1197717:BED41 RS15500
gene id: 1197717:BED41_RS15500
uniprot id: A0A1B2I8U7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1197717:BED41 RS04630
gene id: 1197717:BED41_RS04630
uniprot id: A0A1B2I393
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1197717:BED41 RS00725
gene id: 1197717:BED41_RS00725
uniprot id: A0A1B2I1A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1197717:BED41 RS10275
gene id: 1197717:BED41_RS10275
uniprot id: A0A1B2I628
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1197717:BED41 RS08060
gene id: 1197717:BED41_RS08060
uniprot id: A0A1B2I518
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1197717:BED41 RS08055
gene id: 1197717:BED41_RS08055
uniprot id: A0A1B2I501
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1197717:BED41 RS13110
gene id: 1197717:BED41_RS13110
uniprot id: A0A1B2I7J5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1197717:BED41 RS08975
gene id: 1197717:BED41_RS08975
uniprot id: A0A1B2I5E3
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

1197717:BED41 RS02530
gene id: 1197717:BED41_RS02530
uniprot id: A0A1B2I297
names: Similarity
messages: Belongs to the carbamate kinase family.

1197717:BED41 RS15810
gene id: 1197717:BED41_RS15810
uniprot id: A0A1B2I901
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1197717:BED41 RS06840
gene id: 1197717:BED41_RS06840
uniprot id: A0A1B2I4F9
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1197717:BED41 RS14580
gene id: 1197717:BED41_RS14580
uniprot id: A0A1B2I8A8
names: Similarity
messages: Belongs to the peptidase C59 family.

1197717:BED41 RS02705
gene id: 1197717:BED41_RS02705
uniprot id: A0A1B2I2A5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1197717:BED41 RS15005
gene id: 1197717:BED41_RS15005
uniprot id: A0A1B2I8J6
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS09660
gene id: 1197717:BED41_RS09660
uniprot id: A0A1B2I5Q5
names: Similarity
messages: Belongs to the Skp family.

1197717:BED41 RS10830
gene id: 1197717:BED41_RS10830
uniprot id: A0A1B2I6B6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1197717:BED41 RS01520
gene id: 1197717:BED41_RS01520
uniprot id: A0A1B2I1P4
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

1197717:BED41 RS10660
gene id: 1197717:BED41_RS10660
uniprot id: A0A1B2I680
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

1197717:BED41 RS02955
gene id: 1197717:BED41_RS02955
uniprot id: A0A1B2I2F3
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS05120
gene id: 1197717:BED41_RS05120
uniprot id: A0A1B2I3L3
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1197717:BED41 RS07030
gene id: 1197717:BED41_RS07030
uniprot id: A0A1B2I4I3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS13585
gene id: 1197717:BED41_RS13585
uniprot id: A0A1B2I7T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1197717:BED41 RS05080
gene id: 1197717:BED41_RS05080
uniprot id: A0A1B2I3F5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1197717:BED41 RS03615
gene id: 1197717:BED41_RS03615
uniprot id: A0A1B2I2T9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1197717:BED41 RS04515
gene id: 1197717:BED41_RS04515
uniprot id: A0A1B2I354
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

1197717:BED41 RS12140
gene id: 1197717:BED41_RS12140
uniprot id: A0A1B2I720
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1197717:BED41 RS09930
gene id: 1197717:BED41_RS09930
uniprot id: A0A1B2I5X2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1197717:BED41 RS06105
gene id: 1197717:BED41_RS06105
uniprot id: A0A1B2I3Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1197717:BED41 RS12635
gene id: 1197717:BED41_RS12635
uniprot id: A0A1B2I7B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

1197717:BED41 RS11485
gene id: 1197717:BED41_RS11485
uniprot id: A0A1B2I6P2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1197717:BED41 RS03640
gene id: 1197717:BED41_RS03640
uniprot id: A0A1B2I2Q9
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1197717:BED41 RS07755
gene id: 1197717:BED41_RS07755
uniprot id: A0A1B2I4T1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS07475
gene id: 1197717:BED41_RS07475
uniprot id: A0A1B2I4R6
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1197717:BED41 RS01865
gene id: 1197717:BED41_RS01865
uniprot id: A0A1B2I1Y2
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1197717:BED41 RS07585
gene id: 1197717:BED41_RS07585
uniprot id: A0A1B2I4Q7
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1197717:BED41 RS15985
gene id: 1197717:BED41_RS15985
uniprot id: A0A1B2I903
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1197717:BED41 RS00215
gene id: 1197717:BED41_RS00215
uniprot id: A0A1B2I150
names: Similarity
messages: Belongs to the SUI1 family.

1197717:BED41 RS16005
gene id: 1197717:BED41_RS16005
uniprot id: A0A1B2I936
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS02090
gene id: 1197717:BED41_RS02090
uniprot id: A0A1B2I1Z2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1197717:BED41 RS00970
gene id: 1197717:BED41_RS00970
uniprot id: A0A1B2I1I3
names: Similarity
messages: Belongs to the UPF0597 family.

1197717:BED41 RS02715
gene id: 1197717:BED41_RS02715
uniprot id: A0A1B2I291
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1197717:BED41 RS12265
gene id: 1197717:BED41_RS12265
uniprot id: A0A1B2I775
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1197717:BED41 RS05040
gene id: 1197717:BED41_RS05040
uniprot id: A0A1B2I3H9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1197717:BED41 RS06740
gene id: 1197717:BED41_RS06740
uniprot id: A0A1B2I4A5
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1197717:BED41 RS05305
gene id: 1197717:BED41_RS05305
uniprot id: A0A1B2I3L2
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS08425
gene id: 1197717:BED41_RS08425
uniprot id: A0A1B2I548
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1197717:BED41 RS05315
gene id: 1197717:BED41_RS05315
uniprot id: A0A1B2I3K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1197717:BED41 RS09020
gene id: 1197717:BED41_RS09020
uniprot id: A0A1B2I5F4
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

1197717:BED41 RS13215
gene id: 1197717:BED41_RS13215
uniprot id: A0A1B2I7L7
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1197717:BED41 RS07655
gene id: 1197717:BED41_RS07655
uniprot id: A0A1B2I4Q8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1197717:BED41 RS05145
gene id: 1197717:BED41_RS05145
uniprot id: A0A1B2I3H4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1197717:BED41 RS15920
gene id: 1197717:BED41_RS15920
uniprot id: A0A1B2I8Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1197717:BED41 RS12370
gene id: 1197717:BED41_RS12370
uniprot id: A0A1B2I753
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1197717:BED41 RS12540
gene id: 1197717:BED41_RS12540
uniprot id: A0A1B2I788
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

1197717:BED41 RS12960
gene id: 1197717:BED41_RS12960
uniprot id: A0A1B2I7G4
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1197717:BED41 RS15605
gene id: 1197717:BED41_RS15605
uniprot id: A0A1B2I8U2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1197717:BED41 RS06080
gene id: 1197717:BED41_RS06080
uniprot id: A0A1B2I3Z1
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

1197717:BED41 RS12735
gene id: 1197717:BED41_RS12735
uniprot id: A0A1B2I7E4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1197717:BED41 RS14610
gene id: 1197717:BED41_RS14610
uniprot id: A0A1B2I8B9
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

1197717:BED41 RS14950
gene id: 1197717:BED41_RS14950
uniprot id: A0A1B2I8I7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1197717:BED41 RS06045
gene id: 1197717:BED41_RS06045
uniprot id: A0A1B2I3X7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1197717:BED41 RS01960
gene id: 1197717:BED41_RS01960
uniprot id: A0A1B2I1W7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1197717:BED41 RS06615
gene id: 1197717:BED41_RS06615
uniprot id: A0A1B2I4A3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1197717:BED41 RS10775
gene id: 1197717:BED41_RS10775
uniprot id: A0A1B2I6C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1197717:BED41 RS07700
gene id: 1197717:BED41_RS07700
uniprot id: A0A1B2I4R8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1197717:BED41 RS03265
gene id: 1197717:BED41_RS03265
uniprot id: A0A1B2I2L2
names: Similarity
messages: Belongs to the IlvD/Edd family.

1197717:BED41 RS00995
gene id: 1197717:BED41_RS00995
uniprot id: A0A1B2I1F2
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1197717:BED41 RS05860
gene id: 1197717:BED41_RS05860
uniprot id: A0A1B2I3Z0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1197717:BED41 RS11925
gene id: 1197717:BED41_RS11925
uniprot id: A0A1B2I6Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1197717:BED41 RS00510
gene id: 1197717:BED41_RS00510
uniprot id: A0A1B2I174
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

1197717:BED41 RS05985
gene id: 1197717:BED41_RS05985
uniprot id: A0A1B2I3W8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS15440
gene id: 1197717:BED41_RS15440
uniprot id: A0A1B2I8U3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1197717:BED41 RS04540
gene id: 1197717:BED41_RS04540
uniprot id: A0A1B2I375
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1197717:BED41 RS00030
gene id: 1197717:BED41_RS00030
uniprot id: A0A1B2I101
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

1197717:BED41 RS09940
gene id: 1197717:BED41_RS09940
uniprot id: A0A1B2I5V2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1197717:BED41 RS06545
gene id: 1197717:BED41_RS06545
uniprot id: A0A1B2I4A2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1197717:BED41 RS04705
gene id: 1197717:BED41_RS04705
uniprot id: A0A1B2I3A7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS13545
gene id: 1197717:BED41_RS13545
uniprot id: A0A1B2I7W5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1197717:BED41 RS07080
gene id: 1197717:BED41_RS07080
uniprot id: A0A1B2I4H8
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS13220
gene id: 1197717:BED41_RS13220
uniprot id: A0A1B2I7N0
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS02930
gene id: 1197717:BED41_RS02930
uniprot id: A0A1B2I2D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1197717:BED41 RS13265
gene id: 1197717:BED41_RS13265
uniprot id: A0A1B2I7M7
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1197717:BED41 RS10700
gene id: 1197717:BED41_RS10700
uniprot id: A0A1B2I697
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1197717:BED41 RS05580
gene id: 1197717:BED41_RS05580
uniprot id: A0A1B2I3P8
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS00575
gene id: 1197717:BED41_RS00575
uniprot id: A0A1B2I187
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1197717:BED41 RS08310
gene id: 1197717:BED41_RS08310
uniprot id: A0A1B2I530
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1197717:BED41 RS08580
gene id: 1197717:BED41_RS08580
uniprot id: A0A1B2I577
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Membrane

1197717:BED41 RS09640
gene id: 1197717:BED41_RS09640
uniprot id: A0A1B2I5Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1197717:BED41 RS03735
gene id: 1197717:BED41_RS03735
uniprot id: A0A1B2I2T7
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS15510
gene id: 1197717:BED41_RS15510
uniprot id: A0A1B2I8W6
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS02745
gene id: 1197717:BED41_RS02745
uniprot id: A0A1B2I2A0
names: Similarity
messages: Belongs to the peptidase C59 family.

1197717:BED41 RS02495
gene id: 1197717:BED41_RS02495
uniprot id: A0A1B2I265
names: Subcellular Location Annotation
messages: Cytoplasm

1197717:BED41 RS01925
gene id: 1197717:BED41_RS01925
uniprot id: A0A1B2I1V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1197717:BED41 RS04290
gene id: 1197717:BED41_RS04290
uniprot id: A0A1B2I322
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1197717:BED41 RS00160
gene id: 1197717:BED41_RS00160
uniprot id: A0A1B2I136
names: Function
names: Similarity
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.

1197717:BED41 RS04340
gene id: 1197717:BED41_RS04340
uniprot id: A0A1B2I329
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

1197717:BED41 RS11475
gene id: 1197717:BED41_RS11475
uniprot id: A0A1B2I6P8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1197717:BED41 RS01090
gene id: 1197717:BED41_RS01090
uniprot id: A0A1B2I1G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1197717:BED41 RS09770
gene id: 1197717:BED41_RS09770
uniprot id: A0A1B2I5U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

1197717:BED41 RS07130
gene id: 1197717:BED41_RS07130
uniprot id: A0A1B2I9F0
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1197717:BED41 RS01555
gene id: 1197717:BED41_RS01555
uniprot id: A0A1B2I1N5
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1197717:BED41 RS06705
gene id: 1197717:BED41_RS06705
uniprot id: A0A1B2I4A7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1197717:BED41 RS12015
gene id: 1197717:BED41_RS12015
uniprot id: A0A1B2I6Z5
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1197717:BED41 RS12445
gene id: 1197717:BED41_RS12445
uniprot id: A0A1B2I793
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS02840
gene id: 1197717:BED41_RS02840
uniprot id: A0A1B2I2C4
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS08380
gene id: 1197717:BED41_RS08380
uniprot id: A0A1B2I546
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS09800
gene id: 1197717:BED41_RS09800
uniprot id: A0A1B2I5U9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1197717:BED41 RS15845
gene id: 1197717:BED41_RS15845
uniprot id: A0A1B2I907
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS01045
gene id: 1197717:BED41_RS01045
uniprot id: A0A1B2I1G4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1197717:BED41 RS02945
gene id: 1197717:BED41_RS02945
uniprot id: A0A1B2I2E0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1197717:BED41 RS06735
gene id: 1197717:BED41_RS06735
uniprot id: A0A1B2I4A8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1197717:BED41 RS14270
gene id: 1197717:BED41_RS14270
uniprot id: A0A1B2I873
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homotetramer.

1197717:BED41 RS02040
gene id: 1197717:BED41_RS02040
uniprot id: A0A1B2I1Y0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1197717:BED41 RS02830
gene id: 1197717:BED41_RS02830
uniprot id: A0A1B2I2B9
names: Similarity
messages: Belongs to the CFA/CMAS family.

1197717:BED41 RS05660
gene id: 1197717:BED41_RS05660
uniprot id: A0A1B2I3S8
names: Function
names: Similarity
messages: Belongs to the vsr family.
messages: May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.

1197717:BED41 RS06760
gene id: 1197717:BED41_RS06760
uniprot id: A0A1B2I4B8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1197717:BED41 RS09840
gene id: 1197717:BED41_RS09840
uniprot id: A0A1B2I5U7
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1197717:BED41 RS03820
gene id: 1197717:BED41_RS03820
uniprot id: A0A1B2I2U3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1197717:BED41 RS00090
gene id: 1197717:BED41_RS00090
uniprot id: A0A1B2I0Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

1197717:BED41 RS01860
gene id: 1197717:BED41_RS01860
uniprot id: A0A1B2I1W1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS13255
gene id: 1197717:BED41_RS13255
uniprot id: A0A1B2I7M3
names: Caution
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1197717:BED41 RS05905
gene id: 1197717:BED41_RS05905
uniprot id: A0A1B2I3W1
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.

1197717:BED41 RS05130
gene id: 1197717:BED41_RS05130
uniprot id: A0A1B2I3G7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1197717:BED41 RS08010
gene id: 1197717:BED41_RS08010
uniprot id: A0A1B2I513
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1197717:BED41 RS07390
gene id: 1197717:BED41_RS07390
uniprot id: A0A1B2I4K8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1197717:BED41 RS09130
gene id: 1197717:BED41_RS09130
uniprot id: A0A1B2I5I3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1197717:BED41 RS09670
gene id: 1197717:BED41_RS09670
uniprot id: A0A1B2I5Q6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1197717:BED41 RS05455
gene id: 1197717:BED41_RS05455
uniprot id: A0A1B2I3S4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1197717:BED41 RS08525
gene id: 1197717:BED41_RS08525
uniprot id: A0A1B2I588
names: Similarity
messages: Belongs to the CtsR family.

