1167006:UWK RS09480
gene id: 1167006:UWK_RS09480
uniprot id: M1NFN5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1167006:UWK RS13275
gene id: 1167006:UWK_RS13275
uniprot id: M1NHZ3
names: Similarity
messages: Belongs to the FeoA family.

1167006:UWK RS06570
gene id: 1167006:UWK_RS06570
uniprot id: M1PN62
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS05560
gene id: 1167006:UWK_RS05560
uniprot id: M1P7K8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1167006:UWK RS16330
gene id: 1167006:UWK_RS16330
uniprot id: M1NJR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1167006:UWK RS10225
gene id: 1167006:UWK_RS10225
uniprot id: M1PG01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1167006:UWK RS04290
gene id: 1167006:UWK_RS04290
uniprot id: M1PCF7
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1167006:UWK RS04170
gene id: 1167006:UWK_RS04170
uniprot id: M1PCD3
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

1167006:UWK RS10045
gene id: 1167006:UWK_RS10045
uniprot id: M1NFY7
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1167006:UWK RS17125
gene id: 1167006:UWK_RS17125
uniprot id: M1NK69
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1167006:UWK RS09160
gene id: 1167006:UWK_RS09160
uniprot id: M1NFF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1167006:UWK RS10280
gene id: 1167006:UWK_RS10280
uniprot id: M1PG11
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1167006:UWK RS01205
gene id: 1167006:UWK_RS01205
uniprot id: M1NZX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1167006:UWK RS16665
gene id: 1167006:UWK_RS16665
uniprot id: M1P8T0
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1167006:UWK RS12465
gene id: 1167006:UWK_RS12465
uniprot id: M1PBP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1167006:UWK RS17705
gene id: 1167006:UWK_RS17705
uniprot id: M1NKG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1167006:UWK RS04165
gene id: 1167006:UWK_RS04165
uniprot id: M1NC93
names: Similarity
messages: Belongs to the LarC family.

1167006:UWK RS08135
gene id: 1167006:UWK_RS08135
uniprot id: M1PEQ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1167006:UWK RS05800
gene id: 1167006:UWK_RS05800
uniprot id: M1PMQ8
names: Similarity
messages: Belongs to the peptidase A31 family.

1167006:UWK RS17520
gene id: 1167006:UWK_RS17520
uniprot id: M1NKE0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1167006:UWK RS07480
gene id: 1167006:UWK_RS07480
uniprot id: M1NEE0
names: Subcellular Location Annotation
messages: Mitochondrion

1167006:UWK RS00210
gene id: 1167006:UWK_RS00210
uniprot id: M1PA06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

1167006:UWK RS08030
gene id: 1167006:UWK_RS08030
uniprot id: M1NEP0
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1167006:UWK RS01165
gene id: 1167006:UWK_RS01165
uniprot id: M1PAJ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1167006:UWK RS10105
gene id: 1167006:UWK_RS10105
uniprot id: M1PAB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1167006:UWK RS08425
gene id: 1167006:UWK_RS08425
uniprot id: M1P442
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1167006:UWK RS16115
gene id: 1167006:UWK_RS16115
uniprot id: M1PJP2
names: Similarity
messages: Belongs to the UPF0047 family.

1167006:UWK RS17815
gene id: 1167006:UWK_RS17815
uniprot id: M1NKI4
names: Similarity
messages: Belongs to the HsdR family.

1167006:UWK RS14470
gene id: 1167006:UWK_RS14470
uniprot id: M1PT08
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1167006:UWK RS13770
gene id: 1167006:UWK_RS13770
uniprot id: M1P754
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1167006:UWK RS16935
gene id: 1167006:UWK_RS16935
uniprot id: M1PED1
names: Similarity
messages: Belongs to the peptidase S41A family.

1167006:UWK RS05630
gene id: 1167006:UWK_RS05630
uniprot id: M1PMM1
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1167006:UWK RS05145
gene id: 1167006:UWK_RS05145
uniprot id: M1NCX3
names: Function
names: Similarity
messages: Belongs to the acetyltransferase family. EctA subfamily.
messages: Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.

1167006:UWK RS01955
gene id: 1167006:UWK_RS01955
uniprot id: M1PB47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1167006:UWK RS04520
gene id: 1167006:UWK_RS04520
uniprot id: M1P1X3
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

1167006:UWK RS07440
gene id: 1167006:UWK_RS07440
uniprot id: M1PNR8
names: Similarity
messages: Belongs to the Fur family.

1167006:UWK RS02320
gene id: 1167006:UWK_RS02320
uniprot id: M1PBB5
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1167006:UWK RS02740
gene id: 1167006:UWK_RS02740
uniprot id: M1P609
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1167006:UWK RS00860
gene id: 1167006:UWK_RS00860
uniprot id: M1P4W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1167006:UWK RS17895
gene id: 1167006:UWK_RS17895
uniprot id: M1NKK0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1167006:UWK RS04490
gene id: 1167006:UWK_RS04490
uniprot id: M1P701
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS03005
gene id: 1167006:UWK_RS03005
uniprot id: M1P0X2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1167006:UWK RS17360
gene id: 1167006:UWK_RS17360
uniprot id: M1PUL9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1167006:UWK RS07625
gene id: 1167006:UWK_RS07625
uniprot id: M1P3P7
names: Function
names: Similarity
messages: Belongs to the PhnJ family.
messages: Catalyzes the breakage of the C-P bond in alpha-D-ribose 1-methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose.

1167006:UWK RS16850
gene id: 1167006:UWK_RS16850
uniprot id: M1PK49
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1167006:UWK RS11170
gene id: 1167006:UWK_RS11170
uniprot id: M1P5L7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1167006:UWK RS03995
gene id: 1167006:UWK_RS03995
uniprot id: M1P6N1
names: Similarity
messages: Belongs to the SfsA family.

1167006:UWK RS17670
gene id: 1167006:UWK_RS17670
uniprot id: M1PEV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1167006:UWK RS01000
gene id: 1167006:UWK_RS01000
uniprot id: M1NAA2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1167006:UWK RS17875
gene id: 1167006:UWK_RS17875
uniprot id: M1PKS6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1167006:UWK RS17445
gene id: 1167006:UWK_RS17445
uniprot id: M1NKC8
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS09085
gene id: 1167006:UWK_RS09085
uniprot id: M1P4H1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1167006:UWK RS03050
gene id: 1167006:UWK_RS03050
uniprot id: M1P663
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

1167006:UWK RS13010
gene id: 1167006:UWK_RS13010
uniprot id: M1PC02
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

1167006:UWK RS06810
gene id: 1167006:UWK_RS06810
uniprot id: M1PE03
names: Similarity
messages: Belongs to the AOR/FOR family.

1167006:UWK RS04245
gene id: 1167006:UWK_RS04245
uniprot id: M1PCE7
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS10150
gene id: 1167006:UWK_RS10150
uniprot id: M1PFY7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1167006:UWK RS02680
gene id: 1167006:UWK_RS02680
uniprot id: M1PKV4
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1167006:UWK RS10530
gene id: 1167006:UWK_RS10530
uniprot id: M1PG69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

1167006:UWK RS16045
gene id: 1167006:UWK_RS16045
uniprot id: M1PTT0
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1167006:UWK RS12080
gene id: 1167006:UWK_RS12080
uniprot id: M1P6C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1167006:UWK RS17700
gene id: 1167006:UWK_RS17700
uniprot id: M1P9F7
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS02180
gene id: 1167006:UWK_RS02180
uniprot id: M1P5R9
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS06690
gene id: 1167006:UWK_RS06690
uniprot id: M1P8B4
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1167006:UWK RS07025
gene id: 1167006:UWK_RS07025
uniprot id: M1PE55
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1167006:UWK RS12845
gene id: 1167006:UWK_RS12845
uniprot id: M1P6P4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

1167006:UWK RS01765
gene id: 1167006:UWK_RS01765
uniprot id: M1P5H7
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

1167006:UWK RS08300
gene id: 1167006:UWK_RS08300
uniprot id: M1P416
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1167006:UWK RS00075
gene id: 1167006:UWK_RS00075
uniprot id: M1P9Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1167006:UWK RS11660
gene id: 1167006:UWK_RS11660
uniprot id: M1PB66
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1167006:UWK RS16550
gene id: 1167006:UWK_RS16550
uniprot id: M1PE49
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1167006:UWK RS14645
gene id: 1167006:UWK_RS14645
uniprot id: M1PD11
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

1167006:UWK RS18025
gene id: 1167006:UWK_RS18025
uniprot id: M1NZY7
names: Similarity
messages: Belongs to the bacterial secretin family.

1167006:UWK RS07365
gene id: 1167006:UWK_RS07365
uniprot id: M1PNQ5
names: Similarity
messages: Belongs to the DEAD box helicase family.

1167006:UWK RS13565
gene id: 1167006:UWK_RS13565
uniprot id: M1PSE2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

1167006:UWK RS00050
gene id: 1167006:UWK_RS00050
uniprot id: M1P9Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1167006:UWK RS05010
gene id: 1167006:UWK_RS05010
uniprot id: M1P264
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS05160
gene id: 1167006:UWK_RS05160
uniprot id: M1NCX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1167006:UWK RS11530
gene id: 1167006:UWK_RS11530
uniprot id: M1PR51
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1167006:UWK RS03425
gene id: 1167006:UWK_RS03425
uniprot id: M1PBW3
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1167006:UWK RS14950
gene id: 1167006:UWK_RS14950
uniprot id: M1P7U9
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1167006:UWK RS02455
gene id: 1167006:UWK_RS02455
uniprot id: M1PKR4
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1167006:UWK RS03490
gene id: 1167006:UWK_RS03490
uniprot id: M1P161
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1167006:UWK RS12410
gene id: 1167006:UWK_RS12410
uniprot id: M1PRR8
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1167006:UWK RS10870
gene id: 1167006:UWK_RS10870
uniprot id: M1P5F9
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1167006:UWK RS18360
gene id: 1167006:UWK_RS18360
uniprot id: M1P3L2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1167006:UWK RS04875
gene id: 1167006:UWK_RS04875
uniprot id: M1PCT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1167006:UWK RS07095
gene id: 1167006:UWK_RS07095
uniprot id: M1PNK5
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1167006:UWK RS15710
gene id: 1167006:UWK_RS15710
uniprot id: M1P882
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1167006:UWK RS07700
gene id: 1167006:UWK_RS07700
uniprot id: M1P3Q9
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS13270
gene id: 1167006:UWK_RS13270
uniprot id: M1P6W8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1167006:UWK RS13595
gene id: 1167006:UWK_RS13595
uniprot id: M1PCC9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1167006:UWK RS00595
gene id: 1167006:UWK_RS00595
uniprot id: M1NA21
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS02580
gene id: 1167006:UWK_RS02580
uniprot id: M1P0Q6
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1167006:UWK RS10260
gene id: 1167006:UWK_RS10260
uniprot id: M1PQD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1167006:UWK RS04435
gene id: 1167006:UWK_RS04435
uniprot id: M1PCI9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

1167006:UWK RS17790
gene id: 1167006:UWK_RS17790
uniprot id: M1NKH9
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1167006:UWK RS08055
gene id: 1167006:UWK_RS08055
uniprot id: M1NEP4
names: Subcellular Location Annotation
messages: Cytoplasm

1167006:UWK RS16140
gene id: 1167006:UWK_RS16140
uniprot id: M1PTV4
names: Function
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

1167006:UWK RS12650
gene id: 1167006:UWK_RS12650
uniprot id: M1P6L2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 family.
messages: Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer and homodimer.

1167006:UWK RS11035
gene id: 1167006:UWK_RS11035
uniprot id: M1PQT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1167006:UWK RS16295
gene id: 1167006:UWK_RS16295
uniprot id: M1PE02
names: Subunit
messages: Heterodimer of a large and a small subunit.

1167006:UWK RS02965
gene id: 1167006:UWK_RS02965
uniprot id: M1NBI3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1167006:UWK RS16395
gene id: 1167006:UWK_RS16395
uniprot id: M1PE22
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS05060
gene id: 1167006:UWK_RS05060
uniprot id: M1P7B5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1167006:UWK RS16835
gene id: 1167006:UWK_RS16835
uniprot id: M1PUA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1167006:UWK RS03980
gene id: 1167006:UWK_RS03980
uniprot id: M1NC50
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1167006:UWK RS08480
gene id: 1167006:UWK_RS08480
uniprot id: M1NEZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1167006:UWK RS01040
gene id: 1167006:UWK_RS01040
uniprot id: M1P503
names: Similarity
messages: Belongs to the P(II) protein family.

1167006:UWK RS01895
gene id: 1167006:UWK_RS01895
uniprot id: M1P0D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell inner membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1167006:UWK RS14715
gene id: 1167006:UWK_RS14715
uniprot id: M1PD20
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

1167006:UWK RS12785
gene id: 1167006:UWK_RS12785
uniprot id: M1PRY4
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1167006:UWK RS05795
gene id: 1167006:UWK_RS05795
uniprot id: M1PDA3
names: Similarity
messages: Belongs to the HypE family.

1167006:UWK RS08005
gene id: 1167006:UWK_RS08005
uniprot id: M1NEN5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1167006:UWK RS10175
gene id: 1167006:UWK_RS10175
uniprot id: M1PFZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1167006:UWK RS00070
gene id: 1167006:UWK_RS00070
uniprot id: M1N9S1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1167006:UWK RS01830
gene id: 1167006:UWK_RS01830
uniprot id: M1PB03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1167006:UWK RS11485
gene id: 1167006:UWK_RS11485
uniprot id: M1PB28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1167006:UWK RS12620
gene id: 1167006:UWK_RS12620
uniprot id: M1PBS6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1167006:UWK RS10310
gene id: 1167006:UWK_RS10310
uniprot id: M1PAE2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1167006:UWK RS08060
gene id: 1167006:UWK_RS08060
uniprot id: M1PEN7
names: Similarity
messages: Belongs to the UPF0235 family.

1167006:UWK RS04870
gene id: 1167006:UWK_RS04870
uniprot id: M1NCS5
names: Function
names: Similarity
messages: Belongs to the ATPase gamma chain family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1167006:UWK RS13890
gene id: 1167006:UWK_RS13890
uniprot id: M1PSM0
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

1167006:UWK RS17090
gene id: 1167006:UWK_RS17090
uniprot id: M1P931
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1167006:UWK RS11130
gene id: 1167006:UWK_RS11130
uniprot id: M1PGK6
names: Similarity
messages: Belongs to the MEMO1 family.

1167006:UWK RS10455
gene id: 1167006:UWK_RS10455
uniprot id: M1PQG9
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

1167006:UWK RS14460
gene id: 1167006:UWK_RS14460
uniprot id: M1NIQ6
names: Similarity
messages: Belongs to the TrpF family.

1167006:UWK RS06205
gene id: 1167006:UWK_RS06205
uniprot id: M1PDK5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1167006:UWK RS04265
gene id: 1167006:UWK_RS04265
uniprot id: M1PCF2
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1167006:UWK RS12795
gene id: 1167006:UWK_RS12795
uniprot id: M1P6N3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

1167006:UWK RS14465
gene id: 1167006:UWK_RS14465
uniprot id: M1PIM9
names: Similarity
messages: Belongs to the TrpC family.

1167006:UWK RS08825
gene id: 1167006:UWK_RS08825
uniprot id: M1P9J9
names: Similarity
messages: Belongs to the glutamine synthetase family.

1167006:UWK RS00250
gene id: 1167006:UWK_RS00250
uniprot id: M1NZF1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1167006:UWK RS16900
gene id: 1167006:UWK_RS16900
uniprot id: M1PK63
names: Similarity
messages: Belongs to the fabD family.

1167006:UWK RS14390
gene id: 1167006:UWK_RS14390
uniprot id: M1PSY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1167006:UWK RS15530
gene id: 1167006:UWK_RS15530
uniprot id: M1P852
names: Similarity
messages: Belongs to the peptidase S1C family.

