1196094:SALWKB2 RS08405
gene id: 1196094:SALWKB2_RS08405
uniprot id: X2H6N1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1196094:SALWKB2 RS02805
gene id: 1196094:SALWKB2_RS02805
uniprot id: X2H652
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1196094:SALWKB2 RS03905
gene id: 1196094:SALWKB2_RS03905
uniprot id: X2HF30
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1196094:SALWKB2 RS06240
gene id: 1196094:SALWKB2_RS06240
uniprot id: X2HGD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

1196094:SALWKB2 RS08400
gene id: 1196094:SALWKB2_RS08400
uniprot id: X2HD07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1196094:SALWKB2 RS00190
gene id: 1196094:SALWKB2_RS00190
uniprot id: X2HCV1
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1196094:SALWKB2 RS02095
gene id: 1196094:SALWKB2_RS02095
uniprot id: X2H338
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1196094:SALWKB2 RS01760
gene id: 1196094:SALWKB2_RS01760
uniprot id: X2H972
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1196094:SALWKB2 RS12345
gene id: 1196094:SALWKB2_RS12345
uniprot id: X2H7Q5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1196094:SALWKB2 RS11365
gene id: 1196094:SALWKB2_RS11365
uniprot id: X2HEW9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1196094:SALWKB2 RS01440
gene id: 1196094:SALWKB2_RS01440
uniprot id: X2H939
names: Similarity
messages: Belongs to the NadC/ModD family.

1196094:SALWKB2 RS03945
gene id: 1196094:SALWKB2_RS03945
uniprot id: X2H6X9
names: Similarity
messages: Belongs to the glutamine synthetase family.

1196094:SALWKB2 RS04540
gene id: 1196094:SALWKB2_RS04540
uniprot id: X2HB20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

1196094:SALWKB2 RS08760
gene id: 1196094:SALWKB2_RS08760
uniprot id: X2HHZ3
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1196094:SALWKB2 RS05880
gene id: 1196094:SALWKB2_RS05880
uniprot id: X2H564
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1196094:SALWKB2 RS09130
gene id: 1196094:SALWKB2_RS09130
uniprot id: X2HI35
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

1196094:SALWKB2 RS03040
gene id: 1196094:SALWKB2_RS03040
uniprot id: X2H9W6
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1196094:SALWKB2 RS01385
gene id: 1196094:SALWKB2_RS01385
uniprot id: X2H2T1
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Belongs to the group II decarboxylase family.

1196094:SALWKB2 RS08510
gene id: 1196094:SALWKB2_RS08510
uniprot id: X2H9M7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1196094:SALWKB2 RS05765
gene id: 1196094:SALWKB2_RS05765
uniprot id: X2H7Z4
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1196094:SALWKB2 RS01055
gene id: 1196094:SALWKB2_RS01055
uniprot id: X2H568
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

1196094:SALWKB2 RS09855
gene id: 1196094:SALWKB2_RS09855
uniprot id: X2HAB7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1196094:SALWKB2 RS10680
gene id: 1196094:SALWKB2_RS10680
uniprot id: X2HIW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1196094:SALWKB2 RS06020
gene id: 1196094:SALWKB2_RS06020
uniprot id: X2HBZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1196094:SALWKB2 RS04370
gene id: 1196094:SALWKB2_RS04370
uniprot id: X2H758
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1196094:SALWKB2 RS09215
gene id: 1196094:SALWKB2_RS09215
uniprot id: X2HDG8
names: Similarity
messages: Belongs to the YkuD family.

1196094:SALWKB2 RS11050
gene id: 1196094:SALWKB2_RS11050
uniprot id: X2H857
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1196094:SALWKB2 RS04380
gene id: 1196094:SALWKB2_RS04380
uniprot id: X2HAZ2
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

1196094:SALWKB2 RS07475
gene id: 1196094:SALWKB2_RS07475
uniprot id: X2HCD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1196094:SALWKB2 RS10435
gene id: 1196094:SALWKB2_RS10435
uniprot id: X2HAM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1196094:SALWKB2 RS07365
gene id: 1196094:SALWKB2_RS07365
uniprot id: X2HGZ0
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

1196094:SALWKB2 RS10270
gene id: 1196094:SALWKB2_RS10270
uniprot id: X2HIM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

1196094:SALWKB2 RS06755
gene id: 1196094:SALWKB2_RS06755
uniprot id: X2HCE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Membrane

1196094:SALWKB2 RS00380
gene id: 1196094:SALWKB2_RS00380
uniprot id: X2HCZ3
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1196094:SALWKB2 RS04035
gene id: 1196094:SALWKB2_RS04035
uniprot id: X2H6Z3
names: Similarity
messages: Belongs to the threonine synthase family.

1196094:SALWKB2 RS01390
gene id: 1196094:SALWKB2_RS01390
uniprot id: X2H5G0
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1196094:SALWKB2 RS09160
gene id: 1196094:SALWKB2_RS09160
uniprot id: X2HDP3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1196094:SALWKB2 RS02280
gene id: 1196094:SALWKB2_RS02280
uniprot id: X2H9I0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1196094:SALWKB2 RS06000
gene id: 1196094:SALWKB2_RS06000
uniprot id: X2HBK9
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1196094:SALWKB2 RS10745
gene id: 1196094:SALWKB2_RS10745
uniprot id: X2HIX8
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1196094:SALWKB2 RS04010
gene id: 1196094:SALWKB2_RS04010
uniprot id: X2H6Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1196094:SALWKB2 RS07395
gene id: 1196094:SALWKB2_RS07395
uniprot id: X2HCN9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1196094:SALWKB2 RS10930
gene id: 1196094:SALWKB2_RS10930
uniprot id: X2HEJ2
names: Similarity
messages: Belongs to the P(II) protein family.

1196094:SALWKB2 RS02835
gene id: 1196094:SALWKB2_RS02835
uniprot id: X2HEC6
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

1196094:SALWKB2 RS07340
gene id: 1196094:SALWKB2_RS07340
uniprot id: X2HGY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1196094:SALWKB2 RS06765
gene id: 1196094:SALWKB2_RS06765
uniprot id: X2H5Q9
names: Caution
names: Function
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1196094:SALWKB2 RS07355
gene id: 1196094:SALWKB2_RS07355
uniprot id: X2H609
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS04655
gene id: 1196094:SALWKB2_RS04655
uniprot id: X2HFF4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1196094:SALWKB2 RS10465
gene id: 1196094:SALWKB2_RS10465
uniprot id: X2HIS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1196094:SALWKB2 RS01085
gene id: 1196094:SALWKB2_RS01085
uniprot id: X2H8W8
names: Similarity
messages: Belongs to the BolA/IbaG family.

1196094:SALWKB2 RS04415
gene id: 1196094:SALWKB2_RS04415
uniprot id: X2H4E8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1196094:SALWKB2 RS08470
gene id: 1196094:SALWKB2_RS08470
uniprot id: X2HDA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1196094:SALWKB2 RS01315
gene id: 1196094:SALWKB2_RS01315
uniprot id: X2H2R7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1196094:SALWKB2 RS04270
gene id: 1196094:SALWKB2_RS04270
uniprot id: X2HAN4
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

1196094:SALWKB2 RS04195
gene id: 1196094:SALWKB2_RS04195
uniprot id: X2HAV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

1196094:SALWKB2 RS08665
gene id: 1196094:SALWKB2_RS08665
uniprot id: X2HHV1
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS08270
gene id: 1196094:SALWKB2_RS08270
uniprot id: X2HHI6
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1196094:SALWKB2 RS03425
gene id: 1196094:SALWKB2_RS03425
uniprot id: X2HAD9
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1196094:SALWKB2 RS04165
gene id: 1196094:SALWKB2_RS04165
uniprot id: X2HF74
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1196094:SALWKB2 RS10365
gene id: 1196094:SALWKB2_RS10365
uniprot id: X2HAK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1196094:SALWKB2 RS06875
gene id: 1196094:SALWKB2_RS06875
uniprot id: X2HGR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1196094:SALWKB2 RS06515
gene id: 1196094:SALWKB2_RS06515
uniprot id: X2H5M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1196094:SALWKB2 RS09840
gene id: 1196094:SALWKB2_RS09840
uniprot id: X2HDY9
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS07015
gene id: 1196094:SALWKB2_RS07015
uniprot id: X2HCI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

1196094:SALWKB2 RS06575
gene id: 1196094:SALWKB2_RS06575
uniprot id: X2HCC0
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

1196094:SALWKB2 RS01220
gene id: 1196094:SALWKB2_RS01220
uniprot id: X2H8Z5
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1196094:SALWKB2 RS03245
gene id: 1196094:SALWKB2_RS03245
uniprot id: X2HA97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1196094:SALWKB2 RS05265
gene id: 1196094:SALWKB2_RS05265
uniprot id: X2H4S7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1196094:SALWKB2 RS01815
gene id: 1196094:SALWKB2_RS01815
uniprot id: X2H2Y6
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

1196094:SALWKB2 RS04240
gene id: 1196094:SALWKB2_RS04240
uniprot id: X2HAW6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

1196094:SALWKB2 RS09040
gene id: 1196094:SALWKB2_RS09040
uniprot id: X2HI24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

1196094:SALWKB2 RS04190
gene id: 1196094:SALWKB2_RS04190
uniprot id: X2HF78
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1196094:SALWKB2 RS01100
gene id: 1196094:SALWKB2_RS01100
uniprot id: X2HDF5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

1196094:SALWKB2 RS01915
gene id: 1196094:SALWKB2_RS01915
uniprot id: X2H301
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS07570
gene id: 1196094:SALWKB2_RS07570
uniprot id: X2HH32
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1196094:SALWKB2 RS03435
gene id: 1196094:SALWKB2_RS03435
uniprot id: X2H3T4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1196094:SALWKB2 RS12395
gene id: 1196094:SALWKB2_RS12395
uniprot id: X2HDN9
names: Subcellular Location Annotation
messages: target cell cytoplasm

1196094:SALWKB2 RS00985
gene id: 1196094:SALWKB2_RS00985
uniprot id: X2H8U2
names: Function
names: Similarity
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.

1196094:SALWKB2 RS06590
gene id: 1196094:SALWKB2_RS06590
uniprot id: X2H8K1
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

1196094:SALWKB2 RS04885
gene id: 1196094:SALWKB2_RS04885
uniprot id: X2H4L7
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

1196094:SALWKB2 RS09925
gene id: 1196094:SALWKB2_RS09925
uniprot id: X2HAD0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1196094:SALWKB2 RS05495
gene id: 1196094:SALWKB2_RS05495
uniprot id: X2H7R0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1196094:SALWKB2 RS03555
gene id: 1196094:SALWKB2_RS03555
uniprot id: X2HAA3
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

1196094:SALWKB2 RS03795
gene id: 1196094:SALWKB2_RS03795
uniprot id: X2HF12
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

1196094:SALWKB2 RS03700
gene id: 1196094:SALWKB2_RS03700
uniprot id: X2HEW6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1196094:SALWKB2 RS04790
gene id: 1196094:SALWKB2_RS04790
uniprot id: X2H4K1
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

1196094:SALWKB2 RS01345
gene id: 1196094:SALWKB2_RS01345
uniprot id: X2H5F2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1196094:SALWKB2 RS01240
gene id: 1196094:SALWKB2_RS01240
uniprot id: X2H961
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1196094:SALWKB2 RS01350
gene id: 1196094:SALWKB2_RS01350
uniprot id: X2HDN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1196094:SALWKB2 RS01570
gene id: 1196094:SALWKB2_RS01570
uniprot id: X2HDQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1196094:SALWKB2 RS01320
gene id: 1196094:SALWKB2_RS01320
uniprot id: X2H5E8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1196094:SALWKB2 RS00825
gene id: 1196094:SALWKB2_RS00825
uniprot id: X2HD91
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.

1196094:SALWKB2 RS08490
gene id: 1196094:SALWKB2_RS08490
uniprot id: X2HHP9
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1196094:SALWKB2 RS09245
gene id: 1196094:SALWKB2_RS09245
uniprot id: X2HI55
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1196094:SALWKB2 RS05320
gene id: 1196094:SALWKB2_RS05320
uniprot id: X2H7M9
names: Similarity
messages: Belongs to the peptidase S41A family.

1196094:SALWKB2 RS03120
gene id: 1196094:SALWKB2_RS03120
uniprot id: X2H6B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1196094:SALWKB2 RS08990
gene id: 1196094:SALWKB2_RS08990
uniprot id: X2HDL8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1196094:SALWKB2 RS06955
gene id: 1196094:SALWKB2_RS06955
uniprot id: X2HCH7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1196094:SALWKB2 RS05870
gene id: 1196094:SALWKB2_RS05870
uniprot id: X2HBV0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1196094:SALWKB2 RS02860
gene id: 1196094:SALWKB2_RS02860
uniprot id: X2HED2
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS00195
gene id: 1196094:SALWKB2_RS00195
uniprot id: X2H8K8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1196094:SALWKB2 RS09000
gene id: 1196094:SALWKB2_RS09000
uniprot id: X2H725
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1196094:SALWKB2 RS02285
gene id: 1196094:SALWKB2_RS02285
uniprot id: X2H372
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1196094:SALWKB2 RS02760
gene id: 1196094:SALWKB2_RS02760
uniprot id: X2HEB0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1196094:SALWKB2 RS04020
gene id: 1196094:SALWKB2_RS04020
uniprot id: X2HAS9
names: Similarity
messages: Belongs to the aldose epimerase family.

1196094:SALWKB2 RS05365
gene id: 1196094:SALWKB2_RS05365
uniprot id: X2HB67
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1196094:SALWKB2 RS06485
gene id: 1196094:SALWKB2_RS06485
uniprot id: X2HBW5
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

1196094:SALWKB2 RS02905
gene id: 1196094:SALWKB2_RS02905
uniprot id: X2H671
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS00335
gene id: 1196094:SALWKB2_RS00335
uniprot id: X2H8N6
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

1196094:SALWKB2 RS04690
gene id: 1196094:SALWKB2_RS04690
uniprot id: X2H4I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1196094:SALWKB2 RS03960
gene id: 1196094:SALWKB2_RS03960
uniprot id: X2H472
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1196094:SALWKB2 RS09185
gene id: 1196094:SALWKB2_RS09185
uniprot id: X2HDP9
names: Similarity
messages: Belongs to the BolA/IbaG family.

