1185653:BBH88 RS04180
gene id: 1185653:BBH88_RS04180
uniprot id: A0A1C7DJX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS01400
gene id: 1185653:BBH88_RS01400
uniprot id: A0A1C7DCU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

1185653:BBH88 RS00250
gene id: 1185653:BBH88_RS00250
uniprot id: A0A1C7DD52
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

1185653:BBH88 RS15550
gene id: 1185653:BBH88_RS15550
uniprot id: A0A1C7DEA5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1185653:BBH88 RS08365
gene id: 1185653:BBH88_RS08365
uniprot id: A0A1C7DIC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1185653:BBH88 RS11700
gene id: 1185653:BBH88_RS11700
uniprot id: A0A1C7DGN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

1185653:BBH88 RS02605
gene id: 1185653:BBH88_RS02605
uniprot id: A0A1C7DBT5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPase class C family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm

1185653:BBH88 RS00125
gene id: 1185653:BBH88_RS00125
uniprot id: A0A1C7DD71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1185653:BBH88 RS12760
gene id: 1185653:BBH88_RS12760
uniprot id: A0A1C7DFR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1185653:BBH88 RS09455
gene id: 1185653:BBH88_RS09455
uniprot id: A0A1C7DHV7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

1185653:BBH88 RS07105
gene id: 1185653:BBH88_RS07105
uniprot id: A0A1C7DIZ6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1185653:BBH88 RS13535
gene id: 1185653:BBH88_RS13535
uniprot id: A0A1C7DFP4
names: Similarity
messages: Belongs to the AHA1 family.

1185653:BBH88 RS14255
gene id: 1185653:BBH88_RS14255
uniprot id: A0A1C7DEY9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

1185653:BBH88 RS17945
gene id: 1185653:BBH88_RS17945
uniprot id: A0A1C7DD57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1185653:BBH88 RS00525
gene id: 1185653:BBH88_RS00525
uniprot id: A0A1C7DCQ5
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1185653:BBH88 RS17955
gene id: 1185653:BBH88_RS17955
uniprot id: A0A1C7DDF3
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

1185653:BBH88 RS16095
gene id: 1185653:BBH88_RS16095
uniprot id: A0A1C7DES7
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1185653:BBH88 RS15390
gene id: 1185653:BBH88_RS15390
uniprot id: A0A1C7DED7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS15545
gene id: 1185653:BBH88_RS15545
uniprot id: A0A1C7DEA7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1185653:BBH88 RS12005
gene id: 1185653:BBH88_RS12005
uniprot id: A0A1C7DGJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1185653:BBH88 RS06500
gene id: 1185653:BBH88_RS06500
uniprot id: A0A1C7DJD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MenH family.
messages: Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
messages: Monomer.

1185653:BBH88 RS11585
gene id: 1185653:BBH88_RS11585
uniprot id: A0A1C7DGB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1185653:BBH88 RS12980
gene id: 1185653:BBH88_RS12980
uniprot id: A0A1C7DFL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS08760
gene id: 1185653:BBH88_RS08760
uniprot id: A0A1C7DI61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase family. ParE type 2 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1185653:BBH88 RS01745
gene id: 1185653:BBH88_RS01745
uniprot id: A0A1C7DC37
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1185653:BBH88 RS16285
gene id: 1185653:BBH88_RS16285
uniprot id: A0A1C7DE65
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1185653:BBH88 RS07945
gene id: 1185653:BBH88_RS07945
uniprot id: A0A1C7DIJ4
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1185653:BBH88 RS11440
gene id: 1185653:BBH88_RS11440
uniprot id: A0A1C7DGM9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1185653:BBH88 RS07370
gene id: 1185653:BBH88_RS07370
uniprot id: A0A1C7DIU8
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

1185653:BBH88 RS07540
gene id: 1185653:BBH88_RS07540
uniprot id: A0A1C7DIS5
names: Similarity
messages: Belongs to the GSP E family.

1185653:BBH88 RS03395
gene id: 1185653:BBH88_RS03395
uniprot id: A0A1C7DKJ5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS13445
gene id: 1185653:BBH88_RS13445
uniprot id: A0A1C7DFM3
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1185653:BBH88 RS18375
gene id: 1185653:BBH88_RS18375
uniprot id: A0A1C7DD72
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1185653:BBH88 RS11760
gene id: 1185653:BBH88_RS11760
uniprot id: A0A1C7DGM7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1185653:BBH88 RS07095
gene id: 1185653:BBH88_RS07095
uniprot id: A0A1C7DIS4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1185653:BBH88 RS09710
gene id: 1185653:BBH88_RS09710
uniprot id: A0A1C7DHQ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1185653:BBH88 RS11995
gene id: 1185653:BBH88_RS11995
uniprot id: A0A1C7DGF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1185653:BBH88 RS00540
gene id: 1185653:BBH88_RS00540
uniprot id: A0A1C7DCY2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1185653:BBH88 RS13335
gene id: 1185653:BBH88_RS13335
uniprot id: A0A1C7DFP1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1185653:BBH88 RS14720
gene id: 1185653:BBH88_RS14720
uniprot id: A0A1C7DFH4
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1185653:BBH88 RS01605
gene id: 1185653:BBH88_RS01605
uniprot id: A0A1C7DCU6
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

1185653:BBH88 RS08475
gene id: 1185653:BBH88_RS08475
uniprot id: A0A1C7DHU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1185653:BBH88 RS02070
gene id: 1185653:BBH88_RS02070
uniprot id: A0A1C7DC03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1185653:BBH88 RS05475
gene id: 1185653:BBH88_RS05475
uniprot id: A0A1C7DL80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm

1185653:BBH88 RS12955
gene id: 1185653:BBH88_RS12955
uniprot id: A0A1C7DFX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS17770
gene id: 1185653:BBH88_RS17770
uniprot id: A0A1C7DDH8
names: Similarity
messages: Belongs to the FGGY kinase family.

1185653:BBH88 RS00755
gene id: 1185653:BBH88_RS00755
uniprot id: A0A1C7DCS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1185653:BBH88 RS13890
gene id: 1185653:BBH88_RS13890
uniprot id: A0A1C7DG20
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1185653:BBH88 RS11790
gene id: 1185653:BBH88_RS11790
uniprot id: A0A1C7DGM5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1185653:BBH88 RS12270
gene id: 1185653:BBH88_RS12270
uniprot id: A0A1C7DGY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. DivIB subfamily.
messages: Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex.
messages: Cell membrane

1185653:BBH88 RS04855
gene id: 1185653:BBH88_RS04855
uniprot id: A0A1C7DK07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS17900
gene id: 1185653:BBH88_RS17900
uniprot id: A0A1C7DDG1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).

1185653:BBH88 RS03040
gene id: 1185653:BBH88_RS03040
uniprot id: A0A1C7DL21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1185653:BBH88 RS12220
gene id: 1185653:BBH88_RS12220
uniprot id: A0A1C7DGZ6
names: Subcellular Location Annotation
messages: Cytoplasm

1185653:BBH88 RS04300
gene id: 1185653:BBH88_RS04300
uniprot id: A0A1C7DKB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS15700
gene id: 1185653:BBH88_RS15700
uniprot id: A0A1C7DF45
names: Similarity
messages: Belongs to the manganese catalase family.

1185653:BBH88 RS00720
gene id: 1185653:BBH88_RS00720
uniprot id: A0A1C7DD64
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1185653:BBH88 RS03515
gene id: 1185653:BBH88_RS03515
uniprot id: A0A1C7DKR3
names: Similarity
messages: Belongs to the transpeptidase family.

1185653:BBH88 RS13875
gene id: 1185653:BBH88_RS13875
uniprot id: A0A1C7DL97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FemABX family.
messages: Cytoplasm

1185653:BBH88 RS04635
gene id: 1185653:BBH88_RS04635
uniprot id: A0A1C7DK47
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1185653:BBH88 RS17215
gene id: 1185653:BBH88_RS17215
uniprot id: A0A1C7DE60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS08205
gene id: 1185653:BBH88_RS08205
uniprot id: A0A1C7DHZ6
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS09245
gene id: 1185653:BBH88_RS09245
uniprot id: A0A1C7DHX6
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1185653:BBH88 RS03965
gene id: 1185653:BBH88_RS03965
uniprot id: A0A1C7DJZ9
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.

1185653:BBH88 RS18210
gene id: 1185653:BBH88_RS18210
uniprot id: A0A1C7DD13
names: Similarity
messages: Belongs to the UPF0758 family.

1185653:BBH88 RS07285
gene id: 1185653:BBH88_RS07285
uniprot id: A0A1C7DII1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1185653:BBH88 RS07665
gene id: 1185653:BBH88_RS07665
uniprot id: A0A1C7DIR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1185653:BBH88 RS01460
gene id: 1185653:BBH88_RS01460
uniprot id: A0A1C7DC89
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1185653:BBH88 RS04345
gene id: 1185653:BBH88_RS04345
uniprot id: A0A1C7DJU2
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1185653:BBH88 RS15955
gene id: 1185653:BBH88_RS15955
uniprot id: A0A1C7DEE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1185653:BBH88 RS04225
gene id: 1185653:BBH88_RS04225
uniprot id: A0A1C7DKR6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1185653:BBH88 RS15115
gene id: 1185653:BBH88_RS15115
uniprot id: A0A1C7DEI6
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

1185653:BBH88 RS05200
gene id: 1185653:BBH88_RS05200
uniprot id: A0A1C7DJY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1185653:BBH88 RS03130
gene id: 1185653:BBH88_RS03130
uniprot id: A0A1C7DKN9
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1185653:BBH88 RS07545
gene id: 1185653:BBH88_RS07545
uniprot id: A0A1C7DII6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS08920
gene id: 1185653:BBH88_RS08920
uniprot id: A0A1C7DHP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.

1185653:BBH88 RS01025
gene id: 1185653:BBH88_RS01025
uniprot id: A0A1C7DD65
names: Similarity
messages: Belongs to the AHA1 family.

1185653:BBH88 RS04365
gene id: 1185653:BBH88_RS04365
uniprot id: A0A1C7DK11
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1185653:BBH88 RS12440
gene id: 1185653:BBH88_RS12440
uniprot id: A0A1C7DFW5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Interacts with CtaA.
messages: Membrane

1185653:BBH88 RS11225
gene id: 1185653:BBH88_RS11225
uniprot id: A0A1C7DGZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1185653:BBH88 RS06060
gene id: 1185653:BBH88_RS06060
uniprot id: A0A1C7DJG4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1185653:BBH88 RS07650
gene id: 1185653:BBH88_RS07650
uniprot id: A0A1C7DIK6
names: Similarity
messages: Belongs to the UPF0735 family.

1185653:BBH88 RS13790
gene id: 1185653:BBH88_RS13790
uniprot id: A0A1C7DFK1
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1185653:BBH88 RS07595
gene id: 1185653:BBH88_RS07595
uniprot id: A0A1C7DIH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1185653:BBH88 RS12355
gene id: 1185653:BBH88_RS12355
uniprot id: A0A1C7DGC7
names: Similarity
messages: Belongs to the peptidase S16 family.

1185653:BBH88 RS04355
gene id: 1185653:BBH88_RS04355
uniprot id: A0A1C7DKD2
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS17205
gene id: 1185653:BBH88_RS17205
uniprot id: A0A1C7DEC6
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1185653:BBH88 RS00370
gene id: 1185653:BBH88_RS00370
uniprot id: A0A1C7DD25
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1185653:BBH88 RS13770
gene id: 1185653:BBH88_RS13770
uniprot id: A0A1C7DFC4
names: Similarity
messages: Belongs to the CpsD/CapB family.

1185653:BBH88 RS16445
gene id: 1185653:BBH88_RS16445
uniprot id: A0A1C7DE33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1185653:BBH88 RS14300
gene id: 1185653:BBH88_RS14300
uniprot id: A0A1C7DEX8
names: Similarity
messages: Belongs to the acyltransferase 3 family.

1185653:BBH88 RS03460
gene id: 1185653:BBH88_RS03460
uniprot id: A0A1C7DKS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS01170
gene id: 1185653:BBH88_RS01170
uniprot id: A0A1C7DCK2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

1185653:BBH88 RS08485
gene id: 1185653:BBH88_RS08485
uniprot id: A0A1C7DIA8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1185653:BBH88 RS07450
gene id: 1185653:BBH88_RS07450
uniprot id: A0A1C7DIW0
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1185653:BBH88 RS14695
gene id: 1185653:BBH88_RS14695
uniprot id: A0A1C7DEW3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1185653:BBH88 RS08500
gene id: 1185653:BBH88_RS08500
uniprot id: A0A1C7DI99
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1185653:BBH88 RS15620
gene id: 1185653:BBH88_RS15620
uniprot id: A0A1C7DEL0
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1185653:BBH88 RS14590
gene id: 1185653:BBH88_RS14590
uniprot id: A0A1C7DLC7
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1185653:BBH88 RS12505
gene id: 1185653:BBH88_RS12505
uniprot id: A0A1C7DFV0
names: Similarity
messages: Belongs to the UPF0637 family.

1185653:BBH88 RS13675
gene id: 1185653:BBH88_RS13675
uniprot id: A0A1C7DG59
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1185653:BBH88 RS13305
gene id: 1185653:BBH88_RS13305
uniprot id: A0A1C7DFG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1185653:BBH88 RS05835
gene id: 1185653:BBH88_RS05835
uniprot id: A0A1C7DJH7
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

1185653:BBH88 RS00550
gene id: 1185653:BBH88_RS00550
uniprot id: A0A1C7DCW5
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1185653:BBH88 RS13205
gene id: 1185653:BBH88_RS13205
uniprot id: A0A1C7DFU5
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS00675
gene id: 1185653:BBH88_RS00675
uniprot id: A0A1C7DCM7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1185653:BBH88 RS18390
gene id: 1185653:BBH88_RS18390
uniprot id: A0A1C7DD45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
messages: Cell membrane
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.

1185653:BBH88 RS13080
gene id: 1185653:BBH88_RS13080
uniprot id: A0A1C7DFK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1185653:BBH88 RS07785
gene id: 1185653:BBH88_RS07785
uniprot id: A0A1C7DJ74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

1185653:BBH88 RS11695
gene id: 1185653:BBH88_RS11695
uniprot id: A0A1C7DG94
names: Similarity
messages: Belongs to the CinA family.

1185653:BBH88 RS07180
gene id: 1185653:BBH88_RS07180
uniprot id: A0A1C7DIH9
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1185653:BBH88 RS06760
gene id: 1185653:BBH88_RS06760
uniprot id: A0A1C7DL01
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1185653:BBH88 RS05865
gene id: 1185653:BBH88_RS05865
uniprot id: A0A1C7DJ29
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1185653:BBH88 RS13345
gene id: 1185653:BBH88_RS13345
uniprot id: A0A1C7DFT1
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS15870
gene id: 1185653:BBH88_RS15870
uniprot id: A0A1C7DF12
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1185653:BBH88 RS07295
gene id: 1185653:BBH88_RS07295
uniprot id: A0A1C7DIG0
names: Function
messages: Required for transformation and DNA binding.

1185653:BBH88 RS16910
gene id: 1185653:BBH88_RS16910
uniprot id: A0A1C7DEB9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1185653:BBH88 RS11950
gene id: 1185653:BBH88_RS11950
uniprot id: A0A1C7DGK1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1185653:BBH88 RS14550
gene id: 1185653:BBH88_RS14550
uniprot id: A0A1C7DF67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1185653:BBH88 RS11430
gene id: 1185653:BBH88_RS11430
uniprot id: A0A1C7DGU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1185653:BBH88 RS14330
gene id: 1185653:BBH88_RS14330
uniprot id: A0A1C7DF64
names: Similarity
messages: Belongs to the peptidase S8 family.

1185653:BBH88 RS16865
gene id: 1185653:BBH88_RS16865
uniprot id: A0A1C7DDN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS00030
gene id: 1185653:BBH88_RS00030
uniprot id: A0A1C7DCZ6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1185653:BBH88 RS14605
gene id: 1185653:BBH88_RS14605
uniprot id: A0A1C7DF57
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1185653:BBH88 RS18060
gene id: 1185653:BBH88_RS18060
uniprot id: A0A1C7DDD6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1185653:BBH88 RS01355
gene id: 1185653:BBH88_RS01355
uniprot id: A0A1C7DCA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

1185653:BBH88 RS09845
gene id: 1185653:BBH88_RS09845
uniprot id: A0A1C7DHH2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1185653:BBH88 RS11860
gene id: 1185653:BBH88_RS11860
uniprot id: A0A1C7DGL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1185653:BBH88 RS04085
gene id: 1185653:BBH88_RS04085
uniprot id: A0A1C7DKE7
names: Similarity
messages: Belongs to the aldose epimerase family.

1185653:BBH88 RS15080
gene id: 1185653:BBH88_RS15080
uniprot id: A0A1C7DET1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1185653:BBH88 RS03070
gene id: 1185653:BBH88_RS03070
uniprot id: A0A1C7DKY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1185653:BBH88 RS08330
gene id: 1185653:BBH88_RS08330
uniprot id: A0A1C7DIC8
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1185653:BBH88 RS13355
gene id: 1185653:BBH88_RS13355
uniprot id: A0A1C7DFF0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1185653:BBH88 RS14825
gene id: 1185653:BBH88_RS14825
uniprot id: A0A1C7DF14
names: Similarity
messages: Belongs to the ChdC family. Type 1 subfamily.

1185653:BBH88 RS07040
gene id: 1185653:BBH88_RS07040
uniprot id: A0A1C7DIT2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
messages: Homodimer.

1185653:BBH88 RS06330
gene id: 1185653:BBH88_RS06330
uniprot id: A0A1C7DJE2
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1185653:BBH88 RS06335
gene id: 1185653:BBH88_RS06335
uniprot id: A0A1C7DJQ9
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

1185653:BBH88 RS04075
gene id: 1185653:BBH88_RS04075
uniprot id: A0A1C7DJY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

1185653:BBH88 RS01815
gene id: 1185653:BBH88_RS01815
uniprot id: A0A1C7DC75
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1185653:BBH88 RS11665
gene id: 1185653:BBH88_RS11665
uniprot id: A0A1C7DGL3
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1185653:BBH88 RS00505
gene id: 1185653:BBH88_RS00505
uniprot id: A0A1C7DCX1
names: Similarity
messages: Belongs to the CtsR family.

1185653:BBH88 RS00340
gene id: 1185653:BBH88_RS00340
uniprot id: A0A1C7DD06
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1185653:BBH88 RS16810
gene id: 1185653:BBH88_RS16810
uniprot id: A0A1C7DDV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS11460
gene id: 1185653:BBH88_RS11460
uniprot id: A0A1C7DGT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS16615
gene id: 1185653:BBH88_RS16615
uniprot id: A0A1C7DE27
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1185653:BBH88 RS16110
gene id: 1185653:BBH88_RS16110
uniprot id: A0A1C7DE98
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DbpA subfamily.
messages: Contains an N-terminal domain that binds non-specifically to RNA and a C-terminal domain that binds specifically and tightly to hairpin 92 of 23S rRNA.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes.

1185653:BBH88 RS17865
gene id: 1185653:BBH88_RS17865
uniprot id: A0A1C7DL57
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS15370
gene id: 1185653:BBH88_RS15370
uniprot id: A0A1C7DFA3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1185653:BBH88 RS08785
gene id: 1185653:BBH88_RS08785
uniprot id: A0A1C7DLE9
names: Similarity
messages: Belongs to the FBPase class 3 family.

1185653:BBH88 RS11935
gene id: 1185653:BBH88_RS11935
uniprot id: A0A1C7DGG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS05180
gene id: 1185653:BBH88_RS05180
uniprot id: A0A1C7DJZ3
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1185653:BBH88 RS12260
gene id: 1185653:BBH88_RS12260
uniprot id: A0A1C7DG83
names: Similarity
messages: Belongs to the UPF0749 family.

1185653:BBH88 RS03590
gene id: 1185653:BBH88_RS03590
uniprot id: A0A1C7DL41
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

1185653:BBH88 RS00215
gene id: 1185653:BBH88_RS00215
uniprot id: A0A1C7DCV1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1185653:BBH88 RS07175
gene id: 1185653:BBH88_RS07175
uniprot id: A0A1C7DIK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1185653:BBH88 RS05885
gene id: 1185653:BBH88_RS05885
uniprot id: A0A1C7DJB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1185653:BBH88 RS02295
gene id: 1185653:BBH88_RS02295
uniprot id: A0A1C7DCH4
names: Subcellular Location Annotation
messages: Cytoplasm

1185653:BBH88 RS12095
gene id: 1185653:BBH88_RS12095
uniprot id: A0A1C7DGC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1185653:BBH88 RS06280
gene id: 1185653:BBH88_RS06280
uniprot id: A0A1C7DJF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS04750
gene id: 1185653:BBH88_RS04750
uniprot id: A0A1C7DK27
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1185653:BBH88 RS09855
gene id: 1185653:BBH88_RS09855
uniprot id: A0A1C7DHK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1185653:BBH88 RS16295
gene id: 1185653:BBH88_RS16295
uniprot id: A0A1C7DET2
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1185653:BBH88 RS12450
gene id: 1185653:BBH88_RS12450
uniprot id: A0A1C7DFV9
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

1185653:BBH88 RS02150
gene id: 1185653:BBH88_RS02150
uniprot id: A0A1C7DBX4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS12940
gene id: 1185653:BBH88_RS12940
uniprot id: A0A1C7DG13
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1185653:BBH88 RS08325
gene id: 1185653:BBH88_RS08325
uniprot id: A0A1C7DI81
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1185653:BBH88 RS07920
gene id: 1185653:BBH88_RS07920
uniprot id: A0A1C7DI49
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1185653:BBH88 RS01465
gene id: 1185653:BBH88_RS01465
uniprot id: A0A1C7DC90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

1185653:BBH88 RS15385
gene id: 1185653:BBH88_RS15385
uniprot id: A0A1C7DED2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS06120
gene id: 1185653:BBH88_RS06120
uniprot id: A0A1C7DK15
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1185653:BBH88 RS07510
gene id: 1185653:BBH88_RS07510
uniprot id: A0A1C7DJ72
names: Function
messages: Required for transformation and DNA binding.

1185653:BBH88 RS09210
gene id: 1185653:BBH88_RS09210
uniprot id: A0A1C7DIH7
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

1185653:BBH88 RS07800
gene id: 1185653:BBH88_RS07800
uniprot id: A0A1C7DJ15
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1185653:BBH88 RS04165
gene id: 1185653:BBH88_RS04165
uniprot id: A0A1C7DKY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS08010
gene id: 1185653:BBH88_RS08010
uniprot id: A0A1C7DIJ8
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1185653:BBH88 RS01125
gene id: 1185653:BBH88_RS01125
uniprot id: A0A1C7DCK7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1185653:BBH88 RS05025
gene id: 1185653:BBH88_RS05025
uniprot id: A0A1C7DJG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS16005
gene id: 1185653:BBH88_RS16005
uniprot id: A0A1C7DE38
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

1185653:BBH88 RS16495
gene id: 1185653:BBH88_RS16495
uniprot id: A0A1C7DE39
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS17530
gene id: 1185653:BBH88_RS17530
uniprot id: A0A1C7DDK0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1185653:BBH88 RS01830
gene id: 1185653:BBH88_RS01830
uniprot id: A0A1C7DLL5
names: Similarity
messages: Belongs to the SCO1/2 family.

