1184251:TCELL RS03320
gene id: 1184251:TCELL_RS03320
uniprot id: I3TE67
names: Similarity
messages: Belongs to the Nth/MutY family.

1184251:TCELL RS05735
gene id: 1184251:TCELL_RS05735
uniprot id: I3TFK2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1184251:TCELL RS01625
gene id: 1184251:TCELL_RS01625
uniprot id: I3TDA0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGGP/HepGP synthase family. Group II subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

1184251:TCELL RS04720
gene id: 1184251:TCELL_RS04720
uniprot id: I3TEZ5
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1184251:TCELL RS06505
gene id: 1184251:TCELL_RS06505
uniprot id: I3TG05
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1184251:TCELL RS03520
gene id: 1184251:TCELL_RS03520
uniprot id: I3TEA6
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

1184251:TCELL RS00780
gene id: 1184251:TCELL_RS00780
uniprot id: I3TCT2
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

1184251:TCELL RS03125
gene id: 1184251:TCELL_RS03125
uniprot id: I3TE33
names: Subcellular Location Annotation
messages: Membrane

1184251:TCELL RS07520
gene id: 1184251:TCELL_RS07520
uniprot id: I3TFT6
names: Similarity
messages: Belongs to the Nth/MutY family.

1184251:TCELL RS02910
gene id: 1184251:TCELL_RS02910
uniprot id: I3TDZ3
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Part of the 30S ribosomal subunit.

1184251:TCELL RS05795
gene id: 1184251:TCELL_RS05795
uniprot id: I3TFL4
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.

1184251:TCELL RS01735
gene id: 1184251:TCELL_RS01735
uniprot id: I3TDC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L24e, part of which may contact the 16S rRNA in 2 intersubunit bridges.

1184251:TCELL RS04290
gene id: 1184251:TCELL_RS04290
uniprot id: I3TEQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
messages: Belongs to the TiaS family.
messages: Cytoplasm

1184251:TCELL RS05625
gene id: 1184251:TCELL_RS05625
uniprot id: I3TFI0
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

1184251:TCELL RS05265
gene id: 1184251:TCELL_RS05265
uniprot id: I3TFA3
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

1184251:TCELL RS00935
gene id: 1184251:TCELL_RS00935
uniprot id: I3TCW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1184251:TCELL RS00850
gene id: 1184251:TCELL_RS00850
uniprot id: I3TCU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1184251:TCELL RS00225
gene id: 1184251:TCELL_RS00225
uniprot id: I3TCI0
names: Subcellular Location Annotation
messages: Membrane

1184251:TCELL RS02135
gene id: 1184251:TCELL_RS02135
uniprot id: I3TDJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase PH family. Rrp41 subfamily.
messages: Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails.
messages: Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
messages: Cytoplasm

1184251:TCELL RS04775
gene id: 1184251:TCELL_RS04775
uniprot id: I3TF06
names: Subcellular Location Annotation
messages: Membrane

1184251:TCELL RS05130
gene id: 1184251:TCELL_RS05130
uniprot id: I3TF74
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1184251:TCELL RS04160
gene id: 1184251:TCELL_RS04160
uniprot id: I3TEN3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184251:TCELL RS04365
gene id: 1184251:TCELL_RS04365
uniprot id: I3TES3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal dihydroneopterin aldolase family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD).
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184251:TCELL RS04550
gene id: 1184251:TCELL_RS04550
uniprot id: I3TEW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1184251:TCELL RS05415
gene id: 1184251:TCELL_RS05415
uniprot id: I3TFD6
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

1184251:TCELL RS02425
gene id: 1184251:TCELL_RS02425
uniprot id: I3TDQ1
names: Function
names: Similarity
messages: Belongs to the archaeal SPP-like hydrolase family.
messages: Catalyzes the dephosphorylation of 2-phosphoglycolate.

1184251:TCELL RS02385
gene id: 1184251:TCELL_RS02385
uniprot id: I3TDP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PCNA family.
messages: Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.
messages: Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
messages: Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication.

1184251:TCELL RS00860
gene id: 1184251:TCELL_RS00860
uniprot id: I3TCU9
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184251:TCELL RS05045
gene id: 1184251:TCELL_RS05045
uniprot id: I3TF57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1184251:TCELL RS00015
gene id: 1184251:TCELL_RS00015
uniprot id: I3TCE0
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

1184251:TCELL RS01290
gene id: 1184251:TCELL_RS01290
uniprot id: I3TD34
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Both the DNA unwinding and positive supercoiling activities require the cooperation of both domains. The cooperative action between the helicase-like and the topoisomerase domains is specific. The helicase-like domain probably does not directly unwind DNA but acts more likely by driving ATP-dependent conformational changes within the whole enzyme, functioning more like a protein motor. The 'latch' region of the N-terminal domain plays a regulatory role in the enzyme, repressing topoisomerase activity in the absence of ATP and therefore preventing the enzyme from acting as an ATP-independent relaxing enzyme; it also helps to coordinate nucleotide hydrolysis by the ATPase domain with the supercoiling activity of the topoisomerase domain.
messages: In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
messages: In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication.
messages: Monomer.
messages: This enzyme is the only unique feature of hyperthermophilic bacteria/archaea discovered so far. It appears to be essential for adaptation to life at high temperatures.

1184251:TCELL RS05950
gene id: 1184251:TCELL_RS05950
uniprot id: I3TFP5
names: Similarity
messages: Belongs to the thiolase-like superfamily. UPF0219 family.

1184251:TCELL RS03150
gene id: 1184251:TCELL_RS03150
uniprot id: I3TE37
names: Similarity
messages: Belongs to the archaeal riboflavin kinase family.

1184251:TCELL RS02770
gene id: 1184251:TCELL_RS02770
uniprot id: I3TDW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

1184251:TCELL RS00385
gene id: 1184251:TCELL_RS00385
uniprot id: I3TCL1
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184251:TCELL RS02610
gene id: 1184251:TCELL_RS02610
uniprot id: I3TDT7
names: Similarity
messages: Belongs to the BtpA family.

1184251:TCELL RS01570
gene id: 1184251:TCELL_RS01570
uniprot id: I3TD88
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1184251:TCELL RS01175
gene id: 1184251:TCELL_RS01175
uniprot id: I3TD11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

1184251:TCELL RS04265
gene id: 1184251:TCELL_RS04265
uniprot id: I3TEQ3
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1184251:TCELL RS05565
gene id: 1184251:TCELL_RS05565
uniprot id: I3TFG8
names: Subcellular Location Annotation
messages: Membrane

1184251:TCELL RS04000
gene id: 1184251:TCELL_RS04000
uniprot id: I3TEK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal NMN adenylyltransferase family.
messages: Cytoplasm

1184251:TCELL RS03295
gene id: 1184251:TCELL_RS03295
uniprot id: I3TE62
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS25 family.