1196094:SALWKB2 RS11480
gene id: 1196094:SALWKB2_RS11480
uniprot id: X2HJK2
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1196094:SALWKB2 RS00220
gene id: 1196094:SALWKB2_RS00220
uniprot id: X2H8L4
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1196094:SALWKB2 RS11445
gene id: 1196094:SALWKB2_RS11445
uniprot id: X2HEX8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1196094:SALWKB2 RS00140
gene id: 1196094:SALWKB2_RS00140
uniprot id: X2H8J8
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1196094:SALWKB2 RS07595
gene id: 1196094:SALWKB2_RS07595
uniprot id: X2HH36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1196094:SALWKB2 RS02920
gene id: 1196094:SALWKB2_RS02920
uniprot id: X2H9T8
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS08825
gene id: 1196094:SALWKB2_RS08825
uniprot id: X2HDJ9
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1196094:SALWKB2 RS08595
gene id: 1196094:SALWKB2_RS08595
uniprot id: X2HDE0
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1196094:SALWKB2 RS06460
gene id: 1196094:SALWKB2_RS06460
uniprot id: X2HBW2
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1196094:SALWKB2 RS01380
gene id: 1196094:SALWKB2_RS01380
uniprot id: X2H930
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1196094:SALWKB2 RS01205
gene id: 1196094:SALWKB2_RS01205
uniprot id: X2H5A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1196094:SALWKB2 RS08740
gene id: 1196094:SALWKB2_RS08740
uniprot id: X2HHX0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1196094:SALWKB2 RS08955
gene id: 1196094:SALWKB2_RS08955
uniprot id: X2H9Y6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1196094:SALWKB2 RS02775
gene id: 1196094:SALWKB2_RS02775
uniprot id: X2H3E8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1196094:SALWKB2 RS00060
gene id: 1196094:SALWKB2_RS00060
uniprot id: X2H4M7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1196094:SALWKB2 RS08360
gene id: 1196094:SALWKB2_RS08360
uniprot id: X2H9I6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

1196094:SALWKB2 RS00095
gene id: 1196094:SALWKB2_RS00095
uniprot id: X2H8C1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1196094:SALWKB2 RS03235
gene id: 1196094:SALWKB2_RS03235
uniprot id: X2H6F2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1196094:SALWKB2 RS04125
gene id: 1196094:SALWKB2_RS04125
uniprot id: X2HAL5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1196094:SALWKB2 RS10015
gene id: 1196094:SALWKB2_RS10015
uniprot id: X2HDV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1196094:SALWKB2 RS00785
gene id: 1196094:SALWKB2_RS00785
uniprot id: X2H8Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1196094:SALWKB2 RS07505
gene id: 1196094:SALWKB2_RS07505
uniprot id: X2H634
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1196094:SALWKB2 RS06845
gene id: 1196094:SALWKB2_RS06845
uniprot id: X2H8N7
names: Similarity
messages: Belongs to the aspartokinase family.

1196094:SALWKB2 RS01165
gene id: 1196094:SALWKB2_RS01165
uniprot id: X2H2L6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1196094:SALWKB2 RS03885
gene id: 1196094:SALWKB2_RS03885
uniprot id: X2HAQ8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1196094:SALWKB2 RS07220
gene id: 1196094:SALWKB2_RS07220
uniprot id: X2HCL3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1196094:SALWKB2 RS08005
gene id: 1196094:SALWKB2_RS08005
uniprot id: X2H984
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1196094:SALWKB2 RS01115
gene id: 1196094:SALWKB2_RS01115
uniprot id: X2H2K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

1196094:SALWKB2 RS08350
gene id: 1196094:SALWKB2_RS08350
uniprot id: X2HCZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane

1196094:SALWKB2 RS05960
gene id: 1196094:SALWKB2_RS05960
uniprot id: X2H853
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.

1196094:SALWKB2 RS01455
gene id: 1196094:SALWKB2_RS01455
uniprot id: X2HDP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1196094:SALWKB2 RS00360
gene id: 1196094:SALWKB2_RS00360
uniprot id: X2H8P1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1196094:SALWKB2 RS11355
gene id: 1196094:SALWKB2_RS11355
uniprot id: X2HBC5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1196094:SALWKB2 RS01685
gene id: 1196094:SALWKB2_RS01685
uniprot id: X2H968
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

1196094:SALWKB2 RS06850
gene id: 1196094:SALWKB2_RS06850
uniprot id: X2HGQ7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

1196094:SALWKB2 RS03180
gene id: 1196094:SALWKB2_RS03180
uniprot id: X2HA82
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS05185
gene id: 1196094:SALWKB2_RS05185
uniprot id: X2HB35
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS08080
gene id: 1196094:SALWKB2_RS08080
uniprot id: X2H9A3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

1196094:SALWKB2 RS10490
gene id: 1196094:SALWKB2_RS10490
uniprot id: X2HIS4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1196094:SALWKB2 RS01120
gene id: 1196094:SALWKB2_RS01120
uniprot id: X2H587
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

1196094:SALWKB2 RS09960
gene id: 1196094:SALWKB2_RS09960
uniprot id: X2HDT5
names: Similarity
messages: Belongs to the YjdM family.

1196094:SALWKB2 RS01895
gene id: 1196094:SALWKB2_RS01895
uniprot id: X2H5N3
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1196094:SALWKB2 RS10875
gene id: 1196094:SALWKB2_RS10875
uniprot id: X2HEK1
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1196094:SALWKB2 RS02820
gene id: 1196094:SALWKB2_RS02820
uniprot id: X2H9S3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

1196094:SALWKB2 RS03990
gene id: 1196094:SALWKB2_RS03990
uniprot id: X2HF45
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1196094:SALWKB2 RS07760
gene id: 1196094:SALWKB2_RS07760
uniprot id: X2HCW8
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS10450
gene id: 1196094:SALWKB2_RS10450
uniprot id: X2HE61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1196094:SALWKB2 RS00965
gene id: 1196094:SALWKB2_RS00965
uniprot id: X2H2G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1196094:SALWKB2 RS07910
gene id: 1196094:SALWKB2_RS07910
uniprot id: X2H6A1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1196094:SALWKB2 RS06560
gene id: 1196094:SALWKB2_RS06560
uniprot id: X2H5M8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1196094:SALWKB2 RS10640
gene id: 1196094:SALWKB2_RS10640
uniprot id: X2HAT4
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS11160
gene id: 1196094:SALWKB2_RS11160
uniprot id: X2HJB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein.
messages: Oligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.

1196094:SALWKB2 RS01810
gene id: 1196094:SALWKB2_RS01810
uniprot id: X2H980
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1196094:SALWKB2 RS01195
gene id: 1196094:SALWKB2_RS01195
uniprot id: X2H950
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

1196094:SALWKB2 RS01785
gene id: 1196094:SALWKB2_RS01785
uniprot id: X2H976
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1196094:SALWKB2 RS05385
gene id: 1196094:SALWKB2_RS05385
uniprot id: X2HBI0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1196094:SALWKB2 RS04155
gene id: 1196094:SALWKB2_RS04155
uniprot id: X2H4A5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1196094:SALWKB2 RS01555
gene id: 1196094:SALWKB2_RS01555
uniprot id: X2H951
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1196094:SALWKB2 RS08315
gene id: 1196094:SALWKB2_RS08315
uniprot id: X2HHK0
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1196094:SALWKB2 RS10755
gene id: 1196094:SALWKB2_RS10755
uniprot id: X2HEE3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1196094:SALWKB2 RS00365
gene id: 1196094:SALWKB2_RS00365
uniprot id: X2H8G8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1196094:SALWKB2 RS08195
gene id: 1196094:SALWKB2_RS08195
uniprot id: X2HHG8
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1196094:SALWKB2 RS08650
gene id: 1196094:SALWKB2_RS08650
uniprot id: X2HD63
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1196094:SALWKB2 RS00430
gene id: 1196094:SALWKB2_RS00430
uniprot id: X2HD08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1196094:SALWKB2 RS00840
gene id: 1196094:SALWKB2_RS00840
uniprot id: X2H2E0
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1196094:SALWKB2 RS07470
gene id: 1196094:SALWKB2_RS07470
uniprot id: X2HCQ4
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1196094:SALWKB2 RS06280
gene id: 1196094:SALWKB2_RS06280
uniprot id: X2HC66
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.

1196094:SALWKB2 RS01515
gene id: 1196094:SALWKB2_RS01515
uniprot id: X2H2U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1196094:SALWKB2 RS10915
gene id: 1196094:SALWKB2_RS10915
uniprot id: X2HB06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1196094:SALWKB2 RS04860
gene id: 1196094:SALWKB2_RS04860
uniprot id: X2H4L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1196094:SALWKB2 RS01300
gene id: 1196094:SALWKB2_RS01300
uniprot id: X2HDM2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1196094:SALWKB2 RS03685
gene id: 1196094:SALWKB2_RS03685
uniprot id: X2HAK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Set transporter family.
messages: Membrane

1196094:SALWKB2 RS09110
gene id: 1196094:SALWKB2_RS09110
uniprot id: X2HI32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

1196094:SALWKB2 RS10670
gene id: 1196094:SALWKB2_RS10670
uniprot id: X2H7V5
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
messages: Homodimer.

1196094:SALWKB2 RS03255
gene id: 1196094:SALWKB2_RS03255
uniprot id: X2H3N8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1196094:SALWKB2 RS08565
gene id: 1196094:SALWKB2_RS08565
uniprot id: X2HHS3
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS01780
gene id: 1196094:SALWKB2_RS01780
uniprot id: X2H9F9
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1196094:SALWKB2 RS07625
gene id: 1196094:SALWKB2_RS07625
uniprot id: X2H655
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1196094:SALWKB2 RS03790
gene id: 1196094:SALWKB2_RS03790
uniprot id: X2H6V9
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1196094:SALWKB2 RS09135
gene id: 1196094:SALWKB2_RS09135
uniprot id: X2HDP0
names: Similarity
messages: Belongs to the UPF0237 family.

1196094:SALWKB2 RS08645
gene id: 1196094:SALWKB2_RS08645
uniprot id: X2HDF3
names: Similarity
messages: Belongs to the UPF0053 family.

1196094:SALWKB2 RS08820
gene id: 1196094:SALWKB2_RS08820
uniprot id: X2HI02
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1196094:SALWKB2 RS10600
gene id: 1196094:SALWKB2_RS10600
uniprot id: X2HEE4
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS09125
gene id: 1196094:SALWKB2_RS09125
uniprot id: X2H744
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1196094:SALWKB2 RS03065
gene id: 1196094:SALWKB2_RS03065
uniprot id: X2H9X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1196094:SALWKB2 RS10765
gene id: 1196094:SALWKB2_RS10765
uniprot id: X2HAX0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1196094:SALWKB2 RS01870
gene id: 1196094:SALWKB2_RS01870
uniprot id: X2H5M7
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Belongs to the trans-sulfuration enzymes family.

1196094:SALWKB2 RS03690
gene id: 1196094:SALWKB2_RS03690
uniprot id: X2HAD6
names: Similarity
messages: Belongs to the asparaginase 1 family.

1196094:SALWKB2 RS06455
gene id: 1196094:SALWKB2_RS06455
uniprot id: X2HCA0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

1196094:SALWKB2 RS05360
gene id: 1196094:SALWKB2_RS05360
uniprot id: X2HBH5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1196094:SALWKB2 RS09870
gene id: 1196094:SALWKB2_RS09870
uniprot id: X2HDR5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

1196094:SALWKB2 RS01310
gene id: 1196094:SALWKB2_RS01310
uniprot id: X2H921
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1196094:SALWKB2 RS07980
gene id: 1196094:SALWKB2_RS07980
uniprot id: X2H979
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1196094:SALWKB2 RS02945
gene id: 1196094:SALWKB2_RS02945
uniprot id: X2H9U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

1196094:SALWKB2 RS10770
gene id: 1196094:SALWKB2_RS10770
uniprot id: X2HIY2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1196094:SALWKB2 RS03640
gene id: 1196094:SALWKB2_RS03640
uniprot id: X2H6Q2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1196094:SALWKB2 RS04025
gene id: 1196094:SALWKB2_RS04025
uniprot id: X2HAK1
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

1196094:SALWKB2 RS08600
gene id: 1196094:SALWKB2_RS08600
uniprot id: X2HD51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1196094:SALWKB2 RS06005
gene id: 1196094:SALWKB2_RS06005
uniprot id: X2H598
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1196094:SALWKB2 RS09590
gene id: 1196094:SALWKB2_RS09590
uniprot id: X2H7B7
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1196094:SALWKB2 RS11315
gene id: 1196094:SALWKB2_RS11315
uniprot id: X2HEW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1196094:SALWKB2 RS06815
gene id: 1196094:SALWKB2_RS06815
uniprot id: X2H5R8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1196094:SALWKB2 RS06440
gene id: 1196094:SALWKB2_RS06440
uniprot id: X2HBV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1196094:SALWKB2 RS10675
gene id: 1196094:SALWKB2_RS10675
uniprot id: X2HAU3
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1196094:SALWKB2 RS05345
gene id: 1196094:SALWKB2_RS05345
uniprot id: X2H7N3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1196094:SALWKB2 RS00010
gene id: 1196094:SALWKB2_RS00010
uniprot id: X2HCQ7
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1196094:SALWKB2 RS03515
gene id: 1196094:SALWKB2_RS03515
uniprot id: X2HES1
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1196094:SALWKB2 RS08775
gene id: 1196094:SALWKB2_RS08775
uniprot id: X2H6Z1
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1196094:SALWKB2 RS10955
gene id: 1196094:SALWKB2_RS10955
uniprot id: X2HEJ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1196094:SALWKB2 RS04930
gene id: 1196094:SALWKB2_RS04930
uniprot id: X2HAZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1196094:SALWKB2 RS03985
gene id: 1196094:SALWKB2_RS03985
uniprot id: X2H6Y5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1196094:SALWKB2 RS10010
gene id: 1196094:SALWKB2_RS10010
uniprot id: X2HE24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1196094:SALWKB2 RS03095
gene id: 1196094:SALWKB2_RS03095
uniprot id: X2H3K4
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1196094:SALWKB2 RS05625
gene id: 1196094:SALWKB2_RS05625
uniprot id: X2H7U8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1196094:SALWKB2 RS08705
gene id: 1196094:SALWKB2_RS08705
uniprot id: X2H6V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1196094:SALWKB2 RS02755
gene id: 1196094:SALWKB2_RS02755
uniprot id: X2H644
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

1196094:SALWKB2 RS06015
gene id: 1196094:SALWKB2_RS06015
uniprot id: X2HG75
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS00030
gene id: 1196094:SALWKB2_RS00030
uniprot id: X2H4M2
names: Similarity
messages: Belongs to the GARS family.

1196094:SALWKB2 RS05170
gene id: 1196094:SALWKB2_RS05170
uniprot id: X2H7K4
names: Similarity
messages: Belongs to the TrpC family.