1185653:BBH88 RS03295
gene id: 1185653:BBH88_RS03295
uniprot id: A0A1C7DKR9
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1185653:BBH88 RS00285
gene id: 1185653:BBH88_RS00285
uniprot id: A0A1C7DCZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1185653:BBH88 RS15160
gene id: 1185653:BBH88_RS15160
uniprot id: A0A1C7DEG9
names: Subcellular Location Annotation
messages: Cell membrane

1185653:BBH88 RS08310
gene id: 1185653:BBH88_RS08310
uniprot id: A0A1C7DIF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS08260
gene id: 1185653:BBH88_RS08260
uniprot id: A0A1C7DIG4
names: Similarity
messages: Belongs to the Fur family.

1185653:BBH88 RS13195
gene id: 1185653:BBH88_RS13195
uniprot id: A0A1C7DFI0
names: Similarity
messages: Belongs to the IMPACT family.

1185653:BBH88 RS12140
gene id: 1185653:BBH88_RS12140
uniprot id: A0A1C7DG69
names: Similarity
messages: Belongs to the serine/threonine dehydratase family. DsdA subfamily.

1185653:BBH88 RS07715
gene id: 1185653:BBH88_RS07715
uniprot id: A0A1C7DIN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1185653:BBH88 RS00660
gene id: 1185653:BBH88_RS00660
uniprot id: A0A1C7DDC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1185653:BBH88 RS02590
gene id: 1185653:BBH88_RS02590
uniprot id: A0A1C7DBP5
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1185653:BBH88 RS06800
gene id: 1185653:BBH88_RS06800
uniprot id: A0A1C7DJR4
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1185653:BBH88 RS13340
gene id: 1185653:BBH88_RS13340
uniprot id: A0A1C7DGC0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1185653:BBH88 RS04695
gene id: 1185653:BBH88_RS04695
uniprot id: A0A1C7DJV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1185653:BBH88 RS18355
gene id: 1185653:BBH88_RS18355
uniprot id: A0A1C7DCY9
names: Similarity
messages: Belongs to the ParB family.

1185653:BBH88 RS14570
gene id: 1185653:BBH88_RS14570
uniprot id: A0A1C7DF34
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1185653:BBH88 RS09270
gene id: 1185653:BBH88_RS09270
uniprot id: A0A1C7DHY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS03035
gene id: 1185653:BBH88_RS03035
uniprot id: A0A1C7DLJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1185653:BBH88 RS06720
gene id: 1185653:BBH88_RS06720
uniprot id: A0A1C7DJ69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS11915
gene id: 1185653:BBH88_RS11915
uniprot id: A0A1C7DGJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1185653:BBH88 RS10890
gene id: 1185653:BBH88_RS10890
uniprot id: A0A1C7DGY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS14900
gene id: 1185653:BBH88_RS14900
uniprot id: A0A1C7DLR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS14070
gene id: 1185653:BBH88_RS14070
uniprot id: A0A1C7DFU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1185653:BBH88 RS05615
gene id: 1185653:BBH88_RS05615
uniprot id: A0A1C7DJG2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1185653:BBH88 RS03245
gene id: 1185653:BBH88_RS03245
uniprot id: A0A1C7DKS9
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1185653:BBH88 RS00090
gene id: 1185653:BBH88_RS00090
uniprot id: A0A1C7DD50
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1185653:BBH88 RS04220
gene id: 1185653:BBH88_RS04220
uniprot id: A0A1C7DKG4
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS14920
gene id: 1185653:BBH88_RS14920
uniprot id: A0A1C7DEV9
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1185653:BBH88 RS14585
gene id: 1185653:BBH88_RS14585
uniprot id: A0A1C7DF20
names: Similarity
messages: Belongs to the UPF0340 family.

1185653:BBH88 RS11785
gene id: 1185653:BBH88_RS11785
uniprot id: A0A1C7DH84
names: Similarity
messages: Belongs to the ribF family.

1185653:BBH88 RS14545
gene id: 1185653:BBH88_RS14545
uniprot id: A0A1C7DFQ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1185653:BBH88 RS07475
gene id: 1185653:BBH88_RS07475
uniprot id: A0A1C7DIU5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1185653:BBH88 RS01620
gene id: 1185653:BBH88_RS01620
uniprot id: A0A1C7DC60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1185653:BBH88 RS10475
gene id: 1185653:BBH88_RS10475
uniprot id: A0A1C7DHB5
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1185653:BBH88 RS12360
gene id: 1185653:BBH88_RS12360
uniprot id: A0A1C7DG25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1185653:BBH88 RS04125
gene id: 1185653:BBH88_RS04125
uniprot id: A0A1C7DLH5
names: Similarity
messages: Belongs to the PspA/IM30 family.

1185653:BBH88 RS02100
gene id: 1185653:BBH88_RS02100
uniprot id: A0A1C7DBX9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS09990
gene id: 1185653:BBH88_RS09990
uniprot id: A0A1C7DH53
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).

1185653:BBH88 RS07780
gene id: 1185653:BBH88_RS07780
uniprot id: A0A1C7DIM7
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

1185653:BBH88 RS18335
gene id: 1185653:BBH88_RS18335
uniprot id: A0A1C7DL75
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1185653:BBH88 RS04725
gene id: 1185653:BBH88_RS04725
uniprot id: A0A1C7DK73
names: Similarity
messages: Belongs to the CdaR family.

1185653:BBH88 RS07810
gene id: 1185653:BBH88_RS07810
uniprot id: A0A1C7DI87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1185653:BBH88 RS12985
gene id: 1185653:BBH88_RS12985
uniprot id: A0A1C7DFZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS03555
gene id: 1185653:BBH88_RS03555
uniprot id: A0A1C7DKP7
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

1185653:BBH88 RS06355
gene id: 1185653:BBH88_RS06355
uniprot id: A0A1C7DJA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1185653:BBH88 RS13780
gene id: 1185653:BBH88_RS13780
uniprot id: A0A1C7DFG8
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1185653:BBH88 RS12080
gene id: 1185653:BBH88_RS12080
uniprot id: A0A1C7DGH0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1185653:BBH88 RS05920
gene id: 1185653:BBH88_RS05920
uniprot id: A0A1C7DJ20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1185653:BBH88 RS18370
gene id: 1185653:BBH88_RS18370
uniprot id: A0A1C7DD49
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 535 of 16S rRNA.

1185653:BBH88 RS00595
gene id: 1185653:BBH88_RS00595
uniprot id: A0A1C7DCR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1185653:BBH88 RS11625
gene id: 1185653:BBH88_RS11625
uniprot id: A0A1C7DGQ7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

1185653:BBH88 RS02595
gene id: 1185653:BBH88_RS02595
uniprot id: A0A1C7DBP6
names: Similarity
messages: Belongs to the peptidase C56 family.

1185653:BBH88 RS03055
gene id: 1185653:BBH88_RS03055
uniprot id: A0A1C7DKI2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1185653:BBH88 RS04120
gene id: 1185653:BBH88_RS04120
uniprot id: A0A1C7DJY1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1185653:BBH88 RS10030
gene id: 1185653:BBH88_RS10030
uniprot id: A0A1C7DHJ1
names: Similarity
messages: Belongs to the EamA transporter family.

1185653:BBH88 RS12350
gene id: 1185653:BBH88_RS12350
uniprot id: A0A1C7DGB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm

1185653:BBH88 RS02030
gene id: 1185653:BBH88_RS02030
uniprot id: A0A1C7DC48
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1185653:BBH88 RS11690
gene id: 1185653:BBH88_RS11690
uniprot id: A0A1C7DGA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1185653:BBH88 RS11970
gene id: 1185653:BBH88_RS11970
uniprot id: A0A1C7DLC0
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

1185653:BBH88 RS00055
gene id: 1185653:BBH88_RS00055
uniprot id: A0A1C7DD36
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1185653:BBH88 RS13635
gene id: 1185653:BBH88_RS13635
uniprot id: A0A1C7DG27
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

1185653:BBH88 RS16265
gene id: 1185653:BBH88_RS16265
uniprot id: A0A1C7DDZ4
names: Similarity
messages: Belongs to the ThiD family.

1185653:BBH88 RS12925
gene id: 1185653:BBH88_RS12925
uniprot id: A0A1C7DFN9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MecA family.
messages: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
messages: Homodimer.
messages: The N-terminal domain probably binds unfolded/aggregated proteins; the C-terminal domain interacts with ClpC.

1185653:BBH88 RS00975
gene id: 1185653:BBH88_RS00975
uniprot id: A0A1C7DCT9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1185653:BBH88 RS11145
gene id: 1185653:BBH88_RS11145
uniprot id: A0A1C7DHD6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1185653:BBH88 RS07835
gene id: 1185653:BBH88_RS07835
uniprot id: A0A1C7DID2
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1185653:BBH88 RS12050
gene id: 1185653:BBH88_RS12050
uniprot id: A0A1C7DH29
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1185653:BBH88 RS15470
gene id: 1185653:BBH88_RS15470
uniprot id: A0A1C7DF84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1185653:BBH88 RS03585
gene id: 1185653:BBH88_RS03585
uniprot id: A0A1C7DKS8
names: Similarity
messages: Belongs to the glycosyl hydrolase 36 family.

1185653:BBH88 RS03940
gene id: 1185653:BBH88_RS03940
uniprot id: A0A1C7DL28
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the L-aspartate dehydrogenase family.
messages: Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
messages: The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia.

1185653:BBH88 RS14750
gene id: 1185653:BBH88_RS14750
uniprot id: A0A1C7DEZ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1185653:BBH88 RS02265
gene id: 1185653:BBH88_RS02265
uniprot id: A0A1C7DBZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1185653:BBH88 RS08425
gene id: 1185653:BBH88_RS08425
uniprot id: A0A1C7DIB8
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1185653:BBH88 RS16200
gene id: 1185653:BBH88_RS16200
uniprot id: A0A1C7DDZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS05950
gene id: 1185653:BBH88_RS05950
uniprot id: A0A1C7DJI3
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1185653:BBH88 RS14515
gene id: 1185653:BBH88_RS14515
uniprot id: A0A1C7DET9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1185653:BBH88 RS00270
gene id: 1185653:BBH88_RS00270
uniprot id: A0A1C7DCZ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1185653:BBH88 RS15410
gene id: 1185653:BBH88_RS15410
uniprot id: A0A1C7DEM4
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1185653:BBH88 RS07575
gene id: 1185653:BBH88_RS07575
uniprot id: A0A1C7DIC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

1185653:BBH88 RS11955
gene id: 1185653:BBH88_RS11955
uniprot id: A0A1C7DGZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

1185653:BBH88 RS00255
gene id: 1185653:BBH88_RS00255
uniprot id: A0A1C7DDE8
names: Similarity
messages: Belongs to the RutC family.

1185653:BBH88 RS05715
gene id: 1185653:BBH88_RS05715
uniprot id: A0A1C7DJR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.

1185653:BBH88 RS08550
gene id: 1185653:BBH88_RS08550
uniprot id: A0A1C7DI90
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

1185653:BBH88 RS02675
gene id: 1185653:BBH88_RS02675
uniprot id: A0A1C7DBT3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Central regulator of manganese homeostasis.
messages: Cytoplasm
messages: DNA binding is strongly activated by Mn(2+).
messages: Homodimer.

1185653:BBH88 RS04895
gene id: 1185653:BBH88_RS04895
uniprot id: A0A1C7DK08
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1185653:BBH88 RS16375
gene id: 1185653:BBH88_RS16375
uniprot id: A0A1C7DDX6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1185653:BBH88 RS18345
gene id: 1185653:BBH88_RS18345
uniprot id: A0A1C7DDA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1185653:BBH88 RS12100
gene id: 1185653:BBH88_RS12100
uniprot id: A0A1C7DH20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1185653:BBH88 RS09660
gene id: 1185653:BBH88_RS09660
uniprot id: A0A1C7DHG6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1185653:BBH88 RS17440
gene id: 1185653:BBH88_RS17440
uniprot id: A0A1C7DDH6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1185653:BBH88 RS14340
gene id: 1185653:BBH88_RS14340
uniprot id: A0A1C7DFU4
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1185653:BBH88 RS11825
gene id: 1185653:BBH88_RS11825
uniprot id: A0A1C7DGG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1185653:BBH88 RS14645
gene id: 1185653:BBH88_RS14645
uniprot id: A0A1C7DF10
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

1185653:BBH88 RS14365
gene id: 1185653:BBH88_RS14365
uniprot id: A0A1C7DF80
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

1185653:BBH88 RS17960
gene id: 1185653:BBH88_RS17960
uniprot id: A0A1C7DD81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1185653:BBH88 RS00980
gene id: 1185653:BBH88_RS00980
uniprot id: A0A1C7DD23
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

1185653:BBH88 RS00725
gene id: 1185653:BBH88_RS00725
uniprot id: A0A1C7DCL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1185653:BBH88 RS08395
gene id: 1185653:BBH88_RS08395
uniprot id: A0A1C7DID1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

1185653:BBH88 RS11200
gene id: 1185653:BBH88_RS11200
uniprot id: A0A1C7DGZ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1185653:BBH88 RS03265
gene id: 1185653:BBH88_RS03265
uniprot id: A0A1C7DL98
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS14520
gene id: 1185653:BBH88_RS14520
uniprot id: A0A1C7DF49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1185653:BBH88 RS04545
gene id: 1185653:BBH88_RS04545
uniprot id: A0A1C7DK35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS14640
gene id: 1185653:BBH88_RS14640
uniprot id: A0A1C7DEX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1185653:BBH88 RS06655
gene id: 1185653:BBH88_RS06655
uniprot id: A0A1C7DJ00
names: Similarity
messages: Belongs to the PemK/MazF family.

1185653:BBH88 RS11235
gene id: 1185653:BBH88_RS11235
uniprot id: A0A1C7DGS1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1185653:BBH88 RS09440
gene id: 1185653:BBH88_RS09440
uniprot id: A0A1C7DHP4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1185653:BBH88 RS15820
gene id: 1185653:BBH88_RS15820
uniprot id: A0A1C7DEX4
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS06495
gene id: 1185653:BBH88_RS06495
uniprot id: A0A1C7DJW2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

1185653:BBH88 RS06970
gene id: 1185653:BBH88_RS06970
uniprot id: A0A1C7DIN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

1185653:BBH88 RS10615
gene id: 1185653:BBH88_RS10615
uniprot id: A0A1C7DH57
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1185653:BBH88 RS05505
gene id: 1185653:BBH88_RS05505
uniprot id: A0A1C7DJN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family. BdbC subfamily.
messages: Membrane

1185653:BBH88 RS00560
gene id: 1185653:BBH88_RS00560
uniprot id: A0A1C7DDE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

1185653:BBH88 RS12870
gene id: 1185653:BBH88_RS12870
uniprot id: A0A1C7DFP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1185653:BBH88 RS12180
gene id: 1185653:BBH88_RS12180
uniprot id: A0A1C7DLP4
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1185653:BBH88 RS00820
gene id: 1185653:BBH88_RS00820
uniprot id: A0A1C7DD41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1185653:BBH88 RS07385
gene id: 1185653:BBH88_RS07385
uniprot id: A0A1C7DIX0
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1185653:BBH88 RS00825
gene id: 1185653:BBH88_RS00825
uniprot id: A0A1C7DCJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1185653:BBH88 RS14620
gene id: 1185653:BBH88_RS14620
uniprot id: A0A1C7DER9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1185653:BBH88 RS10095
gene id: 1185653:BBH88_RS10095
uniprot id: A0A1C7DHX5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1185653:BBH88 RS07380
gene id: 1185653:BBH88_RS07380
uniprot id: A0A1C7DJF6
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

1185653:BBH88 RS18255
gene id: 1185653:BBH88_RS18255
uniprot id: A0A1C7DD04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS03125
gene id: 1185653:BBH88_RS03125
uniprot id: A0A1C7DKX7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1185653:BBH88 RS14630
gene id: 1185653:BBH88_RS14630
uniprot id: A0A1C7DF26
names: Similarity
messages: Belongs to the FBPase class 2 family.

1185653:BBH88 RS13590
gene id: 1185653:BBH88_RS13590
uniprot id: A0A1C7DFN4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1185653:BBH88 RS07025
gene id: 1185653:BBH88_RS07025
uniprot id: A0A1C7DIK3
names: Similarity
messages: Belongs to the YjdM family.

1185653:BBH88 RS12885
gene id: 1185653:BBH88_RS12885
uniprot id: A0A1C7DG15
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1185653:BBH88 RS12770
gene id: 1185653:BBH88_RS12770
uniprot id: A0A1C7DG33
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1185653:BBH88 RS10505
gene id: 1185653:BBH88_RS10505
uniprot id: A0A1C7DH13
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS14475
gene id: 1185653:BBH88_RS14475
uniprot id: A0A1C7DF73
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1185653:BBH88 RS10590
gene id: 1185653:BBH88_RS10590
uniprot id: A0A1C7DGT6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1185653:BBH88 RS13825
gene id: 1185653:BBH88_RS13825
uniprot id: A0A1C7DFF2
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1185653:BBH88 RS15060
gene id: 1185653:BBH88_RS15060
uniprot id: A0A1C7DEJ4
names: Similarity
messages: Belongs to the EamA transporter family.

1185653:BBH88 RS03015
gene id: 1185653:BBH88_RS03015
uniprot id: A0A1C7DKQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

1185653:BBH88 RS07870
gene id: 1185653:BBH88_RS07870
uniprot id: A0A1C7DI55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

1185653:BBH88 RS16735
gene id: 1185653:BBH88_RS16735
uniprot id: A0A1C7DEK4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1185653:BBH88 RS13485
gene id: 1185653:BBH88_RS13485
uniprot id: A0A1C7DFH9
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS02325
gene id: 1185653:BBH88_RS02325
uniprot id: A0A1C7DC20
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1185653:BBH88 RS16430
gene id: 1185653:BBH88_RS16430
uniprot id: A0A1C7DE40
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

1185653:BBH88 RS06990
gene id: 1185653:BBH88_RS06990
uniprot id: A0A1C7DJ21
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS09695
gene id: 1185653:BBH88_RS09695
uniprot id: A0A1C7DHA7
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1185653:BBH88 RS04175
gene id: 1185653:BBH88_RS04175
uniprot id: A0A1C7DKS6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1185653:BBH88 RS07670
gene id: 1185653:BBH88_RS07670
uniprot id: A0A1C7DJ38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1185653:BBH88 RS08975
gene id: 1185653:BBH88_RS08975
uniprot id: A0A1C7DHN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1185653:BBH88 RS12340
gene id: 1185653:BBH88_RS12340
uniprot id: A0A1C7DFY4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1185653:BBH88 RS06960
gene id: 1185653:BBH88_RS06960
uniprot id: A0A1C7DJ54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EzrA family.
messages: Cell membrane
messages: Membrane
messages: Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization.

1185653:BBH88 RS06165
gene id: 1185653:BBH88_RS06165
uniprot id: A0A1C7DJE4
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS10610
gene id: 1185653:BBH88_RS10610
uniprot id: A0A1C7DH34
names: Caution
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1185653:BBH88 RS11390
gene id: 1185653:BBH88_RS11390
uniprot id: A0A1C7DGN8
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1185653:BBH88 RS02910
gene id: 1185653:BBH88_RS02910
uniprot id: A0A1C7DBV2
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).

1185653:BBH88 RS06160
gene id: 1185653:BBH88_RS06160
uniprot id: A0A1C7DJB3
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1185653:BBH88 RS12000
gene id: 1185653:BBH88_RS12000
uniprot id: A0A1C7DH39
names: Similarity
messages: Belongs to the fabD family.

1185653:BBH88 RS09630
gene id: 1185653:BBH88_RS09630
uniprot id: A0A1C7DHR1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1185653:BBH88 RS00355
gene id: 1185653:BBH88_RS00355
uniprot id: A0A1C7DLM3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1185653:BBH88 RS11865
gene id: 1185653:BBH88_RS11865
uniprot id: A0A1C7DGK5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1185653:BBH88 RS16365
gene id: 1185653:BBH88_RS16365
uniprot id: A0A1C7DL62
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS01720
gene id: 1185653:BBH88_RS01720
uniprot id: A0A1C7DC95
names: Similarity
messages: Belongs to the peptidase C40 family.

1185653:BBH88 RS05495
gene id: 1185653:BBH88_RS05495
uniprot id: A0A1C7DJR0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1185653:BBH88 RS02870
gene id: 1185653:BBH88_RS02870
uniprot id: A0A1C7DBJ8
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1185653:BBH88 RS00205
gene id: 1185653:BBH88_RS00205
uniprot id: A0A1C7DDF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1185653:BBH88 RS08495
gene id: 1185653:BBH88_RS08495
uniprot id: A0A1C7DI50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1185653:BBH88 RS14660
gene id: 1185653:BBH88_RS14660
uniprot id: A0A1C7DKY4
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

1185653:BBH88 RS13480
gene id: 1185653:BBH88_RS13480
uniprot id: A0A1C7DFQ3
names: Similarity
messages: Belongs to the CpsD/CapB family.

1185653:BBH88 RS12255
gene id: 1185653:BBH88_RS12255
uniprot id: A0A1C7DG50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

1185653:BBH88 RS08750
gene id: 1185653:BBH88_RS08750
uniprot id: A0A1C7DI70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1185653:BBH88 RS13000
gene id: 1185653:BBH88_RS13000
uniprot id: A0A1C7DFV6
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1185653:BBH88 RS17935
gene id: 1185653:BBH88_RS17935
uniprot id: A0A1C7DDT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1185653:BBH88 RS05005
gene id: 1185653:BBH88_RS05005
uniprot id: A0A1C7DKI7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1185653:BBH88 RS13710
gene id: 1185653:BBH88_RS13710
uniprot id: A0A1C7DL58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1185653:BBH88 RS02275
gene id: 1185653:BBH88_RS02275
uniprot id: A0A1C7DBW2
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS14690
gene id: 1185653:BBH88_RS14690
uniprot id: A0A1C7DF40
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1185653:BBH88 RS14250
gene id: 1185653:BBH88_RS14250
uniprot id: A0A1C7DEY6
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1185653:BBH88 RS05190
gene id: 1185653:BBH88_RS05190
uniprot id: A0A1C7DJE9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1185653:BBH88 RS00580
gene id: 1185653:BBH88_RS00580
uniprot id: A0A1C7DCP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1185653:BBH88 RS00790
gene id: 1185653:BBH88_RS00790
uniprot id: A0A1C7DCT3
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1185653:BBH88 RS01630
gene id: 1185653:BBH88_RS01630
uniprot id: A0A1C7DCA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

1185653:BBH88 RS16450
gene id: 1185653:BBH88_RS16450
uniprot id: A0A1C7DE26
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1185653:BBH88 RS04425
gene id: 1185653:BBH88_RS04425
uniprot id: A0A1C7DK55
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS14635
gene id: 1185653:BBH88_RS14635
uniprot id: A0A1C7DF44
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1185653:BBH88 RS13390
gene id: 1185653:BBH88_RS13390
uniprot id: A0A1C7DFN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

1185653:BBH88 RS15215
gene id: 1185653:BBH88_RS15215
uniprot id: A0A1C7DEU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1185653:BBH88 RS09055
gene id: 1185653:BBH88_RS09055
uniprot id: A0A1C7DHR3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1185653:BBH88 RS12275
gene id: 1185653:BBH88_RS12275
uniprot id: A0A1C7DGE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1185653:BBH88 RS14500
gene id: 1185653:BBH88_RS14500
uniprot id: A0A1C7DF77
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1185653:BBH88 RS16195
gene id: 1185653:BBH88_RS16195
uniprot id: A0A1C7DEQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Membrane

1185653:BBH88 RS07055
gene id: 1185653:BBH88_RS07055
uniprot id: A0A1C7DJL6
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1185653:BBH88 RS11930
gene id: 1185653:BBH88_RS11930
uniprot id: A0A1C7DGE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

1185653:BBH88 RS00070
gene id: 1185653:BBH88_RS00070
uniprot id: A0A1C7DDI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

1185653:BBH88 RS07950
gene id: 1185653:BBH88_RS07950
uniprot id: A0A1C7DJ43
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1185653:BBH88 RS12090
gene id: 1185653:BBH88_RS12090
uniprot id: A0A1C7DGB3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1185653:BBH88 RS06130
gene id: 1185653:BBH88_RS06130
uniprot id: A0A1C7DJU9
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1185653:BBH88 RS12425
gene id: 1185653:BBH88_RS12425
uniprot id: A0A1C7DGV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS11085
gene id: 1185653:BBH88_RS11085
uniprot id: A0A1C7DHL7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1185653:BBH88 RS05980
gene id: 1185653:BBH88_RS05980
uniprot id: A0A1C7DJH1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1185653:BBH88 RS12295
gene id: 1185653:BBH88_RS12295
uniprot id: A0A1C7DGC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1185653:BBH88 RS06255
gene id: 1185653:BBH88_RS06255
uniprot id: A0A1C7DJC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS00700
gene id: 1185653:BBH88_RS00700
uniprot id: A0A1C7DCT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1185653:BBH88 RS10515
gene id: 1185653:BBH88_RS10515
uniprot id: A0A1C7DH75
names: Subcellular Location Annotation
messages: Cytoplasm

1185653:BBH88 RS15065
gene id: 1185653:BBH88_RS15065
uniprot id: A0A1C7DEU2
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS10005
gene id: 1185653:BBH88_RS10005
uniprot id: A0A1C7DHJ8
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1185653:BBH88 RS04930
gene id: 1185653:BBH88_RS04930
uniprot id: A0A1C7DJZ2
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1185653:BBH88 RS16655
gene id: 1185653:BBH88_RS16655
uniprot id: A0A1C7DDS0
names: Similarity
messages: Belongs to the HPS/KGPDC family. HPS subfamily.