1197717:BED41 RS07050
gene id: 1197717:BED41_RS07050
uniprot id: A0A1B2I4F4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1197717:BED41 RS14820
gene id: 1197717:BED41_RS14820
uniprot id: A0A1B2I8H0
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1197717:BED41 RS07675
gene id: 1197717:BED41_RS07675
uniprot id: A0A1B2I4U2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1197717:BED41 RS07935
gene id: 1197717:BED41_RS07935
uniprot id: A0A1B2I4W9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS11135
gene id: 1197717:BED41_RS11135
uniprot id: A0A1B2I6I2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1197717:BED41 RS04135
gene id: 1197717:BED41_RS04135
uniprot id: A0A1B2I2Z7
names: Subcellular Location Annotation
messages: Bacterial microcompartment

1197717:BED41 RS02065
gene id: 1197717:BED41_RS02065
uniprot id: A0A1B2I1Z4
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

1197717:BED41 RS05625
gene id: 1197717:BED41_RS05625
uniprot id: A0A1B2I9D6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

1197717:BED41 RS09915
gene id: 1197717:BED41_RS09915
uniprot id: A0A1B2I5X8
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

1197717:BED41 RS08670
gene id: 1197717:BED41_RS08670
uniprot id: A0A1B2I5A3
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

1197717:BED41 RS02050
gene id: 1197717:BED41_RS02050
uniprot id: A0A1B2I1Z1
names: Subcellular Location Annotation
messages: Cytoplasm

1197717:BED41 RS13160
gene id: 1197717:BED41_RS13160
uniprot id: A0A1B2I7K7
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

1197717:BED41 RS07695
gene id: 1197717:BED41_RS07695
uniprot id: A0A1B2I4V9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1197717:BED41 RS12760
gene id: 1197717:BED41_RS12760
uniprot id: A0A1B2I7D0
names: Similarity
messages: Belongs to the leucine-binding protein family.

1197717:BED41 RS10740
gene id: 1197717:BED41_RS10740
uniprot id: A0A1B2I6D2
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1197717:BED41 RS10885
gene id: 1197717:BED41_RS10885
uniprot id: A0A1B2I6C4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1197717:BED41 RS06580
gene id: 1197717:BED41_RS06580
uniprot id: A0A1B2I4C3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1197717:BED41 RS01675
gene id: 1197717:BED41_RS01675
uniprot id: A0A1B2I1Q9
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1197717:BED41 RS06935
gene id: 1197717:BED41_RS06935
uniprot id: A0A1B2I4E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1197717:BED41 RS06575
gene id: 1197717:BED41_RS06575
uniprot id: A0A1B2I499
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1197717:BED41 RS12135
gene id: 1197717:BED41_RS12135
uniprot id: A0A1B2I721
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS13455
gene id: 1197717:BED41_RS13455
uniprot id: A0A1B2I7R5
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS04165
gene id: 1197717:BED41_RS04165
uniprot id: A0A1B2I331
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

1197717:BED41 RS14635
gene id: 1197717:BED41_RS14635
uniprot id: A0A1B2I8D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1197717:BED41 RS07965
gene id: 1197717:BED41_RS07965
uniprot id: A0A1B2I4X7
names: Similarity
messages: Belongs to the arginine deiminase family.

1197717:BED41 RS15790
gene id: 1197717:BED41_RS15790
uniprot id: A0A1B2I8Z5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1197717:BED41 RS02635
gene id: 1197717:BED41_RS02635
uniprot id: A0A1B2I284
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1197717:BED41 RS11145
gene id: 1197717:BED41_RS11145
uniprot id: A0A1B2I6J5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1197717:BED41 RS01870
gene id: 1197717:BED41_RS01870
uniprot id: A0A1B2I1U6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1197717:BED41 RS10210
gene id: 1197717:BED41_RS10210
uniprot id: A0A1B2I604
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.

1197717:BED41 RS07740
gene id: 1197717:BED41_RS07740
uniprot id: A0A1B2I4T6
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1197717:BED41 RS05070
gene id: 1197717:BED41_RS05070
uniprot id: A0A1B2I8Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1197717:BED41 RS11130
gene id: 1197717:BED41_RS11130
uniprot id: A0A1B2I6H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

1197717:BED41 RS02270
gene id: 1197717:BED41_RS02270
uniprot id: A0A1B2I219
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1197717:BED41 RS07385
gene id: 1197717:BED41_RS07385
uniprot id: A0A1B2I4L1
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1197717:BED41 RS05915
gene id: 1197717:BED41_RS05915
uniprot id: A0A1B2I3X8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS15855
gene id: 1197717:BED41_RS15855
uniprot id: A0A1B2I927
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1197717:BED41 RS13520
gene id: 1197717:BED41_RS13520
uniprot id: A0A1B2I7S5
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.

1197717:BED41 RS04275
gene id: 1197717:BED41_RS04275
uniprot id: A0A1B2I9D1
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

1197717:BED41 RS06565
gene id: 1197717:BED41_RS06565
uniprot id: A0A1B2I472
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1197717:BED41 RS07275
gene id: 1197717:BED41_RS07275
uniprot id: A0A1B2I9H3
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1197717:BED41 RS15980
gene id: 1197717:BED41_RS15980
uniprot id: A0A1B2I955
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1197717:BED41 RS04980
gene id: 1197717:BED41_RS04980
uniprot id: A0A1B2I3D1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1197717:BED41 RS09945
gene id: 1197717:BED41_RS09945
uniprot id: A0A1B2I5V1
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1197717:BED41 RS15640
gene id: 1197717:BED41_RS15640
uniprot id: A0A1B2I8W5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1197717:BED41 RS00500
gene id: 1197717:BED41_RS00500
uniprot id: A0A1B2I1A7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1197717:BED41 RS15550
gene id: 1197717:BED41_RS15550
uniprot id: A0A1B2I8V7
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1197717:BED41 RS11260
gene id: 1197717:BED41_RS11260
uniprot id: A0A1B2I6J8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1197717:BED41 RS14675
gene id: 1197717:BED41_RS14675
uniprot id: A0A1B2I8E5
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1197717:BED41 RS15000
gene id: 1197717:BED41_RS15000
uniprot id: A0A1B2I8K7
names: Similarity
messages: Belongs to the trimethylamine methyltransferase family.

1197717:BED41 RS06165
gene id: 1197717:BED41_RS06165
uniprot id: A0A1B2I418
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1197717:BED41 RS08170
gene id: 1197717:BED41_RS08170
uniprot id: A0A1B2I4Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LPG synthase family.
messages: Membrane

1197717:BED41 RS03205
gene id: 1197717:BED41_RS03205
uniprot id: A0A1B2I2I0
names: Subcellular Location Annotation
messages: Cytoplasm

1197717:BED41 RS10290
gene id: 1197717:BED41_RS10290
uniprot id: A0A1B2I646
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

1197717:BED41 RS03805
gene id: 1197717:BED41_RS03805
uniprot id: A0A1B2I2W1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1197717:BED41 RS12190
gene id: 1197717:BED41_RS12190
uniprot id: A0A1B2I730
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1197717:BED41 RS06200
gene id: 1197717:BED41_RS06200
uniprot id: A0A1B2I420
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1197717:BED41 RS11810
gene id: 1197717:BED41_RS11810
uniprot id: A0A1B2I6U4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1197717:BED41 RS05850
gene id: 1197717:BED41_RS05850
uniprot id: A0A1B2I3W9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1197717:BED41 RS11890
gene id: 1197717:BED41_RS11890
uniprot id: A0A1B2I701
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

1197717:BED41 RS06820
gene id: 1197717:BED41_RS06820
uniprot id: A0A1B2I4B1
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS03770
gene id: 1197717:BED41_RS03770
uniprot id: A0A1B2I2V2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS07960
gene id: 1197717:BED41_RS07960
uniprot id: A0A1B2I4W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1197717:BED41 RS08885
gene id: 1197717:BED41_RS08885
uniprot id: A0A1B2I5C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1197717:BED41 RS08385
gene id: 1197717:BED41_RS08385
uniprot id: A0A1B2I567
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1197717:BED41 RS03555
gene id: 1197717:BED41_RS03555
uniprot id: A0A1B2I2S7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1197717:BED41 RS06185
gene id: 1197717:BED41_RS06185
uniprot id: A0A1B2I455
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1197717:BED41 RS15360
gene id: 1197717:BED41_RS15360
uniprot id: A0A1B2I8P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1197717:BED41 RS00825
gene id: 1197717:BED41_RS00825
uniprot id: A0A1B2I1E5
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS07065
gene id: 1197717:BED41_RS07065
uniprot id: A0A1B2I4K2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1197717:BED41 RS00760
gene id: 1197717:BED41_RS00760
uniprot id: A0A1B2I1C5
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS05630
gene id: 1197717:BED41_RS05630
uniprot id: A0A1B2I3R8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

1197717:BED41 RS07765
gene id: 1197717:BED41_RS07765
uniprot id: A0A1B2I4S4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1197717:BED41 RS04920
gene id: 1197717:BED41_RS04920
uniprot id: A0A1B2I3D6
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS01765
gene id: 1197717:BED41_RS01765
uniprot id: A0A1B2I1W2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1197717:BED41 RS09300
gene id: 1197717:BED41_RS09300
uniprot id: A0A1B2I5M2
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1197717:BED41 RS15465
gene id: 1197717:BED41_RS15465
uniprot id: A0A1B2I8W9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1197717:BED41 RS08710
gene id: 1197717:BED41_RS08710
uniprot id: A0A1B2I5B9
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS15125
gene id: 1197717:BED41_RS15125
uniprot id: A0A1B2I8Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

1197717:BED41 RS12365
gene id: 1197717:BED41_RS12365
uniprot id: A0A1B2I795
names: Similarity
messages: Belongs to the proline racemase family.

1197717:BED41 RS08780
gene id: 1197717:BED41_RS08780
uniprot id: A0A1B2I5D3
names: Similarity
messages: Belongs to the sigma-54 factor family.

1197717:BED41 RS01105
gene id: 1197717:BED41_RS01105
uniprot id: A0A1B2I1H0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1197717:BED41 RS10285
gene id: 1197717:BED41_RS10285
uniprot id: A0A1B2I634
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1197717:BED41 RS09015
gene id: 1197717:BED41_RS09015
uniprot id: A0A1B2I5E9
names: Subcellular Location Annotation
messages: Bacterial microcompartment

1197717:BED41 RS07780
gene id: 1197717:BED41_RS07780
uniprot id: A0A1B2I4T9
names: Similarity
messages: Belongs to the peptidase U62 family.

1197717:BED41 RS07925
gene id: 1197717:BED41_RS07925
uniprot id: A0A1B2I4W7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1197717:BED41 RS00420
gene id: 1197717:BED41_RS00420
uniprot id: A0A1B2I153
names: Similarity
messages: Belongs to the creatininase superfamily.

1197717:BED41 RS02805
gene id: 1197717:BED41_RS02805
uniprot id: A0A1B2I2C5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS00460
gene id: 1197717:BED41_RS00460
uniprot id: A0A1B2I169
names: Function
names: Similarity
messages: Belongs to the chloramphenicol acetyltransferase family.
messages: This enzyme is an effector of chloramphenicol resistance in bacteria.

1197717:BED41 RS07255
gene id: 1197717:BED41_RS07255
uniprot id: A0A1B2I4H6
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1197717:BED41 RS04190
gene id: 1197717:BED41_RS04190
uniprot id: A0A1B2I306
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

1197717:BED41 RS12095
gene id: 1197717:BED41_RS12095
uniprot id: A0A1B2I722
names: Similarity
messages: Belongs to the NifH/BchL/ChlL family.

1197717:BED41 RS08475
gene id: 1197717:BED41_RS08475
uniprot id: A0A1B2I557
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell membrane

1197717:BED41 RS02920
gene id: 1197717:BED41_RS02920
uniprot id: A0A1B2I2D4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1197717:BED41 RS07440
gene id: 1197717:BED41_RS07440
uniprot id: A0A1B2I4L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

1197717:BED41 RS10860
gene id: 1197717:BED41_RS10860
uniprot id: A0A1B2I6E9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS04205
gene id: 1197717:BED41_RS04205
uniprot id: A0A1B2I310
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1197717:BED41 RS02305
gene id: 1197717:BED41_RS02305
uniprot id: A0A1B2I240
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1197717:BED41 RS00410
gene id: 1197717:BED41_RS00410
uniprot id: A0A1B2I168
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

1197717:BED41 RS11830
gene id: 1197717:BED41_RS11830
uniprot id: A0A1B2I6V6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1197717:BED41 RS05920
gene id: 1197717:BED41_RS05920
uniprot id: A0A1B2I400
names: Similarity
messages: Belongs to the MreC family.

1197717:BED41 RS04365
gene id: 1197717:BED41_RS04365
uniprot id: A0A1B2I336
names: Similarity
messages: Belongs to the PRORSD1 family.

1197717:BED41 RS11325
gene id: 1197717:BED41_RS11325
uniprot id: A0A1B2I6K4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1197717:BED41 RS02710
gene id: 1197717:BED41_RS02710
uniprot id: A0A1B2I296
names: Similarity
messages: Belongs to the NadC/ModD family.

1197717:BED41 RS10675
gene id: 1197717:BED41_RS10675
uniprot id: A0A1B2I684
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS06110
gene id: 1197717:BED41_RS06110
uniprot id: A0A1B2I408
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1197717:BED41 RS14080
gene id: 1197717:BED41_RS14080
uniprot id: A0A1B2I818
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

1197717:BED41 RS02140
gene id: 1197717:BED41_RS02140
uniprot id: A0A1B2I1Z7
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS06125
gene id: 1197717:BED41_RS06125
uniprot id: A0A1B2I422
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS05045
gene id: 1197717:BED41_RS05045
uniprot id: A0A1B2I3F3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1197717:BED41 RS14705
gene id: 1197717:BED41_RS14705
uniprot id: A0A1B2I8F7
names: Similarity
messages: Belongs to the ComB family.

1197717:BED41 RS00165
gene id: 1197717:BED41_RS00165
uniprot id: A0A1B2I115
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1197717:BED41 RS15740
gene id: 1197717:BED41_RS15740
uniprot id: A0A1B2I910
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1197717:BED41 RS05755
gene id: 1197717:BED41_RS05755
uniprot id: A0A1B2I3S9
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1197717:BED41 RS02240
gene id: 1197717:BED41_RS02240
uniprot id: A0A1B2I225
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1197717:BED41 RS12575
gene id: 1197717:BED41_RS12575
uniprot id: A0A1B2I7B1
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1197717:BED41 RS09090
gene id: 1197717:BED41_RS09090
uniprot id: A0A1B2I5G3
names: Similarity
messages: Belongs to the DprA/Smf family.

1197717:BED41 RS12180
gene id: 1197717:BED41_RS12180
uniprot id: A0A1B2I718
names: Similarity
messages: Belongs to the IlvD/Edd family.

1197717:BED41 RS05140
gene id: 1197717:BED41_RS05140
uniprot id: A0A1B2I3J9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1197717:BED41 RS14750
gene id: 1197717:BED41_RS14750
uniprot id: A0A1B2I8E6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1197717:BED41 RS00570
gene id: 1197717:BED41_RS00570
uniprot id: A0A1B2I183
names: Similarity
messages: Belongs to the PrpF family.

1197717:BED41 RS06140
gene id: 1197717:BED41_RS06140
uniprot id: A0A1B2I401
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS01560
gene id: 1197717:BED41_RS01560
uniprot id: A0A1B2I1N7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1197717:BED41 RS14850
gene id: 1197717:BED41_RS14850
uniprot id: A0A1B2I8G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1197717:BED41 RS08185
gene id: 1197717:BED41_RS08185
uniprot id: A0A1B2I508
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1197717:BED41 RS15880
gene id: 1197717:BED41_RS15880
uniprot id: A0A1B2I8Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1197717:BED41 RS07565
gene id: 1197717:BED41_RS07565
uniprot id: A0A1B2I4S2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1197717:BED41 RS15905
gene id: 1197717:BED41_RS15905
uniprot id: A0A1B2I937
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1197717:BED41 RS05450
gene id: 1197717:BED41_RS05450
uniprot id: A0A1B2I3P6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

1197717:BED41 RS14010
gene id: 1197717:BED41_RS14010
uniprot id: A0A1B2I820
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1197717:BED41 RS08695
gene id: 1197717:BED41_RS08695
uniprot id: A0A1B2I583
names: Similarity
messages: Belongs to the YciI family.

