1163617:SCD RS15215
gene id: 1163617:SCD_RS15215
uniprot id: S6AE17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1163617:SCD RS02095
gene id: 1163617:SCD_RS02095
uniprot id: S6AEP9
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1163617:SCD RS04540
gene id: 1163617:SCD_RS04540
uniprot id: S6AJP7
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS14955
gene id: 1163617:SCD_RS14955
uniprot id: S6ABK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1163617:SCD RS04590
gene id: 1163617:SCD_RS04590
uniprot id: S6AJQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1163617:SCD RS06765
gene id: 1163617:SCD_RS06765
uniprot id: S6AA39
names: Similarity
messages: Belongs to the SCO1/2 family.

1163617:SCD RS00900
gene id: 1163617:SCD_RS00900
uniprot id: S6AE70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1163617:SCD RS07585
gene id: 1163617:SCD_RS07585
uniprot id: S6AL46
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1163617:SCD RS14095
gene id: 1163617:SCD_RS14095
uniprot id: S6AP25
names: Function
names: Similarity
messages: Belongs to the RuBisCO large chain family. Type II subfamily.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.

1163617:SCD RS01725
gene id: 1163617:SCD_RS01725
uniprot id: S6AB06
names: Subcellular Location Annotation
messages: Periplasm

1163617:SCD RS06350
gene id: 1163617:SCD_RS06350
uniprot id: S6AKH9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1163617:SCD RS06310
gene id: 1163617:SCD_RS06310
uniprot id: S6AGG0
names: Similarity
messages: Belongs to the MoaD family.

1163617:SCD RS05410
gene id: 1163617:SCD_RS05410
uniprot id: S6AK16
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1163617:SCD RS14050
gene id: 1163617:SCD_RS14050
uniprot id: S6ABB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1163617:SCD RS00790
gene id: 1163617:SCD_RS00790
uniprot id: S6AHL1
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1163617:SCD RS05085
gene id: 1163617:SCD_RS05085
uniprot id: S6AFY8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163617:SCD RS00130
gene id: 1163617:SCD_RS00130
uniprot id: S6AHC1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1163617:SCD RS05615
gene id: 1163617:SCD_RS05615
uniprot id: S6ABS5
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS15160
gene id: 1163617:SCD_RS15160
uniprot id: S6B957
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

1163617:SCD RS01885
gene id: 1163617:SCD_RS01885
uniprot id: S6AI92
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapB family.
messages: Binds 2 heme C groups per subunit.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Electron transfer subunit of the periplasmic nitrate reductase complex NapAB.
messages: Periplasm

1163617:SCD RS15320
gene id: 1163617:SCD_RS15320
uniprot id: S6APM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1163617:SCD RS09720
gene id: 1163617:SCD_RS09720
uniprot id: S6AAF6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Involved in the heme biosynthesis. Catalyzes the anaerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen III to yield the vinyl groups in protoporphyrinogen IX.
messages: Monomer.

1163617:SCD RS09395
gene id: 1163617:SCD_RS09395
uniprot id: S6AAE3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1163617:SCD RS08130
gene id: 1163617:SCD_RS08130
uniprot id: S6ACC5
names: Similarity
messages: Belongs to the type III secretion exporter family.

1163617:SCD RS06550
gene id: 1163617:SCD_RS06550
uniprot id: S6B3C0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

1163617:SCD RS12280
gene id: 1163617:SCD_RS12280
uniprot id: S6AJ42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1163617:SCD RS14970
gene id: 1163617:SCD_RS14970
uniprot id: S6ADZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1163617:SCD RS15205
gene id: 1163617:SCD_RS15205
uniprot id: S6AKD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1163617:SCD RS06905
gene id: 1163617:SCD_RS06905
uniprot id: S6AA45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

1163617:SCD RS05240
gene id: 1163617:SCD_RS05240
uniprot id: S6AG09
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1163617:SCD RS02570
gene id: 1163617:SCD_RS02570
uniprot id: S6AEW9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1163617:SCD RS08490
gene id: 1163617:SCD_RS08490
uniprot id: S6AAA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1163617:SCD RS02985
gene id: 1163617:SCD_RS02985
uniprot id: S6AB91
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1163617:SCD RS00010
gene id: 1163617:SCD_RS00010
uniprot id: S6AZA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1163617:SCD RS14530
gene id: 1163617:SCD_RS14530
uniprot id: S6ABG9
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1163617:SCD RS13550
gene id: 1163617:SCD_RS13550
uniprot id: S6ANS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1163617:SCD RS00210
gene id: 1163617:SCD_RS00210
uniprot id: S6A9C9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1163617:SCD RS00465
gene id: 1163617:SCD_RS00465
uniprot id: S6AAP8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1163617:SCD RS00190
gene id: 1163617:SCD_RS00190
uniprot id: S6ADX8
names: Similarity
messages: Belongs to the GARS family.

1163617:SCD RS05855
gene id: 1163617:SCD_RS05855
uniprot id: S6AG93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1163617:SCD RS05510
gene id: 1163617:SCD_RS05510
uniprot id: S6B2P5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1163617:SCD RS10805
gene id: 1163617:SCD_RS10805
uniprot id: S6ACY6
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1163617:SCD RS06245
gene id: 1163617:SCD_RS06245
uniprot id: S6ABX5
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

1163617:SCD RS06570
gene id: 1163617:SCD_RS06570
uniprot id: S6AGK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP M family.
messages: Cell inner membrane
messages: Membrane

1163617:SCD RS08505
gene id: 1163617:SCD_RS08505
uniprot id: S6ACF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1163617:SCD RS08030
gene id: 1163617:SCD_RS08030
uniprot id: S6ACB8
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1163617:SCD RS12035
gene id: 1163617:SCD_RS12035
uniprot id: S6AD74
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS08010
gene id: 1163617:SCD_RS08010
uniprot id: S6AL90
names: Similarity
messages: Belongs to the MotB family.

1163617:SCD RS03460
gene id: 1163617:SCD_RS03460
uniprot id: S6B1G2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1163617:SCD RS03090
gene id: 1163617:SCD_RS03090
uniprot id: S6AIU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1163617:SCD RS15260
gene id: 1163617:SCD_RS15260
uniprot id: S6B979
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

1163617:SCD RS09535
gene id: 1163617:SCD_RS09535
uniprot id: S6ACP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1163617:SCD RS14515
gene id: 1163617:SCD_RS14515
uniprot id: S6B8T7
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

1163617:SCD RS12930
gene id: 1163617:SCD_RS12930
uniprot id: S6AB02
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS00330
gene id: 1163617:SCD_RS00330
uniprot id: S6AHE9
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1163617:SCD RS10360
gene id: 1163617:SCD_RS10360
uniprot id: S6AAI2
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS10855
gene id: 1163617:SCD_RS10855
uniprot id: S6ACY9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1163617:SCD RS00945
gene id: 1163617:SCD_RS00945
uniprot id: S6A9F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

1163617:SCD RS05520
gene id: 1163617:SCD_RS05520
uniprot id: S6AK28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1163617:SCD RS03265
gene id: 1163617:SCD_RS03265
uniprot id: S6AIY3
names: Similarity
messages: Belongs to the ArsC family.

1163617:SCD RS05600
gene id: 1163617:SCD_RS05600
uniprot id: S6AK39
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS01660
gene id: 1163617:SCD_RS01660
uniprot id: S6A9I8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

1163617:SCD RS04680
gene id: 1163617:SCD_RS04680
uniprot id: S6AFT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1163617:SCD RS03750
gene id: 1163617:SCD_RS03750
uniprot id: S6B1P7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

1163617:SCD RS10590
gene id: 1163617:SCD_RS10590
uniprot id: S6ACX1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1163617:SCD RS09925
gene id: 1163617:SCD_RS09925
uniprot id: S6AI15
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1163617:SCD RS10895
gene id: 1163617:SCD_RS10895
uniprot id: S6B670
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

1163617:SCD RS03155
gene id: 1163617:SCD_RS03155
uniprot id: S6B1A2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1163617:SCD RS04375
gene id: 1163617:SCD_RS04375
uniprot id: S6AFQ6
names: Similarity
messages: Belongs to the TrpF family.

1163617:SCD RS06075
gene id: 1163617:SCD_RS06075
uniprot id: S6AA12
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1163617:SCD RS08215
gene id: 1163617:SCD_RS08215
uniprot id: S6AA97
names: Function
names: Similarity
messages: Belongs to the rhamnosyl O-methyltransferase family.
messages: Catalyzes the O-methylation of the hydroxyl group located on C-2 of the first rhamnosyl residue linked to the phenolic group of glycosylated phenolphthiocerol dimycocerosates (PGL) and p-hydroxybenzoic acid derivatives (p-HBAD).

1163617:SCD RS07315
gene id: 1163617:SCD_RS07315
uniprot id: S6AA61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1163617:SCD RS00485
gene id: 1163617:SCD_RS00485
uniprot id: S6AZL0
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1163617:SCD RS14590
gene id: 1163617:SCD_RS14590
uniprot id: S6B8U6
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

1163617:SCD RS00040
gene id: 1163617:SCD_RS00040
uniprot id: S6AZB3
names: Similarity
messages: Belongs to the DprA/Smf family.

1163617:SCD RS05990
gene id: 1163617:SCD_RS05990
uniprot id: S6ABV4
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1163617:SCD RS09340
gene id: 1163617:SCD_RS09340
uniprot id: S6ALW9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

1163617:SCD RS13740
gene id: 1163617:SCD_RS13740
uniprot id: S6AJN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane

1163617:SCD RS13920
gene id: 1163617:SCD_RS13920
uniprot id: S6ADN8
names: Similarity
messages: Belongs to the bacterial secretin family.

1163617:SCD RS05755
gene id: 1163617:SCD_RS05755
uniprot id: S6AA00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1163617:SCD RS07630
gene id: 1163617:SCD_RS07630
uniprot id: S6AC85
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1163617:SCD RS07360
gene id: 1163617:SCD_RS07360
uniprot id: S6AL22
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

1163617:SCD RS07145
gene id: 1163617:SCD_RS07145
uniprot id: S6AGV8
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS12085
gene id: 1163617:SCD_RS12085
uniprot id: S6AD78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1163617:SCD RS09780
gene id: 1163617:SCD_RS09780
uniprot id: S6B5H5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1163617:SCD RS06110
gene id: 1163617:SCD_RS06110
uniprot id: S6B332
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1163617:SCD RS14935
gene id: 1163617:SCD_RS14935
uniprot id: S6AKA5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1163617:SCD RS10930
gene id: 1163617:SCD_RS10930
uniprot id: S6AMI3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1163617:SCD RS14540
gene id: 1163617:SCD_RS14540
uniprot id: S6B8T9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility.
messages: Bacterial flagellum basal body
messages: Belongs to the YcgR family.
messages: Monomer. Interacts with the flagellar basal bodies.

1163617:SCD RS04075
gene id: 1163617:SCD_RS04075
uniprot id: S6AFJ6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163617:SCD RS05745
gene id: 1163617:SCD_RS05745
uniprot id: S6ABT5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1163617:SCD RS06210
gene id: 1163617:SCD_RS06210
uniprot id: S6AGE2
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1163617:SCD RS05505
gene id: 1163617:SCD_RS05505
uniprot id: S6AG47
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1163617:SCD RS12025
gene id: 1163617:SCD_RS12025
uniprot id: S6AJ07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

1163617:SCD RS04615
gene id: 1163617:SCD_RS04615
uniprot id: S6AJQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

1163617:SCD RS14210
gene id: 1163617:SCD_RS14210
uniprot id: S6B8I3
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1163617:SCD RS15050
gene id: 1163617:SCD_RS15050
uniprot id: S6AE01
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1163617:SCD RS04675
gene id: 1163617:SCD_RS04675
uniprot id: S6A9V7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1163617:SCD RS06115
gene id: 1163617:SCD_RS06115
uniprot id: S6ABW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1163617:SCD RS04210
gene id: 1163617:SCD_RS04210
uniprot id: S6AJJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1163617:SCD RS03815
gene id: 1163617:SCD_RS03815
uniprot id: S6A9S3
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

1163617:SCD RS12140
gene id: 1163617:SCD_RS12140
uniprot id: S6AD82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1163617:SCD RS06260
gene id: 1163617:SCD_RS06260
uniprot id: S6AGF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1163617:SCD RS03340
gene id: 1163617:SCD_RS03340
uniprot id: S6ABB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1163617:SCD RS02265
gene id: 1163617:SCD_RS02265
uniprot id: S6A9L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1163617:SCD RS14620
gene id: 1163617:SCD_RS14620
uniprot id: S6ADV4
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1163617:SCD RS08270
gene id: 1163617:SCD_RS08270
uniprot id: S6B4E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

1163617:SCD RS11995
gene id: 1163617:SCD_RS11995
uniprot id: S6AAU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

1163617:SCD RS13100
gene id: 1163617:SCD_RS13100
uniprot id: S6ANJ9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

1163617:SCD RS12765
gene id: 1163617:SCD_RS12765
uniprot id: S6ADD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1163617:SCD RS15860
gene id: 1163617:SCD_RS15860
uniprot id: S6AAX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1163617:SCD RS03310
gene id: 1163617:SCD_RS03310
uniprot id: S6B1D2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1163617:SCD RS12560
gene id: 1163617:SCD_RS12560
uniprot id: S6B7C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1163617:SCD RS08155
gene id: 1163617:SCD_RS08155
uniprot id: S6ACC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1163617:SCD RS07695
gene id: 1163617:SCD_RS07695
uniprot id: S6AA76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1163617:SCD RS05715
gene id: 1163617:SCD_RS05715
uniprot id: S6B2T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

1163617:SCD RS04755
gene id: 1163617:SCD_RS04755
uniprot id: S6AFU7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1163617:SCD RS08485
gene id: 1163617:SCD_RS08485
uniprot id: S6ALG5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1163617:SCD RS12265
gene id: 1163617:SCD_RS12265
uniprot id: S6AD93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1163617:SCD RS07795
gene id: 1163617:SCD_RS07795
uniprot id: S6AH28
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS05535
gene id: 1163617:SCD_RS05535
uniprot id: S6AG50
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1163617:SCD RS04165
gene id: 1163617:SCD_RS04165
uniprot id: S6AJH9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1163617:SCD RS01520
gene id: 1163617:SCD_RS01520
uniprot id: S6AEF6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1163617:SCD RS08920
gene id: 1163617:SCD_RS08920
uniprot id: S6ACI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1163617:SCD RS13435
gene id: 1163617:SCD_RS13435
uniprot id: K6VCL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm

1163617:SCD RS00030
gene id: 1163617:SCD_RS00030
uniprot id: S6A9C2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1163617:SCD RS09725
gene id: 1163617:SCD_RS09725
uniprot id: S6AHY9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1163617:SCD RS08765
gene id: 1163617:SCD_RS08765
uniprot id: S6ACH5
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1163617:SCD RS14075
gene id: 1163617:SCD_RS14075
uniprot id: S6ABB9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1163617:SCD RS08080
gene id: 1163617:SCD_RS08080
uniprot id: S6ACC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1163617:SCD RS03945
gene id: 1163617:SCD_RS03945
uniprot id: S6A9S8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

1163617:SCD RS12660
gene id: 1163617:SCD_RS12660
uniprot id: S6B7E4
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

1163617:SCD RS03055
gene id: 1163617:SCD_RS03055
uniprot id: S6B183
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1163617:SCD RS07410
gene id: 1163617:SCD_RS07410
uniprot id: S6AL26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

1163617:SCD RS07355
gene id: 1163617:SCD_RS07355
uniprot id: S6AC64
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.

1163617:SCD RS03325
gene id: 1163617:SCD_RS03325
uniprot id: S6A9Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1163617:SCD RS08085
gene id: 1163617:SCD_RS08085
uniprot id: S6ALA0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163617:SCD RS00700
gene id: 1163617:SCD_RS00700
uniprot id: S6AE42
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS00080
gene id: 1163617:SCD_RS00080
uniprot id: S6A9C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell.