1185653:BBH88 RS00960
gene id: 1185653:BBH88_RS00960
uniprot id: A0A1C7DCP2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1185653:BBH88 RS14830
gene id: 1185653:BBH88_RS14830
uniprot id: A0A1C7DFF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1185653:BBH88 RS05775
gene id: 1185653:BBH88_RS05775
uniprot id: A0A1C7DJD3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1185653:BBH88 RS17880
gene id: 1185653:BBH88_RS17880
uniprot id: A0A1C7DDU4
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1185653:BBH88 RS10335
gene id: 1185653:BBH88_RS10335
uniprot id: A0A1C7DHD7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1185653:BBH88 RS16145
gene id: 1185653:BBH88_RS16145
uniprot id: A0A1C7DER7
names: Similarity
messages: Belongs to the glutamate synthase family.

1185653:BBH88 RS11795
gene id: 1185653:BBH88_RS11795
uniprot id: A0A1C7DH19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1185653:BBH88 RS03480
gene id: 1185653:BBH88_RS03480
uniprot id: A0A1C7DKA1
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1185653:BBH88 RS07850
gene id: 1185653:BBH88_RS07850
uniprot id: A0A1C7DJ65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1185653:BBH88 RS14385
gene id: 1185653:BBH88_RS14385
uniprot id: A0A1C7DF54
names: Similarity
messages: Belongs to the peptidase C40 family.

1185653:BBH88 RS06980
gene id: 1185653:BBH88_RS06980
uniprot id: A0A1C7DIL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1185653:BBH88 RS14075
gene id: 1185653:BBH88_RS14075
uniprot id: A0A1C7DF13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1185653:BBH88 RS00320
gene id: 1185653:BBH88_RS00320
uniprot id: A0A1C7DCS2
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1185653:BBH88 RS06285
gene id: 1185653:BBH88_RS06285
uniprot id: A0A1C7DJS1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS07100
gene id: 1185653:BBH88_RS07100
uniprot id: A0A1C7DIW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1185653:BBH88 RS00955
gene id: 1185653:BBH88_RS00955
uniprot id: A0A1C7DCK6
names: Similarity
messages: Belongs to the citrate synthase family.

1185653:BBH88 RS15935
gene id: 1185653:BBH88_RS15935
uniprot id: A0A1C7DEV7
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS13720
gene id: 1185653:BBH88_RS13720
uniprot id: A0A1C7DFH1
names: Similarity
messages: Belongs to the YciI family.

1185653:BBH88 RS06945
gene id: 1185653:BBH88_RS06945
uniprot id: A0A1C7DIZ3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family. L-methionine gamma-lyase subfamily.

1185653:BBH88 RS17505
gene id: 1185653:BBH88_RS17505
uniprot id: A0A1C7DE52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1185653:BBH88 RS03285
gene id: 1185653:BBH88_RS03285
uniprot id: A0A1C7DKU9
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS10635
gene id: 1185653:BBH88_RS10635
uniprot id: A0A1C7DGT5
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

1185653:BBH88 RS04850
gene id: 1185653:BBH88_RS04850
uniprot id: A0A1C7DLJ3
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1185653:BBH88 RS18380
gene id: 1185653:BBH88_RS18380
uniprot id: A0A1C7DD01
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1185653:BBH88 RS11205
gene id: 1185653:BBH88_RS11205
uniprot id: A0A1C7DHC3
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

1185653:BBH88 RS05290
gene id: 1185653:BBH88_RS05290
uniprot id: A0A1C7DK83
names: Similarity
messages: Belongs to the Fur family.

1185653:BBH88 RS10345
gene id: 1185653:BBH88_RS10345
uniprot id: A0A1C7DH80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS02220
gene id: 1185653:BBH88_RS02220
uniprot id: A0A1C7DC42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1185653:BBH88 RS00635
gene id: 1185653:BBH88_RS00635
uniprot id: A0A1C7DCU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1185653:BBH88 RS01545
gene id: 1185653:BBH88_RS01545
uniprot id: A0A1C7DCC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1185653:BBH88 RS04940
gene id: 1185653:BBH88_RS04940
uniprot id: A0A1C7DJW3
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1185653:BBH88 RS10290
gene id: 1185653:BBH88_RS10290
uniprot id: A0A1C7DH91
names: Function
names: Similarity
messages: Belongs to the peptidase S33 family.
messages: Releases the N-terminal proline from various substrates.

1185653:BBH88 RS11670
gene id: 1185653:BBH88_RS11670
uniprot id: A0A1C7DHA9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1185653:BBH88 RS03780
gene id: 1185653:BBH88_RS03780
uniprot id: A0A1C7DKH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

1185653:BBH88 RS15610
gene id: 1185653:BBH88_RS15610
uniprot id: A0A1C7DE97
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the NOS family. Bacterial NOS oxygenase subfamily.
messages: Catalyzes the production of nitric oxide.
messages: Homodimer.
messages: This protein is similar to the oxygenase domain of eukaryotic nitric oxide synthases but lacks the reductase domain which, in eukaryotes, is responsible for transfer of electrons to the ferric heme during nitric oxide synthesis.

1185653:BBH88 RS00985
gene id: 1185653:BBH88_RS00985
uniprot id: A0A1C7DCI0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1185653:BBH88 RS11280
gene id: 1185653:BBH88_RS11280
uniprot id: A0A1C7DGL9
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1185653:BBH88 RS09205
gene id: 1185653:BBH88_RS09205
uniprot id: A0A1C7DHX3
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1185653:BBH88 RS10160
gene id: 1185653:BBH88_RS10160
uniprot id: A0A1C7DH21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1185653:BBH88 RS05565
gene id: 1185653:BBH88_RS05565
uniprot id: A0A1C7DJQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1185653:BBH88 RS05255
gene id: 1185653:BBH88_RS05255
uniprot id: A0A1C7DJX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS00010
gene id: 1185653:BBH88_RS00010
uniprot id: A0A1C7DCX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1185653:BBH88 RS12300
gene id: 1185653:BBH88_RS12300
uniprot id: A0A1C7DGD4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1185653:BBH88 RS12595
gene id: 1185653:BBH88_RS12595
uniprot id: A0A1C7DG88
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS01715
gene id: 1185653:BBH88_RS01715
uniprot id: A0A1C7DC92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

1185653:BBH88 RS12245
gene id: 1185653:BBH88_RS12245
uniprot id: A0A1C7DGD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1185653:BBH88 RS14310
gene id: 1185653:BBH88_RS14310
uniprot id: A0A1C7DEX9
names: Similarity
messages: Belongs to the peptidase C40 family.

1185653:BBH88 RS12570
gene id: 1185653:BBH88_RS12570
uniprot id: A0A1C7DG82
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Binds 2 Zn(2+) ions per subunit. It is not clear if Zn(2+) or Mg(2+) is physiologically important.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1185653:BBH88 RS03775
gene id: 1185653:BBH88_RS03775
uniprot id: A0A1C7DKC0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1185653:BBH88 RS06510
gene id: 1185653:BBH88_RS06510
uniprot id: A0A1C7DIV9
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.
messages: Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA).

1185653:BBH88 RS15240
gene id: 1185653:BBH88_RS15240
uniprot id: A0A1C7DET7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

1185653:BBH88 RS05545
gene id: 1185653:BBH88_RS05545
uniprot id: A0A1C7DJQ2
names: Similarity
messages: Belongs to the cytochrome P450 family.

1185653:BBH88 RS04405
gene id: 1185653:BBH88_RS04405
uniprot id: A0A1C7DJS4
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS16085
gene id: 1185653:BBH88_RS16085
uniprot id: A0A1C7DEX1
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1185653:BBH88 RS03785
gene id: 1185653:BBH88_RS03785
uniprot id: A0A1C7DKL6
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS12670
gene id: 1185653:BBH88_RS12670
uniprot id: A0A1C7DG66
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS17950
gene id: 1185653:BBH88_RS17950
uniprot id: A0A1C7DDD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1185653:BBH88 RS02735
gene id: 1185653:BBH88_RS02735
uniprot id: A0A1C7DCA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
messages: Cell membrane
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.

1185653:BBH88 RS07050
gene id: 1185653:BBH88_RS07050
uniprot id: A0A1C7DJ06
names: Similarity
messages: Belongs to the universal stress protein A family.

1185653:BBH88 RS06775
gene id: 1185653:BBH88_RS06775
uniprot id: A0A1C7DJ97
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS17485
gene id: 1185653:BBH88_RS17485
uniprot id: A0A1C7DDM8
names: Similarity
messages: Belongs to the IucA/IucC family.

1185653:BBH88 RS02580
gene id: 1185653:BBH88_RS02580
uniprot id: A0A1C7DKX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1185653:BBH88 RS08845
gene id: 1185653:BBH88_RS08845
uniprot id: A0A1C7DIN7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1185653:BBH88 RS15635
gene id: 1185653:BBH88_RS15635
uniprot id: A0A1C7DEH2
names: Similarity
messages: Belongs to the TelA family.

1185653:BBH88 RS06920
gene id: 1185653:BBH88_RS06920
uniprot id: A0A1C7DIP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1185653:BBH88 RS06070
gene id: 1185653:BBH88_RS06070
uniprot id: A0A1C7DK22
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1185653:BBH88 RS05195
gene id: 1185653:BBH88_RS05195
uniprot id: A0A1C7DJD4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1185653:BBH88 RS07410
gene id: 1185653:BBH88_RS07410
uniprot id: A0A1C7DIE4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1185653:BBH88 RS08445
gene id: 1185653:BBH88_RS08445
uniprot id: A0A1C7DLC8
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1185653:BBH88 RS00005
gene id: 1185653:BBH88_RS00005
uniprot id: A0A1C7DDJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1185653:BBH88 RS04960
gene id: 1185653:BBH88_RS04960
uniprot id: A0A1C7DKD8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

1185653:BBH88 RS15430
gene id: 1185653:BBH88_RS15430
uniprot id: A0A1C7DF41
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS01340
gene id: 1185653:BBH88_RS01340
uniprot id: A0A1C7DCZ2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1185653:BBH88 RS05975
gene id: 1185653:BBH88_RS05975
uniprot id: A0A1C7DJ09
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1185653:BBH88 RS01645
gene id: 1185653:BBH88_RS01645
uniprot id: A0A1C7DC73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1185653:BBH88 RS10440
gene id: 1185653:BBH88_RS10440
uniprot id: A0A1C7DHC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS05110
gene id: 1185653:BBH88_RS05110
uniprot id: A0A1C7DJW8
names: Similarity
messages: Belongs to the DinB family.

1185653:BBH88 RS12950
gene id: 1185653:BBH88_RS12950
uniprot id: A0A1C7DFW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS14565
gene id: 1185653:BBH88_RS14565
uniprot id: A0A1C7DES9
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1185653:BBH88 RS03310
gene id: 1185653:BBH88_RS03310
uniprot id: A0A1C7DKX3
names: Similarity
messages: Belongs to the UPF0309 family.

1185653:BBH88 RS12765
gene id: 1185653:BBH88_RS12765
uniprot id: A0A1C7DFQ7
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1185653:BBH88 RS01820
gene id: 1185653:BBH88_RS01820
uniprot id: A0A1C7DCB1
names: Similarity
messages: Belongs to the cycloisomerase 2 family.

1185653:BBH88 RS05720
gene id: 1185653:BBH88_RS05720
uniprot id: A0A1C7DJM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

1185653:BBH88 RS06115
gene id: 1185653:BBH88_RS06115
uniprot id: A0A1C7DJF3
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1185653:BBH88 RS06275
gene id: 1185653:BBH88_RS06275
uniprot id: A0A1C7DJY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS06815
gene id: 1185653:BBH88_RS06815
uniprot id: A0A1C7DIR5
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1185653:BBH88 RS06940
gene id: 1185653:BBH88_RS06940
uniprot id: A0A1C7DIV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1185653:BBH88 RS04305
gene id: 1185653:BBH88_RS04305
uniprot id: A0A1C7DK21
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1185653:BBH88 RS12865
gene id: 1185653:BBH88_RS12865
uniprot id: A0A1C7DGH8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1185653:BBH88 RS15625
gene id: 1185653:BBH88_RS15625
uniprot id: A0A1C7DEF0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1185653:BBH88 RS00155
gene id: 1185653:BBH88_RS00155
uniprot id: A0A1C7DCW0
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1185653:BBH88 RS11215
gene id: 1185653:BBH88_RS11215
uniprot id: A0A1C7DGH7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1185653:BBH88 RS12055
gene id: 1185653:BBH88_RS12055
uniprot id: A0A1C7DGI1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1185653:BBH88 RS06505
gene id: 1185653:BBH88_RS06505
uniprot id: A0A1C7DJQ1
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1185653:BBH88 RS03205
gene id: 1185653:BBH88_RS03205
uniprot id: A0A1C7DM29
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS06185
gene id: 1185653:BBH88_RS06185
uniprot id: A0A1C7DJ01
names: Similarity
messages: Belongs to the HepT RNase toxin family.

1185653:BBH88 RS18300
gene id: 1185653:BBH88_RS18300
uniprot id: A0A1C7DDL3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

1185653:BBH88 RS13855
gene id: 1185653:BBH88_RS13855
uniprot id: A0A1C7DF56
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1185653:BBH88 RS11805
gene id: 1185653:BBH88_RS11805
uniprot id: A0A1C7DG75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1185653:BBH88 RS05700
gene id: 1185653:BBH88_RS05700
uniprot id: A0A1C7DK36
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS07170
gene id: 1185653:BBH88_RS07170
uniprot id: A0A1C7DJD7
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Monomer.

1185653:BBH88 RS06260
gene id: 1185653:BBH88_RS06260
uniprot id: A0A1C7DJ49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS07445
gene id: 1185653:BBH88_RS07445
uniprot id: A0A1C7DJE6
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1185653:BBH88 RS09715
gene id: 1185653:BBH88_RS09715
uniprot id: A0A1C7DHF3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1185653:BBH88 RS12040
gene id: 1185653:BBH88_RS12040
uniprot id: A0A1C7DGC5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1185653:BBH88 RS15770
gene id: 1185653:BBH88_RS15770
uniprot id: A0A1C7DE75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

1185653:BBH88 RS11415
gene id: 1185653:BBH88_RS11415
uniprot id: A0A1C7DGF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1185653:BBH88 RS13405
gene id: 1185653:BBH88_RS13405
uniprot id: A0A1C7DFS0
names: Subcellular Location Annotation
messages: Cell membrane

1185653:BBH88 RS13665
gene id: 1185653:BBH88_RS13665
uniprot id: A0A1C7DFI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1185653:BBH88 RS02860
gene id: 1185653:BBH88_RS02860
uniprot id: A0A1C7DBV9
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS00020
gene id: 1185653:BBH88_RS00020
uniprot id: A0A1C7DD40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1185653:BBH88 RS00390
gene id: 1185653:BBH88_RS00390
uniprot id: A0A1C7DCX2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1185653:BBH88 RS11905
gene id: 1185653:BBH88_RS11905
uniprot id: A0A1C7DG65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1185653:BBH88 RS14960
gene id: 1185653:BBH88_RS14960
uniprot id: A0A1C7DEY7
names: Caution
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1185653:BBH88 RS08020
gene id: 1185653:BBH88_RS08020
uniprot id: A0A1C7DI45
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1185653:BBH88 RS06735
gene id: 1185653:BBH88_RS06735
uniprot id: A0A1C7DJ64
names: Similarity
messages: Belongs to the universal stress protein A family.

1185653:BBH88 RS01750
gene id: 1185653:BBH88_RS01750
uniprot id: A0A1C7DC85
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1185653:BBH88 RS05135
gene id: 1185653:BBH88_RS05135
uniprot id: A0A1C7DJE0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

1185653:BBH88 RS13695
gene id: 1185653:BBH88_RS13695
uniprot id: A0A1C7DF85
names: Similarity
messages: Belongs to the threonine aldolase family.

1185653:BBH88 RS04020
gene id: 1185653:BBH88_RS04020
uniprot id: A0A1C7DJZ1
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS15855
gene id: 1185653:BBH88_RS15855
uniprot id: A0A1C7DEB3
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1185653:BBH88 RS18225
gene id: 1185653:BBH88_RS18225
uniprot id: A0A1C7DD29
names: Similarity
messages: Belongs to the HsdR family.

1185653:BBH88 RS15225
gene id: 1185653:BBH88_RS15225
uniprot id: A0A1C7DEF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS02465
gene id: 1185653:BBH88_RS02465
uniprot id: A0A1C7DBR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1185653:BBH88 RS01105
gene id: 1185653:BBH88_RS01105
uniprot id: A0A1C7DCN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1185653:BBH88 RS07305
gene id: 1185653:BBH88_RS07305
uniprot id: A0A1C7DIX2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family. RnhC subfamily.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1185653:BBH88 RS16245
gene id: 1185653:BBH88_RS16245
uniprot id: A0A1C7DEA6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS02630
gene id: 1185653:BBH88_RS02630
uniprot id: A0A1C7DCB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1185653:BBH88 RS00245
gene id: 1185653:BBH88_RS00245
uniprot id: A0A1C7DDJ6
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1185653:BBH88 RS07240
gene id: 1185653:BBH88_RS07240
uniprot id: A0A1C7DJ03
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1185653:BBH88 RS08530
gene id: 1185653:BBH88_RS08530
uniprot id: A0A1C7DIB3
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1185653:BBH88 RS16150
gene id: 1185653:BBH88_RS16150
uniprot id: A0A1C7DE04
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1185653:BBH88 RS02720
gene id: 1185653:BBH88_RS02720
uniprot id: A0A1C7DBM8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS08480
gene id: 1185653:BBH88_RS08480
uniprot id: A0A1C7DIC3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1185653:BBH88 RS13910
gene id: 1185653:BBH88_RS13910
uniprot id: A0A1C7DLS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FemABX family.
messages: Cytoplasm

1185653:BBH88 RS07925
gene id: 1185653:BBH88_RS07925
uniprot id: A0A1C7DIN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1185653:BBH88 RS09255
gene id: 1185653:BBH88_RS09255
uniprot id: A0A1C7DHS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS06755
gene id: 1185653:BBH88_RS06755
uniprot id: A0A1C7DIS6
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1185653:BBH88 RS14945
gene id: 1185653:BBH88_RS14945
uniprot id: A0A1C7DEK9
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. YrrT family.
messages: Could be a S-adenosyl-L-methionine-dependent methyltransferase.

1185653:BBH88 RS07465
gene id: 1185653:BBH88_RS07465
uniprot id: A0A1C7DID5
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

1185653:BBH88 RS09230
gene id: 1185653:BBH88_RS09230
uniprot id: A0A1C7DHI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1185653:BBH88 RS11855
gene id: 1185653:BBH88_RS11855
uniprot id: A0A1C7DG67
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1185653:BBH88 RS05870
gene id: 1185653:BBH88_RS05870
uniprot id: A0A1C7DJN5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1185653:BBH88 RS11455
gene id: 1185653:BBH88_RS11455
uniprot id: A0A1C7DKU8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1185653:BBH88 RS02135
gene id: 1185653:BBH88_RS02135
uniprot id: A0A1C7DCL0
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS17140
gene id: 1185653:BBH88_RS17140
uniprot id: A0A1C7DDR5
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1185653:BBH88 RS13705
gene id: 1185653:BBH88_RS13705
uniprot id: A0A1C7DFL4
names: Activity Regulation
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), including enzyme I, and histidine-containing protein (HPr) are required for the phosphorylation, which leads to the activation of the enzyme.

1185653:BBH88 RS18230
gene id: 1185653:BBH88_RS18230
uniprot id: A0A1C7DD76
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1185653:BBH88 RS16340
gene id: 1185653:BBH88_RS16340
uniprot id: A0A1C7DE64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1185653:BBH88 RS16190
gene id: 1185653:BBH88_RS16190
uniprot id: A0A1C7DEB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
messages: Membrane

1185653:BBH88 RS13645
gene id: 1185653:BBH88_RS13645
uniprot id: A0A1C7DF93
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS12170
gene id: 1185653:BBH88_RS12170
uniprot id: A0A1C7DG14
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

1185653:BBH88 RS04080
gene id: 1185653:BBH88_RS04080
uniprot id: A0A1C7DKI1
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

1185653:BBH88 RS18285
gene id: 1185653:BBH88_RS18285
uniprot id: A0A1C7DD62
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1185653:BBH88 RS12230
gene id: 1185653:BBH88_RS12230
uniprot id: A0A1C7DGU4
names: Similarity
messages: Belongs to the YggT family.

1185653:BBH88 RS15680
gene id: 1185653:BBH88_RS15680
uniprot id: A0A1C7DEE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1185653:BBH88 RS17375
gene id: 1185653:BBH88_RS17375
uniprot id: A0A1C7DDI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1185653:BBH88 RS09510
gene id: 1185653:BBH88_RS09510
uniprot id: A0A1C7DIC9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class U subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

1185653:BBH88 RS11990
gene id: 1185653:BBH88_RS11990
uniprot id: A0A1C7DGD5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1185653:BBH88 RS11960
gene id: 1185653:BBH88_RS11960
uniprot id: A0A1C7DG58
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1185653:BBH88 RS00650
gene id: 1185653:BBH88_RS00650
uniprot id: A0A1C7DCU4
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1185653:BBH88 RS01145
gene id: 1185653:BBH88_RS01145
uniprot id: A0A1C7DCE8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1185653:BBH88 RS07830
gene id: 1185653:BBH88_RS07830
uniprot id: A0A1C7DIM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

1185653:BBH88 RS11245
gene id: 1185653:BBH88_RS11245
uniprot id: A0A1C7DHI6
names: Similarity
names: Subunit
messages: Belongs to the MtrB family.
messages: Oligomer of 11 identical subunits arranged in doughnut-like structure.