1167006:UWK RS02620
gene id: 1167006:UWK_RS02620
uniprot id: M1NBC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1167006:UWK RS14075
gene id: 1167006:UWK_RS14075
uniprot id: M1NIH4
names: Similarity
messages: Belongs to the CutA family.

1167006:UWK RS10440
gene id: 1167006:UWK_RS10440
uniprot id: M1NG59
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

1167006:UWK RS06660
gene id: 1167006:UWK_RS06660
uniprot id: M1PDW8
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

1167006:UWK RS04060
gene id: 1167006:UWK_RS04060
uniprot id: M1PCA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1167006:UWK RS02040
gene id: 1167006:UWK_RS02040
uniprot id: M1PB68
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1167006:UWK RS11555
gene id: 1167006:UWK_RS11555
uniprot id: M1PR57
names: Similarity
messages: Belongs to the universal stress protein A family.

1167006:UWK RS09315
gene id: 1167006:UWK_RS09315
uniprot id: M1PFI5
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS14485
gene id: 1167006:UWK_RS14485
uniprot id: M1NIR1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1167006:UWK RS17340
gene id: 1167006:UWK_RS17340
uniprot id: M1PEP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1167006:UWK RS13735
gene id: 1167006:UWK_RS13735
uniprot id: M1P749
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1167006:UWK RS03435
gene id: 1167006:UWK_RS03435
uniprot id: M1P6B7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1167006:UWK RS04510
gene id: 1167006:UWK_RS04510
uniprot id: M1PM10
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1167006:UWK RS03630
gene id: 1167006:UWK_RS03630
uniprot id: M1PLE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1167006:UWK RS10955
gene id: 1167006:UWK_RS10955
uniprot id: M1PGG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1167006:UWK RS03975
gene id: 1167006:UWK_RS03975
uniprot id: M1P1H7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1167006:UWK RS09205
gene id: 1167006:UWK_RS09205
uniprot id: M1P4K2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1167006:UWK RS16090
gene id: 1167006:UWK_RS16090
uniprot id: M1PJN6
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS16890
gene id: 1167006:UWK_RS16890
uniprot id: M1P8Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1167006:UWK RS16495
gene id: 1167006:UWK_RS16495
uniprot id: M1PE39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1167006:UWK RS16625
gene id: 1167006:UWK_RS16625
uniprot id: M1PJZ3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1167006:UWK RS02175
gene id: 1167006:UWK_RS02175
uniprot id: M1PKL4
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1167006:UWK RS05615
gene id: 1167006:UWK_RS05615
uniprot id: M1P2H8
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1167006:UWK RS05810
gene id: 1167006:UWK_RS05810
uniprot id: M1P2L9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

1167006:UWK RS14060
gene id: 1167006:UWK_RS14060
uniprot id: M1PSR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

1167006:UWK RS11935
gene id: 1167006:UWK_RS11935
uniprot id: M1NH56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1167006:UWK RS08445
gene id: 1167006:UWK_RS08445
uniprot id: M1P9B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1167006:UWK RS07995
gene id: 1167006:UWK_RS07995
uniprot id: M1P925
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1167006:UWK RS04375
gene id: 1167006:UWK_RS04375
uniprot id: M1P1S7
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

1167006:UWK RS12415
gene id: 1167006:UWK_RS12415
uniprot id: M1PBP1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1167006:UWK RS03585
gene id: 1167006:UWK_RS03585
uniprot id: M1P6E1
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

1167006:UWK RS10500
gene id: 1167006:UWK_RS10500
uniprot id: M1PG63
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

1167006:UWK RS04890
gene id: 1167006:UWK_RS04890
uniprot id: M1P244
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1167006:UWK RS12505
gene id: 1167006:UWK_RS12505
uniprot id: M1PHH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1167006:UWK RS17585
gene id: 1167006:UWK_RS17585
uniprot id: M1PET7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1167006:UWK RS13600
gene id: 1167006:UWK_RS13600
uniprot id: M1P727
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1167006:UWK RS17265
gene id: 1167006:UWK_RS17265
uniprot id: M1PEM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1167006:UWK RS13035
gene id: 1167006:UWK_RS13035
uniprot id: M1PC07
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1167006:UWK RS10120
gene id: 1167006:UWK_RS10120
uniprot id: M1NFZ5
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1167006:UWK RS05765
gene id: 1167006:UWK_RS05765
uniprot id: M1ND85
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.
messages: Periplasm

1167006:UWK RS17480
gene id: 1167006:UWK_RS17480
uniprot id: M1PUP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1167006:UWK RS00105
gene id: 1167006:UWK_RS00105
uniprot id: M1N9S5
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1167006:UWK RS03785
gene id: 1167006:UWK_RS03785
uniprot id: M1NC06
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS14640
gene id: 1167006:UWK_RS14640
uniprot id: M1PT52
names: Similarity
messages: Belongs to the CobH/CbiC family.

1167006:UWK RS13885
gene id: 1167006:UWK_RS13885
uniprot id: M1PIA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1167006:UWK RS05445
gene id: 1167006:UWK_RS05445
uniprot id: M1P7I8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1167006:UWK RS03790
gene id: 1167006:UWK_RS03790
uniprot id: M1PC50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1167006:UWK RS11925
gene id: 1167006:UWK_RS11925
uniprot id: M1PBD2
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

1167006:UWK RS05310
gene id: 1167006:UWK_RS05310
uniprot id: M1P2C3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

1167006:UWK RS02440
gene id: 1167006:UWK_RS02440
uniprot id: M1P0N3
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1167006:UWK RS07840
gene id: 1167006:UWK_RS07840
uniprot id: M1P901
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1167006:UWK RS00735
gene id: 1167006:UWK_RS00735
uniprot id: M1P4U4
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1167006:UWK RS17455
gene id: 1167006:UWK_RS17455
uniprot id: M1PUN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

1167006:UWK RS09415
gene id: 1167006:UWK_RS09415
uniprot id: M1PFK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1167006:UWK RS08280
gene id: 1167006:UWK_RS08280
uniprot id: M1NEU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1167006:UWK RS09400
gene id: 1167006:UWK_RS09400
uniprot id: M1P9Y4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1167006:UWK RS08970
gene id: 1167006:UWK_RS08970
uniprot id: M1P9N0
names: Similarity
messages: Belongs to the CapA family.

1167006:UWK RS17570
gene id: 1167006:UWK_RS17570
uniprot id: M1NKE6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1167006:UWK RS08230
gene id: 1167006:UWK_RS08230
uniprot id: M1NES8
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

1167006:UWK RS11610
gene id: 1167006:UWK_RS11610
uniprot id: M1P5X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S49 family.
messages: Cell inner membrane

1167006:UWK RS02590
gene id: 1167006:UWK_RS02590
uniprot id: M1PBF8
names: Similarity
messages: Belongs to the hemerythrin family.

1167006:UWK RS09065
gene id: 1167006:UWK_RS09065
uniprot id: M1NFD7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1167006:UWK RS11950
gene id: 1167006:UWK_RS11950
uniprot id: M1PBD9
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS11645
gene id: 1167006:UWK_RS11645
uniprot id: M1NGY7
names: Similarity
messages: Belongs to the thioredoxin family.

1167006:UWK RS08180
gene id: 1167006:UWK_RS08180
uniprot id: M1NER7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1167006:UWK RS08615
gene id: 1167006:UWK_RS08615
uniprot id: M1PPD9
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS07990
gene id: 1167006:UWK_RS07990
uniprot id: M1PP17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1167006:UWK RS13040
gene id: 1167006:UWK_RS13040
uniprot id: M1P6S9
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1167006:UWK RS17215
gene id: 1167006:UWK_RS17215
uniprot id: M1PEL8
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

1167006:UWK RS17640
gene id: 1167006:UWK_RS17640
uniprot id: M1PUR8
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1167006:UWK RS04795
gene id: 1167006:UWK_RS04795
uniprot id: M1PCR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

1167006:UWK RS02900
gene id: 1167006:UWK_RS02900
uniprot id: M1P637
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1167006:UWK RS15385
gene id: 1167006:UWK_RS15385
uniprot id: M1NJ99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1167006:UWK RS02010
gene id: 1167006:UWK_RS02010
uniprot id: M1PKI5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

1167006:UWK RS03430
gene id: 1167006:UWK_RS03430
uniprot id: M1PL96
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1167006:UWK RS12285
gene id: 1167006:UWK_RS12285
uniprot id: M1PHD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1167006:UWK RS00555
gene id: 1167006:UWK_RS00555
uniprot id: M1PJL6
names: Similarity
messages: Belongs to the histone deacetylase family.

1167006:UWK RS15780
gene id: 1167006:UWK_RS15780
uniprot id: M1PDN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1167006:UWK RS15405
gene id: 1167006:UWK_RS15405
uniprot id: M1P831
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

1167006:UWK RS15305
gene id: 1167006:UWK_RS15305
uniprot id: M1P814
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1167006:UWK RS14130
gene id: 1167006:UWK_RS14130
uniprot id: M1PST4
names: Similarity
messages: Belongs to the type II topoisomerase GyrB family.

1167006:UWK RS15295
gene id: 1167006:UWK_RS15295
uniprot id: M1PTF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1167006:UWK RS16105
gene id: 1167006:UWK_RS16105
uniprot id: M1P8G3
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1167006:UWK RS14385
gene id: 1167006:UWK_RS14385
uniprot id: M1PIL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1167006:UWK RS16340
gene id: 1167006:UWK_RS16340
uniprot id: M1PU01
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1167006:UWK RS03960
gene id: 1167006:UWK_RS03960
uniprot id: M1PLL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1167006:UWK RS09010
gene id: 1167006:UWK_RS09010
uniprot id: M1NFC4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

1167006:UWK RS17390
gene id: 1167006:UWK_RS17390
uniprot id: M1PEQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1167006:UWK RS08505
gene id: 1167006:UWK_RS08505
uniprot id: M1NF00
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1167006:UWK RS13925
gene id: 1167006:UWK_RS13925
uniprot id: M1P780
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1167006:UWK RS01655
gene id: 1167006:UWK_RS01655
uniprot id: M1P503
names: Similarity
messages: Belongs to the P(II) protein family.

1167006:UWK RS07300
gene id: 1167006:UWK_RS07300
uniprot id: M1P3J2
names: Similarity
messages: Belongs to the GSP E family.

1167006:UWK RS18515
gene id: 1167006:UWK_RS18515
uniprot id: M1PQ52
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS07355
gene id: 1167006:UWK_RS07355
uniprot id: M1NEC2
names: Similarity
messages: Belongs to the SUI1 family.

1167006:UWK RS16255
gene id: 1167006:UWK_RS16255
uniprot id: M1P8J2
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

1167006:UWK RS16310
gene id: 1167006:UWK_RS16310
uniprot id: M1PJT4
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

1167006:UWK RS14010
gene id: 1167006:UWK_RS14010
uniprot id: M1PSQ3
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1167006:UWK RS08745
gene id: 1167006:UWK_RS08745
uniprot id: M1P9I3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1167006:UWK RS16975
gene id: 1167006:UWK_RS16975
uniprot id: M1PK86
names: Similarity
messages: Belongs to the UPF0251 family.

1167006:UWK RS12160
gene id: 1167006:UWK_RS12160
uniprot id: M1NHB4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1167006:UWK RS02625
gene id: 1167006:UWK_RS02625
uniprot id: M1PBG1
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1167006:UWK RS08780
gene id: 1167006:UWK_RS08780
uniprot id: M1NF68
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1167006:UWK RS01585
gene id: 1167006:UWK_RS01585
uniprot id: M1PK62
names: Similarity
messages: Belongs to the AOR/FOR family.

1167006:UWK RS04110
gene id: 1167006:UWK_RS04110
uniprot id: M1P6Q7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1167006:UWK RS10875
gene id: 1167006:UWK_RS10875
uniprot id: M1NGF0
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS05090
gene id: 1167006:UWK_RS05090
uniprot id: M1P279
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

1167006:UWK RS00495
gene id: 1167006:UWK_RS00495
uniprot id: M1PA55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1167006:UWK RS11340
gene id: 1167006:UWK_RS11340
uniprot id: M1P5P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1167006:UWK RS11080
gene id: 1167006:UWK_RS11080
uniprot id: M1PQU6
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1167006:UWK RS13745
gene id: 1167006:UWK_RS13745
uniprot id: M1PI82
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1167006:UWK RS04560
gene id: 1167006:UWK_RS04560
uniprot id: M1PCN3
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

1167006:UWK RS03275
gene id: 1167006:UWK_RS03275
uniprot id: M1P698
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

1167006:UWK RS10265
gene id: 1167006:UWK_RS10265
uniprot id: M1PAD3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1167006:UWK RS14530
gene id: 1167006:UWK_RS14530
uniprot id: M1PCY0
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

1167006:UWK RS05790
gene id: 1167006:UWK_RS05790
uniprot id: M1ND90
names: Similarity
messages: Belongs to the HypD family.

1167006:UWK RS05415
gene id: 1167006:UWK_RS05415
uniprot id: M1PD16
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1167006:UWK RS08875
gene id: 1167006:UWK_RS08875
uniprot id: M1P4C5
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1167006:UWK RS17145
gene id: 1167006:UWK_RS17145
uniprot id: M1P951
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS04240
gene id: 1167006:UWK_RS04240
uniprot id: M1NCB5
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS00110
gene id: 1167006:UWK_RS00110
uniprot id: M1P9Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1167006:UWK RS11140
gene id: 1167006:UWK_RS11140
uniprot id: M1PAV1
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS03460
gene id: 1167006:UWK_RS03460
uniprot id: M1P6B9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1167006:UWK RS12790
gene id: 1167006:UWK_RS12790
uniprot id: M1PBV7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1167006:UWK RS16960
gene id: 1167006:UWK_RS16960
uniprot id: M1PED6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1167006:UWK RS11675
gene id: 1167006:UWK_RS11675
uniprot id: M1PR88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

1167006:UWK RS02595
gene id: 1167006:UWK_RS02595
uniprot id: M1PKU0
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1167006:UWK RS08655
gene id: 1167006:UWK_RS08655
uniprot id: M1NF39
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1167006:UWK RS05550
gene id: 1167006:UWK_RS05550
uniprot id: M1PD40
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1167006:UWK RS11780
gene id: 1167006:UWK_RS11780
uniprot id: M1PB95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1167006:UWK RS00550
gene id: 1167006:UWK_RS00550
uniprot id: M1PA66
names: Similarity
messages: Belongs to the D-alanine--D-alanine ligase family.

1167006:UWK RS04705
gene id: 1167006:UWK_RS04705
uniprot id: M1PM55
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1167006:UWK RS16515
gene id: 1167006:UWK_RS16515
uniprot id: M1PU37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1167006:UWK RS05390
gene id: 1167006:UWK_RS05390
uniprot id: M1PD14
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1167006:UWK RS10305
gene id: 1167006:UWK_RS10305
uniprot id: M1PQE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1167006:UWK RS03470
gene id: 1167006:UWK_RS03470
uniprot id: M1NBS8
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1167006:UWK RS09090
gene id: 1167006:UWK_RS09090
uniprot id: M1PFC7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1167006:UWK RS11020
gene id: 1167006:UWK_RS11020
uniprot id: M1P5I8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1167006:UWK RS17410
gene id: 1167006:UWK_RS17410
uniprot id: M1PUM8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1167006:UWK RS07975
gene id: 1167006:UWK_RS07975
uniprot id: M1P3V3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1167006:UWK RS01395
gene id: 1167006:UWK_RS01395
uniprot id: M1PAP6
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

1167006:UWK RS01195
gene id: 1167006:UWK_RS01195
uniprot id: M1PJY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

1167006:UWK RS07295
gene id: 1167006:UWK_RS07295
uniprot id: M1P8Q9
names: Similarity
messages: Belongs to the GSP E family.