1163617:SCD RS11700
gene id: 1163617:SCD_RS11700
uniprot id: S6AD51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

1163617:SCD RS12095
gene id: 1163617:SCD_RS12095
uniprot id: S6AN61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1163617:SCD RS13090
gene id: 1163617:SCD_RS13090
uniprot id: S6AJD9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

1163617:SCD RS07245
gene id: 1163617:SCD_RS07245
uniprot id: S6AGW9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

1163617:SCD RS07190
gene id: 1163617:SCD_RS07190
uniprot id: S6AA56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1163617:SCD RS12220
gene id: 1163617:SCD_RS12220
uniprot id: S6AN76
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1163617:SCD RS04335
gene id: 1163617:SCD_RS04335
uniprot id: S6ABH5
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS09730
gene id: 1163617:SCD_RS09730
uniprot id: S6B5G4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1163617:SCD RS07240
gene id: 1163617:SCD_RS07240
uniprot id: S6AA58
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1163617:SCD RS02990
gene id: 1163617:SCD_RS02990
uniprot id: S6AIS9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1163617:SCD RS07705
gene id: 1163617:SCD_RS07705
uniprot id: S6B418
names: Similarity
messages: Belongs to the YjdM family.

1163617:SCD RS00025
gene id: 1163617:SCD_RS00025
uniprot id: S6AHA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1163617:SCD RS03355
gene id: 1163617:SCD_RS03355
uniprot id: S6AF68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1163617:SCD RS01105
gene id: 1163617:SCD_RS01105
uniprot id: S6AZZ7
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1163617:SCD RS08400
gene id: 1163617:SCD_RS08400
uniprot id: S6B4I2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

1163617:SCD RS07595
gene id: 1163617:SCD_RS07595
uniprot id: S6AH07
names: Similarity
messages: Belongs to the fabD family.

1163617:SCD RS07415
gene id: 1163617:SCD_RS07415
uniprot id: S6AA65
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

1163617:SCD RS08895
gene id: 1163617:SCD_RS08895
uniprot id: S6ACI6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1163617:SCD RS13355
gene id: 1163617:SCD_RS13355
uniprot id: S6AB35
names: Similarity
messages: Belongs to the peptidase S41A family.

1163617:SCD RS14535
gene id: 1163617:SCD_RS14535
uniprot id: S6AK55
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1163617:SCD RS13745
gene id: 1163617:SCD_RS13745
uniprot id: S6B829
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1163617:SCD RS14680
gene id: 1163617:SCD_RS14680
uniprot id: S6ABH8
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS07890
gene id: 1163617:SCD_RS07890
uniprot id: S6AA84
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

1163617:SCD RS07425
gene id: 1163617:SCD_RS07425
uniprot id: S6B3V6
names: Similarity
messages: Belongs to the citrate synthase family.

1163617:SCD RS10150
gene id: 1163617:SCD_RS10150
uniprot id: S6ACU0
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS00240
gene id: 1163617:SCD_RS00240
uniprot id: S6ADY4
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

1163617:SCD RS08850
gene id: 1163617:SCD_RS08850
uniprot id: S6ALM8
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

1163617:SCD RS12620
gene id: 1163617:SCD_RS12620
uniprot id: S6AND1
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Oligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.

1163617:SCD RS03145
gene id: 1163617:SCD_RS03145
uniprot id: S6A9P6
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1163617:SCD RS11000
gene id: 1163617:SCD_RS11000
uniprot id: S6B694
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1163617:SCD RS13185
gene id: 1163617:SCD_RS13185
uniprot id: S6AJF1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1163617:SCD RS00440
gene id: 1163617:SCD_RS00440
uniprot id: S6AAP6
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS01405
gene id: 1163617:SCD_RS01405
uniprot id: S6AAX5
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1163617:SCD RS10555
gene id: 1163617:SCD_RS10555
uniprot id: S6AI89
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

1163617:SCD RS01500
gene id: 1163617:SCD_RS01500
uniprot id: S6AEF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

1163617:SCD RS01020
gene id: 1163617:SCD_RS01020
uniprot id: S6A9G2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1163617:SCD RS09275
gene id: 1163617:SCD_RS09275
uniprot id: S6AHQ6
names: Subcellular Location Annotation
messages: Cytoplasm

1163617:SCD RS14240
gene id: 1163617:SCD_RS14240
uniprot id: S6ADR2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1163617:SCD RS12570
gene id: 1163617:SCD_RS12570
uniprot id: S6ANC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

1163617:SCD RS05110
gene id: 1163617:SCD_RS05110
uniprot id: S6AFZ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1163617:SCD RS01855
gene id: 1163617:SCD_RS01855
uniprot id: S6AI87
names: Similarity
messages: Belongs to the Ahb/Nir family.

1163617:SCD RS12770
gene id: 1163617:SCD_RS12770
uniprot id: S6ANF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1163617:SCD RS01935
gene id: 1163617:SCD_RS01935
uniprot id: S6AIA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1163617:SCD RS05880
gene id: 1163617:SCD_RS05880
uniprot id: S6AG96
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: In the C-terminal section; belongs to the transglycosylase Slt family.
messages: In the N-terminal section; belongs to the bacterial solute-binding protein 3 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
messages: The N-terminal domain does not have lytic activity and probably modulates enzymatic activity. The C-terminal domain is the catalytic active domain.

1163617:SCD RS10825
gene id: 1163617:SCD_RS10825
uniprot id: S6B654
names: Similarity
messages: Belongs to the UPF0234 family.

1163617:SCD RS05200
gene id: 1163617:SCD_RS05200
uniprot id: S6AJY5
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

1163617:SCD RS04535
gene id: 1163617:SCD_RS04535
uniprot id: S6ABJ3
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1163617:SCD RS11370
gene id: 1163617:SCD_RS11370
uniprot id: S6AIN0
names: Similarity
messages: Belongs to the GSP E family.

1163617:SCD RS00490
gene id: 1163617:SCD_RS00490
uniprot id: S6AAQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1163617:SCD RS12100
gene id: 1163617:SCD_RS12100
uniprot id: S6AAU9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1163617:SCD RS12960
gene id: 1163617:SCD_RS12960
uniprot id: S6AJC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1163617:SCD RS10925
gene id: 1163617:SCD_RS10925
uniprot id: S6ACZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

1163617:SCD RS07470
gene id: 1163617:SCD_RS07470
uniprot id: S6AGZ4
names: Similarity
messages: Belongs to the DEAD box helicase family.

1163617:SCD RS09965
gene id: 1163617:SCD_RS09965
uniprot id: S6AI22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1163617:SCD RS10430
gene id: 1163617:SCD_RS10430
uniprot id: S6ACW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1163617:SCD RS02580
gene id: 1163617:SCD_RS02580
uniprot id: S6AB66
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1163617:SCD RS05840
gene id: 1163617:SCD_RS05840
uniprot id: S6AK85
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1163617:SCD RS05260
gene id: 1163617:SCD_RS05260
uniprot id: S6A9Y1
names: Similarity
messages: Belongs to the aspartokinase family.

1163617:SCD RS05115
gene id: 1163617:SCD_RS05115
uniprot id: S6B2H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1163617:SCD RS02670
gene id: 1163617:SCD_RS02670
uniprot id: S6A9M8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1163617:SCD RS08345
gene id: 1163617:SCD_RS08345
uniprot id: S6ACE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1163617:SCD RS03825
gene id: 1163617:SCD_RS03825
uniprot id: S6B1R3
names: Function
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.

1163617:SCD RS02830
gene id: 1163617:SCD_RS02830
uniprot id: S6B141
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1163617:SCD RS03075
gene id: 1163617:SCD_RS03075
uniprot id: S6AF34
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1163617:SCD RS07075
gene id: 1163617:SCD_RS07075
uniprot id: S6B3Q0
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1163617:SCD RS05975
gene id: 1163617:SCD_RS05975
uniprot id: S6AA08
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS00500
gene id: 1163617:SCD_RS00500
uniprot id: S6A9E1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1163617:SCD RS09900
gene id: 1163617:SCD_RS09900
uniprot id: S6AI11
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS11010
gene id: 1163617:SCD_RS11010
uniprot id: S6AMJ8
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS10785
gene id: 1163617:SCD_RS10785
uniprot id: S6AMF8
names: Subcellular Location Annotation
messages: Cytoplasm

1163617:SCD RS09750
gene id: 1163617:SCD_RS09750
uniprot id: S6AHZ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1163617:SCD RS14045
gene id: 1163617:SCD_RS14045
uniprot id: S6AP13
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.

1163617:SCD RS04715
gene id: 1163617:SCD_RS04715
uniprot id: S6ABK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1163617:SCD RS12950
gene id: 1163617:SCD_RS12950
uniprot id: S6ANH5
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1163617:SCD RS03180
gene id: 1163617:SCD_RS03180
uniprot id: S6B1A7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1163617:SCD RS08020
gene id: 1163617:SCD_RS08020
uniprot id: S6AH53
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS06990
gene id: 1163617:SCD_RS06990
uniprot id: S6B3N9
names: Similarity
messages: Belongs to the peptidase S16 family.

1163617:SCD RS05405
gene id: 1163617:SCD_RS05405
uniprot id: S6ABQ8
names: Similarity
messages: Belongs to the peptidase S24 family.

1163617:SCD RS00220
gene id: 1163617:SCD_RS00220
uniprot id: S6AZF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

1163617:SCD RS03540
gene id: 1163617:SCD_RS03540
uniprot id: S6ABC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1163617:SCD RS13775
gene id: 1163617:SCD_RS13775
uniprot id: S6ADM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1163617:SCD RS08785
gene id: 1163617:SCD_RS08785
uniprot id: S6B4S7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1163617:SCD RS06610
gene id: 1163617:SCD_RS06610
uniprot id: S6AA33
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1163617:SCD RS09110
gene id: 1163617:SCD_RS09110
uniprot id: S6B510
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

1163617:SCD RS09045
gene id: 1163617:SCD_RS09045
uniprot id: S6ALR7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1163617:SCD RS09220
gene id: 1163617:SCD_RS09220
uniprot id: S6AAD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1163617:SCD RS09655
gene id: 1163617:SCD_RS09655
uniprot id: S6B5F0
names: Similarity
messages: Belongs to the GSP E family.

1163617:SCD RS02515
gene id: 1163617:SCD_RS02515
uniprot id: S6A9M2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

1163617:SCD RS02325
gene id: 1163617:SCD_RS02325
uniprot id: S6B0V5
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1163617:SCD RS11895
gene id: 1163617:SCD_RS11895
uniprot id: S6AAT1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1163617:SCD RS07615
gene id: 1163617:SCD_RS07615
uniprot id: S6AA73
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

1163617:SCD RS12000
gene id: 1163617:SCD_RS12000
uniprot id: S6AJ03
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

1163617:SCD RS11940
gene id: 1163617:SCD_RS11940
uniprot id: S6AD69
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1163617:SCD RS00060
gene id: 1163617:SCD_RS00060
uniprot id: S6ADW2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1163617:SCD RS00015
gene id: 1163617:SCD_RS00015
uniprot id: S6AAL6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1163617:SCD RS13540
gene id: 1163617:SCD_RS13540
uniprot id: S6B7Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1163617:SCD RS04355
gene id: 1163617:SCD_RS04355
uniprot id: S6B242
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163617:SCD RS03510
gene id: 1163617:SCD_RS03510
uniprot id: S6B1H4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

1163617:SCD RS10620
gene id: 1163617:SCD_RS10620
uniprot id: S6AMD4
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

1163617:SCD RS05155
gene id: 1163617:SCD_RS05155
uniprot id: S6A9X7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

1163617:SCD RS09605
gene id: 1163617:SCD_RS09605
uniprot id: S6B5E0
names: Similarity
messages: Belongs to the UPF0225 family.

1163617:SCD RS10480
gene id: 1163617:SCD_RS10480
uniprot id: S6B5X2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1163617:SCD RS01850
gene id: 1163617:SCD_RS01850
uniprot id: S6AB20
names: Similarity
messages: Belongs to the Ahb/Nir family.

1163617:SCD RS00455
gene id: 1163617:SCD_RS00455
uniprot id: S6AE12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

1163617:SCD RS06555
gene id: 1163617:SCD_RS06555
uniprot id: S6ABZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

1163617:SCD RS04160
gene id: 1163617:SCD_RS04160
uniprot id: S6ABG1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163617:SCD RS06160
gene id: 1163617:SCD_RS06160
uniprot id: S6B345
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1163617:SCD RS00995
gene id: 1163617:SCD_RS00995
uniprot id: S6A9G1
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1163617:SCD RS09995
gene id: 1163617:SCD_RS09995
uniprot id: S6B5L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1163617:SCD RS04370
gene id: 1163617:SCD_RS04370
uniprot id: S6A9U5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163617:SCD RS09765
gene id: 1163617:SCD_RS09765
uniprot id: S6AM30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1163617:SCD RS05380
gene id: 1163617:SCD_RS05380
uniprot id: S6ABQ6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1163617:SCD RS04550
gene id: 1163617:SCD_RS04550
uniprot id: S6AFS6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

1163617:SCD RS12700
gene id: 1163617:SCD_RS12700
uniprot id: S6AAY6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1163617:SCD RS03590
gene id: 1163617:SCD_RS03590
uniprot id: S6AJ35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1163617:SCD RS06100
gene id: 1163617:SCD_RS06100
uniprot id: S6AA13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

1163617:SCD RS12605
gene id: 1163617:SCD_RS12605
uniprot id: S6AJ78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1163617:SCD RS04135
gene id: 1163617:SCD_RS04135
uniprot id: S6ABG0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1163617:SCD RS13030
gene id: 1163617:SCD_RS13030
uniprot id: S6ANI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1163617:SCD RS09330
gene id: 1163617:SCD_RS09330
uniprot id: S6B562
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1163617:SCD RS06700
gene id: 1163617:SCD_RS06700
uniprot id: S6AC10
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

1163617:SCD RS01595
gene id: 1163617:SCD_RS01595
uniprot id: S6AEG8
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS01005
gene id: 1163617:SCD_RS01005
uniprot id: S6AZX5
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS10415
gene id: 1163617:SCD_RS10415
uniprot id: S6AAI4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1163617:SCD RS11900
gene id: 1163617:SCD_RS11900
uniprot id: S6AIY2
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1163617:SCD RS12190
gene id: 1163617:SCD_RS12190
uniprot id: S6AD86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1163617:SCD RS09350
gene id: 1163617:SCD_RS09350
uniprot id: S6AHS3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1163617:SCD RS03250
gene id: 1163617:SCD_RS03250
uniprot id: S6AF57
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1163617:SCD RS02910
gene id: 1163617:SCD_RS02910
uniprot id: S6AB86
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1163617:SCD RS12250
gene id: 1163617:SCD_RS12250
uniprot id: S6AAV8
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1163617:SCD RS09760
gene id: 1163617:SCD_RS09760
uniprot id: S6ACR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1163617:SCD RS11395
gene id: 1163617:SCD_RS11395
uniprot id: S6AIN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1163617:SCD RS06140
gene id: 1163617:SCD_RS06140
uniprot id: S6ABW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1163617:SCD RS08500
gene id: 1163617:SCD_RS08500
uniprot id: S6B4L2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1163617:SCD RS05540
gene id: 1163617:SCD_RS05540
uniprot id: S6B2P9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1163617:SCD RS14400
gene id: 1163617:SCD_RS14400
uniprot id: S6AP88
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1163617:SCD RS00470
gene id: 1163617:SCD_RS00470
uniprot id: S6AHG8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1163617:SCD RS01400
gene id: 1163617:SCD_RS01400
uniprot id: S6B068
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

1163617:SCD RS09865
gene id: 1163617:SCD_RS09865
uniprot id: S6AM41
names: Similarity
messages: Belongs to the universal stress protein A family.