1185653:BBH88 RS00995
gene id: 1185653:BBH88_RS00995
uniprot id: A0A1C7DCN1
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1185653:BBH88 RS14805
gene id: 1185653:BBH88_RS14805
uniprot id: A0A1C7DEU5
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

1185653:BBH88 RS07365
gene id: 1185653:BBH88_RS07365
uniprot id: A0A1C7DIR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1185653:BBH88 RS12160
gene id: 1185653:BBH88_RS12160
uniprot id: A0A1C7DGG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1185653:BBH88 RS06705
gene id: 1185653:BBH88_RS06705
uniprot id: A0A1C7DIQ7
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

1185653:BBH88 RS04740
gene id: 1185653:BBH88_RS04740
uniprot id: A0A1C7DJK1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1185653:BBH88 RS00065
gene id: 1185653:BBH88_RS00065
uniprot id: A0A1C7DD80
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1185653:BBH88 RS02130
gene id: 1185653:BBH88_RS02130
uniprot id: A0A1C7DC25
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

1185653:BBH88 RS04665
gene id: 1185653:BBH88_RS04665
uniprot id: A0A1C7DK80
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1185653:BBH88 RS16000
gene id: 1185653:BBH88_RS16000
uniprot id: A0A1C7DLA7
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1185653:BBH88 RS07065
gene id: 1185653:BBH88_RS07065
uniprot id: A0A1C7DJF5
names: Similarity
messages: Belongs to the UPF0173 family.

1185653:BBH88 RS02155
gene id: 1185653:BBH88_RS02155
uniprot id: A0A1C7DBW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS02455
gene id: 1185653:BBH88_RS02455
uniprot id: A0A1C7DC32
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS09355
gene id: 1185653:BBH88_RS09355
uniprot id: A0A1C7DHF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS12195
gene id: 1185653:BBH88_RS12195
uniprot id: A0A1C7DGF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1185653:BBH88 RS12855
gene id: 1185653:BBH88_RS12855
uniprot id: A0A1C7DGM8
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. YjcG family.

1185653:BBH88 RS01395
gene id: 1185653:BBH88_RS01395
uniprot id: A0A1C7DCL3
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS01980
gene id: 1185653:BBH88_RS01980
uniprot id: A0A1C7DCC2
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1185653:BBH88 RS16060
gene id: 1185653:BBH88_RS16060
uniprot id: A0A1C7DEA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS07160
gene id: 1185653:BBH88_RS07160
uniprot id: A0A1C7DJJ7
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1185653:BBH88 RS11400
gene id: 1185653:BBH88_RS11400
uniprot id: A0A1C7DHF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

1185653:BBH88 RS11155
gene id: 1185653:BBH88_RS11155
uniprot id: A0A1C7DGI9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS03580
gene id: 1185653:BBH88_RS03580
uniprot id: A0A1C7DL94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS08340
gene id: 1185653:BBH88_RS08340
uniprot id: A0A1C7DIE0
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1185653:BBH88 RS13860
gene id: 1185653:BBH88_RS13860
uniprot id: A0A1C7DFH5
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS07585
gene id: 1185653:BBH88_RS07585
uniprot id: A0A1C7DIT7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1185653:BBH88 RS16800
gene id: 1185653:BBH88_RS16800
uniprot id: A0A1C7DDN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS12660
gene id: 1185653:BBH88_RS12660
uniprot id: A0A1C7DFS2
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family. DapH subfamily.
messages: Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.

1185653:BBH88 RS12035
gene id: 1185653:BBH88_RS12035
uniprot id: A0A1C7DG90
names: Similarity
messages: Belongs to the asp23 family.

1185653:BBH88 RS11755
gene id: 1185653:BBH88_RS11755
uniprot id: A0A1C7DGN2
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

1185653:BBH88 RS00350
gene id: 1185653:BBH88_RS00350
uniprot id: A0A1C7DCY6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1185653:BBH88 RS17355
gene id: 1185653:BBH88_RS17355
uniprot id: A0A1C7DDF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1185653:BBH88 RS08430
gene id: 1185653:BBH88_RS08430
uniprot id: A0A1C7DI26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1185653:BBH88 RS14215
gene id: 1185653:BBH88_RS14215
uniprot id: A0A1C7DFC8
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1185653:BBH88 RS18080
gene id: 1185653:BBH88_RS18080
uniprot id: A0A1C7DDV4
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

1185653:BBH88 RS04785
gene id: 1185653:BBH88_RS04785
uniprot id: A0A1C7DJL3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1185653:BBH88 RS10645
gene id: 1185653:BBH88_RS10645
uniprot id: A0A1C7DH82
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1185653:BBH88 RS04825
gene id: 1185653:BBH88_RS04825
uniprot id: A0A1C7DK48
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1185653:BBH88 RS00805
gene id: 1185653:BBH88_RS00805
uniprot id: A0A1C7DCR4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1185653:BBH88 RS09765
gene id: 1185653:BBH88_RS09765
uniprot id: A0A1C7DHE4
names: Cofactor
messages: Can also use Mn(2+) ion.

1185653:BBH88 RS08105
gene id: 1185653:BBH88_RS08105
uniprot id: A0A1C7DIG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS07955
gene id: 1185653:BBH88_RS07955
uniprot id: A0A1C7DIK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1185653:BBH88 RS15130
gene id: 1185653:BBH88_RS15130
uniprot id: A0A1C7DEN8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1185653:BBH88 RS09700
gene id: 1185653:BBH88_RS09700
uniprot id: A0A1C7DH99
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS04900
gene id: 1185653:BBH88_RS04900
uniprot id: A0A1C7DKK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1185653:BBH88 RS07675
gene id: 1185653:BBH88_RS07675
uniprot id: A0A1C7DKZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1185653:BBH88 RS04380
gene id: 1185653:BBH88_RS04380
uniprot id: A0A1C7DKV1
names: Similarity
messages: Belongs to the AHA1 family.

1185653:BBH88 RS02575
gene id: 1185653:BBH88_RS02575
uniprot id: A0A1C7DC10
names: Similarity
messages: Belongs to the TrpC family.

1185653:BBH88 RS12280
gene id: 1185653:BBH88_RS12280
uniprot id: A0A1C7DGT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS02570
gene id: 1185653:BBH88_RS02570
uniprot id: A0A1C7DCC5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1185653:BBH88 RS08300
gene id: 1185653:BBH88_RS08300
uniprot id: A0A1C7DHZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1185653:BBH88 RS00865
gene id: 1185653:BBH88_RS00865
uniprot id: A0A1C7DCU8
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1185653:BBH88 RS04980
gene id: 1185653:BBH88_RS04980
uniprot id: A0A1C7DK20
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1185653:BBH88 RS02160
gene id: 1185653:BBH88_RS02160
uniprot id: A0A1C7DC16
names: Subcellular Location Annotation
messages: Cell membrane

1185653:BBH88 RS12125
gene id: 1185653:BBH88_RS12125
uniprot id: A0A1C7DG17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS03365
gene id: 1185653:BBH88_RS03365
uniprot id: A0A1C7DKW5
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS08490
gene id: 1185653:BBH88_RS08490
uniprot id: A0A1C7DI15
names: Similarity
messages: Belongs to the TlyA family.

1185653:BBH88 RS05150
gene id: 1185653:BBH88_RS05150
uniprot id: A0A1C7DJV6
names: Similarity
messages: Belongs to the UPF0435 family.

1185653:BBH88 RS09195
gene id: 1185653:BBH88_RS09195
uniprot id: A0A1C7DHP3
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS03305
gene id: 1185653:BBH88_RS03305
uniprot id: A0A1C7DLE4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

1185653:BBH88 RS00375
gene id: 1185653:BBH88_RS00375
uniprot id: A0A1C7DDB8
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1185653:BBH88 RS11980
gene id: 1185653:BBH88_RS11980
uniprot id: A0A1C7DGJ1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1185653:BBH88 RS13310
gene id: 1185653:BBH88_RS13310
uniprot id: A0A1C7DFF6
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1185653:BBH88 RS13395
gene id: 1185653:BBH88_RS13395
uniprot id: A0A1C7DFN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS13115
gene id: 1185653:BBH88_RS13115
uniprot id: A0A1C7DGG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

1185653:BBH88 RS00695
gene id: 1185653:BBH88_RS00695
uniprot id: A0A1C7DCP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1185653:BBH88 RS13775
gene id: 1185653:BBH88_RS13775
uniprot id: A0A1C7DFG3
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS07680
gene id: 1185653:BBH88_RS07680
uniprot id: A0A1C7DIA5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1185653:BBH88 RS12205
gene id: 1185653:BBH88_RS12205
uniprot id: A0A1C7DKU2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1185653:BBH88 RS01090
gene id: 1185653:BBH88_RS01090
uniprot id: A0A1C7DCG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1185653:BBH88 RS06290
gene id: 1185653:BBH88_RS06290
uniprot id: A0A1C7DIY3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1185653:BBH88 RS03290
gene id: 1185653:BBH88_RS03290
uniprot id: A0A1C7DKK8
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1185653:BBH88 RS12420
gene id: 1185653:BBH88_RS12420
uniprot id: A0A1C7DG71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Membrane

1185653:BBH88 RS00710
gene id: 1185653:BBH88_RS00710
uniprot id: A0A1C7DDB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1185653:BBH88 RS12455
gene id: 1185653:BBH88_RS12455
uniprot id: A0A1C7DG96
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS05800
gene id: 1185653:BBH88_RS05800
uniprot id: A0A1C7DK13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1185653:BBH88 RS08000
gene id: 1185653:BBH88_RS08000
uniprot id: A0A1C7DII5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1185653:BBH88 RS02315
gene id: 1185653:BBH88_RS02315
uniprot id: A0A1C7DBU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Cytoplasm

1185653:BBH88 RS07750
gene id: 1185653:BBH88_RS07750
uniprot id: A0A1C7DLJ9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1185653:BBH88 RS08410
gene id: 1185653:BBH88_RS08410
uniprot id: A0A1C7DHV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1185653:BBH88 RS08745
gene id: 1185653:BBH88_RS08745
uniprot id: A0A1C7DHP8
names: Similarity
messages: Belongs to the HesB/IscA family.

1185653:BBH88 RS08600
gene id: 1185653:BBH88_RS08600
uniprot id: A0A1C7DHZ2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1185653:BBH88 RS03175
gene id: 1185653:BBH88_RS03175
uniprot id: A0A1C7DKW9
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS06095
gene id: 1185653:BBH88_RS06095
uniprot id: A0A1C7DJJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1185653:BBH88 RS12485
gene id: 1185653:BBH88_RS12485
uniprot id: A0A1C7DGA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1185653:BBH88 RS12545
gene id: 1185653:BBH88_RS12545
uniprot id: A0A1C7DGN6
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1185653:BBH88 RS17905
gene id: 1185653:BBH88_RS17905
uniprot id: A0A1C7DD90
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1185653:BBH88 RS07010
gene id: 1185653:BBH88_RS07010
uniprot id: A0A1C7DJM3
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS05585
gene id: 1185653:BBH88_RS05585
uniprot id: A0A1C7DK53
names: Similarity
messages: Belongs to the universal stress protein A family.

1185653:BBH88 RS12445
gene id: 1185653:BBH88_RS12445
uniprot id: A0A1C7DL90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COX15/CtaA family. Type 1 subfamily.
messages: Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8. The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
messages: Cell membrane
messages: Interacts with CtaB.
messages: Membrane

1185653:BBH88 RS13065
gene id: 1185653:BBH88_RS13065
uniprot id: A0A1C7DGI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

1185653:BBH88 RS01165
gene id: 1185653:BBH88_RS01165
uniprot id: A0A1C7DCG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

1185653:BBH88 RS02035
gene id: 1185653:BBH88_RS02035
uniprot id: A0A1C7DCM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1185653:BBH88 RS04925
gene id: 1185653:BBH88_RS04925
uniprot id: A0A1C7DK33
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1185653:BBH88 RS06490
gene id: 1185653:BBH88_RS06490
uniprot id: A0A1C7DJA1
names: Similarity
messages: Belongs to the isochorismate synthase family.

1185653:BBH88 RS12430
gene id: 1185653:BBH88_RS12430
uniprot id: A0A1C7DGB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1185653:BBH88 RS01855
gene id: 1185653:BBH88_RS01855
uniprot id: A0A1C7DCE2
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1185653:BBH88 RS08735
gene id: 1185653:BBH88_RS08735
uniprot id: A0A1C7DIJ2
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1185653:BBH88 RS09465
gene id: 1185653:BBH88_RS09465
uniprot id: A0A1C7DHE9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1185653:BBH88 RS08915
gene id: 1185653:BBH88_RS08915
uniprot id: A0A1C7DIG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS05965
gene id: 1185653:BBH88_RS05965
uniprot id: A0A1C7DJX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1185653:BBH88 RS07695
gene id: 1185653:BBH88_RS07695
uniprot id: A0A1C7DIR8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1185653:BBH88 RS11840
gene id: 1185653:BBH88_RS11840
uniprot id: A0A1C7DGL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1185653:BBH88 RS04520
gene id: 1185653:BBH88_RS04520
uniprot id: A0A1C7DJR2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS04550
gene id: 1185653:BBH88_RS04550
uniprot id: A0A1C7DK72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS03030
gene id: 1185653:BBH88_RS03030
uniprot id: A0A1C7DL06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

1185653:BBH88 RS01845
gene id: 1185653:BBH88_RS01845
uniprot id: A0A1C7DC77
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

1185653:BBH88 RS16055
gene id: 1185653:BBH88_RS16055
uniprot id: A0A1C7DE35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS06320
gene id: 1185653:BBH88_RS06320
uniprot id: A0A1C7DJB1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family. RocA subfamily.

1185653:BBH88 RS01305
gene id: 1185653:BBH88_RS01305
uniprot id: A0A1C7DCB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS11945
gene id: 1185653:BBH88_RS11945
uniprot id: A0A1C7DLU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1185653:BBH88 RS08265
gene id: 1185653:BBH88_RS08265
uniprot id: A0A1C7DIE6
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

1185653:BBH88 RS10865
gene id: 1185653:BBH88_RS10865
uniprot id: A0A1C7DGQ3
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1185653:BBH88 RS01390
gene id: 1185653:BBH88_RS01390
uniprot id: A0A1C7DCY1
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS15000
gene id: 1185653:BBH88_RS15000
uniprot id: A0A1C7DEK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1185653:BBH88 RS07165
gene id: 1185653:BBH88_RS07165
uniprot id: A0A1C7DJ11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1185653:BBH88 RS02905
gene id: 1185653:BBH88_RS02905
uniprot id: A0A1C7DC70
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1185653:BBH88 RS07210
gene id: 1185653:BBH88_RS07210
uniprot id: A0A1C7DIX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1185653:BBH88 RS15175
gene id: 1185653:BBH88_RS15175
uniprot id: A0A1C7DEU6
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS16400
gene id: 1185653:BBH88_RS16400
uniprot id: A0A1C7DE34
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1185653:BBH88 RS14530
gene id: 1185653:BBH88_RS14530
uniprot id: A0A1C7DEZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1185653:BBH88 RS14235
gene id: 1185653:BBH88_RS14235
uniprot id: A0A1C7DFW4
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS03865
gene id: 1185653:BBH88_RS03865
uniprot id: A0A1C7DKM7
names: Similarity
messages: Belongs to the glutamate synthase family.

1185653:BBH88 RS00970
gene id: 1185653:BBH88_RS00970
uniprot id: A0A1C7DD73
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

1185653:BBH88 RS07610
gene id: 1185653:BBH88_RS07610
uniprot id: A0A1C7DJA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

1185653:BBH88 RS07355
gene id: 1185653:BBH88_RS07355
uniprot id: A0A1C7DIW2
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1185653:BBH88 RS03530
gene id: 1185653:BBH88_RS03530
uniprot id: A0A1C7DKT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1185653:BBH88 RS00670
gene id: 1185653:BBH88_RS00670
uniprot id: A0A1C7DD75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1185653:BBH88 RS17070
gene id: 1185653:BBH88_RS17070
uniprot id: A0A1C7DDM6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. ABCF family. ARE2 subfamily.
messages: Binds within the E-site of the 70S ribosome, where it contacts ribosomal proteins of the large and small subunit, the 16 and 23S rRNAs and the acceptor arm of the P-site tRNA.
messages: Cytoplasm
messages: Recognizes and binds in the vacant E-site of ribosomes stalled by some peptidyltransferase center (PTC)-targeting antibiotics. Makes contact with the PTC and both ribosomal subunits. Induces conformational changes in the P-site, which allows it to dislodge the antibiotic from its PTC binding site.
messages: The antibiotic resistance domain (ARD) is packed between the 23S rRNA and the acceptor arm of the P-site tRNA and inserts into the peptidyltransferase center (PTC). The C-terminal extension (CTE) contacts the small ribosomal subunit, positioned in the Shine-Dalgarno-anti-Shine-Dalgarno cavity.

1185653:BBH88 RS13140
gene id: 1185653:BBH88_RS13140
uniprot id: A0A1C7DFI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1185653:BBH88 RS01310
gene id: 1185653:BBH88_RS01310
uniprot id: A0A1C7DCC0
names: Subcellular Location Annotation
messages: Cell membrane

1185653:BBH88 RS08295
gene id: 1185653:BBH88_RS08295
uniprot id: A0A1C7DIR9
names: Similarity
messages: Belongs to the transpeptidase family.

1185653:BBH88 RS13585
gene id: 1185653:BBH88_RS13585
uniprot id: A0A1C7DFM5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1185653:BBH88 RS11985
gene id: 1185653:BBH88_RS11985
uniprot id: A0A1C7DG99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1185653:BBH88 RS09605
gene id: 1185653:BBH88_RS09605
uniprot id: A0A1C7DHR9
names: Function
names: Similarity
messages: Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.

1185653:BBH88 RS17985
gene id: 1185653:BBH88_RS17985
uniprot id: A0A1C7DDS3
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1185653:BBH88 RS00645
gene id: 1185653:BBH88_RS00645
uniprot id: A0A1C7DCQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1185653:BBH88 RS16345
gene id: 1185653:BBH88_RS16345
uniprot id: A0A1C7DE49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EmrB family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS14730
gene id: 1185653:BBH88_RS14730
uniprot id: A0A1C7DEQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1185653:BBH88 RS15355
gene id: 1185653:BBH88_RS15355
uniprot id: A0A1C7DEN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1185653:BBH88 RS14895
gene id: 1185653:BBH88_RS14895
uniprot id: A0A1C7DEM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS08590
gene id: 1185653:BBH88_RS08590
uniprot id: A0A1C7DIA3
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1185653:BBH88 RS14665
gene id: 1185653:BBH88_RS14665
uniprot id: A0A1C7DF48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RpoE family.
messages: Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunits. The core is associated with a delta subunit and one of several sigma factors.

1185653:BBH88 RS00120
gene id: 1185653:BBH88_RS00120
uniprot id: A0A1C7DDM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1185653:BBH88 RS00555
gene id: 1185653:BBH88_RS00555
uniprot id: A0A1C7DCW1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1185653:BBH88 RS12460
gene id: 1185653:BBH88_RS12460
uniprot id: A0A1C7DGA2
names: Similarity
messages: Belongs to the UPF0358 family.

1185653:BBH88 RS12405
gene id: 1185653:BBH88_RS12405
uniprot id: A0A1C7DGB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1185653:BBH88 RS08045
gene id: 1185653:BBH88_RS08045
uniprot id: A0A1C7DID3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1185653:BBH88 RS13930
gene id: 1185653:BBH88_RS13930
uniprot id: A0A1C7DFA0
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1185653:BBH88 RS06555
gene id: 1185653:BBH88_RS06555
uniprot id: A0A1C7DJV2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1185653:BBH88 RS08470
gene id: 1185653:BBH88_RS08470
uniprot id: A0A1C7DHW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1185653:BBH88 RS00890
gene id: 1185653:BBH88_RS00890
uniprot id: A0A1C7DCI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1185653:BBH88 RS11870
gene id: 1185653:BBH88_RS11870
uniprot id: A0A1C7DGB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1185653:BBH88 RS18005
gene id: 1185653:BBH88_RS18005
uniprot id: A0A1C7DDE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

1185653:BBH88 RS14820
gene id: 1185653:BBH88_RS14820
uniprot id: A0A1C7DFK5
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the octanoyltransferase LipL family.
messages: Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes.
messages: The reaction proceeds via a thioester-linked acyl-enzyme intermediate.

1185653:BBH88 RS10845
gene id: 1185653:BBH88_RS10845
uniprot id: A0A1C7DHQ7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS02320
gene id: 1185653:BBH88_RS02320
uniprot id: A0A1C7DBY1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1185653:BBH88 RS07155
gene id: 1185653:BBH88_RS07155
uniprot id: A0A1C7DIY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1185653:BBH88 RS02530
gene id: 1185653:BBH88_RS02530
uniprot id: A0A1C7DBQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell membrane
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

1185653:BBH88 RS13005
gene id: 1185653:BBH88_RS13005
uniprot id: A0A1C7DFW2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1185653:BBH88 RS12415
gene id: 1185653:BBH88_RS12415
uniprot id: A0A1C7DG52
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS12880
gene id: 1185653:BBH88_RS12880
uniprot id: A0A1C7DLB0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1185653:BBH88 RS11570
gene id: 1185653:BBH88_RS11570
uniprot id: A0A1C7DGR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

1185653:BBH88 RS08005
gene id: 1185653:BBH88_RS08005
uniprot id: A0A1C7DJ36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

1185653:BBH88 RS15375
gene id: 1185653:BBH88_RS15375
uniprot id: A0A1C7DER2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1185653:BBH88 RS15125
gene id: 1185653:BBH88_RS15125
uniprot id: A0A1C7DEV6
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1185653:BBH88 RS00685
gene id: 1185653:BBH88_RS00685
uniprot id: A0A1C7DCT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1185653:BBH88 RS11830
gene id: 1185653:BBH88_RS11830
uniprot id: A0A1C7DGH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1185653:BBH88 RS13070
gene id: 1185653:BBH88_RS13070
uniprot id: A0A1C7DFY8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddB/RexB type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of AddA and AddB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.

1185653:BBH88 RS07325
gene id: 1185653:BBH88_RS07325
uniprot id: A0A1C7DJG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

1185653:BBH88 RS08605
gene id: 1185653:BBH88_RS08605
uniprot id: A0A1C7DI30
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1185653:BBH88 RS03240
gene id: 1185653:BBH88_RS03240
uniprot id: A0A1C7DKL8
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
messages: In the C-terminal section; belongs to the MsrB Met sulfoxide reductase family.
messages: In the N-terminal section; belongs to the MsrA Met sulfoxide reductase family.

1185653:BBH88 RS10340
gene id: 1185653:BBH88_RS10340
uniprot id: A0A1C7DH45
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS14525
gene id: 1185653:BBH88_RS14525
uniprot id: A0A1C7DF69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1185653:BBH88 RS08235
gene id: 1185653:BBH88_RS08235
uniprot id: A0A1C7DIZ1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1185653:BBH88 RS10330
gene id: 1185653:BBH88_RS10330
uniprot id: A0A1C7DHE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1185653:BBH88 RS02750
gene id: 1185653:BBH88_RS02750
uniprot id: A0A1C7DC54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS17135
gene id: 1185653:BBH88_RS17135
uniprot id: A0A1C7DDL7
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1185653:BBH88 RS15665
gene id: 1185653:BBH88_RS15665
uniprot id: A0A1C7DE86
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

1185653:BBH88 RS00760
gene id: 1185653:BBH88_RS00760
uniprot id: A0A1C7DDA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1185653:BBH88 RS09220
gene id: 1185653:BBH88_RS09220
uniprot id: A0A1C7DHZ7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1185653:BBH88 RS11395
gene id: 1185653:BBH88_RS11395
uniprot id: A0A1C7DGR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpB family.
messages: Cytoplasm
messages: Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

1185653:BBH88 RS07130
gene id: 1185653:BBH88_RS07130
uniprot id: A0A1C7DII3
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1185653:BBH88 RS18240
gene id: 1185653:BBH88_RS18240
uniprot id: A0A1C7DDS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1185653:BBH88 RS09610
gene id: 1185653:BBH88_RS09610
uniprot id: A0A1C7DHH6
names: Similarity
messages: Belongs to the peptidase S51 family.