1167006:UWK RS08485
gene id: 1167006:UWK_RS08485
uniprot id: M1PEY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1167006:UWK RS13910
gene id: 1167006:UWK_RS13910
uniprot id: M1PIB4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1167006:UWK RS17530
gene id: 1167006:UWK_RS17530
uniprot id: M1PUP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1167006:UWK RS06585
gene id: 1167006:UWK_RS06585
uniprot id: M1NDT4
names: Similarity
messages: Belongs to the threonine synthase family.

1167006:UWK RS16985
gene id: 1167006:UWK_RS16985
uniprot id: M1PEE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

1167006:UWK RS10950
gene id: 1167006:UWK_RS10950
uniprot id: M1NGG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1167006:UWK RS06695
gene id: 1167006:UWK_RS06695
uniprot id: M1P363
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1167006:UWK RS10920
gene id: 1167006:UWK_RS10920
uniprot id: M1P5G8
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS01775
gene id: 1167006:UWK_RS01775
uniprot id: M1NAT5
names: Similarity
messages: Belongs to the radical SAM superfamily. NifB family.

1167006:UWK RS15555
gene id: 1167006:UWK_RS15555
uniprot id: M1P857
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

1167006:UWK RS07715
gene id: 1167006:UWK_RS07715
uniprot id: M1P8Y1
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS16575
gene id: 1167006:UWK_RS16575
uniprot id: M1PU49
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1167006:UWK RS06665
gene id: 1167006:UWK_RS06665
uniprot id: M1PN88
names: Subcellular Location Annotation
messages: Periplasm

1167006:UWK RS12125
gene id: 1167006:UWK_RS12125
uniprot id: M1P6D0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1167006:UWK RS07785
gene id: 1167006:UWK_RS07785
uniprot id: M1PNX6
names: Similarity
messages: Belongs to the peptidase M16 family.

1167006:UWK RS13935
gene id: 1167006:UWK_RS13935
uniprot id: M1PIC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1167006:UWK RS13515
gene id: 1167006:UWK_RS13515
uniprot id: M1P714
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

1167006:UWK RS15550
gene id: 1167006:UWK_RS15550
uniprot id: M1PDJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1167006:UWK RS10485
gene id: 1167006:UWK_RS10485
uniprot id: M1PAH5
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS00135
gene id: 1167006:UWK_RS00135
uniprot id: M1P9Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1167006:UWK RS02090
gene id: 1167006:UWK_RS02090
uniprot id: M1PB78
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS07585
gene id: 1167006:UWK_RS07585
uniprot id: M1PEE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

1167006:UWK RS08490
gene id: 1167006:UWK_RS08490
uniprot id: M1PPB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1167006:UWK RS16400
gene id: 1167006:UWK_RS16400
uniprot id: M1P8M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1167006:UWK RS07865
gene id: 1167006:UWK_RS07865
uniprot id: M1P904
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1167006:UWK RS13580
gene id: 1167006:UWK_RS13580
uniprot id: M1NI66
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1167006:UWK RS14560
gene id: 1167006:UWK_RS14560
uniprot id: M1P7M8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1167006:UWK RS13465
gene id: 1167006:UWK_RS13465
uniprot id: M1PCA2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1167006:UWK RS09620
gene id: 1167006:UWK_RS09620
uniprot id: M1PQ39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1167006:UWK RS14780
gene id: 1167006:UWK_RS14780
uniprot id: M1NJ00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1167006:UWK RS01670
gene id: 1167006:UWK_RS01670
uniprot id: M1NAQ8
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1167006:UWK RS10670
gene id: 1167006:UWK_RS10670
uniprot id: M1P5B9
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

1167006:UWK RS09180
gene id: 1167006:UWK_RS09180
uniprot id: M1P4J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1167006:UWK RS07090
gene id: 1167006:UWK_RS07090
uniprot id: M1PE75
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS02055
gene id: 1167006:UWK_RS02055
uniprot id: M1P0H8
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS07000
gene id: 1167006:UWK_RS07000
uniprot id: M1PE42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1167006:UWK RS07605
gene id: 1167006:UWK_RS07605
uniprot id: M1NEF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1167006:UWK RS11725
gene id: 1167006:UWK_RS11725
uniprot id: M1PRA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

1167006:UWK RS01365
gene id: 1167006:UWK_RS01365
uniprot id: M1PAP1
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS11135
gene id: 1167006:UWK_RS11135
uniprot id: M1PQV6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1167006:UWK RS03105
gene id: 1167006:UWK_RS03105
uniprot id: M1P0Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

1167006:UWK RS15420
gene id: 1167006:UWK_RS15420
uniprot id: M1PTH2
names: Subcellular Location Annotation
messages: Secreted

1167006:UWK RS08675
gene id: 1167006:UWK_RS08675
uniprot id: M1P486
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

1167006:UWK RS02930
gene id: 1167006:UWK_RS02930
uniprot id: M1P642
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

1167006:UWK RS07505
gene id: 1167006:UWK_RS07505
uniprot id: M1NEE5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1167006:UWK RS08990
gene id: 1167006:UWK_RS08990
uniprot id: M1PPM9
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS17290
gene id: 1167006:UWK_RS17290
uniprot id: M1PEN3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1167006:UWK RS13215
gene id: 1167006:UWK_RS13215
uniprot id: M1P6W0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell inner membrane
messages: Membrane

1167006:UWK RS04055
gene id: 1167006:UWK_RS04055
uniprot id: M1NC67
names: Similarity
messages: Belongs to the SecB family.

1167006:UWK RS05350
gene id: 1167006:UWK_RS05350
uniprot id: M1P7G9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1167006:UWK RS17415
gene id: 1167006:UWK_RS17415
uniprot id: M1PEQ6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1167006:UWK RS02325
gene id: 1167006:UWK_RS02325
uniprot id: M1PKP1
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1167006:UWK RS18665
gene id: 1167006:UWK_RS18665
uniprot id: M1NIE5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1167006:UWK RS09020
gene id: 1167006:UWK_RS09020
uniprot id: M1PPN7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1167006:UWK RS04635
gene id: 1167006:UWK_RS04635
uniprot id: M1PCP5
names: Similarity
messages: Belongs to the DNA photolyase class-2 family.

1167006:UWK RS03990
gene id: 1167006:UWK_RS03990
uniprot id: M1PLM5
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1167006:UWK RS00540
gene id: 1167006:UWK_RS00540
uniprot id: M1NZJ7
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

1167006:UWK RS04335
gene id: 1167006:UWK_RS04335
uniprot id: M1NCE3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1167006:UWK RS13950
gene id: 1167006:UWK_RS13950
uniprot id: M1P788
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1167006:UWK RS07855
gene id: 1167006:UWK_RS07855
uniprot id: M1PEJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1167006:UWK RS11980
gene id: 1167006:UWK_RS11980
uniprot id: M1P676
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1167006:UWK RS00905
gene id: 1167006:UWK_RS00905
uniprot id: M1PAD5
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1167006:UWK RS11910
gene id: 1167006:UWK_RS11910
uniprot id: M1NH50
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1167006:UWK RS10215
gene id: 1167006:UWK_RS10215
uniprot id: M1P538
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1167006:UWK RS01565
gene id: 1167006:UWK_RS01565
uniprot id: M1P5C2
names: Similarity
messages: Belongs to the hemerythrin family.

1167006:UWK RS08470
gene id: 1167006:UWK_RS08470
uniprot id: M1P9C4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1167006:UWK RS16065
gene id: 1167006:UWK_RS16065
uniprot id: M1PJN1
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1167006:UWK RS06715
gene id: 1167006:UWK_RS06715
uniprot id: M1P8C0
names: Similarity
messages: Belongs to the asparagine synthetase family.

1167006:UWK RS13940
gene id: 1167006:UWK_RS13940
uniprot id: M1PSN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1167006:UWK RS03445
gene id: 1167006:UWK_RS03445
uniprot id: M1NBS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1167006:UWK RS01695
gene id: 1167006:UWK_RS01695
uniprot id: M1P084
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-97 inactivates the nitrogenase reductase and regulates nitrogenase activity.

1167006:UWK RS07165
gene id: 1167006:UWK_RS07165
uniprot id: M1PE87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1167006:UWK RS01190
gene id: 1167006:UWK_RS01190
uniprot id: M1PAK1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

1167006:UWK RS14210
gene id: 1167006:UWK_RS14210
uniprot id: M1PCR1
names: Similarity
messages: Belongs to the MipA/OmpV family.

1167006:UWK RS15065
gene id: 1167006:UWK_RS15065
uniprot id: M1PJ16
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1167006:UWK RS10200
gene id: 1167006:UWK_RS10200
uniprot id: M1PFZ7
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1167006:UWK RS12855
gene id: 1167006:UWK_RS12855
uniprot id: M1PHQ3
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1167006:UWK RS11475
gene id: 1167006:UWK_RS11475
uniprot id: M1PGT9
names: Similarity
messages: Belongs to the RNA polymerase subunit omega family.

1167006:UWK RS10890
gene id: 1167006:UWK_RS10890
uniprot id: M1PAP9
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1167006:UWK RS11615
gene id: 1167006:UWK_RS11615
uniprot id: M1NGY2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1167006:UWK RS17365
gene id: 1167006:UWK_RS17365
uniprot id: M1PEP8
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1167006:UWK RS16235
gene id: 1167006:UWK_RS16235
uniprot id: M1NJP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
messages: Homodimer.
messages: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.

1167006:UWK RS10115
gene id: 1167006:UWK_RS10115
uniprot id: M1P521
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1167006:UWK RS10860
gene id: 1167006:UWK_RS10860
uniprot id: M1PQP5
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1167006:UWK RS10660
gene id: 1167006:UWK_RS10660
uniprot id: M1PQK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1167006:UWK RS05940
gene id: 1167006:UWK_RS05940
uniprot id: M1PDE0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1167006:UWK RS14420
gene id: 1167006:UWK_RS14420
uniprot id: M1PCV7
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS04125
gene id: 1167006:UWK_RS04125
uniprot id: M1PCC1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1167006:UWK RS17945
gene id: 1167006:UWK_RS17945
uniprot id: M1PEZ9
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1167006:UWK RS11490
gene id: 1167006:UWK_RS11490
uniprot id: M1P5T8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

1167006:UWK RS06040
gene id: 1167006:UWK_RS06040
uniprot id: M1PDG8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1167006:UWK RS02050
gene id: 1167006:UWK_RS02050
uniprot id: M1P5Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

1167006:UWK RS10070
gene id: 1167006:UWK_RS10070
uniprot id: M1NFY9
names: Similarity
messages: Belongs to the HdrA family.

1167006:UWK RS01730
gene id: 1167006:UWK_RS01730
uniprot id: M1PAX9
names: Similarity
messages: Belongs to the ArsC family.

1167006:UWK RS15145
gene id: 1167006:UWK_RS15145
uniprot id: M1PJ30
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1167006:UWK RS06825
gene id: 1167006:UWK_RS06825
uniprot id: M1P394
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1167006:UWK RS16100
gene id: 1167006:UWK_RS16100
uniprot id: M1PDV7
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1167006:UWK RS15445
gene id: 1167006:UWK_RS15445
uniprot id: M1PTH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1167006:UWK RS15250
gene id: 1167006:UWK_RS15250
uniprot id: M1PDC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

1167006:UWK RS17650
gene id: 1167006:UWK_RS17650
uniprot id: M1P9E7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1167006:UWK RS03140
gene id: 1167006:UWK_RS03140
uniprot id: M1PBQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1167006:UWK RS08370
gene id: 1167006:UWK_RS08370
uniprot id: M1P9A0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1167006:UWK RS11550
gene id: 1167006:UWK_RS11550
uniprot id: M1PGV7
names: Similarity
messages: Belongs to the peptidase M16 family.

1167006:UWK RS12875
gene id: 1167006:UWK_RS12875
uniprot id: M1NHQ9
names: Similarity
messages: Belongs to the histone deacetylase family.

1167006:UWK RS02485
gene id: 1167006:UWK_RS02485
uniprot id: M1P0P0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1167006:UWK RS01770
gene id: 1167006:UWK_RS01770
uniprot id: M1P0A2
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

1167006:UWK RS06635
gene id: 1167006:UWK_RS06635
uniprot id: M1PDW2
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

1167006:UWK RS14775
gene id: 1167006:UWK_RS14775
uniprot id: M1P7R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1167006:UWK RS17325
gene id: 1167006:UWK_RS17325
uniprot id: M1NKA7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1167006:UWK RS02565
gene id: 1167006:UWK_RS02565
uniprot id: M1PBF4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1167006:UWK RS11885
gene id: 1167006:UWK_RS11885
uniprot id: M1NH44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1167006:UWK RS00790
gene id: 1167006:UWK_RS00790
uniprot id: M1NZN4
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

1167006:UWK RS04000
gene id: 1167006:UWK_RS04000
uniprot id: M1P1I3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1167006:UWK RS08665
gene id: 1167006:UWK_RS08665
uniprot id: M1PPE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1167006:UWK RS16425
gene id: 1167006:UWK_RS16425
uniprot id: M1P8M8
names: Similarity
messages: Belongs to the LOG family.

1167006:UWK RS15730
gene id: 1167006:UWK_RS15730
uniprot id: M1PDM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1167006:UWK RS16840
gene id: 1167006:UWK_RS16840
uniprot id: M1P8X2
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1167006:UWK RS06515
gene id: 1167006:UWK_RS06515
uniprot id: M1PDS9
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

1167006:UWK RS14920
gene id: 1167006:UWK_RS14920
uniprot id: M1PD56
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1167006:UWK RS12730
gene id: 1167006:UWK_RS12730
uniprot id: M1PHM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1167006:UWK RS12565
gene id: 1167006:UWK_RS12565
uniprot id: M1PBR7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1167006:UWK RS10435
gene id: 1167006:UWK_RS10435
uniprot id: M1P574
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

1167006:UWK RS11405
gene id: 1167006:UWK_RS11405
uniprot id: M1PR19
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Heterodimer of a large and a small subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

1167006:UWK RS10015
gene id: 1167006:UWK_RS10015
uniprot id: M1P510
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

1167006:UWK RS11765
gene id: 1167006:UWK_RS11765
uniprot id: M1NH16
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS14270
gene id: 1167006:UWK_RS14270
uniprot id: M1NIL3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1167006:UWK RS05220
gene id: 1167006:UWK_RS05220
uniprot id: M1PCY5
names: Similarity
messages: Belongs to the HdrA family.

1167006:UWK RS18085
gene id: 1167006:UWK_RS18085
uniprot id: M1PKJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RTX toxin acyltransferase family.
messages: Cytoplasm
messages: Involved in fatty acylation of protoxin at internal lysine residues, thereby converting it to the active toxin.

1167006:UWK RS14185
gene id: 1167006:UWK_RS14185
uniprot id: M1PCQ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1167006:UWK RS10290
gene id: 1167006:UWK_RS10290
uniprot id: M1PAD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1167006:UWK RS01290
gene id: 1167006:UWK_RS01290
uniprot id: M1PAM5
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS15075
gene id: 1167006:UWK_RS15075
uniprot id: M1PD90
names: Subunit
messages: Heterodimer of a large and a small subunit.

1167006:UWK RS14415
gene id: 1167006:UWK_RS14415
uniprot id: M1PSZ5
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS11180
gene id: 1167006:UWK_RS11180
uniprot id: M1PGL7
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1167006:UWK RS02305
gene id: 1167006:UWK_RS02305
uniprot id: M1P5T9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

1167006:UWK RS08805
gene id: 1167006:UWK_RS08805
uniprot id: M1NF75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1167006:UWK RS10355
gene id: 1167006:UWK_RS10355
uniprot id: M1PQF2
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1167006:UWK RS17230
gene id: 1167006:UWK_RS17230
uniprot id: M1PKG2
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

1167006:UWK RS08340
gene id: 1167006:UWK_RS08340
uniprot id: M1PP85
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1167006:UWK RS17295
gene id: 1167006:UWK_RS17295
uniprot id: M1P989
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1167006:UWK RS00115
gene id: 1167006:UWK_RS00115
uniprot id: M1PJD9
names: Similarity
messages: Belongs to the threonine synthase family.