1163617:SCD RS06970
gene id: 1163617:SCD_RS06970
uniprot id: S6AC38
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1163617:SCD RS09905
gene id: 1163617:SCD_RS09905
uniprot id: S6B5K0
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS09015
gene id: 1163617:SCD_RS09015
uniprot id: S6B4Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1163617:SCD RS03285
gene id: 1163617:SCD_RS03285
uniprot id: S6B1C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1163617:SCD RS03440
gene id: 1163617:SCD_RS03440
uniprot id: S6ABB7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1163617:SCD RS14960
gene id: 1163617:SCD_RS14960
uniprot id: S6AKA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1163617:SCD RS09950
gene id: 1163617:SCD_RS09950
uniprot id: S6ACS7
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS09195
gene id: 1163617:SCD_RS09195
uniprot id: S6AAD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1163617:SCD RS00195
gene id: 1163617:SCD_RS00195
uniprot id: S6AZE6
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1163617:SCD RS04065
gene id: 1163617:SCD_RS04065
uniprot id: S6AJF4
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1163617:SCD RS11210
gene id: 1163617:SCD_RS11210
uniprot id: S6AMN5
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1163617:SCD RS02535
gene id: 1163617:SCD_RS02535
uniprot id: S6AIK6
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1163617:SCD RS06240
gene id: 1163617:SCD_RS06240
uniprot id: S6B360
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

1163617:SCD RS14850
gene id: 1163617:SCD_RS14850
uniprot id: S6APF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1163617:SCD RS06275
gene id: 1163617:SCD_RS06275
uniprot id: S6AKG2
names: Similarity
messages: Belongs to the ParA family. MinD subfamily.

1163617:SCD RS04685
gene id: 1163617:SCD_RS04685
uniprot id: S6B299
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1163617:SCD RS11990
gene id: 1163617:SCD_RS11990
uniprot id: S6AN48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1163617:SCD RS12845
gene id: 1163617:SCD_RS12845
uniprot id: S6ADE4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1163617:SCD RS03435
gene id: 1163617:SCD_RS03435
uniprot id: S6B1F8
names: Similarity
messages: Belongs to the peptidase S11 family.

1163617:SCD RS12365
gene id: 1163617:SCD_RS12365
uniprot id: S6ADA4
names: Similarity
messages: Belongs to the UPF0102 family.

1163617:SCD RS06695
gene id: 1163617:SCD_RS06695
uniprot id: S6B3F3
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163617:SCD RS04150
gene id: 1163617:SCD_RS04150
uniprot id: S6AFK9
names: Similarity
messages: Belongs to the UPF0307 family.

1163617:SCD RS13785
gene id: 1163617:SCD_RS13785
uniprot id: S6AB85
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1163617:SCD RS04425
gene id: 1163617:SCD_RS04425
uniprot id: S6AFR1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

1163617:SCD RS07790
gene id: 1163617:SCD_RS07790
uniprot id: S6AA80
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

1163617:SCD RS00150
gene id: 1163617:SCD_RS00150
uniprot id: S6AAM5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163617:SCD RS03040
gene id: 1163617:SCD_RS03040
uniprot id: S6AIT4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163617:SCD RS12430
gene id: 1163617:SCD_RS12430
uniprot id: S6AJ58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1163617:SCD RS13335
gene id: 1163617:SCD_RS13335
uniprot id: S6AJH4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1163617:SCD RS01570
gene id: 1163617:SCD_RS01570
uniprot id: S6AEG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1163617:SCD RS11185
gene id: 1163617:SCD_RS11185
uniprot id: S6AMN0
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163617:SCD RS02940
gene id: 1163617:SCD_RS02940
uniprot id: S6AIR8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1163617:SCD RS06845
gene id: 1163617:SCD_RS06845
uniprot id: S6B3I7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

1163617:SCD RS01805
gene id: 1163617:SCD_RS01805
uniprot id: S6AI66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapD family.
messages: Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

1163617:SCD RS01420
gene id: 1163617:SCD_RS01420
uniprot id: S6AEE5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163617:SCD RS03900
gene id: 1163617:SCD_RS03900
uniprot id: S6AFG3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163617:SCD RS12205
gene id: 1163617:SCD_RS12205
uniprot id: S6AJ33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.

1163617:SCD RS15010
gene id: 1163617:SCD_RS15010
uniprot id: S6AKB5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163617:SCD RS08695
gene id: 1163617:SCD_RS08695
uniprot id: S6AHE7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163617:SCD RS02065
gene id: 1163617:SCD_RS02065
uniprot id: S6A9K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPS (TC 1.B.20) family.
messages: Cell outer membrane
messages: Membrane

1163617:SCD RS03765
gene id: 1163617:SCD_RS03765
uniprot id: S6A9S1
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS09975
gene id: 1163617:SCD_RS09975
uniprot id: S6ACS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1163617:SCD RS04345
gene id: 1163617:SCD_RS04345
uniprot id: S6A9U4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1163617:SCD RS07030
gene id: 1163617:SCD_RS07030
uniprot id: S6AC42
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1163617:SCD RS04545
gene id: 1163617:SCD_RS04545
uniprot id: S6A9V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1163617:SCD RS10275
gene id: 1163617:SCD_RS10275
uniprot id: S6ACV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1163617:SCD RS09265
gene id: 1163617:SCD_RS09265
uniprot id: S6ALV7
names: Similarity
messages: Belongs to the acylphosphatase family.

1163617:SCD RS00265
gene id: 1163617:SCD_RS00265
uniprot id: S6ADY7
names: Similarity
messages: Belongs to the phosphoribulokinase family.

1163617:SCD RS00145
gene id: 1163617:SCD_RS00145
uniprot id: S6AZD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1163617:SCD RS13345
gene id: 1163617:SCD_RS13345
uniprot id: S6ADI6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1163617:SCD RS03720
gene id: 1163617:SCD_RS03720
uniprot id: S6AFD4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163617:SCD RS06400
gene id: 1163617:SCD_RS06400
uniprot id: S6AKJ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1163617:SCD RS06860
gene id: 1163617:SCD_RS06860
uniprot id: S6AA43
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1163617:SCD RS05490
gene id: 1163617:SCD_RS05490
uniprot id: S6ABR4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1163617:SCD RS06940
gene id: 1163617:SCD_RS06940
uniprot id: S6B3N1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

1163617:SCD RS13175
gene id: 1163617:SCD_RS13175
uniprot id: S6ANL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
messages: Cytoplasm
messages: Monomer.
messages: The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.

1163617:SCD RS03300
gene id: 1163617:SCD_RS03300
uniprot id: S6A9Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

1163617:SCD RS07855
gene id: 1163617:SCD_RS07855
uniprot id: S6ACA4
names: Similarity
messages: Belongs to the PhoH family.

1163617:SCD RS03105
gene id: 1163617:SCD_RS03105
uniprot id: S6B193
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1163617:SCD RS03210
gene id: 1163617:SCD_RS03210
uniprot id: S6ABA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1163617:SCD RS00275
gene id: 1163617:SCD_RS00275
uniprot id: S6AAN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

1163617:SCD RS00530
gene id: 1163617:SCD_RS00530
uniprot id: S6AE21
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1163617:SCD RS03220
gene id: 1163617:SCD_RS03220
uniprot id: S6A9P9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1163617:SCD RS04225
gene id: 1163617:SCD_RS04225
uniprot id: S6B205
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1163617:SCD RS09230
gene id: 1163617:SCD_RS09230
uniprot id: S6B537
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1163617:SCD RS00095
gene id: 1163617:SCD_RS00095
uniprot id: S6AAM2
names: Similarity
messages: Belongs to the peptidase M1 family.

1163617:SCD RS05610
gene id: 1163617:SCD_RS05610
uniprot id: S6B2R5
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS07920
gene id: 1163617:SCD_RS07920
uniprot id: S6AH41
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

1163617:SCD RS03350
gene id: 1163617:SCD_RS03350
uniprot id: S6A9Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1163617:SCD RS13285
gene id: 1163617:SCD_RS13285
uniprot id: S6AJG6
names: Similarity
messages: Belongs to the GSP E family.

1163617:SCD RS06155
gene id: 1163617:SCD_RS06155
uniprot id: S6AGD3
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1163617:SCD RS13525
gene id: 1163617:SCD_RS13525
uniprot id: S6ANR9
names: Similarity
messages: Belongs to the thioredoxin family. DsbE subfamily.

1163617:SCD RS09510
gene id: 1163617:SCD_RS09510
uniprot id: S6ACP6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1163617:SCD RS14945
gene id: 1163617:SCD_RS14945
uniprot id: S6ADY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1163617:SCD RS12030
gene id: 1163617:SCD_RS12030
uniprot id: S6B712
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1163617:SCD RS05700
gene id: 1163617:SCD_RS05700
uniprot id: K6V474
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

1163617:SCD RS10575
gene id: 1163617:SCD_RS10575
uniprot id: S6AAJ0
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

1163617:SCD RS04605
gene id: 1163617:SCD_RS04605
uniprot id: S6B288
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1163617:SCD RS03000
gene id: 1163617:SCD_RS03000
uniprot id: S6AF27
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

1163617:SCD RS10095
gene id: 1163617:SCD_RS10095
uniprot id: S6B5N3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1163617:SCD RS02925
gene id: 1163617:SCD_RS02925
uniprot id: S6AF17
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1163617:SCD RS07365
gene id: 1163617:SCD_RS07365
uniprot id: S6AA63
names: Similarity
messages: Belongs to the ArsC family.

1163617:SCD RS14455
gene id: 1163617:SCD_RS14455
uniprot id: S6ABG2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1163617:SCD RS07440
gene id: 1163617:SCD_RS07440
uniprot id: S6AA66
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1163617:SCD RS03335
gene id: 1163617:SCD_RS03335
uniprot id: S6B1D7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1163617:SCD RS12510
gene id: 1163617:SCD_RS12510
uniprot id: S6B7B3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163617:SCD RS07300
gene id: 1163617:SCD_RS07300
uniprot id: S6B3T7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

1163617:SCD RS13420
gene id: 1163617:SCD_RS13420
uniprot id: K6UH29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

1163617:SCD RS13290
gene id: 1163617:SCD_RS13290
uniprot id: S6B7S7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1163617:SCD RS04465
gene id: 1163617:SCD_RS04465
uniprot id: S6AJN9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1163617:SCD RS09530
gene id: 1163617:SCD_RS09530
uniprot id: S6B5C7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1163617:SCD RS13295
gene id: 1163617:SCD_RS13295
uniprot id: S6ADI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1163617:SCD RS00935
gene id: 1163617:SCD_RS00935
uniprot id: S6AAT2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1163617:SCD RS08570
gene id: 1163617:SCD_RS08570
uniprot id: S6AHC2
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

1163617:SCD RS06305
gene id: 1163617:SCD_RS06305
uniprot id: S6AA21
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

1163617:SCD RS09000
gene id: 1163617:SCD_RS09000
uniprot id: S6ALQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1163617:SCD RS07230
gene id: 1163617:SCD_RS07230
uniprot id: S6AC55
names: Similarity
messages: Belongs to the UPF0166 family.

1163617:SCD RS06205
gene id: 1163617:SCD_RS06205
uniprot id: S6AA17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

1163617:SCD RS09555
gene id: 1163617:SCD_RS09555
uniprot id: S6B5D1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1163617:SCD RS02530
gene id: 1163617:SCD_RS02530
uniprot id: S6AB63
names: Similarity
messages: Belongs to the RutC family.

1163617:SCD RS11650
gene id: 1163617:SCD_RS11650
uniprot id: S6AD48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1163617:SCD RS08265
gene id: 1163617:SCD_RS08265
uniprot id: S6AH82
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1163617:SCD RS07820
gene id: 1163617:SCD_RS07820
uniprot id: S6AH32
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

1163617:SCD RS07570
gene id: 1163617:SCD_RS07570
uniprot id: S6AH04
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1163617:SCD RS01135
gene id: 1163617:SCD_RS01135
uniprot id: S6AAU5
names: Similarity
messages: Belongs to the GSP E family.

1163617:SCD RS12465
gene id: 1163617:SCD_RS12465
uniprot id: S6ADB0
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1163617:SCD RS08225
gene id: 1163617:SCD_RS08225
uniprot id: S6B4D7
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage.

1163617:SCD RS04170
gene id: 1163617:SCD_RS04170
uniprot id: S6A9T7
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1163617:SCD RS12565
gene id: 1163617:SCD_RS12565
uniprot id: S6ADB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1163617:SCD RS04045
gene id: 1163617:SCD_RS04045
uniprot id: S6A9T2
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS08090
gene id: 1163617:SCD_RS08090
uniprot id: S6AA92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1163617:SCD RS12535
gene id: 1163617:SCD_RS12535
uniprot id: S6B7C0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1163617:SCD RS03485
gene id: 1163617:SCD_RS03485
uniprot id: S6B1G7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1163617:SCD RS08065
gene id: 1163617:SCD_RS08065
uniprot id: S6AA91
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163617:SCD RS08560
gene id: 1163617:SCD_RS08560
uniprot id: S6ALH5
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

1163617:SCD RS10920
gene id: 1163617:SCD_RS10920
uniprot id: S6B677
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1163617:SCD RS00205
gene id: 1163617:SCD_RS00205
uniprot id: S6AHD2
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1163617:SCD RS02510
gene id: 1163617:SCD_RS02510
uniprot id: S6AIK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

1163617:SCD RS12320
gene id: 1163617:SCD_RS12320
uniprot id: S6AN88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1163617:SCD RS02975
gene id: 1163617:SCD_RS02975
uniprot id: S6AF24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

1163617:SCD RS05145
gene id: 1163617:SCD_RS05145
uniprot id: S6ABP0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1163617:SCD RS12165
gene id: 1163617:SCD_RS12165
uniprot id: S6AD84
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1163617:SCD RS01415
gene id: 1163617:SCD_RS01415
uniprot id: S6A9H8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

1163617:SCD RS10910
gene id: 1163617:SCD_RS10910
uniprot id: S6AAK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1163617:SCD RS10050
gene id: 1163617:SCD_RS10050
uniprot id: S6ACT3
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO small chain family.
messages: Heterohexadecamer of 8 large and 8 small subunits.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site. Although the small subunit is not catalytic it is essential for maximal activity.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.

1163617:SCD RS12370
gene id: 1163617:SCD_RS12370
uniprot id: S6AN96
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

1163617:SCD RS05095
gene id: 1163617:SCD_RS05095
uniprot id: S6ABN6
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1163617:SCD RS11390
gene id: 1163617:SCD_RS11390
uniprot id: S6AAN3
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1163617:SCD RS14965
gene id: 1163617:SCD_RS14965
uniprot id: S6B924
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1163617:SCD RS11245
gene id: 1163617:SCD_RS11245
uniprot id: S6AAL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1163617:SCD RS12125
gene id: 1163617:SCD_RS12125
uniprot id: S6AAV0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably interacts with PlsX.

1163617:SCD RS10110
gene id: 1163617:SCD_RS10110
uniprot id: S6AAH2
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1163617:SCD RS09355
gene id: 1163617:SCD_RS09355
uniprot id: S6B569
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1163617:SCD RS00185
gene id: 1163617:SCD_RS00185
uniprot id: S6A9C8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

1163617:SCD RS09240
gene id: 1163617:SCD_RS09240
uniprot id: S6ALV3
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1163617:SCD RS05435
gene id: 1163617:SCD_RS05435
uniprot id: S6ABR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1163617:SCD RS09645
gene id: 1163617:SCD_RS09645
uniprot id: S6AAF3
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1163617:SCD RS10250
gene id: 1163617:SCD_RS10250
uniprot id: S6ACU8
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

1163617:SCD RS02430
gene id: 1163617:SCD_RS02430
uniprot id: S6AB57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1163617:SCD RS12530
gene id: 1163617:SCD_RS12530
uniprot id: S6AJ69
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

1163617:SCD RS07590
gene id: 1163617:SCD_RS07590
uniprot id: S6AA72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1163617:SCD RS08340
gene id: 1163617:SCD_RS08340
uniprot id: S6B4G7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1163617:SCD RS08025
gene id: 1163617:SCD_RS08025
uniprot id: S6B494
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1163617:SCD RS13710
gene id: 1163617:SCD_RS13710
uniprot id: S6AB76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

1163617:SCD RS06985
gene id: 1163617:SCD_RS06985
uniprot id: S6AGU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

1163617:SCD RS10160
gene id: 1163617:SCD_RS10160
uniprot id: S6AAH4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1163617:SCD RS09800
gene id: 1163617:SCD_RS09800
uniprot id: S6AHZ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1163617:SCD RS05140
gene id: 1163617:SCD_RS05140
uniprot id: S6B2H8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1163617:SCD RS05470
gene id: 1163617:SCD_RS05470
uniprot id: S6A9Y9
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1163617:SCD RS04140
gene id: 1163617:SCD_RS04140
uniprot id: S6AJH3
names: Similarity
messages: Belongs to the hemerythrin family.