1185653:BBH88 RS04160
gene id: 1185653:BBH88_RS04160
uniprot id: A0A1C7DKD9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1185653:BBH88 RS11640
gene id: 1185653:BBH88_RS11640
uniprot id: A0A1C7DGA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1185653:BBH88 RS11425
gene id: 1185653:BBH88_RS11425
uniprot id: A0A1C7DGU2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

1185653:BBH88 RS12250
gene id: 1185653:BBH88_RS12250
uniprot id: A0A1C7DGE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1185653:BBH88 RS00535
gene id: 1185653:BBH88_RS00535
uniprot id: A0A1C7DCW4
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1185653:BBH88 RS06740
gene id: 1185653:BBH88_RS06740
uniprot id: A0A1C7DJS5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS06515
gene id: 1185653:BBH88_RS06515
uniprot id: A0A1C7DIT1
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

1185653:BBH88 RS03100
gene id: 1185653:BBH88_RS03100
uniprot id: A0A1C7DL11
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1185653:BBH88 RS06325
gene id: 1185653:BBH88_RS06325
uniprot id: A0A1C7DJX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily.
messages: Catalyzes the interconversion of ornithine to glutamate semialdehyde.
messages: Cytoplasm

1185653:BBH88 RS04395
gene id: 1185653:BBH88_RS04395
uniprot id: A0A1C7DKP1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS11875
gene id: 1185653:BBH88_RS11875
uniprot id: A0A1C7DGE9
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1185653:BBH88 RS07190
gene id: 1185653:BBH88_RS07190
uniprot id: A0A1C7DJ18
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1185653:BBH88 RS10555
gene id: 1185653:BBH88_RS10555
uniprot id: A0A1C7DH01
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Forms a 24-polypeptide structural core with octahedral symmetry. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

1185653:BBH88 RS05935
gene id: 1185653:BBH88_RS05935
uniprot id: A0A1C7DJA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1185653:BBH88 RS10490
gene id: 1185653:BBH88_RS10490
uniprot id: A0A1C7DGV7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS05825
gene id: 1185653:BBH88_RS05825
uniprot id: A0A1C7DJK8
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

1185653:BBH88 RS13120
gene id: 1185653:BBH88_RS13120
uniprot id: A0A1C7DFX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1185653:BBH88 RS00260
gene id: 1185653:BBH88_RS00260
uniprot id: A0A1C7DCU2
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

1185653:BBH88 RS01140
gene id: 1185653:BBH88_RS01140
uniprot id: A0A1C7DCZ8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1185653:BBH88 RS07735
gene id: 1185653:BBH88_RS07735
uniprot id: A0A1C7DI95
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1185653:BBH88 RS11560
gene id: 1185653:BBH88_RS11560
uniprot id: A0A1C7DGN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0154 family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS16315
gene id: 1185653:BBH88_RS16315
uniprot id: A0A1C7DDY6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS01880
gene id: 1185653:BBH88_RS01880
uniprot id: A0A1C7DC65
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1185653:BBH88 RS12085
gene id: 1185653:BBH88_RS12085
uniprot id: A0A1C7DG78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1185653:BBH88 RS00800
gene id: 1185653:BBH88_RS00800
uniprot id: A0A1C7DCR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1185653:BBH88 RS17510
gene id: 1185653:BBH88_RS17510
uniprot id: A0A1C7DDP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1185653:BBH88 RS15970
gene id: 1185653:BBH88_RS15970
uniprot id: A0A1C7DEB1
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1185653:BBH88 RS15230
gene id: 1185653:BBH88_RS15230
uniprot id: A0A1C7DEG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1185653:BBH88 RS05650
gene id: 1185653:BBH88_RS05650
uniprot id: A0A1C7DJ93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PrsA family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.

1185653:BBH88 RS18400
gene id: 1185653:BBH88_RS18400
uniprot id: A0A1C7DD91
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1185653:BBH88 RS11305
gene id: 1185653:BBH88_RS11305
uniprot id: A0A1C7DGX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease PrsW family.
messages: Cell membrane
messages: Involved in the degradation of specific anti-sigma factors.
messages: Membrane

1185653:BBH88 RS17130
gene id: 1185653:BBH88_RS17130
uniprot id: A0A1C7DDT7
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

1185653:BBH88 RS02560
gene id: 1185653:BBH88_RS02560
uniprot id: A0A1C7DBU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS15360
gene id: 1185653:BBH88_RS15360
uniprot id: A0A1C7DL63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1185653:BBH88 RS14535
gene id: 1185653:BBH88_RS14535
uniprot id: A0A1C7DF30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1185653:BBH88 RS11275
gene id: 1185653:BBH88_RS11275
uniprot id: A0A1C7DGX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1185653:BBH88 RS15090
gene id: 1185653:BBH88_RS15090
uniprot id: A0A1C7DFF3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1185653:BBH88 RS02200
gene id: 1185653:BBH88_RS02200
uniprot id: A0A1C7DBW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

1185653:BBH88 RS13050
gene id: 1185653:BBH88_RS13050
uniprot id: A0A1C7DFR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0344 family.
messages: Cell membrane

1185653:BBH88 RS17980
gene id: 1185653:BBH88_RS17980
uniprot id: A0A1C7DDG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS17975
gene id: 1185653:BBH88_RS17975
uniprot id: A0A1C7DDX2
names: Similarity
messages: Belongs to the alkaline phosphatase family.

1185653:BBH88 RS02790
gene id: 1185653:BBH88_RS02790
uniprot id: A0A1C7DC88
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS06560
gene id: 1185653:BBH88_RS06560
uniprot id: A0A1C7DJC4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1185653:BBH88 RS08055
gene id: 1185653:BBH88_RS08055
uniprot id: A0A1C7DJ26
names: PTM
messages: Binds 1 heme c group covalently per subunit.

1185653:BBH88 RS05955
gene id: 1185653:BBH88_RS05955
uniprot id: A0A1C7DK40
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1185653:BBH88 RS15435
gene id: 1185653:BBH88_RS15435
uniprot id: A0A1C7DEC2
names: Similarity
messages: Belongs to the PemK/MazF family.

1185653:BBH88 RS07890
gene id: 1185653:BBH88_RS07890
uniprot id: A0A1C7DIG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1185653:BBH88 RS17345
gene id: 1185653:BBH88_RS17345
uniprot id: A0A1C7DE47
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1185653:BBH88 RS01160
gene id: 1185653:BBH88_RS01160
uniprot id: A0A1C7DCM9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1185653:BBH88 RS08245
gene id: 1185653:BBH88_RS08245
uniprot id: A0A1C7DIT0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1185653:BBH88 RS08110
gene id: 1185653:BBH88_RS08110
uniprot id: A0A1C7DJ16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS12800
gene id: 1185653:BBH88_RS12800
uniprot id: A0A1C7DG44
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1185653:BBH88 RS00655
gene id: 1185653:BBH88_RS00655
uniprot id: A0A1C7DCU1
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1185653:BBH88 RS05925
gene id: 1185653:BBH88_RS05925
uniprot id: A0A1C7DJM6
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

1185653:BBH88 RS14415
gene id: 1185653:BBH88_RS14415
uniprot id: A0A1C7DF70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1185653:BBH88 RS01990
gene id: 1185653:BBH88_RS01990
uniprot id: A0A1C7DC06
names: Similarity
messages: Belongs to the UPF0398 family.

1185653:BBH88 RS05560
gene id: 1185653:BBH88_RS05560
uniprot id: A0A1C7DJM4
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS07730
gene id: 1185653:BBH88_RS07730
uniprot id: A0A1C7DJ27
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1185653:BBH88 RS04760
gene id: 1185653:BBH88_RS04760
uniprot id: A0A1C7DJZ4
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS16330
gene id: 1185653:BBH88_RS16330
uniprot id: A0A1C7DE18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

1185653:BBH88 RS07360
gene id: 1185653:BBH88_RS07360
uniprot id: A0A1C7DIM4
names: Similarity
messages: Belongs to the thioredoxin family.

1185653:BBH88 RS12210
gene id: 1185653:BBH88_RS12210
uniprot id: A0A1C7DG93
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1185653:BBH88 RS10155
gene id: 1185653:BBH88_RS10155
uniprot id: A0A1C7DH22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1185653:BBH88 RS08710
gene id: 1185653:BBH88_RS08710
uniprot id: A0A1C7DHX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1185653:BBH88 RS15525
gene id: 1185653:BBH88_RS15525
uniprot id: A0A1C7DEJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1185653:BBH88 RS14140
gene id: 1185653:BBH88_RS14140
uniprot id: A0A1C7DF09
names: Similarity
messages: Belongs to the peptidase S8 family.

1185653:BBH88 RS00130
gene id: 1185653:BBH88_RS00130
uniprot id: A0A1C7DDH1
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1185653:BBH88 RS00095
gene id: 1185653:BBH88_RS00095
uniprot id: A0A1C7DCY8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS04475
gene id: 1185653:BBH88_RS04475
uniprot id: A0A1C7DLJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS08840
gene id: 1185653:BBH88_RS08840
uniprot id: A0A1C7DI33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1185653:BBH88 RS12190
gene id: 1185653:BBH88_RS12190
uniprot id: A0A1C7DGE5
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1185653:BBH88 RS17335
gene id: 1185653:BBH88_RS17335
uniprot id: A0A1C7DDR9
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1185653:BBH88 RS14680
gene id: 1185653:BBH88_RS14680
uniprot id: A0A1C7DER3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1185653:BBH88 RS15755
gene id: 1185653:BBH88_RS15755
uniprot id: A0A1C7DF39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS08240
gene id: 1185653:BBH88_RS08240
uniprot id: A0A1C7DIF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. CshB subfamily.
messages: Cytoplasm
messages: Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures.

1185653:BBH88 RS11885
gene id: 1185653:BBH88_RS11885
uniprot id: A0A1C7DH64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1185653:BBH88 RS06265
gene id: 1185653:BBH88_RS06265
uniprot id: A0A1C7DJ91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Membrane

1185653:BBH88 RS07550
gene id: 1185653:BBH88_RS07550
uniprot id: A0A1C7DIM3
names: Function
messages: Required for transformation and DNA binding.

1185653:BBH88 RS15035
gene id: 1185653:BBH88_RS15035
uniprot id: A0A1C7DET3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.

1185653:BBH88 RS12610
gene id: 1185653:BBH88_RS12610
uniprot id: A0A1C7DFT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS18290
gene id: 1185653:BBH88_RS18290
uniprot id: A0A1C7DDR3
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1185653:BBH88 RS00680
gene id: 1185653:BBH88_RS00680
uniprot id: A0A1C7DCM8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1185653:BBH88 RS08560
gene id: 1185653:BBH88_RS08560
uniprot id: A0A1C7DL43
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1185653:BBH88 RS15670
gene id: 1185653:BBH88_RS15670
uniprot id: A0A1C7DEH7
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

1185653:BBH88 RS06110
gene id: 1185653:BBH88_RS06110
uniprot id: A0A1C7DJC1
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1185653:BBH88 RS00640
gene id: 1185653:BBH88_RS00640
uniprot id: A0A1C7DCW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1185653:BBH88 RS01920
gene id: 1185653:BBH88_RS01920
uniprot id: A0A1C7DC15
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

1185653:BBH88 RS05890
gene id: 1185653:BBH88_RS05890
uniprot id: A0A1C7DJG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1185653:BBH88 RS06025
gene id: 1185653:BBH88_RS06025
uniprot id: A0A1C7DJ25
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS11540
gene id: 1185653:BBH88_RS11540
uniprot id: A0A1C7DGS3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1185653:BBH88 RS11895
gene id: 1185653:BBH88_RS11895
uniprot id: A0A1C7DLB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1185653:BBH88 RS09265
gene id: 1185653:BBH88_RS09265
uniprot id: A0A1C7DIG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS06100
gene id: 1185653:BBH88_RS06100
uniprot id: A0A1C7DJF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1185653:BBH88 RS13795
gene id: 1185653:BBH88_RS13795
uniprot id: A0A1C7DFZ7
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

1185653:BBH88 RS12910
gene id: 1185653:BBH88_RS12910
uniprot id: A0A1C7DGM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adapter protein required for efficient degradation of Spx by ClpXP under non-stress conditions. Interaction with Spx stabilizes Spx and exposes the C-terminus of Spx for recognition and proteolysis by ClpXP.
messages: Belongs to the SpxH family.
messages: Cytoplasm
messages: Interacts with Spx.

1185653:BBH88 RS15865
gene id: 1185653:BBH88_RS15865
uniprot id: A0A1C7DED1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS08505
gene id: 1185653:BBH88_RS08505
uniprot id: A0A1C7DIU4
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with Spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. Repressor of abrB, activator of the spoIIa operon. Binds the DNA sequence 5'-TGNCGAA-3' (0A box).
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

1185653:BBH88 RS05155
gene id: 1185653:BBH88_RS05155
uniprot id: A0A1C7DJM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS08440
gene id: 1185653:BBH88_RS08440
uniprot id: A0A1C7DI59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1185653:BBH88 RS09955
gene id: 1185653:BBH88_RS09955
uniprot id: A0A1C7DHF1
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

1185653:BBH88 RS00735
gene id: 1185653:BBH88_RS00735
uniprot id: A0A1C7DCS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1185653:BBH88 RS03165
gene id: 1185653:BBH88_RS03165
uniprot id: A0A1C7DKF4
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS09735
gene id: 1185653:BBH88_RS09735
uniprot id: A0A1C7DHP1
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1185653:BBH88 RS13130
gene id: 1185653:BBH88_RS13130
uniprot id: A0A1C7DFJ0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS04915
gene id: 1185653:BBH88_RS04915
uniprot id: A0A1C7DJJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1185653:BBH88 RS08050
gene id: 1185653:BBH88_RS08050
uniprot id: A0A1C7DIH3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1185653:BBH88 RS11500
gene id: 1185653:BBH88_RS11500
uniprot id: A0A1C7DGM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS17475
gene id: 1185653:BBH88_RS17475
uniprot id: A0A1C7DDD0
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1185653:BBH88 RS08455
gene id: 1185653:BBH88_RS08455
uniprot id: A0A1C7DIV4
names: Similarity
messages: Belongs to the asp23 family.

1185653:BBH88 RS00520
gene id: 1185653:BBH88_RS00520
uniprot id: A0A1C7DDA8
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1185653:BBH88 RS02490
gene id: 1185653:BBH88_RS02490
uniprot id: A0A1C7DBS0
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS08405
gene id: 1185653:BBH88_RS08405
uniprot id: A0A1C7DHX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1185653:BBH88 RS13125
gene id: 1185653:BBH88_RS13125
uniprot id: A0A1C7DGB6
names: PTM
messages: Binds 1 heme c group covalently per subunit.

1185653:BBH88 RS01215
gene id: 1185653:BBH88_RS01215
uniprot id: A0A1C7DCL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

1185653:BBH88 RS09920
gene id: 1185653:BBH88_RS09920
uniprot id: A0A1C7DHL0
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1185653:BBH88 RS13420
gene id: 1185653:BBH88_RS13420
uniprot id: A0A1C7DFD6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1185653:BBH88 RS18310
gene id: 1185653:BBH88_RS18310
uniprot id: A0A1C7DD59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1185653:BBH88 RS04800
gene id: 1185653:BBH88_RS04800
uniprot id: A0A1C7DK17
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS10700
gene id: 1185653:BBH88_RS10700
uniprot id: A0A1C7DH70
names: Subcellular Location Annotation
messages: Cytoplasm

1185653:BBH88 RS09575
gene id: 1185653:BBH88_RS09575
uniprot id: A0A1C7DHR7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS02825
gene id: 1185653:BBH88_RS02825
uniprot id: A0A1C7DLE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS12730
gene id: 1185653:BBH88_RS12730
uniprot id: A0A1C7DG00
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS05610
gene id: 1185653:BBH88_RS05610
uniprot id: A0A1C7DJP2
names: Similarity
messages: Belongs to the UPF0342 family.

1185653:BBH88 RS14555
gene id: 1185653:BBH88_RS14555
uniprot id: A0A1C7DFK6
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS01345
gene id: 1185653:BBH88_RS01345
uniprot id: A0A1C7DCM3
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

1185653:BBH88 RS04535
gene id: 1185653:BBH88_RS04535
uniprot id: A0A1C7DK67
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

1185653:BBH88 RS08400
gene id: 1185653:BBH88_RS08400
uniprot id: A0A1C7DIQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1185653:BBH88 RS00770
gene id: 1185653:BBH88_RS00770
uniprot id: A0A1C7DD53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1185653:BBH88 RS05270
gene id: 1185653:BBH88_RS05270
uniprot id: A0A1C7DJQ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1185653:BBH88 RS11380
gene id: 1185653:BBH88_RS11380
uniprot id: A0A1C7DGV4
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS00665
gene id: 1185653:BBH88_RS00665
uniprot id: A0A1C7DCZ0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1185653:BBH88 RS16205
gene id: 1185653:BBH88_RS16205
uniprot id: A0A1C7DE08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS08700
gene id: 1185653:BBH88_RS08700
uniprot id: A0A1C7DI82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1185653:BBH88 RS07980
gene id: 1185653:BBH88_RS07980
uniprot id: A0A1C7DIL8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

1185653:BBH88 RS06170
gene id: 1185653:BBH88_RS06170
uniprot id: A0A1C7DK06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1185653:BBH88 RS07215
gene id: 1185653:BBH88_RS07215
uniprot id: A0A1C7DJI7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1185653:BBH88 RS02930
gene id: 1185653:BBH88_RS02930
uniprot id: A0A1C7DBM4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SprT family.
messages: Binds 1 zinc ion.
messages: Cytoplasm

1185653:BBH88 RS08770
gene id: 1185653:BBH88_RS08770
uniprot id: A0A1C7DHZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1185653:BBH88 RS00795
gene id: 1185653:BBH88_RS00795
uniprot id: A0A1C7DCM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1185653:BBH88 RS03565
gene id: 1185653:BBH88_RS03565
uniprot id: A0A1C7DKL2
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS14855
gene id: 1185653:BBH88_RS14855
uniprot id: A0A1C7DET5
names: Similarity
messages: Belongs to the ThiD family.

1185653:BBH88 RS15235
gene id: 1185653:BBH88_RS15235
uniprot id: A0A1C7DEQ7
names: Similarity
messages: Belongs to the peptidase M20A family.

1185653:BBH88 RS04260
gene id: 1185653:BBH88_RS04260
uniprot id: A0A1C7DK79
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

1185653:BBH88 RS12215
gene id: 1185653:BBH88_RS12215
uniprot id: A0A1C7DGB1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1185653:BBH88 RS12995
gene id: 1185653:BBH88_RS12995
uniprot id: A0A1C7DFS4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1185653:BBH88 RS07600
gene id: 1185653:BBH88_RS07600
uniprot id: A0A1C7DIL4
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1185653:BBH88 RS14795
gene id: 1185653:BBH88_RS14795
uniprot id: A0A1C7DEZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

1185653:BBH88 RS00860
gene id: 1185653:BBH88_RS00860
uniprot id: A0A1C7DD83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1185653:BBH88 RS10575
gene id: 1185653:BBH88_RS10575
uniprot id: A0A1C7DH97
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1185653:BBH88 RS04910
gene id: 1185653:BBH88_RS04910
uniprot id: A0A1C7DKE8
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1185653:BBH88 RS13450
gene id: 1185653:BBH88_RS13450
uniprot id: A0A1C7DGA0
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1185653:BBH88 RS12945
gene id: 1185653:BBH88_RS12945
uniprot id: A0A1C7DFT2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1185653:BBH88 RS12790
gene id: 1185653:BBH88_RS12790
uniprot id: A0A1C7DFZ8
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS07515
gene id: 1185653:BBH88_RS07515
uniprot id: A0A1I9W9M9
names: Function
messages: Required for transformation and DNA binding.

1185653:BBH88 RS07965
gene id: 1185653:BBH88_RS07965
uniprot id: A0A1C7DI54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1185653:BBH88 RS01080
gene id: 1185653:BBH88_RS01080
uniprot id: A0A1C7DCS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1185653:BBH88 RS01610
gene id: 1185653:BBH88_RS01610
uniprot id: A0A1C7DCH3
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1185653:BBH88 RS15280
gene id: 1185653:BBH88_RS15280
uniprot id: A0A1C7DEF7
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Consists of two distinct domains; an N-terminal heme-containing oxygen-binding domain and a C-terminal reductase domain with binding sites for FAD and NAD(P)H.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1185653:BBH88 RS07615
gene id: 1185653:BBH88_RS07615
uniprot id: A0A1C7DIS3
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

1185653:BBH88 RS07435
gene id: 1185653:BBH88_RS07435
uniprot id: A0A1C7DIQ2
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1185653:BBH88 RS06575
gene id: 1185653:BBH88_RS06575
uniprot id: A0A1C7DIS2
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1185653:BBH88 RS00345
gene id: 1185653:BBH88_RS00345
uniprot id: A0A1C7DCU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1185653:BBH88 RS10785
gene id: 1185653:BBH88_RS10785
uniprot id: A0A1C7DH58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1185653:BBH88 RS09720
gene id: 1185653:BBH88_RS09720
uniprot id: A0A1C7DHJ4
names: Similarity
messages: Belongs to the MoaD family.

1185653:BBH88 RS13785
gene id: 1185653:BBH88_RS13785
uniprot id: A0A1C7DG38
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1185653:BBH88 RS05120
gene id: 1185653:BBH88_RS05120
uniprot id: A0A1C7DK01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1185653:BBH88 RS17895
gene id: 1185653:BBH88_RS17895
uniprot id: A0A1C7DDE4
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. MtnX family.
messages: Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).

1185653:BBH88 RS04905
gene id: 1185653:BBH88_RS04905
uniprot id: A0A1C7DK38
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1185653:BBH88 RS15150
gene id: 1185653:BBH88_RS15150
uniprot id: A0A1C7DEV4
names: Similarity
messages: Belongs to the PspA/IM30 family.

1185653:BBH88 RS11775
gene id: 1185653:BBH88_RS11775
uniprot id: A0A1C7DGH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1185653:BBH88 RS12165
gene id: 1185653:BBH88_RS12165
uniprot id: A0A1C7DGV3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
messages: Cytoplasm
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.

1185653:BBH88 RS08360
gene id: 1185653:BBH88_RS08360
uniprot id: A0A1C7DIE5
names: Similarity
messages: Belongs to the GSP E family.

1185653:BBH88 RS06485
gene id: 1185653:BBH88_RS06485
uniprot id: A0A1C7DJ71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1185653:BBH88 RS02510
gene id: 1185653:BBH88_RS02510
uniprot id: A0A1C7DC22
names: Similarity
messages: Belongs to the P(II) protein family.

1185653:BBH88 RS10910
gene id: 1185653:BBH88_RS10910
uniprot id: A0A1C7DH38
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1185653:BBH88 RS14610
gene id: 1185653:BBH88_RS14610
uniprot id: A0A1C7DL70
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1185653:BBH88 RS00105
gene id: 1185653:BBH88_RS00105
uniprot id: A0A1C7DD28
names: Similarity
messages: Belongs to the DCK/DGK family.