1167006:UWK RS07285
gene id: 1167006:UWK_RS07285
uniprot id: M1PEA5
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS18285
gene id: 1167006:UWK_RS18285
uniprot id: M1P2L0
names: Similarity
messages: Belongs to the hemerythrin family.
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1167006:UWK RS08105
gene id: 1167006:UWK_RS08105
uniprot id: M1NEQ1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1167006:UWK RS00360
gene id: 1167006:UWK_RS00360
uniprot id: M1N9X7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1167006:UWK RS08795
gene id: 1167006:UWK_RS08795
uniprot id: M1P9J3
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

1167006:UWK RS17610
gene id: 1167006:UWK_RS17610
uniprot id: M1PUR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1167006:UWK RS08110
gene id: 1167006:UWK_RS08110
uniprot id: M1PEP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1167006:UWK RS13930
gene id: 1167006:UWK_RS13930
uniprot id: M1NIE0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1167006:UWK RS16715
gene id: 1167006:UWK_RS16715
uniprot id: M1P8U3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1167006:UWK RS11585
gene id: 1167006:UWK_RS11585
uniprot id: M1P5W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1167006:UWK RS16640
gene id: 1167006:UWK_RS16640
uniprot id: M1P8S3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1167006:UWK RS13175
gene id: 1167006:UWK_RS13175
uniprot id: M1PHW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1167006:UWK RS07525
gene id: 1167006:UWK_RS07525
uniprot id: M1P3M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1167006:UWK RS16240
gene id: 1167006:UWK_RS16240
uniprot id: M1PJR7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1167006:UWK RS01845
gene id: 1167006:UWK_RS01845
uniprot id: M1P0C2
names: Subcellular Location Annotation
messages: Cytoplasm

1167006:UWK RS10160
gene id: 1167006:UWK_RS10160
uniprot id: M1PAB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1167006:UWK RS16135
gene id: 1167006:UWK_RS16135
uniprot id: M1PJP7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1167006:UWK RS01175
gene id: 1167006:UWK_RS01175
uniprot id: M1P527
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.

1167006:UWK RS15510
gene id: 1167006:UWK_RS15510
uniprot id: M1NJB7
names: Similarity
messages: Belongs to the type III secretion exporter family.

1167006:UWK RS04390
gene id: 1167006:UWK_RS04390
uniprot id: M1PLX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1167006:UWK RS03940
gene id: 1167006:UWK_RS03940
uniprot id: M1P6L9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1167006:UWK RS11720
gene id: 1167006:UWK_RS11720
uniprot id: M1PGZ8
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

1167006:UWK RS00445
gene id: 1167006:UWK_RS00445
uniprot id: M1PA43
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

1167006:UWK RS00330
gene id: 1167006:UWK_RS00330
uniprot id: M1NZG1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1167006:UWK RS04660
gene id: 1167006:UWK_RS04660
uniprot id: M1PM48
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1167006:UWK RS15320
gene id: 1167006:UWK_RS15320
uniprot id: M1PTF5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

1167006:UWK RS15810
gene id: 1167006:UWK_RS15810
uniprot id: M1P8A0
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family.

1167006:UWK RS05235
gene id: 1167006:UWK_RS05235
uniprot id: M1P2A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

1167006:UWK RS14900
gene id: 1167006:UWK_RS14900
uniprot id: M1P7U1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1167006:UWK RS16590
gene id: 1167006:UWK_RS16590
uniprot id: M1NJV5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1167006:UWK RS01925
gene id: 1167006:UWK_RS01925
uniprot id: M1NAX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1167006:UWK RS08545
gene id: 1167006:UWK_RS08545
uniprot id: M1P9D9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1167006:UWK RS01705
gene id: 1167006:UWK_RS01705
uniprot id: M1PAX1
names: Similarity
messages: Belongs to the P(II) protein family.

1167006:UWK RS18340
gene id: 1167006:UWK_RS18340
uniprot id: M1NE36
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS08080
gene id: 1167006:UWK_RS08080
uniprot id: M1NEP7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

1167006:UWK RS14745
gene id: 1167006:UWK_RS14745
uniprot id: M1PD22
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1167006:UWK RS05325
gene id: 1167006:UWK_RS05325
uniprot id: M1P7G4
names: Similarity
messages: Belongs to the autoinducer synthase family.

1167006:UWK RS01615
gene id: 1167006:UWK_RS01615
uniprot id: M1P5D7
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1167006:UWK RS07345
gene id: 1167006:UWK_RS07345
uniprot id: M1P8R7
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1167006:UWK RS00365
gene id: 1167006:UWK_RS00365
uniprot id: M1PA29
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1167006:UWK RS09835
gene id: 1167006:UWK_RS09835
uniprot id: M1PA72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1167006:UWK RS17665
gene id: 1167006:UWK_RS17665
uniprot id: M1PUS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1167006:UWK RS12345
gene id: 1167006:UWK_RS12345
uniprot id: M1PBM7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1167006:UWK RS15390
gene id: 1167006:UWK_RS15390
uniprot id: M1PJ79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: Periplasm
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1167006:UWK RS13550
gene id: 1167006:UWK_RS13550
uniprot id: M1P718
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1167006:UWK RS06180
gene id: 1167006:UWK_RS06180
uniprot id: M1PDJ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

1167006:UWK RS13100
gene id: 1167006:UWK_RS13100
uniprot id: M1PHV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1167006:UWK RS09735
gene id: 1167006:UWK_RS09735
uniprot id: M1NFU3
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS17245
gene id: 1167006:UWK_RS17245
uniprot id: M1P980
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

1167006:UWK RS02585
gene id: 1167006:UWK_RS02585
uniprot id: M1NBB6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

1167006:UWK RS09615
gene id: 1167006:UWK_RS09615
uniprot id: M1PFQ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1167006:UWK RS16420
gene id: 1167006:UWK_RS16420
uniprot id: M1PE28
names: Similarity
messages: Belongs to the GSP E family.

1167006:UWK RS12770
gene id: 1167006:UWK_RS12770
uniprot id: M1P6M9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1167006:UWK RS10990
gene id: 1167006:UWK_RS10990
uniprot id: M1PAR9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1167006:UWK RS14410
gene id: 1167006:UWK_RS14410
uniprot id: M1PIL8
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS10755
gene id: 1167006:UWK_RS10755
uniprot id: M1NGC5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1167006:UWK RS18455
gene id: 1167006:UWK_RS18455
uniprot id: M1NFG8
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1167006:UWK RS12255
gene id: 1167006:UWK_RS12255
uniprot id: M1NHD2
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS05375
gene id: 1167006:UWK_RS05375
uniprot id: M1P7H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1167006:UWK RS00910
gene id: 1167006:UWK_RS00910
uniprot id: M1PJT0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1167006:UWK RS17685
gene id: 1167006:UWK_RS17685
uniprot id: M1PKP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1167006:UWK RS17630
gene id: 1167006:UWK_RS17630
uniprot id: M1NKF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1167006:UWK RS17300
gene id: 1167006:UWK_RS17300
uniprot id: M1NKA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

1167006:UWK RS07370
gene id: 1167006:UWK_RS07370
uniprot id: M1P8S1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

1167006:UWK RS03440
gene id: 1167006:UWK_RS03440
uniprot id: M1P150
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1167006:UWK RS17085
gene id: 1167006:UWK_RS17085
uniprot id: M1PEG5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1167006:UWK RS05805
gene id: 1167006:UWK_RS05805
uniprot id: M1P7Q4
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

1167006:UWK RS06755
gene id: 1167006:UWK_RS06755
uniprot id: M1NDY4
names: Similarity
messages: Belongs to the glycosyl hydrolase 8 (cellulase D) family.

1167006:UWK RS10185
gene id: 1167006:UWK_RS10185
uniprot id: M1PAC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1167006:UWK RS11695
gene id: 1167006:UWK_RS11695
uniprot id: M1PGZ2
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1167006:UWK RS05770
gene id: 1167006:UWK_RS05770
uniprot id: M1PD94
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

1167006:UWK RS00935
gene id: 1167006:UWK_RS00935
uniprot id: M1PJT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

1167006:UWK RS02160
gene id: 1167006:UWK_RS02160
uniprot id: M1P0J4
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1167006:UWK RS17355
gene id: 1167006:UWK_RS17355
uniprot id: M1PKI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1167006:UWK RS16210
gene id: 1167006:UWK_RS16210
uniprot id: M1NJP0
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1167006:UWK RS04200
gene id: 1167006:UWK_RS04200
uniprot id: M1PLS3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

1167006:UWK RS11380
gene id: 1167006:UWK_RS11380
uniprot id: M1PR13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1167006:UWK RS10370
gene id: 1167006:UWK_RS10370
uniprot id: M1NG44
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1167006:UWK RS01170
gene id: 1167006:UWK_RS01170
uniprot id: M1PJX6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1167006:UWK RS09275
gene id: 1167006:UWK_RS09275
uniprot id: M1P9V4
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS14670
gene id: 1167006:UWK_RS14670
uniprot id: M1PD15
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1167006:UWK RS16895
gene id: 1167006:UWK_RS16895
uniprot id: M1NK09
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1167006:UWK RS08065
gene id: 1167006:UWK_RS08065
uniprot id: M1PP30
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.

1167006:UWK RS03185
gene id: 1167006:UWK_RS03185
uniprot id: M1NBM4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1167006:UWK RS00460
gene id: 1167006:UWK_RS00460
uniprot id: M1NZI4
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS00125
gene id: 1167006:UWK_RS00125
uniprot id: M1NZD7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1167006:UWK RS15815
gene id: 1167006:UWK_RS15815
uniprot id: M1NJG8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1167006:UWK RS10050
gene id: 1167006:UWK_RS10050
uniprot id: M1PFX0
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1167006:UWK RS12365
gene id: 1167006:UWK_RS12365
uniprot id: M1PBN3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1167006:UWK RS10760
gene id: 1167006:UWK_RS10760
uniprot id: M1PGC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1167006:UWK RS04675
gene id: 1167006:UWK_RS04675
uniprot id: M1PCQ2
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1167006:UWK RS06845
gene id: 1167006:UWK_RS06845
uniprot id: M1P8F3
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1167006:UWK RS13750
gene id: 1167006:UWK_RS13750
uniprot id: M1PSI9
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1167006:UWK RS12860
gene id: 1167006:UWK_RS12860
uniprot id: M1PRZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1167006:UWK RS08050
gene id: 1167006:UWK_RS08050
uniprot id: M1P3W6
names: Similarity
messages: Belongs to the YggT family.

1167006:UWK RS10315
gene id: 1167006:UWK_RS10315
uniprot id: M1P555
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1167006:UWK RS13965
gene id: 1167006:UWK_RS13965
uniprot id: M1PSP1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1167006:UWK RS16490
gene id: 1167006:UWK_RS16490
uniprot id: M1PU32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1167006:UWK RS01605
gene id: 1167006:UWK_RS01605
uniprot id: M1PAU6
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

1167006:UWK RS14550
gene id: 1167006:UWK_RS14550
uniprot id: M1PT24
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1167006:UWK RS08800
gene id: 1167006:UWK_RS08800
uniprot id: M1P4A9
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1167006:UWK RS18505
gene id: 1167006:UWK_RS18505
uniprot id: M1PQ32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1167006:UWK RS11040
gene id: 1167006:UWK_RS11040
uniprot id: M1PAS9
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1167006:UWK RS07945
gene id: 1167006:UWK_RS07945
uniprot id: M1P917
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1167006:UWK RS04595
gene id: 1167006:UWK_RS04595
uniprot id: M1P735
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

1167006:UWK RS15090
gene id: 1167006:UWK_RS15090
uniprot id: M1PJ21
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1167006:UWK RS04970
gene id: 1167006:UWK_RS04970
uniprot id: M1PCU5
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1167006:UWK RS04990
gene id: 1167006:UWK_RS04990
uniprot id: M1NCU8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1167006:UWK RS05045
gene id: 1167006:UWK_RS05045
uniprot id: M1NCV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1167006:UWK RS08855
gene id: 1167006:UWK_RS08855
uniprot id: M1NF88
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1167006:UWK RS07005
gene id: 1167006:UWK_RS07005
uniprot id: M1PNG8
names: Similarity
messages: Belongs to the AOR/FOR family.

1167006:UWK RS16260
gene id: 1167006:UWK_RS16260
uniprot id: M1NJP8
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS09920
gene id: 1167006:UWK_RS09920
uniprot id: M1NFX0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1167006:UWK RS04780
gene id: 1167006:UWK_RS04780
uniprot id: M1P766
names: Similarity
messages: Belongs to the histone deacetylase family.

1167006:UWK RS00130
gene id: 1167006:UWK_RS00130
uniprot id: M1N9T0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1167006:UWK RS12980
gene id: 1167006:UWK_RS12980
uniprot id: M1PS18
names: Similarity
messages: Belongs to the peptidase S16 family.

1167006:UWK RS05775
gene id: 1167006:UWK_RS05775
uniprot id: M1PMQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

1167006:UWK RS14065
gene id: 1167006:UWK_RS14065
uniprot id: M1PCM7
names: Similarity
messages: Belongs to the peptidase S66 family.

1167006:UWK RS09195
gene id: 1167006:UWK_RS09195
uniprot id: M1PPT7
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1167006:UWK RS06450
gene id: 1167006:UWK_RS06450
uniprot id: M1P854
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1167006:UWK RS09525
gene id: 1167006:UWK_RS09525
uniprot id: M1P4S3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1167006:UWK RS05555
gene id: 1167006:UWK_RS05555
uniprot id: M1PMK6
names: Similarity
messages: Belongs to the UPF0758 family.

1167006:UWK RS08755
gene id: 1167006:UWK_RS08755
uniprot id: M1NF62
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS03945
gene id: 1167006:UWK_RS03945
uniprot id: M1P1H1
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS16830
gene id: 1167006:UWK_RS16830
uniprot id: M1PK43
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1167006:UWK RS08295
gene id: 1167006:UWK_RS08295
uniprot id: M1P982
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1167006:UWK RS00465
gene id: 1167006:UWK_RS00465
uniprot id: M1N9Z8
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS20000
gene id: 1167006:UWK_RS20000
uniprot id: M1PDG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1167006:UWK RS10800
gene id: 1167006:UWK_RS10800
uniprot id: M1P5E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1167006:UWK RS00120
gene id: 1167006:UWK_RS00120
uniprot id: M1P4I9
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

1167006:UWK RS12340
gene id: 1167006:UWK_RS12340
uniprot id: M1PRQ8
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1167006:UWK RS00325
gene id: 1167006:UWK_RS00325
uniprot id: M1P4M6
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1167006:UWK RS04845
gene id: 1167006:UWK_RS04845
uniprot id: M1NCS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsB sub-subfamily.
messages: Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane

1167006:UWK RS04175
gene id: 1167006:UWK_RS04175
uniprot id: M1PLR6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

1167006:UWK RS00160
gene id: 1167006:UWK_RS00160
uniprot id: M1P9Z8
names: Similarity
messages: Belongs to the glutamate synthase family.

1167006:UWK RS10535
gene id: 1167006:UWK_RS10535
uniprot id: M1PQI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1167006:UWK RS16275
gene id: 1167006:UWK_RS16275
uniprot id: M1PDZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1167006:UWK RS04015
gene id: 1167006:UWK_RS04015
uniprot id: M1PLN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1167006:UWK RS02545
gene id: 1167006:UWK_RS02545
uniprot id: M1PKT2
names: Similarity
messages: Belongs to the GSP E family.