1163617:SCD RS12505
gene id: 1163617:SCD_RS12505
uniprot id: S6AJ67
names: Similarity
messages: Belongs to the TrpC family.

1163617:SCD RS12445
gene id: 1163617:SCD_RS12445
uniprot id: S6ANA4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters.

1163617:SCD RS10425
gene id: 1163617:SCD_RS10425
uniprot id: S6B5W1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1163617:SCD RS03740
gene id: 1163617:SCD_RS03740
uniprot id: S6A9S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1163617:SCD RS07770
gene id: 1163617:SCD_RS07770
uniprot id: S6AA79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1163617:SCD RS06420
gene id: 1163617:SCD_RS06420
uniprot id: S6ABY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1163617:SCD RS11625
gene id: 1163617:SCD_RS11625
uniprot id: S6AD46
names: Similarity
messages: Belongs to the thioredoxin family.

1163617:SCD RS11020
gene id: 1163617:SCD_RS11020
uniprot id: S6AIH3
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

1163617:SCD RS06475
gene id: 1163617:SCD_RS06475
uniprot id: S6ABZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1163617:SCD RS06895
gene id: 1163617:SCD_RS06895
uniprot id: S6AC32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

1163617:SCD RS04470
gene id: 1163617:SCD_RS04470
uniprot id: S6A9U9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1163617:SCD RS00850
gene id: 1163617:SCD_RS00850
uniprot id: S6AE62
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

1163617:SCD RS07045
gene id: 1163617:SCD_RS07045
uniprot id: S6AGU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1163617:SCD RS08405
gene id: 1163617:SCD_RS08405
uniprot id: S6ACE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1163617:SCD RS15115
gene id: 1163617:SCD_RS15115
uniprot id: S6ABL3
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

1163617:SCD RS10090
gene id: 1163617:SCD_RS10090
uniprot id: S6AI35
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1163617:SCD RS07865
gene id: 1163617:SCD_RS07865
uniprot id: S6AA83
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1163617:SCD RS13055
gene id: 1163617:SCD_RS13055
uniprot id: S6ANJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

1163617:SCD RS03515
gene id: 1163617:SCD_RS03515
uniprot id: S6ABC1
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1163617:SCD RS03045
gene id: 1163617:SCD_RS03045
uniprot id: S6A9P2
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1163617:SCD RS15960
gene id: 1163617:SCD_RS15960
uniprot id: S6ABP1
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1163617:SCD RS03805
gene id: 1163617:SCD_RS03805
uniprot id: S6ABD9
names: Similarity
messages: Belongs to the HupF/HypC family.

1163617:SCD RS08095
gene id: 1163617:SCD_RS08095
uniprot id: S6AH62
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1163617:SCD RS06565
gene id: 1163617:SCD_RS06565
uniprot id: S6AA31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP L family.
messages: Cell inner membrane
messages: Membrane

1163617:SCD RS02315
gene id: 1163617:SCD_RS02315
uniprot id: S6A9L4
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1163617:SCD RS09290
gene id: 1163617:SCD_RS09290
uniprot id: S6ALW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

1163617:SCD RS10985
gene id: 1163617:SCD_RS10985
uniprot id: S6AMJ3
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1163617:SCD RS12900
gene id: 1163617:SCD_RS12900
uniprot id: S6ADE8
names: Similarity
messages: Belongs to the Gfa family.

1163617:SCD RS08905
gene id: 1163617:SCD_RS08905
uniprot id: S6AAC3
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1163617:SCD RS12965
gene id: 1163617:SCD_RS12965
uniprot id: S6B7L0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1163617:SCD RS02630
gene id: 1163617:SCD_RS02630
uniprot id: S6AB69
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163617:SCD RS01640
gene id: 1163617:SCD_RS01640
uniprot id: S6A9I7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

1163617:SCD RS14990
gene id: 1163617:SCD_RS14990
uniprot id: S6B929
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

1163617:SCD RS00975
gene id: 1163617:SCD_RS00975
uniprot id: S6AE79
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

1163617:SCD RS02795
gene id: 1163617:SCD_RS02795
uniprot id: S6A9N3
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

1163617:SCD RS01080
gene id: 1163617:SCD_RS01080
uniprot id: S6AZZ2
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

1163617:SCD RS06200
gene id: 1163617:SCD_RS06200
uniprot id: S6AKE4
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1163617:SCD RS09140
gene id: 1163617:SCD_RS09140
uniprot id: S6ACK6
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163617:SCD RS14405
gene id: 1163617:SCD_RS14405
uniprot id: S6ABF6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1163617:SCD RS03795
gene id: 1163617:SCD_RS03795
uniprot id: S6AFE7
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

1163617:SCD RS09690
gene id: 1163617:SCD_RS09690
uniprot id: S6AM22
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

1163617:SCD RS03645
gene id: 1163617:SCD_RS03645
uniprot id: S6AFB9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1163617:SCD RS02905
gene id: 1163617:SCD_RS02905
uniprot id: S6B155
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1163617:SCD RS13415
gene id: 1163617:SCD_RS13415
uniprot id: S6B7V3
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS07340
gene id: 1163617:SCD_RS07340
uniprot id: S6AA62
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1163617:SCD RS07765
gene id: 1163617:SCD_RS07765
uniprot id: S6AL64
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1163617:SCD RS12480
gene id: 1163617:SCD_RS12480
uniprot id: S6AJ64
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

1163617:SCD RS01585
gene id: 1163617:SCD_RS01585
uniprot id: S6AI10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1163617:SCD RS07970
gene id: 1163617:SCD_RS07970
uniprot id: S6AH47
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1163617:SCD RS13310
gene id: 1163617:SCD_RS13310
uniprot id: S6AJH1
names: Similarity
messages: Belongs to the thioredoxin family.

1163617:SCD RS00170
gene id: 1163617:SCD_RS00170
uniprot id: S6AZD9
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS11675
gene id: 1163617:SCD_RS11675
uniprot id: S6AD49
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163617:SCD RS09480
gene id: 1163617:SCD_RS09480
uniprot id: S6B5B8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1163617:SCD RS14950
gene id: 1163617:SCD_RS14950
uniprot id: S6APH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1163617:SCD RS05120
gene id: 1163617:SCD_RS05120
uniprot id: S6ABN8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1163617:SCD RS05980
gene id: 1163617:SCD_RS05980
uniprot id: S6AGB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TamA family.
messages: Cell outer membrane
messages: Membrane

1163617:SCD RS08055
gene id: 1163617:SCD_RS08055
uniprot id: S6ACC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1163617:SCD RS08945
gene id: 1163617:SCD_RS08945
uniprot id: S6ACJ0
names: Similarity
messages: Belongs to the YfgM family.

1163617:SCD RS00590
gene id: 1163617:SCD_RS00590
uniprot id: S6AHI7
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1163617:SCD RS13890
gene id: 1163617:SCD_RS13890
uniprot id: S6B874
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1163617:SCD RS04400
gene id: 1163617:SCD_RS04400
uniprot id: S6AFR0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1163617:SCD RS05090
gene id: 1163617:SCD_RS05090
uniprot id: S6B2G8
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1163617:SCD RS04450
gene id: 1163617:SCD_RS04450
uniprot id: S6AFR4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1163617:SCD RS01820
gene id: 1163617:SCD_RS01820
uniprot id: S6B0K0
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.

1163617:SCD RS04350
gene id: 1163617:SCD_RS04350
uniprot id: S6AFP9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163617:SCD RS07375
gene id: 1163617:SCD_RS07375
uniprot id: S6B3U9
names: Similarity
messages: Belongs to the PrpD family.

1163617:SCD RS02520
gene id: 1163617:SCD_RS02520
uniprot id: S6AEW0
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1163617:SCD RS09370
gene id: 1163617:SCD_RS09370
uniprot id: S6AAE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1163617:SCD RS06235
gene id: 1163617:SCD_RS06235
uniprot id: S6AGE6
names: Similarity
messages: Belongs to the HesB/IscA family.

1163617:SCD RS15395
gene id: 1163617:SCD_RS15395
uniprot id: S6ABN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1163617:SCD RS13755
gene id: 1163617:SCD_RS13755
uniprot id: S6ANV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

1163617:SCD RS05640
gene id: 1163617:SCD_RS05640
uniprot id: S6ABS7
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

1163617:SCD RS03050
gene id: 1163617:SCD_RS03050
uniprot id: S6AF30
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1163617:SCD RS02030
gene id: 1163617:SCD_RS02030
uniprot id: S6AIC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1163617:SCD RS15295
gene id: 1163617:SCD_RS15295
uniprot id: S6APL9
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1163617:SCD RS14415
gene id: 1163617:SCD_RS14415
uniprot id: S6B8Q0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1163617:SCD RS14120
gene id: 1163617:SCD_RS14120
uniprot id: S6AP30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1163617:SCD RS01980
gene id: 1163617:SCD_RS01980
uniprot id: S6AB28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1163617:SCD RS12170
gene id: 1163617:SCD_RS12170
uniprot id: S6AN70
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1163617:SCD RS11715
gene id: 1163617:SCD_RS11715
uniprot id: S6AIU0
names: Similarity
messages: Belongs to the TPP enzyme family.

1163617:SCD RS09685
gene id: 1163617:SCD_RS09685
uniprot id: S6ACQ8
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163617:SCD RS08665
gene id: 1163617:SCD_RS08665
uniprot id: S6AAB4
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS10175
gene id: 1163617:SCD_RS10175
uniprot id: S6ACU2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1163617:SCD RS03070
gene id: 1163617:SCD_RS03070
uniprot id: S6A9P3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1163617:SCD RS00955
gene id: 1163617:SCD_RS00955
uniprot id: S6AZW4
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS13765
gene id: 1163617:SCD_RS13765
uniprot id: S6AJN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1163617:SCD RS06090
gene id: 1163617:SCD_RS06090
uniprot id: S6ABW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

1163617:SCD RS01915
gene id: 1163617:SCD_RS01915
uniprot id: S6A9J8
names: Function
names: Similarity
messages: Belongs to the UbiT family.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Likely functions as an accessory factor.

1163617:SCD RS08645
gene id: 1163617:SCD_RS08645
uniprot id: S6AHD6
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS08775
gene id: 1163617:SCD_RS08775
uniprot id: S6AAB8
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1163617:SCD RS10040
gene id: 1163617:SCD_RS10040
uniprot id: S6AI30
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1163617:SCD RS03200
gene id: 1163617:SCD_RS03200
uniprot id: S6AF50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1163617:SCD RS15285
gene id: 1163617:SCD_RS15285
uniprot id: S6B984
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS06095
gene id: 1163617:SCD_RS06095
uniprot id: S6AKC4
names: Subcellular Location Annotation
messages: Cytoplasm

1163617:SCD RS12355
gene id: 1163617:SCD_RS12355
uniprot id: S6AJ52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1163617:SCD RS05170
gene id: 1163617:SCD_RS05170
uniprot id: S6ABP2
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1163617:SCD RS02885
gene id: 1163617:SCD_RS02885
uniprot id: S6AB84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1163617:SCD RS14090
gene id: 1163617:SCD_RS14090
uniprot id: S6ADQ2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1163617:SCD RS00425
gene id: 1163617:SCD_RS00425
uniprot id: S6A9D8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

1163617:SCD RS10720
gene id: 1163617:SCD_RS10720
uniprot id: S6AAJ6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1163617:SCD RS09740
gene id: 1163617:SCD_RS09740
uniprot id: S6AM27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1163617:SCD RS10355
gene id: 1163617:SCD_RS10355
uniprot id: S6AMA0
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1163617:SCD RS15200
gene id: 1163617:SCD_RS15200
uniprot id: S6ABM0
names: Function
names: Similarity
messages: Belongs to the ATPase gamma chain family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1163617:SCD RS09585
gene id: 1163617:SCD_RS09585
uniprot id: S6ACQ1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1163617:SCD RS09120
gene id: 1163617:SCD_RS09120
uniprot id: S6ALT1
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1163617:SCD RS01770
gene id: 1163617:SCD_RS01770
uniprot id: S6B0H2
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS08625
gene id: 1163617:SCD_RS08625
uniprot id: S6B4N8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

1163617:SCD RS15110
gene id: 1163617:SCD_RS15110
uniprot id: S6API9
names: Similarity
messages: Belongs to the YjdM family.

1163617:SCD RS13050
gene id: 1163617:SCD_RS13050
uniprot id: S6ADG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1163617:SCD RS00035
gene id: 1163617:SCD_RS00035
uniprot id: S6ADV8
names: Similarity
messages: Belongs to the Smg family.

1163617:SCD RS03120
gene id: 1163617:SCD_RS03120
uniprot id: S6A9P5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1163617:SCD RS06975
gene id: 1163617:SCD_RS06975
uniprot id: S6AKY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1163617:SCD RS05870
gene id: 1163617:SCD_RS05870
uniprot id: S6AK90
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

1163617:SCD RS13635
gene id: 1163617:SCD_RS13635
uniprot id: S6AJL8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1163617:SCD RS13500
gene id: 1163617:SCD_RS13500
uniprot id: S6ANR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

1163617:SCD RS11400
gene id: 1163617:SCD_RS11400
uniprot id: S6B6I0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1163617:SCD RS10010
gene id: 1163617:SCD_RS10010
uniprot id: S6AAG8
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS08245
gene id: 1163617:SCD_RS08245
uniprot id: S6B4E4
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163617:SCD RS10455
gene id: 1163617:SCD_RS10455
uniprot id: S6ACW2
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

1163617:SCD RS16405
gene id: 1163617:SCD_RS16405
uniprot id: S6AA90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1163617:SCD RS09245
gene id: 1163617:SCD_RS09245
uniprot id: S6AAD7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163617:SCD RS14085
gene id: 1163617:SCD_RS14085
uniprot id: S6B8E2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

1163617:SCD RS02620
gene id: 1163617:SCD_RS02620
uniprot id: S6AEX6
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1163617:SCD RS02145
gene id: 1163617:SCD_RS02145
uniprot id: S6A9K7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiU subfamily.
messages: Forms an heterodimer with UbiV.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiV, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

1163617:SCD RS15505
gene id: 1163617:SCD_RS15505
uniprot id: S6A9G5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1163617:SCD RS13800
gene id: 1163617:SCD_RS13800
uniprot id: S6ADM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

1163617:SCD RS08935
gene id: 1163617:SCD_RS08935
uniprot id: S6AHJ0
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1163617:SCD RS06710
gene id: 1163617:SCD_RS06710
uniprot id: S6AA37
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

1163617:SCD RS03835
gene id: 1163617:SCD_RS03835
uniprot id: K6US69
names: Similarity
messages: Belongs to the HypD family.

1163617:SCD RS10960
gene id: 1163617:SCD_RS10960
uniprot id: S6AMI9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1163617:SCD RS11035
gene id: 1163617:SCD_RS11035
uniprot id: S6AMK2
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1163617:SCD RS12995
gene id: 1163617:SCD_RS12995
uniprot id: S6B7L7
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS14465
gene id: 1163617:SCD_RS14465
uniprot id: S6B8T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1163617:SCD RS11570
gene id: 1163617:SCD_RS11570
uniprot id: S6AIR2
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS09415
gene id: 1163617:SCD_RS09415
uniprot id: S6ALY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

1163617:SCD RS14065
gene id: 1163617:SCD_RS14065
uniprot id: S6ADP9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1163617:SCD RS01975
gene id: 1163617:SCD_RS01975
uniprot id: S6B0P1
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

1163617:SCD RS11540
gene id: 1163617:SCD_RS11540
uniprot id: S6AAP7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

1163617:SCD RS00335
gene id: 1163617:SCD_RS00335
uniprot id: S6A9D4
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1163617:SCD RS13750
gene id: 1163617:SCD_RS13750
uniprot id: S6ADM3
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1163617:SCD RS03030
gene id: 1163617:SCD_RS03030
uniprot id: K6V8W5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1163617:SCD RS05725
gene id: 1163617:SCD_RS05725
uniprot id: K6V474
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

1163617:SCD RS02935
gene id: 1163617:SCD_RS02935
uniprot id: S6AB87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1163617:SCD RS13145
gene id: 1163617:SCD_RS13145
uniprot id: S6ADG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1163617:SCD RS09810
gene id: 1163617:SCD_RS09810
uniprot id: S6ACR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1163617:SCD RS01890
gene id: 1163617:SCD_RS01890
uniprot id: S6A9J7
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

1163617:SCD RS02775
gene id: 1163617:SCD_RS02775
uniprot id: S6AEZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane.
messages: Periplasm

1163617:SCD RS12525
gene id: 1163617:SCD_RS12525
uniprot id: S6AAX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1163617:SCD RS00055
gene id: 1163617:SCD_RS00055
uniprot id: S6A9C3
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1163617:SCD RS08220
gene id: 1163617:SCD_RS08220
uniprot id: S6AH76
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1163617:SCD RS12815
gene id: 1163617:SCD_RS12815
uniprot id: S6ADE2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1163617:SCD RS12865
gene id: 1163617:SCD_RS12865
uniprot id: S6B7I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1163617:SCD RS15895
gene id: 1163617:SCD_RS15895
uniprot id: S6ADK0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1163617:SCD RS10810
gene id: 1163617:SCD_RS10810
uniprot id: S6AMG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1163617:SCD RS07380
gene id: 1163617:SCD_RS07380
uniprot id: S6AC65
names: Similarity
messages: Belongs to the citrate synthase family.