1196094:SALWKB2 RS11205
gene id: 1196094:SALWKB2_RS11205
uniprot id: X2HET2
names: Similarity
messages: Belongs to the stealth family.

1196094:SALWKB2 RS10785
gene id: 1196094:SALWKB2_RS10785
uniprot id: X2H7Y2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1196094:SALWKB2 RS09630
gene id: 1196094:SALWKB2_RS09630
uniprot id: X2HDM4
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

1196094:SALWKB2 RS00975
gene id: 1196094:SALWKB2_RS00975
uniprot id: X2HDB9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1196094:SALWKB2 RS07715
gene id: 1196094:SALWKB2_RS07715
uniprot id: X2HCV8
names: Similarity
messages: Belongs to the YciI family.

1196094:SALWKB2 RS06150
gene id: 1196094:SALWKB2_RS06150
uniprot id: X2HBP7
names: Similarity
messages: Belongs to the YfgM family.

1196094:SALWKB2 RS05335
gene id: 1196094:SALWKB2_RS05335
uniprot id: X2HB62
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1196094:SALWKB2 RS03140
gene id: 1196094:SALWKB2_RS03140
uniprot id: X2H3L4
names: Similarity
messages: Belongs to the ModE family.

1196094:SALWKB2 RS02105
gene id: 1196094:SALWKB2_RS02105
uniprot id: X2HDZ8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1196094:SALWKB2 RS06175
gene id: 1196094:SALWKB2_RS06175
uniprot id: X2HBQ2
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

1196094:SALWKB2 RS08995
gene id: 1196094:SALWKB2_RS08995
uniprot id: X2HDD8
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

1196094:SALWKB2 RS07445
gene id: 1196094:SALWKB2_RS07445
uniprot id: X2HCP9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1196094:SALWKB2 RS01260
gene id: 1196094:SALWKB2_RS01260
uniprot id: X2H977
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1196094:SALWKB2 RS03090
gene id: 1196094:SALWKB2_RS03090
uniprot id: X2H9X9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1196094:SALWKB2 RS05025
gene id: 1196094:SALWKB2_RS05025
uniprot id: X2HBA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1196094:SALWKB2 RS02345
gene id: 1196094:SALWKB2_RS02345
uniprot id: X2H9R6
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1196094:SALWKB2 RS03215
gene id: 1196094:SALWKB2_RS03215
uniprot id: X2H6E5
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1196094:SALWKB2 RS01355
gene id: 1196094:SALWKB2_RS01355
uniprot id: X2H998
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1196094:SALWKB2 RS04015
gene id: 1196094:SALWKB2_RS04015
uniprot id: X2HF48
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

1196094:SALWKB2 RS06610
gene id: 1196094:SALWKB2_RS06610
uniprot id: X2H8K4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

1196094:SALWKB2 RS11320
gene id: 1196094:SALWKB2_RS11320
uniprot id: X2HEU8
names: Similarity
messages: Belongs to the peptidase S51 family.

1196094:SALWKB2 RS04385
gene id: 1196094:SALWKB2_RS04385
uniprot id: X2HAQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1196094:SALWKB2 RS07640
gene id: 1196094:SALWKB2_RS07640
uniprot id: X2HCU2
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS08555
gene id: 1196094:SALWKB2_RS08555
uniprot id: X2H9N8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1196094:SALWKB2 RS01435
gene id: 1196094:SALWKB2_RS01435
uniprot id: X2H9B0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1196094:SALWKB2 RS11255
gene id: 1196094:SALWKB2_RS11255
uniprot id: X2HBB1
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1196094:SALWKB2 RS03980
gene id: 1196094:SALWKB2_RS03980
uniprot id: X2H475
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1196094:SALWKB2 RS04360
gene id: 1196094:SALWKB2_RS04360
uniprot id: X2HAQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1196094:SALWKB2 RS04280
gene id: 1196094:SALWKB2_RS04280
uniprot id: X2H742
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1196094:SALWKB2 RS03610
gene id: 1196094:SALWKB2_RS03610
uniprot id: X2H3X8
names: Similarity
messages: Belongs to the peptidase M24B family.

1196094:SALWKB2 RS00115
gene id: 1196094:SALWKB2_RS00115
uniprot id: X2H8J2
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1196094:SALWKB2 RS00955
gene id: 1196094:SALWKB2_RS00955
uniprot id: X2H8Z8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1196094:SALWKB2 RS08480
gene id: 1196094:SALWKB2_RS08480
uniprot id: X2H6Q1
names: Subcellular Location Annotation
messages: Mitochondrion

1196094:SALWKB2 RS07245
gene id: 1196094:SALWKB2_RS07245
uniprot id: X2HCL7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1196094:SALWKB2 RS06570
gene id: 1196094:SALWKB2_RS06570
uniprot id: X2HGK8
names: Similarity
messages: Belongs to the citrate synthase family.

1196094:SALWKB2 RS03080
gene id: 1196094:SALWKB2_RS03080
uniprot id: X2HEH6
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1196094:SALWKB2 RS05455
gene id: 1196094:SALWKB2_RS05455
uniprot id: X2HB82
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1196094:SALWKB2 RS04535
gene id: 1196094:SALWKB2_RS04535
uniprot id: X2HFD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Membrane

1196094:SALWKB2 RS10380
gene id: 1196094:SALWKB2_RS10380
uniprot id: X2HE38
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 104 family.
messages: Protein-arginine rhamnosyltransferase that catalyzes the transfer of a single rhamnose to elongation factor P (EF-P) on 'Lys-32', a modification required for EF-P-dependent rescue of polyproline stalled ribosomes.

1196094:SALWKB2 RS09850
gene id: 1196094:SALWKB2_RS09850
uniprot id: X2H7F1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1196094:SALWKB2 RS10830
gene id: 1196094:SALWKB2_RS10830
uniprot id: X2HEG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1196094:SALWKB2 RS03470
gene id: 1196094:SALWKB2_RS03470
uniprot id: X2HAF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1196094:SALWKB2 RS01010
gene id: 1196094:SALWKB2_RS01010
uniprot id: X2H553
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1196094:SALWKB2 RS00120
gene id: 1196094:SALWKB2_RS00120
uniprot id: X2H8C7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

1196094:SALWKB2 RS07250
gene id: 1196094:SALWKB2_RS07250
uniprot id: X2HC85
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1196094:SALWKB2 RS11155
gene id: 1196094:SALWKB2_RS11155
uniprot id: X2HB72
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Oligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.

1196094:SALWKB2 RS10220
gene id: 1196094:SALWKB2_RS10220
uniprot id: X2H7L0
names: Similarity
messages: Belongs to the isochorismate synthase family.

1196094:SALWKB2 RS06185
gene id: 1196094:SALWKB2_RS06185
uniprot id: X2H8B5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1196094:SALWKB2 RS04000
gene id: 1196094:SALWKB2_RS04000
uniprot id: X2HAJ8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1196094:SALWKB2 RS02275
gene id: 1196094:SALWKB2_RS02275
uniprot id: X2H9Q2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1196094:SALWKB2 RS04310
gene id: 1196094:SALWKB2_RS04310
uniprot id: X2HF98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1196094:SALWKB2 RS07665
gene id: 1196094:SALWKB2_RS07665
uniprot id: X2HCU7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1196094:SALWKB2 RS00065
gene id: 1196094:SALWKB2_RS00065
uniprot id: X2HCS1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1196094:SALWKB2 RS07525
gene id: 1196094:SALWKB2_RS07525
uniprot id: X2HCR5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1196094:SALWKB2 RS07260
gene id: 1196094:SALWKB2_RS07260
uniprot id: X2H8V9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1196094:SALWKB2 RS11185
gene id: 1196094:SALWKB2_RS11185
uniprot id: X2H8B2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1196094:SALWKB2 RS00960
gene id: 1196094:SALWKB2_RS00960
uniprot id: X2H8T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

1196094:SALWKB2 RS07310
gene id: 1196094:SALWKB2_RS07310
uniprot id: X2H8W2
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1196094:SALWKB2 RS06785
gene id: 1196094:SALWKB2_RS06785
uniprot id: X2HC08
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1196094:SALWKB2 RS03285
gene id: 1196094:SALWKB2_RS03285
uniprot id: X2H6G7
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS03930
gene id: 1196094:SALWKB2_RS03930
uniprot id: X2HAR5
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1196094:SALWKB2 RS08150
gene id: 1196094:SALWKB2_RS08150
uniprot id: X2H9C3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1196094:SALWKB2 RS05975
gene id: 1196094:SALWKB2_RS05975
uniprot id: X2HBK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1196094:SALWKB2 RS08420
gene id: 1196094:SALWKB2_RS08420
uniprot id: X2HDA0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1196094:SALWKB2 RS10210
gene id: 1196094:SALWKB2_RS10210
uniprot id: X2HE55
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS06160
gene id: 1196094:SALWKB2_RS06160
uniprot id: X2H8A7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1196094:SALWKB2 RS10865
gene id: 1196094:SALWKB2_RS10865
uniprot id: X2HAZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1196094:SALWKB2 RS01290
gene id: 1196094:SALWKB2_RS01290
uniprot id: X2H998
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1196094:SALWKB2 RS00345
gene id: 1196094:SALWKB2_RS00345
uniprot id: X2H233
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1196094:SALWKB2 RS00005
gene id: 1196094:SALWKB2_RS00005
uniprot id: X2H1X2
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

1196094:SALWKB2 RS04485
gene id: 1196094:SALWKB2_RS04485
uniprot id: X2HB10
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1196094:SALWKB2 RS03630
gene id: 1196094:SALWKB2_RS03630
uniprot id: X2HAC0
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1196094:SALWKB2 RS08260
gene id: 1196094:SALWKB2_RS08260
uniprot id: X2H6J6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1196094:SALWKB2 RS00255
gene id: 1196094:SALWKB2_RS00255
uniprot id: X2H220
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1196094:SALWKB2 RS07170
gene id: 1196094:SALWKB2_RS07170
uniprot id: X2HGW0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters.

1196094:SALWKB2 RS04430
gene id: 1196094:SALWKB2_RS04430
uniprot id: X2HB00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1196094:SALWKB2 RS08175
gene id: 1196094:SALWKB2_RS08175
uniprot id: X2HHG3
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.

1196094:SALWKB2 RS00160
gene id: 1196094:SALWKB2_RS00160
uniprot id: X2HCU5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1196094:SALWKB2 RS10895
gene id: 1196094:SALWKB2_RS10895
uniprot id: X2HJ22
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1196094:SALWKB2 RS08685
gene id: 1196094:SALWKB2_RS08685
uniprot id: X2H9R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1196094:SALWKB2 RS10750
gene id: 1196094:SALWKB2_RS10750
uniprot id: X2HEH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1196094:SALWKB2 RS11295
gene id: 1196094:SALWKB2_RS11295
uniprot id: X2HEU5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1196094:SALWKB2 RS08120
gene id: 1196094:SALWKB2_RS08120
uniprot id: X2H6G1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1196094:SALWKB2 RS07410
gene id: 1196094:SALWKB2_RS07410
uniprot id: X2H8X7
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

1196094:SALWKB2 RS04680
gene id: 1196094:SALWKB2_RS04680
uniprot id: X2HB46
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1196094:SALWKB2 RS08385
gene id: 1196094:SALWKB2_RS08385
uniprot id: X2H9J3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

1196094:SALWKB2 RS09210
gene id: 1196094:SALWKB2_RS09210
uniprot id: X2HDQ3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1196094:SALWKB2 RS04400
gene id: 1196094:SALWKB2_RS04400
uniprot id: X2HFB6
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.

1196094:SALWKB2 RS05245
gene id: 1196094:SALWKB2_RS05245
uniprot id: X2H7L8
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS06230
gene id: 1196094:SALWKB2_RS06230
uniprot id: X2H5F8
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS10300
gene id: 1196094:SALWKB2_RS10300
uniprot id: X2H7M7
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS00735
gene id: 1196094:SALWKB2_RS00735
uniprot id: X2H8P4
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1196094:SALWKB2 RS08455
gene id: 1196094:SALWKB2_RS08455
uniprot id: X2H6P4
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1196094:SALWKB2 RS01425
gene id: 1196094:SALWKB2_RS01425
uniprot id: X2H5G3
names: Similarity
messages: Belongs to the DEAD box helicase family.

1196094:SALWKB2 RS03405
gene id: 1196094:SALWKB2_RS03405
uniprot id: X2HA66
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1196094:SALWKB2 RS01635
gene id: 1196094:SALWKB2_RS01635
uniprot id: X2H9D9
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1196094:SALWKB2 RS06830
gene id: 1196094:SALWKB2_RS06830
uniprot id: X2HCF6
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.

1196094:SALWKB2 RS12140
gene id: 1196094:SALWKB2_RS12140
uniprot id: X2HE62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
messages: Cell surface

1196094:SALWKB2 RS02300
gene id: 1196094:SALWKB2_RS02300
uniprot id: X2H9I5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1196094:SALWKB2 RS04170
gene id: 1196094:SALWKB2_RS04170
uniprot id: X2HAV4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1196094:SALWKB2 RS10805
gene id: 1196094:SALWKB2_RS10805
uniprot id: X2HEF6
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1196094:SALWKB2 RS01215
gene id: 1196094:SALWKB2_RS01215
uniprot id: X2H954
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxine kinase family. PdxY subfamily.
messages: Homodimer.
messages: Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP.

1196094:SALWKB2 RS05675
gene id: 1196094:SALWKB2_RS05675
uniprot id: X2HFZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1196094:SALWKB2 RS03550
gene id: 1196094:SALWKB2_RS03550
uniprot id: X2HAG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane
messages: Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.

1196094:SALWKB2 RS08125
gene id: 1196094:SALWKB2_RS08125
uniprot id: X2H9B7
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1196094:SALWKB2 RS03225
gene id: 1196094:SALWKB2_RS03225
uniprot id: X2HA93
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

1196094:SALWKB2 RS03430
gene id: 1196094:SALWKB2_RS03430
uniprot id: X2HA71
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1196094:SALWKB2 RS01200
gene id: 1196094:SALWKB2_RS01200
uniprot id: X2H8Z0
names: Similarity
messages: Belongs to the YggT family.

1196094:SALWKB2 RS02850
gene id: 1196094:SALWKB2_RS02850
uniprot id: X2H3G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

1196094:SALWKB2 RS01630
gene id: 1196094:SALWKB2_RS01630
uniprot id: X2H2V8
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1196094:SALWKB2 RS09910
gene id: 1196094:SALWKB2_RS09910
uniprot id: X2HIF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1196094:SALWKB2 RS01850
gene id: 1196094:SALWKB2_RS01850
uniprot id: X2HDV3
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

1196094:SALWKB2 RS07270
gene id: 1196094:SALWKB2_RS07270
uniprot id: X2HCM1
names: Caution
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1196094:SALWKB2 RS01580
gene id: 1196094:SALWKB2_RS01580
uniprot id: X2H2V0
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS06235
gene id: 1196094:SALWKB2_RS06235
uniprot id: X2H8D1
names: Similarity
messages: Belongs to the thioredoxin family.