1184251:TCELL RS06060
gene id: 1184251:TCELL_RS06060
uniprot id: I3TFR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1184251:TCELL RS04810
gene id: 1184251:TCELL_RS04810
uniprot id: I3TF13
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184251:TCELL RS01690
gene id: 1184251:TCELL_RS01690
uniprot id: I3TDB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1184251:TCELL RS06770
gene id: 1184251:TCELL_RS06770
uniprot id: I3TG54
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm

1184251:TCELL RS07040
gene id: 1184251:TCELL_RS07040
uniprot id: I3TGA8
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1184251:TCELL RS05120
gene id: 1184251:TCELL_RS05120
uniprot id: I3TF72
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1184251:TCELL RS06405
gene id: 1184251:TCELL_RS06405
uniprot id: I3TFY5
names: Subcellular Location Annotation
messages: Membrane

1184251:TCELL RS01795
gene id: 1184251:TCELL_RS01795
uniprot id: I3TDD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1184251:TCELL RS06990
gene id: 1184251:TCELL_RS06990
uniprot id: I3TG98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1184251:TCELL RS00065
gene id: 1184251:TCELL_RS00065
uniprot id: I3TCE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1184251:TCELL RS02765
gene id: 1184251:TCELL_RS02765
uniprot id: I3TDW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1184251:TCELL RS01750
gene id: 1184251:TCELL_RS01750
uniprot id: I3TDC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; contacts the 5S rRNA and probably tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1184251:TCELL RS05075
gene id: 1184251:TCELL_RS05075
uniprot id: I3TF63
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

1184251:TCELL RS03510
gene id: 1184251:TCELL_RS03510
uniprot id: I3TEA4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Binds 3 Mg(2+) cations per subunit. The strongest magnesium site (Mg1) is bound to the beta- and gamma-phosphates of ATP and four water molecules complete its coordination sphere.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184251:TCELL RS02170
gene id: 1184251:TCELL_RS02170
uniprot id: I3TDK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1184251:TCELL RS06555
gene id: 1184251:TCELL_RS06555
uniprot id: I3TG15
names: Similarity
messages: Belongs to the HypE family.

1184251:TCELL RS00645
gene id: 1184251:TCELL_RS00645
uniprot id: I3TCQ8
names: Similarity
messages: Belongs to the thymidylate kinase family.

1184251:TCELL RS06565
gene id: 1184251:TCELL_RS06565
uniprot id: I3TG17
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

1184251:TCELL RS04125
gene id: 1184251:TCELL_RS04125
uniprot id: I3TEM6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class III (archaeal) subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1184251:TCELL RS00835
gene id: 1184251:TCELL_RS00835
uniprot id: I3TCU4
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

1184251:TCELL RS02780
gene id: 1184251:TCELL_RS02780
uniprot id: I3TDW8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL18 family.

1184251:TCELL RS01715
gene id: 1184251:TCELL_RS01715
uniprot id: I3TDB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head.
messages: Part of the 30S ribosomal subunit.

1184251:TCELL RS04390
gene id: 1184251:TCELL_RS04390
uniprot id: I3TES8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1184251:TCELL RS03220
gene id: 1184251:TCELL_RS03220
uniprot id: I3TE49
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1184251:TCELL RS05685
gene id: 1184251:TCELL_RS05685
uniprot id: I3TFJ2
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1184251:TCELL RS01315
gene id: 1184251:TCELL_RS01315
uniprot id: I3TD38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1184251:TCELL RS05550
gene id: 1184251:TCELL_RS05550
uniprot id: I3TFG5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184251:TCELL RS02000
gene id: 1184251:TCELL_RS02000
uniprot id: I3TDH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1184251:TCELL RS03230
gene id: 1184251:TCELL_RS03230
uniprot id: I3TE51
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1184251:TCELL RS01455
gene id: 1184251:TCELL_RS01455
uniprot id: I3TD65
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.
messages: Belongs to the AAA ATPase family.
messages: Consists of three main regions, an N-terminal coiled-coil domain that may assist in substrate recognition, an interdomain involved in PAN hexamerization, and a C-terminal ATPase domain of the AAA type.
messages: Cytoplasm
messages: Homohexamer. The hexameric complex has a two-ring architecture resembling a top hat that caps the 20S proteasome core at one or both ends. Upon ATP-binding, the C-terminus of PAN interacts with the alpha-rings of the proteasome core by binding to the intersubunit pockets.

1184251:TCELL RS04165
gene id: 1184251:TCELL_RS04165
uniprot id: I3TEN4
names: Subcellular Location Annotation
messages: Membrane

1184251:TCELL RS06870
gene id: 1184251:TCELL_RS06870
uniprot id: I3TG74
names: Function
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

1184251:TCELL RS04510
gene id: 1184251:TCELL_RS04510
uniprot id: I3TEV2
names: Similarity
messages: Belongs to the DtxR/MntR family.

1184251:TCELL RS03055
gene id: 1184251:TCELL_RS03055
uniprot id: I3TE19
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1184251:TCELL RS02380
gene id: 1184251:TCELL_RS02380
uniprot id: I3TDP4
names: Similarity
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.

1184251:TCELL RS05475
gene id: 1184251:TCELL_RS05475
uniprot id: I3TFF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NadC/ModD family.
messages: Hexamer formed by 3 homodimers.
messages: Involved in the catabolism of quinolinic acid (QA).

1184251:TCELL RS02565
gene id: 1184251:TCELL_RS02565
uniprot id: I3TDS8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

1184251:TCELL RS04060
gene id: 1184251:TCELL_RS04060
uniprot id: I3TEL4
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1184251:TCELL RS06470
gene id: 1184251:TCELL_RS06470
uniprot id: I3TFZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta-RFA-P synthase family.
messages: Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P).
messages: Homodimer.

1184251:TCELL RS00840
gene id: 1184251:TCELL_RS00840
uniprot id: I3TCU5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcA family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: nucleolus

1184251:TCELL RS00435
gene id: 1184251:TCELL_RS00435
uniprot id: I3TCM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcS subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

1184251:TCELL RS07250
gene id: 1184251:TCELL_RS07250
uniprot id: I3TGE9
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1184251:TCELL RS04855
gene id: 1184251:TCELL_RS04855
uniprot id: I3TF22
names: Similarity
messages: Belongs to the UPF0252 family.

1184251:TCELL RS04230
gene id: 1184251:TCELL_RS04230
uniprot id: I3TEP7
names: Subcellular Location Annotation
messages: Membrane

1184251:TCELL RS02700
gene id: 1184251:TCELL_RS02700
uniprot id: I3TDV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1184251:TCELL RS02810
gene id: 1184251:TCELL_RS02810
uniprot id: I3TDX4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184251:TCELL RS01870
gene id: 1184251:TCELL_RS01870
uniprot id: I3TDE9
names: Similarity
messages: Belongs to the archease family.

1184251:TCELL RS06970
gene id: 1184251:TCELL_RS06970
uniprot id: I3TG94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1184251:TCELL RS04205
gene id: 1184251:TCELL_RS04205
uniprot id: I3TEP2
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1184251:TCELL RS01445
gene id: 1184251:TCELL_RS01445
uniprot id: I3TD63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1184251:TCELL RS06705
gene id: 1184251:TCELL_RS06705
uniprot id: I3TG44
names: Similarity
messages: Belongs to the UPF0235 family.

1184251:TCELL RS06900
gene id: 1184251:TCELL_RS06900
uniprot id: I3TG80
names: Subcellular Location Annotation
messages: Membrane

1184251:TCELL RS00870
gene id: 1184251:TCELL_RS00870
uniprot id: I3TCV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA-intron endonuclease family. Archaeal short subfamily.
messages: Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
messages: Homotetramer; although the tetramer contains four active sites, only two participate in the cleavage. Therefore, it should be considered as a dimer of dimers.