1197717:BED41 RS16760
gene id: 1197717:BED41_RS16760
uniprot id: A0A1B2I3V9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

1197717:BED41 RS04770
gene id: 1197717:BED41_RS04770
uniprot id: A0A1B2I3D0
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1197717:BED41 RS13930
gene id: 1197717:BED41_RS13930
uniprot id: A0A1B2I807
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS06095
gene id: 1197717:BED41_RS06095
uniprot id: A0A1B2I430
names: Function
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

1197717:BED41 RS07990
gene id: 1197717:BED41_RS07990
uniprot id: A0A1B2I4Z7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1197717:BED41 RS06145
gene id: 1197717:BED41_RS06145
uniprot id: A0A1B2I403
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1197717:BED41 RS16015
gene id: 1197717:BED41_RS16015
uniprot id: A0A1B2I902
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1197717:BED41 RS07685
gene id: 1197717:BED41_RS07685
uniprot id: A0A1B2I4R1
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1197717:BED41 RS06930
gene id: 1197717:BED41_RS06930
uniprot id: A0A1B2I4C4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1197717:BED41 RS08585
gene id: 1197717:BED41_RS08585
uniprot id: A0A1B2I596
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1197717:BED41 RS01885
gene id: 1197717:BED41_RS01885
uniprot id: A0A1B2I1V7
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1197717:BED41 RS15570
gene id: 1197717:BED41_RS15570
uniprot id: A0A1B2I8S2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1197717:BED41 RS07245
gene id: 1197717:BED41_RS07245
uniprot id: A0A1B2I4J7
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1197717:BED41 RS01965
gene id: 1197717:BED41_RS01965
uniprot id: A0A1B2I1X8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS03510
gene id: 1197717:BED41_RS03510
uniprot id: A0A1B2I2N8
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

1197717:BED41 RS13375
gene id: 1197717:BED41_RS13375
uniprot id: A0A1B2I7P7
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1197717:BED41 RS09905
gene id: 1197717:BED41_RS09905
uniprot id: A0A1B2I5V6
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1197717:BED41 RS15555
gene id: 1197717:BED41_RS15555
uniprot id: A0A1B2I8V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1197717:BED41 RS10355
gene id: 1197717:BED41_RS10355
uniprot id: A0A1B2I638
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1197717:BED41 RS12640
gene id: 1197717:BED41_RS12640
uniprot id: A0A1B2I7E5
names: Similarity
messages: Belongs to the GSP E family.

1197717:BED41 RS07310
gene id: 1197717:BED41_RS07310
uniprot id: A0A1B2I4I6
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS10815
gene id: 1197717:BED41_RS10815
uniprot id: A0A1B2I6B1
names: Similarity
messages: Belongs to the Fur family.

1197717:BED41 RS12255
gene id: 1197717:BED41_RS12255
uniprot id: A0A1B2I742
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1197717:BED41 RS05430
gene id: 1197717:BED41_RS05430
uniprot id: A0A1B2I3Q9
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1197717:BED41 RS00715
gene id: 1197717:BED41_RS00715
uniprot id: A0A1B2I1B9
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS15130
gene id: 1197717:BED41_RS15130
uniprot id: A0A1B2I8N6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1197717:BED41 RS07085
gene id: 1197717:BED41_RS07085
uniprot id: A0A1B2I4J5
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS04395
gene id: 1197717:BED41_RS04395
uniprot id: A0A1B2I339
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1197717:BED41 RS13610
gene id: 1197717:BED41_RS13610
uniprot id: A0A1B2I7T7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1197717:BED41 RS11395
gene id: 1197717:BED41_RS11395
uniprot id: A0A1B2I6N4
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.

1197717:BED41 RS14690
gene id: 1197717:BED41_RS14690
uniprot id: A0A1B2I8E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1197717:BED41 RS09320
gene id: 1197717:BED41_RS09320
uniprot id: A0A1B2I5J5
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1197717:BED41 RS06180
gene id: 1197717:BED41_RS06180
uniprot id: A0A1B2I431
names: Similarity
messages: Belongs to the fabD family.

1197717:BED41 RS09165
gene id: 1197717:BED41_RS09165
uniprot id: A0A1B2I5J1
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1197717:BED41 RS07500
gene id: 1197717:BED41_RS07500
uniprot id: A0A1B2I4N0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1197717:BED41 RS07980
gene id: 1197717:BED41_RS07980
uniprot id: A0A1B2I4X6
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS06340
gene id: 1197717:BED41_RS06340
uniprot id: A0A1B2I459
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1197717:BED41 RS12325
gene id: 1197717:BED41_RS12325
uniprot id: A0A1B2I749
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1197717:BED41 RS01700
gene id: 1197717:BED41_RS01700
uniprot id: A0A1B2I1R3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1197717:BED41 RS08005
gene id: 1197717:BED41_RS08005
uniprot id: A0A1B2I4Y6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS11575
gene id: 1197717:BED41_RS11575
uniprot id: A0A1B2I6Q8
names: Similarity
messages: Belongs to the FGGY kinase family.

1197717:BED41 RS00150
gene id: 1197717:BED41_RS00150
uniprot id: A0A1B2I104
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1197717:BED41 RS02000
gene id: 1197717:BED41_RS02000
uniprot id: A0A1B2I1Y7
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS05165
gene id: 1197717:BED41_RS05165
uniprot id: A0A1B2I3L0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1197717:BED41 RS12570
gene id: 1197717:BED41_RS12570
uniprot id: A0A1B2I797
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

1197717:BED41 RS05100
gene id: 1197717:BED41_RS05100
uniprot id: A0A1B2I3H1
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1197717:BED41 RS12940
gene id: 1197717:BED41_RS12940
uniprot id: A0A1B2I7H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

1197717:BED41 RS01770
gene id: 1197717:BED41_RS01770
uniprot id: A0A1B2I1S5
names: Similarity
messages: Belongs to the NadC/ModD family.

1197717:BED41 RS00230
gene id: 1197717:BED41_RS00230
uniprot id: A0A1B2I130
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1197717:BED41 RS02720
gene id: 1197717:BED41_RS02720
uniprot id: A0A1B2I2B2
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1197717:BED41 RS05060
gene id: 1197717:BED41_RS05060
uniprot id: A0A1B2I3E8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1197717:BED41 RS08905
gene id: 1197717:BED41_RS08905
uniprot id: A0A1B2I5C7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1197717:BED41 RS15990
gene id: 1197717:BED41_RS15990
uniprot id: A0A1B2I914
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1197717:BED41 RS11550
gene id: 1197717:BED41_RS11550
uniprot id: A0A1B2I6R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1197717:BED41 RS05440
gene id: 1197717:BED41_RS05440
uniprot id: A0A1B2I3N7
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1197717:BED41 RS13175
gene id: 1197717:BED41_RS13175
uniprot id: A0A1B2I7K5
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

1197717:BED41 RS02960
gene id: 1197717:BED41_RS02960
uniprot id: A0A1B2I2H0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1197717:BED41 RS03590
gene id: 1197717:BED41_RS03590
uniprot id: A0A1B2I2S2
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS09805
gene id: 1197717:BED41_RS09805
uniprot id: A0A1B2I5T3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1197717:BED41 RS04125
gene id: 1197717:BED41_RS04125
uniprot id: A0A1B2I302
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

1197717:BED41 RS06075
gene id: 1197717:BED41_RS06075
uniprot id: A0A1B2I433
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1197717:BED41 RS05980
gene id: 1197717:BED41_RS05980
uniprot id: A0A1B2I3Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1197717:BED41 RS10085
gene id: 1197717:BED41_RS10085
uniprot id: A0A1B2I5X3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1197717:BED41 RS15425
gene id: 1197717:BED41_RS15425
uniprot id: A0A1B2I8R9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1197717:BED41 RS16735
gene id: 1197717:BED41_RS16735
uniprot id: A0A1B2I9A6
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1197717:BED41 RS00680
gene id: 1197717:BED41_RS00680
uniprot id: A0A1B2I191
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1197717:BED41 RS03650
gene id: 1197717:BED41_RS03650
uniprot id: A0A1B2I2T1
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1197717:BED41 RS14375
gene id: 1197717:BED41_RS14375
uniprot id: A0A1B2I874
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1197717:BED41 RS09445
gene id: 1197717:BED41_RS09445
uniprot id: A0A1B2I5N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1197717:BED41 RS04640
gene id: 1197717:BED41_RS04640
uniprot id: A0A1B2I383
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.

1197717:BED41 RS04115
gene id: 1197717:BED41_RS04115
uniprot id: A0A1B2I2Z5
names: Similarity
messages: Belongs to the EutP/PduV family.

1197717:BED41 RS09110
gene id: 1197717:BED41_RS09110
uniprot id: A0A1B2I5I1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

1197717:BED41 RS06960
gene id: 1197717:BED41_RS06960
uniprot id: A0A1B2I4E1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1197717:BED41 RS06010
gene id: 1197717:BED41_RS06010
uniprot id: A0A1B2I9H1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1197717:BED41 RS11625
gene id: 1197717:BED41_RS11625
uniprot id: A0A1B2I6U6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS02780
gene id: 1197717:BED41_RS02780
uniprot id: A0A1B2I2B1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1197717:BED41 RS01315
gene id: 1197717:BED41_RS01315
uniprot id: A0A1B2I1L4
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS06700
gene id: 1197717:BED41_RS06700
uniprot id: A0A1B2I4A0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1197717:BED41 RS06400
gene id: 1197717:BED41_RS06400
uniprot id: A0A1B2I9C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1197717:BED41 RS07970
gene id: 1197717:BED41_RS07970
uniprot id: A0A1B2I4W3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1197717:BED41 RS12765
gene id: 1197717:BED41_RS12765
uniprot id: A0A1B2I7D1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1197717:BED41 RS07760
gene id: 1197717:BED41_RS07760
uniprot id: A0A1B2I4T7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1197717:BED41 RS05650
gene id: 1197717:BED41_RS05650
uniprot id: A0A1B2I3V2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1197717:BED41 RS03865
gene id: 1197717:BED41_RS03865
uniprot id: A0A1B2I2V7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1197717:BED41 RS07530
gene id: 1197717:BED41_RS07530
uniprot id: A0A1B2I4S3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1197717:BED41 RS04140
gene id: 1197717:BED41_RS04140
uniprot id: A0A1B2I307
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

1197717:BED41 RS04155
gene id: 1197717:BED41_RS04155
uniprot id: A0A1B2I2Z4
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

1197717:BED41 RS15715
gene id: 1197717:BED41_RS15715
uniprot id: A0A1B2I8W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1197717:BED41 RS09510
gene id: 1197717:BED41_RS09510
uniprot id: A0A1B2I5P8
names: Similarity
messages: Belongs to the FBPase class 2 family.

1197717:BED41 RS10655
gene id: 1197717:BED41_RS10655
uniprot id: A0A1B2I6B9
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1197717:BED41 RS05155
gene id: 1197717:BED41_RS05155
uniprot id: A0A1B2I3I2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1197717:BED41 RS03725
gene id: 1197717:BED41_RS03725
uniprot id: A0A1B2I2S8
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS08190
gene id: 1197717:BED41_RS08190
uniprot id: A0A1B2I511
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1197717:BED41 RS12455
gene id: 1197717:BED41_RS12455
uniprot id: A0A1B2I786
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1197717:BED41 RS08315
gene id: 1197717:BED41_RS08315
uniprot id: A0A1B2I532
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS09725
gene id: 1197717:BED41_RS09725
uniprot id: A0A1B2I5R8
names: Similarity
messages: Belongs to the GSP E family.

1197717:BED41 RS12715
gene id: 1197717:BED41_RS12715
uniprot id: A0A1B2I7B9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1197717:BED41 RS04775
gene id: 1197717:BED41_RS04775
uniprot id: A0A1B2I3A6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

1197717:BED41 RS07230
gene id: 1197717:BED41_RS07230
uniprot id: A0A1B2I4M4
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1197717:BED41 RS14385
gene id: 1197717:BED41_RS14385
uniprot id: A0A1B2I892
names: Similarity
messages: Belongs to the peptidase S8 family.

1197717:BED41 RS13260
gene id: 1197717:BED41_RS13260
uniprot id: A0A1B2I7N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1197717:BED41 RS10900
gene id: 1197717:BED41_RS10900
uniprot id: A0A1B2I6E3
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1197717:BED41 RS04655
gene id: 1197717:BED41_RS04655
uniprot id: A0A1B2I394
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1197717:BED41 RS12675
gene id: 1197717:BED41_RS12675
uniprot id: A0A1B2I7C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

1197717:BED41 RS00005
gene id: 1197717:BED41_RS00005
uniprot id: A0A1B2I0V1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1197717:BED41 RS14805
gene id: 1197717:BED41_RS14805
uniprot id: A0A1B2I8F0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm

1197717:BED41 RS07665
gene id: 1197717:BED41_RS07665
uniprot id: A0A1B2I4R0
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1197717:BED41 RS10110
gene id: 1197717:BED41_RS10110
uniprot id: A0A1B2I608
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1197717:BED41 RS14175
gene id: 1197717:BED41_RS14175
uniprot id: A0A1B2I852
names: Similarity
messages: Belongs to the Skp family.

1197717:BED41 RS03920
gene id: 1197717:BED41_RS03920
uniprot id: A0A1B2I2W7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1197717:BED41 RS07930
gene id: 1197717:BED41_RS07930
uniprot id: A0A1B2I4Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1197717:BED41 RS02035
gene id: 1197717:BED41_RS02035
uniprot id: A0A1B2I206
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1197717:BED41 RS06855
gene id: 1197717:BED41_RS06855
uniprot id: A0A1B2I4C8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1197717:BED41 RS04635
gene id: 1197717:BED41_RS04635
uniprot id: A0A1B2I3B5
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

1197717:BED41 RS00365
gene id: 1197717:BED41_RS00365
uniprot id: A0A1B2I147
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS05555
gene id: 1197717:BED41_RS05555
uniprot id: A0A1B2I3P0
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1197717:BED41 RS13870
gene id: 1197717:BED41_RS13870
uniprot id: A0A1B2I7X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1197717:BED41 RS06540
gene id: 1197717:BED41_RS06540
uniprot id: A0A1B2I480
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

1197717:BED41 RS07460
gene id: 1197717:BED41_RS07460
uniprot id: A0A1B2I4L8
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

1197717:BED41 RS08180
gene id: 1197717:BED41_RS08180
uniprot id: A0A1B2I539
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1197717:BED41 RS07045
gene id: 1197717:BED41_RS07045
uniprot id: A0A1B2I4G2
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1197717:BED41 RS10190
gene id: 1197717:BED41_RS10190
uniprot id: A0A1B2I5Z6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1197717:BED41 RS00805
gene id: 1197717:BED41_RS00805
uniprot id: A0A1B2I1C4
names: Similarity
messages: Belongs to the glutamine synthetase family.

1197717:BED41 RS15280
gene id: 1197717:BED41_RS15280
uniprot id: A0A1B2I8P7
names: Similarity
messages: Belongs to the YoeB family.

1197717:BED41 RS03620
gene id: 1197717:BED41_RS03620
uniprot id: A0A1B2I2Q8
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS09085
gene id: 1197717:BED41_RS09085
uniprot id: A0A1B2I5F5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1197717:BED41 RS03240
gene id: 1197717:BED41_RS03240
uniprot id: A0A1B2I2I5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1197717:BED41 RS04815
gene id: 1197717:BED41_RS04815
uniprot id: A0A1B2I3C7
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS09870
gene id: 1197717:BED41_RS09870
uniprot id: A0A1B2I5U8
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS07285
gene id: 1197717:BED41_RS07285
uniprot id: A0A1B2I4N3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1197717:BED41 RS10715
gene id: 1197717:BED41_RS10715
uniprot id: A0A1B2I690
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

1197717:BED41 RS12990
gene id: 1197717:BED41_RS12990
uniprot id: A0A1B2I7I1
names: Similarity
messages: Belongs to the RutC family.

1197717:BED41 RS02135
gene id: 1197717:BED41_RS02135
uniprot id: A0A1B2I1Z5
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1197717:BED41 RS11070
gene id: 1197717:BED41_RS11070
uniprot id: A0A1B2I6H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1197717:BED41 RS01695
gene id: 1197717:BED41_RS01695
uniprot id: A0A1B2I1R5
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS02735
gene id: 1197717:BED41_RS02735
uniprot id: A0A1B2I299
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1197717:BED41 RS06605
gene id: 1197717:BED41_RS06605
uniprot id: A0A1B2I4B5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1197717:BED41 RS09835
gene id: 1197717:BED41_RS09835
uniprot id: A0A1B2I5T5
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1197717:BED41 RS11895
gene id: 1197717:BED41_RS11895
uniprot id: A0A1B2I6W0
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

1197717:BED41 RS07690
gene id: 1197717:BED41_RS07690
uniprot id: A0A1B2I4S9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1197717:BED41 RS08560
gene id: 1197717:BED41_RS08560
uniprot id: A0A1B2I569
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1197717:BED41 RS16000
gene id: 1197717:BED41_RS16000
uniprot id: A0A1B2I942
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1197717:BED41 RS09380
gene id: 1197717:BED41_RS09380
uniprot id: A0A1B2I5N1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1197717:BED41 RS07625
gene id: 1197717:BED41_RS07625
uniprot id: A0A1B2I4T2
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

1197717:BED41 RS09430
gene id: 1197717:BED41_RS09430
uniprot id: A0A1B2I5L3
names: Similarity
messages: Belongs to the asparagine synthetase family.