1196094:SALWKB2 RS04060
gene id: 1196094:SALWKB2_RS04060
uniprot id: X2H6Z7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1196094:SALWKB2 RS05080
gene id: 1196094:SALWKB2_RS05080
uniprot id: X2HB22
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.

1196094:SALWKB2 RS04180
gene id: 1196094:SALWKB2_RS04180
uniprot id: X2H4A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family.
messages: Periplasm

1196094:SALWKB2 RS09905
gene id: 1196094:SALWKB2_RS09905
uniprot id: X2HAC6
names: Similarity
messages: Belongs to the FeoA family.

1196094:SALWKB2 RS05910
gene id: 1196094:SALWKB2_RS05910
uniprot id: X2H840
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1196094:SALWKB2 RS05770
gene id: 1196094:SALWKB2_RS05770
uniprot id: X2HG22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1196094:SALWKB2 RS05055
gene id: 1196094:SALWKB2_RS05055
uniprot id: X2HB18
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1196094:SALWKB2 RS10810
gene id: 1196094:SALWKB2_RS10810
uniprot id: X2H7Y9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1196094:SALWKB2 RS08020
gene id: 1196094:SALWKB2_RS08020
uniprot id: X2HCR1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1196094:SALWKB2 RS03760
gene id: 1196094:SALWKB2_RS03760
uniprot id: X2HAG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1196094:SALWKB2 RS06695
gene id: 1196094:SALWKB2_RS06695
uniprot id: X2H8L6
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1196094:SALWKB2 RS01060
gene id: 1196094:SALWKB2_RS01060
uniprot id: X2H8W3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1196094:SALWKB2 RS09085
gene id: 1196094:SALWKB2_RS09085
uniprot id: X2HA04
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS00765
gene id: 1196094:SALWKB2_RS00765
uniprot id: X2H2B4
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1196094:SALWKB2 RS09175
gene id: 1196094:SALWKB2_RS09175
uniprot id: X2HA19
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

1196094:SALWKB2 RS01370
gene id: 1196094:SALWKB2_RS01370
uniprot id: X2H5F6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1196094:SALWKB2 RS00375
gene id: 1196094:SALWKB2_RS00375
uniprot id: X2H4T2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1196094:SALWKB2 RS02970
gene id: 1196094:SALWKB2_RS02970
uniprot id: X2H3I3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1196094:SALWKB2 RS02825
gene id: 1196094:SALWKB2_RS02825
uniprot id: X2H3F8
names: Similarity
messages: Belongs to the HesB/IscA family.

1196094:SALWKB2 RS08695
gene id: 1196094:SALWKB2_RS08695
uniprot id: X2HDG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1196094:SALWKB2 RS10580
gene id: 1196094:SALWKB2_RS10580
uniprot id: X2HE97
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.

1196094:SALWKB2 RS01680
gene id: 1196094:SALWKB2_RS01680
uniprot id: X2H9E7
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

1196094:SALWKB2 RS06300
gene id: 1196094:SALWKB2_RS06300
uniprot id: X2HGG9
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1196094:SALWKB2 RS08495
gene id: 1196094:SALWKB2_RS08495
uniprot id: X2HDB6
names: Similarity
messages: Belongs to the RutC family.

1196094:SALWKB2 RS05560
gene id: 1196094:SALWKB2_RS05560
uniprot id: X2HBM8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

1196094:SALWKB2 RS08160
gene id: 1196094:SALWKB2_RS08160
uniprot id: X2HD50
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1196094:SALWKB2 RS00305
gene id: 1196094:SALWKB2_RS00305
uniprot id: X2H225
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1196094:SALWKB2 RS06820
gene id: 1196094:SALWKB2_RS06820
uniprot id: X2H8N4
names: Similarity
messages: Belongs to the peptidase C40 family.

1196094:SALWKB2 RS10305
gene id: 1196094:SALWKB2_RS10305
uniprot id: X2HAJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1196094:SALWKB2 RS10430
gene id: 1196094:SALWKB2_RS10430
uniprot id: X2H7P7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1196094:SALWKB2 RS00125
gene id: 1196094:SALWKB2_RS00125
uniprot id: X2H1Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1196094:SALWKB2 RS00080
gene id: 1196094:SALWKB2_RS00080
uniprot id: X2H1Y8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

1196094:SALWKB2 RS01080
gene id: 1196094:SALWKB2_RS01080
uniprot id: X2H925
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1196094:SALWKB2 RS05985
gene id: 1196094:SALWKB2_RS05985
uniprot id: X2H861
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS00410
gene id: 1196094:SALWKB2_RS00410
uniprot id: X2H8Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1196094:SALWKB2 RS08010
gene id: 1196094:SALWKB2_RS08010
uniprot id: X2HHC4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1196094:SALWKB2 RS05225
gene id: 1196094:SALWKB2_RS05225
uniprot id: X2HFP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

1196094:SALWKB2 RS08675
gene id: 1196094:SALWKB2_RS08675
uniprot id: X2HD68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1196094:SALWKB2 RS04110
gene id: 1196094:SALWKB2_RS04110
uniprot id: X2H707
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1196094:SALWKB2 RS04100
gene id: 1196094:SALWKB2_RS04100
uniprot id: X2HAL3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1196094:SALWKB2 RS07350
gene id: 1196094:SALWKB2_RS07350
uniprot id: X2HCA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1196094:SALWKB2 RS05330
gene id: 1196094:SALWKB2_RS05330
uniprot id: X2HBH0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1196094:SALWKB2 RS04665
gene id: 1196094:SALWKB2_RS04665
uniprot id: X2H4I5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1196094:SALWKB2 RS08435
gene id: 1196094:SALWKB2_RS08435
uniprot id: X2H9K6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

1196094:SALWKB2 RS05810
gene id: 1196094:SALWKB2_RS05810
uniprot id: X2H545
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1196094:SALWKB2 RS07035
gene id: 1196094:SALWKB2_RS07035
uniprot id: X2HGT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane

1196094:SALWKB2 RS03655
gene id: 1196094:SALWKB2_RS03655
uniprot id: X2HAC8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1196094:SALWKB2 RS10800
gene id: 1196094:SALWKB2_RS10800
uniprot id: X2HEI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1196094:SALWKB2 RS08155
gene id: 1196094:SALWKB2_RS08155
uniprot id: X2HHF8
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1196094:SALWKB2 RS07580
gene id: 1196094:SALWKB2_RS07580
uniprot id: X2HCF7
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1196094:SALWKB2 RS03055
gene id: 1196094:SALWKB2_RS03055
uniprot id: X2HEH2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1196094:SALWKB2 RS08330
gene id: 1196094:SALWKB2_RS08330
uniprot id: X2H6L3
names: Similarity
messages: Belongs to the MlaA family.

1196094:SALWKB2 RS06200
gene id: 1196094:SALWKB2_RS06200
uniprot id: X2HBQ7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1196094:SALWKB2 RS05980
gene id: 1196094:SALWKB2_RS05980
uniprot id: X2H591
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS10695
gene id: 1196094:SALWKB2_RS10695
uniprot id: X2HAU7
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS00020
gene id: 1196094:SALWKB2_RS00020
uniprot id: X2H8B0
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Homotetramer.

1196094:SALWKB2 RS07860
gene id: 1196094:SALWKB2_RS07860
uniprot id: X2H694
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1196094:SALWKB2 RS10280
gene id: 1196094:SALWKB2_RS10280
uniprot id: X2H7M3
names: Similarity
messages: Belongs to the EfeM/EfeO family.

1196094:SALWKB2 RS07065
gene id: 1196094:SALWKB2_RS07065
uniprot id: X2H5W0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1196094:SALWKB2 RS11065
gene id: 1196094:SALWKB2_RS11065
uniprot id: X2H862
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1196094:SALWKB2 RS03155
gene id: 1196094:SALWKB2_RS03155
uniprot id: X2HA77
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1196094:SALWKB2 RS03625
gene id: 1196094:SALWKB2_RS03625
uniprot id: X2HAI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1196094:SALWKB2 RS05175
gene id: 1196094:SALWKB2_RS05175
uniprot id: X2HFP2
names: Similarity
messages: Belongs to the UPF0307 family.

1196094:SALWKB2 RS00790
gene id: 1196094:SALWKB2_RS00790
uniprot id: X2H2C6
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1196094:SALWKB2 RS04245
gene id: 1196094:SALWKB2_RS04245
uniprot id: X2HAN1
names: Similarity
messages: Belongs to the P(II) protein family.

1196094:SALWKB2 RS00185
gene id: 1196094:SALWKB2_RS00185
uniprot id: X2H4P9
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1196094:SALWKB2 RS06555
gene id: 1196094:SALWKB2_RS06555
uniprot id: X2HBX6
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1196094:SALWKB2 RS06330
gene id: 1196094:SALWKB2_RS06330
uniprot id: X2HC81
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1196094:SALWKB2 RS01940
gene id: 1196094:SALWKB2_RS01940
uniprot id: X2H5P3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1196094:SALWKB2 RS01490
gene id: 1196094:SALWKB2_RS01490
uniprot id: X2H941
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1196094:SALWKB2 RS01800
gene id: 1196094:SALWKB2_RS01800
uniprot id: X2HDU5
names: Similarity
messages: Belongs to the Gfa family.

1196094:SALWKB2 RS11150
gene id: 1196094:SALWKB2_RS11150
uniprot id: X2H886
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

1196094:SALWKB2 RS08855
gene id: 1196094:SALWKB2_RS08855
uniprot id: X2HDB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

1196094:SALWKB2 RS03485
gene id: 1196094:SALWKB2_RS03485
uniprot id: X2H3U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1196094:SALWKB2 RS03165
gene id: 1196094:SALWKB2_RS03165
uniprot id: X2H3L9
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

1196094:SALWKB2 RS06855
gene id: 1196094:SALWKB2_RS06855
uniprot id: X2HCG0
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS11470
gene id: 1196094:SALWKB2_RS11470
uniprot id: X2H8F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
messages: Cell surface

1196094:SALWKB2 RS07275
gene id: 1196094:SALWKB2_RS07275
uniprot id: X2HC92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1196094:SALWKB2 RS07815
gene id: 1196094:SALWKB2_RS07815
uniprot id: X2H685
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

1196094:SALWKB2 RS02780
gene id: 1196094:SALWKB2_RS02780
uniprot id: X2H647
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1196094:SALWKB2 RS06760
gene id: 1196094:SALWKB2_RS06760
uniprot id: X2HC04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1196094:SALWKB2 RS02240
gene id: 1196094:SALWKB2_RS02240
uniprot id: X2H5V7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1196094:SALWKB2 RS02100
gene id: 1196094:SALWKB2_RS02100
uniprot id: X2H5S9
names: Similarity
messages: Belongs to the UPF0250 family.

1196094:SALWKB2 RS05570
gene id: 1196094:SALWKB2_RS05570
uniprot id: X2H4Y7
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

1196094:SALWKB2 RS08085
gene id: 1196094:SALWKB2_RS08085
uniprot id: X2HHE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1196094:SALWKB2 RS01305
gene id: 1196094:SALWKB2_RS01305
uniprot id: X2H989
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1196094:SALWKB2 RS03345
gene id: 1196094:SALWKB2_RS03345
uniprot id: X2H6H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1196094:SALWKB2 RS03850
gene id: 1196094:SALWKB2_RS03850
uniprot id: X2HAQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1196094:SALWKB2 RS06140
gene id: 1196094:SALWKB2_RS06140
uniprot id: X2HGA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1196094:SALWKB2 RS02765
gene id: 1196094:SALWKB2_RS02765
uniprot id: X2H9Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1196094:SALWKB2 RS11035
gene id: 1196094:SALWKB2_RS11035
uniprot id: X2HJ71
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1196094:SALWKB2 RS10180
gene id: 1196094:SALWKB2_RS10180
uniprot id: X2HIK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1196094:SALWKB2 RS01110
gene id: 1196094:SALWKB2_RS01110
uniprot id: X2H8X3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1196094:SALWKB2 RS03670
gene id: 1196094:SALWKB2_RS03670
uniprot id: X2HAJ5
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1196094:SALWKB2 RS11420
gene id: 1196094:SALWKB2_RS11420
uniprot id: X2HEX5
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1196094:SALWKB2 RS00405
gene id: 1196094:SALWKB2_RS00405
uniprot id: X2HCZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1196094:SALWKB2 RS04175
gene id: 1196094:SALWKB2_RS04175
uniprot id: X2HAM1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1196094:SALWKB2 RS03105
gene id: 1196094:SALWKB2_RS03105
uniprot id: X2HA67
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

1196094:SALWKB2 RS11265
gene id: 1196094:SALWKB2_RS11265
uniprot id: X2HJH4
names: Similarity
messages: Belongs to the peptidase U62 family.

1196094:SALWKB2 RS07145
gene id: 1196094:SALWKB2_RS07145
uniprot id: X2HGV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1196094:SALWKB2 RS06320
gene id: 1196094:SALWKB2_RS06320
uniprot id: X2H8G6
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1196094:SALWKB2 RS04660
gene id: 1196094:SALWKB2_RS04660
uniprot id: X2HAV3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1196094:SALWKB2 RS05565
gene id: 1196094:SALWKB2_RS05565
uniprot id: X2HB99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1196094:SALWKB2 RS08535
gene id: 1196094:SALWKB2_RS08535
uniprot id: X2HHR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1196094:SALWKB2 RS05730
gene id: 1196094:SALWKB2_RS05730
uniprot id: X2HBE1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1196094:SALWKB2 RS09240
gene id: 1196094:SALWKB2_RS09240
uniprot id: X2H764
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1196094:SALWKB2 RS07975
gene id: 1196094:SALWKB2_RS07975
uniprot id: X2HCP8
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS08015
gene id: 1196094:SALWKB2_RS08015
uniprot id: X2HD21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1196094:SALWKB2 RS08305
gene id: 1196094:SALWKB2_RS08305
uniprot id: X2H6K7
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1196094:SALWKB2 RS07710
gene id: 1196094:SALWKB2_RS07710
uniprot id: X2HH60
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1196094:SALWKB2 RS00350
gene id: 1196094:SALWKB2_RS00350
uniprot id: X2H4S5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

1196094:SALWKB2 RS08885
gene id: 1196094:SALWKB2_RS08885
uniprot id: X2H706
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1196094:SALWKB2 RS07160
gene id: 1196094:SALWKB2_RS07160
uniprot id: X2H5X9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell.

