
gene id: 1209989:TEPRE1_RS05885
uniprot id: F4LTJ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1209989:TEPRE1 RS09075
gene id: 1209989:TEPRE1_RS09075
uniprot id: F4LXM2
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS03925
gene id: 1209989:TEPRE1_RS03925
uniprot id: F4LWY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1209989:TEPRE1 RS07335
gene id: 1209989:TEPRE1_RS07335
uniprot id: F4LVM5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1209989:TEPRE1 RS05945
gene id: 1209989:TEPRE1_RS05945
uniprot id: F4LTK7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1209989:TEPRE1 RS12655
gene id: 1209989:TEPRE1_RS12655
uniprot id: F4LUI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1209989:TEPRE1 RS07205
gene id: 1209989:TEPRE1_RS07205
uniprot id: F4LVJ9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1209989:TEPRE1 RS07365
gene id: 1209989:TEPRE1_RS07365
uniprot id: F4LVN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1209989:TEPRE1 RS04095
gene id: 1209989:TEPRE1_RS04095
uniprot id: F4LX14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1209989:TEPRE1 RS11100
gene id: 1209989:TEPRE1_RS11100
uniprot id: F4LS09
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1209989:TEPRE1 RS13185
gene id: 1209989:TEPRE1_RS13185
uniprot id: F4LV91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1209989:TEPRE1 RS10670
gene id: 1209989:TEPRE1_RS10670
uniprot id: F4LRD2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1209989:TEPRE1 RS09800
gene id: 1209989:TEPRE1_RS09800
uniprot id: F4LQU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1209989:TEPRE1 RS09505
gene id: 1209989:TEPRE1_RS09505
uniprot id: F4LQN3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1209989:TEPRE1 RS08820
gene id: 1209989:TEPRE1_RS08820
uniprot id: F4LXA0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1209989:TEPRE1 RS00200
gene id: 1209989:TEPRE1_RS00200
uniprot id: F4LRJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1209989:TEPRE1 RS06290
gene id: 1209989:TEPRE1_RS06290
uniprot id: F4LU76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1209989:TEPRE1 RS12785
gene id: 1209989:TEPRE1_RS12785
uniprot id: F4LUL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1209989:TEPRE1 RS06190
gene id: 1209989:TEPRE1_RS06190
uniprot id: F4LTQ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1209989:TEPRE1 RS09655
gene id: 1209989:TEPRE1_RS09655
uniprot id: F4LQR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1209989:TEPRE1 RS09105
gene id: 1209989:TEPRE1_RS09105
uniprot id: F4LXM8
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.

1209989:TEPRE1 RS05790
gene id: 1209989:TEPRE1_RS05790
uniprot id: F4LT42
names: Similarity
messages: Belongs to the peptidase S58 family.

1209989:TEPRE1 RS08330
gene id: 1209989:TEPRE1_RS08330
uniprot id: F4LWT0
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1209989:TEPRE1 RS03175
gene id: 1209989:TEPRE1_RS03175
uniprot id: F4LW39
names: Similarity
messages: Belongs to the GSP E family.

1209989:TEPRE1 RS03265
gene id: 1209989:TEPRE1_RS03265
uniprot id: F4LW57
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1209989:TEPRE1 RS08960
gene id: 1209989:TEPRE1_RS08960
uniprot id: F4LXJ9
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1209989:TEPRE1 RS08160
gene id: 1209989:TEPRE1_RS08160
uniprot id: F4LWQ0
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

1209989:TEPRE1 RS04180
gene id: 1209989:TEPRE1_RS04180
uniprot id: F4LX29
names: Similarity
messages: Belongs to the bacterial flagellin family.

1209989:TEPRE1 RS00970
gene id: 1209989:TEPRE1_RS00970
uniprot id: F4LSU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1209989:TEPRE1 RS07775
gene id: 1209989:TEPRE1_RS07775
uniprot id: F4LW28
names: Similarity
names: Subunit
messages: Belongs to the PdxA family. PdxA2 subfamily.
messages: Homodimer.

1209989:TEPRE1 RS08130
gene id: 1209989:TEPRE1_RS08130
uniprot id: F4LWG7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS13160
gene id: 1209989:TEPRE1_RS13160
uniprot id: F4LV86
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1209989:TEPRE1 RS01115
gene id: 1209989:TEPRE1_RS01115
uniprot id: F4LSX0
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1209989:TEPRE1 RS07535
gene id: 1209989:TEPRE1_RS07535
uniprot id: F4LVY2
names: Caution
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS01865
gene id: 1209989:TEPRE1_RS01865
uniprot id: F4LU46
names: Similarity
messages: Belongs to the asp23 family.

1209989:TEPRE1 RS00310
gene id: 1209989:TEPRE1_RS00310
uniprot id: F4LRL1
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

1209989:TEPRE1 RS02200
gene id: 1209989:TEPRE1_RS02200
uniprot id: F4LUS0
names: Similarity
messages: Belongs to the FGGY kinase family.