1197717:BED41 RS05220
gene id: 1197717:BED41_RS05220
uniprot id: A0A1B2I3N0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1197717:BED41 RS07020
gene id: 1197717:BED41_RS07020
uniprot id: A0A1B2I4F6
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1197717:BED41 RS00700
gene id: 1197717:BED41_RS00700
uniprot id: A0A1B2I1A4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1197717:BED41 RS06515
gene id: 1197717:BED41_RS06515
uniprot id: A0A1B2I467
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1197717:BED41 RS11335
gene id: 1197717:BED41_RS11335
uniprot id: A0A1B2I6N9
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

1197717:BED41 RS12355
gene id: 1197717:BED41_RS12355
uniprot id: A0A1B2I760
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1197717:BED41 RS05150
gene id: 1197717:BED41_RS05150
uniprot id: A0A1B2I3I5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1197717:BED41 RS09590
gene id: 1197717:BED41_RS09590
uniprot id: A0A1B2I5Q2
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1197717:BED41 RS11570
gene id: 1197717:BED41_RS11570
uniprot id: A0A1B2I6Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1197717:BED41 RS00305
gene id: 1197717:BED41_RS00305
uniprot id: A0A1B2I133
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1197717:BED41 RS03870
gene id: 1197717:BED41_RS03870
uniprot id: A0A1B2I2V8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1197717:BED41 RS10510
gene id: 1197717:BED41_RS10510
uniprot id: A0A1B2I654
names: Similarity
messages: Belongs to the peptidase S14 family.

1197717:BED41 RS02660
gene id: 1197717:BED41_RS02660
uniprot id: A0A1B2I286
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1197717:BED41 RS13715
gene id: 1197717:BED41_RS13715
uniprot id: A0A1B2I7W7
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1197717:BED41 RS10065
gene id: 1197717:BED41_RS10065
uniprot id: A0A1B2I5Y9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

1197717:BED41 RS05320
gene id: 1197717:BED41_RS05320
uniprot id: A0A1B2I3P1
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

1197717:BED41 RS15645
gene id: 1197717:BED41_RS15645
uniprot id: A0A1B2I8Z6
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS03790
gene id: 1197717:BED41_RS03790
uniprot id: A0A1B2I2T8
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1197717:BED41 RS02095
gene id: 1197717:BED41_RS02095
uniprot id: A0A1B2I1Y9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1197717:BED41 RS09315
gene id: 1197717:BED41_RS09315
uniprot id: A0A1B2I5K2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS11480
gene id: 1197717:BED41_RS11480
uniprot id: A0A1B2I6N3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS09895
gene id: 1197717:BED41_RS09895
uniprot id: A0A1B2I5W0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS10665
gene id: 1197717:BED41_RS10665
uniprot id: A0A1B2I686
names: Similarity
messages: Belongs to the UPF0237 family.

1197717:BED41 RS06600
gene id: 1197717:BED41_RS06600
uniprot id: A0A1B2I491
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1197717:BED41 RS00355
gene id: 1197717:BED41_RS00355
uniprot id: A0A1B2I146
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1197717:BED41 RS00685
gene id: 1197717:BED41_RS00685
uniprot id: A0A1B2I195
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1197717:BED41 RS10035
gene id: 1197717:BED41_RS10035
uniprot id: A0A1B2I5X6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1197717:BED41 RS03815
gene id: 1197717:BED41_RS03815
uniprot id: A0A1B2I2U5
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS14300
gene id: 1197717:BED41_RS14300
uniprot id: A0A1B2I8A0
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS06915
gene id: 1197717:BED41_RS06915
uniprot id: A0A1B2I4D6
names: Subcellular Location Annotation
messages: Cytoplasm

1197717:BED41 RS14245
gene id: 1197717:BED41_RS14245
uniprot id: A0A1B2I895
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1197717:BED41 RS06765
gene id: 1197717:BED41_RS06765
uniprot id: A0A1B2I4C7
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1197717:BED41 RS15070
gene id: 1197717:BED41_RS15070
uniprot id: A0A1B2I8P3
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1197717:BED41 RS08070
gene id: 1197717:BED41_RS08070
uniprot id: A0A1B2I4Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1197717:BED41 RS11740
gene id: 1197717:BED41_RS11740
uniprot id: A0A1B2I6T9
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

1197717:BED41 RS06120
gene id: 1197717:BED41_RS06120
uniprot id: A0A1B2I3Z6
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS00330
gene id: 1197717:BED41_RS00330
uniprot id: A0A1B2I145
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS05900
gene id: 1197717:BED41_RS05900
uniprot id: A0A1B2I404
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1197717:BED41 RS05250
gene id: 1197717:BED41_RS05250
uniprot id: A0A1B2I3K4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS00800
gene id: 1197717:BED41_RS00800
uniprot id: A0A1B2I1F6
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1197717:BED41 RS11175
gene id: 1197717:BED41_RS11175
uniprot id: A0A1B2I6H7
names: Similarity
messages: Belongs to the CdaR family.

1197717:BED41 RS09025
gene id: 1197717:BED41_RS09025
uniprot id: A0A1B2I5E5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS03380
gene id: 1197717:BED41_RS03380
uniprot id: A0A1B2I2M8
names: Subcellular Location Annotation
messages: Virion

1197717:BED41 RS08920
gene id: 1197717:BED41_RS08920
uniprot id: A0A1B2I5D5
names: Similarity
messages: Belongs to the EutP/PduV family.

1197717:BED41 RS04535
gene id: 1197717:BED41_RS04535
uniprot id: A0A1B2I377
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1197717:BED41 RS10735
gene id: 1197717:BED41_RS10735
uniprot id: A0A1B2I698
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1197717:BED41 RS03125
gene id: 1197717:BED41_RS03125
uniprot id: A0A1B2I2J7
names: Subcellular Location Annotation
messages: Cytoplasm

1197717:BED41 RS11975
gene id: 1197717:BED41_RS11975
uniprot id: A0A1B2I6X7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1197717:BED41 RS07660
gene id: 1197717:BED41_RS07660
uniprot id: A0A1B2I4R7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1197717:BED41 RS08040
gene id: 1197717:BED41_RS08040
uniprot id: A0A1B2I509
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1197717:BED41 RS05115
gene id: 1197717:BED41_RS05115
uniprot id: A0A1B2I3K3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1197717:BED41 RS05435
gene id: 1197717:BED41_RS05435
uniprot id: A0A1B2I3S3
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1197717:BED41 RS02590
gene id: 1197717:BED41_RS02590
uniprot id: A0A1B2I276
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1197717:BED41 RS03850
gene id: 1197717:BED41_RS03850
uniprot id: A0A1B2I2V6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS11645
gene id: 1197717:BED41_RS11645
uniprot id: A0A1B2I6R3
names: Caution
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS05055
gene id: 1197717:BED41_RS05055
uniprot id: A0A1B2I3G1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1197717:BED41 RS15690
gene id: 1197717:BED41_RS15690
uniprot id: A0A1B2I900
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1197717:BED41 RS00040
gene id: 1197717:BED41_RS00040
uniprot id: A0A1B2I0X6
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS13065
gene id: 1197717:BED41_RS13065
uniprot id: A0A1B2I7J1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1197717:BED41 RS02650
gene id: 1197717:BED41_RS02650
uniprot id: A0A1B2I295
names: Similarity
messages: Belongs to the UPF0178 family.

1197717:BED41 RS13395
gene id: 1197717:BED41_RS13395
uniprot id: A0A1B2I7Q6
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1197717:BED41 RS03630
gene id: 1197717:BED41_RS03630
uniprot id: A0A1B2I2R4
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

1197717:BED41 RS03190
gene id: 1197717:BED41_RS03190
uniprot id: A0A1B2I2H8
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1197717:BED41 RS11915
gene id: 1197717:BED41_RS11915
uniprot id: A0A1B2I6X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1197717:BED41 RS05275
gene id: 1197717:BED41_RS05275
uniprot id: A0A1B2I3K7
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1197717:BED41 RS03110
gene id: 1197717:BED41_RS03110
uniprot id: A0A1B2I2G8
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1197717:BED41 RS05085
gene id: 1197717:BED41_RS05085
uniprot id: A0A1B2I3H2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1197717:BED41 RS12775
gene id: 1197717:BED41_RS12775
uniprot id: A0A1B2I7E6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1197717:BED41 RS00755
gene id: 1197717:BED41_RS00755
uniprot id: A0A1B2I1B5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS09515
gene id: 1197717:BED41_RS09515
uniprot id: A0A1B2I5Q4
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1197717:BED41 RS02775
gene id: 1197717:BED41_RS02775
uniprot id: A0A1B2I2D8
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS05185
gene id: 1197717:BED41_RS05185
uniprot id: A0A1B2I3J1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

1197717:BED41 RS12875
gene id: 1197717:BED41_RS12875
uniprot id: A0A1B2I7G7
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1197717:BED41 RS06055
gene id: 1197717:BED41_RS06055
uniprot id: A0A1B2I3X9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1197717:BED41 RS11100
gene id: 1197717:BED41_RS11100
uniprot id: A0A1B2I6G5
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS11990
gene id: 1197717:BED41_RS11990
uniprot id: A0A1B2I6Y9
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1197717:BED41 RS02470
gene id: 1197717:BED41_RS02470
uniprot id: A0A1B2I269
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1197717:BED41 RS15630
gene id: 1197717:BED41_RS15630
uniprot id: A0A1B2I8T2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1197717:BED41 RS09620
gene id: 1197717:BED41_RS09620
uniprot id: A0A1B2I5Q8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1197717:BED41 RS03955
gene id: 1197717:BED41_RS03955
uniprot id: A0A1B2I2X3
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS15220
gene id: 1197717:BED41_RS15220
uniprot id: A0A1B2I8N9
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1197717:BED41 RS14560
gene id: 1197717:BED41_RS14560
uniprot id: A0A1B2I8C1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1197717:BED41 RS13580
gene id: 1197717:BED41_RS13580
uniprot id: A0A1B2I7T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1197717:BED41 RS07650
gene id: 1197717:BED41_RS07650
uniprot id: A0A1B2I4Q9
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1197717:BED41 RS04600
gene id: 1197717:BED41_RS04600
uniprot id: A0A1B2I382
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

1197717:BED41 RS13790
gene id: 1197717:BED41_RS13790
uniprot id: A0A1B2I7Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1197717:BED41 RS14825
gene id: 1197717:BED41_RS14825
uniprot id: A0A1B2I8F1
names: Similarity
messages: Belongs to the proline racemase family.

1197717:BED41 RS13005
gene id: 1197717:BED41_RS13005
uniprot id: A0A1B2I7L4
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1197717:BED41 RS15045
gene id: 1197717:BED41_RS15045
uniprot id: A0A1B2I8J5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1197717:BED41 RS12695
gene id: 1197717:BED41_RS12695
uniprot id: A0A1B2I7B3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1197717:BED41 RS06560
gene id: 1197717:BED41_RS06560
uniprot id: A0A1B2I493
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1197717:BED41 RS09540
gene id: 1197717:BED41_RS09540
uniprot id: A0A1B2I5Q0
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1197717:BED41 RS10810
gene id: 1197717:BED41_RS10810
uniprot id: A0A1B2I6E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1197717:BED41 RS10825
gene id: 1197717:BED41_RS10825
uniprot id: A0A1B2I6C9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS03145
gene id: 1197717:BED41_RS03145
uniprot id: A0A1B2I2H2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1197717:BED41 RS12335
gene id: 1197717:BED41_RS12335
uniprot id: A0A1B2I748
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1197717:BED41 RS07520
gene id: 1197717:BED41_RS07520
uniprot id: A0A1B2I4N1
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS06755
gene id: 1197717:BED41_RS06755
uniprot id: A0A1B2I4B0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1197717:BED41 RS02385
gene id: 1197717:BED41_RS02385
uniprot id: A0A1B2I242
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1197717:BED41 RS02995
gene id: 1197717:BED41_RS02995
uniprot id: A0A1B2I2E9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1197717:BED41 RS01085
gene id: 1197717:BED41_RS01085
uniprot id: A0A1B2I1J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1197717:BED41 RS15410
gene id: 1197717:BED41_RS15410
uniprot id: A0A1B2I8V5
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1197717:BED41 RS07775
gene id: 1197717:BED41_RS07775
uniprot id: A0A1B2I4W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

1197717:BED41 RS12155
gene id: 1197717:BED41_RS12155
uniprot id: A0A1B2I714
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

1197717:BED41 RS02750
gene id: 1197717:BED41_RS02750
uniprot id: A0A1B2I2B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1197717:BED41 RS00890
gene id: 1197717:BED41_RS00890
uniprot id: A0A1B2I1C9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1197717:BED41 RS11845
gene id: 1197717:BED41_RS11845
uniprot id: A0A1B2I6V1
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.

1197717:BED41 RS15870
gene id: 1197717:BED41_RS15870
uniprot id: A0A1B2I8Y0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1197717:BED41 RS09485
gene id: 1197717:BED41_RS09485
uniprot id: A0A1B2I5M4
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

1197717:BED41 RS05540
gene id: 1197717:BED41_RS05540
uniprot id: A0A1B2I3N8
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1197717:BED41 RS05280
gene id: 1197717:BED41_RS05280
uniprot id: A0A1B2I3J6
names: Similarity
messages: Belongs to the CarB family.

1197717:BED41 RS05095
gene id: 1197717:BED41_RS05095
uniprot id: A0A1B2I3G2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1197717:BED41 RS10260
gene id: 1197717:BED41_RS10260
uniprot id: A0A1B2I606
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1197717:BED41 RS02060
gene id: 1197717:BED41_RS02060
uniprot id: A0A1B2I1Z6
names: Subcellular Location Annotation
messages: Cytoplasm

1197717:BED41 RS04670
gene id: 1197717:BED41_RS04670
uniprot id: A0A1B2I3D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

1197717:BED41 RS08630
gene id: 1197717:BED41_RS08630
uniprot id: A0A1B2I591
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1197717:BED41 RS01795
gene id: 1197717:BED41_RS01795
uniprot id: A0A1B2I1V0
names: Similarity
messages: Belongs to the TPP enzyme family.

1197717:BED41 RS10870
gene id: 1197717:BED41_RS10870
uniprot id: A0A1B2I6C1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.

1197717:BED41 RS00315
gene id: 1197717:BED41_RS00315
uniprot id: A0A1B2I170
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1197717:BED41 RS00435
gene id: 1197717:BED41_RS00435
uniprot id: A0A1B2I164
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1197717:BED41 RS03960
gene id: 1197717:BED41_RS03960
uniprot id: A0A1B2I2Z8
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS00345
gene id: 1197717:BED41_RS00345
uniprot id: A0A1B2I152
names: Subcellular Location Annotation
messages: Cytoplasm

1197717:BED41 RS09285
gene id: 1197717:BED41_RS09285
uniprot id: A0A1B2I5K4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1197717:BED41 RS04780
gene id: 1197717:BED41_RS04780
uniprot id: A0A1B2I3B6
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1197717:BED41 RS02130
gene id: 1197717:BED41_RS02130
uniprot id: A0A1B2I204
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1197717:BED41 RS12770
gene id: 1197717:BED41_RS12770
uniprot id: A0A1B2I7E7
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1197717:BED41 RS02970
gene id: 1197717:BED41_RS02970
uniprot id: A0A1B2I2E1
names: Similarity
messages: Belongs to the PrpF family.

1197717:BED41 RS12530
gene id: 1197717:BED41_RS12530
uniprot id: A0A1B2I783
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

1197717:BED41 RS08165
gene id: 1197717:BED41_RS08165
uniprot id: A0A1B2I507
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS11880
gene id: 1197717:BED41_RS11880
uniprot id: A0A1B2I6W8
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

1197717:BED41 RS03135
gene id: 1197717:BED41_RS03135
uniprot id: A0A1B2I2H1
names: Subcellular Location Annotation
messages: Cytoplasm

1197717:BED41 RS05000
gene id: 1197717:BED41_RS05000
uniprot id: A0A1B2I3F4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS07025
gene id: 1197717:BED41_RS07025
uniprot id: A0A1B2I4G9
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1197717:BED41 RS04590
gene id: 1197717:BED41_RS04590
uniprot id: A0A1B2I371
names: Similarity
messages: Belongs to the leucine-binding protein family.