1196094:SALWKB2 RS04480
gene id: 1196094:SALWKB2_RS04480
uniprot id: X2HFC8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1196094:SALWKB2 RS05085
gene id: 1196094:SALWKB2_RS05085
uniprot id: X2H4Q3
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1196094:SALWKB2 RS01065
gene id: 1196094:SALWKB2_RS01065
uniprot id: X2H2J0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1196094:SALWKB2 RS06075
gene id: 1196094:SALWKB2_RS06075
uniprot id: X2HC05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

1196094:SALWKB2 RS00085
gene id: 1196094:SALWKB2_RS00085
uniprot id: X2H4N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

1196094:SALWKB2 RS05420
gene id: 1196094:SALWKB2_RS05420
uniprot id: X2HFT8
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS00425
gene id: 1196094:SALWKB2_RS00425
uniprot id: X2H4U4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1196094:SALWKB2 RS10020
gene id: 1196094:SALWKB2_RS10020
uniprot id: X2H7I2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1196094:SALWKB2 RS03250
gene id: 1196094:SALWKB2_RS03250
uniprot id: X2HA29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

1196094:SALWKB2 RS04210
gene id: 1196094:SALWKB2_RS04210
uniprot id: X2H726
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1196094:SALWKB2 RS01675
gene id: 1196094:SALWKB2_RS01675
uniprot id: X2HDS9
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

1196094:SALWKB2 RS01525
gene id: 1196094:SALWKB2_RS01525
uniprot id: X2HDQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1196094:SALWKB2 RS02515
gene id: 1196094:SALWKB2_RS02515
uniprot id: X2HE68
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

1196094:SALWKB2 RS07405
gene id: 1196094:SALWKB2_RS07405
uniprot id: X2H617
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1196094:SALWKB2 RS10815
gene id: 1196094:SALWKB2_RS10815
uniprot id: X2HAY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1196094:SALWKB2 RS07455
gene id: 1196094:SALWKB2_RS07455
uniprot id: X2H625
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Homodimer.

1196094:SALWKB2 RS05950
gene id: 1196094:SALWKB2_RS05950
uniprot id: X2HBJ8
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS03085
gene id: 1196094:SALWKB2_RS03085
uniprot id: X2HA62
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1196094:SALWKB2 RS00445
gene id: 1196094:SALWKB2_RS00445
uniprot id: X2H8I7
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

1196094:SALWKB2 RS03950
gene id: 1196094:SALWKB2_RS03950
uniprot id: X2HF38
names: Similarity
messages: Belongs to the peptidase S58 family.

1196094:SALWKB2 RS04065
gene id: 1196094:SALWKB2_RS04065
uniprot id: X2HF58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

1196094:SALWKB2 RS10730
gene id: 1196094:SALWKB2_RS10730
uniprot id: X2HED5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1196094:SALWKB2 RS03445
gene id: 1196094:SALWKB2_RS03445
uniprot id: X2HEQ7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1196094:SALWKB2 RS06010
gene id: 1196094:SALWKB2_RS06010
uniprot id: X2H866
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1196094:SALWKB2 RS08415
gene id: 1196094:SALWKB2_RS08415
uniprot id: X2HHM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1196094:SALWKB2 RS04650
gene id: 1196094:SALWKB2_RS04650
uniprot id: X2H7A8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1196094:SALWKB2 RS02090
gene id: 1196094:SALWKB2_RS02090
uniprot id: X2H9E0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1196094:SALWKB2 RS05895
gene id: 1196094:SALWKB2_RS05895
uniprot id: X2HBV6
names: Caution
names: Function
names: Similarity
messages: Belongs to the Dus family. DusC subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1196094:SALWKB2 RS01750
gene id: 1196094:SALWKB2_RS01750
uniprot id: X2HDT8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1196094:SALWKB2 RS08590
gene id: 1196094:SALWKB2_RS08590
uniprot id: X2HHT1
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

1196094:SALWKB2 RS11605
gene id: 1196094:SALWKB2_RS11605
uniprot id: X2HAS8
names: Subcellular Location Annotation
messages: Cell inner membrane

1196094:SALWKB2 RS05815
gene id: 1196094:SALWKB2_RS05815
uniprot id: X2H810
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1196094:SALWKB2 RS01790
gene id: 1196094:SALWKB2_RS01790
uniprot id: X2H2Y1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1196094:SALWKB2 RS09120
gene id: 1196094:SALWKB2_RS09120
uniprot id: X2HDF4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1196094:SALWKB2 RS05445
gene id: 1196094:SALWKB2_RS05445
uniprot id: X2HFU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1196094:SALWKB2 RS07990
gene id: 1196094:SALWKB2_RS07990
uniprot id: X2HD16
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1196094:SALWKB2 RS07045
gene id: 1196094:SALWKB2_RS07045
uniprot id: X2HC45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1196094:SALWKB2 RS05635
gene id: 1196094:SALWKB2_RS05635
uniprot id: X2HBP6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1196094:SALWKB2 RS06995
gene id: 1196094:SALWKB2_RS06995
uniprot id: X2H5U9
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

1196094:SALWKB2 RS02310
gene id: 1196094:SALWKB2_RS02310
uniprot id: X2H5X0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1196094:SALWKB2 RS09965
gene id: 1196094:SALWKB2_RS09965
uniprot id: X2H7G9
names: Similarity
messages: Belongs to the UPF0246 family.

1196094:SALWKB2 RS10900
gene id: 1196094:SALWKB2_RS10900
uniprot id: X2HEK6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1196094:SALWKB2 RS09980
gene id: 1196094:SALWKB2_RS09980
uniprot id: X2HDU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1196094:SALWKB2 RS01615
gene id: 1196094:SALWKB2_RS01615
uniprot id: X2HDR7
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

1196094:SALWKB2 RS05115
gene id: 1196094:SALWKB2_RS05115
uniprot id: X2HBC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1196094:SALWKB2 RS08235
gene id: 1196094:SALWKB2_RS08235
uniprot id: X2H6J2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Involved in the heme biosynthesis. Catalyzes the anaerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen III to yield the vinyl groups in protoporphyrinogen IX.
messages: Monomer.

1196094:SALWKB2 RS08880
gene id: 1196094:SALWKB2_RS08880
uniprot id: X2HDC2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1196094:SALWKB2 RS03500
gene id: 1196094:SALWKB2_RS03500
uniprot id: X2HA89
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

1196094:SALWKB2 RS04990
gene id: 1196094:SALWKB2_RS04990
uniprot id: X2H7H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1196094:SALWKB2 RS06580
gene id: 1196094:SALWKB2_RS06580
uniprot id: X2HBX9
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

1196094:SALWKB2 RS06950
gene id: 1196094:SALWKB2_RS06950
uniprot id: X2HGS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1196094:SALWKB2 RS10880
gene id: 1196094:SALWKB2_RS10880
uniprot id: X2HEH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1196094:SALWKB2 RS07685
gene id: 1196094:SALWKB2_RS07685
uniprot id: X2HH54
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1196094:SALWKB2 RS01745
gene id: 1196094:SALWKB2_RS01745
uniprot id: X2H5K6
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS00845
gene id: 1196094:SALWKB2_RS00845
uniprot id: X2H521
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS06060
gene id: 1196094:SALWKB2_RS06060
uniprot id: X2H5B2
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1196094:SALWKB2 RS09585
gene id: 1196094:SALWKB2_RS09585
uniprot id: X2HDV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1196094:SALWKB2 RS05405
gene id: 1196094:SALWKB2_RS05405
uniprot id: X2HBI6
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1196094:SALWKB2 RS02950
gene id: 1196094:SALWKB2_RS02950
uniprot id: X2H3I0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1196094:SALWKB2 RS06245
gene id: 1196094:SALWKB2_RS06245
uniprot id: X2HC48
names: Similarity
messages: Belongs to the UPF0246 family.

1196094:SALWKB2 RS03365
gene id: 1196094:SALWKB2_RS03365
uniprot id: X2H6I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1196094:SALWKB2 RS09030
gene id: 1196094:SALWKB2_RS09030
uniprot id: X2H729
names: Similarity
messages: Belongs to the LOG family.

1196094:SALWKB2 RS04305
gene id: 1196094:SALWKB2_RS04305
uniprot id: X2H745
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1196094:SALWKB2 RS11020
gene id: 1196094:SALWKB2_RS11020
uniprot id: X2HJ64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1196094:SALWKB2 RS01540
gene id: 1196094:SALWKB2_RS01540
uniprot id: X2H5H4
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1196094:SALWKB2 RS07235
gene id: 1196094:SALWKB2_RS07235
uniprot id: X2H8V4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1196094:SALWKB2 RS07490
gene id: 1196094:SALWKB2_RS07490
uniprot id: X2HH12
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1196094:SALWKB2 RS07380
gene id: 1196094:SALWKB2_RS07380
uniprot id: X2H613
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1196094:SALWKB2 RS11440
gene id: 1196094:SALWKB2_RS11440
uniprot id: X2HJJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1196094:SALWKB2 RS05630
gene id: 1196094:SALWKB2_RS05630
uniprot id: X2HFY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1196094:SALWKB2 RS02155
gene id: 1196094:SALWKB2_RS02155
uniprot id: X2H9F4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1196094:SALWKB2 RS08025
gene id: 1196094:SALWKB2_RS08025
uniprot id: X2H6D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1196094:SALWKB2 RS09035
gene id: 1196094:SALWKB2_RS09035
uniprot id: X2H9Z8
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1196094:SALWKB2 RS10295
gene id: 1196094:SALWKB2_RS10295
uniprot id: X2HE13
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS00740
gene id: 1196094:SALWKB2_RS00740
uniprot id: X2H2A8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1196094:SALWKB2 RS09865
gene id: 1196094:SALWKB2_RS09865
uniprot id: X2HDZ2
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family. HpaC subfamily.

1196094:SALWKB2 RS07805
gene id: 1196094:SALWKB2_RS07805
uniprot id: X2HCX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1196094:SALWKB2 RS05370
gene id: 1196094:SALWKB2_RS05370
uniprot id: X2H4V0
names: Similarity
messages: Belongs to the ArsC family.

1196094:SALWKB2 RS05205
gene id: 1196094:SALWKB2_RS05205
uniprot id: X2HBD9
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1196094:SALWKB2 RS11325
gene id: 1196094:SALWKB2_RS11325
uniprot id: X2H8D8
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

1196094:SALWKB2 RS10720
gene id: 1196094:SALWKB2_RS10720
uniprot id: X2HIX3
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1196094:SALWKB2 RS05195
gene id: 1196094:SALWKB2_RS05195
uniprot id: X2H7K8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

1196094:SALWKB2 RS01605
gene id: 1196094:SALWKB2_RS01605
uniprot id: X2H2V4
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS10565
gene id: 1196094:SALWKB2_RS10565
uniprot id: X2HAR3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

1196094:SALWKB2 RS01825
gene id: 1196094:SALWKB2_RS01825
uniprot id: X2HDV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1196094:SALWKB2 RS06310
gene id: 1196094:SALWKB2_RS06310
uniprot id: X2HBU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

1196094:SALWKB2 RS10850
gene id: 1196094:SALWKB2_RS10850
uniprot id: X2HEJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1196094:SALWKB2 RS05295
gene id: 1196094:SALWKB2_RS05295
uniprot id: X2H7M6
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1196094:SALWKB2 RS01090
gene id: 1196094:SALWKB2_RS01090
uniprot id: X2H2J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1196094:SALWKB2 RS05540
gene id: 1196094:SALWKB2_RS05540
uniprot id: X2HB93
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1196094:SALWKB2 RS03530
gene id: 1196094:SALWKB2_RS03530
uniprot id: X2H3V9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1196094:SALWKB2 RS08960
gene id: 1196094:SALWKB2_RS08960
uniprot id: X2HI17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1196094:SALWKB2 RS08910
gene id: 1196094:SALWKB2_RS08910
uniprot id: X2HI11
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1196094:SALWKB2 RS00370
gene id: 1196094:SALWKB2_RS00370
uniprot id: X2H238
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1196094:SALWKB2 RS06750
gene id: 1196094:SALWKB2_RS06750
uniprot id: X2HGN8
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

1196094:SALWKB2 RS00980
gene id: 1196094:SALWKB2_RS00980
uniprot id: X2H904
names: Similarity
messages: Belongs to the SlyX family.

1196094:SALWKB2 RS02130
gene id: 1196094:SALWKB2_RS02130
uniprot id: X2H9M5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1196094:SALWKB2 RS08070
gene id: 1196094:SALWKB2_RS08070
uniprot id: X2HCS3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

1196094:SALWKB2 RS04465
gene id: 1196094:SALWKB2_RS04465
uniprot id: X2HAS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

1196094:SALWKB2 RS03380
gene id: 1196094:SALWKB2_RS03380
uniprot id: X2HA61
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS01225
gene id: 1196094:SALWKB2_RS01225
uniprot id: X2H2M8
names: Similarity
messages: Belongs to the GSP E family.

1196094:SALWKB2 RS10775
gene id: 1196094:SALWKB2_RS10775
uniprot id: X2HEI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1196094:SALWKB2 RS05750
gene id: 1196094:SALWKB2_RS05750
uniprot id: X2HBS4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1196094:SALWKB2 RS02315
gene id: 1196094:SALWKB2_RS02315
uniprot id: X2HE39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1196094:SALWKB2 RS11695
gene id: 1196094:SALWKB2_RS11695
uniprot id: X2HCJ2
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

1196094:SALWKB2 RS10040
gene id: 1196094:SALWKB2_RS10040
uniprot id: X2HDV9
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1196094:SALWKB2 RS08895
gene id: 1196094:SALWKB2_RS08895
uniprot id: X2HI09
names: Similarity
messages: Belongs to the peptidase S49 family.