1209989:TEPRE1 RS08990
gene id: 1209989:TEPRE1_RS08990
uniprot id: F4LXK5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1209989:TEPRE1 RS07100
gene id: 1209989:TEPRE1_RS07100
uniprot id: F4LVH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

1209989:TEPRE1 RS02900
gene id: 1209989:TEPRE1_RS02900
uniprot id: F4LVS3
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

1209989:TEPRE1 RS00355
gene id: 1209989:TEPRE1_RS00355
uniprot id: F4LRM0
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

1209989:TEPRE1 RS05445
gene id: 1209989:TEPRE1_RS05445
uniprot id: F4LSH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1209989:TEPRE1 RS10945
gene id: 1209989:TEPRE1_RS10945
uniprot id: F4LRX7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1209989:TEPRE1 RS06950
gene id: 1209989:TEPRE1_RS06950
uniprot id: F4LV08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1209989:TEPRE1 RS01540
gene id: 1209989:TEPRE1_RS01540
uniprot id: F4LTH9
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1209989:TEPRE1 RS07545
gene id: 1209989:TEPRE1_RS07545
uniprot id: F4LVY4
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1209989:TEPRE1 RS01035
gene id: 1209989:TEPRE1_RS01035
uniprot id: F4LSV4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1209989:TEPRE1 RS05980
gene id: 1209989:TEPRE1_RS05980
uniprot id: F4LTL4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1209989:TEPRE1 RS11710
gene id: 1209989:TEPRE1_RS11710
uniprot id: F4LT61
names: Similarity
names: Subunit
messages: Belongs to the beta-eliminating lyase family.
messages: Homotetramer.

1209989:TEPRE1 RS06160
gene id: 1209989:TEPRE1_RS06160
uniprot id: F4LTQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

1209989:TEPRE1 RS07830
gene id: 1209989:TEPRE1_RS07830
uniprot id: F4LWA9
names: Similarity
messages: Belongs to the hexokinase family.

1209989:TEPRE1 RS04150
gene id: 1209989:TEPRE1_RS04150
uniprot id: F4LX23
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS09400
gene id: 1209989:TEPRE1_RS09400
uniprot id: F4LQL2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1209989:TEPRE1 RS09205
gene id: 1209989:TEPRE1_RS09205
uniprot id: F4LXP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1209989:TEPRE1 RS12295
gene id: 1209989:TEPRE1_RS12295
uniprot id: F4LTW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1209989:TEPRE1 RS12665
gene id: 1209989:TEPRE1_RS12665
uniprot id: F4LUI9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1209989:TEPRE1 RS12810
gene id: 1209989:TEPRE1_RS12810
uniprot id: F4LUL9
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1209989:TEPRE1 RS05365
gene id: 1209989:TEPRE1_RS05365
uniprot id: F4LSG0
names: Similarity
messages: Belongs to the GARS family.

1209989:TEPRE1 RS03930
gene id: 1209989:TEPRE1_RS03930
uniprot id: F4LWY1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS12320
gene id: 1209989:TEPRE1_RS12320
uniprot id: F4LTX1
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1209989:TEPRE1 RS03585
gene id: 1209989:TEPRE1_RS03585
uniprot id: F4LWI8
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

1209989:TEPRE1 RS07815
gene id: 1209989:TEPRE1_RS07815
uniprot id: F4LWA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1209989:TEPRE1 RS09675
gene id: 1209989:TEPRE1_RS09675
uniprot id: F4LQR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1209989:TEPRE1 RS10455
gene id: 1209989:TEPRE1_RS10455
uniprot id: F4LR72
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1209989:TEPRE1 RS13175
gene id: 1209989:TEPRE1_RS13175
uniprot id: F4LV89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

1209989:TEPRE1 RS11995
gene id: 1209989:TEPRE1_RS11995
uniprot id: F4LTA4
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1209989:TEPRE1 RS10450
gene id: 1209989:TEPRE1_RS10450
uniprot id: F4LR71
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1209989:TEPRE1 RS05150
gene id: 1209989:TEPRE1_RS05150
uniprot id: F4LSB8
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS07680
gene id: 1209989:TEPRE1_RS07680
uniprot id: F4LW13
names: Similarity
messages: Belongs to the transpeptidase family.

1209989:TEPRE1 RS12590
gene id: 1209989:TEPRE1_RS12590
uniprot id: F4LUH5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS12585
gene id: 1209989:TEPRE1_RS12585
uniprot id: F4LUH4
names: Similarity
messages: Belongs to the glycosyl hydrolase 8 (cellulase D) family.

1209989:TEPRE1 RS07770
gene id: 1209989:TEPRE1_RS07770
uniprot id: F4LW27
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1209989:TEPRE1 RS00805
gene id: 1209989:TEPRE1_RS00805
uniprot id: F4LSA8
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: In the native structure, TdcB is in a dimeric form, whereas in the TdcB-AMP complex, it exists in a tetrameric form (dimer of dimers).

1209989:TEPRE1 RS01020
gene id: 1209989:TEPRE1_RS01020
uniprot id: F4LSV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1209989:TEPRE1 RS09880
gene id: 1209989:TEPRE1_RS09880
uniprot id: F4LQV7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS10735
gene id: 1209989:TEPRE1_RS10735
uniprot id: F4LRE2
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

1209989:TEPRE1 RS05630
gene id: 1209989:TEPRE1_RS05630
uniprot id: F4LT10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsL family.
messages: Cell membrane
messages: Essential cell division protein.
messages: Membrane

1209989:TEPRE1 RS00375
gene id: 1209989:TEPRE1_RS00375
uniprot id: F4LRM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1209989:TEPRE1 RS01485
gene id: 1209989:TEPRE1_RS01485
uniprot id: F4LTG8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1209989:TEPRE1 RS03070
gene id: 1209989:TEPRE1_RS03070
uniprot id: F4LVU7
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1209989:TEPRE1 RS01015
gene id: 1209989:TEPRE1_RS01015
uniprot id: F4LSV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1209989:TEPRE1 RS12375
gene id: 1209989:TEPRE1_RS12375
uniprot id: F4LTY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1209989:TEPRE1 RS02575
gene id: 1209989:TEPRE1_RS02575
uniprot id: F4LVD7
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1209989:TEPRE1 RS08055
gene id: 1209989:TEPRE1_RS08055
uniprot id: F4LWF4
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

1209989:TEPRE1 RS07395
gene id: 1209989:TEPRE1_RS07395
uniprot id: F4LVN7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1209989:TEPRE1 RS09260
gene id: 1209989:TEPRE1_RS09260
uniprot id: L0S0M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1209989:TEPRE1 RS01305
gene id: 1209989:TEPRE1_RS01305
uniprot id: F4LTD5
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1209989:TEPRE1 RS09125
gene id: 1209989:TEPRE1_RS09125
uniprot id: F4LXN2
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS06895
gene id: 1209989:TEPRE1_RS06895
uniprot id: F4LUZ7
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1209989:TEPRE1 RS12265
gene id: 1209989:TEPRE1_RS12265
uniprot id: F4LTW0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1209989:TEPRE1 RS01970
gene id: 1209989:TEPRE1_RS01970
uniprot id: F4LUM5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1209989:TEPRE1 RS04910
gene id: 1209989:TEPRE1_RS04910
uniprot id: F4LRR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1209989:TEPRE1 RS02360
gene id: 1209989:TEPRE1_RS02360
uniprot id: F4LV95
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1209989:TEPRE1 RS03360
gene id: 1209989:TEPRE1_RS03360
uniprot id: F4LW74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1209989:TEPRE1 RS07220
gene id: 1209989:TEPRE1_RS07220
uniprot id: F4LVK2
names: Similarity
messages: Belongs to the RecJ family.

1209989:TEPRE1 RS03075
gene id: 1209989:TEPRE1_RS03075
uniprot id: F4LVU8
names: Similarity
messages: Belongs to the peptidase S16 family.

1209989:TEPRE1 RS08155
gene id: 1209989:TEPRE1_RS08155
uniprot id: F4LWH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1209989:TEPRE1 RS07370
gene id: 1209989:TEPRE1_RS07370
uniprot id: F4LVN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1209989:TEPRE1 RS09405
gene id: 1209989:TEPRE1_RS09405
uniprot id: F4LQL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

1209989:TEPRE1 RS06235
gene id: 1209989:TEPRE1_RS06235
uniprot id: F4LTR5
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1209989:TEPRE1 RS10340
gene id: 1209989:TEPRE1_RS10340
uniprot id: F4LR49
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

1209989:TEPRE1 RS03440
gene id: 1209989:TEPRE1_RS03440
uniprot id: F4LW83
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1209989:TEPRE1 RS09330
gene id: 1209989:TEPRE1_RS09330
uniprot id: F4LQJ7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1209989:TEPRE1 RS10370
gene id: 1209989:TEPRE1_RS10370
uniprot id: F4LR55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

1209989:TEPRE1 RS11355
gene id: 1209989:TEPRE1_RS11355
uniprot id: F4LSK8
names: Similarity
messages: Belongs to the PrpF family.

1209989:TEPRE1 RS12460
gene id: 1209989:TEPRE1_RS12460
uniprot id: F4LUE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1209989:TEPRE1 RS00845
gene id: 1209989:TEPRE1_RS00845
uniprot id: F4LSR6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1209989:TEPRE1 RS12690
gene id: 1209989:TEPRE1_RS12690
uniprot id: F4LUJ4
names: Subcellular Location Annotation
messages: Membrane

1209989:TEPRE1 RS06850
gene id: 1209989:TEPRE1_RS06850
uniprot id: F4LUY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1209989:TEPRE1 RS08525
gene id: 1209989:TEPRE1_RS08525
uniprot id: F4LWW9
names: Similarity
messages: Belongs to the arginase family.

1209989:TEPRE1 RS06280
gene id: 1209989:TEPRE1_RS06280
uniprot id: F4LU74
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.