1197717:BED41 RS07860
gene id: 1197717:BED41_RS07860
uniprot id: A0A1B2I4V7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS03915
gene id: 1197717:BED41_RS03915
uniprot id: A0A1B2I2W6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS00560
gene id: 1197717:BED41_RS00560
uniprot id: A0A1B2I175
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

1197717:BED41 RS01970
gene id: 1197717:BED41_RS01970
uniprot id: A0A1B2I1Z9
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS03595
gene id: 1197717:BED41_RS03595
uniprot id: A0A1B2I2Q7
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS09325
gene id: 1197717:BED41_RS09325
uniprot id: A0A1B2I5K6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1197717:BED41 RS09145
gene id: 1197717:BED41_RS09145
uniprot id: A0A1B2I5G9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS01535
gene id: 1197717:BED41_RS01535
uniprot id: A0A1B2I1N1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1197717:BED41 RS03740
gene id: 1197717:BED41_RS03740
uniprot id: A0A1B2I2V3
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ser-Ser-Gly.
messages: Cytoplasm

1197717:BED41 RS00525
gene id: 1197717:BED41_RS00525
uniprot id: A0A1B2I181
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS05840
gene id: 1197717:BED41_RS05840
uniprot id: A0A1B2I3V1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

1197717:BED41 RS10990
gene id: 1197717:BED41_RS10990
uniprot id: A0A1B2I6E6
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS10895
gene id: 1197717:BED41_RS10895
uniprot id: A0A1B2I6F7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1197717:BED41 RS07915
gene id: 1197717:BED41_RS07915
uniprot id: A0A1B2I4W5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1197717:BED41 RS15275
gene id: 1197717:BED41_RS15275
uniprot id: A0A1B2I9T2
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1197717:BED41 RS00530
gene id: 1197717:BED41_RS00530
uniprot id: A0A1B2I171
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1197717:BED41 RS00910
gene id: 1197717:BED41_RS00910
uniprot id: A0A1B2I1D7
names: Similarity
messages: Belongs to the peptidase S8 family.

1197717:BED41 RS09820
gene id: 1197717:BED41_RS09820
uniprot id: A0A1B2I5T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1197717:BED41 RS01730
gene id: 1197717:BED41_RS01730
uniprot id: A0A1B2I1R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

1197717:BED41 RS00050
gene id: 1197717:BED41_RS00050
uniprot id: A0A1B2I113
names: Similarity
messages: Belongs to the peptidase M20A family.

1197717:BED41 RS03530
gene id: 1197717:BED41_RS03530
uniprot id: A0A1B2I2R5
names: Similarity
messages: Belongs to the Skp family.

1197717:BED41 RS01160
gene id: 1197717:BED41_RS01160
uniprot id: A0A1B2I1J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1197717:BED41 RS13990
gene id: 1197717:BED41_RS13990
uniprot id: A0A1B2I1Z6
names: Subcellular Location Annotation
messages: Cytoplasm

1197717:BED41 RS08935
gene id: 1197717:BED41_RS08935
uniprot id: A0A1B2I5E2
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

1197717:BED41 RS05180
gene id: 1197717:BED41_RS05180
uniprot id: A0A1B2I3H7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1197717:BED41 RS07795
gene id: 1197717:BED41_RS07795
uniprot id: A0A1B2I4Y2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1197717:BED41 RS11250
gene id: 1197717:BED41_RS11250
uniprot id: A0A1B2I6M9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1197717:BED41 RS03970
gene id: 1197717:BED41_RS03970
uniprot id: A0A1B2I2X4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1197717:BED41 RS11170
gene id: 1197717:BED41_RS11170
uniprot id: A0A1B2I6H4
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-S contributes to the protection against external stress, thus playing a role in cellular fitness and survival.

1197717:BED41 RS09080
gene id: 1197717:BED41_RS09080
uniprot id: A0A1B2I5G0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

1197717:BED41 RS13205
gene id: 1197717:BED41_RS13205
uniprot id: A0A1B2I7M5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

1197717:BED41 RS13210
gene id: 1197717:BED41_RS13210
uniprot id: A0A1B2I7M0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1197717:BED41 RS05375
gene id: 1197717:BED41_RS05375
uniprot id: A0A1B2I3P9
names: Similarity
messages: Belongs to the peptidase S33 family.

1197717:BED41 RS02150
gene id: 1197717:BED41_RS02150
uniprot id: A0A1B2I229
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1197717:BED41 RS08805
gene id: 1197717:BED41_RS08805
uniprot id: A0A1B2I5B4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1197717:BED41 RS01780
gene id: 1197717:BED41_RS01780
uniprot id: A0A1B2I1U1
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1197717:BED41 RS06945
gene id: 1197717:BED41_RS06945
uniprot id: A0A1B2I4D4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1197717:BED41 RS07200
gene id: 1197717:BED41_RS07200
uniprot id: A0A1B2I4I8
names: Similarity
messages: Belongs to the arginase family.

1197717:BED41 RS06345
gene id: 1197717:BED41_RS06345
uniprot id: A0A1B2I483
names: Similarity
messages: Belongs to the ribF family.

1197717:BED41 RS00100
gene id: 1197717:BED41_RS00100
uniprot id: A0A1B2I940
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1197717:BED41 RS13245
gene id: 1197717:BED41_RS13245
uniprot id: A0A1B2I7L6
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1197717:BED41 RS10100
gene id: 1197717:BED41_RS10100
uniprot id: A0A1B2I5X4
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS11545
gene id: 1197717:BED41_RS11545
uniprot id: A0A1B2I6S9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1197717:BED41 RS08855
gene id: 1197717:BED41_RS08855
uniprot id: A0A1B2I5B5
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS08205
gene id: 1197717:BED41_RS08205
uniprot id: A0A1B2I516
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS04460
gene id: 1197717:BED41_RS04460
uniprot id: A0A1B2I364
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1197717:BED41 RS00795
gene id: 1197717:BED41_RS00795
uniprot id: A0A1B2I1B7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1197717:BED41 RS13595
gene id: 1197717:BED41_RS13595
uniprot id: A0A1B2I7X6
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1197717:BED41 RS05725
gene id: 1197717:BED41_RS05725
uniprot id: A0A1B2I3V7
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

1197717:BED41 RS02675
gene id: 1197717:BED41_RS02675
uniprot id: A0A1B2I2C1
names: Similarity
messages: Belongs to the threonine aldolase family.

1197717:BED41 RS09645
gene id: 1197717:BED41_RS09645
uniprot id: A0A1B2I5S6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1197717:BED41 RS09610
gene id: 1197717:BED41_RS09610
uniprot id: A0A1B2I5R0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1197717:BED41 RS02700
gene id: 1197717:BED41_RS02700
uniprot id: A0A1B2I2A9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1197717:BED41 RS08815
gene id: 1197717:BED41_RS08815
uniprot id: A0A1B2I5D9
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

1197717:BED41 RS06170
gene id: 1197717:BED41_RS06170
uniprot id: A0A1B2I3Z9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1197717:BED41 RS04810
gene id: 1197717:BED41_RS04810
uniprot id: A0A1B2I3A1
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS09140
gene id: 1197717:BED41_RS09140
uniprot id: A0A1B2I5H0
names: Similarity
messages: Belongs to the TrpC family.

1197717:BED41 RS08725
gene id: 1197717:BED41_RS08725
uniprot id: A0A1B2I5B7
names: Similarity
messages: Belongs to the leucine-binding protein family.

1197717:BED41 RS01975
gene id: 1197717:BED41_RS01975
uniprot id: A0A1B2I1W8
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS05225
gene id: 1197717:BED41_RS05225
uniprot id: A0A1B2I3J7
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1197717:BED41 RS15915
gene id: 1197717:BED41_RS15915
uniprot id: A0A1B2I945
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1197717:BED41 RS09305
gene id: 1197717:BED41_RS09305
uniprot id: A0A1B2I5J9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1197717:BED41 RS09185
gene id: 1197717:BED41_RS09185
uniprot id: A0A1B2I5K3
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1197717:BED41 RS15945
gene id: 1197717:BED41_RS15945
uniprot id: A0A1B2I926
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1197717:BED41 RS04425
gene id: 1197717:BED41_RS04425
uniprot id: A0A1B2I350
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1197717:BED41 RS04390
gene id: 1197717:BED41_RS04390
uniprot id: A0A1B2I380
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

1197717:BED41 RS05205
gene id: 1197717:BED41_RS05205
uniprot id: A0A1B2I3J3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1197717:BED41 RS10820
gene id: 1197717:BED41_RS10820
uniprot id: A0A1B2I6B8
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1197717:BED41 RS06040
gene id: 1197717:BED41_RS06040
uniprot id: A0A1B2I423
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

1197717:BED41 RS15590
gene id: 1197717:BED41_RS15590
uniprot id: A0A1B2I8S7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1197717:BED41 RS06405
gene id: 1197717:BED41_RS06405
uniprot id: A0A1B2I453
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1197717:BED41 RS01055
gene id: 1197717:BED41_RS01055
uniprot id: A0A1B2I1H1
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1197717:BED41 RS10730
gene id: 1197717:BED41_RS10730
uniprot id: A0A1B2I695
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the encapsulin family. Family 1 subfamily.
messages: Encapsulin nanocompartment

1197717:BED41 RS09705
gene id: 1197717:BED41_RS09705
uniprot id: A0A1B2I5U1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1197717:BED41 RS07155
gene id: 1197717:BED41_RS07155
uniprot id: A0A1B2I4I7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1197717:BED41 RS10245
gene id: 1197717:BED41_RS10245
uniprot id: A0A1B2I601
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

1197717:BED41 RS13460
gene id: 1197717:BED41_RS13460
uniprot id: A0A1B2I7Q7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1197717:BED41 RS05865
gene id: 1197717:BED41_RS05865
uniprot id: A0A1B2I3U7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1197717:BED41 RS04500
gene id: 1197717:BED41_RS04500
uniprot id: A0A1B2I3A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1197717:BED41 RS07265
gene id: 1197717:BED41_RS07265
uniprot id: A0A1B2I4J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1197717:BED41 RS09630
gene id: 1197717:BED41_RS09630
uniprot id: A0A1B2I5S1
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1197717:BED41 RS07540
gene id: 1197717:BED41_RS07540
uniprot id: A0A1B2I4M9
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS11005
gene id: 1197717:BED41_RS11005
uniprot id: A0A1B2I6G3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1197717:BED41 RS10705
gene id: 1197717:BED41_RS10705
uniprot id: A0A1B2I6C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1197717:BED41 RS09995
gene id: 1197717:BED41_RS09995
uniprot id: A0A1B2I5Y1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1197717:BED41 RS09680
gene id: 1197717:BED41_RS09680
uniprot id: A0A1B2I5T2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1197717:BED41 RS00350
gene id: 1197717:BED41_RS00350
uniprot id: A0A1B2I158
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

1197717:BED41 RS08025
gene id: 1197717:BED41_RS08025
uniprot id: A0A1B2I4Y4
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1197717:BED41 RS08075
gene id: 1197717:BED41_RS08075
uniprot id: A0A1B2I4Z5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1197717:BED41 RS09295
gene id: 1197717:BED41_RS09295
uniprot id: A0A1B2I5L4
names: Similarity
messages: Belongs to the ycf81 family.

1197717:BED41 RS09290
gene id: 1197717:BED41_RS09290
uniprot id: A0A1B2I5J8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS12975
gene id: 1197717:BED41_RS12975
uniprot id: A0A1B2I7H6
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS07455
gene id: 1197717:BED41_RS07455
uniprot id: A0A1B2I4Q5
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.

1197717:BED41 RS07270
gene id: 1197717:BED41_RS07270
uniprot id: A0A1B2I4I4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS09785
gene id: 1197717:BED41_RS09785
uniprot id: A0A1B2I5V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1197717:BED41 RS01010
gene id: 1197717:BED41_RS01010
uniprot id: A0A1B2I1F1
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1197717:BED41 RS11375
gene id: 1197717:BED41_RS11375
uniprot id: A0A1B2I6M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1197717:BED41 RS09960
gene id: 1197717:BED41_RS09960
uniprot id: A0A1B2I5V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1197717:BED41 RS11155
gene id: 1197717:BED41_RS11155
uniprot id: A0A1B2I6G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1197717:BED41 RS06435
gene id: 1197717:BED41_RS06435
uniprot id: A0A1B2I488
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS07445
gene id: 1197717:BED41_RS07445
uniprot id: A0A1B2I4M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane

1197717:BED41 RS10765
gene id: 1197717:BED41_RS10765
uniprot id: A0A1B2I6A0
names: Function
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.

1197717:BED41 RS11490
gene id: 1197717:BED41_RS11490
uniprot id: A0A1B2I6S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1197717:BED41 RS01145
gene id: 1197717:BED41_RS01145
uniprot id: A0A1B2I1K9
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS15660
gene id: 1197717:BED41_RS15660
uniprot id: A0A1B2I9U7
names: Similarity
messages: Belongs to the UPF0251 family.

1197717:BED41 RS06050
gene id: 1197717:BED41_RS06050
uniprot id: A0A1B2I3Z5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1197717:BED41 RS11900
gene id: 1197717:BED41_RS11900
uniprot id: A0A1B2I6X0
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1197717:BED41 RS02795
gene id: 1197717:BED41_RS02795
uniprot id: A0A1B2I2B0
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS15200
gene id: 1197717:BED41_RS15200
uniprot id: A0A1B2I8R3
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1197717:BED41 RS12100
gene id: 1197717:BED41_RS12100
uniprot id: A0A1B2I744
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS06530
gene id: 1197717:BED41_RS06530
uniprot id: A0A1B2I473
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

1197717:BED41 RS00065
gene id: 1197717:BED41_RS00065
uniprot id: A0A1B2I0Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1197717:BED41 RS08020
gene id: 1197717:BED41_RS08020
uniprot id: A0A1B2I4X8
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the LacAB/RpiB family.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1197717:BED41 RS05605
gene id: 1197717:BED41_RS05605
uniprot id: A0A1B2I3Q3
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS06525
gene id: 1197717:BED41_RS06525
uniprot id: A0A1B2I4B2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1197717:BED41 RS04930
gene id: 1197717:BED41_RS04930
uniprot id: A0A1B2I3E7
names: Similarity
messages: Belongs to the class-I fumarase family.

1197717:BED41 RS09675
gene id: 1197717:BED41_RS09675
uniprot id: A0A1B2I5R6
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1197717:BED41 RS00360
gene id: 1197717:BED41_RS00360
uniprot id: A0A1B2I143
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1197717:BED41 RS00820
gene id: 1197717:BED41_RS00820
uniprot id: A0A1B2I1C1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1197717:BED41 RS02525
gene id: 1197717:BED41_RS02525
uniprot id: A0A1B2I281
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1197717:BED41 RS13890
gene id: 1197717:BED41_RS13890
uniprot id: A0A1B2I7Z4
names: Similarity
messages: Belongs to the group II decarboxylase family.

1197717:BED41 RS15430
gene id: 1197717:BED41_RS15430
uniprot id: A0A1B2I8Q6
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1197717:BED41 RS00075
gene id: 1197717:BED41_RS00075
uniprot id: A0A1B2I0Z1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS04685
gene id: 1197717:BED41_RS04685
uniprot id: A0A1B2I3A4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

1197717:BED41 RS02070
gene id: 1197717:BED41_RS02070
uniprot id: A0A1B2I1Y5
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

1197717:BED41 RS09655
gene id: 1197717:BED41_RS09655
uniprot id: A0A1B2I5Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
messages: Cell surface

1197717:BED41 RS05125
gene id: 1197717:BED41_RS05125
uniprot id: A0A1B2I3H6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1197717:BED41 RS12945
gene id: 1197717:BED41_RS12945
uniprot id: A0A1B2I7H1
names: Similarity
messages: Belongs to the PRORSD1 family.

1197717:BED41 RS11875
gene id: 1197717:BED41_RS11875
uniprot id: A0A1B2I6X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane

1197717:BED41 RS12065
gene id: 1197717:BED41_RS12065
uniprot id: A0A1B2I705
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1197717:BED41 RS03715
gene id: 1197717:BED41_RS03715
uniprot id: A0A1B2I2U2
names: Similarity
messages: Belongs to the peptidase M13 family.