1196094:SALWKB2 RS00390
gene id: 1196094:SALWKB2_RS00390
uniprot id: X2H8H5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1196094:SALWKB2 RS03175
gene id: 1196094:SALWKB2_RS03175
uniprot id: X2HEJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1196094:SALWKB2 RS00205
gene id: 1196094:SALWKB2_RS00205
uniprot id: X2H210
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1196094:SALWKB2 RS06225
gene id: 1196094:SALWKB2_RS06225
uniprot id: X2HBR3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1196094:SALWKB2 RS05795
gene id: 1196094:SALWKB2_RS05795
uniprot id: X2HG27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1196094:SALWKB2 RS06465
gene id: 1196094:SALWKB2_RS06465
uniprot id: X2H5L2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1196094:SALWKB2 RS11060
gene id: 1196094:SALWKB2_RS11060
uniprot id: X2HJ78
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1196094:SALWKB2 RS07030
gene id: 1196094:SALWKB2_RS07030
uniprot id: X2H8R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1196094:SALWKB2 RS05390
gene id: 1196094:SALWKB2_RS05390
uniprot id: X2H4V5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

1196094:SALWKB2 RS10890
gene id: 1196094:SALWKB2_RS10890
uniprot id: X2HB01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1196094:SALWKB2 RS03465
gene id: 1196094:SALWKB2_RS03465
uniprot id: X2HER2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1196094:SALWKB2 RS10030
gene id: 1196094:SALWKB2_RS10030
uniprot id: X2HII1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1196094:SALWKB2 RS10075
gene id: 1196094:SALWKB2_RS10075
uniprot id: X2HAF7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1196094:SALWKB2 RS08000
gene id: 1196094:SALWKB2_RS08000
uniprot id: X2H6C8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1196094:SALWKB2 RS10440
gene id: 1196094:SALWKB2_RS10440
uniprot id: X2HIR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1196094:SALWKB2 RS12130
gene id: 1196094:SALWKB2_RS12130
uniprot id: X2HFJ9
names: Similarity
messages: Belongs to the ArsC family.

1196094:SALWKB2 RS08465
gene id: 1196094:SALWKB2_RS08465
uniprot id: X2HHP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1196094:SALWKB2 RS08720
gene id: 1196094:SALWKB2_RS08720
uniprot id: X2HDH0
names: Similarity
messages: Belongs to the PhoH family.

1196094:SALWKB2 RS09550
gene id: 1196094:SALWKB2_RS09550
uniprot id: X2HDV4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1196094:SALWKB2 RS05180
gene id: 1196094:SALWKB2_RS05180
uniprot id: X2HBD3
names: Similarity
messages: Belongs to the peptidase U62 family.

1196094:SALWKB2 RS07785
gene id: 1196094:SALWKB2_RS07785
uniprot id: X2HCK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1196094:SALWKB2 RS03275
gene id: 1196094:SALWKB2_RS03275
uniprot id: X2HA35
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1196094:SALWKB2 RS00385
gene id: 1196094:SALWKB2_RS00385
uniprot id: X2H8P7
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1196094:SALWKB2 RS03750
gene id: 1196094:SALWKB2_RS03750
uniprot id: X2HEZ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1196094:SALWKB2 RS11000
gene id: 1196094:SALWKB2_RS11000
uniprot id: X2HEM8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1196094:SALWKB2 RS00920
gene id: 1196094:SALWKB2_RS00920
uniprot id: X2H531
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS05380
gene id: 1196094:SALWKB2_RS05380
uniprot id: X2HFS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1196094:SALWKB2 RS03835
gene id: 1196094:SALWKB2_RS03835
uniprot id: X2H454
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS08205
gene id: 1196094:SALWKB2_RS08205
uniprot id: X2HCW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1196094:SALWKB2 RS10035
gene id: 1196094:SALWKB2_RS10035
uniprot id: X2HE29
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1196094:SALWKB2 RS08190
gene id: 1196094:SALWKB2_RS08190
uniprot id: X2H9D8
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1196094:SALWKB2 RS02975
gene id: 1196094:SALWKB2_RS02975
uniprot id: X2H681
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1196094:SALWKB2 RS03110
gene id: 1196094:SALWKB2_RS03110
uniprot id: X2H9Y8
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1196094:SALWKB2 RS07610
gene id: 1196094:SALWKB2_RS07610
uniprot id: X2HH40
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS04230
gene id: 1196094:SALWKB2_RS04230
uniprot id: X2H730
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1196094:SALWKB2 RS07060
gene id: 1196094:SALWKB2_RS07060
uniprot id: X2HC49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1196094:SALWKB2 RS06595
gene id: 1196094:SALWKB2_RS06595
uniprot id: X2HGL1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

1196094:SALWKB2 RS11110
gene id: 1196094:SALWKB2_RS11110
uniprot id: X2H875
names: Cofactor
names: Function
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.

1196094:SALWKB2 RS00015
gene id: 1196094:SALWKB2_RS00015
uniprot id: X2H8H2
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1196094:SALWKB2 RS00300
gene id: 1196094:SALWKB2_RS00300
uniprot id: X2H8F4
names: Subcellular Location Annotation
messages: Cytoplasm

1196094:SALWKB2 RS06730
gene id: 1196094:SALWKB2_RS06730
uniprot id: X2HCE3
names: Similarity
messages: Belongs to the WrbA family.

1196094:SALWKB2 RS10215
gene id: 1196094:SALWKB2_RS10215
uniprot id: X2HDZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the P-Pant transferase superfamily. EntD family.
messages: EntB, EntD, EntE, and EntF form a multienzyme complex called enterobactin synthase.
messages: Involved in the biosynthesis of the siderophore enterobactin (enterochelin), which is a macrocyclic trimeric lactone of N-(2,3-dihydroxybenzoyl)-serine. The serine trilactone serves as a scaffolding for the three catechol functionalities that provide hexadentate coordination for the tightly ligated iron(2+) atoms. Plays an essential role in the assembly of the enterobactin by catalyzing the transfer of the 4'-phosphopantetheine (Ppant) moiety from coenzyme A to the apo-domains of both EntB (ArCP domain) and EntF (PCP domain) to yield their holo-forms which make them competent for the activation of 2,3-dihydroxybenzoate (DHB) and L-serine, respectively.

1196094:SALWKB2 RS07800
gene id: 1196094:SALWKB2_RS07800
uniprot id: X2HH78
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1196094:SALWKB2 RS03240
gene id: 1196094:SALWKB2_RS03240
uniprot id: X2HEL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1196094:SALWKB2 RS08280
gene id: 1196094:SALWKB2_RS08280
uniprot id: X2H6K3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1196094:SALWKB2 RS05165
gene id: 1196094:SALWKB2_RS05165
uniprot id: X2H4R0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1196094:SALWKB2 RS03350
gene id: 1196094:SALWKB2_RS03350
uniprot id: X2HEN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1196094:SALWKB2 RS00245
gene id: 1196094:SALWKB2_RS00245
uniprot id: X2H8L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1196094:SALWKB2 RS08210
gene id: 1196094:SALWKB2_RS08210
uniprot id: X2H6I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1196094:SALWKB2 RS06135
gene id: 1196094:SALWKB2_RS06135
uniprot id: X2H8A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1196094:SALWKB2 RS00250
gene id: 1196094:SALWKB2_RS00250
uniprot id: X2H8E8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1196094:SALWKB2 RS08920
gene id: 1196094:SALWKB2_RS08920
uniprot id: X2HDC9
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1196094:SALWKB2 RS05925
gene id: 1196094:SALWKB2_RS05925
uniprot id: X2HBJ3
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

1196094:SALWKB2 RS07555
gene id: 1196094:SALWKB2_RS07555
uniprot id: X2HCF2
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1196094:SALWKB2 RS07140
gene id: 1196094:SALWKB2_RS07140
uniprot id: X2H8T7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1196094:SALWKB2 RS05735
gene id: 1196094:SALWKB2_RS05735
uniprot id: X2H527
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1196094:SALWKB2 RS07105
gene id: 1196094:SALWKB2_RS07105
uniprot id: X2HC56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1196094:SALWKB2 RS11055
gene id: 1196094:SALWKB2_RS11055
uniprot id: X2HB43
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1196094:SALWKB2 RS02295
gene id: 1196094:SALWKB2_RS02295
uniprot id: X2H9Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

1196094:SALWKB2 RS09180
gene id: 1196094:SALWKB2_RS09180
uniprot id: X2HI42
names: Similarity
messages: Belongs to the YciI family.

1196094:SALWKB2 RS10260
gene id: 1196094:SALWKB2_RS10260
uniprot id: X2H7L9
names: Similarity
messages: Belongs to the UPF0423 family.

1196094:SALWKB2 RS10825
gene id: 1196094:SALWKB2_RS10825
uniprot id: X2HEJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1196094:SALWKB2 RS08930
gene id: 1196094:SALWKB2_RS08930
uniprot id: X2H9Y3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1196094:SALWKB2 RS04555
gene id: 1196094:SALWKB2_RS04555
uniprot id: X2H790
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS10780
gene id: 1196094:SALWKB2_RS10780
uniprot id: X2HEE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1196094:SALWKB2 RS01155
gene id: 1196094:SALWKB2_RS01155
uniprot id: X2H944
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1196094:SALWKB2 RS11580
gene id: 1196094:SALWKB2_RS11580
uniprot id: X2HEL0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1196094:SALWKB2 RS00180
gene id: 1196094:SALWKB2_RS00180
uniprot id: X2H204
names: Similarity
messages: Belongs to the nitroreductase family.

1196094:SALWKB2 RS03535
gene id: 1196094:SALWKB2_RS03535
uniprot id: X2H6M8
names: Similarity
messages: Belongs to the Fur family.

1196094:SALWKB2 RS06085
gene id: 1196094:SALWKB2_RS06085
uniprot id: X2H5B9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1196094:SALWKB2 RS02350
gene id: 1196094:SALWKB2_RS02350
uniprot id: X2H9J4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell inner membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1196094:SALWKB2 RS01535
gene id: 1196094:SALWKB2_RS01535
uniprot id: X2H2U4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1196094:SALWKB2 RS06500
gene id: 1196094:SALWKB2_RS06500
uniprot id: X2HGJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

1196094:SALWKB2 RS10070
gene id: 1196094:SALWKB2_RS10070
uniprot id: X2H7J0
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1196094:SALWKB2 RS00415
gene id: 1196094:SALWKB2_RS00415
uniprot id: X2H8I1
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS07825
gene id: 1196094:SALWKB2_RS07825
uniprot id: X2HH81
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

1196094:SALWKB2 RS01045
gene id: 1196094:SALWKB2_RS01045
uniprot id: X2H8V7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1196094:SALWKB2 RS10795
gene id: 1196094:SALWKB2_RS10795
uniprot id: X2HIZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1196094:SALWKB2 RS03320
gene id: 1196094:SALWKB2_RS03320
uniprot id: X2H6H3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

1196094:SALWKB2 RS05650
gene id: 1196094:SALWKB2_RS05650
uniprot id: X2H7V3
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1196094:SALWKB2 RS00420
gene id: 1196094:SALWKB2_RS00420
uniprot id: X2H247
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1196094:SALWKB2 RS04275
gene id: 1196094:SALWKB2_RS04275
uniprot id: X2H4C5
names: Similarity
messages: Belongs to the RutC family.

1196094:SALWKB2 RS09015
gene id: 1196094:SALWKB2_RS09015
uniprot id: X2HI19
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS03955
gene id: 1196094:SALWKB2_RS03955
uniprot id: X2HAR8
names: Similarity
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.

1196094:SALWKB2 RS00090
gene id: 1196094:SALWKB2_RS00090
uniprot id: X2H8I9
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS05070
gene id: 1196094:SALWKB2_RS05070
uniprot id: X2HFM8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1196094:SALWKB2 RS07390
gene id: 1196094:SALWKB2_RS07390
uniprot id: X2HGZ4
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1196094:SALWKB2 RS02115
gene id: 1196094:SALWKB2_RS02115
uniprot id: X2H343
names: Similarity
messages: Belongs to the glutamate synthase family.

1196094:SALWKB2 RS03650
gene id: 1196094:SALWKB2_RS03650
uniprot id: X2HAJ0
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS09265
gene id: 1196094:SALWKB2_RS09265
uniprot id: X2HA34
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1196094:SALWKB2 RS10835
gene id: 1196094:SALWKB2_RS10835
uniprot id: X2H7Z7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1196094:SALWKB2 RS08965
gene id: 1196094:SALWKB2_RS08965
uniprot id: X2HDL4
names: Similarity
messages: Belongs to the fabD family.

1196094:SALWKB2 RS09140
gene id: 1196094:SALWKB2_RS09140
uniprot id: X2HDF9
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS03410
gene id: 1196094:SALWKB2_RS03410
uniprot id: X2H3S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1196094:SALWKB2 RS08515
gene id: 1196094:SALWKB2_RS08515
uniprot id: X2HHQ8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

1196094:SALWKB2 RS08500
gene id: 1196094:SALWKB2_RS08500
uniprot id: X2HD30
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1196094:SALWKB2 RS11465
gene id: 1196094:SALWKB2_RS11465
uniprot id: X2HJJ8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1196094:SALWKB2 RS08055
gene id: 1196094:SALWKB2_RS08055
uniprot id: X2H996
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

1196094:SALWKB2 RS08680
gene id: 1196094:SALWKB2_RS08680
uniprot id: X2H6U8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1196094:SALWKB2 RS00225
gene id: 1196094:SALWKB2_RS00225
uniprot id: X2H8E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1196094:SALWKB2 RS09635
gene id: 1196094:SALWKB2_RS09635
uniprot id: X2H7C4
names: Function
names: Similarity
messages: Belongs to the UbiT family.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Likely functions as an accessory factor.

1196094:SALWKB2 RS04085
gene id: 1196094:SALWKB2_RS04085
uniprot id: X2H702
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1196094:SALWKB2 RS07925
gene id: 1196094:SALWKB2_RS07925
uniprot id: X2HD01
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1196094:SALWKB2 RS00215
gene id: 1196094:SALWKB2_RS00215
uniprot id: X2HCV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1196094:SALWKB2 RS06800
gene id: 1196094:SALWKB2_RS06800
uniprot id: X2HGP8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1196094:SALWKB2 RS06545
gene id: 1196094:SALWKB2_RS06545
uniprot id: X2HGK2
names: Similarity
messages: Belongs to the HSP15 family.

1196094:SALWKB2 RS07855
gene id: 1196094:SALWKB2_RS07855
uniprot id: X2HCL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1196094:SALWKB2 RS00945
gene id: 1196094:SALWKB2_RS00945
uniprot id: X2H536
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1196094:SALWKB2 RS04390
gene id: 1196094:SALWKB2_RS04390
uniprot id: X2H4E4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

1196094:SALWKB2 RS00235
gene id: 1196094:SALWKB2_RS00235
uniprot id: X2H4Q9
names: Similarity
messages: Belongs to the Skp family.