1184251:TCELL RS05745
gene id: 1184251:TCELL_RS05745
uniprot id: I3TFK4
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

1184251:TCELL RS04605
gene id: 1184251:TCELL_RS04605
uniprot id: I3TEX2
names: Subcellular Location Annotation
messages: Membrane

1184251:TCELL RS02120
gene id: 1184251:TCELL_RS02120
uniprot id: I3TDJ6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

1184251:TCELL RS06545
gene id: 1184251:TCELL_RS06545
uniprot id: I3TG13
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

1184251:TCELL RS06065
gene id: 1184251:TCELL_RS06065
uniprot id: I3TFR8
names: Subcellular Location Annotation
messages: Membrane

1184251:TCELL RS04225
gene id: 1184251:TCELL_RS04225
uniprot id: I3TEP6
names: Subcellular Location Annotation
messages: Membrane

1184251:TCELL RS00720
gene id: 1184251:TCELL_RS00720
uniprot id: I3TCS1
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184251:TCELL RS02800
gene id: 1184251:TCELL_RS02800
uniprot id: I3TDX2
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1184251:TCELL RS05850
gene id: 1184251:TCELL_RS05850
uniprot id: I3TFM5
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

1184251:TCELL RS01975
gene id: 1184251:TCELL_RS01975
uniprot id: I3TDG8
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL20 family.
messages: Part of the 50S ribosomal subunit. Binds 23S rRNA.

1184251:TCELL RS01790
gene id: 1184251:TCELL_RS01790
uniprot id: I3TDD4
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1184251:TCELL RS03575
gene id: 1184251:TCELL_RS03575
uniprot id: I3TEB7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

1184251:TCELL RS01675
gene id: 1184251:TCELL_RS01675
uniprot id: I3TDB1
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

1184251:TCELL RS00310
gene id: 1184251:TCELL_RS00310
uniprot id: I3TCJ7
names: Similarity
messages: Belongs to the TFIIB family.

1184251:TCELL RS02655
gene id: 1184251:TCELL_RS02655
uniprot id: I3TDU7
names: Similarity
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.

1184251:TCELL RS07060
gene id: 1184251:TCELL_RS07060
uniprot id: I3TGB2
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

1184251:TCELL RS02160
gene id: 1184251:TCELL_RS02160
uniprot id: I3TDK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

1184251:TCELL RS06930
gene id: 1184251:TCELL_RS06930
uniprot id: I3TG86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. Hel308 subfamily.
messages: DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.
messages: Monomer.

1184251:TCELL RS01920
gene id: 1184251:TCELL_RS01920
uniprot id: I3TDF7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184251:TCELL RS04325
gene id: 1184251:TCELL_RS04325
uniprot id: I3TER5
names: Similarity
messages: Belongs to the Nth/MutY family.

1184251:TCELL RS02350
gene id: 1184251:TCELL_RS02350
uniprot id: I3TDN8
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family.
messages: Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L-methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2).

1184251:TCELL RS03865
gene id: 1184251:TCELL_RS03865
uniprot id: I3TEH5
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1184251:TCELL RS01225
gene id: 1184251:TCELL_RS01225
uniprot id: I3TD21
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

1184251:TCELL RS02410
gene id: 1184251:TCELL_RS02410
uniprot id: I3TDP9
names: Similarity
messages: Belongs to the eIF-2-alpha family.

1184251:TCELL RS02775
gene id: 1184251:TCELL_RS02775
uniprot id: I3TDW7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.
messages: Binds 1 [3Fe-4S] cluster.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1184251:TCELL RS05995
gene id: 1184251:TCELL_RS05995
uniprot id: I3TFQ4
names: Function
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

1184251:TCELL RS06795
gene id: 1184251:TCELL_RS06795
uniprot id: I3TG59
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184251:TCELL RS06440
gene id: 1184251:TCELL_RS06440
uniprot id: I3TFZ2
names: Subcellular Location Annotation
messages: Membrane

1184251:TCELL RS03040
gene id: 1184251:TCELL_RS03040
uniprot id: I3TE16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 'phage' integrase family. XerA subfamily.
messages: Cytoplasm
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

1184251:TCELL RS01575
gene id: 1184251:TCELL_RS01575
uniprot id: I3TD89
names: Similarity
messages: Belongs to the HerA family.

1184251:TCELL RS02600
gene id: 1184251:TCELL_RS02600
uniprot id: I3TDT5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1184251:TCELL RS06325
gene id: 1184251:TCELL_RS06325
uniprot id: I3TFX0
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

1184251:TCELL RS00390
gene id: 1184251:TCELL_RS00390
uniprot id: I3TCL2
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1184251:TCELL RS02870
gene id: 1184251:TCELL_RS02870
uniprot id: I3TDY5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Forms 2 domains with an elongated structure; Rpo4 packs into the hinge region between the 2 domains.
messages: Nucleus
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo4 that extends from the main structure.

1184251:TCELL RS01065
gene id: 1184251:TCELL_RS01065
uniprot id: I3TCZ0
names: Subcellular Location Annotation
messages: Membrane

1184251:TCELL RS02720
gene id: 1184251:TCELL_RS02720
uniprot id: I3TDV7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

1184251:TCELL RS05205
gene id: 1184251:TCELL_RS05205
uniprot id: I3TF90
names: Subcellular Location Annotation
messages: Membrane

1184251:TCELL RS02570
gene id: 1184251:TCELL_RS02570
uniprot id: I3TDS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit is less well bound than the others.
messages: Nucleus
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo7 that extends from the main structure.

1184251:TCELL RS02725
gene id: 1184251:TCELL_RS02725
uniprot id: I3TDV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Participates in transcription termination.

1184251:TCELL RS00485
gene id: 1184251:TCELL_RS00485
uniprot id: I3TCM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1184251:TCELL RS05635
gene id: 1184251:TCELL_RS05635
uniprot id: I3TFI2
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

1184251:TCELL RS02140
gene id: 1184251:TCELL_RS02140
uniprot id: I3TDK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase PH family. Rrp42 subfamily.
messages: Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site.

1184251:TCELL RS02030
gene id: 1184251:TCELL_RS02030
uniprot id: I3TDH8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the methylthiotransferase family. CDKAL1 subfamily.
messages: Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.

1184251:TCELL RS02895
gene id: 1184251:TCELL_RS02895
uniprot id: I3TDZ0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.

1184251:TCELL RS02190
gene id: 1184251:TCELL_RS02190
uniprot id: I3TDK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAC-alpha family.
messages: Contacts the emerging nascent chain on the ribosome.
messages: Homodimer. Interacts with the ribosome. Binds ribosomal RNA.

1184251:TCELL RS06480
gene id: 1184251:TCELL_RS06480
uniprot id: I3TG00
names: Subcellular Location Annotation
messages: Membrane

1184251:TCELL RS04645
gene id: 1184251:TCELL_RS04645
uniprot id: I3TEY0
names: Subcellular Location Annotation
messages: Membrane

1184251:TCELL RS00775
gene id: 1184251:TCELL_RS00775
uniprot id: I3TCT1
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1184251:TCELL RS02390
gene id: 1184251:TCELL_RS02390
uniprot id: I3TDP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase small subunit family.
messages: Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1184251:TCELL RS04400
gene id: 1184251:TCELL_RS04400
uniprot id: I3TET0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1184251:TCELL RS00875
gene id: 1184251:TCELL_RS00875
uniprot id: I3TCV3
names: Similarity
messages: Belongs to the UPF0111 family.

1184251:TCELL RS07350
gene id: 1184251:TCELL_RS07350
uniprot id: I3TFU0
names: Similarity
messages: Belongs to the HerA family.

1184251:TCELL RS02450
gene id: 1184251:TCELL_RS02450
uniprot id: I3TDQ6
names: Similarity
messages: Belongs to the PGI/PMI family.

1184251:TCELL RS06030
gene id: 1184251:TCELL_RS06030
uniprot id: I3TFR1
names: Subcellular Location Annotation
messages: Membrane

1184251:TCELL RS02075
gene id: 1184251:TCELL_RS02075
uniprot id: I3TDI7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS1 family.

1184251:TCELL RS01985
gene id: 1184251:TCELL_RS01985
uniprot id: I3TDH0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1184251:TCELL RS06110
gene id: 1184251:TCELL_RS06110
uniprot id: I3TFS7
names: Similarity
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.

1184251:TCELL RS00270
gene id: 1184251:TCELL_RS00270
uniprot id: I3TCI9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the asparaginase 1 family. GatD subfamily.
messages: Heterodimer of GatD and GatE.

1184251:TCELL RS04430
gene id: 1184251:TCELL_RS04430
uniprot id: I3TET6
names: Similarity
messages: Belongs to the HypD family.

1184251:TCELL RS04600
gene id: 1184251:TCELL_RS04600
uniprot id: I3TEX1
names: Subcellular Location Annotation
messages: Membrane

1184251:TCELL RS02965
gene id: 1184251:TCELL_RS02965
uniprot id: I3TE02
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.

1184251:TCELL RS03215
gene id: 1184251:TCELL_RS03215
uniprot id: I3TE48
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1184251:TCELL RS02630
gene id: 1184251:TCELL_RS02630
uniprot id: I3TDU2
names: Subcellular Location Annotation
messages: Membrane

1184251:TCELL RS04045
gene id: 1184251:TCELL_RS04045
uniprot id: I3TEL1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1184251:TCELL RS02005
gene id: 1184251:TCELL_RS02005
uniprot id: I3TDH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. Probably involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Probably involved in E site tRNA release (By similarity). Binds directly to 23S rRNA.
messages: Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.

1184251:TCELL RS00690
gene id: 1184251:TCELL_RS00690
uniprot id: I3TCR7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL42 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1184251:TCELL RS00360
gene id: 1184251:TCELL_RS00360
uniprot id: I3TCK7
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

1184251:TCELL RS05385
gene id: 1184251:TCELL_RS05385
uniprot id: I3TFD0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

1184251:TCELL RS04190
gene id: 1184251:TCELL_RS04190
uniprot id: I3TEN9
names: Similarity
messages: Belongs to the GcvT family.

1184251:TCELL RS01960
gene id: 1184251:TCELL_RS01960
uniprot id: I3TDG5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

1184251:TCELL RS01610
gene id: 1184251:TCELL_RS01610
uniprot id: I3TD97
names: Subunit
messages: Heterodimer composed of an alpha and a beta subunit.

1184251:TCELL RS02620
gene id: 1184251:TCELL_RS02620
uniprot id: I3TDT9
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

1184251:TCELL RS04420
gene id: 1184251:TCELL_RS04420
uniprot id: I3TET4
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.

1184251:TCELL RS06275
gene id: 1184251:TCELL_RS06275
uniprot id: I3TFW1
names: Subcellular Location Annotation
messages: Membrane

1184251:TCELL RS06630
gene id: 1184251:TCELL_RS06630
uniprot id: I3TG30
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1184251:TCELL RS00350
gene id: 1184251:TCELL_RS00350
uniprot id: I3TCK5
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

1184251:TCELL RS03240
gene id: 1184251:TCELL_RS03240
uniprot id: I3TE53
names: Subcellular Location Annotation
messages: Membrane

1184251:TCELL RS05215
gene id: 1184251:TCELL_RS05215
uniprot id: I3TF92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1184251:TCELL RS02685
gene id: 1184251:TCELL_RS02685
uniprot id: I3TDV1
names: Similarity
messages: Belongs to the UPF0215 family.

1184251:TCELL RS05195
gene id: 1184251:TCELL_RS05195
uniprot id: I3TF88
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1184251:TCELL RS02615
gene id: 1184251:TCELL_RS02615
uniprot id: I3TDT8
names: Similarity
messages: Belongs to the peptidase S8 family.

1184251:TCELL RS01745
gene id: 1184251:TCELL_RS01745
uniprot id: I3TDC5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

1184251:TCELL RS02150
gene id: 1184251:TCELL_RS02150
uniprot id: I3TDK2
names: Function
messages: Probably involved in the biogenesis of the ribosome.

1184251:TCELL RS01915
gene id: 1184251:TCELL_RS01915
uniprot id: I3TDF6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184251:TCELL RS07205
gene id: 1184251:TCELL_RS07205
uniprot id: I3TGE0
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1184251:TCELL RS02155
gene id: 1184251:TCELL_RS02155
uniprot id: I3TDK3
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

1184251:TCELL RS07045
gene id: 1184251:TCELL_RS07045
uniprot id: I3TGA9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm
messages: Homotetramer.

1184251:TCELL RS00440
gene id: 1184251:TCELL_RS00440
uniprot id: I3TCM1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcL subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

1184251:TCELL RS02560
gene id: 1184251:TCELL_RS02560
uniprot id: I3TDS7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.
messages: Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

1184251:TCELL RS06175
gene id: 1184251:TCELL_RS06175
uniprot id: I3TFU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1184251:TCELL RS06575
gene id: 1184251:TCELL_RS06575
uniprot id: I3TG19
names: Function
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

1184251:TCELL RS05290
gene id: 1184251:TCELL_RS05290
uniprot id: I3TFA8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the THI4 family.
messages: Homooctamer; tetramer of dimers.
messages: Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184251:TCELL RS01780
gene id: 1184251:TCELL_RS01780
uniprot id: I3TDD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1184251:TCELL RS04980
gene id: 1184251:TCELL_RS04980
uniprot id: I3TF44
names: Similarity
messages: Belongs to the AOR/FOR family.

1184251:TCELL RS06985
gene id: 1184251:TCELL_RS06985
uniprot id: I3TG97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

1184251:TCELL RS01055
gene id: 1184251:TCELL_RS01055
uniprot id: I3TCY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1184251:TCELL RS01685
gene id: 1184251:TCELL_RS01685
uniprot id: I3TDB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29.

1184251:TCELL RS03525
gene id: 1184251:TCELL_RS03525
uniprot id: I3TEA7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

1184251:TCELL RS04015
gene id: 1184251:TCELL_RS04015
uniprot id: I3TEK5
names: Subcellular Location Annotation
messages: Membrane

1184251:TCELL RS00395
gene id: 1184251:TCELL_RS00395
uniprot id: I3TCL3
names: Similarity
messages: Belongs to the UPF0200 family.

1184251:TCELL RS03720
gene id: 1184251:TCELL_RS03720
uniprot id: I3TEE5
names: Function
names: Similarity
messages: Belongs to the TYW3 family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72.

1184251:TCELL RS03770
gene id: 1184251:TCELL_RS03770
uniprot id: I3TEF5
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1184251:TCELL RS00235
gene id: 1184251:TCELL_RS00235
uniprot id: I3TCI2
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

1184251:TCELL RS05870
gene id: 1184251:TCELL_RS05870
uniprot id: I3TFM9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

1184251:TCELL RS03420
gene id: 1184251:TCELL_RS03420
uniprot id: I3TE86
names: Domain
names: Function
names: Similarity
messages: Belongs to the Nre family.
messages: Contains a predicted C4 metal binding domain at the N-terminus, which could be a zinc finger DNA binding domain.
messages: Involved in DNA damage repair.

1184251:TCELL RS04895
gene id: 1184251:TCELL_RS04895
uniprot id: I3TF30
names: Function
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

1184251:TCELL RS02360
gene id: 1184251:TCELL_RS02360
uniprot id: I3TDP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CSL4 family.
messages: Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with an hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. Interacts with DnaG.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs.

1184251:TCELL RS01495
gene id: 1184251:TCELL_RS01495
uniprot id: I3TD73
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

1184251:TCELL RS00170
gene id: 1184251:TCELL_RS00170
uniprot id: I3TCG9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1184251:TCELL RS01510
gene id: 1184251:TCELL_RS01510
uniprot id: I3TD76
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

1184251:TCELL RS02370
gene id: 1184251:TCELL_RS02370
uniprot id: I3TDP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1184251:TCELL RS00160
gene id: 1184251:TCELL_RS00160
uniprot id: I3TCG7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1184251:TCELL RS01775
gene id: 1184251:TCELL_RS01775
uniprot id: I3TDD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1184251:TCELL RS01965
gene id: 1184251:TCELL_RS01965
uniprot id: I3TDG6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.
messages: Belongs to the ribosomal protein L31e family.

1184251:TCELL RS04985
gene id: 1184251:TCELL_RS04985
uniprot id: I3TF45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Potential transporter for phosphate.

1184251:TCELL RS01950
gene id: 1184251:TCELL_RS01950
uniprot id: I3TDG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS19 family.
messages: May be involved in maturation of the 30S ribosomal subunit.
messages: Part of the 30S ribosomal subunit.

1184251:TCELL RS00135
gene id: 1184251:TCELL_RS00135
uniprot id: I3TCG2
names: Similarity
messages: Belongs to the RuvB family.

1184251:TCELL RS03855
gene id: 1184251:TCELL_RS03855
uniprot id: I3TEH3
names: Similarity
messages: Belongs to the CutA family.

1184251:TCELL RS01535
gene id: 1184251:TCELL_RS01535
uniprot id: I3TD81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6B family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

1184251:TCELL RS02010
gene id: 1184251:TCELL_RS02010
uniprot id: I3TDH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

1184251:TCELL RS02530
gene id: 1184251:TCELL_RS02530
uniprot id: I3TDS2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184251:TCELL RS01725
gene id: 1184251:TCELL_RS01725
uniprot id: I3TDC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

1184251:TCELL RS04715
gene id: 1184251:TCELL_RS04715
uniprot id: I3TEZ4
names: Subcellular Location Annotation
messages: Membrane

1184251:TCELL RS01095
gene id: 1184251:TCELL_RS01095
uniprot id: I3TCZ6
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

1184251:TCELL RS02785
gene id: 1184251:TCELL_RS02785
uniprot id: I3TDW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1184251:TCELL RS06625
gene id: 1184251:TCELL_RS06625
uniprot id: I3TG29
names: Subcellular Location Annotation
messages: Membrane

1184251:TCELL RS07100
gene id: 1184251:TCELL_RS07100
uniprot id: I3TGC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1184251:TCELL RS05360
gene id: 1184251:TCELL_RS05360
uniprot id: I3TFC4
names: Function
messages: Catalyzes the synthesis of GMP from XMP.

1184251:TCELL RS01970
gene id: 1184251:TCELL_RS01970
uniprot id: I3TDG7
names: Function
names: Similarity
messages: Belongs to the eIF-6 family.
messages: Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.

1184251:TCELL RS03790
gene id: 1184251:TCELL_RS03790
uniprot id: I3TEF9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1184251:TCELL RS00295
gene id: 1184251:TCELL_RS00295
uniprot id: I3TCJ4
names: Function
names: Similarity
messages: Belongs to the THEP1 NTPase family.
messages: Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency.

1184251:TCELL RS05500
gene id: 1184251:TCELL_RS05500
uniprot id: I3TFF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

1184251:TCELL RS03250
gene id: 1184251:TCELL_RS03250
uniprot id: I3TE54
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

1184251:TCELL RS05450
gene id: 1184251:TCELL_RS05450
uniprot id: I3TFE3
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1184251:TCELL RS03890
gene id: 1184251:TCELL_RS03890
uniprot id: I3TEI0
names: Similarity
names: Subunit
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Homohexamer.

1184251:TCELL RS07230
gene id: 1184251:TCELL_RS07230
uniprot id: I3TGE5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1184251:TCELL RS05445
gene id: 1184251:TCELL_RS05445
uniprot id: I3TFE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1184251:TCELL RS00230
gene id: 1184251:TCELL_RS00230
uniprot id: I3TCI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1184251:TCELL RS04900
gene id: 1184251:TCELL_RS04900
uniprot id: I3TF31
names: Subcellular Location Annotation
messages: Membrane

1184251:TCELL RS01325
gene id: 1184251:TCELL_RS01325
uniprot id: I3TD40
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

1184251:TCELL RS01440
gene id: 1184251:TCELL_RS01440
uniprot id: I3TD62
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aTrm56 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs.

1184251:TCELL RS04295
gene id: 1184251:TCELL_RS04295
uniprot id: I3TEQ9
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

1184251:TCELL RS04615
gene id: 1184251:TCELL_RS04615
uniprot id: I3TEX4
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1184251:TCELL RS02950
gene id: 1184251:TCELL_RS02950
uniprot id: I3TDZ9
names: Function
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.

1184251:TCELL RS05690
gene id: 1184251:TCELL_RS05690
uniprot id: I3TFJ3
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. PoK subfamily.
messages: Phosphorylates (R)-pantoate to form (R)-4-phosphopantoate in the CoA biosynthesis pathway.

1184251:TCELL RS06445
gene id: 1184251:TCELL_RS06445
uniprot id: I3TFZ3
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1184251:TCELL RS05460
gene id: 1184251:TCELL_RS05460
uniprot id: I3TFE5
names: Subcellular Location Annotation
messages: Membrane

1184251:TCELL RS02955
gene id: 1184251:TCELL_RS02955
uniprot id: I3TE00
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

1184251:TCELL RS00320
gene id: 1184251:TCELL_RS00320
uniprot id: I3TCJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP19 family.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

1184251:TCELL RS05680
gene id: 1184251:TCELL_RS05680
uniprot id: I3TFJ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1184251:TCELL RS04875
gene id: 1184251:TCELL_RS04875
uniprot id: I3TF26
names: Subcellular Location Annotation
messages: Membrane

1184251:TCELL RS04555
gene id: 1184251:TCELL_RS04555
uniprot id: I3TEW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1184251:TCELL RS07340
gene id: 1184251:TCELL_RS07340
uniprot id: I3TFL3
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1184251:TCELL RS04020
gene id: 1184251:TCELL_RS04020
uniprot id: I3TEK6
names: Subcellular Location Annotation
messages: Membrane

1184251:TCELL RS01380
gene id: 1184251:TCELL_RS01380
uniprot id: I3TD51
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FBP aldolase/phosphatase family.
messages: Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
messages: Consists of a single catalytic domain, but remodels its active-site architecture via a large structural change to exhibit dual activities.
messages: Homooctamer; dimer of tetramers.

1184251:TCELL RS04440
gene id: 1184251:TCELL_RS04440
uniprot id: I3TET8
names: Similarity
messages: Belongs to the UPF0111 family.

1184251:TCELL RS03715
gene id: 1184251:TCELL_RS03715
uniprot id: I3TEE4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DtdA deacylase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
messages: Monomer.

1184251:TCELL RS00280
gene id: 1184251:TCELL_RS00280
uniprot id: I3TCJ1
names: Similarity
messages: Belongs to the NOP5/NOP56 family.

1184251:TCELL RS02940
gene id: 1184251:TCELL_RS02940
uniprot id: I3TDZ7
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

1184251:TCELL RS02660
gene id: 1184251:TCELL_RS02660
uniprot id: I3TDU8
names: Function
names: Similarity
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.

1184251:TCELL RS01470
gene id: 1184251:TCELL_RS01470
uniprot id: I3TD68
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeosine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184251:TCELL RS05440
gene id: 1184251:TCELL_RS05440
uniprot id: I3TFE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1184251:TCELL RS00300
gene id: 1184251:TCELL_RS00300
uniprot id: I3TCJ5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.

1184251:TCELL RS07030
gene id: 1184251:TCELL_RS07030
uniprot id: I3TGA6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable chromatin protein, binds double-strand DNA without sequence specificity. Constrains negative DNA supercoils.
messages: Belongs to the Cren7 family.
messages: Cytoplasm
messages: Methylated at multiple sites, to varying extents.
messages: Monomer.

1184251:TCELL RS02840
gene id: 1184251:TCELL_RS02840
uniprot id: I3TDX9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL24 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L14.

1184251:TCELL RS00830
gene id: 1184251:TCELL_RS00830
uniprot id: I3TCU2
names: Similarity
messages: Belongs to the UPF0273 family.

1184251:TCELL RS05990
gene id: 1184251:TCELL_RS05990
uniprot id: I3TFQ3
names: Function
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

1184251:TCELL RS05530
gene id: 1184251:TCELL_RS05530
uniprot id: I3TFG1
names: Subunit
messages: Homotetramer.

1184251:TCELL RS00095
gene id: 1184251:TCELL_RS00095
uniprot id: I3TCF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

1184251:TCELL RS04105
gene id: 1184251:TCELL_RS04105
uniprot id: I3TEM3
names: Subcellular Location Annotation
messages: Membrane

1184251:TCELL RS00130
gene id: 1184251:TCELL_RS00130
uniprot id: I3TCG1
names: Similarity
messages: Belongs to the group II decarboxylase family.

1184251:TCELL RS04385
gene id: 1184251:TCELL_RS04385
uniprot id: I3TES7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TYW1 family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe).
messages: Cytoplasm
messages: Monomer.

1184251:TCELL RS04890
gene id: 1184251:TCELL_RS04890
uniprot id: I3TF29
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1184251:TCELL RS00450
gene id: 1184251:TCELL_RS00450
uniprot id: I3TCM3
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

1184251:TCELL RS00400
gene id: 1184251:TCELL_RS00400
uniprot id: I3TCL4
names: Similarity
messages: Belongs to the UPF0201 family.

1184251:TCELL RS03165
gene id: 1184251:TCELL_RS03165
uniprot id: I3TE40
names: Subcellular Location Annotation
messages: Membrane

1184251:TCELL RS02790
gene id: 1184251:TCELL_RS02790
uniprot id: I3TDX0
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1184251:TCELL RS02095
gene id: 1184251:TCELL_RS02095
uniprot id: I3TDJ2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.

1184251:TCELL RS03805
gene id: 1184251:TCELL_RS03805
uniprot id: I3TEG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1184251:TCELL RS00550
gene id: 1184251:TCELL_RS00550
uniprot id: I3TCN8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1184251:TCELL RS01405
gene id: 1184251:TCELL_RS01405
uniprot id: I3TD56
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1184251:TCELL RS02230
gene id: 1184251:TCELL_RS02230
uniprot id: I3TDL6
names: Subcellular Location Annotation
messages: Membrane

1184251:TCELL RS06495
gene id: 1184251:TCELL_RS06495
uniprot id: I3TG03
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1184251:TCELL RS02885
gene id: 1184251:TCELL_RS02885
uniprot id: I3TDY8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

1184251:TCELL RS03225
gene id: 1184251:TCELL_RS03225
uniprot id: I3TE50
names: Subcellular Location Annotation
messages: Membrane

1184251:TCELL RS02835
gene id: 1184251:TCELL_RS02835
uniprot id: I3TDX8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

1184251:TCELL RS05005
gene id: 1184251:TCELL_RS05005
uniprot id: I3TF49
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184251:TCELL RS01365
gene id: 1184251:TCELL_RS01365
uniprot id: I3TD49
names: Similarity
messages: Belongs to the pyruvate kinase family.

1184251:TCELL RS02020
gene id: 1184251:TCELL_RS02020
uniprot id: I3TDH7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1184251:TCELL RS05535
gene id: 1184251:TCELL_RS05535
uniprot id: I3TFG2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1184251:TCELL RS00325
gene id: 1184251:TCELL_RS00325
uniprot id: I3TCK0
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family.
messages: Part of the 30S ribosomal subunit.

1184251:TCELL RS04515
gene id: 1184251:TCELL_RS04515
uniprot id: I3TEV3
names: Similarity
messages: Belongs to the glutaredoxin family.

1184251:TCELL RS02730
gene id: 1184251:TCELL_RS02730
uniprot id: I3TDV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Part of the 30S ribosomal subunit.
messages: With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits.

1184251:TCELL RS01130
gene id: 1184251:TCELL_RS01130
uniprot id: I3TD03
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.
messages: The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

1184251:TCELL RS01490
gene id: 1184251:TCELL_RS01490
uniprot id: I3TD72
names: Similarity
messages: Belongs to the HerA family.

1184251:TCELL RS01630
gene id: 1184251:TCELL_RS01630
uniprot id: I3TDA1
names: Subcellular Location Annotation
messages: Nucleus

1184251:TCELL RS06550
gene id: 1184251:TCELL_RS06550
uniprot id: I3TG14
names: Similarity
messages: Belongs to the HupF/HypC family.

1184251:TCELL RS00825
gene id: 1184251:TCELL_RS00825
uniprot id: I3TCU1
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Both the DNA unwinding and positive supercoiling activities require the cooperation of both domains. The cooperative action between the helicase-like and the topoisomerase domains is specific. The helicase-like domain probably does not directly unwind DNA but acts more likely by driving ATP-dependent conformational changes within the whole enzyme, functioning more like a protein motor. The 'latch' region of the N-terminal domain plays a regulatory role in the enzyme, repressing topoisomerase activity in the absence of ATP and therefore preventing the enzyme from acting as an ATP-independent relaxing enzyme; it also helps to coordinate nucleotide hydrolysis by the ATPase domain with the supercoiling activity of the topoisomerase domain.
messages: In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
messages: In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication.
messages: Monomer.
messages: This enzyme is the only unique feature of hyperthermophilic bacteria/archaea discovered so far. It appears to be essential for adaptation to life at high temperatures.

1184251:TCELL RS03145
gene id: 1184251:TCELL_RS03145
uniprot id: I3TE36
names: Similarity
messages: Belongs to the AOR/FOR family.

1184251:TCELL RS00695
gene id: 1184251:TCELL_RS00695
uniprot id: I3TCR8
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

1184251:TCELL RS03395
gene id: 1184251:TCELL_RS03395
uniprot id: I3TE81
names: Function
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

1184251:TCELL RS05405
gene id: 1184251:TCELL_RS05405
uniprot id: I3TFD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1184251:TCELL RS04175
gene id: 1184251:TCELL_RS04175
uniprot id: I3TEN6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1184251:TCELL RS02055
gene id: 1184251:TCELL_RS02055
uniprot id: I3TDI3
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

1184251:TCELL RS05800
gene id: 1184251:TCELL_RS05800
uniprot id: I3TFL5
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit.

1184251:TCELL RS02555
gene id: 1184251:TCELL_RS02555
uniprot id: I3TDS6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

1184251:TCELL RS05675
gene id: 1184251:TCELL_RS05675
uniprot id: I3TFJ0
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1184251:TCELL RS06365
gene id: 1184251:TCELL_RS06365
uniprot id: I3TFX7
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1184251:TCELL RS06180
gene id: 1184251:TCELL_RS06180
uniprot id: I3TFU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1184251:TCELL RS02195
gene id: 1184251:TCELL_RS02195
uniprot id: I3TDK9
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

1184251:TCELL RS02690
gene id: 1184251:TCELL_RS02690
uniprot id: I3TDV2
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

1184251:TCELL RS04360
gene id: 1184251:TCELL_RS04360
uniprot id: I3TES2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PCNA family.
messages: Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.
messages: Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
messages: Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication.

1184251:TCELL RS00330
gene id: 1184251:TCELL_RS00330
uniprot id: I3TCK1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184251:TCELL RS04460
gene id: 1184251:TCELL_RS04460
uniprot id: I3TEU2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1184251:TCELL RS06295
gene id: 1184251:TCELL_RS06295
uniprot id: I3TFW4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1184251:TCELL RS02900
gene id: 1184251:TCELL_RS02900
uniprot id: I3TDZ1
names: Similarity
messages: Belongs to the protein kinase superfamily. BUD32 family.

1184251:TCELL RS04945
gene id: 1184251:TCELL_RS04945
uniprot id: I3TF36
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

1184251:TCELL RS00285
gene id: 1184251:TCELL_RS00285
uniprot id: I3TCJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.
messages: Interacts with nop5. Component of box C/D small ribonucleoprotein (sRNP) particles that contain rpl7ae, FlpA and nop5, plus a guide RNA.
messages: Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.

1184251:TCELL RS04970
gene id: 1184251:TCELL_RS04970
uniprot id: I3TF42
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1184251:TCELL RS02050
gene id: 1184251:TCELL_RS02050
uniprot id: I3TDI2
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

1184251:TCELL RS01560
gene id: 1184251:TCELL_RS01560
uniprot id: I3TD86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1184251:TCELL RS01530
gene id: 1184251:TCELL_RS01530
uniprot id: I3TD80
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6A family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

1184251:TCELL RS02415
gene id: 1184251:TCELL_RS02415
uniprot id: I3TDQ0
names: Function
names: Similarity
messages: Belongs to the NOP10 family.
messages: Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.

1184251:TCELL RS02875
gene id: 1184251:TCELL_RS02875
uniprot id: I3TDY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal Spt4 family.
messages: Heterodimer composed of Spt4 and Spt5.
messages: Stimulates transcription elongation.

1184251:TCELL RS05785
gene id: 1184251:TCELL_RS05785
uniprot id: I3TFL2
names: Subcellular Location Annotation
messages: Membrane

1184251:TCELL RS00265
gene id: 1184251:TCELL_RS00265
uniprot id: I3TCI8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the GatB/GatE family. GatE subfamily.
messages: Heterodimer of GatD and GatE.

1184251:TCELL RS04965
gene id: 1184251:TCELL_RS04965
uniprot id: I3TF41
names: Similarity
messages: Belongs to the UPF0251 family.

1184251:TCELL RS02945
gene id: 1184251:TCELL_RS02945
uniprot id: I3TDZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTH2 family.
messages: Cytoplasm
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1184251:TCELL RS05570
gene id: 1184251:TCELL_RS05570
uniprot id: I3TFG9
names: Subcellular Location Annotation
messages: Membrane

1184251:TCELL RS05125
gene id: 1184251:TCELL_RS05125
uniprot id: I3TF73
names: Subcellular Location Annotation
messages: Membrane

1184251:TCELL RS01555
gene id: 1184251:TCELL_RS01555
uniprot id: I3TD85
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

1184251:TCELL RS04660
gene id: 1184251:TCELL_RS04660
uniprot id: I3TEY3
names: Subcellular Location Annotation
messages: Membrane

1184251:TCELL RS00665
gene id: 1184251:TCELL_RS00665
uniprot id: I3TCR2
names: Function
messages: Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of both single-stranded RNA (ssRNA) and single-stranded DNA (ssDNA). Exhibits a strong preference for ssRNA.

1184251:TCELL RS07285
gene id: 1184251:TCELL_RS07285
uniprot id: I3TD25
names: Subcellular Location Annotation
messages: Membrane

1184251:TCELL RS01120
gene id: 1184251:TCELL_RS01120
uniprot id: I3TD01
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1184251:TCELL RS00100
gene id: 1184251:TCELL_RS00100
uniprot id: I3TCF5
names: Similarity
messages: Belongs to the UPF0282 family.

1184251:TCELL RS01875
gene id: 1184251:TCELL_RS01875
uniprot id: I3TDF0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Because the Archaea possessing a type III RuBisCO are all anaerobic, it is most likely that only the carboxylase activity of RuBisCO, and not the competitive oxygenase activity (by which RuBP reacts with O(2) to form one molecule of 3-phosphoglycerate and one molecule of 2-phosphoglycolate), is biologically relevant in these strains.
messages: Belongs to the RuBisCO large chain family. Type III subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3-phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase.
messages: Homodimer or homodecamer. In contrast to form I RuBisCO, the form III RuBisCO is composed solely of large subunits.

1184251:TCELL RS03610
gene id: 1184251:TCELL_RS03610
uniprot id: I3TEC4
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1184251:TCELL RS00370
gene id: 1184251:TCELL_RS00370
uniprot id: I3TCK9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1184251:TCELL RS06120
gene id: 1184251:TCELL_RS06120
uniprot id: I3TFS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1184251:TCELL RS03835
gene id: 1184251:TCELL_RS03835
uniprot id: I3TEG9
names: Similarity
messages: Belongs to the HypE family.

1184251:TCELL RS02345
gene id: 1184251:TCELL_RS02345
uniprot id: I3TDN7
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

1184251:TCELL RS06025
gene id: 1184251:TCELL_RS06025
uniprot id: I3TFR0
names: Subcellular Location Annotation
messages: Membrane

1184251:TCELL RS05105
gene id: 1184251:TCELL_RS05105
uniprot id: I3TF69
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1184251:TCELL RS01600
gene id: 1184251:TCELL_RS01600
uniprot id: I3TD95
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

1184251:TCELL RS07360
gene id: 1184251:TCELL_RS07360
uniprot id: I3TFY7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1184251:TCELL RS00750
gene id: 1184251:TCELL_RS00750
uniprot id: I3TCS6
names: Similarity
messages: Belongs to the SUI1 family.

1184251:TCELL RS06310
gene id: 1184251:TCELL_RS06310
uniprot id: I3TFW7
names: Subunit
messages: Heterodimer composed of an alpha and a beta subunit.

1184251:TCELL RS07105
gene id: 1184251:TCELL_RS07105
uniprot id: I3TGC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1184251:TCELL RS01955
gene id: 1184251:TCELL_RS01955
uniprot id: I3TDG4
names: Similarity
messages: Belongs to the PDCD5 family.

1184251:TCELL RS03160
gene id: 1184251:TCELL_RS03160
uniprot id: I3TE39
names: Subcellular Location Annotation
messages: Membrane

1184251:TCELL RS01835
gene id: 1184251:TCELL_RS01835
uniprot id: I3TDE4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1184251:TCELL RS01890
gene id: 1184251:TCELL_RS01890
uniprot id: I3TDF2
names: Subcellular Location Annotation
messages: Membrane

1184251:TCELL RS01995
gene id: 1184251:TCELL_RS01995
uniprot id: I3TDH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SPT5 family.
messages: Belongs to the archaeal Spt5 family.
messages: Heterodimer composed of Spt4 and Spt5. Interacts with RNA polymerase (RNAP).
messages: Stimulates transcription elongation.

1184251:TCELL RS00755
gene id: 1184251:TCELL_RS00755
uniprot id: I3TCS7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1184251:TCELL RS03465
gene id: 1184251:TCELL_RS03465
uniprot id: I3TE95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Membrane

1184251:TCELL RS06840
gene id: 1184251:TCELL_RS06840
uniprot id: I3TG68
names: Similarity
messages: Belongs to the peptidase U62 family.

1184251:TCELL RS01125
gene id: 1184251:TCELL_RS01125
uniprot id: I3TD02
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycerol-1-phosphate dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
messages: Cytoplasm
messages: Homodimer.

1184251:TCELL RS05725
gene id: 1184251:TCELL_RS05725
uniprot id: I3TFK0
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer composed of an alpha and a beta subunit.
messages: Heterodimer of the IorA and IorB subunits.

1184251:TCELL RS03875
gene id: 1184251:TCELL_RS03875
uniprot id: I3TEH7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1184251:TCELL RS02855
gene id: 1184251:TCELL_RS02855
uniprot id: I3TDY2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

1184251:TCELL RS03375
gene id: 1184251:TCELL_RS03375
uniprot id: I3TE77
names: Similarity
messages: Belongs to the ZPR1 family.

1184251:TCELL RS03930
gene id: 1184251:TCELL_RS03930
uniprot id: I3TEI8
names: Similarity
messages: Belongs to the isopentenyl phosphate kinase family.

1184251:TCELL RS05485
gene id: 1184251:TCELL_RS05485
uniprot id: I3TFF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1184251:TCELL RS05605
gene id: 1184251:TCELL_RS05605
uniprot id: I3TFH6
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1184251:TCELL RS02745
gene id: 1184251:TCELL_RS02745
uniprot id: I3TDW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1184251:TCELL RS07160
gene id: 1184251:TCELL_RS07160
uniprot id: I3TGD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1184251:TCELL RS06305
gene id: 1184251:TCELL_RS06305
uniprot id: I3TFW6
names: Subunit
messages: Heterodimer composed of an alpha and a beta subunit.

1184251:TCELL RS04940
gene id: 1184251:TCELL_RS04940
uniprot id: I3TF35
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184251:TCELL RS06595
gene id: 1184251:TCELL_RS06595
uniprot id: I3TG23
names: Similarity
messages: Belongs to the HerA family.

1184251:TCELL RS06400
gene id: 1184251:TCELL_RS06400
uniprot id: I3TFY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1184251:TCELL RS05480
gene id: 1184251:TCELL_RS05480
uniprot id: I3TFF1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184251:TCELL RS01895
gene id: 1184251:TCELL_RS01895
uniprot id: I3TDF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1184251:TCELL RS05020
gene id: 1184251:TCELL_RS05020
uniprot id: I3TF51
names: Subcellular Location Annotation
messages: Encapsulin nanocompartment

1184251:TCELL RS00810
gene id: 1184251:TCELL_RS00810
uniprot id: I3TCT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Cytoplasm
messages: Functions by promoting the formation of the first peptide bond.

1184251:TCELL RS03205
gene id: 1184251:TCELL_RS03205
uniprot id: I3TE46
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1184251:TCELL RS06520
gene id: 1184251:TCELL_RS06520
uniprot id: I3TG08
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1184251:TCELL RS05115
gene id: 1184251:TCELL_RS05115
uniprot id: I3TF71
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1184251:TCELL RS01205
gene id: 1184251:TCELL_RS01205
uniprot id: I3TD17
names: Caution
names: Function
names: Similarity
messages: Belongs to the eukaryotic RecA-like protein family.
messages: Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184251:TCELL RS04180
gene id: 1184251:TCELL_RS04180
uniprot id: I3TEN7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1184251:TCELL RS03130
gene id: 1184251:TCELL_RS03130
uniprot id: I3TE34
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

1184251:TCELL RS04990
gene id: 1184251:TCELL_RS04990
uniprot id: I3TF46
names: Similarity
messages: Belongs to the UPF0111 family.

1184251:TCELL RS06655
gene id: 1184251:TCELL_RS06655
uniprot id: I3TG34
names: Subcellular Location Annotation
messages: Membrane

1184251:TCELL RS00745
gene id: 1184251:TCELL_RS00745
uniprot id: I3TCS5
names: Caution
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

1184251:TCELL RS03195
gene id: 1184251:TCELL_RS03195
uniprot id: I3TE44
names: Similarity
messages: Belongs to the complex I 49 kDa subunit family.

1184251:TCELL RS00620
gene id: 1184251:TCELL_RS00620
uniprot id: I3TCQ2
names: Function
names: Similarity
messages: Belongs to the FAU-1 family.
messages: Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences.

1184251:TCELL RS03600
gene id: 1184251:TCELL_RS03600
uniprot id: I3TEC2
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

1184251:TCELL RS05825
gene id: 1184251:TCELL_RS05825
uniprot id: I3TFM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

1184251:TCELL RS04975
gene id: 1184251:TCELL_RS04975
uniprot id: I3TF43
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1184251:TCELL RS01740
gene id: 1184251:TCELL_RS01740
uniprot id: I3TDC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: Located at the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1184251:TCELL RS03355
gene id: 1184251:TCELL_RS03355
uniprot id: I3TE73
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1184251:TCELL RS01480
gene id: 1184251:TCELL_RS01480
uniprot id: I3TD70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo8 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

1184251:TCELL RS01180
gene id: 1184251:TCELL_RS01180
uniprot id: I3TD12
names: Similarity
messages: Belongs to the peptidase S8 family.