1163617:SCD RS07655
gene id: 1163617:SCD_RS07655
uniprot id: S6AC87
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1163617:SCD RS01550
gene id: 1163617:SCD_RS01550
uniprot id: S6B0B0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1163617:SCD RS10265
gene id: 1163617:SCD_RS10265
uniprot id: S6AI57
names: Subcellular Location Annotation
messages: Cell inner membrane

1163617:SCD RS07580
gene id: 1163617:SCD_RS07580
uniprot id: S6AC81
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1163617:SCD RS10710
gene id: 1163617:SCD_RS10710
uniprot id: S6ACX9
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

1163617:SCD RS08105
gene id: 1163617:SCD_RS08105
uniprot id: S6ACC3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1163617:SCD RS09695
gene id: 1163617:SCD_RS09695
uniprot id: S6AAF5
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1163617:SCD RS05815
gene id: 1163617:SCD_RS05815
uniprot id: S6B2V8
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

1163617:SCD RS02020
gene id: 1163617:SCD_RS02020
uniprot id: S6B0P9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1163617:SCD RS01940
gene id: 1163617:SCD_RS01940
uniprot id: S6A9J9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1163617:SCD RS14080
gene id: 1163617:SCD_RS14080
uniprot id: S6AJV2
names: Similarity
messages: Belongs to the pyruvate kinase family.

1163617:SCD RS13760
gene id: 1163617:SCD_RS13760
uniprot id: S6AB82
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1163617:SCD RS03840
gene id: 1163617:SCD_RS03840
uniprot id: S6A9S4
names: Similarity
messages: Belongs to the HypE family.

1163617:SCD RS07290
gene id: 1163617:SCD_RS07290
uniprot id: S6AA60
names: Similarity
messages: Belongs to the BolA/IbaG family.

1163617:SCD RS08455
gene id: 1163617:SCD_RS08455
uniprot id: S6ACF1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163617:SCD RS15155
gene id: 1163617:SCD_RS15155
uniprot id: S6AKC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1163617:SCD RS15235
gene id: 1163617:SCD_RS15235
uniprot id: S6B970
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.

1163617:SCD RS08335
gene id: 1163617:SCD_RS08335
uniprot id: S6AH91
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1163617:SCD RS06575
gene id: 1163617:SCD_RS06575
uniprot id: S6B3C7
names: Similarity
messages: Belongs to the GSP N family.

1163617:SCD RS09145
gene id: 1163617:SCD_RS09145
uniprot id: S6ALT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1163617:SCD RS06025
gene id: 1163617:SCD_RS06025
uniprot id: S6AA10
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1163617:SCD RS09515
gene id: 1163617:SCD_RS09515
uniprot id: S6AM04
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

1163617:SCD RS12255
gene id: 1163617:SCD_RS12255
uniprot id: S6AJ39
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163617:SCD RS09250
gene id: 1163617:SCD_RS09250
uniprot id: S6AHQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1163617:SCD RS14450
gene id: 1163617:SCD_RS14450
uniprot id: S6APA5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

1163617:SCD RS07495
gene id: 1163617:SCD_RS07495
uniprot id: S6AA68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane

1163617:SCD RS12635
gene id: 1163617:SCD_RS12635
uniprot id: S6B7D8
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1163617:SCD RS09375
gene id: 1163617:SCD_RS09375
uniprot id: S6AHS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1163617:SCD RS08915
gene id: 1163617:SCD_RS08915
uniprot id: S6B4W2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1163617:SCD RS10325
gene id: 1163617:SCD_RS10325
uniprot id: S6ACV3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1163617:SCD RS00380
gene id: 1163617:SCD_RS00380
uniprot id: S6A9D6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1163617:SCD RS04485
gene id: 1163617:SCD_RS04485
uniprot id: S6ABJ0
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1163617:SCD RS10145
gene id: 1163617:SCD_RS10145
uniprot id: S6B5P5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1163617:SCD RS06930
gene id: 1163617:SCD_RS06930
uniprot id: S6AA46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1163617:SCD RS03080
gene id: 1163617:SCD_RS03080
uniprot id: S6B188
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1163617:SCD RS04005
gene id: 1163617:SCD_RS04005
uniprot id: S6B1U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1163617:SCD RS12160
gene id: 1163617:SCD_RS12160
uniprot id: S6B743
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1163617:SCD RS13460
gene id: 1163617:SCD_RS13460
uniprot id: S6AJJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

1163617:SCD RS07895
gene id: 1163617:SCD_RS07895
uniprot id: S6AH38
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163617:SCD RS15040
gene id: 1163617:SCD_RS15040
uniprot id: S6AKB8
names: Similarity
messages: Belongs to the peptidase S24 family.

1163617:SCD RS14270
gene id: 1163617:SCD_RS14270
uniprot id: S6AP64
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1163617:SCD RS10390
gene id: 1163617:SCD_RS10390
uniprot id: S6AI69
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1163617:SCD RS04570
gene id: 1163617:SCD_RS04570
uniprot id: S6A9V3
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163617:SCD RS06190
gene id: 1163617:SCD_RS06190
uniprot id: S6B352
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1163617:SCD RS13010
gene id: 1163617:SCD_RS13010
uniprot id: S6AB07
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1163617:SCD RS14765
gene id: 1163617:SCD_RS14765
uniprot id: S6B8Y4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1163617:SCD RS06270
gene id: 1163617:SCD_RS06270
uniprot id: S6ABX7
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

1163617:SCD RS07610
gene id: 1163617:SCD_RS07610
uniprot id: S6AL49
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1163617:SCD RS03370
gene id: 1163617:SCD_RS03370
uniprot id: S6AIZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1163617:SCD RS04905
gene id: 1163617:SCD_RS04905
uniprot id: S6A9W7
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1163617:SCD RS13980
gene id: 1163617:SCD_RS13980
uniprot id: S6AJT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1163617:SCD RS03970
gene id: 1163617:SCD_RS03970
uniprot id: S6A9S9
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1163617:SCD RS00365
gene id: 1163617:SCD_RS00365
uniprot id: S6AZI4
names: Similarity
messages: Belongs to the GSP E family.

1163617:SCD RS02425
gene id: 1163617:SCD_RS02425
uniprot id: S6B0X2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1163617:SCD RS15530
gene id: 1163617:SCD_RS15530
uniprot id: S6A9J3
names: Similarity
messages: Belongs to the isochorismate synthase family.

1163617:SCD RS02945
gene id: 1163617:SCD_RS02945
uniprot id: S6A9N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1163617:SCD RS08195
gene id: 1163617:SCD_RS08195
uniprot id: S6AH73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1163617:SCD RS04200
gene id: 1163617:SCD_RS04200
uniprot id: S6B1Z9
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

1163617:SCD RS10900
gene id: 1163617:SCD_RS10900
uniprot id: S6ACZ3
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1163617:SCD RS10610
gene id: 1163617:SCD_RS10610
uniprot id: S6B601
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS15045
gene id: 1163617:SCD_RS15045
uniprot id: S6B939
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1163617:SCD RS07040
gene id: 1163617:SCD_RS07040
uniprot id: S6AA50
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1163617:SCD RS12470
gene id: 1163617:SCD_RS12470
uniprot id: S6ANA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1163617:SCD RS05465
gene id: 1163617:SCD_RS05465
uniprot id: S6AK23
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS06685
gene id: 1163617:SCD_RS06685
uniprot id: S6AA36
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1163617:SCD RS02505
gene id: 1163617:SCD_RS02505
uniprot id: S6AB61
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS05875
gene id: 1163617:SCD_RS05875
uniprot id: S6AA04
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163617:SCD RS08995
gene id: 1163617:SCD_RS08995
uniprot id: S6ACJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1163617:SCD RS08375
gene id: 1163617:SCD_RS08375
uniprot id: S6ALE9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1163617:SCD RS07090
gene id: 1163617:SCD_RS07090
uniprot id: S6AA52
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS05645
gene id: 1163617:SCD_RS05645
uniprot id: S6AK47
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1163617:SCD RS04245
gene id: 1163617:SCD_RS04245
uniprot id: S6AFM6
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1163617:SCD RS08205
gene id: 1163617:SCD_RS08205
uniprot id: S6ACD0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1163617:SCD RS08160
gene id: 1163617:SCD_RS08160
uniprot id: S6ALB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1163617:SCD RS03215
gene id: 1163617:SCD_RS03215
uniprot id: S6AIX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1163617:SCD RS11415
gene id: 1163617:SCD_RS11415
uniprot id: S6AAN6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1163617:SCD RS00225
gene id: 1163617:SCD_RS00225
uniprot id: S6AAN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1163617:SCD RS01540
gene id: 1163617:SCD_RS01540
uniprot id: S6A9I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

1163617:SCD RS04735
gene id: 1163617:SCD_RS04735
uniprot id: S6B2A9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1163617:SCD RS05560
gene id: 1163617:SCD_RS05560
uniprot id: S6AG54
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

1163617:SCD RS12310
gene id: 1163617:SCD_RS12310
uniprot id: S6B778
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163617:SCD RS02895
gene id: 1163617:SCD_RS02895
uniprot id: S6A9N7
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

1163617:SCD RS15390
gene id: 1163617:SCD_RS15390
uniprot id: S6AE37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1163617:SCD RS11905
gene id: 1163617:SCD_RS11905
uniprot id: S6B6W8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SoxA family.
messages: Binds 2 heme groups per subunit.
messages: Heterodimer of SoxA and SoxX.
messages: Periplasm

1163617:SCD RS09915
gene id: 1163617:SCD_RS09915
uniprot id: S6AM45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1163617:SCD RS15230
gene id: 1163617:SCD_RS15230
uniprot id: S6AKE1
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS09175
gene id: 1163617:SCD_RS09175
uniprot id: S6AAD4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1163617:SCD RS10330
gene id: 1163617:SCD_RS10330
uniprot id: S6AM96
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1163617:SCD RS05595
gene id: 1163617:SCD_RS05595
uniprot id: S6ABS3
names: Similarity
messages: Belongs to the threonine synthase family.

1163617:SCD RS13165
gene id: 1163617:SCD_RS13165
uniprot id: S6B7Q3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163617:SCD RS04035
gene id: 1163617:SCD_RS04035
uniprot id: S6ABF4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1163617:SCD RS09755
gene id: 1163617:SCD_RS09755
uniprot id: S6B5H0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1163617:SCD RS15000
gene id: 1163617:SCD_RS15000
uniprot id: S6APH7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1163617:SCD RS06540
gene id: 1163617:SCD_RS06540
uniprot id: S6AA30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

1163617:SCD RS00855
gene id: 1163617:SCD_RS00855
uniprot id: S6AZU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1163617:SCD RS11015
gene id: 1163617:SCD_RS11015
uniprot id: S6AAK8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

1163617:SCD RS00120
gene id: 1163617:SCD_RS00120
uniprot id: S6AZC9
names: Similarity
messages: Belongs to the hemerythrin family.

1163617:SCD RS08355
gene id: 1163617:SCD_RS08355
uniprot id: S6AAA3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1163617:SCD RS08310
gene id: 1163617:SCD_RS08310
uniprot id: S6AAA1
names: Similarity
messages: Belongs to the asparagine synthetase family.

1163617:SCD RS00200
gene id: 1163617:SCD_RS00200
uniprot id: S6AAM8
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

1163617:SCD RS04515
gene id: 1163617:SCD_RS04515
uniprot id: S6AJP5
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1163617:SCD RS14280
gene id: 1163617:SCD_RS14280
uniprot id: S6AJZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1163617:SCD RS09235
gene id: 1163617:SCD_RS09235
uniprot id: S6ACL1
names: Similarity
messages: Belongs to the UPF0173 family.

1163617:SCD RS08115
gene id: 1163617:SCD_RS08115
uniprot id: S6AA93
names: Similarity
messages: Belongs to the group II decarboxylase family.

1163617:SCD RS08890
gene id: 1163617:SCD_RS08890
uniprot id: S6B4V6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1163617:SCD RS00310
gene id: 1163617:SCD_RS00310
uniprot id: S6A9D3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1163617:SCD RS15220
gene id: 1163617:SCD_RS15220
uniprot id: S6APK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1163617:SCD RS03345
gene id: 1163617:SCD_RS03345
uniprot id: S6AIZ3
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1163617:SCD RS03135
gene id: 1163617:SCD_RS03135
uniprot id: S6AB98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1163617:SCD RS11255
gene id: 1163617:SCD_RS11255
uniprot id: S6B6F0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1163617:SCD RS03800
gene id: 1163617:SCD_RS03800
uniprot id: S6B1Q9
names: Similarity
messages: Belongs to the peptidase A31 family.

1163617:SCD RS09785
gene id: 1163617:SCD_RS09785
uniprot id: S6ACR5
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1163617:SCD RS06135
gene id: 1163617:SCD_RS06135
uniprot id: S6B338
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1163617:SCD RS04240
gene id: 1163617:SCD_RS04240
uniprot id: S6A9U0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1163617:SCD RS13475
gene id: 1163617:SCD_RS13475
uniprot id: S6ANR1
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1163617:SCD RS13065
gene id: 1163617:SCD_RS13065
uniprot id: S6AJD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

1163617:SCD RS02485
gene id: 1163617:SCD_RS02485
uniprot id: S6AIJ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

1163617:SCD RS02675
gene id: 1163617:SCD_RS02675
uniprot id: S6AEY3
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS07885
gene id: 1163617:SCD_RS07885
uniprot id: S6AL75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1163617:SCD RS06300
gene id: 1163617:SCD_RS06300
uniprot id: S6AKG7
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

1163617:SCD RS01580
gene id: 1163617:SCD_RS01580
uniprot id: S6AAZ2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1163617:SCD RS04695
gene id: 1163617:SCD_RS04695
uniprot id: S6AJR4
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1163617:SCD RS10420
gene id: 1163617:SCD_RS10420
uniprot id: S6AI71
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1163617:SCD RS14550
gene id: 1163617:SCD_RS14550
uniprot id: S6APC4
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

1163617:SCD RS02565
gene id: 1163617:SCD_RS02565
uniprot id: S6A9M4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1163617:SCD RS07740
gene id: 1163617:SCD_RS07740
uniprot id: S6AL61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

1163617:SCD RS00400
gene id: 1163617:SCD_RS00400
uniprot id: S6A9D7
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1163617:SCD RS02575
gene id: 1163617:SCD_RS02575
uniprot id: S6B0Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1163617:SCD RS10670
gene id: 1163617:SCD_RS10670
uniprot id: S6AME2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1163617:SCD RS04395
gene id: 1163617:SCD_RS04395
uniprot id: S6A9U6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1163617:SCD RS13865
gene id: 1163617:SCD_RS13865
uniprot id: S6AJQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1163617:SCD RS13375
gene id: 1163617:SCD_RS13375
uniprot id: S6ANP4
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1163617:SCD RS01930
gene id: 1163617:SCD_RS01930
uniprot id: S6AB25
names: Similarity
messages: Belongs to the GppA/Ppx family.