1196094:SALWKB2 RS08850
gene id: 1196094:SALWKB2_RS08850
uniprot id: X2HDK1
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1196094:SALWKB2 RS07205
gene id: 1196094:SALWKB2_RS07205
uniprot id: X2H5Y7
names: Subcellular Location Annotation
messages: Secreted

1196094:SALWKB2 RS08050
gene id: 1196094:SALWKB2_RS08050
uniprot id: X2HCR7
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1196094:SALWKB2 RS06655
gene id: 1196094:SALWKB2_RS06655
uniprot id: X2H8K9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

1196094:SALWKB2 RS03665
gene id: 1196094:SALWKB2_RS03665
uniprot id: X2HEV1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1196094:SALWKB2 RS08975
gene id: 1196094:SALWKB2_RS08975
uniprot id: X2H721
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1196094:SALWKB2 RS04955
gene id: 1196094:SALWKB2_RS04955
uniprot id: X2HAZ9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1196094:SALWKB2 RS09070
gene id: 1196094:SALWKB2_RS09070
uniprot id: X2HDM8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1196094:SALWKB2 RS09990
gene id: 1196094:SALWKB2_RS09990
uniprot id: X2HE19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urea transporter family.
messages: Cell membrane
messages: Membrane

1196094:SALWKB2 RS07985
gene id: 1196094:SALWKB2_RS07985
uniprot id: X2HHB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1196094:SALWKB2 RS07225
gene id: 1196094:SALWKB2_RS07225
uniprot id: X2HC79
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS03050
gene id: 1196094:SALWKB2_RS03050
uniprot id: X2H696
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

1196094:SALWKB2 RS05695
gene id: 1196094:SALWKB2_RS05695
uniprot id: X2H7W8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

1196094:SALWKB2 RS01950
gene id: 1196094:SALWKB2_RS01950
uniprot id: X2H9I7
names: Similarity
messages: Belongs to the MQO family.

1196094:SALWKB2 RS08430
gene id: 1196094:SALWKB2_RS08430
uniprot id: X2H6N7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1196094:SALWKB2 RS07175
gene id: 1196094:SALWKB2_RS07175
uniprot id: X2HCK7
names: Similarity
messages: Belongs to the catalase family.

1196094:SALWKB2 RS08265
gene id: 1196094:SALWKB2_RS08265
uniprot id: X2H9G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1196094:SALWKB2 RS06480
gene id: 1196094:SALWKB2_RS06480
uniprot id: X2HCA2
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1196094:SALWKB2 RS05135
gene id: 1196094:SALWKB2_RS05135
uniprot id: X2H4Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1196094:SALWKB2 RS05230
gene id: 1196094:SALWKB2_RS05230
uniprot id: X2HBE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1196094:SALWKB2 RS06125
gene id: 1196094:SALWKB2_RS06125
uniprot id: X2HBP0
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1196094:SALWKB2 RS07905
gene id: 1196094:SALWKB2_RS07905
uniprot id: X2HCZ5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1196094:SALWKB2 RS10375
gene id: 1196094:SALWKB2_RS10375
uniprot id: X2HE90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1196094:SALWKB2 RS04145
gene id: 1196094:SALWKB2_RS04145
uniprot id: X2HAV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1196094:SALWKB2 RS05930
gene id: 1196094:SALWKB2_RS05930
uniprot id: X2H580
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

1196094:SALWKB2 RS00795
gene id: 1196094:SALWKB2_RS00795
uniprot id: X2H510
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1196094:SALWKB2 RS10725
gene id: 1196094:SALWKB2_RS10725
uniprot id: X2HEG9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1196094:SALWKB2 RS01530
gene id: 1196094:SALWKB2_RS01530
uniprot id: X2H9C1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA-dependent ATPase and 5'-3' DNA helicase.

1196094:SALWKB2 RS11415
gene id: 1196094:SALWKB2_RS11415
uniprot id: X2HJJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

1196094:SALWKB2 RS11495
gene id: 1196094:SALWKB2_RS11495
uniprot id: X2HCX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1196094:SALWKB2 RS07040
gene id: 1196094:SALWKB2_RS07040
uniprot id: X2HCI8
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1196094:SALWKB2 RS09880
gene id: 1196094:SALWKB2_RS09880
uniprot id: X2HAC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1196094:SALWKB2 RS03460
gene id: 1196094:SALWKB2_RS03460
uniprot id: X2H3T9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1196094:SALWKB2 RS10005
gene id: 1196094:SALWKB2_RS10005
uniprot id: X2HIH5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1196094:SALWKB2 RS04340
gene id: 1196094:SALWKB2_RS04340
uniprot id: X2HAY4
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

1196094:SALWKB2 RS07230
gene id: 1196094:SALWKB2_RS07230
uniprot id: X2H5Z2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1196094:SALWKB2 RS08475
gene id: 1196094:SALWKB2_RS08475
uniprot id: X2HD24
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1196094:SALWKB2 RS08180
gene id: 1196094:SALWKB2_RS08180
uniprot id: X2HD55
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

1196094:SALWKB2 RS05680
gene id: 1196094:SALWKB2_RS05680
uniprot id: X2HBQ6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1196094:SALWKB2 RS02840
gene id: 1196094:SALWKB2_RS02840
uniprot id: X2HA05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

1196094:SALWKB2 RS07090
gene id: 1196094:SALWKB2_RS07090
uniprot id: X2H8S9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1196094:SALWKB2 RS11430
gene id: 1196094:SALWKB2_RS11430
uniprot id: X2H8F0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1196094:SALWKB2 RS09995
gene id: 1196094:SALWKB2_RS09995
uniprot id: X2H7H8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1196094:SALWKB2 RS01050
gene id: 1196094:SALWKB2_RS01050
uniprot id: X2H2I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1196094:SALWKB2 RS04005
gene id: 1196094:SALWKB2_RS04005
uniprot id: X2H481
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS03375
gene id: 1196094:SALWKB2_RS03375
uniprot id: X2HAC5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1196094:SALWKB2 RS06840
gene id: 1196094:SALWKB2_RS06840
uniprot id: X2H5S3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1196094:SALWKB2 RS01845
gene id: 1196094:SALWKB2_RS01845
uniprot id: X2H5M3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

1196094:SALWKB2 RS10870
gene id: 1196094:SALWKB2_RS10870
uniprot id: X2HJ13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1196094:SALWKB2 RS06795
gene id: 1196094:SALWKB2_RS06795
uniprot id: X2H8N0
names: Similarity
messages: Belongs to the NAD synthetase family.

1196094:SALWKB2 RS06115
gene id: 1196094:SALWKB2_RS06115
uniprot id: X2HGA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1196094:SALWKB2 RS06940
gene id: 1196094:SALWKB2_RS06940
uniprot id: X2H5U0
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1196094:SALWKB2 RS02270
gene id: 1196094:SALWKB2_RS02270
uniprot id: X2HE28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1196094:SALWKB2 RS08135
gene id: 1196094:SALWKB2_RS08135
uniprot id: X2HD47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1196094:SALWKB2 RS01765
gene id: 1196094:SALWKB2_RS01765
uniprot id: X2H2X7
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS06130
gene id: 1196094:SALWKB2_RS06130
uniprot id: X2H5D0
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

1196094:SALWKB2 RS04235
gene id: 1196094:SALWKB2_RS04235
uniprot id: X2HF86
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1196094:SALWKB2 RS05395
gene id: 1196094:SALWKB2_RS05395
uniprot id: X2H7P0
names: Similarity
messages: Belongs to the UPF0758 family.

1196094:SALWKB2 RS05720
gene id: 1196094:SALWKB2_RS05720
uniprot id: X2HG09
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
messages: Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).

1196094:SALWKB2 RS08090
gene id: 1196094:SALWKB2_RS08090
uniprot id: X2HD39
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1196094:SALWKB2 RS06055
gene id: 1196094:SALWKB2_RS06055
uniprot id: X2HBM2
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1196094:SALWKB2 RS05215
gene id: 1196094:SALWKB2_RS05215
uniprot id: X2H4R8
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1196094:SALWKB2 RS06205
gene id: 1196094:SALWKB2_RS06205
uniprot id: X2H5F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1196094:SALWKB2 RS05430
gene id: 1196094:SALWKB2_RS05430
uniprot id: X2HB79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1196094:SALWKB2 RS02815
gene id: 1196094:SALWKB2_RS02815
uniprot id: X2H9Z9
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

1196094:SALWKB2 RS04215
gene id: 1196094:SALWKB2_RS04215
uniprot id: X2HF82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1196094:SALWKB2 RS09580
gene id: 1196094:SALWKB2_RS09580
uniprot id: X2HIA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

1196094:SALWKB2 RS04470
gene id: 1196094:SALWKB2_RS04470
uniprot id: X2H4F7
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS01360
gene id: 1196094:SALWKB2_RS01360
uniprot id: X2H927
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1196094:SALWKB2 RS07440
gene id: 1196094:SALWKB2_RS07440
uniprot id: X2HH03
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1196094:SALWKB2 RS10455
gene id: 1196094:SALWKB2_RS10455
uniprot id: X2H7Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1196094:SALWKB2 RS08575
gene id: 1196094:SALWKB2_RS08575
uniprot id: X2HD46
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS05545
gene id: 1196094:SALWKB2_RS05545
uniprot id: X2H4Y2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1196094:SALWKB2 RS01130
gene id: 1196094:SALWKB2_RS01130
uniprot id: X2H936
names: Similarity
messages: Belongs to the RecJ family.

1196094:SALWKB2 RS01665
gene id: 1196094:SALWKB2_RS01665
uniprot id: X2H2W6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1196094:SALWKB2 RS03965
gene id: 1196094:SALWKB2_RS03965
uniprot id: X2H6Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

1196094:SALWKB2 RS01890
gene id: 1196094:SALWKB2_RS01890
uniprot id: X2H2Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1196094:SALWKB2 RS03775
gene id: 1196094:SALWKB2_RS03775
uniprot id: X2HF08
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

1196094:SALWKB2 RS08045
gene id: 1196094:SALWKB2_RS08045
uniprot id: X2HD26
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

1196094:SALWKB2 RS03400
gene id: 1196094:SALWKB2_RS03400
uniprot id: X2HAD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1196094:SALWKB2 RS03735
gene id: 1196094:SALWKB2_RS03735
uniprot id: X2HAE9
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1196094:SALWKB2 RS01040
gene id: 1196094:SALWKB2_RS01040
uniprot id: X2H916
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1196094:SALWKB2 RS04395
gene id: 1196094:SALWKB2_RS04395
uniprot id: X2H762
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

1196094:SALWKB2 RS06220
gene id: 1196094:SALWKB2_RS06220
uniprot id: X2HC40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1196094:SALWKB2 RS09515
gene id: 1196094:SALWKB2_RS09515
uniprot id: X2HI94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

1196094:SALWKB2 RS01335
gene id: 1196094:SALWKB2_RS01335
uniprot id: X2H923
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1196094:SALWKB2 RS06745
gene id: 1196094:SALWKB2_RS06745
uniprot id: X2H8M3
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1196094:SALWKB2 RS00395
gene id: 1196094:SALWKB2_RS00395
uniprot id: X2H243
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1196094:SALWKB2 RS10705
gene id: 1196094:SALWKB2_RS10705
uniprot id: X2HED0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1196094:SALWKB2 RS06605
gene id: 1196094:SALWKB2_RS06605
uniprot id: X2HBY1
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1196094:SALWKB2 RS01865
gene id: 1196094:SALWKB2_RS01865
uniprot id: X2H2Z3
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

1196094:SALWKB2 RS00240
gene id: 1196094:SALWKB2_RS00240
uniprot id: X2HCW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1196094:SALWKB2 RS01255
gene id: 1196094:SALWKB2_RS01255
uniprot id: X2HDL2
names: Similarity
messages: Belongs to the Smg family.

1196094:SALWKB2 RS07435
gene id: 1196094:SALWKB2_RS07435
uniprot id: X2H8Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane

1196094:SALWKB2 RS04455
gene id: 1196094:SALWKB2_RS04455
uniprot id: X2HFC5
names: Subcellular Location Annotation
messages: Cytoplasm

1196094:SALWKB2 RS10330
gene id: 1196094:SALWKB2_RS10330
uniprot id: X2HIP7
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

1196094:SALWKB2 RS04120
gene id: 1196094:SALWKB2_RS04120
uniprot id: X2HAU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1196094:SALWKB2 RS00755
gene id: 1196094:SALWKB2_RS00755
uniprot id: X2H8W1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1196094:SALWKB2 RS03765
gene id: 1196094:SALWKB2_RS03765
uniprot id: X2H441
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

1196094:SALWKB2 RS09250
gene id: 1196094:SALWKB2_RS09250
uniprot id: X2HDR1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1196094:SALWKB2 RS01880
gene id: 1196094:SALWKB2_RS01880
uniprot id: X2H9H6
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1196094:SALWKB2 RS07530
gene id: 1196094:SALWKB2_RS07530
uniprot id: X2HCE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1196094:SALWKB2 RS00100
gene id: 1196094:SALWKB2_RS00100
uniprot id: X2H1Z1
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

1196094:SALWKB2 RS00450
gene id: 1196094:SALWKB2_RS00450
uniprot id: X2H250
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

1196094:SALWKB2 RS10940
gene id: 1196094:SALWKB2_RS10940
uniprot id: X2HB11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

1196094:SALWKB2 RS00545
gene id: 1196094:SALWKB2_RS00545
uniprot id: X2H4W3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

1196094:SALWKB2 RS07120
gene id: 1196094:SALWKB2_RS07120
uniprot id: X2H8T3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1196094:SALWKB2 RS00400
gene id: 1196094:SALWKB2_RS00400
uniprot id: X2H4T8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1196094:SALWKB2 RS06540
gene id: 1196094:SALWKB2_RS06540
uniprot id: X2H8J1
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1196094:SALWKB2 RS08285
gene id: 1196094:SALWKB2_RS08285
uniprot id: X2H9G7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1196094:SALWKB2 RS06265
gene id: 1196094:SALWKB2_RS06265
uniprot id: X2H5I1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

1196094:SALWKB2 RS02225
gene id: 1196094:SALWKB2_RS02225
uniprot id: X2H9P3
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS07155
gene id: 1196094:SALWKB2_RS07155
uniprot id: X2HC62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1196094:SALWKB2 RS03820
gene id: 1196094:SALWKB2_RS03820
uniprot id: X2HF17
names: Similarity
messages: Belongs to the TPP enzyme family.

1196094:SALWKB2 RS05605
gene id: 1196094:SALWKB2_RS05605
uniprot id: X2HFY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1196094:SALWKB2 RS05755
gene id: 1196094:SALWKB2_RS05755
uniprot id: X2HBE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1196094:SALWKB2 RS02055
gene id: 1196094:SALWKB2_RS02055
uniprot id: X2HDZ1
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1196094:SALWKB2 RS05300
gene id: 1196094:SALWKB2_RS05300
uniprot id: X2HFR3
names: Similarity
messages: Belongs to the glutamine synthetase family.