1185653:BBH88 RS02795
gene id: 1185653:BBH88_RS02795
uniprot id: A0A1C7DBX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1185653:BBH88 RS06690
gene id: 1185653:BBH88_RS06690
uniprot id: A0A1C7DJM9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Cell membrane
messages: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1185653:BBH88 RS02175
gene id: 1185653:BBH88_RS02175
uniprot id: A0A1C7DC19
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1185653:BBH88 RS14345
gene id: 1185653:BBH88_RS14345
uniprot id: A0A1C7DFA7
names: Similarity
messages: Belongs to the acyltransferase 3 family.

1185653:BBH88 RS15270
gene id: 1185653:BBH88_RS15270
uniprot id: A0A1C7DF72
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Consists of two distinct domains; an N-terminal heme-containing oxygen-binding domain and a C-terminal reductase domain with binding sites for FAD and NAD(P)H.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1185653:BBH88 RS01530
gene id: 1185653:BBH88_RS01530
uniprot id: A0A1C7DCF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS00815
gene id: 1185653:BBH88_RS00815
uniprot id: A0A1C7DCV8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1185653:BBH88 RS11375
gene id: 1185653:BBH88_RS11375
uniprot id: A0A1C7DGV0
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS05905
gene id: 1185653:BBH88_RS05905
uniprot id: A0A1C7DJN0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1185653:BBH88 RS04500
gene id: 1185653:BBH88_RS04500
uniprot id: A0A1C7DK82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

1185653:BBH88 RS01800
gene id: 1185653:BBH88_RS01800
uniprot id: A0A1C7DC30
names: Cofactor
messages: Binds 1 FAD per subunit.

1185653:BBH88 RS00605
gene id: 1185653:BBH88_RS00605
uniprot id: A0A1C7DCU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1185653:BBH88 RS09560
gene id: 1185653:BBH88_RS09560
uniprot id: A0A1C7DHM5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS12010
gene id: 1185653:BBH88_RS12010
uniprot id: A0A1C7DGY3
names: Function
names: Similarity
messages: Belongs to the FapR family.
messages: Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism.

1185653:BBH88 RS04950
gene id: 1185653:BBH88_RS04950
uniprot id: A0A1C7DKJ7
names: Similarity
messages: Belongs to the GARS family.

1185653:BBH88 RS08040
gene id: 1185653:BBH88_RS08040
uniprot id: A0A1C7DI96
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1185653:BBH88 RS04480
gene id: 1185653:BBH88_RS04480
uniprot id: A0A1C7DKB3
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

1185653:BBH88 RS15710
gene id: 1185653:BBH88_RS15710
uniprot id: A0A1C7DEZ0
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1185653:BBH88 RS06995
gene id: 1185653:BBH88_RS06995
uniprot id: A0A1C7DIU0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1185653:BBH88 RS16100
gene id: 1185653:BBH88_RS16100
uniprot id: A0A1C7DE16
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1185653:BBH88 RS01250
gene id: 1185653:BBH88_RS01250
uniprot id: A0A1C7DCC4
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

1185653:BBH88 RS13845
gene id: 1185653:BBH88_RS13845
uniprot id: A0A1C7DFY7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1185653:BBH88 RS06350
gene id: 1185653:BBH88_RS06350
uniprot id: A0A1C7DJE3
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS08155
gene id: 1185653:BBH88_RS08155
uniprot id: A0A1C7DIB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1185653:BBH88 RS07880
gene id: 1185653:BBH88_RS07880
uniprot id: A0A1C7DIL9
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1185653:BBH88 RS07280
gene id: 1185653:BBH88_RS07280
uniprot id: A0A1C7DJB5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1185653:BBH88 RS02505
gene id: 1185653:BBH88_RS02505
uniprot id: A0A1C7DCD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS01155
gene id: 1185653:BBH88_RS01155
uniprot id: A0A1C7DCK0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1185653:BBH88 RS10530
gene id: 1185653:BBH88_RS10530
uniprot id: A0A1C7DHP6
names: Similarity
messages: Belongs to the TelA family.

1185653:BBH88 RS11845
gene id: 1185653:BBH88_RS11845
uniprot id: A0A1C7DH12
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

1185653:BBH88 RS10600
gene id: 1185653:BBH88_RS10600
uniprot id: A0A1C7DH89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

1185653:BBH88 RS07440
gene id: 1185653:BBH88_RS07440
uniprot id: A0A1C7DIU3
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1185653:BBH88 RS03980
gene id: 1185653:BBH88_RS03980
uniprot id: A0A1C7DK77
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1185653:BBH88 RS04530
gene id: 1185653:BBH88_RS04530
uniprot id: A0A1C7DK99
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1185653:BBH88 RS11650
gene id: 1185653:BBH88_RS11650
uniprot id: A0A1C7DGP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1185653:BBH88 RS11035
gene id: 1185653:BBH88_RS11035
uniprot id: A0A1C7DHM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GpsB family.
messages: Cytoplasm
messages: Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.
messages: Forms polymers through the coiled coil domains. Interacts with PBP1, MreC and EzrA.

1185653:BBH88 RS04495
gene id: 1185653:BBH88_RS04495
uniprot id: A0A1C7DK46
names: Function
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

1185653:BBH88 RS16165
gene id: 1185653:BBH88_RS16165
uniprot id: A0A1C7DEA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS04935
gene id: 1185653:BBH88_RS04935
uniprot id: A0A1C7DJR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1185653:BBH88 RS14260
gene id: 1185653:BBH88_RS14260
uniprot id: A0A1C7DFA1
names: Similarity
messages: Belongs to the CpsD/CapB family.

1185653:BBH88 RS13700
gene id: 1185653:BBH88_RS13700
uniprot id: A0A1C7DFK7
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1185653:BBH88 RS17890
gene id: 1185653:BBH88_RS17890
uniprot id: A0A1C7DD68
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO large chain family. Type IV subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P).
messages: Has no RuBP-carboxylation activity.
messages: Homodimer.

1185653:BBH88 RS03050
gene id: 1185653:BBH88_RS03050
uniprot id: A0A1C7DLD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1185653:BBH88 RS04945
gene id: 1185653:BBH88_RS04945
uniprot id: A0A1C7DJZ8
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1185653:BBH88 RS16030
gene id: 1185653:BBH88_RS16030
uniprot id: A0A1C7DEA0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1185653:BBH88 RS15630
gene id: 1185653:BBH88_RS15630
uniprot id: A0A1C7DEI4
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

1185653:BBH88 RS13400
gene id: 1185653:BBH88_RS13400
uniprot id: A0A1C7DGB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS00275
gene id: 1185653:BBH88_RS00275
uniprot id: A0A1C7DD15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1185653:BBH88 RS07805
gene id: 1185653:BBH88_RS07805
uniprot id: A0A1C7DL51
names: Similarity
messages: Belongs to the UPF0297 family.

1185653:BBH88 RS11055
gene id: 1185653:BBH88_RS11055
uniprot id: A0A1C7DGK8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecU family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation.

1185653:BBH88 RS06545
gene id: 1185653:BBH88_RS06545
uniprot id: A0A1C7DJ61
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1185653:BBH88 RS07470
gene id: 1185653:BBH88_RS07470
uniprot id: A0A1C7DIW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

1185653:BBH88 RS10560
gene id: 1185653:BBH88_RS10560
uniprot id: A0A1C7DH42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

1185653:BBH88 RS12535
gene id: 1185653:BBH88_RS12535
uniprot id: A0A1C7DGT8
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1185653:BBH88 RS09705
gene id: 1185653:BBH88_RS09705
uniprot id: A0A1C7DHQ5
names: Similarity
messages: Belongs to the citrate synthase family.

1185653:BBH88 RS07460
gene id: 1185653:BBH88_RS07460
uniprot id: A0A1C7DIF6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1185653:BBH88 RS12015
gene id: 1185653:BBH88_RS12015
uniprot id: A0A1C7DG46
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1185653:BBH88 RS11310
gene id: 1185653:BBH88_RS11310
uniprot id: A0A1C7DHA4
names: Similarity
messages: Belongs to the asparaginase 1 family.

1185653:BBH88 RS14265
gene id: 1185653:BBH88_RS14265
uniprot id: A0A1C7DFC0
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS00060
gene id: 1185653:BBH88_RS00060
uniprot id: A0A1C7DDN3
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1185653:BBH88 RS11110
gene id: 1185653:BBH88_RS11110
uniprot id: A0A1C7DH00
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1185653:BBH88 RS08540
gene id: 1185653:BBH88_RS08540
uniprot id: A0A1C7DI03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

1185653:BBH88 RS02645
gene id: 1185653:BBH88_RS02645
uniprot id: A0A1C7DBN5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1185653:BBH88 RS03410
gene id: 1185653:BBH88_RS03410
uniprot id: A0A1C7DKT3
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1185653:BBH88 RS02205
gene id: 1185653:BBH88_RS02205
uniprot id: A0A1C7DBV8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

1185653:BBH88 RS01900
gene id: 1185653:BBH88_RS01900
uniprot id: A0A1C7DC67
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1185653:BBH88 RS12735
gene id: 1185653:BBH88_RS12735
uniprot id: A0A1C7DG11
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS05760
gene id: 1185653:BBH88_RS05760
uniprot id: A0A1C7DJ55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS15210
gene id: 1185653:BBH88_RS15210
uniprot id: A0A1C7DFD7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1185653:BBH88 RS05090
gene id: 1185653:BBH88_RS05090
uniprot id: A0A1C7DK04
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1185653:BBH88 RS18275
gene id: 1185653:BBH88_RS18275
uniprot id: A0A1C7DD22
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS12315
gene id: 1185653:BBH88_RS12315
uniprot id: A0A1C7DG91
names: Similarity
messages: Belongs to the ketopantoate reductase family.

1185653:BBH88 RS18395
gene id: 1185653:BBH88_RS18395
uniprot id: A0A1C7DDP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1185653:BBH88 RS12375
gene id: 1185653:BBH88_RS12375
uniprot id: A0A1C7DGW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0298 family.
messages: Cytoplasm

1185653:BBH88 RS02830
gene id: 1185653:BBH88_RS02830
uniprot id: A0A1C7DBK6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1185653:BBH88 RS11285
gene id: 1185653:BBH88_RS11285
uniprot id: A0A1C7DGR3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1185653:BBH88 RS05960
gene id: 1185653:BBH88_RS05960
uniprot id: A0A1C7DJM0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1185653:BBH88 RS01650
gene id: 1185653:BBH88_RS01650
uniprot id: A0A1C7DCA2
names: Similarity
messages: Belongs to the peptidase S8 family.

1185653:BBH88 RS10570
gene id: 1185653:BBH88_RS10570
uniprot id: A0A1C7DHT7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1185653:BBH88 RS00775
gene id: 1185653:BBH88_RS00775
uniprot id: A0A1C7DCK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1185653:BBH88 RS03830
gene id: 1185653:BBH88_RS03830
uniprot id: A0A1C7DKG5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

1185653:BBH88 RS07645
gene id: 1185653:BBH88_RS07645
uniprot id: A0A1C7DIG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1185653:BBH88 RS14995
gene id: 1185653:BBH88_RS14995
uniprot id: A0A1C7DFC1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1185653:BBH88 RS16275
gene id: 1185653:BBH88_RS16275
uniprot id: A0A1C7DE85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.
messages: Homotetramer.

1185653:BBH88 RS07345
gene id: 1185653:BBH88_RS07345
uniprot id: A0A1C7DIF2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1185653:BBH88 RS08290
gene id: 1185653:BBH88_RS08290
uniprot id: A0A1C7DIE9
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1185653:BBH88 RS01095
gene id: 1185653:BBH88_RS01095
uniprot id: A0A1C7DCF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1185653:BBH88 RS09755
gene id: 1185653:BBH88_RS09755
uniprot id: A0A1C7DHP5
names: Similarity
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1185653:BBH88 RS14615
gene id: 1185653:BBH88_RS14615
uniprot id: A0A1C7DFJ8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1185653:BBH88 RS03235
gene id: 1185653:BBH88_RS03235
uniprot id: A0A1C7DKV6
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1185653:BBH88 RS07085
gene id: 1185653:BBH88_RS07085
uniprot id: A0A1C7DJ37
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.

1185653:BBH88 RS05915
gene id: 1185653:BBH88_RS05915
uniprot id: A0A1C7DJ42
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

1185653:BBH88 RS11745
gene id: 1185653:BBH88_RS11745
uniprot id: A0A1C7DG95
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1185653:BBH88 RS09460
gene id: 1185653:BBH88_RS09460
uniprot id: A0A1C7DI73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1185653:BBH88 RS13285
gene id: 1185653:BBH88_RS13285
uniprot id: A0A1C7DGD2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

1185653:BBH88 RS08885
gene id: 1185653:BBH88_RS08885
uniprot id: A0A1C7DHU5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1185653:BBH88 RS00075
gene id: 1185653:BBH88_RS00075
uniprot id: A0A1C7DCW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

1185653:BBH88 RS15515
gene id: 1185653:BBH88_RS15515
uniprot id: A0A1C7DEK3
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1185653:BBH88 RS00190
gene id: 1185653:BBH88_RS00190
uniprot id: A0A1C7DD20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YabA family.
messages: Interacts with both DnaA and DnaN, acting as a bridge between these two proteins.
messages: Involved in initiation control of chromosome replication.

1185653:BBH88 RS05165
gene id: 1185653:BBH88_RS05165
uniprot id: A0A1C7DJS3
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS06270
gene id: 1185653:BBH88_RS06270
uniprot id: A0A1C7DJC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
messages: Membrane

1185653:BBH88 RS07605
gene id: 1185653:BBH88_RS07605
uniprot id: A0A1C7DIR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1185653:BBH88 RS04810
gene id: 1185653:BBH88_RS04810
uniprot id: A0A1C7DJY4
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

1185653:BBH88 RS16750
gene id: 1185653:BBH88_RS16750
uniprot id: A0A1C7DDP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1185653:BBH88 RS17885
gene id: 1185653:BBH88_RS17885
uniprot id: A0A1C7DD67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylthioribose kinase family.
messages: Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.
messages: Homodimer.

1185653:BBH88 RS07120
gene id: 1185653:BBH88_RS07120
uniprot id: A0A1C7DJE7
names: Similarity
messages: Belongs to the citrate synthase family.

1185653:BBH88 RS04820
gene id: 1185653:BBH88_RS04820
uniprot id: A0A1C7DKL5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1185653:BBH88 RS00265
gene id: 1185653:BBH88_RS00265
uniprot id: A0A1C7DCT4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1185653:BBH88 RS01915
gene id: 1185653:BBH88_RS01915
uniprot id: A0A1C7DCK5
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS10165
gene id: 1185653:BBH88_RS10165
uniprot id: A0A1C7DHH3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated Cas9 family.
messages: Belongs to the CRISPR-associated protein Cas9 family. Subtype II-A subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9/crRNA/tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer; Cas9 is inactive in the absence of the 2 guide RNAs (gRNA). Cas9 recognizes the protospacer adjacent motif (PAM) in the CRISPR repeat sequences to help distinguish self versus nonself, as targets within the bacterial CRISPR locus do not have PAMs. PAM recognition is also required for catalytic activity.
messages: Has 2 endonuclease domains. The discontinuous RuvC-like domain cleaves the target DNA noncomplementary to crRNA while the HNH nuclease domain cleaves the target DNA complementary to crRNA.
messages: Monomer. Binds crRNA and tracrRNA.

1185653:BBH88 RS11125
gene id: 1185653:BBH88_RS11125
uniprot id: A0A1C7DGU1
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1185653:BBH88 RS15310
gene id: 1185653:BBH88_RS15310
uniprot id: A0A1C7DFB5
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1185653:BBH88 RS01240
gene id: 1185653:BBH88_RS01240
uniprot id: A0A1C7DCP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1185653:BBH88 RS18070
gene id: 1185653:BBH88_RS18070
uniprot id: A0A1C7DDA1
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1185653:BBH88 RS17735
gene id: 1185653:BBH88_RS17735
uniprot id: A0A1C7DDF9
names: Similarity
messages: Belongs to the peptidase S51 family.

1185653:BBH88 RS08640
gene id: 1185653:BBH88_RS08640
uniprot id: A0A1C7DI92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1185653:BBH88 RS01500
gene id: 1185653:BBH88_RS01500
uniprot id: A0A1C7DCJ3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1185653:BBH88 RS10955
gene id: 1185653:BBH88_RS10955
uniprot id: A0A1C7DGX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS12110
gene id: 1185653:BBH88_RS12110
uniprot id: A0A1C7DGG9
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

1185653:BBH88 RS08465
gene id: 1185653:BBH88_RS08465
uniprot id: A0A1C7DIP1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1185653:BBH88 RS17815
gene id: 1185653:BBH88_RS17815
uniprot id: A0A1C7DD77
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS08255
gene id: 1185653:BBH88_RS08255
uniprot id: A0A1C7DHY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS12990
gene id: 1185653:BBH88_RS12990
uniprot id: A0A1C7DG03
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1185653:BBH88 RS15605
gene id: 1185653:BBH88_RS15605
uniprot id: A0A1C7DE96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family. YeeN subfamily.
messages: Cytoplasm

1185653:BBH88 RS11910
gene id: 1185653:BBH88_RS11910
uniprot id: A0A1C7DG55
names: Similarity
messages: Belongs to the DprA/Smf family.

1185653:BBH88 RS11485
gene id: 1185653:BBH88_RS11485
uniprot id: A0A1C7DGT1
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS15880
gene id: 1185653:BBH88_RS15880
uniprot id: A0A1C7DEW7
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1185653:BBH88 RS05485
gene id: 1185653:BBH88_RS05485
uniprot id: A0A1C7DJV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS04070
gene id: 1185653:BBH88_RS04070
uniprot id: A0A1C7DJZ0
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1185653:BBH88 RS13475
gene id: 1185653:BBH88_RS13475
uniprot id: A0A1C7DFP5
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1185653:BBH88 RS08535
gene id: 1185653:BBH88_RS08535
uniprot id: A0A1C7DI98
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1185653:BBH88 RS12265
gene id: 1185653:BBH88_RS12265
uniprot id: A0A1C7DGA1
names: Similarity
messages: Belongs to the UPF0749 family.

1185653:BBH88 RS05035
gene id: 1185653:BBH88_RS05035
uniprot id: A0A1C7DJX2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1185653:BBH88 RS12305
gene id: 1185653:BBH88_RS12305
uniprot id: A0A1C7DG40
names: Function
names: Similarity
messages: Belongs to the BshC family.
messages: Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH.

1185653:BBH88 RS17310
gene id: 1185653:BBH88_RS17310
uniprot id: A0A1C7DDN5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1185653:BBH88 RS11835
gene id: 1185653:BBH88_RS11835
uniprot id: A0A1C7DH74
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1185653:BBH88 RS05530
gene id: 1185653:BBH88_RS05530
uniprot id: A0A1C7DJB0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1185653:BBH88 RS04995
gene id: 1185653:BBH88_RS04995
uniprot id: A0A1C7DJV4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1185653:BBH88 RS04265
gene id: 1185653:BBH88_RS04265
uniprot id: A0A1C7DKC4
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1185653:BBH88 RS17415
gene id: 1185653:BBH88_RS17415
uniprot id: A0A1C7DE29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.

1185653:BBH88 RS12075
gene id: 1185653:BBH88_RS12075
uniprot id: A0A1C7DGG6
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1185653:BBH88 RS08025
gene id: 1185653:BBH88_RS08025
uniprot id: A0A1C7DI29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1185653:BBH88 RS11925
gene id: 1185653:BBH88_RS11925
uniprot id: A0A1C7DGA8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1185653:BBH88 RS14940
gene id: 1185653:BBH88_RS14940
uniprot id: A0A1C7DFD1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1185653:BBH88 RS11565
gene id: 1185653:BBH88_RS11565
uniprot id: A0A1C7DHC9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1185653:BBH88 RS00855
gene id: 1185653:BBH88_RS00855
uniprot id: A0A1C7DCQ1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1185653:BBH88 RS12120
gene id: 1185653:BBH88_RS12120
uniprot id: A0A1C7DG23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS12290
gene id: 1185653:BBH88_RS12290
uniprot id: A0A1C7DFY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsL family.
messages: Cell membrane
messages: Essential cell division protein.
messages: Membrane

1185653:BBH88 RS14735
gene id: 1185653:BBH88_RS14735
uniprot id: A0A1C7DF06
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

1185653:BBH88 RS09475
gene id: 1185653:BBH88_RS09475
uniprot id: A0A1C7DHV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.

1185653:BBH88 RS16715
gene id: 1185653:BBH88_RS16715
uniprot id: A0A1C7DE03
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS11250
gene id: 1185653:BBH88_RS11250
uniprot id: A0A1C7DGY1
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1185653:BBH88 RS06155
gene id: 1185653:BBH88_RS06155
uniprot id: A0A1C7DJ68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS07970
gene id: 1185653:BBH88_RS07970
uniprot id: A0A1C7DI39
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1185653:BBH88 RS12020
gene id: 1185653:BBH88_RS12020
uniprot id: A0A1C7DG39
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1185653:BBH88 RS17490
gene id: 1185653:BBH88_RS17490
uniprot id: A0A1C7DDG6
names: Similarity
messages: Belongs to the IucA/IucC family.

1185653:BBH88 RS10595
gene id: 1185653:BBH88_RS10595
uniprot id: A0A1C7DH92
names: Similarity
messages: Belongs to the peptidase S41A family.

1185653:BBH88 RS14905
gene id: 1185653:BBH88_RS14905
uniprot id: A0A1C7DEX0
names: Subcellular Location Annotation
messages: Cell membrane

1185653:BBH88 RS08450
gene id: 1185653:BBH88_RS08450
uniprot id: A0A1C7DIA9
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1185653:BBH88 RS05285
gene id: 1185653:BBH88_RS05285
uniprot id: A0A1C7DJX4
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1185653:BBH88 RS13425
gene id: 1185653:BBH88_RS13425
uniprot id: A0A1C7DFQ5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1185653:BBH88 RS16270
gene id: 1185653:BBH88_RS16270
uniprot id: A0A1C7DE68
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

1185653:BBH88 RS00765
gene id: 1185653:BBH88_RS00765
uniprot id: A0A1C7DCW8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1185653:BBH88 RS11880
gene id: 1185653:BBH88_RS11880
uniprot id: A0A1C7DGH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor.

1185653:BBH88 RS13850
gene id: 1185653:BBH88_RS13850
uniprot id: A0A1C7DF53
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1185653:BBH88 RS03885
gene id: 1185653:BBH88_RS03885
uniprot id: A0A1C7DKJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1185653:BBH88 RS08270
gene id: 1185653:BBH88_RS08270
uniprot id: A0A1C7DI56
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1185653:BBH88 RS11100
gene id: 1185653:BBH88_RS11100
uniprot id: A0A1C7DGL4
names: Function
names: Similarity
messages: 3'-5' exonuclease.
messages: Belongs to the helicase family. DinG subfamily. Type 2 sub-subfamily.

1185653:BBH88 RS11345
gene id: 1185653:BBH88_RS11345
uniprot id: A0A1C7DGS7
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1185653:BBH88 RS10480
gene id: 1185653:BBH88_RS10480
uniprot id: A0A1C7DHQ3
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1185653:BBH88 RS14445
gene id: 1185653:BBH88_RS14445
uniprot id: A0A1C7DFS3
names: Similarity
messages: Belongs to the peptidase S66 family.

1185653:BBH88 RS09740
gene id: 1185653:BBH88_RS09740
uniprot id: A0A1C7DI27
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS17320
gene id: 1185653:BBH88_RS17320
uniprot id: A0A1C7DKN0
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1185653:BBH88 RS11140
gene id: 1185653:BBH88_RS11140
uniprot id: A0A1C7DGZ5
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

1185653:BBH88 RS05770
gene id: 1185653:BBH88_RS05770
uniprot id: A0A1C7DJL7
names: Similarity
messages: Belongs to the peptidase S9C family.