1197717:BED41 RS01815
gene id: 1197717:BED41_RS01815
uniprot id: A0A1B2I1X2
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase family.

1197717:BED41 RS01340
gene id: 1197717:BED41_RS01340
uniprot id: A0A1B2I1K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1197717:BED41 RS14065
gene id: 1197717:BED41_RS14065
uniprot id: A0A1B2I830
names: Similarity
messages: Belongs to the class-I fumarase family.

1197717:BED41 RS10160
gene id: 1197717:BED41_RS10160
uniprot id: A0A1B2I618
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1197717:BED41 RS06910
gene id: 1197717:BED41_RS06910
uniprot id: A0A1B2I9I6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1197717:BED41 RS10720
gene id: 1197717:BED41_RS10720
uniprot id: A0A1B2I694
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

1197717:BED41 RS05790
gene id: 1197717:BED41_RS05790
uniprot id: A0A1B2I3T9
names: Function
names: Similarity
messages: Abolishes the inhibitory effect of tetracyclin on protein synthesis by a non-covalent modification of the ribosomes.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

1197717:BED41 RS04335
gene id: 1197717:BED41_RS04335
uniprot id: A0A1B2I363
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS11780
gene id: 1197717:BED41_RS11780
uniprot id: A0A1B2I6U9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

1197717:BED41 RS12075
gene id: 1197717:BED41_RS12075
uniprot id: A0A1B2I6Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1197717:BED41 RS14885
gene id: 1197717:BED41_RS14885
uniprot id: A0A1B2I8I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1197717:BED41 RS15315
gene id: 1197717:BED41_RS15315
uniprot id: A0A1B2I8S3
names: Similarity
messages: Belongs to the DtxR/MntR family.

1197717:BED41 RS05910
gene id: 1197717:BED41_RS05910
uniprot id: A0A1B2I3W0
names: Similarity
messages: Belongs to the UPF0758 family.

1197717:BED41 RS10685
gene id: 1197717:BED41_RS10685
uniprot id: A0A1B2I6B5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1197717:BED41 RS09250
gene id: 1197717:BED41_RS09250
uniprot id: A0A1B2I5J0
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS03980
gene id: 1197717:BED41_RS03980
uniprot id: A0A1B2I2W3
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

1197717:BED41 RS06305
gene id: 1197717:BED41_RS06305
uniprot id: A0A1B2I437
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1197717:BED41 RS13315
gene id: 1197717:BED41_RS13315
uniprot id: A0A1B2I7N5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1197717:BED41 RS14295
gene id: 1197717:BED41_RS14295
uniprot id: A0A1B2I888
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS07590
gene id: 1197717:BED41_RS07590
uniprot id: A0A1B2I4U0
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1197717:BED41 RS15080
gene id: 1197717:BED41_RS15080
uniprot id: A0A1B2I8K0
names: Function
messages: Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase.

1197717:BED41 RS11355
gene id: 1197717:BED41_RS11355
uniprot id: A0A1B2I6N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

1197717:BED41 RS08980
gene id: 1197717:BED41_RS08980
uniprot id: A0A1B2I5G6
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

1197717:BED41 RS13935
gene id: 1197717:BED41_RS13935
uniprot id: A0A1B2I7Z5
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS05175
gene id: 1197717:BED41_RS05175
uniprot id: A0A1B2I3I6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1197717:BED41 RS04910
gene id: 1197717:BED41_RS04910
uniprot id: A0A1B2I3F9
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1197717:BED41 RS14960
gene id: 1197717:BED41_RS14960
uniprot id: A0A1B2I8J7
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS14525
gene id: 1197717:BED41_RS14525
uniprot id: A0A1B2I894
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS07505
gene id: 1197717:BED41_RS07505
uniprot id: A0A1B2I4P0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1197717:BED41 RS05245
gene id: 1197717:BED41_RS05245
uniprot id: A0A1B2I3I8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS15495
gene id: 1197717:BED41_RS15495
uniprot id: A0A1B2I8V2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1197717:BED41 RS00650
gene id: 1197717:BED41_RS00650
uniprot id: A0A1B2I964
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS13510
gene id: 1197717:BED41_RS13510
uniprot id: A0A1B2I7R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1197717:BED41 RS04000
gene id: 1197717:BED41_RS04000
uniprot id: A0A1B2I2X6
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS10070
gene id: 1197717:BED41_RS10070
uniprot id: A0A1B2I5X1
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS07985
gene id: 1197717:BED41_RS07985
uniprot id: A0A1B2I9I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1197717:BED41 RS11230
gene id: 1197717:BED41_RS11230
uniprot id: A0A1B2I6L7
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1197717:BED41 RS13100
gene id: 1197717:BED41_RS13100
uniprot id: A0A1B2I7L1
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS07570
gene id: 1197717:BED41_RS07570
uniprot id: A0A1B2I9G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1197717:BED41 RS12705
gene id: 1197717:BED41_RS12705
uniprot id: A0A1B2I7B7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1197717:BED41 RS03525
gene id: 1197717:BED41_RS03525
uniprot id: A0A1B2I2N5
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1197717:BED41 RS04130
gene id: 1197717:BED41_RS04130
uniprot id: A0A1B2I328
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

1197717:BED41 RS13280
gene id: 1197717:BED41_RS13280
uniprot id: A0A1B2I7R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1197717:BED41 RS07900
gene id: 1197717:BED41_RS07900
uniprot id: A0A1B2I4Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1197717:BED41 RS14405
gene id: 1197717:BED41_RS14405
uniprot id: A0A1B2I8A6
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1197717:BED41 RS13130
gene id: 1197717:BED41_RS13130
uniprot id: A0A1B2I7K0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

1197717:BED41 RS13975
gene id: 1197717:BED41_RS13975
uniprot id: A0A1B2I800
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

1197717:BED41 RS15865
gene id: 1197717:BED41_RS15865
uniprot id: A0A1B2I938
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1197717:BED41 RS05285
gene id: 1197717:BED41_RS05285
uniprot id: A0A1B2I3L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1197717:BED41 RS06825
gene id: 1197717:BED41_RS06825
uniprot id: A0A1B2I4D8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS07335
gene id: 1197717:BED41_RS07335
uniprot id: A0A1B2I4J4
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-S contributes to the protection against external stress, thus playing a role in cellular fitness and survival.

1197717:BED41 RS00020
gene id: 1197717:BED41_RS00020
uniprot id: A0A1B2I0Y6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1197717:BED41 RS01440
gene id: 1197717:BED41_RS01440
uniprot id: A0A1B2I1L7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1197717:BED41 RS14060
gene id: 1197717:BED41_RS14060
uniprot id: A0A1B2I821
names: Similarity
messages: Belongs to the class-I fumarase family.

1197717:BED41 RS14745
gene id: 1197717:BED41_RS14745
uniprot id: A0A1B2I8C3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1197717:BED41 RS10105
gene id: 1197717:BED41_RS10105
uniprot id: A0A1B2I5Y4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1197717:BED41 RS15400
gene id: 1197717:BED41_RS15400
uniprot id: A0A1B2I8U4
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1197717:BED41 RS09345
gene id: 1197717:BED41_RS09345
uniprot id: A0A1B2I5M3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1197717:BED41 RS13825
gene id: 1197717:BED41_RS13825
uniprot id: A0A1B2I7Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1197717:BED41 RS10170
gene id: 1197717:BED41_RS10170
uniprot id: A0A1B2I5Z1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

1197717:BED41 RS02320
gene id: 1197717:BED41_RS02320
uniprot id: A0A1B2I968
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS04235
gene id: 1197717:BED41_RS04235
uniprot id: A0A1B2I303
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1197717:BED41 RS06550
gene id: 1197717:BED41_RS06550
uniprot id: A0A1B2I466
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

1197717:BED41 RS15455
gene id: 1197717:BED41_RS15455
uniprot id: A0A1B2I8V4
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

1197717:BED41 RS08620
gene id: 1197717:BED41_RS08620
uniprot id: A0A1B2I582
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1197717:BED41 RS05210
gene id: 1197717:BED41_RS05210
uniprot id: A0A1B2I3H8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1197717:BED41 RS06995
gene id: 1197717:BED41_RS06995
uniprot id: A0A1B2I4E7
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS10215
gene id: 1197717:BED41_RS10215
uniprot id: A0A1B2I630
names: Similarity
messages: Belongs to the KdgT transporter family.

1197717:BED41 RS06590
gene id: 1197717:BED41_RS06590
uniprot id: A0A1B2I485
names: Similarity
names: Subunit
messages: Belongs to the MtrB family.
messages: Oligomer of 11 identical subunits arranged in doughnut-like structure.

1197717:BED41 RS05200
gene id: 1197717:BED41_RS05200
uniprot id: A0A1B2I3J5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1197717:BED41 RS09335
gene id: 1197717:BED41_RS09335
uniprot id: A0A1B2I5L7
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1197717:BED41 RS12970
gene id: 1197717:BED41_RS12970
uniprot id: A0A1B2I7H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family.
messages: Cell membrane
messages: Membrane

1197717:BED41 RS11120
gene id: 1197717:BED41_RS11120
uniprot id: A0A1B2I6H0
names: Similarity
messages: Belongs to the Lgt family.

1197717:BED41 RS00010
gene id: 1197717:BED41_RS00010
uniprot id: A0A1B2I0Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1197717:BED41 RS09855
gene id: 1197717:BED41_RS09855
uniprot id: A0A1B2I5U2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1197717:BED41 RS07525
gene id: 1197717:BED41_RS07525
uniprot id: A0A1B2I4P5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1197717:BED41 RS15385
gene id: 1197717:BED41_RS15385
uniprot id: A0A1B2I8T3
names: Similarity
messages: Belongs to the CobH/CbiC family.

1197717:BED41 RS03810
gene id: 1197717:BED41_RS03810
uniprot id: A0A1B2I2T5
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS14355
gene id: 1197717:BED41_RS14355
uniprot id: A0A1B2I8B4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.

1197717:BED41 RS13025
gene id: 1197717:BED41_RS13025
uniprot id: A0A1B2I7I6
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS08740
gene id: 1197717:BED41_RS08740
uniprot id: A0A1B2I598
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

1197717:BED41 RS15805
gene id: 1197717:BED41_RS15805
uniprot id: A0A1B2I917
names: Similarity
messages: Belongs to the glutamine synthetase family.

1197717:BED41 RS09695
gene id: 1197717:BED41_RS09695
uniprot id: A0A1B2I5R3
names: Similarity
messages: Belongs to the asp23 family.

1197717:BED41 RS04985
gene id: 1197717:BED41_RS04985
uniprot id: A0A1B2I3F2
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS03565
gene id: 1197717:BED41_RS03565
uniprot id: A0A1B2I2Q4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1197717:BED41 RS15245
gene id: 1197717:BED41_RS15245
uniprot id: A0A1B2I8M3
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS13340
gene id: 1197717:BED41_RS13340
uniprot id: J9ZY93
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1197717:BED41 RS01705
gene id: 1197717:BED41_RS01705
uniprot id: A0A1B2I1S7
names: Similarity
messages: Belongs to the serpin family.

1197717:BED41 RS15110
gene id: 1197717:BED41_RS15110
uniprot id: A0A1B2I8M2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1197717:BED41 RS05240
gene id: 1197717:BED41_RS05240
uniprot id: A0A1B2I3N2
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS15390
gene id: 1197717:BED41_RS15390
uniprot id: A0A1B2I8S9
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

1197717:BED41 RS10890
gene id: 1197717:BED41_RS10890
uniprot id: A0A1B2I6C8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1197717:BED41 RS00925
gene id: 1197717:BED41_RS00925
uniprot id: A0A1B2I1D8
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1197717:BED41 RS03210
gene id: 1197717:BED41_RS03210
uniprot id: A0A1B2I158
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

1197717:BED41 RS03505
gene id: 1197717:BED41_RS03505
uniprot id: A0A1B2I2R7
names: Similarity
messages: Belongs to the YoeB family.

1197717:BED41 RS03825
gene id: 1197717:BED41_RS03825
uniprot id: A0A1B2I2T6
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS14490
gene id: 1197717:BED41_RS14490
uniprot id: A0A1B2I8B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1197717:BED41 RS12040
gene id: 1197717:BED41_RS12040
uniprot id: A0A1B2I700
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1197717:BED41 RS03175
gene id: 1197717:BED41_RS03175
uniprot id: A0A1B2I2J2
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1197717:BED41 RS06835
gene id: 1197717:BED41_RS06835
uniprot id: A0A1B2I9F9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1197717:BED41 RS08735
gene id: 1197717:BED41_RS08735
uniprot id: A0A1B2I5A0
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS11140
gene id: 1197717:BED41_RS11140
uniprot id: A0A1B2I9N4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1197717:BED41 RS15095
gene id: 1197717:BED41_RS15095
uniprot id: A0A1B2I8M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1197717:BED41 RS08685
gene id: 1197717:BED41_RS08685
uniprot id: A0A1B2I587
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS14925
gene id: 1197717:BED41_RS14925
uniprot id: A0A1B2I8G5
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS05190
gene id: 1197717:BED41_RS05190
uniprot id: A0A1B2I3L7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1197717:BED41 RS08505
gene id: 1197717:BED41_RS08505
uniprot id: A0A1B2I558
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1197717:BED41 RS07600
gene id: 1197717:BED41_RS07600
uniprot id: A0A1B2I4Q2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1197717:BED41 RS07750
gene id: 1197717:BED41_RS07750
uniprot id: A0A1B2I4T0
names: Similarity
messages: Belongs to the TlyA family.

1197717:BED41 RS15975
gene id: 1197717:BED41_RS15975
uniprot id: A0A1B2I930
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1197717:BED41 RS01435
gene id: 1197717:BED41_RS01435
uniprot id: A0A1B2I1Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1197717:BED41 RS14000
gene id: 1197717:BED41_RS14000
uniprot id: A0A1B2I1Z1
names: Subcellular Location Annotation
messages: Cytoplasm

1197717:BED41 RS04895
gene id: 1197717:BED41_RS04895
uniprot id: A0A1B2I3D7
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS13800
gene id: 1197717:BED41_RS13800
uniprot id: A0A1B2I7X2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1197717:BED41 RS09935
gene id: 1197717:BED41_RS09935
uniprot id: A0A1B2I5Y7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS08230
gene id: 1197717:BED41_RS08230
uniprot id: A0A1B2I549
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

1197717:BED41 RS07470
gene id: 1197717:BED41_RS07470
uniprot id: A0A1B2I4N8
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

1197717:BED41 RS02980
gene id: 1197717:BED41_RS02980
uniprot id: A0A1B2I2E2
names: Similarity
messages: Belongs to the PrpD family.

1197717:BED41 RS04560
gene id: 1197717:BED41_RS04560
uniprot id: A0A1B2I3B0
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1197717:BED41 RS10185
gene id: 1197717:BED41_RS10185
uniprot id: A0A1B2I5Z4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1197717:BED41 RS02810
gene id: 1197717:BED41_RS02810
uniprot id: A0A1B2I2C3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1197717:BED41 RS11565
gene id: 1197717:BED41_RS11565
uniprot id: A0A1B2I6T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1197717:BED41 RS09385
gene id: 1197717:BED41_RS09385
uniprot id: A0A1B2I9H2
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1197717:BED41 RS01900
gene id: 1197717:BED41_RS01900
uniprot id: A0A1B2I1W5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1197717:BED41 RS02860
gene id: 1197717:BED41_RS02860
uniprot id: A0A1B2I2D1
names: Similarity
messages: Belongs to the DapB family.

1197717:BED41 RS08745
gene id: 1197717:BED41_RS08745
uniprot id: A0A1B2I5A9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

1197717:BED41 RS11000
gene id: 1197717:BED41_RS11000
uniprot id: A0A1B2I6I3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1197717:BED41 RS01845
gene id: 1197717:BED41_RS01845
uniprot id: A0A1B2I1V6
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1197717:BED41 RS01710
gene id: 1197717:BED41_RS01710
uniprot id: A0A1B2I1V2
names: Similarity
messages: Belongs to the serpin family.