1167006:UWK RS06445
gene id: 1167006:UWK_RS06445
uniprot id: M1PN36
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1167006:UWK RS09095
gene id: 1167006:UWK_RS09095
uniprot id: M1PPQ9
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

1167006:UWK RS10255
gene id: 1167006:UWK_RS10255
uniprot id: M1PG05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1167006:UWK RS00620
gene id: 1167006:UWK_RS00620
uniprot id: M1NA27
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1167006:UWK RS05080
gene id: 1167006:UWK_RS05080
uniprot id: M1PMC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

1167006:UWK RS17620
gene id: 1167006:UWK_RS17620
uniprot id: M1PEU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1167006:UWK RS07920
gene id: 1167006:UWK_RS07920
uniprot id: M1PP00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1167006:UWK RS00915
gene id: 1167006:UWK_RS00915
uniprot id: M1P4X9
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

1167006:UWK RS17395
gene id: 1167006:UWK_RS17395
uniprot id: M1P9A5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1167006:UWK RS06510
gene id: 1167006:UWK_RS06510
uniprot id: M1NDR2
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

1167006:UWK RS04070
gene id: 1167006:UWK_RS04070
uniprot id: M1P6P9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1167006:UWK RS00440
gene id: 1167006:UWK_RS00440
uniprot id: M1N9Z4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1167006:UWK RS10170
gene id: 1167006:UWK_RS10170
uniprot id: M1PAB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1167006:UWK RS14290
gene id: 1167006:UWK_RS14290
uniprot id: M1P7H0
names: Similarity
messages: Belongs to the RecJ family.

1167006:UWK RS17450
gene id: 1167006:UWK_RS17450
uniprot id: M1PKK2
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS16405
gene id: 1167006:UWK_RS16405
uniprot id: M1NJS6
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS09840
gene id: 1167006:UWK_RS09840
uniprot id: M1P4Y6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1167006:UWK RS11665
gene id: 1167006:UWK_RS11665
uniprot id: M1P5Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1167006:UWK RS10210
gene id: 1167006:UWK_RS10210
uniprot id: M1PAC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1167006:UWK RS08100
gene id: 1167006:UWK_RS08100
uniprot id: M1P3X7
names: Similarity
messages: Belongs to the DprA/Smf family.

1167006:UWK RS04280
gene id: 1167006:UWK_RS04280
uniprot id: M1P1Q3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1167006:UWK RS01155
gene id: 1167006:UWK_RS01155
uniprot id: M1NZV9
names: Similarity
messages: Belongs to the peptidase C40 family.

1167006:UWK RS06745
gene id: 1167006:UWK_RS06745
uniprot id: M1P8C7
names: Function
names: Subcellular Location Annotation
messages: Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose.
messages: Cell inner membrane

1167006:UWK RS17625
gene id: 1167006:UWK_RS17625
uniprot id: M1P9E3
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1167006:UWK RS07405
gene id: 1167006:UWK_RS07405
uniprot id: M1PEC1
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1167006:UWK RS10565
gene id: 1167006:UWK_RS10565
uniprot id: M1PAI9
names: Similarity
messages: Belongs to the Skp family.

1167006:UWK RS13905
gene id: 1167006:UWK_RS13905
uniprot id: M1NID4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1167006:UWK RS14890
gene id: 1167006:UWK_RS14890
uniprot id: M1PT87
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1167006:UWK RS01005
gene id: 1167006:UWK_RS01005
uniprot id: M1PAF7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1167006:UWK RS13210
gene id: 1167006:UWK_RS13210
uniprot id: M1PC47
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1167006:UWK RS04905
gene id: 1167006:UWK_RS04905
uniprot id: M1PM91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase epsilon chain family.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1167006:UWK RS06320
gene id: 1167006:UWK_RS06320
uniprot id: M1P824
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS05035
gene id: 1167006:UWK_RS05035
uniprot id: M1P7A8
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS10555
gene id: 1167006:UWK_RS10555
uniprot id: M1PG75
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1167006:UWK RS01030
gene id: 1167006:UWK_RS01030
uniprot id: M1PAG4
names: Similarity
messages: Belongs to the glutamate synthase family.

1167006:UWK RS14280
gene id: 1167006:UWK_RS14280
uniprot id: M1PSW8
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1167006:UWK RS10940
gene id: 1167006:UWK_RS10940
uniprot id: M1PAQ8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1167006:UWK RS16905
gene id: 1167006:UWK_RS16905
uniprot id: M1PUC4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1167006:UWK RS18260
gene id: 1167006:UWK_RS18260
uniprot id: M1PMH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1167006:UWK RS08090
gene id: 1167006:UWK_RS08090
uniprot id: M1PP35
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1167006:UWK RS09470
gene id: 1167006:UWK_RS09470
uniprot id: M1PPZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1167006:UWK RS09560
gene id: 1167006:UWK_RS09560
uniprot id: M1NFR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1167006:UWK RS07600
gene id: 1167006:UWK_RS07600
uniprot id: M1P3P3
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

1167006:UWK RS01540
gene id: 1167006:UWK_RS01540
uniprot id: M1P5B6
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 [2Fe-2S] cluster per subunit.

1167006:UWK RS08720
gene id: 1167006:UWK_RS08720
uniprot id: M1P9H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1167006:UWK RS04010
gene id: 1167006:UWK_RS04010
uniprot id: M1PC98
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1167006:UWK RS15035
gene id: 1167006:UWK_RS15035
uniprot id: M1NJ41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1167006:UWK RS13945
gene id: 1167006:UWK_RS13945
uniprot id: M1PCK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1167006:UWK RS05400
gene id: 1167006:UWK_RS05400
uniprot id: M1P7I0
names: Similarity
messages: Belongs to the histone deacetylase family.

1167006:UWK RS07140
gene id: 1167006:UWK_RS07140
uniprot id: M1PE83
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1167006:UWK RS06855
gene id: 1167006:UWK_RS06855
uniprot id: M1NE11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1167006:UWK RS06920
gene id: 1167006:UWK_RS06920
uniprot id: M1PE26
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1167006:UWK RS08270
gene id: 1167006:UWK_RS08270
uniprot id: M1P975
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS17635
gene id: 1167006:UWK_RS17635
uniprot id: M1PKN5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1167006:UWK RS14655
gene id: 1167006:UWK_RS14655
uniprot id: M1NIX6
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

1167006:UWK RS13155
gene id: 1167006:UWK_RS13155
uniprot id: M1PS52
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1167006:UWK RS05650
gene id: 1167006:UWK_RS05650
uniprot id: M1PMM5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1167006:UWK RS18120
gene id: 1167006:UWK_RS18120
uniprot id: M1PL22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1167006:UWK RS05140
gene id: 1167006:UWK_RS05140
uniprot id: M1P291
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

1167006:UWK RS08335
gene id: 1167006:UWK_RS08335
uniprot id: M1PEU9
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS05840
gene id: 1167006:UWK_RS05840
uniprot id: M1PDB3
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1167006:UWK RS08260
gene id: 1167006:UWK_RS08260
uniprot id: M1PET1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1167006:UWK RS01505
gene id: 1167006:UWK_RS01505
uniprot id: M1PK46
names: Similarity
messages: Belongs to the HisA/HisF family.

1167006:UWK RS13895
gene id: 1167006:UWK_RS13895
uniprot id: M1PCJ0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1167006:UWK RS11985
gene id: 1167006:UWK_RS11985
uniprot id: M1NH65
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1167006:UWK RS13065
gene id: 1167006:UWK_RS13065
uniprot id: M1P6T2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1167006:UWK RS11580
gene id: 1167006:UWK_RS11580
uniprot id: M1PB49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1167006:UWK RS06295
gene id: 1167006:UWK_RS06295
uniprot id: M1P818
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1167006:UWK RS13810
gene id: 1167006:UWK_RS13810
uniprot id: M1PCH4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1167006:UWK RS07725
gene id: 1167006:UWK_RS07725
uniprot id: M1NEI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1167006:UWK RS13740
gene id: 1167006:UWK_RS13740
uniprot id: M1NI99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1167006:UWK RS05820
gene id: 1167006:UWK_RS05820
uniprot id: M1PMR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

1167006:UWK RS01595
gene id: 1167006:UWK_RS01595
uniprot id: M1P059
names: Similarity
messages: Belongs to the IlvD/Edd family.

1167006:UWK RS10415
gene id: 1167006:UWK_RS10415
uniprot id: M1NG54
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS05380
gene id: 1167006:UWK_RS05380
uniprot id: M1P2D8
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1167006:UWK RS14070
gene id: 1167006:UWK_RS14070
uniprot id: M1P7B7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1167006:UWK RS12725
gene id: 1167006:UWK_RS12725
uniprot id: M1NHM8
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1167006:UWK RS12715
gene id: 1167006:UWK_RS12715
uniprot id: M1PBU5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1167006:UWK RS12740
gene id: 1167006:UWK_RS12740
uniprot id: M1PBU9
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1167006:UWK RS14320
gene id: 1167006:UWK_RS14320
uniprot id: M1P7H7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1167006:UWK RS09640
gene id: 1167006:UWK_RS09640
uniprot id: M1PQ44
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1167006:UWK RS10585
gene id: 1167006:UWK_RS10585
uniprot id: M1PQJ4
names: Similarity
messages: Belongs to the RemA family.

1167006:UWK RS05180
gene id: 1167006:UWK_RS05180
uniprot id: M1P2A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1167006:UWK RS08255
gene id: 1167006:UWK_RS08255
uniprot id: M1NET5
names: Similarity
messages: Belongs to the thioredoxin family.

1167006:UWK RS16525
gene id: 1167006:UWK_RS16525
uniprot id: M1P8P7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1167006:UWK RS08740
gene id: 1167006:UWK_RS08740
uniprot id: M1PPG2
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1167006:UWK RS10335
gene id: 1167006:UWK_RS10335
uniprot id: M1PAE7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1167006:UWK RS14540
gene id: 1167006:UWK_RS14540
uniprot id: M1NIS7
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

1167006:UWK RS02945
gene id: 1167006:UWK_RS02945
uniprot id: M1PBL6
names: Similarity
messages: Belongs to the citrate synthase family.

1167006:UWK RS11470
gene id: 1167006:UWK_RS11470
uniprot id: M1NGU6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1167006:UWK RS15020
gene id: 1167006:UWK_RS15020
uniprot id: M1PTA5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1167006:UWK RS08520
gene id: 1167006:UWK_RS08520
uniprot id: M1P9D4
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1167006:UWK RS04800
gene id: 1167006:UWK_RS04800
uniprot id: M1PM75
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1167006:UWK RS16690
gene id: 1167006:UWK_RS16690
uniprot id: M1P8T5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1167006:UWK RS10235
gene id: 1167006:UWK_RS10235
uniprot id: M1PAC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1167006:UWK RS07080
gene id: 1167006:UWK_RS07080
uniprot id: M1P3G0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1167006:UWK RS14600
gene id: 1167006:UWK_RS14600
uniprot id: M1PT40
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1167006:UWK RS15775
gene id: 1167006:UWK_RS15775
uniprot id: M1PTM8
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1167006:UWK RS06850
gene id: 1167006:UWK_RS06850
uniprot id: M1P399
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1167006:UWK RS08915
gene id: 1167006:UWK_RS08915
uniprot id: M1PPL0
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1167006:UWK RS03970
gene id: 1167006:UWK_RS03970
uniprot id: M1P6M6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1167006:UWK RS01995
gene id: 1167006:UWK_RS01995
uniprot id: M1P0G8
names: Similarity
messages: Belongs to the leucine-binding protein family.

1167006:UWK RS01185
gene id: 1167006:UWK_RS01185
uniprot id: M1NAD5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

1167006:UWK RS00400
gene id: 1167006:UWK_RS00400
uniprot id: M1PJJ0
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS09050
gene id: 1167006:UWK_RS09050
uniprot id: M1P9P9
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1167006:UWK RS08140
gene id: 1167006:UWK_RS08140
uniprot id: M1PP46
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1167006:UWK RS09880
gene id: 1167006:UWK_RS09880
uniprot id: M1PQ80
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1167006:UWK RS09565
gene id: 1167006:UWK_RS09565
uniprot id: M1PFP7
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1167006:UWK RS02280
gene id: 1167006:UWK_RS02280
uniprot id: M1P5T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

1167006:UWK RS19610
gene id: 1167006:UWK_RS19610
uniprot id: M1PH51
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1167006:UWK RS15255
gene id: 1167006:UWK_RS15255
uniprot id: M1P803
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

1167006:UWK RS16570
gene id: 1167006:UWK_RS16570
uniprot id: M1PJY1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1167006:UWK RS05930
gene id: 1167006:UWK_RS05930
uniprot id: M1P2P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1167006:UWK RS14040
gene id: 1167006:UWK_RS14040
uniprot id: M1PCM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1167006:UWK RS15240
gene id: 1167006:UWK_RS15240
uniprot id: M1PJ48
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1167006:UWK RS06670
gene id: 1167006:UWK_RS06670
uniprot id: M1P8A7
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

1167006:UWK RS18010
gene id: 1167006:UWK_RS18010
uniprot id: M1NA73
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1167006:UWK RS02990
gene id: 1167006:UWK_RS02990
uniprot id: M1NBI8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1167006:UWK RS15665
gene id: 1167006:UWK_RS15665
uniprot id: M1NJE1
names: Similarity
messages: Belongs to the HdrA family.

1167006:UWK RS08980
gene id: 1167006:UWK_RS08980
uniprot id: M1NFB9
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS12055
gene id: 1167006:UWK_RS12055
uniprot id: M1P696
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1167006:UWK RS16385
gene id: 1167006:UWK_RS16385
uniprot id: M1PJU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1167006:UWK RS03075
gene id: 1167006:UWK_RS03075
uniprot id: M1P667
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

1167006:UWK RS10155
gene id: 1167006:UWK_RS10155
uniprot id: M1PQB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1167006:UWK RS02805
gene id: 1167006:UWK_RS02805
uniprot id: M1P0T7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1167006:UWK RS01235
gene id: 1167006:UWK_RS01235
uniprot id: M1NAE6
names: Similarity
messages: Belongs to the peptidase S41A family.

1167006:UWK RS05285
gene id: 1167006:UWK_RS05285
uniprot id: M1P2B7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1167006:UWK RS01460
gene id: 1167006:UWK_RS01460
uniprot id: M1P596
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

1167006:UWK RS12745
gene id: 1167006:UWK_RS12745
uniprot id: M1P6M7
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1167006:UWK RS06275
gene id: 1167006:UWK_RS06275
uniprot id: M1P2V7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1167006:UWK RS04685
gene id: 1167006:UWK_RS04685
uniprot id: M1P752
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS12460
gene id: 1167006:UWK_RS12460
uniprot id: M1PRS6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1167006:UWK RS12755
gene id: 1167006:UWK_RS12755
uniprot id: M1PHN3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1167006:UWK RS17475
gene id: 1167006:UWK_RS17475
uniprot id: M1PKK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

1167006:UWK RS07385
gene id: 1167006:UWK_RS07385
uniprot id: M1PNR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1167006:UWK RS05185
gene id: 1167006:UWK_RS05185
uniprot id: M1NCY2
names: Similarity
messages: Belongs to the Fur family.

1167006:UWK RS14815
gene id: 1167006:UWK_RS14815
uniprot id: M1PT76
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS05465
gene id: 1167006:UWK_RS05465
uniprot id: M1PMJ4
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

1167006:UWK RS14330
gene id: 1167006:UWK_RS14330
uniprot id: M1PIJ9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1167006:UWK RS05860
gene id: 1167006:UWK_RS05860
uniprot id: M1NDA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

1167006:UWK RS19575
gene id: 1167006:UWK_RS19575
uniprot id: M1P7N9
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1167006:UWK RS12615
gene id: 1167006:UWK_RS12615
uniprot id: M1PRV0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1167006:UWK RS04410
gene id: 1167006:UWK_RS04410
uniprot id: M1PCI3
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1167006:UWK RS06170
gene id: 1167006:UWK_RS06170
uniprot id: M1P2T8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1167006:UWK RS10590
gene id: 1167006:UWK_RS10590
uniprot id: M1PAJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1167006:UWK RS08650
gene id: 1167006:UWK_RS08650
uniprot id: M1P482
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1167006:UWK RS01610
gene id: 1167006:UWK_RS01610
uniprot id: M1PK67
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1167006:UWK RS02785
gene id: 1167006:UWK_RS02785
uniprot id: M1NBF0
names: Similarity
messages: Belongs to the glycosyltransferase 1 family.