1163617:SCD RS05970
gene id: 1163617:SCD_RS05970
uniprot id: S6AKA6
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS13805
gene id: 1163617:SCD_RS13805
uniprot id: S6ANW2
names: Similarity
messages: Belongs to the CutA family.

1163617:SCD RS03745
gene id: 1163617:SCD_RS03745
uniprot id: S6AFD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1163617:SCD RS01950
gene id: 1163617:SCD_RS01950
uniprot id: S6B0N7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1163617:SCD RS09380
gene id: 1163617:SCD_RS09380
uniprot id: S6B574
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1163617:SCD RS02930
gene id: 1163617:SCD_RS02930
uniprot id: S6B159
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1163617:SCD RS10935
gene id: 1163617:SCD_RS10935
uniprot id: S6AAK5
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1163617:SCD RS00520
gene id: 1163617:SCD_RS00520
uniprot id: S6AHH6
names: Similarity
messages: Belongs to the UPF0250 family.

1163617:SCD RS03385
gene id: 1163617:SCD_RS03385
uniprot id: S6B1E8
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
messages: Homodimer.
messages: In the C-terminal section; belongs to the MurCDEF family.

1163617:SCD RS12340
gene id: 1163617:SCD_RS12340
uniprot id: S6ADA1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

1163617:SCD RS06690
gene id: 1163617:SCD_RS06690
uniprot id: S6AGN1
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS09985
gene id: 1163617:SCD_RS09985
uniprot id: S6AAG7
names: Similarity
messages: Belongs to the universal stress protein A family.

1163617:SCD RS06560
gene id: 1163617:SCD_RS06560
uniprot id: S6AKM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

1163617:SCD RS09795
gene id: 1163617:SCD_RS09795
uniprot id: S6AAF9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1163617:SCD RS12290
gene id: 1163617:SCD_RS12290
uniprot id: S6AD96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

1163617:SCD RS09495
gene id: 1163617:SCD_RS09495
uniprot id: S6AAE7
names: Similarity
messages: Belongs to the SCO1/2 family.

1163617:SCD RS03820
gene id: 1163617:SCD_RS03820
uniprot id: S6AFF2
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

1163617:SCD RS12955
gene id: 1163617:SCD_RS12955
uniprot id: S6AB03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1163617:SCD RS06290
gene id: 1163617:SCD_RS06290
uniprot id: S6B367
names: Similarity
messages: Belongs to the MotB family.

1163617:SCD RS03065
gene id: 1163617:SCD_RS03065
uniprot id: S6AIU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1163617:SCD RS13155
gene id: 1163617:SCD_RS13155
uniprot id: S6AB16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1163617:SCD RS03170
gene id: 1163617:SCD_RS03170
uniprot id: S6A9P7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1163617:SCD RS04885
gene id: 1163617:SCD_RS04885
uniprot id: S6AFW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1163617:SCD RS12975
gene id: 1163617:SCD_RS12975
uniprot id: S6ADF4
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1163617:SCD RS09465
gene id: 1163617:SCD_RS09465
uniprot id: S6ALZ9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1163617:SCD RS00260
gene id: 1163617:SCD_RS00260
uniprot id: S6A9D1
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1163617:SCD RS00230
gene id: 1163617:SCD_RS00230
uniprot id: S6AHD5
names: Similarity
messages: Belongs to the LOG family.

1163617:SCD RS11755
gene id: 1163617:SCD_RS11755
uniprot id: S6AIV1
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1163617:SCD RS08595
gene id: 1163617:SCD_RS08595
uniprot id: S6AHC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1163617:SCD RS13040
gene id: 1163617:SCD_RS13040
uniprot id: S6AJD1
names: Similarity
messages: Belongs to the peptidase M16 family.

1163617:SCD RS10055
gene id: 1163617:SCD_RS10055
uniprot id: S6AM60
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

1163617:SCD RS08700
gene id: 1163617:SCD_RS08700
uniprot id: S6B4Q6
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1163617:SCD RS06935
gene id: 1163617:SCD_RS06935
uniprot id: S6AGT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1163617:SCD RS03110
gene id: 1163617:SCD_RS03110
uniprot id: K6VR48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1163617:SCD RS01320
gene id: 1163617:SCD_RS01320
uniprot id: S6A9H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

1163617:SCD RS14410
gene id: 1163617:SCD_RS14410
uniprot id: S6AK17
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1163617:SCD RS00050
gene id: 1163617:SCD_RS00050
uniprot id: S6AHB0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1163617:SCD RS04250
gene id: 1163617:SCD_RS04250
uniprot id: S6B212
names: Similarity
messages: Belongs to the peptidase M17 family.

1163617:SCD RS02540
gene id: 1163617:SCD_RS02540
uniprot id: S6A9M3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1163617:SCD RS10300
gene id: 1163617:SCD_RS10300
uniprot id: S6ACV2
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

1163617:SCD RS04690
gene id: 1163617:SCD_RS04690
uniprot id: S6ABK4
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1163617:SCD RS04555
gene id: 1163617:SCD_RS04555
uniprot id: S6B280
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1163617:SCD RS02635
gene id: 1163617:SCD_RS02635
uniprot id: S6AIM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1163617:SCD RS10435
gene id: 1163617:SCD_RS10435
uniprot id: S6AMB0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163617:SCD RS04670
gene id: 1163617:SCD_RS04670
uniprot id: S6AJR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1163617:SCD RS08845
gene id: 1163617:SCD_RS08845
uniprot id: S6ACI1
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1163617:SCD RS02380
gene id: 1163617:SCD_RS02380
uniprot id: S6B0W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1163617:SCD RS11645
gene id: 1163617:SCD_RS11645
uniprot id: S6B6N7
names: Subcellular Location Annotation
messages: Cytoplasm

1163617:SCD RS08650
gene id: 1163617:SCD_RS08650
uniprot id: S6B4P4
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS12395
gene id: 1163617:SCD_RS12395
uniprot id: S6AN99
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163617:SCD RS03545
gene id: 1163617:SCD_RS03545
uniprot id: S6AJ27
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163617:SCD RS09115
gene id: 1163617:SCD_RS09115
uniprot id: S6ACK4
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS00815
gene id: 1163617:SCD_RS00815
uniprot id: S6AHL5
names: Similarity
messages: Belongs to the DEAD box helicase family.

1163617:SCD RS03230
gene id: 1163617:SCD_RS03230
uniprot id: S6B1B7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1163617:SCD RS03235
gene id: 1163617:SCD_RS03235
uniprot id: S6ABA4
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1163617:SCD RS04560
gene id: 1163617:SCD_RS04560
uniprot id: S6ABJ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1163617:SCD RS09315
gene id: 1163617:SCD_RS09315
uniprot id: S6ALW5
names: Similarity
messages: Belongs to the HdrA family.

1163617:SCD RS03950
gene id: 1163617:SCD_RS03950
uniprot id: S6AFH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1163617:SCD RS12185
gene id: 1163617:SCD_RS12185
uniprot id: S6B749
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

1163617:SCD RS13530
gene id: 1163617:SCD_RS13530
uniprot id: S6AB56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

1163617:SCD RS13895
gene id: 1163617:SCD_RS13895
uniprot id: S6ADN6
names: Similarity
messages: Belongs to the GSP E family.

1163617:SCD RS04085
gene id: 1163617:SCD_RS04085
uniprot id: S6ABF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1163617:SCD RS07225
gene id: 1163617:SCD_RS07225
uniprot id: S6B3S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1163617:SCD RS10945
gene id: 1163617:SCD_RS10945
uniprot id: S6B682
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1163617:SCD RS10565
gene id: 1163617:SCD_RS10565
uniprot id: S6ACW9
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1163617:SCD RS07370
gene id: 1163617:SCD_RS07370
uniprot id: S6AGY2
names: Similarity
messages: Belongs to the peptidase M18 family.

1163617:SCD RS02725
gene id: 1163617:SCD_RS02725
uniprot id: S6AEZ1
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163617:SCD RS07935
gene id: 1163617:SCD_RS07935
uniprot id: S6AL80
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1163617:SCD RS07620
gene id: 1163617:SCD_RS07620
uniprot id: S6AH10
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1163617:SCD RS14340
gene id: 1163617:SCD_RS14340
uniprot id: S6B8M5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1163617:SCD RS04015
gene id: 1163617:SCD_RS04015
uniprot id: S6AJE2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1163617:SCD RS14585
gene id: 1163617:SCD_RS14585
uniprot id: S6AK61
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

1163617:SCD RS02255
gene id: 1163617:SCD_RS02255
uniprot id: S6AB45
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

1163617:SCD RS04980
gene id: 1163617:SCD_RS04980
uniprot id: S6AJV1
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

1163617:SCD RS05590
gene id: 1163617:SCD_RS05590
uniprot id: S6B2R0
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1163617:SCD RS14805
gene id: 1163617:SCD_RS14805
uniprot id: S6ABI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1163617:SCD RS08770
gene id: 1163617:SCD_RS08770
uniprot id: S6ALL4
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1163617:SCD RS12485
gene id: 1163617:SCD_RS12485
uniprot id: S6B7A9
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

1163617:SCD RS03530
gene id: 1163617:SCD_RS03530
uniprot id: S6AF96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1163617:SCD RS02590
gene id: 1163617:SCD_RS02590
uniprot id: S6A9M5
names: Similarity
messages: Belongs to the GTP cyclohydrolase I family.

1163617:SCD RS13430
gene id: 1163617:SCD_RS13430
uniprot id: S6AB44
names: Similarity
messages: Belongs to the DsrF/TusC family.

1163617:SCD RS10200
gene id: 1163617:SCD_RS10200
uniprot id: S6ACU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

1163617:SCD RS03830
gene id: 1163617:SCD_RS03830
uniprot id: K6V8T9
names: Similarity
messages: Belongs to the HupF/HypC family.

1163617:SCD RS10800
gene id: 1163617:SCD_RS10800
uniprot id: S6B648
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1163617:SCD RS04725
gene id: 1163617:SCD_RS04725
uniprot id: S6A9V9
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS04090
gene id: 1163617:SCD_RS04090
uniprot id: S6AJG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1163617:SCD RS03960
gene id: 1163617:SCD_RS03960
uniprot id: S6ABE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1163617:SCD RS00495
gene id: 1163617:SCD_RS00495
uniprot id: S6AHH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

1163617:SCD RS13875
gene id: 1163617:SCD_RS13875
uniprot id: S6ANX4
names: Similarity
messages: Belongs to the alkaline phosphatase family.

1163617:SCD RS14445
gene id: 1163617:SCD_RS14445
uniprot id: S6ADT8
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1163617:SCD RS06330
gene id: 1163617:SCD_RS06330
uniprot id: S6AA22
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

1163617:SCD RS07965
gene id: 1163617:SCD_RS07965
uniprot id: S6AA87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1163617:SCD RS02660
gene id: 1163617:SCD_RS02660
uniprot id: S6AB71
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1163617:SCD RS03190
gene id: 1163617:SCD_RS03190
uniprot id: S6AIX0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1163617:SCD RS07490
gene id: 1163617:SCD_RS07490
uniprot id: S6AL35
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1163617:SCD RS12015
gene id: 1163617:SCD_RS12015
uniprot id: S6AN52
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163617:SCD RS01605
gene id: 1163617:SCD_RS01605
uniprot id: S6AAZ4
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1163617:SCD RS08365
gene id: 1163617:SCD_RS08365
uniprot id: S6B4H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1163617:SCD RS13830
gene id: 1163617:SCD_RS13830
uniprot id: S6ANW5
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

1163617:SCD RS01925
gene id: 1163617:SCD_RS01925
uniprot id: S6B0N1
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

1163617:SCD RS07320
gene id: 1163617:SCD_RS07320
uniprot id: S6AGX7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163617:SCD RS08465
gene id: 1163617:SCD_RS08465
uniprot id: S6AAA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

1163617:SCD RS11655
gene id: 1163617:SCD_RS11655
uniprot id: S6AMW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1163617:SCD RS11560
gene id: 1163617:SCD_RS11560
uniprot id: S6AMV1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1163617:SCD RS02900
gene id: 1163617:SCD_RS02900
uniprot id: S6AF13
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163617:SCD RS12630
gene id: 1163617:SCD_RS12630
uniprot id: S6AJ82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

1163617:SCD RS14070
gene id: 1163617:SCD_RS14070
uniprot id: S6AP19
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1163617:SCD RS02915
gene id: 1163617:SCD_RS02915
uniprot id: S6AIR3
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1163617:SCD RS02980
gene id: 1163617:SCD_RS02980
uniprot id: S6B174
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1163617:SCD RS13650
gene id: 1163617:SCD_RS13650
uniprot id: S6ANT9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1163617:SCD RS12495
gene id: 1163617:SCD_RS12495
uniprot id: S6ANB2
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1163617:SCD RS13520
gene id: 1163617:SCD_RS13520
uniprot id: S6ADK2
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

1163617:SCD RS08875
gene id: 1163617:SCD_RS08875
uniprot id: S6AAC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

1163617:SCD RS03060
gene id: 1163617:SCD_RS03060
uniprot id: S6AB93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1163617:SCD RS08495
gene id: 1163617:SCD_RS08495
uniprot id: S6AHB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1163617:SCD RS14525
gene id: 1163617:SCD_RS14525
uniprot id: S6APB9
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

1163617:SCD RS01330
gene id: 1163617:SCD_RS01330
uniprot id: S6B049
names: Similarity
messages: Belongs to the P(II) protein family.

1163617:SCD RS10605
gene id: 1163617:SCD_RS10605
uniprot id: S6AI97
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1163617:SCD RS08350
gene id: 1163617:SCD_RS08350
uniprot id: S6ALE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1163617:SCD RS01705
gene id: 1163617:SCD_RS01705
uniprot id: S6AI38
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163617:SCD RS06230
gene id: 1163617:SCD_RS06230
uniprot id: S6AA18
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

1163617:SCD RS02260
gene id: 1163617:SCD_RS02260
uniprot id: S6AIG2
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS00890
gene id: 1163617:SCD_RS00890
uniprot id: S6AHM7
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS13280
gene id: 1163617:SCD_RS13280
uniprot id: S6AB27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1163617:SCD RS15125
gene id: 1163617:SCD_RS15125
uniprot id: S6B953
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1163617:SCD RS05445
gene id: 1163617:SCD_RS05445
uniprot id: S6A9Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1163617:SCD RS04480
gene id: 1163617:SCD_RS04480
uniprot id: S6B270
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1163617:SCD RS13505
gene id: 1163617:SCD_RS13505
uniprot id: S6AB53
names: Similarity
messages: Belongs to the UPF0502 family.

1163617:SCD RS02545
gene id: 1163617:SCD_RS02545
uniprot id: S6AEW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1163617:SCD RS15680
gene id: 1163617:SCD_RS15680
uniprot id: S6AAA4
names: Subcellular Location Annotation
messages: Secreted

1163617:SCD RS08910
gene id: 1163617:SCD_RS08910
uniprot id: S6AHI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1163617:SCD RS10760
gene id: 1163617:SCD_RS10760
uniprot id: S6AMF3
names: Similarity
messages: Belongs to the SUI1 family.

1163617:SCD RS12110
gene id: 1163617:SCD_RS12110
uniprot id: S6B731
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1163617:SCD RS07675
gene id: 1163617:SCD_RS07675
uniprot id: S6B411
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1163617:SCD RS10585
gene id: 1163617:SCD_RS10585
uniprot id: S6B5Z6
names: Caution
names: Function
names: Similarity
messages: Belongs to the Dus family. DusC subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163617:SCD RS15685
gene id: 1163617:SCD_RS15685
uniprot id: S6AH98
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1163617:SCD RS09615
gene id: 1163617:SCD_RS09615
uniprot id: S6AM13
names: Similarity
messages: Belongs to the histone deacetylase family.

1163617:SCD RS03185
gene id: 1163617:SCD_RS03185
uniprot id: S6ABA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1163617:SCD RS06120
gene id: 1163617:SCD_RS06120
uniprot id: S6AKC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

1163617:SCD RS09595
gene id: 1163617:SCD_RS09595
uniprot id: S6AAF1
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1163617:SCD RS07385
gene id: 1163617:SCD_RS07385
uniprot id: S6AL25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

1163617:SCD RS11145
gene id: 1163617:SCD_RS11145
uniprot id: S6AIJ4
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Member of a two-component regulatory system.