1197717:BED41 RS05090
gene id: 1197717:BED41_RS05090
uniprot id: A0A1B2I3J2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1197717:BED41 RS02940
gene id: 1197717:BED41_RS02940
uniprot id: A0A1B2I2E5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M38 family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the hydrolytic cleavage of a subset of L-isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation.
messages: Cytoplasm

1197717:BED41 RS11530
gene id: 1197717:BED41_RS11530
uniprot id: A0A1B2I6R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1197717:BED41 RS14275
gene id: 1197717:BED41_RS14275
uniprot id: A0A1B2I869
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

1197717:BED41 RS13295
gene id: 1197717:BED41_RS13295
uniprot id: A0A1B2I7M8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1197717:BED41 RS12465
gene id: 1197717:BED41_RS12465
uniprot id: A0A1B2I791
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS13010
gene id: 1197717:BED41_RS13010
uniprot id: A0A1B2I7H4
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1197717:BED41 RS04610
gene id: 1197717:BED41_RS04610
uniprot id: A0A1B2I3A9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1197717:BED41 RS11295
gene id: 1197717:BED41_RS11295
uniprot id: A0A1B2I6M5
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS10055
gene id: 1197717:BED41_RS10055
uniprot id: A0A1B2I5Z8
names: Function
names: Similarity
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.

1197717:BED41 RS05880
gene id: 1197717:BED41_RS05880
uniprot id: A0A1B2I3V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1197717:BED41 RS00980
gene id: 1197717:BED41_RS00980
uniprot id: A0A1B2I1E9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1197717:BED41 RS14965
gene id: 1197717:BED41_RS14965
uniprot id: A0A1B2I8L9
names: Similarity
messages: Belongs to the CdaR family.

1197717:BED41 RS09505
gene id: 1197717:BED41_RS09505
uniprot id: A0A1B2I5N7
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

1197717:BED41 RS02085
gene id: 1197717:BED41_RS02085
uniprot id: A0A1B2I222
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

1197717:BED41 RS00670
gene id: 1197717:BED41_RS00670
uniprot id: A0A1B2I1A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

1197717:BED41 RS15935
gene id: 1197717:BED41_RS15935
uniprot id: A0A1B2I8Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1197717:BED41 RS09685
gene id: 1197717:BED41_RS09685
uniprot id: A0A1B2I9L3
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1197717:BED41 RS06850
gene id: 1197717:BED41_RS06850
uniprot id: A0A1B2I4C2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1197717:BED41 RS13330
gene id: 1197717:BED41_RS13330
uniprot id: A0A1B2I7S4
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1197717:BED41 RS08250
gene id: 1197717:BED41_RS08250
uniprot id: A0A1B2I531
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1197717:BED41 RS04420
gene id: 1197717:BED41_RS04420
uniprot id: A0A1B2I358
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1197717:BED41 RS13565
gene id: 1197717:BED41_RS13565
uniprot id: A0A1B2I7U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1197717:BED41 RS03030
gene id: 1197717:BED41_RS03030
uniprot id: A0A1B2I2F4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1197717:BED41 RS01790
gene id: 1197717:BED41_RS01790
uniprot id: A0A1B2I1U9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS07995
gene id: 1197717:BED41_RS07995
uniprot id: A0A1B2I4X9
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

1197717:BED41 RS05290
gene id: 1197717:BED41_RS05290
uniprot id: A0A1B2I3P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1197717:BED41 RS14410
gene id: 1197717:BED41_RS14410
uniprot id: A0A1B2I8E3
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS01620
gene id: 1197717:BED41_RS01620
uniprot id: A0A1B2I1R1
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS15115
gene id: 1197717:BED41_RS15115
uniprot id: A0A1B2I8L0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1197717:BED41 RS12260
gene id: 1197717:BED41_RS12260
uniprot id: A0A1B2I751
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1197717:BED41 RS09730
gene id: 1197717:BED41_RS09730
uniprot id: A0A1B2I5S7
names: Similarity
messages: Belongs to the bacterial secretin family.

1197717:BED41 RS07015
gene id: 1197717:BED41_RS07015
uniprot id: A0A1B2I4F2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1197717:BED41 RS04370
gene id: 1197717:BED41_RS04370
uniprot id: A0A1B2I347
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS02395
gene id: 1197717:BED41_RS02395
uniprot id: A0A1B2I232
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS10310
gene id: 1197717:BED41_RS10310
uniprot id: A0A1B2I616
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1197717:BED41 RS14050
gene id: 1197717:BED41_RS14050
uniprot id: A0A1B2I831
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate ammonia-lyase family.
messages: Homodimer.

1197717:BED41 RS12545
gene id: 1197717:BED41_RS12545
uniprot id: A0A1B2I792
names: Subcellular Location Annotation
messages: Cytoplasm

1197717:BED41 RS09115
gene id: 1197717:BED41_RS09115
uniprot id: A0A1B2I5H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1197717:BED41 RS10835
gene id: 1197717:BED41_RS10835
uniprot id: A0A1B2I6B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1197717:BED41 RS02575
gene id: 1197717:BED41_RS02575
uniprot id: A0A1B2I285
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS05015
gene id: 1197717:BED41_RS05015
uniprot id: A0A1B2I3I3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1197717:BED41 RS14260
gene id: 1197717:BED41_RS14260
uniprot id: A0A1B2I857
names: Subunit
messages: Homotetramer.

1197717:BED41 RS10745
gene id: 1197717:BED41_RS10745
uniprot id: A0A1B2I6B3
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS06745
gene id: 1197717:BED41_RS06745
uniprot id: A0A1B2I4C9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1197717:BED41 RS15450
gene id: 1197717:BED41_RS15450
uniprot id: A0A1B2I8Q1
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

1197717:BED41 RS15910
gene id: 1197717:BED41_RS15910
uniprot id: A0A1B2I921
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1197717:BED41 RS08300
gene id: 1197717:BED41_RS08300
uniprot id: A0A1B2I556
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1197717:BED41 RS00290
gene id: 1197717:BED41_RS00290
uniprot id: A0A1B2I142
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1197717:BED41 RS12110
gene id: 1197717:BED41_RS12110
uniprot id: A0A1B2I709
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1197717:BED41 RS07550
gene id: 1197717:BED41_RS07550
uniprot id: A0A1B2I4P2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1197717:BED41 RS13430
gene id: 1197717:BED41_RS13430
uniprot id: A0A1B2I7Q9
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1197717:BED41 RS05110
gene id: 1197717:BED41_RS05110
uniprot id: A0A1B2I3F8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1197717:BED41 RS01955
gene id: 1197717:BED41_RS01955
uniprot id: A0A1B2I1W4
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS04565
gene id: 1197717:BED41_RS04565
uniprot id: A0A1B2I372
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1197717:BED41 RS11870
gene id: 1197717:BED41_RS11870
uniprot id: A0A1B2I6Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

1197717:BED41 RS15635
gene id: 1197717:BED41_RS15635
uniprot id: A0A1B2I8Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1197717:BED41 RS12780
gene id: 1197717:BED41_RS12780
uniprot id: A0A1B2I7E0
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1197717:BED41 RS13950
gene id: 1197717:BED41_RS13950
uniprot id: A0A1B2I812
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1197717:BED41 RS07630
gene id: 1197717:BED41_RS07630
uniprot id: A0A1B2I4P1
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

1197717:BED41 RS03695
gene id: 1197717:BED41_RS03695
uniprot id: A0A1B2I2S3
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS02295
gene id: 1197717:BED41_RS02295
uniprot id: A0A1B2I226
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

1197717:BED41 RS01670
gene id: 1197717:BED41_RS01670
uniprot id: A0A1B2I1S1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1197717:BED41 RS03660
gene id: 1197717:BED41_RS03660
uniprot id: A0A1B2I2Q5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1197717:BED41 RS13425
gene id: 1197717:BED41_RS13425
uniprot id: A0A1B2I8N9
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1197717:BED41 RS08625
gene id: 1197717:BED41_RS08625
uniprot id: A0A1B2I579
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1197717:BED41 RS11245
gene id: 1197717:BED41_RS11245
uniprot id: A0A1B2I6L5
names: Similarity
messages: Belongs to the serpin family.

1197717:BED41 RS04025
gene id: 1197717:BED41_RS04025
uniprot id: A0A1B2I308
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1197717:BED41 RS04300
gene id: 1197717:BED41_RS04300
uniprot id: A0A1B2I330
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OadG family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane

1197717:BED41 RS04310
gene id: 1197717:BED41_RS04310
uniprot id: A0A1B2I326
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1197717:BED41 RS14795
gene id: 1197717:BED41_RS14795
uniprot id: A0A1B2I8D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1197717:BED41 RS08535
gene id: 1197717:BED41_RS08535
uniprot id: A0A1B2I560
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1197717:BED41 RS14665
gene id: 1197717:BED41_RS14665
uniprot id: A0A1B2I8C7
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS01150
gene id: 1197717:BED41_RS01150
uniprot id: A0A1B2I1H7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1197717:BED41 RS00125
gene id: 1197717:BED41_RS00125
uniprot id: A0A1B2I102
names: Similarity
messages: Belongs to the IMPACT family.

1197717:BED41 RS05135
gene id: 1197717:BED41_RS05135
uniprot id: A0A1B2I3I1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1197717:BED41 RS11855
gene id: 1197717:BED41_RS11855
uniprot id: A0A1B2I6W7
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1197717:BED41 RS07790
gene id: 1197717:BED41_RS07790
uniprot id: A0A1B2I4U8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1197717:BED41 RS15120
gene id: 1197717:BED41_RS15120
uniprot id: A0A1B2I8N4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1197717:BED41 RS03720
gene id: 1197717:BED41_RS03720
uniprot id: A0A1B2I2U0
names: Similarity
messages: Belongs to the peptidase M20A family.

1197717:BED41 RS13505
gene id: 1197717:BED41_RS13505
uniprot id: A0A1B2I7S7
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1197717:BED41 RS04260
gene id: 1197717:BED41_RS04260
uniprot id: A0A1B2I327
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS13855
gene id: 1197717:BED41_RS13855
uniprot id: A0A1B2I7Y2
names: Similarity
messages: Belongs to the CdaR family.

1197717:BED41 RS14325
gene id: 1197717:BED41_RS14325
uniprot id: A0A1B2I883
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

1197717:BED41 RS00015
gene id: 1197717:BED41_RS00015
uniprot id: A0A1B2I0W0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1197717:BED41 RS03015
gene id: 1197717:BED41_RS03015
uniprot id: A0A1B2I2H9
names: Similarity
messages: Belongs to the IlvD/Edd family.

1197717:BED41 RS05845
gene id: 1197717:BED41_RS05845
uniprot id: A0A1B2I3U9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1197717:BED41 RS04100
gene id: 1197717:BED41_RS04100
uniprot id: A0A1B2I2Y5
names: Similarity
messages: Belongs to the YoeB family.

1197717:BED41 RS08240
gene id: 1197717:BED41_RS08240
uniprot id: A0A1B2I517
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1197717:BED41 RS07450
gene id: 1197717:BED41_RS07450
uniprot id: A0A1B2I4N4
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

1197717:BED41 RS06970
gene id: 1197717:BED41_RS06970
uniprot id: A0A1B2I4F8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS13000
gene id: 1197717:BED41_RS13000
uniprot id: A0A1B2I7J2
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

1197717:BED41 RS04060
gene id: 1197717:BED41_RS04060
uniprot id: A0A1B2I2Y6
names: Caution
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS14590
gene id: 1197717:BED41_RS14590
uniprot id: A0A1B2I8B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1197717:BED41 RS13575
gene id: 1197717:BED41_RS13575
uniprot id: A0A1B2I7U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1197717:BED41 RS14930
gene id: 1197717:BED41_RS14930
uniprot id: A0A1B2I8J9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1197717:BED41 RS13895
gene id: 1197717:BED41_RS13895
uniprot id: A0A1B2I803
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS15930
gene id: 1197717:BED41_RS15930
uniprot id: A0A1B2I904
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1197717:BED41 RS14790
gene id: 1197717:BED41_RS14790
uniprot id: A0A1B2I8K1
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1197717:BED41 RS00175
gene id: 1197717:BED41_RS00175
uniprot id: A0A1B2I121
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1197717:BED41 RS10270
gene id: 1197717:BED41_RS10270
uniprot id: A0A1B2I640
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1197717:BED41 RS05255
gene id: 1197717:BED41_RS05255
uniprot id: A0A1B2I3K0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1197717:BED41 RS00465
gene id: 1197717:BED41_RS00465
uniprot id: A0A1B2I160
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

1197717:BED41 RS04650
gene id: 1197717:BED41_RS04650
uniprot id: A0A1B2I397
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1197717:BED41 RS12750
gene id: 1197717:BED41_RS12750
uniprot id: A0A1B2I7D6
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS14905
gene id: 1197717:BED41_RS14905
uniprot id: A0A1B2I8H2
names: Similarity
messages: Belongs to the peptidase M20A family.

1197717:BED41 RS12710
gene id: 1197717:BED41_RS12710
uniprot id: A0A1B2I7C1
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS11600
gene id: 1197717:BED41_RS11600
uniprot id: A0A1B2I6S4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1197717:BED41 RS11265
gene id: 1197717:BED41_RS11265
uniprot id: A0A1B2I6K9
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS02260
gene id: 1197717:BED41_RS02260
uniprot id: A0A1B2I250
names: Similarity
messages: Belongs to the Fur family.

1197717:BED41 RS10950
gene id: 1197717:BED41_RS10950
uniprot id: A0A1B2I6F3
names: Similarity
messages: Belongs to the Skp family.

1197717:BED41 RS01750
gene id: 1197717:BED41_RS01750
uniprot id: A0A1B2I1S4
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1197717:BED41 RS01310
gene id: 1197717:BED41_RS01310
uniprot id: A0A1B2I1J8
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS01395
gene id: 1197717:BED41_RS01395
uniprot id: A0A1B2I948
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1197717:BED41 RS11705
gene id: 1197717:BED41_RS11705
uniprot id: A0A1B2I6T0
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS10315
gene id: 1197717:BED41_RS10315
uniprot id: A0A1B2I623
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1197717:BED41 RS03580
gene id: 1197717:BED41_RS03580
uniprot id: A0A1B2I2S5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1197717:BED41 RS09095
gene id: 1197717:BED41_RS09095
uniprot id: A0A1B2I5F8
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1197717:BED41 RS06905
gene id: 1197717:BED41_RS06905
uniprot id: A0A1B2I4D2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1197717:BED41 RS01050
gene id: 1197717:BED41_RS01050
uniprot id: A0A1B2I1I2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS15470
gene id: 1197717:BED41_RS15470
uniprot id: A0A1B2I8R0
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS15595
gene id: 1197717:BED41_RS15595
uniprot id: A0A1B2I8U9
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS01015
gene id: 1197717:BED41_RS01015
uniprot id: A0A1B2I1F3
names: Similarity
messages: Belongs to the Fur family.

1197717:BED41 RS01595
gene id: 1197717:BED41_RS01595
uniprot id: A0A1B2I1P3
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1197717:BED41 RS12185
gene id: 1197717:BED41_RS12185
uniprot id: A0A1B2I746
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS01240
gene id: 1197717:BED41_RS01240
uniprot id: A0A1B2I1J3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1197717:BED41 RS06395
gene id: 1197717:BED41_RS06395
uniprot id: A0A1B2I490
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1197717:BED41 RS02680
gene id: 1197717:BED41_RS02680
uniprot id: A0A1B2I287
names: Similarity
messages: Belongs to the peptidase U62 family.

1197717:BED41 RS08610
gene id: 1197717:BED41_RS08610
uniprot id: A0A1B2I5A4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1197717:BED41 RS15965
gene id: 1197717:BED41_RS15965
uniprot id: A0A1B2I946
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1197717:BED41 RS03730
gene id: 1197717:BED41_RS03730
uniprot id: A0A1B2I2R2
names: Similarity
messages: Belongs to the peptidase M20A family.

1197717:BED41 RS13450
gene id: 1197717:BED41_RS13450
uniprot id: A0A1B2I7Q3
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1197717:BED41 RS08050
gene id: 1197717:BED41_RS08050
uniprot id: A0A1B2I4X4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1197717:BED41 RS04860
gene id: 1197717:BED41_RS04860
uniprot id: A0A1B2I3G5
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.

1197717:BED41 RS14845
gene id: 1197717:BED41_RS14845
uniprot id: A0A1B2I8E2
names: Similarity
messages: Belongs to the proline racemase family.