1185653:BBH88 RS05280
gene id: 1185653:BBH88_RS05280
uniprot id: A0A1C7DKE0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1185653:BBH88 RS00740
gene id: 1185653:BBH88_RS00740
uniprot id: A0A1C7DCU5
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1185653:BBH88 RS00530
gene id: 1185653:BBH88_RS00530
uniprot id: A0A1C7DCQ4
names: Similarity
messages: Belongs to the ycf81 family.

1185653:BBH88 RS07020
gene id: 1185653:BBH88_RS07020
uniprot id: A0A1C7DIM8
names: Similarity
messages: Belongs to the universal stress protein A family.

1185653:BBH88 RS07685
gene id: 1185653:BBH88_RS07685
uniprot id: A0A1C7DI84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1185653:BBH88 RS08695
gene id: 1185653:BBH88_RS08695
uniprot id: A0A1C7DHQ8
names: Similarity
messages: Belongs to the SCO1/2 family.

1185653:BBH88 RS01245
gene id: 1185653:BBH88_RS01245
uniprot id: A0A1C7DCX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1185653:BBH88 RS16420
gene id: 1185653:BBH88_RS16420
uniprot id: A0A1C7DDW3
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS00165
gene id: 1185653:BBH88_RS00165
uniprot id: A0A1C7DKT6
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1185653:BBH88 RS03640
gene id: 1185653:BBH88_RS03640
uniprot id: A0A1C7DKS1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1185653:BBH88 RS15930
gene id: 1185653:BBH88_RS15930
uniprot id: A0A1C7DEG5
names: Subcellular Location Annotation
messages: Cytoplasm

1185653:BBH88 RS06535
gene id: 1185653:BBH88_RS06535
uniprot id: A0A1C7DJ99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1185653:BBH88 RS03975
gene id: 1185653:BBH88_RS03975
uniprot id: A0A1C7DKH0
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS00630
gene id: 1185653:BBH88_RS00630
uniprot id: A0A1C7DCN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1185653:BBH88 RS07220
gene id: 1185653:BBH88_RS07220
uniprot id: A0A1C7DIZ8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1185653:BBH88 RS00840
gene id: 1185653:BBH88_RS00840
uniprot id: A0A1C7DCS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS11545
gene id: 1185653:BBH88_RS11545
uniprot id: A0A1C7DGS2
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1185653:BBH88 RS15495
gene id: 1185653:BBH88_RS15495
uniprot id: A0A1C7DEK7
names: Similarity
messages: Belongs to the peptidase S13 family.

1185653:BBH88 RS01535
gene id: 1185653:BBH88_RS01535
uniprot id: A0A1C7DC93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS00850
gene id: 1185653:BBH88_RS00850
uniprot id: A0A1C7DCQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the energy-coupling factor EcfT family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane
messages: Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.

1185653:BBH88 RS11070
gene id: 1185653:BBH88_RS11070
uniprot id: A0A1C7DGQ5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1185653:BBH88 RS06200
gene id: 1185653:BBH88_RS06200
uniprot id: A0A1C7DJD6
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1185653:BBH88 RS02345
gene id: 1185653:BBH88_RS02345
uniprot id: A0A1C7DBY2
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

1185653:BBH88 RS13670
gene id: 1185653:BBH88_RS13670
uniprot id: A0A1C7DFI4
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1185653:BBH88 RS05795
gene id: 1185653:BBH88_RS05795
uniprot id: A0A1C7DJQ0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1185653:BBH88 RS01195
gene id: 1185653:BBH88_RS01195
uniprot id: A0A1C7DCY5
names: Similarity
messages: Belongs to the FlgD family.

1185653:BBH88 RS04805
gene id: 1185653:BBH88_RS04805
uniprot id: A0A1C7DJT7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1185653:BBH88 RS07940
gene id: 1185653:BBH88_RS07940
uniprot id: A0A1C7DIF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1185653:BBH88 RS00750
gene id: 1185653:BBH88_RS00750
uniprot id: A0A1C7DCS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1185653:BBH88 RS01130
gene id: 1185653:BBH88_RS01130
uniprot id: A0A1C7DD44
names: Similarity
messages: Belongs to the bacterial flagellin family.

1185653:BBH88 RS04705
gene id: 1185653:BBH88_RS04705
uniprot id: A0A1C7DK41
names: Similarity
messages: Belongs to the transpeptidase family.

1185653:BBH88 RS01235
gene id: 1185653:BBH88_RS01235
uniprot id: A0A1C7DD16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1185653:BBH88 RS07930
gene id: 1185653:BBH88_RS07930
uniprot id: A0A1C7DIK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1185653:BBH88 RS14380
gene id: 1185653:BBH88_RS14380
uniprot id: A0A1C7DF58
names: Similarity
messages: Belongs to the peptidase S8 family.

1185653:BBH88 RS12240
gene id: 1185653:BBH88_RS12240
uniprot id: A0A1C7DFZ6
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1185653:BBH88 RS14390
gene id: 1185653:BBH88_RS14390
uniprot id: A0A1C7DFT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS07350
gene id: 1185653:BBH88_RS07350
uniprot id: A0A1C7DIY5
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1185653:BBH88 RS07755
gene id: 1185653:BBH88_RS07755
uniprot id: A0A1C7DIQ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1185653:BBH88 RS13190
gene id: 1185653:BBH88_RS13190
uniprot id: A0A1C7DGA6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system DegS/DegU, which plays an important role in the transition growth phase.

1185653:BBH88 RS08545
gene id: 1185653:BBH88_RS08545
uniprot id: A0A1C7DI41
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1185653:BBH88 RS06090
gene id: 1185653:BBH88_RS06090
uniprot id: A0A1C7DIY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS11780
gene id: 1185653:BBH88_RS11780
uniprot id: A0A1C7DGI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1185653:BBH88 RS07330
gene id: 1185653:BBH88_RS07330
uniprot id: A0A1C7DIX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

1185653:BBH88 RS02085
gene id: 1185653:BBH88_RS02085
uniprot id: A0A1C7DCM0
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1185653:BBH88 RS16310
gene id: 1185653:BBH88_RS16310
uniprot id: A0A1C7DDX9
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1185653:BBH88 RS05710
gene id: 1185653:BBH88_RS05710
uniprot id: A0A1C7DJ67
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1185653:BBH88 RS14760
gene id: 1185653:BBH88_RS14760
uniprot id: A0A1C7DL46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1185653:BBH88 RS00745
gene id: 1185653:BBH88_RS00745
uniprot id: A0A1C7DCN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1185653:BBH88 RS00615
gene id: 1185653:BBH88_RS00615
uniprot id: A0A1C7DD00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1185653:BBH88 RS15810
gene id: 1185653:BBH88_RS15810
uniprot id: A0A1C7DF23
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS14790
gene id: 1185653:BBH88_RS14790
uniprot id: A0A1C7DEP3
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1185653:BBH88 RS02545
gene id: 1185653:BBH88_RS02545
uniprot id: A0A1C7DBU5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS13830
gene id: 1185653:BBH88_RS13830
uniprot id: A0A1C7DFF8
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

1185653:BBH88 RS07205
gene id: 1185653:BBH88_RS07205
uniprot id: A0A1C7DIT8
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1185653:BBH88 RS03455
gene id: 1185653:BBH88_RS03455
uniprot id: A0A1C7DKN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS08765
gene id: 1185653:BBH88_RS08765
uniprot id: A0A1C7DHW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1185653:BBH88 RS11350
gene id: 1185653:BBH88_RS11350
uniprot id: A0A1C7DHG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

1185653:BBH88 RS03470
gene id: 1185653:BBH88_RS03470
uniprot id: A0A1C7DKU4
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1185653:BBH88 RS10410
gene id: 1185653:BBH88_RS10410
uniprot id: A0A1C7DHX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1185653:BBH88 RS12530
gene id: 1185653:BBH88_RS12530
uniprot id: A0A1C7DG51
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1185653:BBH88 RS00545
gene id: 1185653:BBH88_RS00545
uniprot id: A0A1C7DCS8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1185653:BBH88 RS11170
gene id: 1185653:BBH88_RS11170
uniprot id: A0A1C7DGZ4
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS15105
gene id: 1185653:BBH88_RS15105
uniprot id: A0A1C7DFA2
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1185653:BBH88 RS16210
gene id: 1185653:BBH88_RS16210
uniprot id: A0A1C7DE83
names: Similarity
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit G family.

1185653:BBH88 RS09690
gene id: 1185653:BBH88_RS09690
uniprot id: A0A1C7DI36
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1185653:BBH88 RS05030
gene id: 1185653:BBH88_RS05030
uniprot id: A0A1C7DK12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1185653:BBH88 RS00170
gene id: 1185653:BBH88_RS00170
uniprot id: A0A1C7DD18
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1185653:BBH88 RS15205
gene id: 1185653:BBH88_RS15205
uniprot id: A0A1C7DEP9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1185653:BBH88 RS01045
gene id: 1185653:BBH88_RS01045
uniprot id: A0A1C7DCG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

1185653:BBH88 RS07400
gene id: 1185653:BBH88_RS07400
uniprot id: A0A1C7DLH0
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1185653:BBH88 RS15255
gene id: 1185653:BBH88_RS15255
uniprot id: A0A1C7DEP1
names: Similarity
messages: Belongs to the EamA transporter family.

1185653:BBH88 RS01335
gene id: 1185653:BBH88_RS01335
uniprot id: A0A1C7DCH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS02635
gene id: 1185653:BBH88_RS02635
uniprot id: A0A1C7DC05
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1185653:BBH88 RS07035
gene id: 1185653:BBH88_RS07035
uniprot id: A0A1C7DJ12
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1185653:BBH88 RS02615
gene id: 1185653:BBH88_RS02615
uniprot id: A0A1C7DBP7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1185653:BBH88 RS11365
gene id: 1185653:BBH88_RS11365
uniprot id: A0A1C7DGG5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS11105
gene id: 1185653:BBH88_RS11105
uniprot id: A0A1C7DGJ7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1185653:BBH88 RS04765
gene id: 1185653:BBH88_RS04765
uniprot id: A0A1C7DK29
names: Similarity
messages: Belongs to the peptidase S8 family.

1185653:BBH88 RS05860
gene id: 1185653:BBH88_RS05860
uniprot id: A0A1C7DJ50
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1185653:BBH88 RS04375
gene id: 1185653:BBH88_RS04375
uniprot id: A0A1C7DKA5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1185653:BBH88 RS00280
gene id: 1185653:BBH88_RS00280
uniprot id: A0A1C7DCV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1185653:BBH88 RS00235
gene id: 1185653:BBH88_RS00235
uniprot id: A0A1C7DD11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1185653:BBH88 RS00080
gene id: 1185653:BBH88_RS00080
uniprot id: A0A1C7DCW9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1185653:BBH88 RS02640
gene id: 1185653:BBH88_RS02640
uniprot id: A0A1C7DC76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1185653:BBH88 RS06190
gene id: 1185653:BBH88_RS06190
uniprot id: A0A1C7DIW8
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. NagD family.
messages: Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro.

1185653:BBH88 RS05995
gene id: 1185653:BBH88_RS05995
uniprot id: A0A1C7DJE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1185653:BBH88 RS13220
gene id: 1185653:BBH88_RS13220
uniprot id: A0A1C7DFR1
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1185653:BBH88 RS02450
gene id: 1185653:BBH88_RS02450
uniprot id: A0A1C7DCE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS08460
gene id: 1185653:BBH88_RS08460
uniprot id: A0A1C7DIC2
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1185653:BBH88 RS16820
gene id: 1185653:BBH88_RS16820
uniprot id: A0A1C7DDS5
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS11220
gene id: 1185653:BBH88_RS11220
uniprot id: A0A1C7DGY0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1185653:BBH88 RS04920
gene id: 1185653:BBH88_RS04920
uniprot id: A0A1C7DJI0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1185653:BBH88 RS15960
gene id: 1185653:BBH88_RS15960
uniprot id: A0A1C7DE91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS02105
gene id: 1185653:BBH88_RS02105
uniprot id: A0A1C7DBX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1185653:BBH88 RS04505
gene id: 1185653:BBH88_RS04505
uniprot id: A0A1C7DKS5
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1185653:BBH88 RS05515
gene id: 1185653:BBH88_RS05515
uniprot id: A0A1C7DKC5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1185653:BBH88 RS14325
gene id: 1185653:BBH88_RS14325
uniprot id: A0A1C7DF32
names: Similarity
messages: Belongs to the peptidase S8 family.

1185653:BBH88 RS07590
gene id: 1185653:BBH88_RS07590
uniprot id: A0A1C7DIR7
names: Similarity
messages: Belongs to the UPF0758 family.

1185653:BBH88 RS07185
gene id: 1185653:BBH88_RS07185
uniprot id: A0A1C7DL61
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

1185653:BBH88 RS15420
gene id: 1185653:BBH88_RS15420
uniprot id: A0A1C7DF95
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS07405
gene id: 1185653:BBH88_RS07405
uniprot id: A0A1C7DIG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1185653:BBH88 RS00835
gene id: 1185653:BBH88_RS00835
uniprot id: A0A1C7DCQ0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1185653:BBH88 RS14485
gene id: 1185653:BBH88_RS14485
uniprot id: A0A1C7DF37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1185653:BBH88 RS02820
gene id: 1185653:BBH88_RS02820
uniprot id: A0A1C7DBT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS04565
gene id: 1185653:BBH88_RS04565
uniprot id: A0A1C7DKL3
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

1185653:BBH88 RS06175
gene id: 1185653:BBH88_RS06175
uniprot id: A0A1C7DJH8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1185653:BBH88 RS09185
gene id: 1185653:BBH88_RS09185
uniprot id: A0A1C7DI01
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

1185653:BBH88 RS03525
gene id: 1185653:BBH88_RS03525
uniprot id: A0A1C7DLA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1185653:BBH88 RS07960
gene id: 1185653:BBH88_RS07960
uniprot id: A0A1C7DIY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1185653:BBH88 RS14275
gene id: 1185653:BBH88_RS14275
uniprot id: A0A1C7DF75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LytR/CpsA/Psr (LCP) family.
messages: Cell membrane
messages: May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG).

1185653:BBH88 RS04700
gene id: 1185653:BBH88_RS04700
uniprot id: A0A1C7DK03
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1185653:BBH88 RS04065
gene id: 1185653:BBH88_RS04065
uniprot id: A0A1C7DKU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.
messages: Cytoplasm

1185653:BBH88 RS01050
gene id: 1185653:BBH88_RS01050
uniprot id: A0A1C7DCM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1185653:BBH88 RS00515
gene id: 1185653:BBH88_RS00515
uniprot id: A0A1C7DD17
names: Activity Regulation
names: Function
names: Similarity
messages: Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.

1185653:BBH88 RS01430
gene id: 1185653:BBH88_RS01430
uniprot id: A0A1C7DCE9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS01180
gene id: 1185653:BBH88_RS01180
uniprot id: A0A1C7DD26
names: Subcellular Location Annotation
messages: Cytoplasm

1185653:BBH88 RS16185
gene id: 1185653:BBH88_RS16185
uniprot id: A0A1C7DEV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS06985
gene id: 1185653:BBH88_RS06985
uniprot id: A0A1C7DJ51
names: Similarity
messages: Belongs to the peptidase S49 family.

1185653:BBH88 RS05245
gene id: 1185653:BBH88_RS05245
uniprot id: A0A1C7DJD8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1185653:BBH88 RS06250
gene id: 1185653:BBH88_RS06250
uniprot id: A0A1C7DJG3
names: Similarity
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit G family.

1185653:BBH88 RS01115
gene id: 1185653:BBH88_RS01115
uniprot id: A0A1C7DCH8
names: Similarity
messages: Belongs to the FlgM family.

1185653:BBH88 RS15330
gene id: 1185653:BBH88_RS15330
uniprot id: A0A1C7DEE7
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

1185653:BBH88 RS06805
gene id: 1185653:BBH88_RS06805
uniprot id: A0A1C7DJ86
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1185653:BBH88 RS11420
gene id: 1185653:BBH88_RS11420
uniprot id: A0A1C7DGE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

1185653:BBH88 RS13970
gene id: 1185653:BBH88_RS13970
uniprot id: A0A1C7DFF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FemABX family.
messages: Cytoplasm

1185653:BBH88 RS13465
gene id: 1185653:BBH88_RS13465
uniprot id: A0A1C7DFD0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1185653:BBH88 RS16390
gene id: 1185653:BBH88_RS16390
uniprot id: A0A1C7DE06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1185653:BBH88 RS06780
gene id: 1185653:BBH88_RS06780
uniprot id: A0A1C7DJ63
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1185653:BBH88 RS05230
gene id: 1185653:BBH88_RS05230
uniprot id: A0A1C7DKE9
names: Similarity
messages: Belongs to the UPF0374 family.

1185653:BBH88 RS02585
gene id: 1185653:BBH88_RS02585
uniprot id: A0A1C7DC86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1185653:BBH88 RS17710
gene id: 1185653:BBH88_RS17710
uniprot id: A0A1C7DDH2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1185653:BBH88 RS01370
gene id: 1185653:BBH88_RS01370
uniprot id: A0A1C7DCJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS12025
gene id: 1185653:BBH88_RS12025
uniprot id: A0A1C7DGH6
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1185653:BBH88 RS07935
gene id: 1185653:BBH88_RS07935
uniprot id: A0A1C7DIB7
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1185653:BBH88 RS16025
gene id: 1185653:BBH88_RS16025
uniprot id: A0A1C7DEB5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1185653:BBH88 RS07815
gene id: 1185653:BBH88_RS07815
uniprot id: A0A1C7DI66
names: Similarity
messages: Belongs to the UPF0473 family.

1185653:BBH88 RS06830
gene id: 1185653:BBH88_RS06830
uniprot id: A0A1C7DJ57
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1185653:BBH88 RS10995
gene id: 1185653:BBH88_RS10995
uniprot id: A0A1C7DGN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

1185653:BBH88 RS00230
gene id: 1185653:BBH88_RS00230
uniprot id: A0A1C7DCX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

1185653:BBH88 RS06055
gene id: 1185653:BBH88_RS06055
uniprot id: A0A1C7DJD9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1185653:BBH88 RS00690
gene id: 1185653:BBH88_RS00690
uniprot id: A0A1C7DCV6
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS07905
gene id: 1185653:BBH88_RS07905
uniprot id: A0A1C7DIL7
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1185653:BBH88 RS11770
gene id: 1185653:BBH88_RS11770
uniprot id: A0A1C7DGD1
names: Similarity
messages: Belongs to the peptidase M16 family.

1185653:BBH88 RS00780
gene id: 1185653:BBH88_RS00780
uniprot id: A0A1C7DCK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1185653:BBH88 RS06765
gene id: 1185653:BBH88_RS06765
uniprot id: A0A1C7DIP4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1185653:BBH88 RS13415
gene id: 1185653:BBH88_RS13415
uniprot id: A0A1C7DFE0
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1185653:BBH88 RS09200
gene id: 1185653:BBH88_RS09200
uniprot id: A0A1C7DHT6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1185653:BBH88 RS02835
gene id: 1185653:BBH88_RS02835
uniprot id: A0A1C7DBQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1185653:BBH88 RS09745
gene id: 1185653:BBH88_RS09745
uniprot id: A0A1C7DH95
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1185653:BBH88 RS07030
gene id: 1185653:BBH88_RS07030
uniprot id: A0A1C7DJ41
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1185653:BBH88 RS11900
gene id: 1185653:BBH88_RS11900
uniprot id: A0A1C7DH03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

1185653:BBH88 RS11230
gene id: 1185653:BBH88_RS11230
uniprot id: A0A1C7DGN0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1185653:BBH88 RS07770
gene id: 1185653:BBH88_RS07770
uniprot id: A0A1C7DIE1
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

1185653:BBH88 RS16180
gene id: 1185653:BBH88_RS16180
uniprot id: A0A1C7DE74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS14315
gene id: 1185653:BBH88_RS14315
uniprot id: A0A1C7DF90
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS15600
gene id: 1185653:BBH88_RS15600
uniprot id: A0A1C7DF11
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1185653:BBH88 RS08305
gene id: 1185653:BBH88_RS08305
uniprot id: A0A1C7DHX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1185653:BBH88 RS00620
gene id: 1185653:BBH88_RS00620
uniprot id: A0A1C7DD86
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1185653:BBH88 RS09995
gene id: 1185653:BBH88_RS09995
uniprot id: A0A1C7DHK1
names: Function
messages: Mediates the mercuric-dependent induction of mercury resistance operon. In the absence of mercury MerR represses transcription by binding tightly to the mer operator region; when mercury is present the dimeric complex binds a single ion and becomes a potent transcriptional activator, while remaining bound to the mer site.

1185653:BBH88 RS18320
gene id: 1185653:BBH88_RS18320
uniprot id: A0A1C7DD10
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1185653:BBH88 RS05100
gene id: 1185653:BBH88_RS05100
uniprot id: A0A1C7DJN8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1185653:BBH88 RS14670
gene id: 1185653:BBH88_RS14670
uniprot id: A0A1C7DFI2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1185653:BBH88 RS00785
gene id: 1185653:BBH88_RS00785
uniprot id: A0A1C7DCR1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1185653:BBH88 RS05125
gene id: 1185653:BBH88_RS05125
uniprot id: A0A1C7DKB1
names: Similarity
messages: Belongs to the peptidase M29 family.

1185653:BBH88 RS02680
gene id: 1185653:BBH88_RS02680
uniprot id: A0A1C7DBS7
names: Similarity
messages: Belongs to the CvfB family.

1185653:BBH88 RS11920
gene id: 1185653:BBH88_RS11920
uniprot id: A0A1C7DGJ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1185653:BBH88 RS02865
gene id: 1185653:BBH88_RS02865
uniprot id: A0A1C7DC33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1185653:BBH88 RS05115
gene id: 1185653:BBH88_RS05115
uniprot id: A0A1C7DKG8
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1185653:BBH88 RS17780
gene id: 1185653:BBH88_RS17780
uniprot id: A0A1C7DDF0
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

1185653:BBH88 RS06865
gene id: 1185653:BBH88_RS06865
uniprot id: A0A1C7DIQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1185653:BBH88 RS01150
gene id: 1185653:BBH88_RS01150
uniprot id: A0A1C7DCE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1185653:BBH88 RS06540
gene id: 1185653:BBH88_RS06540
uniprot id: A0A1C7DJ23
names: Similarity
messages: Belongs to the Dps family.

1185653:BBH88 RS14580
gene id: 1185653:BBH88_RS14580
uniprot id: A0A1C7DEY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

1185653:BBH88 RS14410
gene id: 1185653:BBH88_RS14410
uniprot id: A0A1C7DEW0
names: Similarity
messages: Belongs to the EamA transporter family.

1185653:BBH88 RS10470
gene id: 1185653:BBH88_RS10470
uniprot id: A0A1C7DHW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1185653:BBH88 RS15940
gene id: 1185653:BBH88_RS15940
uniprot id: A0A1C7DE44
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1185653:BBH88 RS07430
gene id: 1185653:BBH88_RS07430
uniprot id: A0A1C7DIL5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1185653:BBH88 RS13715
gene id: 1185653:BBH88_RS13715
uniprot id: A0A1C7DFD2
names: Function
messages: Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA.

1185653:BBH88 RS04830
gene id: 1185653:BBH88_RS04830
uniprot id: A0A1C7DKG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1185653:BBH88 RS01835
gene id: 1185653:BBH88_RS01835
uniprot id: A0A1C7DC72
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.

1185653:BBH88 RS02115
gene id: 1185653:BBH88_RS02115
uniprot id: A0A1C7DC64
names: Similarity
messages: Belongs to the UPF0178 family.