1163617:SCD RS09640
gene id: 1163617:SCD_RS09640
uniprot id: S6AM17
names: Similarity
messages: Belongs to the peptidase U62 family.

1163617:SCD RS05070
gene id: 1163617:SCD_RS05070
uniprot id: S6ABN4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163617:SCD RS01600
gene id: 1163617:SCD_RS01600
uniprot id: S6B0C3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1163617:SCD RS07085
gene id: 1163617:SCD_RS07085
uniprot id: S6AKZ3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1163617:SCD RS05500
gene id: 1163617:SCD_RS05500
uniprot id: S6A9Z0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1163617:SCD RS03195
gene id: 1163617:SCD_RS03195
uniprot id: S6A9P8
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1163617:SCD RS16410
gene id: 1163617:SCD_RS16410
uniprot id: S6AAA5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1163617:SCD RS03100
gene id: 1163617:SCD_RS03100
uniprot id: K6V5B5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1163617:SCD RS09430
gene id: 1163617:SCD_RS09430
uniprot id: S6B5A1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1163617:SCD RS10460
gene id: 1163617:SCD_RS10460
uniprot id: S6AMB4
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

1163617:SCD RS08870
gene id: 1163617:SCD_RS08870
uniprot id: S6ALN3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1163617:SCD RS03910
gene id: 1163617:SCD_RS03910
uniprot id: S6ABE5
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

1163617:SCD RS03730
gene id: 1163617:SCD_RS03730
uniprot id: S6ABD5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1163617:SCD RS06085
gene id: 1163617:SCD_RS06085
uniprot id: S6B323
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

1163617:SCD RS10550
gene id: 1163617:SCD_RS10550
uniprot id: S6AAI9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1163617:SCD RS00345
gene id: 1163617:SCD_RS00345
uniprot id: S6AZI0
names: Similarity
messages: Belongs to the UPF0235 family.

1163617:SCD RS09150
gene id: 1163617:SCD_RS09150
uniprot id: S6AAD3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1163617:SCD RS02790
gene id: 1163617:SCD_RS02790
uniprot id: S6AIP1
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1163617:SCD RS15005
gene id: 1163617:SCD_RS15005
uniprot id: S6ABK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1163617:SCD RS04990
gene id: 1163617:SCD_RS04990
uniprot id: S6AFX7
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS08305
gene id: 1163617:SCD_RS08305
uniprot id: S6ALD8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

1163617:SCD RS03715
gene id: 1163617:SCD_RS03715
uniprot id: S6A9R9
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1163617:SCD RS05820
gene id: 1163617:SCD_RS05820
uniprot id: S6ABU1
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163617:SCD RS09055
gene id: 1163617:SCD_RS09055
uniprot id: S6AHL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1163617:SCD RS14900
gene id: 1163617:SCD_RS14900
uniprot id: S6APG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1163617:SCD RS03125
gene id: 1163617:SCD_RS03125
uniprot id: S6AF40
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1163617:SCD RS12260
gene id: 1163617:SCD_RS12260
uniprot id: S6B765
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1163617:SCD RS03725
gene id: 1163617:SCD_RS03725
uniprot id: S6B1P0
names: Similarity
messages: Belongs to the UPF0758 family.

1163617:SCD RS04190
gene id: 1163617:SCD_RS04190
uniprot id: S6AJI5
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1163617:SCD RS13060
gene id: 1163617:SCD_RS13060
uniprot id: S6AB11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

1163617:SCD RS02270
gene id: 1163617:SCD_RS02270
uniprot id: S6AES3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1163617:SCD RS08970
gene id: 1163617:SCD_RS08970
uniprot id: S6ACJ3
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

1163617:SCD RS02460
gene id: 1163617:SCD_RS02460
uniprot id: S6AIJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1163617:SCD RS12315
gene id: 1163617:SCD_RS12315
uniprot id: S6AD98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

1163617:SCD RS02320
gene id: 1163617:SCD_RS02320
uniprot id: S6AET0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1163617:SCD RS09580
gene id: 1163617:SCD_RS09580
uniprot id: S6B5D6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1163617:SCD RS13170
gene id: 1163617:SCD_RS13170
uniprot id: S6ADH1
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

1163617:SCD RS00610
gene id: 1163617:SCD_RS00610
uniprot id: S6AAQ9
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1163617:SCD RS03455
gene id: 1163617:SCD_RS03455
uniprot id: S6AF83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1163617:SCD RS00475
gene id: 1163617:SCD_RS00475
uniprot id: S6A9E0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1163617:SCD RS03420
gene id: 1163617:SCD_RS03420
uniprot id: S6AJ04
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1163617:SCD RS03085
gene id: 1163617:SCD_RS03085
uniprot id: S6AB95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1163617:SCD RS07235
gene id: 1163617:SCD_RS07235
uniprot id: S6AL09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1163617:SCD RS02140
gene id: 1163617:SCD_RS02140
uniprot id: S6AIE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiV subfamily.
messages: Forms an heterodimer with UbiU.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiU, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

1163617:SCD RS05550
gene id: 1163617:SCD_RS05550
uniprot id: S6AK32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

1163617:SCD RS07065
gene id: 1163617:SCD_RS07065
uniprot id: S6AA51
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1163617:SCD RS10540
gene id: 1163617:SCD_RS10540
uniprot id: S6ACW8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1163617:SCD RS09225
gene id: 1163617:SCD_RS09225
uniprot id: S6AHP8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1163617:SCD RS07405
gene id: 1163617:SCD_RS07405
uniprot id: S6AC67
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

1163617:SCD RS01650
gene id: 1163617:SCD_RS01650
uniprot id: S6AAZ9
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

1163617:SCD RS02645
gene id: 1163617:SCD_RS02645
uniprot id: S6AEY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility.
messages: Bacterial flagellum basal body
messages: Belongs to the YcgR family.
messages: Monomer. Interacts with the flagellar basal bodies.

1163617:SCD RS15275
gene id: 1163617:SCD_RS15275
uniprot id: S6ABM7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1163617:SCD RS04180
gene id: 1163617:SCD_RS04180
uniprot id: S6B1Z2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1163617:SCD RS13490
gene id: 1163617:SCD_RS13490
uniprot id: S6B7X0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1163617:SCD RS04860
gene id: 1163617:SCD_RS04860
uniprot id: S6A9W5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

1163617:SCD RS04040
gene id: 1163617:SCD_RS04040
uniprot id: S6AJE8
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS07435
gene id: 1163617:SCD_RS07435
uniprot id: S6AL30
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1163617:SCD RS02465
gene id: 1163617:SCD_RS02465
uniprot id: S6A9M0
names: Similarity
messages: Belongs to the peptidase S13 family.

1163617:SCD RS05950
gene id: 1163617:SCD_RS05950
uniprot id: S6AA07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1163617:SCD RS12300
gene id: 1163617:SCD_RS12300
uniprot id: S6AAW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1163617:SCD RS06390
gene id: 1163617:SCD_RS06390
uniprot id: S6B385
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

1163617:SCD RS03160
gene id: 1163617:SCD_RS03160
uniprot id: S6AB99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1163617:SCD RS14980
gene id: 1163617:SCD_RS14980
uniprot id: S6ABK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1163617:SCD RS11190
gene id: 1163617:SCD_RS11190
uniprot id: S6AAL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1163617:SCD RS12230
gene id: 1163617:SCD_RS12230
uniprot id: S6AJ36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1163617:SCD RS15015
gene id: 1163617:SCD_RS15015
uniprot id: S6B934
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1163617:SCD RS04795
gene id: 1163617:SCD_RS04795
uniprot id: S6AJS5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1163617:SCD RS01880
gene id: 1163617:SCD_RS01880
uniprot id: S6AB21
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

1163617:SCD RS10820
gene id: 1163617:SCD_RS10820
uniprot id: S6AID9
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

1163617:SCD RS08410
gene id: 1163617:SCD_RS08410
uniprot id: S6ALF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1163617:SCD RS07530
gene id: 1163617:SCD_RS07530
uniprot id: S6AC77
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1163617:SCD RS03150
gene id: 1163617:SCD_RS03150
uniprot id: S6AF44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1163617:SCD RS10005
gene id: 1163617:SCD_RS10005
uniprot id: S6AM53
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS11445
gene id: 1163617:SCD_RS11445
uniprot id: S6AIP2
names: Similarity
messages: Belongs to the HSP15 family.

1163617:SCD RS05135
gene id: 1163617:SCD_RS05135
uniprot id: S6AFZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

1163617:SCD RS10075
gene id: 1163617:SCD_RS10075
uniprot id: S6ACT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PsiE family.
messages: Cell inner membrane
messages: Membrane

1163617:SCD RS10865
gene id: 1163617:SCD_RS10865
uniprot id: S6AAK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1163617:SCD RS02835
gene id: 1163617:SCD_RS02835
uniprot id: S6AB81
names: Similarity
messages: Belongs to the GSP E family.

1163617:SCD RS07195
gene id: 1163617:SCD_RS07195
uniprot id: S6AGW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1163617:SCD RS12020
gene id: 1163617:SCD_RS12020
uniprot id: S6AAU4
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1163617:SCD RS07295
gene id: 1163617:SCD_RS07295
uniprot id: S6AGX4
names: Similarity
messages: Belongs to the YciI family.

1163617:SCD RS00350
gene id: 1163617:SCD_RS00350
uniprot id: S6AAN9
names: Similarity
messages: Belongs to the YggT family.

1163617:SCD RS13390
gene id: 1163617:SCD_RS13390
uniprot id: S6B7U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1163617:SCD RS07325
gene id: 1163617:SCD_RS07325
uniprot id: S6B3U1
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1163617:SCD RS04215
gene id: 1163617:SCD_RS04215
uniprot id: S6A9T9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1163617:SCD RS06980
gene id: 1163617:SCD_RS06980
uniprot id: S6AA48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1163617:SCD RS09325
gene id: 1163617:SCD_RS09325
uniprot id: S6AHR8
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1163617:SCD RS10560
gene id: 1163617:SCD_RS10560
uniprot id: S6B5Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

1163617:SCD RS03320
gene id: 1163617:SCD_RS03320
uniprot id: S6AIZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsB sub-subfamily.
messages: Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane

1163617:SCD RS08990
gene id: 1163617:SCD_RS08990
uniprot id: S6B4Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1163617:SCD RS10125
gene id: 1163617:SCD_RS10125
uniprot id: S6ACT8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1163617:SCD RS12215
gene id: 1163617:SCD_RS12215
uniprot id: S6AD88
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1163617:SCD RS06920
gene id: 1163617:SCD_RS06920
uniprot id: S6AC34
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1163617:SCD RS10105
gene id: 1163617:SCD_RS10105
uniprot id: S6AM66
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1163617:SCD RS12195
gene id: 1163617:SCD_RS12195
uniprot id: S6AN73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

1163617:SCD RS05515
gene id: 1163617:SCD_RS05515
uniprot id: S6ABR7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1163617:SCD RS12330
gene id: 1163617:SCD_RS12330
uniprot id: S6AJ49
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1163617:SCD RS14790
gene id: 1163617:SCD_RS14790
uniprot id: S6B8Y8
names: Similarity
messages: Belongs to the asparagine synthetase family.

1163617:SCD RS09745
gene id: 1163617:SCD_RS09745
uniprot id: S6AAF7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1163617:SCD RS09575
gene id: 1163617:SCD_RS09575
uniprot id: S6AHX0
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1163617:SCD RS14770
gene id: 1163617:SCD_RS14770
uniprot id: S6ADW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1163617:SCD RS14640
gene id: 1163617:SCD_RS14640
uniprot id: S6B8W0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1163617:SCD RS12295
gene id: 1163617:SCD_RS12295
uniprot id: S6AN85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1163617:SCD RS12705
gene id: 1163617:SCD_RS12705
uniprot id: S6AJ90
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1163617:SCD RS14130
gene id: 1163617:SCD_RS14130
uniprot id: S6AJW4
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1163617:SCD RS06280
gene id: 1163617:SCD_RS06280
uniprot id: S6AA20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

1163617:SCD RS10980
gene id: 1163617:SCD_RS10980
uniprot id: S6ACZ8
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1163617:SCD RS15135
gene id: 1163617:SCD_RS15135
uniprot id: S6AE08
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163617:SCD RS02745
gene id: 1163617:SCD_RS02745
uniprot id: S6A9N1
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

1163617:SCD RS12490
gene id: 1163617:SCD_RS12490
uniprot id: S6ADB3
names: Similarity
messages: Belongs to the YoeB family.

1163617:SCD RS15595
gene id: 1163617:SCD_RS15595
uniprot id: S6B2B3
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1163617:SCD RS03365
gene id: 1163617:SCD_RS03365
uniprot id: S6ABB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1163617:SCD RS14575
gene id: 1163617:SCD_RS14575
uniprot id: S6APC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane

1163617:SCD RS12810
gene id: 1163617:SCD_RS12810
uniprot id: S6B7H4
names: Similarity
messages: Belongs to the PhoH family.

1163617:SCD RS05790
gene id: 1163617:SCD_RS05790
uniprot id: S6B2V2
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

1163617:SCD RS14745
gene id: 1163617:SCD_RS14745
uniprot id: S6ADW7
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1163617:SCD RS07120
gene id: 1163617:SCD_RS07120
uniprot id: S6AGV5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1163617:SCD RS02890
gene id: 1163617:SCD_RS02890
uniprot id: S6AIQ9
names: Similarity
messages: Belongs to the BolA/IbaG family.

1163617:SCD RS10600
gene id: 1163617:SCD_RS10600
uniprot id: S6AAJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1163617:SCD RS00725
gene id: 1163617:SCD_RS00725
uniprot id: S6AE46
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1163617:SCD RS16400
gene id: 1163617:SCD_RS16400
uniprot id: S6AL94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1163617:SCD RS08540
gene id: 1163617:SCD_RS08540
uniprot id: S6AAA9
names: Similarity
messages: Belongs to the sulfate adenylyltransferase family.

1163617:SCD RS08255
gene id: 1163617:SCD_RS08255
uniprot id: S6ALD0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1163617:SCD RS02470
gene id: 1163617:SCD_RS02470
uniprot id: S6AEV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

1163617:SCD RS05125
gene id: 1163617:SCD_RS05125
uniprot id: S6AJX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1163617:SCD RS03140
gene id: 1163617:SCD_RS03140
uniprot id: S6AIV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1163617:SCD RS10225
gene id: 1163617:SCD_RS10225
uniprot id: S6ACU6
names: Similarity
messages: Belongs to the barstar family.

1163617:SCD RS06885
gene id: 1163617:SCD_RS06885
uniprot id: S6AGS4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1163617:SCD RS01790
gene id: 1163617:SCD_RS01790
uniprot id: S6AEK7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

1163617:SCD RS14975
gene id: 1163617:SCD_RS14975
uniprot id: S6APH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1163617:SCD RS08075
gene id: 1163617:SCD_RS08075
uniprot id: S6B4A6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1163617:SCD RS04520
gene id: 1163617:SCD_RS04520
uniprot id: S6A9V1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163617:SCD RS14490
gene id: 1163617:SCD_RS14490
uniprot id: S6B8T4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1163617:SCD RS13840
gene id: 1163617:SCD_RS13840
uniprot id: S6AJQ0
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

1163617:SCD RS04365
gene id: 1163617:SCD_RS04365
uniprot id: S6AJM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbiQ family.
messages: Membrane

1163617:SCD RS12305
gene id: 1163617:SCD_RS12305
uniprot id: S6AJ46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1163617:SCD RS10815
gene id: 1163617:SCD_RS10815
uniprot id: S6AAK0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1163617:SCD RS07660
gene id: 1163617:SCD_RS07660
uniprot id: S6AL54
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

1163617:SCD RS12150
gene id: 1163617:SCD_RS12150
uniprot id: S6AAV2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1163617:SCD RS08630
gene id: 1163617:SCD_RS08630
uniprot id: S6ACG4
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1163617:SCD RS08705
gene id: 1163617:SCD_RS08705
uniprot id: S6ACH0
names: Similarity
messages: Belongs to the MEMO1 family.