1196094:SALWKB2 RS10735
gene id: 1196094:SALWKB2_RS10735
uniprot id: X2H7X0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1196094:SALWKB2 RS10460
gene id: 1196094:SALWKB2_RS10460
uniprot id: X2HAM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1196094:SALWKB2 RS05585
gene id: 1196094:SALWKB2_RS05585
uniprot id: X2HBN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

1196094:SALWKB2 RS03450
gene id: 1196094:SALWKB2_RS03450
uniprot id: X2HAE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

1196094:SALWKB2 RS05760
gene id: 1196094:SALWKB2_RS05760
uniprot id: X2H533
names: Similarity
messages: Belongs to the UPF0434 family.

1196094:SALWKB2 RS07315
gene id: 1196094:SALWKB2_RS07315
uniprot id: X2HGY1
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS01590
gene id: 1196094:SALWKB2_RS01590
uniprot id: X2HDR3
names: Subunit
messages: Homodimer.

1196094:SALWKB2 RS08445
gene id: 1196094:SALWKB2_RS08445
uniprot id: X2HDA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1196094:SALWKB2 RS06565
gene id: 1196094:SALWKB2_RS06565
uniprot id: X2H8J6
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1196094:SALWKB2 RS08450
gene id: 1196094:SALWKB2_RS08450
uniprot id: X2HD19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1196094:SALWKB2 RS05150
gene id: 1196094:SALWKB2_RS05150
uniprot id: X2HFN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1196094:SALWKB2 RS10510
gene id: 1196094:SALWKB2_RS10510
uniprot id: X2HAP2
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1196094:SALWKB2 RS08460
gene id: 1196094:SALWKB2_RS08460
uniprot id: X2H9L4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

1196094:SALWKB2 RS08835
gene id: 1196094:SALWKB2_RS08835
uniprot id: X2H6Z9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1196094:SALWKB2 RS03075
gene id: 1196094:SALWKB2_RS03075
uniprot id: X2H6A3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1196094:SALWKB2 RS00260
gene id: 1196094:SALWKB2_RS00260
uniprot id: X2H4R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1196094:SALWKB2 RS10385
gene id: 1196094:SALWKB2_RS10385
uniprot id: X2H7P1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1196094:SALWKB2 RS01325
gene id: 1196094:SALWKB2_RS01325
uniprot id: X2HDM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1196094:SALWKB2 RS07915
gene id: 1196094:SALWKB2_RS07915
uniprot id: X2H965
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS11075
gene id: 1196094:SALWKB2_RS11075
uniprot id: X2HJ85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinone-dependent D-lactate dehydrogenase family.
messages: Catalyzes the oxidation of D-lactate to pyruvate.
messages: Cell inner membrane

1196094:SALWKB2 RS04335
gene id: 1196094:SALWKB2_RS04335
uniprot id: X2HFA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1196094:SALWKB2 RS10840
gene id: 1196094:SALWKB2_RS10840
uniprot id: X2HAY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1196094:SALWKB2 RS00025
gene id: 1196094:SALWKB2_RS00025
uniprot id: X2H1X7
names: Similarity
messages: Belongs to the IMPACT family.

1196094:SALWKB2 RS05035
gene id: 1196094:SALWKB2_RS05035
uniprot id: X2H4P3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1196094:SALWKB2 RS04870
gene id: 1196094:SALWKB2_RS04870
uniprot id: X2HFJ0
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1196094:SALWKB2 RS05830
gene id: 1196094:SALWKB2_RS05830
uniprot id: X2HBG8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1196094:SALWKB2 RS08540
gene id: 1196094:SALWKB2_RS08540
uniprot id: X2HDC7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1196094:SALWKB2 RS05000
gene id: 1196094:SALWKB2_RS05000
uniprot id: X2HB96
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1196094:SALWKB2 RS06100
gene id: 1196094:SALWKB2_RS06100
uniprot id: X2HBN5
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1196094:SALWKB2 RS07055
gene id: 1196094:SALWKB2_RS07055
uniprot id: X2H8S0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1196094:SALWKB2 RS06960
gene id: 1196094:SALWKB2_RS06960
uniprot id: X2HC35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1196094:SALWKB2 RS01670
gene id: 1196094:SALWKB2_RS01670
uniprot id: X2H5J6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1196094:SALWKB2 RS07585
gene id: 1196094:SALWKB2_RS07585
uniprot id: X2H646
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1196094:SALWKB2 RS08255
gene id: 1196094:SALWKB2_RS08255
uniprot id: X2HCX2
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1196094:SALWKB2 RS03265
gene id: 1196094:SALWKB2_RS03265
uniprot id: X2HEL9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1196094:SALWKB2 RS07500
gene id: 1196094:SALWKB2_RS07500
uniprot id: X2HCD9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1196094:SALWKB2 RS05260
gene id: 1196094:SALWKB2_RS05260
uniprot id: X2HB50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1196094:SALWKB2 RS06705
gene id: 1196094:SALWKB2_RS06705
uniprot id: X2HCD8
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS07360
gene id: 1196094:SALWKB2_RS07360
uniprot id: X2H8W9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1196094:SALWKB2 RS09955
gene id: 1196094:SALWKB2_RS09955
uniprot id: X2HE10
names: Subunit
messages: Homodimer.

1196094:SALWKB2 RS03010
gene id: 1196094:SALWKB2_RS03010
uniprot id: X2HA44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1196094:SALWKB2 RS05590
gene id: 1196094:SALWKB2_RS05590
uniprot id: X2HBA4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1196094:SALWKB2 RS10595
gene id: 1196094:SALWKB2_RS10595
uniprot id: X2HIU8
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1196094:SALWKB2 RS01330
gene id: 1196094:SALWKB2_RS01330
uniprot id: X2H993
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1196094:SALWKB2 RS05315
gene id: 1196094:SALWKB2_RS05315
uniprot id: X2H4T6
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1196094:SALWKB2 RS09020
gene id: 1196094:SALWKB2_RS09020
uniprot id: X2HDM0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1196094:SALWKB2 RS10820
gene id: 1196094:SALWKB2_RS10820
uniprot id: X2HIZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1196094:SALWKB2 RS05010
gene id: 1196094:SALWKB2_RS05010
uniprot id: X2H4N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

1196094:SALWKB2 RS03475
gene id: 1196094:SALWKB2_RS03475
uniprot id: X2HA84
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1196094:SALWKB2 RS03170
gene id: 1196094:SALWKB2_RS03170
uniprot id: X2H6D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

1196094:SALWKB2 RS06620
gene id: 1196094:SALWKB2_RS06620
uniprot id: X2HCC6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1196094:SALWKB2 RS07150
gene id: 1196094:SALWKB2_RS07150
uniprot id: X2HCK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1196094:SALWKB2 RS11180
gene id: 1196094:SALWKB2_RS11180
uniprot id: X2HES2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1196094:SALWKB2 RS11115
gene id: 1196094:SALWKB2_RS11115
uniprot id: X2HB58
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1196094:SALWKB2 RS07305
gene id: 1196094:SALWKB2_RS07305
uniprot id: X2H600
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1196094:SALWKB2 RS01185
gene id: 1196094:SALWKB2_RS01185
uniprot id: X2H5A2
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1196094:SALWKB2 RS11450
gene id: 1196094:SALWKB2_RS11450
uniprot id: X2HEW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

1196094:SALWKB2 RS09080
gene id: 1196094:SALWKB2_RS09080
uniprot id: X2H736
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1196094:SALWKB2 RS10790
gene id: 1196094:SALWKB2_RS10790
uniprot id: X2HAX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1196094:SALWKB2 RS10520
gene id: 1196094:SALWKB2_RS10520
uniprot id: X2H7S1
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

1196094:SALWKB2 RS00340
gene id: 1196094:SALWKB2_RS00340
uniprot id: X2H8G2
names: Subcellular Location Annotation
messages: Membrane

1196094:SALWKB2 RS10740
gene id: 1196094:SALWKB2_RS10740
uniprot id: X2HAW1
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1196094:SALWKB2 RS03935
gene id: 1196094:SALWKB2_RS03935
uniprot id: X2HAJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1196094:SALWKB2 RS02500
gene id: 1196094:SALWKB2_RS02500
uniprot id: X2H9L8
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

1196094:SALWKB2 RS00970
gene id: 1196094:SALWKB2_RS00970
uniprot id: X2H542
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1196094:SALWKB2 RS02785
gene id: 1196094:SALWKB2_RS02785
uniprot id: X2HEB5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1196094:SALWKB2 RS03455
gene id: 1196094:SALWKB2_RS03455
uniprot id: X2HA78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

1196094:SALWKB2 RS03710
gene id: 1196094:SALWKB2_RS03710
uniprot id: X2HAE2
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1196094:SALWKB2 RS11330
gene id: 1196094:SALWKB2_RS11330
uniprot id: X2HBC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1196094:SALWKB2 RS00105
gene id: 1196094:SALWKB2_RS00105
uniprot id: X2H4N6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

1196094:SALWKB2 RS07480
gene id: 1196094:SALWKB2_RS07480
uniprot id: X2H629
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1196094:SALWKB2 RS08690
gene id: 1196094:SALWKB2_RS08690
uniprot id: X2HHV8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1196094:SALWKB2 RS10200
gene id: 1196094:SALWKB2_RS10200
uniprot id: X2HAH1
names: Cofactor
messages: Binds 1 phosphopantetheine covalently.

1196094:SALWKB2 RS01125
gene id: 1196094:SALWKB2_RS01125
uniprot id: X2HDG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

1196094:SALWKB2 RS03830
gene id: 1196094:SALWKB2_RS03830
uniprot id: X2HAH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

1196094:SALWKB2 RS05050
gene id: 1196094:SALWKB2_RS05050
uniprot id: X2HBA8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1196094:SALWKB2 RS04285
gene id: 1196094:SALWKB2_RS04285
uniprot id: X2HF94
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1196094:SALWKB2 RS00165
gene id: 1196094:SALWKB2_RS00165
uniprot id: X2H8K3
names: Similarity
messages: Belongs to the SCO1/2 family.

1196094:SALWKB2 RS11030
gene id: 1196094:SALWKB2_RS11030
uniprot id: X2HB37
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1196094:SALWKB2 RS10710
gene id: 1196094:SALWKB2_RS10710
uniprot id: X2H7W5
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1196094:SALWKB2 RS01430
gene id: 1196094:SALWKB2_RS01430
uniprot id: X2HDP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1196094:SALWKB2 RS04910
gene id: 1196094:SALWKB2_RS04910
uniprot id: X2H4M1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1196094:SALWKB2 RS05500
gene id: 1196094:SALWKB2_RS05500
uniprot id: X2HFV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1196094:SALWKB2 RS00150
gene id: 1196094:SALWKB2_RS00150
uniprot id: X2H200
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1196094:SALWKB2 RS05620
gene id: 1196094:SALWKB2_RS05620
uniprot id: X2H500
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

1196094:SALWKB2 RS05805
gene id: 1196094:SALWKB2_RS05805
uniprot id: X2HBG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1196094:SALWKB2 RS06710
gene id: 1196094:SALWKB2_RS06710
uniprot id: X2HBZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1196094:SALWKB2 RS06735
gene id: 1196094:SALWKB2_RS06735
uniprot id: X2HC01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0761 family.
messages: Cell membrane
messages: Membrane

1196094:SALWKB2 RS07550
gene id: 1196094:SALWKB2_RS07550
uniprot id: X2HCR9
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

1196094:SALWKB2 RS03150
gene id: 1196094:SALWKB2_RS03150
uniprot id: X2HEJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1196094:SALWKB2 RS07335
gene id: 1196094:SALWKB2_RS07335
uniprot id: X2H8W6
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1196094:SALWKB2 RS01340
gene id: 1196094:SALWKB2_RS01340
uniprot id: X2H2S2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1196094:SALWKB2 RS08710
gene id: 1196094:SALWKB2_RS08710
uniprot id: X2H9S5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1196094:SALWKB2 RS02795
gene id: 1196094:SALWKB2_RS02795
uniprot id: X2H9R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

1196094:SALWKB2 RS10905
gene id: 1196094:SALWKB2_RS10905
uniprot id: X2HEI4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1196094:SALWKB2 RS09645
gene id: 1196094:SALWKB2_RS09645
uniprot id: X2HIB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiU subfamily.
messages: Forms an heterodimer with UbiV.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiV, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

1196094:SALWKB2 RS05520
gene id: 1196094:SALWKB2_RS05520
uniprot id: X2H4X7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1196094:SALWKB2 RS10445
gene id: 1196094:SALWKB2_RS10445
uniprot id: X2HEA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1196094:SALWKB2 RS00760
gene id: 1196094:SALWKB2_RS00760
uniprot id: X2H8P9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1196094:SALWKB2 RS10160
gene id: 1196094:SALWKB2_RS10160
uniprot id: X2HE47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1196094:SALWKB2 RS06335
gene id: 1196094:SALWKB2_RS06335
uniprot id: X2HBU7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1196094:SALWKB2 RS00490
gene id: 1196094:SALWKB2_RS00490
uniprot id: X2H8J3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1196094:SALWKB2 RS05965
gene id: 1196094:SALWKB2_RS05965
uniprot id: X2HG65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family.
messages: Cell membrane
messages: Membrane

1196094:SALWKB2 RS04945
gene id: 1196094:SALWKB2_RS04945
uniprot id: X2HFK4
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1196094:SALWKB2 RS10910
gene id: 1196094:SALWKB2_RS10910
uniprot id: X2H820
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1196094:SALWKB2 RS07835
gene id: 1196094:SALWKB2_RS07835
uniprot id: X2HCL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1196094:SALWKB2 RS04075
gene id: 1196094:SALWKB2_RS04075
uniprot id: X2HAK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1196094:SALWKB2 RS06155
gene id: 1196094:SALWKB2_RS06155
uniprot id: X2H5D6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1196094:SALWKB2 RS07115
gene id: 1196094:SALWKB2_RS07115
uniprot id: X2H5W9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1196094:SALWKB2 RS08505
gene id: 1196094:SALWKB2_RS08505
uniprot id: X2H6Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1196094:SALWKB2 RS00935
gene id: 1196094:SALWKB2_RS00935
uniprot id: X2H8T2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1196094:SALWKB2 RS11410
gene id: 1196094:SALWKB2_RS11410
uniprot id: X2HBD2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

1196094:SALWKB2 RS04150
gene id: 1196094:SALWKB2_RS04150
uniprot id: X2HAL7
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1196094:SALWKB2 RS10495
gene id: 1196094:SALWKB2_RS10495
uniprot id: X2HEB8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1196094:SALWKB2 RS10855
gene id: 1196094:SALWKB2_RS10855
uniprot id: X2HEH1
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1196094:SALWKB2 RS10540
gene id: 1196094:SALWKB2_RS10540
uniprot id: X2H7S7
names: Similarity
messages: Belongs to the cytochrome b562 family.