1185653:BBH88 RS13435
gene id: 1185653:BBH88_RS13435
uniprot id: A0A1C7DFI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS05880
gene id: 1185653:BBH88_RS05880
uniprot id: A0A1C7DJJ1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1185653:BBH88 RS04440
gene id: 1185653:BBH88_RS04440
uniprot id: A0A1C7DKB9
names: Similarity
messages: Belongs to the CapA family.

1185653:BBH88 RS05000
gene id: 1185653:BBH88_RS05000
uniprot id: A0A1C7DJY8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1185653:BBH88 RS08955
gene id: 1185653:BBH88_RS08955
uniprot id: A0A1C7DI13
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS12825
gene id: 1185653:BBH88_RS12825
uniprot id: A0A1C7DFP7
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1185653:BBH88 RS08210
gene id: 1185653:BBH88_RS08210
uniprot id: A0A1C7DIH5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M38 family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the hydrolytic cleavage of a subset of L-isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation.
messages: Cytoplasm

1185653:BBH88 RS02625
gene id: 1185653:BBH88_RS02625
uniprot id: A0A1C7DBT7
names: Similarity
messages: Belongs to the UPF0312 family.

1185653:BBH88 RS14955
gene id: 1185653:BBH88_RS14955
uniprot id: A0A1C7DEW2
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1185653:BBH88 RS08280
gene id: 1185653:BBH88_RS08280
uniprot id: A0A1C7DID7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS18025
gene id: 1185653:BBH88_RS18025
uniprot id: A0A1C7DDB5
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS05185
gene id: 1185653:BBH88_RS05185
uniprot id: A0A1C7DKA4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS00730
gene id: 1185653:BBH88_RS00730
uniprot id: A0A1C7DCL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1185653:BBH88 RS15450
gene id: 1185653:BBH88_RS15450
uniprot id: A0A1C7DEP2
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS12520
gene id: 1185653:BBH88_RS12520
uniprot id: A0A1C7DG01
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1185653:BBH88 RS04630
gene id: 1185653:BBH88_RS04630
uniprot id: A0A1C7DK86
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS11940
gene id: 1185653:BBH88_RS11940
uniprot id: A0A1C7DH51
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1185653:BBH88 RS14910
gene id: 1185653:BBH88_RS14910
uniprot id: A0A1C7DEZ6
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

1185653:BBH88 RS01225
gene id: 1185653:BBH88_RS01225
uniprot id: A0A1C7DCJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

1185653:BBH88 RS13315
gene id: 1185653:BBH88_RS13315
uniprot id: A0A1C7DFS7
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1185653:BBH88 RS14495
gene id: 1185653:BBH88_RS14495
uniprot id: A0A1C7DFR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1185653:BBH88 RS05015
gene id: 1185653:BBH88_RS05015
uniprot id: A0A1C7DKC8
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

1185653:BBH88 RS09985
gene id: 1185653:BBH88_RS09985
uniprot id: A0A1C7DH55
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1185653:BBH88 RS04575
gene id: 1185653:BBH88_RS04575
uniprot id: A0A1C7DJN9
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1185653:BBH88 RS01775
gene id: 1185653:BBH88_RS01775
uniprot id: A0A1C7DC87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

1185653:BBH88 RS08730
gene id: 1185653:BBH88_RS08730
uniprot id: A0A1C7DI76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
messages: Monomer.

1185653:BBH88 RS05065
gene id: 1185653:BBH88_RS05065
uniprot id: A0A1C7DK09
names: Similarity
messages: Belongs to the peptidase M29 family.

1185653:BBH88 RS12175
gene id: 1185653:BBH88_RS12175
uniprot id: A0A1C7DG06
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1185653:BBH88 RS12915
gene id: 1185653:BBH88_RS12915
uniprot id: A0A1C7DG22
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

1185653:BBH88 RS12600
gene id: 1185653:BBH88_RS12600
uniprot id: A0A1C7DGM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS08065
gene id: 1185653:BBH88_RS08065
uniprot id: A0A1C7DIW4
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1185653:BBH88 RS07015
gene id: 1185653:BBH88_RS07015
uniprot id: A0A1C7DJG5
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS11130
gene id: 1185653:BBH88_RS11130
uniprot id: A0A1C7DGW7
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1185653:BBH88 RS08320
gene id: 1185653:BBH88_RS08320
uniprot id: A0A1C7DI46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1185653:BBH88 RS10900
gene id: 1185653:BBH88_RS10900
uniprot id: A0A1C7DL79
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1185653:BBH88 RS11965
gene id: 1185653:BBH88_RS11965
uniprot id: A0A1C7DG47
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1185653:BBH88 RS11260
gene id: 1185653:BBH88_RS11260
uniprot id: A0A1C7DGI4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1185653:BBH88 RS06890
gene id: 1185653:BBH88_RS06890
uniprot id: A0A1C7DJ02
names: Function
messages: Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions.

1185653:BBH88 RS15560
gene id: 1185653:BBH88_RS15560
uniprot id: A0A1C7DEM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS05970
gene id: 1185653:BBH88_RS05970
uniprot id: A0A1C7DJ34
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1185653:BBH88 RS05840
gene id: 1185653:BBH88_RS05840
uniprot id: A0A1C7DJK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1185653:BBH88 RS15510
gene id: 1185653:BBH88_RS15510
uniprot id: A0A1C7DEH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

1185653:BBH88 RS07795
gene id: 1185653:BBH88_RS07795
uniprot id: A0A1C7DIN5
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

1185653:BBH88 RS14600
gene id: 1185653:BBH88_RS14600
uniprot id: A0A1C7DFP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1185653:BBH88 RS11890
gene id: 1185653:BBH88_RS11890
uniprot id: A0A1C7DGK7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1185653:BBH88 RS18365
gene id: 1185653:BBH88_RS18365
uniprot id: A0A1C7DCY7
names: Similarity
messages: Belongs to the ParB family.

1185653:BBH88 RS06670
gene id: 1185653:BBH88_RS06670
uniprot id: A0A1C7DJ75
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS02810
gene id: 1185653:BBH88_RS02810
uniprot id: A0A1C7DBK9
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS09445
gene id: 1185653:BBH88_RS09445
uniprot id: A0A1C7DHS6
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

1185653:BBH88 RS12970
gene id: 1185653:BBH88_RS12970
uniprot id: A0A1C7DGG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1185653:BBH88 RS03325
gene id: 1185653:BBH88_RS03325
uniprot id: A0A1C7DKC6
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS13200
gene id: 1185653:BBH88_RS13200
uniprot id: A0A1C7DFH6
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1185653:BBH88 RS03120
gene id: 1185653:BBH88_RS03120
uniprot id: A0A1C7DL22
names: Similarity
messages: Belongs to the GbsR family.

1185653:BBH88 RS13145
gene id: 1185653:BBH88_RS13145
uniprot id: A0A1C7DFV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1185653:BBH88 RS08015
gene id: 1185653:BBH88_RS08015
uniprot id: A0A1C7DIX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1185653:BBH88 RS11080
gene id: 1185653:BBH88_RS11080
uniprot id: A0A1C7DGX5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1185653:BBH88 RS14540
gene id: 1185653:BBH88_RS14540
uniprot id: A0A1C7DF29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1185653:BBH88 RS03915
gene id: 1185653:BBH88_RS03915
uniprot id: A0A1C7DKL7
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1185653:BBH88 RS11685
gene id: 1185653:BBH88_RS11685
uniprot id: A0A1C7DH40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

1185653:BBH88 RS18295
gene id: 1185653:BBH88_RS18295
uniprot id: A0A1C7DDB3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1185653:BBH88 RS07635
gene id: 1185653:BBH88_RS07635
uniprot id: A0A1C7DIS8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1185653:BBH88 RS09480
gene id: 1185653:BBH88_RS09480
uniprot id: A0A1C7DHU3
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1185653:BBH88 RS11730
gene id: 1185653:BBH88_RS11730
uniprot id: A0A1C7DGN5
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS15925
gene id: 1185653:BBH88_RS15925
uniprot id: A0A1C7DF03
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1185653:BBH88 RS08035
gene id: 1185653:BBH88_RS08035
uniprot id: A0A1C7DII8
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

1185653:BBH88 RS04050
gene id: 1185653:BBH88_RS04050
uniprot id: A0A1C7DKF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LTA synthase family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS17705
gene id: 1185653:BBH88_RS17705
uniprot id: A0A1C7DD96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1185653:BBH88 RS16575
gene id: 1185653:BBH88_RS16575
uniprot id: A0A1C7DE43
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1185653:BBH88 RS00830
gene id: 1185653:BBH88_RS00830
uniprot id: A0A1C7DCJ7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1185653:BBH88 RS00810
gene id: 1185653:BBH88_RS00810
uniprot id: A0A1C7DD95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1185653:BBH88 RS05895
gene id: 1185653:BBH88_RS05895
uniprot id: A0A1C7DJJ4
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1185653:BBH88 RS07455
gene id: 1185653:BBH88_RS07455
uniprot id: A0A1C7DJ80
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS13995
gene id: 1185653:BBH88_RS13995
uniprot id: A0A1C7DFC7
names: Similarity
messages: Belongs to the peptidase S1B family.

1185653:BBH88 RS11655
gene id: 1185653:BBH88_RS11655
uniprot id: A0A1C7DGF1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1185653:BBH88 RS14740
gene id: 1185653:BBH88_RS14740
uniprot id: A0A1C7DF27
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1185653:BBH88 RS01055
gene id: 1185653:BBH88_RS01055
uniprot id: A0A1C7DCP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1185653:BBH88 RS01585
gene id: 1185653:BBH88_RS01585
uniprot id: A0A1C7DC83
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1185653:BBH88 RS06955
gene id: 1185653:BBH88_RS06955
uniprot id: A0A1C7DJN4
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

1185653:BBH88 RS18315
gene id: 1185653:BBH88_RS18315
uniprot id: A0A1C7DD82
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1185653:BBH88 RS11210
gene id: 1185653:BBH88_RS11210
uniprot id: A0A1C7DGJ4
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.
messages: Cytoplasm

1185653:BBH88 RS15750
gene id: 1185653:BBH88_RS15750
uniprot id: A0A1C7DEF2
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS09060
gene id: 1185653:BBH88_RS09060
uniprot id: A0A1C7DHU9
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

1185653:BBH88 RS01330
gene id: 1185653:BBH88_RS01330
uniprot id: A0A1C7DCH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS00315
gene id: 1185653:BBH88_RS00315
uniprot id: A0A1C7DDC8
names: Similarity
messages: Belongs to the CarB family.

1185653:BBH88 RS07110
gene id: 1185653:BBH88_RS07110
uniprot id: A0A1C7DJK6
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

1185653:BBH88 RS06360
gene id: 1185653:BBH88_RS06360
uniprot id: A0A1C7DJ33
names: Similarity
messages: Belongs to the EamA transporter family.

1185653:BBH88 RS01230
gene id: 1185653:BBH88_RS01230
uniprot id: A0A1C7DCJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1185653:BBH88 RS09780
gene id: 1185653:BBH88_RS09780
uniprot id: A0A1C7DHK8
names: Cofactor
messages: Binds 1 FAD per subunit.

1185653:BBH88 RS08610
gene id: 1185653:BBH88_RS08610
uniprot id: A0A1C7DI79
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1185653:BBH88 RS00715
gene id: 1185653:BBH88_RS00715
uniprot id: A0A1C7DCY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1185653:BBH88 RS17690
gene id: 1185653:BBH88_RS17690
uniprot id: A0A1C7DDL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family. BdbC subfamily.
messages: Membrane

1185653:BBH88 RS00100
gene id: 1185653:BBH88_RS00100
uniprot id: A0A1C7DD33
names: Similarity
messages: Belongs to the DCK/DGK family.

1185653:BBH88 RS11735
gene id: 1185653:BBH88_RS11735
uniprot id: A0A1C7DH30
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS00705
gene id: 1185653:BBH88_RS00705
uniprot id: A0A1C7DCT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1185653:BBH88 RS16050
gene id: 1185653:BBH88_RS16050
uniprot id: A0A1C7DE28
names: Subcellular Location Annotation
messages: Cell membrane

1185653:BBH88 RS00625
gene id: 1185653:BBH88_RS00625
uniprot id: A0A1C7DCN6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

1185653:BBH88 RS14770
gene id: 1185653:BBH88_RS14770
uniprot id: A0A1C7DF22
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1185653:BBH88 RS14715
gene id: 1185653:BBH88_RS14715
uniprot id: A0A1C7DF35
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1185653:BBH88 RS08230
gene id: 1185653:BBH88_RS08230
uniprot id: A0A1C7DIE7
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS17790
gene id: 1185653:BBH88_RS17790
uniprot id: A0A1C7DE01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

1185653:BBH88 RS01840
gene id: 1185653:BBH88_RS01840
uniprot id: A0A1C7DL39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1185653:BBH88 RS09295
gene id: 1185653:BBH88_RS09295
uniprot id: A0A1C7DHW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family. Thioredoxin-coupled ArsC subfamily.
messages: Catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)].
messages: Cytoplasm

1185653:BBH88 RS15995
gene id: 1185653:BBH88_RS15995
uniprot id: A0A1C7DE37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS01210
gene id: 1185653:BBH88_RS01210
uniprot id: A0A1C7DCI7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

1185653:BBH88 RS12235
gene id: 1185653:BBH88_RS12235
uniprot id: A0A1C7DG04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1185653:BBH88 RS06795
gene id: 1185653:BBH88_RS06795
uniprot id: A0A1C7DJ58
names: Function
names: Similarity
names: Subunit
messages: Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha-keto acid in the first half-reaction.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1185653:BBH88 RS13320
gene id: 1185653:BBH88_RS13320
uniprot id: A0A1C7DFT4
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

1185653:BBH88 RS05240
gene id: 1185653:BBH88_RS05240
uniprot id: A0A1C7DK92
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1185653:BBH88 RS15475
gene id: 1185653:BBH88_RS15475
uniprot id: A0A1C7DEP4
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS07315
gene id: 1185653:BBH88_RS07315
uniprot id: A0A1C7DIS1
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS08125
gene id: 1185653:BBH88_RS08125
uniprot id: A0A1C7DI25
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS14685
gene id: 1185653:BBH88_RS14685
uniprot id: A0A1C7DF18
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1185653:BBH88 RS12435
gene id: 1185653:BBH88_RS12435
uniprot id: A0A1C7DGQ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1185653:BBH88 RS04585
gene id: 1185653:BBH88_RS04585
uniprot id: A0A1C7DK57
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

1185653:BBH88 RS02365
gene id: 1185653:BBH88_RS02365
uniprot id: A0A1C7DBT4
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS05510
gene id: 1185653:BBH88_RS05510
uniprot id: A0A1C7DJR8
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1185653:BBH88 RS06245
gene id: 1185653:BBH88_RS06245
uniprot id: A0A1C7DIV6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1185653:BBH88 RS11435
gene id: 1185653:BBH88_RS11435
uniprot id: A0A1C7DGJ0
names: Similarity
messages: Belongs to the Fur family.

1185653:BBH88 RS14625
gene id: 1185653:BBH88_RS14625
uniprot id: A0A1C7DES1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1185653:BBH88 RS08830
gene id: 1185653:BBH88_RS08830
uniprot id: A0A1C7DHY9
names: Similarity
messages: Belongs to the EamA transporter family.

1185653:BBH88 RS04280
gene id: 1185653:BBH88_RS04280
uniprot id: A0A1C7DKR0
names: Similarity
messages: Belongs to the EamA transporter family.

1185653:BBH88 RS15730
gene id: 1185653:BBH88_RS15730
uniprot id: A0A1C7DEI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS14595
gene id: 1185653:BBH88_RS14595
uniprot id: A0A1C7DF19
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1185653:BBH88 RS09540
gene id: 1185653:BBH88_RS09540
uniprot id: A0A1C7DHC6
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

1185653:BBH88 RS01850
gene id: 1185653:BBH88_RS01850
uniprot id: A0A1C7DCQ9
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1185653:BBH88 RS10750
gene id: 1185653:BBH88_RS10750
uniprot id: A0A1C7DH56
names: Similarity
messages: Belongs to the peptidase S66 family.

1185653:BBH88 RS08575
gene id: 1185653:BBH88_RS08575
uniprot id: A0A1C7DIM1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1185653:BBH88 RS13100
gene id: 1185653:BBH88_RS13100
uniprot id: A0A1C7DFP8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1185653:BBH88 RS04715
gene id: 1185653:BBH88_RS04715
uniprot id: A0A1C7DKN4
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1185653:BBH88 RS17025
gene id: 1185653:BBH88_RS17025
uniprot id: A0A1C7DEF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1185653:BBH88 RS02650
gene id: 1185653:BBH88_RS02650
uniprot id: A0A1C7DBN7
names: Similarity
messages: Belongs to the universal stress protein A family.

1185653:BBH88 RS02880
gene id: 1185653:BBH88_RS02880
uniprot id: A0A1C7DBN4
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

1185653:BBH88 RS07845
gene id: 1185653:BBH88_RS07845
uniprot id: A0A1C7DIL6
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.

1185653:BBH88 RS12070
gene id: 1185653:BBH88_RS12070
uniprot id: A0A1C7DG30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1185653:BBH88 RS16395
gene id: 1185653:BBH88_RS16395
uniprot id: A0A1C7DE54
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1185653:BBH88 RS16425
gene id: 1185653:BBH88_RS16425
uniprot id: A0A1C7DDW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1185653:BBH88 RS12565
gene id: 1185653:BBH88_RS12565
uniprot id: A0A1C7DL68
names: Function
names: Similarity
names: Subunit
messages: A non-essential component of RNA polymerase (RNAP).
messages: Belongs to the RNA polymerase subunit epsilon family.
messages: RNAP is composed of a core of 2 alpha, a beta and a beta' subunit. The core is associated with a delta subunit, and at least one of epsilon or omega. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1185653:BBH88 RS07625
gene id: 1185653:BBH88_RS07625
uniprot id: A0A1C7DIB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1185653:BBH88 RS01200
gene id: 1185653:BBH88_RS01200
uniprot id: A0A1C7DCD8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1185653:BBH88 RS14860
gene id: 1185653:BBH88_RS14860
uniprot id: A0A1C7DEX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS12285
gene id: 1185653:BBH88_RS12285
uniprot id: A0A1C7DFZ5
names: Similarity
messages: Belongs to the transpeptidase family.

1185653:BBH88 RS03935
gene id: 1185653:BBH88_RS03935
uniprot id: A0A1C7DKI0
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS15305
gene id: 1185653:BBH88_RS15305
uniprot id: A0A1C7DEN1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS11015
gene id: 1185653:BBH88_RS11015
uniprot id: A0A1C7DGR8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

1185653:BBH88 RS00600
gene id: 1185653:BBH88_RS00600
uniprot id: A0A1C7DCV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1185653:BBH88 RS11190
gene id: 1185653:BBH88_RS11190
uniprot id: A0A1C7DGV8
names: Similarity
messages: Belongs to the UPF0302 family.

1185653:BBH88 RS00360
gene id: 1185653:BBH88_RS00360
uniprot id: A0A1C7DCY3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

1185653:BBH88 RS03080
gene id: 1185653:BBH88_RS03080
uniprot id: A0A1C7DKP9
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS04975
gene id: 1185653:BBH88_RS04975
uniprot id: A0A1C7DJH0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GGGP/HepGP synthase family. Group I subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales.

1185653:BBH88 RS07725
gene id: 1185653:BBH88_RS07725
uniprot id: A0A1C7DIP9
names: Similarity
messages: Belongs to the peptidase C56 family.

1185653:BBH88 RS07485
gene id: 1185653:BBH88_RS07485
uniprot id: A0A1C7DIP2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1185653:BBH88 RS16645
gene id: 1185653:BBH88_RS16645
uniprot id: A0A1C7DEH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1185653:BBH88 RS14930
gene id: 1185653:BBH88_RS14930
uniprot id: A0A1C7DFI8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1185653:BBH88 RS11475
gene id: 1185653:BBH88_RS11475
uniprot id: A0A1C7DKV2
names: Cofactor
names: PTM
messages: Autophosphorylated.
messages: Binds 1 [4Fe-4S] cluster.

1185653:BBH88 RS11850
gene id: 1185653:BBH88_RS11850
uniprot id: A0A1C7DG73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1185653:BBH88 RS10605
gene id: 1185653:BBH88_RS10605
uniprot id: A0A1C7DGY7
names: Similarity
messages: Belongs to the UPF0346 family.

1185653:BBH88 RS00845
gene id: 1185653:BBH88_RS00845
uniprot id: A0A1C7DCL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

1185653:BBH88 RS01985
gene id: 1185653:BBH88_RS01985
uniprot id: A0A1C7DCJ5
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS04985
gene id: 1185653:BBH88_RS04985
uniprot id: A0A1C7DJY2
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1185653:BBH88 RS15555
gene id: 1185653:BBH88_RS15555
uniprot id: A0A1C7DEJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS00380
gene id: 1185653:BBH88_RS00380
uniprot id: A0A1C7DCR5
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1185653:BBH88 RS00585
gene id: 1185653:BBH88_RS00585
uniprot id: A0A1C7DCV7
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1185653:BBH88 RS09565
gene id: 1185653:BBH88_RS09565
uniprot id: A0A1C7DHQ2
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS14200
gene id: 1185653:BBH88_RS14200
uniprot id: A0A1C7DEZ9
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1185653:BBH88 RS02165
gene id: 1185653:BBH88_RS02165
uniprot id: A0A1C7DC52
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1185653:BBH88 RS02145
gene id: 1185653:BBH88_RS02145
uniprot id: A0A1C7DCG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1185653:BBH88 RS04570
gene id: 1185653:BBH88_RS04570
uniprot id: A0A1C7DJQ3
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

1185653:BBH88 RS12665
gene id: 1185653:BBH88_RS12665
uniprot id: A0A1C7DG60
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1185653:BBH88 RS14245
gene id: 1185653:BBH88_RS14245
uniprot id: A0A1C7DFR8
names: Subcellular Location Annotation
messages: Membrane

1185653:BBH88 RS10640
gene id: 1185653:BBH88_RS10640
uniprot id: A0A1C7DGS9
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1185653:BBH88 RS01660
gene id: 1185653:BBH88_RS01660
uniprot id: A0A1C7DCT7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1185653:BBH88 RS13225
gene id: 1185653:BBH88_RS13225
uniprot id: A0A1C7DFR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

1185653:BBH88 RS14745
gene id: 1185653:BBH88_RS14745
uniprot id: A0A1C7DEV3
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1185653:BBH88 RS06860
gene id: 1185653:BBH88_RS06860
uniprot id: A0A1C7DJJ9
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.

1185653:BBH88 RS02260
gene id: 1185653:BBH88_RS02260
uniprot id: A0A1C7DBU9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1185653:BBH88 RS12555
gene id: 1185653:BBH88_RS12555
uniprot id: A0A1C7DFU1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1185653:BBH88 RS19245
gene id: 1185653:BBH88_RS19245
uniprot id: A0A1C7DGI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1185653:BBH88 RS01005
gene id: 1185653:BBH88_RS01005
uniprot id: A0A1C7DCJ6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1185653:BBH88 RS08370
gene id: 1185653:BBH88_RS08370
uniprot id: A0A1C7DI34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ComGC family.
messages: Cell membrane
messages: Homodimer.
messages: Required for transformation and DNA binding.

1185653:BBH88 RS11820
gene id: 1185653:BBH88_RS11820
uniprot id: A0A1C7DGC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1185653:BBH88 RS16660
gene id: 1185653:BBH88_RS16660
uniprot id: A0A1C7DDZ5
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.