1167006:UWK RS11455
gene id: 1167006:UWK_RS11455
uniprot id: M1PR32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1167006:UWK RS12625
gene id: 1167006:UWK_RS12625
uniprot id: M1P6K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1167006:UWK RS06250
gene id: 1167006:UWK_RS06250
uniprot id: M1P2V3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1167006:UWK RS07530
gene id: 1167006:UWK_RS07530
uniprot id: M1NEE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1167006:UWK RS09545
gene id: 1167006:UWK_RS09545
uniprot id: M1PA19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1167006:UWK RS15285
gene id: 1167006:UWK_RS15285
uniprot id: M1NJ81
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1167006:UWK RS08705
gene id: 1167006:UWK_RS08705
uniprot id: M1NF50
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1167006:UWK RS09000
gene id: 1167006:UWK_RS09000
uniprot id: M1P9N6
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS04045
gene id: 1167006:UWK_RS04045
uniprot id: M1P6P2
names: Similarity
messages: Belongs to the bacterial secretin family.

1167006:UWK RS01550
gene id: 1167006:UWK_RS01550
uniprot id: M1NAM4
names: Similarity
messages: Belongs to the pyruvate kinase family.

1167006:UWK RS07235
gene id: 1167006:UWK_RS07235
uniprot id: M1PNN3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1167006:UWK RS07315
gene id: 1167006:UWK_RS07315
uniprot id: M1PNP7
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS02810
gene id: 1167006:UWK_RS02810
uniprot id: M1NBF3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

1167006:UWK RS11480
gene id: 1167006:UWK_RS11480
uniprot id: M1PR38
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1167006:UWK RS11895
gene id: 1167006:UWK_RS11895
uniprot id: M1PH41
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS06685
gene id: 1167006:UWK_RS06685
uniprot id: M1PDX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1167006:UWK RS04625
gene id: 1167006:UWK_RS04625
uniprot id: M1P202
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin thioredoxin reductase beta subunit family.
messages: Catalytic subunit of the ferredoxin-thioredoxin reductase (FTR), which catalyzes the two-electron reduction of thioredoxins by the electrons provided by reduced ferredoxin.
messages: Heterodimer of subunit A (variable subunit) and subunit B (catalytic subunit). Heterodimeric FTR forms a complex with ferredoxin and thioredoxin.

1167006:UWK RS06060
gene id: 1167006:UWK_RS06060
uniprot id: M1NDE6
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS11680
gene id: 1167006:UWK_RS11680
uniprot id: M1PB71
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS15745
gene id: 1167006:UWK_RS15745
uniprot id: M1PJF5
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1167006:UWK RS00055
gene id: 1167006:UWK_RS00055
uniprot id: M1PJD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1167006:UWK RS16620
gene id: 1167006:UWK_RS16620
uniprot id: M1NJW0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1167006:UWK RS01295
gene id: 1167006:UWK_RS01295
uniprot id: M1PK04
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS16925
gene id: 1167006:UWK_RS16925
uniprot id: M1PK70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

1167006:UWK RS11510
gene id: 1167006:UWK_RS11510
uniprot id: M1PB34
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1167006:UWK RS10230
gene id: 1167006:UWK_RS10230
uniprot id: M1PQC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1167006:UWK RS10055
gene id: 1167006:UWK_RS10055
uniprot id: M1PQA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

1167006:UWK RS03415
gene id: 1167006:UWK_RS03415
uniprot id: M1P145
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1167006:UWK RS10270
gene id: 1167006:UWK_RS10270
uniprot id: M1P547
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1167006:UWK RS10650
gene id: 1167006:UWK_RS10650
uniprot id: M1NGA3
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1167006:UWK RS01795
gene id: 1167006:UWK_RS01795
uniprot id: M1P0A8
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS15580
gene id: 1167006:UWK_RS15580
uniprot id: M1P861
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1167006:UWK RS15450
gene id: 1167006:UWK_RS15450
uniprot id: M1PDH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1167006:UWK RS01950
gene id: 1167006:UWK_RS01950
uniprot id: M1NAY9
names: Similarity
messages: Belongs to the CinA family.

1167006:UWK RS00200
gene id: 1167006:UWK_RS00200
uniprot id: M1NZE5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1167006:UWK RS18060
gene id: 1167006:UWK_RS18060
uniprot id: M1PKD2
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1167006:UWK RS08555
gene id: 1167006:UWK_RS08555
uniprot id: M1PF01
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1167006:UWK RS08820
gene id: 1167006:UWK_RS08820
uniprot id: M1PPI1
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

1167006:UWK RS01645
gene id: 1167006:UWK_RS01645
uniprot id: M1NAQ2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

1167006:UWK RS17575
gene id: 1167006:UWK_RS17575
uniprot id: M1PKM5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1167006:UWK RS04835
gene id: 1167006:UWK_RS04835
uniprot id: M1P774
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS14245
gene id: 1167006:UWK_RS14245
uniprot id: M1NIK8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1167006:UWK RS17320
gene id: 1167006:UWK_RS17320
uniprot id: M1P993
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1167006:UWK RS13460
gene id: 1167006:UWK_RS13460
uniprot id: M1PSB8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1167006:UWK RS10830
gene id: 1167006:UWK_RS10830
uniprot id: M1NGD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

1167006:UWK RS11870
gene id: 1167006:UWK_RS11870
uniprot id: M1PRE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1167006:UWK RS12965
gene id: 1167006:UWK_RS12965
uniprot id: M1P6R5
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS05505
gene id: 1167006:UWK_RS05505
uniprot id: M1P2F9
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

1167006:UWK RS12350
gene id: 1167006:UWK_RS12350
uniprot id: M1NHE9
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1167006:UWK RS04680
gene id: 1167006:UWK_RS04680
uniprot id: M1PM52
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

1167006:UWK RS07790
gene id: 1167006:UWK_RS07790
uniprot id: M1P8Z4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1167006:UWK RS15705
gene id: 1167006:UWK_RS15705
uniprot id: M1PDM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1167006:UWK RS00470
gene id: 1167006:UWK_RS00470
uniprot id: M1PA48
names: Similarity
messages: Belongs to the leucine-binding protein family.

1167006:UWK RS12385
gene id: 1167006:UWK_RS12385
uniprot id: M1PRR6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1167006:UWK RS15515
gene id: 1167006:UWK_RS15515
uniprot id: M1PJA6
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS02560
gene id: 1167006:UWK_RS02560
uniprot id: M1NBB1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.

1167006:UWK RS12665
gene id: 1167006:UWK_RS12665
uniprot id: M1PRW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1167006:UWK RS11495
gene id: 1167006:UWK_RS11495
uniprot id: M1NGV1
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1167006:UWK RS13620
gene id: 1167006:UWK_RS13620
uniprot id: M1PCD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1167006:UWK RS13015
gene id: 1167006:UWK_RS13015
uniprot id: M1P6S4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1167006:UWK RS14665
gene id: 1167006:UWK_RS14665
uniprot id: M1PT56
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1167006:UWK RS00730
gene id: 1167006:UWK_RS00730
uniprot id: M1PJP8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1167006:UWK RS10880
gene id: 1167006:UWK_RS10880
uniprot id: M1PGF2
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1167006:UWK RS16165
gene id: 1167006:UWK_RS16165
uniprot id: M1PJQ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

1167006:UWK RS00185
gene id: 1167006:UWK_RS00185
uniprot id: M1PA01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1167006:UWK RS12405
gene id: 1167006:UWK_RS12405
uniprot id: M1PHF9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1167006:UWK RS05665
gene id: 1167006:UWK_RS05665
uniprot id: M1ND67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1167006:UWK RS14985
gene id: 1167006:UWK_RS14985
uniprot id: M1NJ32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1167006:UWK RS12835
gene id: 1167006:UWK_RS12835
uniprot id: M1PRZ2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1167006:UWK RS10295
gene id: 1167006:UWK_RS10295
uniprot id: M1NG29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1167006:UWK RS10885
gene id: 1167006:UWK_RS10885
uniprot id: M1PQQ1
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS14255
gene id: 1167006:UWK_RS14255
uniprot id: M1PSW2
names: Subunit
messages: Homotetramer.

1167006:UWK RS03295
gene id: 1167006:UWK_RS03295
uniprot id: M1PL70
names: Function
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.

1167006:UWK RS09580
gene id: 1167006:UWK_RS09580
uniprot id: M1P4U9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1167006:UWK RS11050
gene id: 1167006:UWK_RS11050
uniprot id: M1NGJ2
names: Subcellular Location Annotation
messages: Cytoplasm

1167006:UWK RS13865
gene id: 1167006:UWK_RS13865
uniprot id: M1PCI5
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1167006:UWK RS01470
gene id: 1167006:UWK_RS01470
uniprot id: M1NAK5
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

1167006:UWK RS08690
gene id: 1167006:UWK_RS08690
uniprot id: M1PPF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1167006:UWK RS13280
gene id: 1167006:UWK_RS13280
uniprot id: M1PHY9
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS09980
gene id: 1167006:UWK_RS09980
uniprot id: M1PQ93
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

1167006:UWK RS02215
gene id: 1167006:UWK_RS02215
uniprot id: M1NB47
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1167006:UWK RS04880
gene id: 1167006:UWK_RS04880
uniprot id: M1PM86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1167006:UWK RS03465
gene id: 1167006:UWK_RS03465
uniprot id: M1P155
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1167006:UWK RS12060
gene id: 1167006:UWK_RS12060
uniprot id: M1NH91
names: Similarity
messages: Belongs to the TPP enzyme family.

1167006:UWK RS09390
gene id: 1167006:UWK_RS09390
uniprot id: M1PFK2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1167006:UWK RS16585
gene id: 1167006:UWK_RS16585
uniprot id: M1P8R0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1167006:UWK RS12825
gene id: 1167006:UWK_RS12825
uniprot id: M1NHP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1167006:UWK RS12710
gene id: 1167006:UWK_RS12710
uniprot id: M1PRX0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1167006:UWK RS12610
gene id: 1167006:UWK_RS12610
uniprot id: M1PHK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1167006:UWK RS10180
gene id: 1167006:UWK_RS10180
uniprot id: M1PQC0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1167006:UWK RS08045
gene id: 1167006:UWK_RS08045
uniprot id: M1P935
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1167006:UWK RS10205
gene id: 1167006:UWK_RS10205
uniprot id: M1PQC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1167006:UWK RS05460
gene id: 1167006:UWK_RS05460
uniprot id: M1PD23
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1167006:UWK RS13785
gene id: 1167006:UWK_RS13785
uniprot id: M1PSJ6
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1167006:UWK RS15380
gene id: 1167006:UWK_RS15380
uniprot id: M1P827
names: Subcellular Location Annotation
messages: Periplasm

1167006:UWK RS17335
gene id: 1167006:UWK_RS17335
uniprot id: M1PUL5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1167006:UWK RS05070
gene id: 1167006:UWK_RS05070
uniprot id: M1NCW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1167006:UWK RS16055
gene id: 1167006:UWK_RS16055
uniprot id: M1P8F2
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1167006:UWK RS01760
gene id: 1167006:UWK_RS01760
uniprot id: M1PKA6
names: Similarity
messages: Belongs to the universal stress protein A family.

1167006:UWK RS03405
gene id: 1167006:UWK_RS03405
uniprot id: M1PL89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1167006:UWK RS09645
gene id: 1167006:UWK_RS09645
uniprot id: M1PA45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1167006:UWK RS01975
gene id: 1167006:UWK_RS01975
uniprot id: M1P0F5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1167006:UWK RS08870
gene id: 1167006:UWK_RS08870
uniprot id: M1P9K9
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

1167006:UWK RS10240
gene id: 1167006:UWK_RS10240
uniprot id: M1P543
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1167006:UWK RS15640
gene id: 1167006:UWK_RS15640
uniprot id: M1PJD5
names: Similarity
messages: Belongs to the peptidase M18 family.

1167006:UWK RS11255
gene id: 1167006:UWK_RS11255
uniprot id: M1PQY3
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS05755
gene id: 1167006:UWK_RS05755
uniprot id: M1P7P5
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1167006:UWK RS18250
gene id: 1167006:UWK_RS18250
uniprot id: M1P7A4
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS09510
gene id: 1167006:UWK_RS09510
uniprot id: M1PFM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1167006:UWK RS13555
gene id: 1167006:UWK_RS13555
uniprot id: M1NI61
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1167006:UWK RS09135
gene id: 1167006:UWK_RS09135
uniprot id: M1NFF5
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1167006:UWK RS05410
gene id: 1167006:UWK_RS05410
uniprot id: M1ND20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

1167006:UWK RS14165
gene id: 1167006:UWK_RS14165
uniprot id: M1P7E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1167006:UWK RS17010
gene id: 1167006:UWK_RS17010
uniprot id: M1PEE7
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1167006:UWK RS05890
gene id: 1167006:UWK_RS05890
uniprot id: M1PDC7
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1167006:UWK RS09025
gene id: 1167006:UWK_RS09025
uniprot id: M1P9P2
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS06225
gene id: 1167006:UWK_RS06225
uniprot id: M1P2U8
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1167006:UWK RS05360
gene id: 1167006:UWK_RS05360
uniprot id: M1ND10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1167006:UWK RS10125
gene id: 1167006:UWK_RS10125
uniprot id: M1PFY2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1167006:UWK RS09235
gene id: 1167006:UWK_RS09235
uniprot id: M1NFI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1167006:UWK RS18000
gene id: 1167006:UWK_RS18000
uniprot id: M1P4T7
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS12775
gene id: 1167006:UWK_RS12775
uniprot id: M1NHN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1167006:UWK RS09230
gene id: 1167006:UWK_RS09230
uniprot id: M1P4K7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1167006:UWK RS02150
gene id: 1167006:UWK_RS02150
uniprot id: M1PKL1
names: Similarity
messages: Belongs to the universal stress protein A family.

1167006:UWK RS17030
gene id: 1167006:UWK_RS17030
uniprot id: M1PUF2
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1167006:UWK RS14790
gene id: 1167006:UWK_RS14790
uniprot id: M1PT72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1167006:UWK RS11410
gene id: 1167006:UWK_RS11410
uniprot id: M1PB12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapD family.
messages: Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

1167006:UWK RS16120
gene id: 1167006:UWK_RS16120
uniprot id: M1PDW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1167006:UWK RS15850
gene id: 1167006:UWK_RS15850
uniprot id: M1PTP0
names: Similarity
messages: Belongs to the FBPase class 2 family.

1167006:UWK RS16520
gene id: 1167006:UWK_RS16520
uniprot id: M1PE43
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1167006:UWK RS02975
gene id: 1167006:UWK_RS02975
uniprot id: M1PL09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1167006:UWK RS12540
gene id: 1167006:UWK_RS12540
uniprot id: M1PBR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1167006:UWK RS16290
gene id: 1167006:UWK_RS16290
uniprot id: M1PTY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1167006:UWK RS11875
gene id: 1167006:UWK_RS11875
uniprot id: M1PBB9
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1167006:UWK RS07895
gene id: 1167006:UWK_RS07895
uniprot id: M1P909
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1167006:UWK RS03875
gene id: 1167006:UWK_RS03875
uniprot id: M1PC68
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1167006:UWK RS00340
gene id: 1167006:UWK_RS00340
uniprot id: M1PA25
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1167006:UWK RS17710
gene id: 1167006:UWK_RS17710
uniprot id: M1PKQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1167006:UWK RS08455
gene id: 1167006:UWK_RS08455
uniprot id: M1NEY5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1167006:UWK RS16050
gene id: 1167006:UWK_RS16050
uniprot id: M1PDU7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1167006:UWK RS08250
gene id: 1167006:UWK_RS08250
uniprot id: M1P406
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1167006:UWK RS16030
gene id: 1167006:UWK_RS16030
uniprot id: M1P8E8
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1167006:UWK RS04415
gene id: 1167006:UWK_RS04415
uniprot id: M1PLX5
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS08460
gene id: 1167006:UWK_RS08460
uniprot id: M1PEY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1167006:UWK RS17285
gene id: 1167006:UWK_RS17285
uniprot id: M1PUK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1167006:UWK RS15370
gene id: 1167006:UWK_RS15370
uniprot id: M1PTG4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of five rings (E,L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1167006:UWK RS02015
gene id: 1167006:UWK_RS02015
uniprot id: M1P5P7
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

1167006:UWK RS07065
gene id: 1167006:UWK_RS07065
uniprot id: M1PE70
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1167006:UWK RS04865
gene id: 1167006:UWK_RS04865
uniprot id: M1P241
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS03985
gene id: 1167006:UWK_RS03985
uniprot id: M1PC93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

1167006:UWK RS18410
gene id: 1167006:UWK_RS18410
uniprot id: M1P944
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1167006:UWK RS13695
gene id: 1167006:UWK_RS13695
uniprot id: M1PCF1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1167006:UWK RS12370
gene id: 1167006:UWK_RS12370
uniprot id: M1P6G7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1167006:UWK RS18320
gene id: 1167006:UWK_RS18320
uniprot id: M1PNC7
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS07120
gene id: 1167006:UWK_RS07120
uniprot id: M1PE79
names: Similarity
messages: Belongs to the universal stress protein A family.