1197717:BED41 RS14125
gene id: 1197717:BED41_RS14125
uniprot id: A0A1B2I9T5
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

1197717:BED41 RS14075
gene id: 1197717:BED41_RS14075
uniprot id: A0A1B2I864
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

1197717:BED41 RS14595
gene id: 1197717:BED41_RS14595
uniprot id: A0A1B2I8D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1197717:BED41 RS15215
gene id: 1197717:BED41_RS15215
uniprot id: A0A1B2I7Q9
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1197717:BED41 RS12755
gene id: 1197717:BED41_RS12755
uniprot id: A0A1B2I7C7
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS00860
gene id: 1197717:BED41_RS00860
uniprot id: A0A1B2I1C7
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

1197717:BED41 RS13830
gene id: 1197717:BED41_RS13830
uniprot id: A0A1B2I801
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1197717:BED41 RS15415
gene id: 1197717:BED41_RS15415
uniprot id: A0A1B2I8P9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1197717:BED41 RS13165
gene id: 1197717:BED41_RS13165
uniprot id: A0A1B2I7M1
names: Similarity
messages: Belongs to the HypE family.

1197717:BED41 RS13445
gene id: 1197717:BED41_RS13445
uniprot id: A0A1B2I9P0
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1197717:BED41 RS07920
gene id: 1197717:BED41_RS07920
uniprot id: A0A1B2I4V3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1197717:BED41 RS04230
gene id: 1197717:BED41_RS04230
uniprot id: A0A1B2I311
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1197717:BED41 RS02120
gene id: 1197717:BED41_RS02120
uniprot id: A0A1B2I1Y3
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1197717:BED41 RS04375
gene id: 1197717:BED41_RS04375
uniprot id: A0A1B2I340
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

1197717:BED41 RS15100
gene id: 1197717:BED41_RS15100
uniprot id: A0A1B2I8R1
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

1197717:BED41 RS06655
gene id: 1197717:BED41_RS06655
uniprot id: A0A1B2I4A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1197717:BED41 RS15345
gene id: 1197717:BED41_RS15345
uniprot id: A0A1B2I8R4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1197717:BED41 RS04240
gene id: 1197717:BED41_RS04240
uniprot id: A0A1B2I325
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1197717:BED41 RS01625
gene id: 1197717:BED41_RS01625
uniprot id: A0A1B2I1P9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1197717:BED41 RS10780
gene id: 1197717:BED41_RS10780
uniprot id: A0A1B2I6A5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS09150
gene id: 1197717:BED41_RS09150
uniprot id: A0A1B2I5H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1197717:BED41 RS05945
gene id: 1197717:BED41_RS05945
uniprot id: A0A1B2I3Z2
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

1197717:BED41 RS09395
gene id: 1197717:BED41_RS09395
uniprot id: A0A1B2I5L8
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1197717:BED41 RS04015
gene id: 1197717:BED41_RS04015
uniprot id: A0A1B2I2Y3
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1197717:BED41 RS05260
gene id: 1197717:BED41_RS05260
uniprot id: A0A1B2I3J0
names: Similarity
messages: Belongs to the pirin family.

1197717:BED41 RS01895
gene id: 1197717:BED41_RS01895
uniprot id: A0A1B2I1W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1197717:BED41 RS08065
gene id: 1197717:BED41_RS08065
uniprot id: A0A1B2I4Z3
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1197717:BED41 RS07035
gene id: 1197717:BED41_RS07035
uniprot id: A0A1B2I4E5
names: Similarity
messages: Belongs to the aspartokinase family.

1197717:BED41 RS07465
gene id: 1197717:BED41_RS07465
uniprot id: A0A1B2I4M3
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

1197717:BED41 RS09625
gene id: 1197717:BED41_RS09625
uniprot id: A0A1B2I5S2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1197717:BED41 RS10650
gene id: 1197717:BED41_RS10650
uniprot id: A0A1B2I6B2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1197717:BED41 RS06155
gene id: 1197717:BED41_RS06155
uniprot id: A0A1B2I439
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1197717:BED41 RS05610
gene id: 1197717:BED41_RS05610
uniprot id: A0A1B2I3Q0
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1197717:BED41 RS12200
gene id: 1197717:BED41_RS12200
uniprot id: A0A1B2I9L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1197717:BED41 RS04975
gene id: 1197717:BED41_RS04975
uniprot id: A0A1B2I3E5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1197717:BED41 RS05170
gene id: 1197717:BED41_RS05170
uniprot id: A0A1B2I3M2
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1197717:BED41 RS09355
gene id: 1197717:BED41_RS09355
uniprot id: A0A1B2I5K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1197717:BED41 RS07250
gene id: 1197717:BED41_RS07250
uniprot id: A0A1B2I4L3
names: Similarity
messages: Belongs to the GARS family.

1197717:BED41 RS08115
gene id: 1197717:BED41_RS08115
uniprot id: A0A1B2I527
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TraY family.
messages: Cytoplasm

1197717:BED41 RS07040
gene id: 1197717:BED41_RS07040
uniprot id: A0A1B2I4G8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS10280
gene id: 1197717:BED41_RS10280
uniprot id: A0A1B2I612
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1197717:BED41 RS05445
gene id: 1197717:BED41_RS05445
uniprot id: A0A1B2I3M3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1197717:BED41 RS00270
gene id: 1197717:BED41_RS00270
uniprot id: A0A1B2I134
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1197717:BED41 RS05105
gene id: 1197717:BED41_RS05105
uniprot id: A0A1B2I3H3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1197717:BED41 RS07745
gene id: 1197717:BED41_RS07745
uniprot id: A0A1B2I4X1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS05875
gene id: 1197717:BED41_RS05875
uniprot id: A0A1B2I3W2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1197717:BED41 RS04480
gene id: 1197717:BED41_RS04480
uniprot id: A0A1B2I362
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1197717:BED41 RS06115
gene id: 1197717:BED41_RS06115
uniprot id: A0A1B2I3Y9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

1197717:BED41 RS00275
gene id: 1197717:BED41_RS00275
uniprot id: A0A1B2I135
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1197717:BED41 RS05825
gene id: 1197717:BED41_RS05825
uniprot id: A0A1B2I3X6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1197717:BED41 RS14780
gene id: 1197717:BED41_RS14780
uniprot id: A0A1B2I8H1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1197717:BED41 RS09135
gene id: 1197717:BED41_RS09135
uniprot id: A0A1B2I5J3
names: Similarity
messages: Belongs to the TrpF family.

1197717:BED41 RS06920
gene id: 1197717:BED41_RS06920
uniprot id: A0A1B2I4E8
names: Similarity
messages: Belongs to the peptidase S16 family.

1197717:BED41 RS00690
gene id: 1197717:BED41_RS00690
uniprot id: A0A1B2I1D6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1197717:BED41 RS15155
gene id: 1197717:BED41_RS15155
uniprot id: A0A1B2I8S0
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1197717:BED41 RS07800
gene id: 1197717:BED41_RS07800
uniprot id: A0A1B2I4U1
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1197717:BED41 RS03575
gene id: 1197717:BED41_RS03575
uniprot id: A0A1B2I2P7
names: Similarity
messages: Belongs to the peptidase C40 family.

1197717:BED41 RS04925
gene id: 1197717:BED41_RS04925
uniprot id: A0A1B2I3C1
names: Similarity
messages: Belongs to the class-I fumarase family.

1197717:BED41 RS12625
gene id: 1197717:BED41_RS12625
uniprot id: A0A1B2I7B4
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS04095
gene id: 1197717:BED41_RS04095
uniprot id: A0A1B2I2Z1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1197717:BED41 RS09910
gene id: 1197717:BED41_RS09910
uniprot id: A0A1B2I9K2
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1197717:BED41 RS07305
gene id: 1197717:BED41_RS07305
uniprot id: A0A1B2I4M2
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS03885
gene id: 1197717:BED41_RS03885
uniprot id: A0A1B2I2X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1197717:BED41 RS13090
gene id: 1197717:BED41_RS13090
uniprot id: A0A1B2I7J9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1197717:BED41 RS10680
gene id: 1197717:BED41_RS10680
uniprot id: A0A1B2I691
names: Similarity
messages: Belongs to the RNA polymerase subunit omega family.

1197717:BED41 RS03260
gene id: 1197717:BED41_RS03260
uniprot id: A0A1B2I2L1
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1197717:BED41 RS15435
gene id: 1197717:BED41_RS15435
uniprot id: A0A1B2I8T8
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1197717:BED41 RS02370
gene id: 1197717:BED41_RS02370
uniprot id: A0A1B2I248
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1197717:BED41 RS01225
gene id: 1197717:BED41_RS01225
uniprot id: A0A1B2I1I8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1197717:BED41 RS06135
gene id: 1197717:BED41_RS06135
uniprot id: A0A1B2I446
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1197717:BED41 RS15375
gene id: 1197717:BED41_RS15375
uniprot id: A0A1B2I9V7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1197717:BED41 RS10930
gene id: 1197717:BED41_RS10930
uniprot id: A0A1B2I6F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1197717:BED41 RS07865
gene id: 1197717:BED41_RS07865
uniprot id: A0A1B2I4U3
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

1197717:BED41 RS02935
gene id: 1197717:BED41_RS02935
uniprot id: A0A1B2I2E6
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS00600
gene id: 1197717:BED41_RS00600
uniprot id: A0A1B2I193
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS06880
gene id: 1197717:BED41_RS06880
uniprot id: A0A1B2I4E0
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

1197717:BED41 RS13055
gene id: 1197717:BED41_RS13055
uniprot id: A0A1B2I7M4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1197717:BED41 RS07260
gene id: 1197717:BED41_RS07260
uniprot id: A0A1B2I4J8
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS02500
gene id: 1197717:BED41_RS02500
uniprot id: A0A1B2I254
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

1197717:BED41 RS13500
gene id: 1197717:BED41_RS13500
uniprot id: A0A1B2I7R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

1197717:BED41 RS11605
gene id: 1197717:BED41_RS11605
uniprot id: A0A1B2I6S2
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS07295
gene id: 1197717:BED41_RS07295
uniprot id: A0A1B2I4J3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1197717:BED41 RS11615
gene id: 1197717:BED41_RS11615
uniprot id: A0A1B2I6T8
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

1197717:BED41 RS12690
gene id: 1197717:BED41_RS12690
uniprot id: A0A1B2I7F6
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1197717:BED41 RS03150
gene id: 1197717:BED41_RS03150
uniprot id: A0A1B2I2I7
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS11235
gene id: 1197717:BED41_RS11235
uniprot id: A0A1B2I6K3
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

1197717:BED41 RS02310
gene id: 1197717:BED41_RS02310
uniprot id: A0A1B2I256
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS04750
gene id: 1197717:BED41_RS04750
uniprot id: A0A1B2I3A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1197717:BED41 RS13550
gene id: 1197717:BED41_RS13550
uniprot id: A0A1B2I7S2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1197717:BED41 RS10880
gene id: 1197717:BED41_RS10880
uniprot id: A0A1B2I6E0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1197717:BED41 RS14720
gene id: 1197717:BED41_RS14720
uniprot id: A0A1B2I8E8
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS08080
gene id: 1197717:BED41_RS08080
uniprot id: A0A1B2I4Y1
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS08530
gene id: 1197717:BED41_RS08530
uniprot id: A0A1B2I568
names: Similarity
messages: Belongs to the Skp family.

1197717:BED41 RS05830
gene id: 1197717:BED41_RS05830
uniprot id: A0A1B2I3Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1197717:BED41 RS09900
gene id: 1197717:BED41_RS09900
uniprot id: A0A1B2I5U6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1197717:BED41 RS14775
gene id: 1197717:BED41_RS14775
uniprot id: A0A1B2I8E4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1197717:BED41 RS07555
gene id: 1197717:BED41_RS07555
uniprot id: A0A1B2I4N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1197717:BED41 RS10690
gene id: 1197717:BED41_RS10690
uniprot id: A0A1B2I9P6
names: Similarity
messages: Belongs to the RemA family.

1197717:BED41 RS05215
gene id: 1197717:BED41_RS05215
uniprot id: A0A1B2I3M0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1197717:BED41 RS05950
gene id: 1197717:BED41_RS05950
uniprot id: A0A1B2I411
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS00540
gene id: 1197717:BED41_RS00540
uniprot id: A0A1B2I188
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS03270
gene id: 1197717:BED41_RS03270
uniprot id: A0A1B2I2K1
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

1197717:BED41 RS03900
gene id: 1197717:BED41_RS03900
uniprot id: A0A1B2I2W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1197717:BED41 RS11370
gene id: 1197717:BED41_RS11370
uniprot id: A0A1B2I6L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1197717:BED41 RS07290
gene id: 1197717:BED41_RS07290
uniprot id: A0A1B2I4J0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1197717:BED41 RS11700
gene id: 1197717:BED41_RS11700
uniprot id: A0A1B2I6S3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1197717:BED41 RS07845
gene id: 1197717:BED41_RS07845
uniprot id: A0A1B2I4Y5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1197717:BED41 RS11695
gene id: 1197717:BED41_RS11695
uniprot id: A0A1B2I6T5
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS08015
gene id: 1197717:BED41_RS08015
uniprot id: A0A1B2I4Y3
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS06570
gene id: 1197717:BED41_RS06570
uniprot id: A0A1B2I477
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1197717:BED41 RS06330
gene id: 1197717:BED41_RS06330
uniprot id: A0A1B2I434
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1197717:BED41 RS12585
gene id: 1197717:BED41_RS12585
uniprot id: A0A1B2I794
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1197717:BED41 RS07635
gene id: 1197717:BED41_RS07635
uniprot id: A0A1B2I4Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1197717:BED41 RS14785
gene id: 1197717:BED41_RS14785
uniprot id: A0A1B2I8G4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1197717:BED41 RS02340
gene id: 1197717:BED41_RS02340
uniprot id: A0A1B2I246
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1197717:BED41 RS06695
gene id: 1197717:BED41_RS06695
uniprot id: A0A1B2I4E2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1197717:BED41 RS09790
gene id: 1197717:BED41_RS09790
uniprot id: A0A1B2I9L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1197717:BED41 RS08320
gene id: 1197717:BED41_RS08320
uniprot id: A0A1B2I541
names: Similarity
messages: Belongs to the peptidase A8 family.

1197717:BED41 RS06460
gene id: 1197717:BED41_RS06460
uniprot id: A0A1B2I479
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1197717:BED41 RS10320
gene id: 1197717:BED41_RS10320
uniprot id: A0A1B2I650
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1197717:BED41 RS05600
gene id: 1197717:BED41_RS05600
uniprot id: A0A1B2I3R4
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1197717:BED41 RS11455
gene id: 1197717:BED41_RS11455
uniprot id: A0A1B2I6R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1197717:BED41 RS09720
gene id: 1197717:BED41_RS09720
uniprot id: A0A1B2I5S9
names: Similarity
messages: Belongs to the GSP E family.

1197717:BED41 RS15135
gene id: 1197717:BED41_RS15135
uniprot id: A0A1B2I8K6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1197717:BED41 RS11655
gene id: 1197717:BED41_RS11655
uniprot id: A0A1B2I6V0
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1197717:BED41 RS16660
gene id: 1197717:BED41_RS16660
uniprot id: A0A1B2I758
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1197717:BED41 RS10760
gene id: 1197717:BED41_RS10760
uniprot id: A0A1B2I6D6
names: Function
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.

1197717:BED41 RS14900
gene id: 1197717:BED41_RS14900
uniprot id: A0A1B2I8H7
names: Subcellular Location Annotation
messages: Membrane

1197717:BED41 RS04605
gene id: 1197717:BED41_RS04605
uniprot id: A0A1B2I369
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

1197717:BED41 RS06320
gene id: 1197717:BED41_RS06320
uniprot id: A0A1B2I425
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1197717:BED41 RS08295
gene id: 1197717:BED41_RS08295
uniprot id: A0A1B2I544
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1197717:BED41 RS01070
gene id: 1197717:BED41_RS01070
uniprot id: A0A1B2I1G0
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

1197717:BED41 RS09525
gene id: 1197717:BED41_RS09525
uniprot id: A0A1B2I5N9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1197717:BED41 RS12130
gene id: 1197717:BED41_RS12130
uniprot id: A0A1B2I733
names: Similarity
messages: Belongs to the UPF0173 family.

1197717:BED41 RS08645
gene id: 1197717:BED41_RS08645
uniprot id: A0A1B2I573
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

1197717:BED41 RS07280
gene id: 1197717:BED41_RS07280
uniprot id: A0A1B2I4K5
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1197717:BED41 RS14710
gene id: 1197717:BED41_RS14710
uniprot id: A0A1B2I8H5
names: Similarity
messages: Belongs to the universal stress protein A family.