1163617:SCD RS07980
gene id: 1163617:SCD_RS07980
uniprot id: S6ACB4
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163617:SCD RS10085
gene id: 1163617:SCD_RS10085
uniprot id: S6AAH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

1163617:SCD RS14495
gene id: 1163617:SCD_RS14495
uniprot id: S6ADU5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1163617:SCD RS11565
gene id: 1163617:SCD_RS11565
uniprot id: S6AAP9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1163617:SCD RS07150
gene id: 1163617:SCD_RS07150
uniprot id: S6B3R1
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS00115
gene id: 1163617:SCD_RS00115
uniprot id: S6ADW8
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS04575
gene id: 1163617:SCD_RS04575
uniprot id: S6AFS8
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1163617:SCD RS03165
gene id: 1163617:SCD_RS03165
uniprot id: S6AIW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1163617:SCD RS08435
gene id: 1163617:SCD_RS08435
uniprot id: S6ALF7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1163617:SCD RS03735
gene id: 1163617:SCD_RS03735
uniprot id: S6AJ61
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1163617:SCD RS04445
gene id: 1163617:SCD_RS04445
uniprot id: S6A9U8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1163617:SCD RS08250
gene id: 1163617:SCD_RS08250
uniprot id: S6ACD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.

1163617:SCD RS02340
gene id: 1163617:SCD_RS02340
uniprot id: S6AIH4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1163617:SCD RS06325
gene id: 1163617:SCD_RS06325
uniprot id: S6AKH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1163617:SCD RS00370
gene id: 1163617:SCD_RS00370
uniprot id: S6AAP1
names: Similarity
messages: Belongs to the GSP E family.

1163617:SCD RS14435
gene id: 1163617:SCD_RS14435
uniprot id: S6AK31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1163617:SCD RS10015
gene id: 1163617:SCD_RS10015
uniprot id: S6AI27
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS04565
gene id: 1163617:SCD_RS04565
uniprot id: S6AJP9
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1163617:SCD RS04660
gene id: 1163617:SCD_RS04660
uniprot id: S6ABK2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1163617:SCD RS07280
gene id: 1163617:SCD_RS07280
uniprot id: S6AC59
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

1163617:SCD RS09815
gene id: 1163617:SCD_RS09815
uniprot id: S6AM35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1163617:SCD RS05940
gene id: 1163617:SCD_RS05940
uniprot id: S6ABV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

1163617:SCD RS08975
gene id: 1163617:SCD_RS08975
uniprot id: S6ALQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1163617:SCD RS12460
gene id: 1163617:SCD_RS12460
uniprot id: S6B7A4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1163617:SCD RS12115
gene id: 1163617:SCD_RS12115
uniprot id: S6AD80
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1163617:SCD RS12325
gene id: 1163617:SCD_RS12325
uniprot id: S6AAW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1163617:SCD RS00270
gene id: 1163617:SCD_RS00270
uniprot id: S6AZG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1163617:SCD RS12200
gene id: 1163617:SCD_RS12200
uniprot id: S6AAV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1163617:SCD RS02955
gene id: 1163617:SCD_RS02955
uniprot id: S6B165
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1163617:SCD RS07975
gene id: 1163617:SCD_RS07975
uniprot id: S6B482
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1163617:SCD RS08735
gene id: 1163617:SCD_RS08735
uniprot id: S6ALL0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163617:SCD RS11420
gene id: 1163617:SCD_RS11420
uniprot id: S6AIN8
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1163617:SCD RS13780
gene id: 1163617:SCD_RS13780
uniprot id: S6ANV8
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1163617:SCD RS06080
gene id: 1163617:SCD_RS06080
uniprot id: S6AGC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

1163617:SCD RS12680
gene id: 1163617:SCD_RS12680
uniprot id: S6AJ88
names: Similarity
messages: Belongs to the glyoxalase I family.

1163617:SCD RS04730
gene id: 1163617:SCD_RS04730
uniprot id: S6AFU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1163617:SCD RS03655
gene id: 1163617:SCD_RS03655
uniprot id: S6ABD0
names: Similarity
messages: Belongs to the thioredoxin family.

1163617:SCD RS09520
gene id: 1163617:SCD_RS09520
uniprot id: S6AAE8
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

1163617:SCD RS12555
gene id: 1163617:SCD_RS12555
uniprot id: S6AJ72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1163617:SCD RS10970
gene id: 1163617:SCD_RS10970
uniprot id: S6AIG3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1163617:SCD RS03175
gene id: 1163617:SCD_RS03175
uniprot id: S6AF47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1163617:SCD RS10955
gene id: 1163617:SCD_RS10955
uniprot id: S6ACZ7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1163617:SCD RS06355
gene id: 1163617:SCD_RS06355
uniprot id: S6AA23
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1163617:SCD RS01010
gene id: 1163617:SCD_RS01010
uniprot id: S6AAT5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1163617:SCD RS09135
gene id: 1163617:SCD_RS09135
uniprot id: S6B515
names: Similarity
messages: Belongs to the P(II) protein family.

1163617:SCD RS11495
gene id: 1163617:SCD_RS11495
uniprot id: S6AIP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1163617:SCD RS06250
gene id: 1163617:SCD_RS06250
uniprot id: S6AKF6
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1163617:SCD RS00180
gene id: 1163617:SCD_RS00180
uniprot id: S6AHC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

1163617:SCD RS00920
gene id: 1163617:SCD_RS00920
uniprot id: S6A9F8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1163617:SCD RS00420
gene id: 1163617:SCD_RS00420
uniprot id: S6AHG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1163617:SCD RS08070
gene id: 1163617:SCD_RS08070
uniprot id: S6AH59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1163617:SCD RS09525
gene id: 1163617:SCD_RS09525
uniprot id: S6AHW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1163617:SCD RS08440
gene id: 1163617:SCD_RS08440
uniprot id: S6AAA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1163617:SCD RS13385
gene id: 1163617:SCD_RS13385
uniprot id: S6AJI2
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

1163617:SCD RS08425
gene id: 1163617:SCD_RS08425
uniprot id: S6B4J0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1163617:SCD RS13305
gene id: 1163617:SCD_RS13305
uniprot id: S6AB29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1163617:SCD RS15255
gene id: 1163617:SCD_RS15255
uniprot id: S6AKE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

1163617:SCD RS08840
gene id: 1163617:SCD_RS08840
uniprot id: S6B4U1
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1163617:SCD RS11660
gene id: 1163617:SCD_RS11660
uniprot id: S6AAQ8
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1163617:SCD RS14650
gene id: 1163617:SCD_RS14650
uniprot id: S6APD2
names: Similarity
messages: Belongs to the asparagine synthetase family.

1163617:SCD RS14040
gene id: 1163617:SCD_RS14040
uniprot id: S6ADP7
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

1163617:SCD RS09360
gene id: 1163617:SCD_RS09360
uniprot id: S6ACM5
names: Similarity
messages: Belongs to the UPF0434 family.

1163617:SCD RS00155
gene id: 1163617:SCD_RS00155
uniprot id: S6AHC5
names: Similarity
messages: Belongs to the GSP E family.

1163617:SCD RS01630
gene id: 1163617:SCD_RS01630
uniprot id: S6AAZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1163617:SCD RS11055
gene id: 1163617:SCD_RS11055
uniprot id: S6AD04
names: Similarity
messages: Belongs to the UPF0178 family.

1163617:SCD RS05625
gene id: 1163617:SCD_RS05625
uniprot id: S6A9Z5
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1163617:SCD RS03650
gene id: 1163617:SCD_RS03650
uniprot id: S6B1L2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163617:SCD RS00005
gene id: 1163617:SCD_RS00005
uniprot id: S6ADV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1163617:SCD RS06525
gene id: 1163617:SCD_RS06525
uniprot id: S6B3B5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

1163617:SCD RS09020
gene id: 1163617:SCD_RS09020
uniprot id: S6ACJ7
names: Similarity
messages: Belongs to the RecJ family.

1163617:SCD RS08475
gene id: 1163617:SCD_RS08475
uniprot id: S6B4K5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1163617:SCD RS09255
gene id: 1163617:SCD_RS09255
uniprot id: S6B543
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1163617:SCD RS12835
gene id: 1163617:SCD_RS12835
uniprot id: S6AJA4
names: Function
names: Subunit
messages: Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein.
messages: Monomer in both c-di-GMP-bound and free forms.

1163617:SCD RS12945
gene id: 1163617:SCD_RS12945
uniprot id: S6ADF2
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1163617:SCD RS09940
gene id: 1163617:SCD_RS09940
uniprot id: S6AI18
names: Similarity
messages: Belongs to the universal stress protein A family.

1163617:SCD RS09790
gene id: 1163617:SCD_RS09790
uniprot id: S6AM32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1163617:SCD RS06285
gene id: 1163617:SCD_RS06285
uniprot id: S6AGF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1163617:SCD RS04340
gene id: 1163617:SCD_RS04340
uniprot id: S6AJL2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1163617:SCD RS10045
gene id: 1163617:SCD_RS10045
uniprot id: S6B5M5
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO large chain family. Type I subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterohexadecamer of 8 large chains and 8 small chains.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.

1163617:SCD RS14895
gene id: 1163617:SCD_RS14895
uniprot id: S6ADY3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163617:SCD RS09475
gene id: 1163617:SCD_RS09475
uniprot id: S6AHV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1163617:SCD RS00910
gene id: 1163617:SCD_RS00910
uniprot id: S6AAT0
names: Similarity
messages: Belongs to the UPF0111 family.

1163617:SCD RS08430
gene id: 1163617:SCD_RS08430
uniprot id: S6ACE9
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1163617:SCD RS02785
gene id: 1163617:SCD_RS02785
uniprot id: S6AB78
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

1163617:SCD RS09910
gene id: 1163617:SCD_RS09910
uniprot id: S6ACS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1163617:SCD RS10535
gene id: 1163617:SCD_RS10535
uniprot id: S6B5Y4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1163617:SCD RS03095
gene id: 1163617:SCD_RS03095
uniprot id: K6V8W5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1163617:SCD RS00250
gene id: 1163617:SCD_RS00250
uniprot id: S6AAN2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1163617:SCD RS13180
gene id: 1163617:SCD_RS13180
uniprot id: S6AB18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

1163617:SCD RS04655
gene id: 1163617:SCD_RS04655
uniprot id: S6B296
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1163617:SCD RS05065
gene id: 1163617:SCD_RS05065
uniprot id: S6B2G5
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

1163617:SCD RS12670
gene id: 1163617:SCD_RS12670
uniprot id: S6AND8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1163617:SCD RS06045
gene id: 1163617:SCD_RS06045
uniprot id: S6AKB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

1163617:SCD RS00415
gene id: 1163617:SCD_RS00415
uniprot id: S6AAP4
names: Subcellular Location Annotation
messages: Cytoplasm

1163617:SCD RS13545
gene id: 1163617:SCD_RS13545
uniprot id: S6ADK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1163617:SCD RS13535
gene id: 1163617:SCD_RS13535
uniprot id: S6AJK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

1163617:SCD RS13160
gene id: 1163617:SCD_RS13160
uniprot id: S6AJE7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1163617:SCD RS00450
gene id: 1163617:SCD_RS00450
uniprot id: S6A9D9
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1163617:SCD RS16415
gene id: 1163617:SCD_RS16415
uniprot id: S6AHA0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of five rings (E,L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1163617:SCD RS13380
gene id: 1163617:SCD_RS13380
uniprot id: S6AB38
names: Similarity
messages: Belongs to the HesB/IscA family.

1163617:SCD RS02750
gene id: 1163617:SCD_RS02750
uniprot id: S6AEZ5
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

1163617:SCD RS02960
gene id: 1163617:SCD_RS02960
uniprot id: S6AB89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1163617:SCD RS11615
gene id: 1163617:SCD_RS11615
uniprot id: S6AIS1
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

1163617:SCD RS13510
gene id: 1163617:SCD_RS13510
uniprot id: S6AJK0
names: Caution
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1163617:SCD RS14035
gene id: 1163617:SCD_RS14035
uniprot id: S6B8C3
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1163617:SCD RS06010
gene id: 1163617:SCD_RS06010
uniprot id: S6B301
names: Similarity
messages: Belongs to the MlaA family.

1163617:SCD RS04635
gene id: 1163617:SCD_RS04635
uniprot id: S6ABK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1163617:SCD RS03225
gene id: 1163617:SCD_RS03225
uniprot id: S6AF53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1163617:SCD RS03445
gene id: 1163617:SCD_RS03445
uniprot id: S6AJ09
names: Function
names: Similarity
messages: Belongs to the ATPase gamma chain family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1163617:SCD RS04510
gene id: 1163617:SCD_RS04510
uniprot id: K6VQA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1163617:SCD RS00735
gene id: 1163617:SCD_RS00735
uniprot id: S6AAR7
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1163617:SCD RS15210
gene id: 1163617:SCD_RS15210
uniprot id: S6B966
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1163617:SCD RS00715
gene id: 1163617:SCD_RS00715
uniprot id: S6AHK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1163617:SCD RS06590
gene id: 1163617:SCD_RS06590
uniprot id: S6AA32
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS06915
gene id: 1163617:SCD_RS06915
uniprot id: S6B3M7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1163617:SCD RS07480
gene id: 1163617:SCD_RS07480
uniprot id: S6B3W5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1163617:SCD RS00175
gene id: 1163617:SCD_RS00175
uniprot id: S6AAM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

1163617:SCD RS13950
gene id: 1163617:SCD_RS13950
uniprot id: S6ABA5
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1163617:SCD RS02860
gene id: 1163617:SCD_RS02860
uniprot id: S6AB83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane

1163617:SCD RS14940
gene id: 1163617:SCD_RS14940
uniprot id: S6B918
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

1163617:SCD RS06615
gene id: 1163617:SCD_RS06615
uniprot id: S6AGL7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1163617:SCD RS15490
gene id: 1163617:SCD_RS15490
uniprot id: S6AE36
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1163617:SCD RS11180
gene id: 1163617:SCD_RS11180
uniprot id: S6AD13
names: Similarity
messages: Belongs to the CmpA/NrtA family.

1163617:SCD RS12665
gene id: 1163617:SCD_RS12665
uniprot id: S6ADC8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

1163617:SCD RS07605
gene id: 1163617:SCD_RS07605
uniprot id: S6AC84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1163617:SCD RS04710
gene id: 1163617:SCD_RS04710
uniprot id: S6B2A4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1163617:SCD RS04620
gene id: 1163617:SCD_RS04620
uniprot id: S6A9V5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1163617:SCD RS09830
gene id: 1163617:SCD_RS09830
uniprot id: S6B5I3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1163617:SCD RS08240
gene id: 1163617:SCD_RS08240
uniprot id: S6AH79
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1163617:SCD RS08955
gene id: 1163617:SCD_RS08955
uniprot id: S6AAC5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1163617:SCD RS04490
gene id: 1163617:SCD_RS04490
uniprot id: S6AJP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1163617:SCD RS06530
gene id: 1163617:SCD_RS06530
uniprot id: S6ABZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1163617:SCD RS05080
gene id: 1163617:SCD_RS05080
uniprot id: S6A9X4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1163617:SCD RS09775
gene id: 1163617:SCD_RS09775
uniprot id: S6AHZ5
names: Similarity
messages: Belongs to the bacterial secretin family.

1163617:SCD RS08950
gene id: 1163617:SCD_RS08950
uniprot id: S6ALP8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1163617:SCD RS09770
gene id: 1163617:SCD_RS09770
uniprot id: S6AAF8
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

1163617:SCD RS06220
gene id: 1163617:SCD_RS06220
uniprot id: S6ABX2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

1163617:SCD RS05205
gene id: 1163617:SCD_RS05205
uniprot id: S6A9X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1163617:SCD RS09805
gene id: 1163617:SCD_RS09805
uniprot id: S6B5I0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1163617:SCD RS03465
gene id: 1163617:SCD_RS03465
uniprot id: S6ABB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1163617:SCD RS14390
gene id: 1163617:SCD_RS14390
uniprot id: S6B8P2
names: Subcellular Location Annotation
messages: Membrane

1163617:SCD RS09400
gene id: 1163617:SCD_RS09400
uniprot id: S6AHT3
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1163617:SCD RS00295
gene id: 1163617:SCD_RS00295
uniprot id: S6AZG9
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1163617:SCD RS01050
gene id: 1163617:SCD_RS01050
uniprot id: S6AE90
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.