1167006:UWK RS05440
gene id: 1167006:UWK_RS05440
uniprot id: M1PMI9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1167006:UWK RS00090
gene id: 1167006:UWK_RS00090
uniprot id: M1P4I5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1167006:UWK RS16130
gene id: 1167006:UWK_RS16130
uniprot id: M1NJM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

1167006:UWK RS14310
gene id: 1167006:UWK_RS14310
uniprot id: M1PCT5
names: Similarity
messages: Belongs to the aspartokinase family.

1167006:UWK RS06830
gene id: 1167006:UWK_RS06830
uniprot id: M1NE04
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1167006:UWK RS04470
gene id: 1167006:UWK_RS04470
uniprot id: M1P1V2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1167006:UWK RS16885
gene id: 1167006:UWK_RS16885
uniprot id: M1PEC3
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1167006:UWK RS04500
gene id: 1167006:UWK_RS04500
uniprot id: M1NCK0
names: Similarity
messages: Belongs to the oxoprolinase family.

1167006:UWK RS05085
gene id: 1167006:UWK_RS05085
uniprot id: M1P7B9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1167006:UWK RS00045
gene id: 1167006:UWK_RS00045
uniprot id: M1N9R6
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1167006:UWK RS14305
gene id: 1167006:UWK_RS14305
uniprot id: M1PSX3
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

1167006:UWK RS02295
gene id: 1167006:UWK_RS02295
uniprot id: M1PBB1
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1167006:UWK RS04495
gene id: 1167006:UWK_RS04495
uniprot id: M1P1V9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1167006:UWK RS00215
gene id: 1167006:UWK_RS00215
uniprot id: M1PJF6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1167006:UWK RS03625
gene id: 1167006:UWK_RS03625
uniprot id: M1PC09
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1167006:UWK RS00480
gene id: 1167006:UWK_RS00480
uniprot id: M1P4Q3
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

1167006:UWK RS08540
gene id: 1167006:UWK_RS08540
uniprot id: M1PPC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1167006:UWK RS10190
gene id: 1167006:UWK_RS10190
uniprot id: M1P534
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1167006:UWK RS13220
gene id: 1167006:UWK_RS13220
uniprot id: M1NHY3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1167006:UWK RS15300
gene id: 1167006:UWK_RS15300
uniprot id: M1PDD8
names: Similarity
messages: Belongs to the MotB family.

1167006:UWK RS09305
gene id: 1167006:UWK_RS09305
uniprot id: M1P4M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1167006:UWK RS16650
gene id: 1167006:UWK_RS16650
uniprot id: M1PK00
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1167006:UWK RS11350
gene id: 1167006:UWK_RS11350
uniprot id: M1PGR0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1167006:UWK RS16580
gene id: 1167006:UWK_RS16580
uniprot id: M1PE53
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1167006:UWK RS04160
gene id: 1167006:UWK_RS04160
uniprot id: M1P1L9
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1167006:UWK RS08695
gene id: 1167006:UWK_RS08695
uniprot id: M1P9H2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1167006:UWK RS10560
gene id: 1167006:UWK_RS10560
uniprot id: M1PQI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1167006:UWK RS08375
gene id: 1167006:UWK_RS08375
uniprot id: M1P431
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

1167006:UWK RS04190
gene id: 1167006:UWK_RS04190
uniprot id: M1NCA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1167006:UWK RS17515
gene id: 1167006:UWK_RS17515
uniprot id: M1P9C5
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

1167006:UWK RS02310
gene id: 1167006:UWK_RS02310
uniprot id: M1P0L6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1167006:UWK RS06235
gene id: 1167006:UWK_RS06235
uniprot id: M1PDL0
names: Caution
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Belongs to the IspF family.
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1167006:UWK RS03215
gene id: 1167006:UWK_RS03215
uniprot id: M1PBS1
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1167006:UWK RS14235
gene id: 1167006:UWK_RS14235
uniprot id: M1PCR7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1167006:UWK RS13780
gene id: 1167006:UWK_RS13780
uniprot id: M1PI87
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.

1167006:UWK RS14090
gene id: 1167006:UWK_RS14090
uniprot id: M1PCN2
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS17645
gene id: 1167006:UWK_RS17645
uniprot id: M1PEU7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1167006:UWK RS06575
gene id: 1167006:UWK_RS06575
uniprot id: M1P881
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS16635
gene id: 1167006:UWK_RS16635
uniprot id: M1PE63
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1167006:UWK RS11205
gene id: 1167006:UWK_RS11205
uniprot id: M1PGM5
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1167006:UWK RS12840
gene id: 1167006:UWK_RS12840
uniprot id: M1PBW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1167006:UWK RS13160
gene id: 1167006:UWK_RS13160
uniprot id: M1PC35
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1167006:UWK RS14405
gene id: 1167006:UWK_RS14405
uniprot id: M1NIP1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1167006:UWK RS15570
gene id: 1167006:UWK_RS15570
uniprot id: M1PTJ3
names: Similarity
messages: Belongs to the DEAD box helicase family.

1167006:UWK RS17035
gene id: 1167006:UWK_RS17035
uniprot id: M1PEF3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1167006:UWK RS10040
gene id: 1167006:UWK_RS10040
uniprot id: M1P514
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1167006:UWK RS05345
gene id: 1167006:UWK_RS05345
uniprot id: M1PMH0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1167006:UWK RS08385
gene id: 1167006:UWK_RS08385
uniprot id: M1PEW1
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1167006:UWK RS01780
gene id: 1167006:UWK_RS01780
uniprot id: M1PAZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell inner membrane
messages: Probably functions as a manganese efflux pump.

1167006:UWK RS14925
gene id: 1167006:UWK_RS14925
uniprot id: M1P7U6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1167006:UWK RS16970
gene id: 1167006:UWK_RS16970
uniprot id: M1NK24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1167006:UWK RS16920
gene id: 1167006:UWK_RS16920
uniprot id: M1NK14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

1167006:UWK RS00295
gene id: 1167006:UWK_RS00295
uniprot id: M1P4M2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1167006:UWK RS08290
gene id: 1167006:UWK_RS08290
uniprot id: M1PP75
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

1167006:UWK RS10540
gene id: 1167006:UWK_RS10540
uniprot id: M1PAI4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

1167006:UWK RS03475
gene id: 1167006:UWK_RS03475
uniprot id: M1PBX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1167006:UWK RS11905
gene id: 1167006:UWK_RS11905
uniprot id: M1PBC6
names: Function
names: Similarity
messages: Belongs to the DtxR/MntR family.
messages: In the presence of manganese, represses expression of mntH and mntS. Up-regulates expression of mntP.

1167006:UWK RS06495
gene id: 1167006:UWK_RS06495
uniprot id: M1PN45
names: Similarity
messages: Belongs to the RutC family.

1167006:UWK RS13720
gene id: 1167006:UWK_RS13720
uniprot id: M1PSI2
names: Similarity
messages: Belongs to the PhoH family.

1167006:UWK RS16345
gene id: 1167006:UWK_RS16345
uniprot id: M1PE13
names: Similarity
messages: Belongs to the peptidase S16 family.

1167006:UWK RS15265
gene id: 1167006:UWK_RS15265
uniprot id: M1PJ53
names: Subcellular Location Annotation
messages: Cytoplasm

1167006:UWK RS08785
gene id: 1167006:UWK_RS08785
uniprot id: M1PF54
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1167006:UWK RS10340
gene id: 1167006:UWK_RS10340
uniprot id: M1P559
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1167006:UWK RS01285
gene id: 1167006:UWK_RS01285
uniprot id: M1NAG0
names: Similarity
messages: Belongs to the GSP E family.

1167006:UWK RS08275
gene id: 1167006:UWK_RS08275
uniprot id: M1P412
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1167006:UWK RS14570
gene id: 1167006:UWK_RS14570
uniprot id: M1PIQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1167006:UWK RS14935
gene id: 1167006:UWK_RS14935
uniprot id: M1PIZ4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1167006:UWK RS17195
gene id: 1167006:UWK_RS17195
uniprot id: M1P972
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS08580
gene id: 1167006:UWK_RS08580
uniprot id: M1NF19
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS00695
gene id: 1167006:UWK_RS00695
uniprot id: M1NA43
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1167006:UWK RS06505
gene id: 1167006:UWK_RS06505
uniprot id: M1P315
names: Similarity
messages: Belongs to the carbamate kinase family.

1167006:UWK RS17065
gene id: 1167006:UWK_RS17065
uniprot id: M1P923
names: Similarity
messages: Belongs to the YkuD family.

1167006:UWK RS00335
gene id: 1167006:UWK_RS00335
uniprot id: M1N9X2
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1167006:UWK RS12970
gene id: 1167006:UWK_RS12970
uniprot id: M1NHT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

1167006:UWK RS15560
gene id: 1167006:UWK_RS15560
uniprot id: M1NJC4
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.

1167006:UWK RS10300
gene id: 1167006:UWK_RS10300
uniprot id: M1PG15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1167006:UWK RS08790
gene id: 1167006:UWK_RS08790
uniprot id: M1PPH6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1167006:UWK RS06240
gene id: 1167006:UWK_RS06240
uniprot id: M1PMZ5
names: Similarity
messages: Belongs to the peptidase M42 family.

1167006:UWK RS01515
gene id: 1167006:UWK_RS01515
uniprot id: M1P041
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1167006:UWK RS11860
gene id: 1167006:UWK_RS11860
uniprot id: M1NH39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1167006:UWK RS02940
gene id: 1167006:UWK_RS02940
uniprot id: M1NBH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine.
messages: Cytoplasm
messages: Homodimer.

1167006:UWK RS00810
gene id: 1167006:UWK_RS00810
uniprot id: M1P4V8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

1167006:UWK RS03235
gene id: 1167006:UWK_RS03235
uniprot id: M1NBN3
names: Similarity
messages: Belongs to the GppA/Ppx family.

1167006:UWK RS03455
gene id: 1167006:UWK_RS03455
uniprot id: M1PLA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1167006:UWK RS16510
gene id: 1167006:UWK_RS16510
uniprot id: M1PJW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1167006:UWK RS03685
gene id: 1167006:UWK_RS03685
uniprot id: M1NBX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1167006:UWK RS04150
gene id: 1167006:UWK_RS04150
uniprot id: M1PLQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

1167006:UWK RS17040
gene id: 1167006:UWK_RS17040
uniprot id: M1P915
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1167006:UWK RS00320
gene id: 1167006:UWK_RS00320
uniprot id: M1PJH7
names: Similarity
messages: Belongs to the UPF0246 family.

1167006:UWK RS07575
gene id: 1167006:UWK_RS07575
uniprot id: M1P3N8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1167006:UWK RS08355
gene id: 1167006:UWK_RS08355
uniprot id: M1NEV9
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS14800
gene id: 1167006:UWK_RS14800
uniprot id: M1P7S3
names: Similarity
messages: Belongs to the TlyA family.

1167006:UWK RS10135
gene id: 1167006:UWK_RS10135
uniprot id: M1PAB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1167006:UWK RS12335
gene id: 1167006:UWK_RS12335
uniprot id: M1PHE7
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS12720
gene id: 1167006:UWK_RS12720
uniprot id: M1P6M2
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1167006:UWK RS13260
gene id: 1167006:UWK_RS13260
uniprot id: M1PS73
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

1167006:UWK RS17115
gene id: 1167006:UWK_RS17115
uniprot id: M1PEH2
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

1167006:UWK RS01225
gene id: 1167006:UWK_RS01225
uniprot id: M1P539
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS12400
gene id: 1167006:UWK_RS12400
uniprot id: M1NHF9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1167006:UWK RS10145
gene id: 1167006:UWK_RS10145
uniprot id: M1NFZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1167006:UWK RS06370
gene id: 1167006:UWK_RS06370
uniprot id: M1P2Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

1167006:UWK RS00385
gene id: 1167006:UWK_RS00385
uniprot id: M1NZH2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1167006:UWK RS15205
gene id: 1167006:UWK_RS15205
uniprot id: M1P7Z5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1167006:UWK RS06955
gene id: 1167006:UWK_RS06955
uniprot id: M1P8H9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1167006:UWK RS06775
gene id: 1167006:UWK_RS06775
uniprot id: M1P381
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1167006:UWK RS10375
gene id: 1167006:UWK_RS10375
uniprot id: M1PG32
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1167006:UWK RS03780
gene id: 1167006:UWK_RS03780
uniprot id: M1P1D5
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS12735
gene id: 1167006:UWK_RS12735
uniprot id: M1PRX6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1167006:UWK RS15945
gene id: 1167006:UWK_RS15945
uniprot id: M1PJK1
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1167006:UWK RS11975
gene id: 1167006:UWK_RS11975
uniprot id: M1PBE5
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1167006:UWK RS15245
gene id: 1167006:UWK_RS15245
uniprot id: M1PTE3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1167006:UWK RS15310
gene id: 1167006:UWK_RS15310
uniprot id: M1NJ86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1167006:UWK RS09460
gene id: 1167006:UWK_RS09460
uniprot id: M1NFM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1167006:UWK RS11685
gene id: 1167006:UWK_RS11685
uniprot id: M1P5Z8
names: Subcellular Location Annotation
messages: Periplasm

1167006:UWK RS04250
gene id: 1167006:UWK_RS04250
uniprot id: M1PLT6
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS04910
gene id: 1167006:UWK_RS04910
uniprot id: M1P784
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1167006:UWK RS04465
gene id: 1167006:UWK_RS04465
uniprot id: M1P6Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

1167006:UWK RS05435
gene id: 1167006:UWK_RS05435
uniprot id: M1PD19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1167006:UWK RS12470
gene id: 1167006:UWK_RS12470
uniprot id: M1P6I6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1167006:UWK RS02460
gene id: 1167006:UWK_RS02460
uniprot id: M1P5W4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1167006:UWK RS06750
gene id: 1167006:UWK_RS06750
uniprot id: M1P375
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AcsB/BcsB family.
messages: Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP).
messages: Cell inner membrane
messages: Tightly associated with the cellulose synthase catalytic subunit.

1167006:UWK RS08515
gene id: 1167006:UWK_RS08515
uniprot id: M1PPB8
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1167006:UWK RS15290
gene id: 1167006:UWK_RS15290
uniprot id: M1PJ58
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1167006:UWK RS03220
gene id: 1167006:UWK_RS03220
uniprot id: M1PL57
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.

1167006:UWK RS12270
gene id: 1167006:UWK_RS12270
uniprot id: M1PBL7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1167006:UWK RS01350
gene id: 1167006:UWK_RS01350
uniprot id: M1P568
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1167006:UWK RS04885
gene id: 1167006:UWK_RS04885
uniprot id: M1P779
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1167006:UWK RS01630
gene id: 1167006:UWK_RS01630
uniprot id: M1PK74
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1167006:UWK RS12455
gene id: 1167006:UWK_RS12455
uniprot id: M1PHG9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1167006:UWK RS03810
gene id: 1167006:UWK_RS03810
uniprot id: M1NC12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1167006:UWK RS07085
gene id: 1167006:UWK_RS07085
uniprot id: M1NE78
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1167006:UWK RS12480
gene id: 1167006:UWK_RS12480
uniprot id: M1PHH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1167006:UWK RS06640
gene id: 1167006:UWK_RS06640
uniprot id: M1PN81
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS08710
gene id: 1167006:UWK_RS08710
uniprot id: M1PF35
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1167006:UWK RS04005
gene id: 1167006:UWK_RS04005
uniprot id: M1NC57
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1167006:UWK RS10915
gene id: 1167006:UWK_RS10915
uniprot id: M1PAQ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.
messages: Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.

1167006:UWK RS11520
gene id: 1167006:UWK_RS11520
uniprot id: M1NGV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1167006:UWK RS06770
gene id: 1167006:UWK_RS06770
uniprot id: M1P8D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1167006:UWK RS10330
gene id: 1167006:UWK_RS10330
uniprot id: M1PQE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1167006:UWK RS10790
gene id: 1167006:UWK_RS10790
uniprot id: M1PQN0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1167006:UWK RS03860
gene id: 1167006:UWK_RS03860
uniprot id: M1P1F4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

1167006:UWK RS15170
gene id: 1167006:UWK_RS15170
uniprot id: M1PTD2
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1167006:UWK RS10130
gene id: 1167006:UWK_RS10130
uniprot id: M1PQB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1167006:UWK RS10345
gene id: 1167006:UWK_RS10345
uniprot id: M1NG38
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1167006:UWK RS16540
gene id: 1167006:UWK_RS16540
uniprot id: M1PJX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1167006:UWK RS07490
gene id: 1167006:UWK_RS07490
uniprot id: M1PNS7
names: Similarity
messages: Belongs to the PhoH family.

1167006:UWK RS07830
gene id: 1167006:UWK_RS07830
uniprot id: M1PEI5
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1167006:UWK RS12670
gene id: 1167006:UWK_RS12670
uniprot id: M1PBT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane

1167006:UWK RS05695
gene id: 1167006:UWK_RS05695
uniprot id: M1PD76
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

1167006:UWK RS09605
gene id: 1167006:UWK_RS09605
uniprot id: M1P4V3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1167006:UWK RS15375
gene id: 1167006:UWK_RS15375
uniprot id: M1PDF6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1167006:UWK RS17525
gene id: 1167006:UWK_RS17525
uniprot id: M1PKL5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1167006:UWK RS00545
gene id: 1167006:UWK_RS00545
uniprot id: M1NA13
names: Similarity
messages: Belongs to the D-alanine--D-alanine ligase family.

1167006:UWK RS14930
gene id: 1167006:UWK_RS14930
uniprot id: M1NJ25
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1167006:UWK RS15180
gene id: 1167006:UWK_RS15180
uniprot id: M1P7Z0
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

1167006:UWK RS17000
gene id: 1167006:UWK_RS17000
uniprot id: M1PK94
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1167006:UWK RS11705
gene id: 1167006:UWK_RS11705
uniprot id: M1PB77
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.

1167006:UWK RS08015
gene id: 1167006:UWK_RS08015
uniprot id: M1PP22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1167006:UWK RS16365
gene id: 1167006:UWK_RS16365
uniprot id: M1PU06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1167006:UWK RS17050
gene id: 1167006:UWK_RS17050
uniprot id: M1PKA7
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

1167006:UWK RS09220
gene id: 1167006:UWK_RS09220
uniprot id: M1PPU2
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1167006:UWK RS01465
gene id: 1167006:UWK_RS01465
uniprot id: M1P025
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1167006:UWK RS08815
gene id: 1167006:UWK_RS08815
uniprot id: M1PF59
names: Similarity
messages: Belongs to the P(II) protein family.

1167006:UWK RS05385
gene id: 1167006:UWK_RS05385
uniprot id: M1ND14
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1167006:UWK RS06030
gene id: 1167006:UWK_RS06030
uniprot id: M1P2R4
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

1167006:UWK RS11690
gene id: 1167006:UWK_RS11690
uniprot id: M1NGZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1167006:UWK RS11090
gene id: 1167006:UWK_RS11090
uniprot id: M1NGK3
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

1167006:UWK RS14505
gene id: 1167006:UWK_RS14505
uniprot id: M1PCX5
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

1167006:UWK RS01680
gene id: 1167006:UWK_RS01680
uniprot id: M1PAW5
names: Function
names: Subunit
messages: Interacts with sigma-54.
messages: Required for activation of most nif operons, which are directly involved in nitrogen fixation.

1167006:UWK RS10220
gene id: 1167006:UWK_RS10220
uniprot id: M1NG13
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1167006:UWK RS06735
gene id: 1167006:UWK_RS06735
uniprot id: M1PDY6
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1167006:UWK RS10325
gene id: 1167006:UWK_RS10325
uniprot id: M1PG21
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1167006:UWK RS15135
gene id: 1167006:UWK_RS15135
uniprot id: M1P7Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1167006:UWK RS09125
gene id: 1167006:UWK_RS09125
uniprot id: M1P9R7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1167006:UWK RS15430
gene id: 1167006:UWK_RS15430
uniprot id: M1P835
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

1167006:UWK RS12890
gene id: 1167006:UWK_RS12890
uniprot id: M1PBX5
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1167006:UWK RS06525
gene id: 1167006:UWK_RS06525
uniprot id: M1P871
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

1167006:UWK RS17280
gene id: 1167006:UWK_RS17280
uniprot id: M1PKH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1167006:UWK RS10380
gene id: 1167006:UWK_RS10380
uniprot id: M1PQF6
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1167006:UWK RS06540
gene id: 1167006:UWK_RS06540
uniprot id: M1PDT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1167006:UWK RS02240
gene id: 1167006:UWK_RS02240
uniprot id: M1NB52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
messages: Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
messages: Homotetramer.

1167006:UWK RS13985
gene id: 1167006:UWK_RS13985
uniprot id: M1PIC8
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS10250
gene id: 1167006:UWK_RS10250
uniprot id: M1NG19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1167006:UWK RS17345
gene id: 1167006:UWK_RS17345
uniprot id: M1P998
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1167006:UWK RS16745
gene id: 1167006:UWK_RS16745
uniprot id: M1P8U7
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS04235
gene id: 1167006:UWK_RS04235
uniprot id: M1P1N9
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS12275
gene id: 1167006:UWK_RS12275
uniprot id: M1P6F0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1167006:UWK RS16965
gene id: 1167006:UWK_RS16965
uniprot id: M1P900
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1167006:UWK RS15525
gene id: 1167006:UWK_RS15525
uniprot id: M1PDI6
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS04825
gene id: 1167006:UWK_RS04825
uniprot id: M1PCS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1167006:UWK RS15335
gene id: 1167006:UWK_RS15335
uniprot id: M1NJ91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1167006:UWK RS03555
gene id: 1167006:UWK_RS03555
uniprot id: M1PLC9
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS16910
gene id: 1167006:UWK_RS16910
uniprot id: M1PEC6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1167006:UWK RS14340
gene id: 1167006:UWK_RS14340
uniprot id: M1PCU2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

1167006:UWK RS15750
gene id: 1167006:UWK_RS15750
uniprot id: M1PTM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1167006:UWK RS01560
gene id: 1167006:UWK_RS01560
uniprot id: M1PK57
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1167006:UWK RS15315
gene id: 1167006:UWK_RS15315
uniprot id: M1PJ64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

1167006:UWK RS08245
gene id: 1167006:UWK_RS08245
uniprot id: M1P971
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1167006:UWK RS06035
gene id: 1167006:UWK_RS06035
uniprot id: M1NDE0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1167006:UWK RS01710
gene id: 1167006:UWK_RS01710
uniprot id: M1PK92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

1167006:UWK RS12705
gene id: 1167006:UWK_RS12705
uniprot id: M1PHM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1167006:UWK RS15330
gene id: 1167006:UWK_RS15330
uniprot id: M1P817
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1167006:UWK RS15940
gene id: 1167006:UWK_RS15940
uniprot id: M1NJI8
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1167006:UWK RS05900
gene id: 1167006:UWK_RS05900
uniprot id: M1P7S7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1167006:UWK RS13075
gene id: 1167006:UWK_RS13075
uniprot id: M1PHU8
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

1167006:UWK RS05515
gene id: 1167006:UWK_RS05515
uniprot id: M1PD33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1167006:UWK RS01415
gene id: 1167006:UWK_RS01415
uniprot id: M1P015
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

1167006:UWK RS18125
gene id: 1167006:UWK_RS18125
uniprot id: M1PL61
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1167006:UWK RS01455
gene id: 1167006:UWK_RS01455
uniprot id: M1PK35
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1167006:UWK RS07470
gene id: 1167006:UWK_RS07470
uniprot id: M1P8T8
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

1167006:UWK RS15235
gene id: 1167006:UWK_RS15235
uniprot id: M1NJ73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1167006:UWK RS02575
gene id: 1167006:UWK_RS02575
uniprot id: M1P5Y4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1167006:UWK RS14025
gene id: 1167006:UWK_RS14025
uniprot id: M1NIG3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1167006:UWK RS03190
gene id: 1167006:UWK_RS03190
uniprot id: M1PBR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

1167006:UWK RS06260
gene id: 1167006:UWK_RS06260
uniprot id: M1PDL8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1167006:UWK RS15175
gene id: 1167006:UWK_RS15175
uniprot id: M1PDB2
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

1167006:UWK RS09625
gene id: 1167006:UWK_RS09625
uniprot id: M1PA41
names: Similarity
messages: Belongs to the citrate synthase family.

1167006:UWK RS05540
gene id: 1167006:UWK_RS05540
uniprot id: M1P2G3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

1167006:UWK RS15885
gene id: 1167006:UWK_RS15885
uniprot id: M1P8B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1167006:UWK RS01625
gene id: 1167006:UWK_RS01625
uniprot id: M1NAP6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1167006:UWK RS18170
gene id: 1167006:UWK_RS18170
uniprot id: M1PC57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1167006:UWK RS15340
gene id: 1167006:UWK_RS15340
uniprot id: M1PJ69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1167006:UWK RS10420
gene id: 1167006:UWK_RS10420
uniprot id: M1PG46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell inner membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1167006:UWK RS07455
gene id: 1167006:UWK_RS07455
uniprot id: M1NED6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the desulfoferrodoxin family.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.
messages: Homodimer.

1167006:UWK RS14525
gene id: 1167006:UWK_RS14525
uniprot id: M1PT18
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1167006:UWK RS02315
gene id: 1167006:UWK_RS02315
uniprot id: M1NB64
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1167006:UWK RS14455
gene id: 1167006:UWK_RS14455
uniprot id: M1P7K6
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1167006:UWK RS13375
gene id: 1167006:UWK_RS13375
uniprot id: M1NI19
names: Similarity
messages: Belongs to the VgrG protein family.

1167006:UWK RS10395
gene id: 1167006:UWK_RS10395
uniprot id: M1NG49
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1167006:UWK RS06790
gene id: 1167006:UWK_RS06790
uniprot id: M1PNC0
names: Similarity
messages: Belongs to the group II decarboxylase family.

1167006:UWK RS17505
gene id: 1167006:UWK_RS17505
uniprot id: M1PUP5
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

1167006:UWK RS00795
gene id: 1167006:UWK_RS00795
uniprot id: M1NA64
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

1167006:UWK RS16230
gene id: 1167006:UWK_RS16230
uniprot id: M1P8I7
names: Similarity
messages: Belongs to the peptidase M1 family.

1167006:UWK RS17690
gene id: 1167006:UWK_RS17690
uniprot id: M1PUS5
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS17375
gene id: 1167006:UWK_RS17375
uniprot id: M1NKB5
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1167006:UWK RS11785
gene id: 1167006:UWK_RS11785
uniprot id: M1P625
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1167006:UWK RS15150
gene id: 1167006:UWK_RS15150
uniprot id: M1PTC7
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1167006:UWK RS14295
gene id: 1167006:UWK_RS14295
uniprot id: M1NIL9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1167006:UWK RS08530
gene id: 1167006:UWK_RS08530
uniprot id: M1NF06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane

1167006:UWK RS09540
gene id: 1167006:UWK_RS09540
uniprot id: M1PQ21
names: Similarity
messages: Belongs to the TPP enzyme family.

1167006:UWK RS11840
gene id: 1167006:UWK_RS11840
uniprot id: M1NH33
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS08145
gene id: 1167006:UWK_RS08145
uniprot id: M1P954
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1167006:UWK RS10195
gene id: 1167006:UWK_RS10195
uniprot id: M1NG08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1167006:UWK RS07730
gene id: 1167006:UWK_RS07730
uniprot id: M1PEG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1167006:UWK RS10165
gene id: 1167006:UWK_RS10165
uniprot id: M1P529
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1167006:UWK RS10360
gene id: 1167006:UWK_RS10360
uniprot id: M1PAF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1167006:UWK RS08955
gene id: 1167006:UWK_RS08955
uniprot id: M1NFB0
names: Similarity
messages: Belongs to the asparagine synthetase family.

1167006:UWK RS17680
gene id: 1167006:UWK_RS17680
uniprot id: M1NKG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1167006:UWK RS15805
gene id: 1167006:UWK_RS15805
uniprot id: M1PDP4
names: Subcellular Location Annotation
messages: Cytoplasm

1167006:UWK RS09100
gene id: 1167006:UWK_RS09100
uniprot id: M1P9R0
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1167006:UWK RS05780
gene id: 1167006:UWK_RS05780
uniprot id: M1P7Q0
names: Function
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.

1167006:UWK RS00925
gene id: 1167006:UWK_RS00925
uniprot id: M1NA87
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

1167006:UWK RS16085
gene id: 1167006:UWK_RS16085
uniprot id: M1NJL6
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS11710
gene id: 1167006:UWK_RS11710
uniprot id: M1P606
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.
messages: Homodimer.

1167006:UWK RS12395
gene id: 1167006:UWK_RS12395
uniprot id: M1P6H2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1167006:UWK RS00725
gene id: 1167006:UWK_RS00725
uniprot id: M1PA98
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1167006:UWK RS17200
gene id: 1167006:UWK_RS17200
uniprot id: M1NK89
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS04475
gene id: 1167006:UWK_RS04475
uniprot id: M1NCI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1167006:UWK RS00060
gene id: 1167006:UWK_RS00060
uniprot id: M1P4I1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1167006:UWK RS06175
gene id: 1167006:UWK_RS06175
uniprot id: M1NDH0
names: Similarity
messages: Belongs to the GSP E family.

1167006:UWK RS08475
gene id: 1167006:UWK_RS08475
uniprot id: M1P451
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1167006:UWK RS00190
gene id: 1167006:UWK_RS00190
uniprot id: M1PJF3
names: Similarity
messages: Belongs to the UPF0111 family.

1167006:UWK RS11145
gene id: 1167006:UWK_RS11145
uniprot id: M1P5L2
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.

1167006:UWK RS00530
gene id: 1167006:UWK_RS00530
uniprot id: M1PJL1
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1167006:UWK RS15910
gene id: 1167006:UWK_RS15910
uniprot id: M1P8C2
names: Subcellular Location Annotation
messages: Membrane

1167006:UWK RS16870
gene id: 1167006:UWK_RS16870
uniprot id: M1NK04
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1167006:UWK RS13285
gene id: 1167006:UWK_RS13285
uniprot id: M1PS77
names: Similarity
messages: Belongs to the FeoA family.

1167006:UWK RS14880
gene id: 1167006:UWK_RS14880
uniprot id: M1NJ17
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Belongs to the GARS family.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1167006:UWK RS15415
gene id: 1167006:UWK_RS15415
uniprot id: M1PJ87
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted