1159554:AFK67 RS05170
gene id: 1159554:AFK67_RS05170
uniprot id: A0A0K2NZE4
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS18050
gene id: 1159554:AFK67_RS18050
uniprot id: A0A0K2P6B0
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1159554:AFK67 RS20260
gene id: 1159554:AFK67_RS20260
uniprot id: A0A0K2P7D2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

1159554:AFK67 RS15270
gene id: 1159554:AFK67_RS15270
uniprot id: A0A0K2P5G9
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: Binds 1 FAD per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Consists of two distinct domains; an N-terminal heme-containing oxygen-binding domain and a C-terminal reductase domain with binding sites for FAD and NAD(P)H.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1159554:AFK67 RS20955
gene id: 1159554:AFK67_RS20955
uniprot id: A0A0K2P886
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

1159554:AFK67 RS05730
gene id: 1159554:AFK67_RS05730
uniprot id: A0A0K2NZT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

1159554:AFK67 RS03145
gene id: 1159554:AFK67_RS03145
uniprot id: A0A0K2NYY5
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1159554:AFK67 RS17625
gene id: 1159554:AFK67_RS17625
uniprot id: A0A0K2P5Y6
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

1159554:AFK67 RS03310
gene id: 1159554:AFK67_RS03310
uniprot id: A0A0K2NYI2
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS19570
gene id: 1159554:AFK67_RS19570
uniprot id: A0A0K2P7N0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1159554:AFK67 RS14895
gene id: 1159554:AFK67_RS14895
uniprot id: A0A0K2P4L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1159554:AFK67 RS05925
gene id: 1159554:AFK67_RS05925
uniprot id: A0A0K2NZX2
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1159554:AFK67 RS04460
gene id: 1159554:AFK67_RS04460
uniprot id: A0A0K2NZ04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1159554:AFK67 RS02620
gene id: 1159554:AFK67_RS02620
uniprot id: A0A0K2NY23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

1159554:AFK67 RS12180
gene id: 1159554:AFK67_RS12180
uniprot id: A0A0K2P387
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopD family.
messages: Cell inner membrane
messages: Involved in copper resistance. Appears to be involved in copper uptake.
messages: Membrane

1159554:AFK67 RS01105
gene id: 1159554:AFK67_RS01105
uniprot id: A0A0K2NX78
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
messages: Cytoplasm

1159554:AFK67 RS07615
gene id: 1159554:AFK67_RS07615
uniprot id: A0A0K2P0U1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane
messages: Part of a ferrous iron transporter composed of EfeU, EfeO and EfeB.
messages: Uptake of Fe(2+) ions across the membrane.

1159554:AFK67 RS08860
gene id: 1159554:AFK67_RS08860
uniprot id: A0A0K2P1D2
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1159554:AFK67 RS03580
gene id: 1159554:AFK67_RS03580
uniprot id: A0A0K2NYP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1159554:AFK67 RS20690
gene id: 1159554:AFK67_RS20690
uniprot id: A0A0K2P881
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1159554:AFK67 RS06510
gene id: 1159554:AFK67_RS06510
uniprot id: A0A0K2P039
names: Function
names: Similarity
messages: Belongs to the cycloisomerase 2 family.
messages: Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1159554:AFK67 RS17435
gene id: 1159554:AFK67_RS17435
uniprot id: A0A0K2P5V1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Monomer.

1159554:AFK67 RS18435
gene id: 1159554:AFK67_RS18435
uniprot id: A0A0K2P6F3
names: Similarity
messages: Belongs to the Fur family.

1159554:AFK67 RS04290
gene id: 1159554:AFK67_RS04290
uniprot id: A0A0K2NZ19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Crl family.
messages: Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32.
messages: Cytoplasm

1159554:AFK67 RS18865
gene id: 1159554:AFK67_RS18865
uniprot id: A0A0K2P6R8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1159554:AFK67 RS04075
gene id: 1159554:AFK67_RS04075
uniprot id: A0A0K2NYS0
names: Subcellular Location Annotation
messages: Cytoplasm

1159554:AFK67 RS11695
gene id: 1159554:AFK67_RS11695
uniprot id: A0A0K2P2T5
names: Similarity
messages: Belongs to the UPF0181 family.

1159554:AFK67 RS08890
gene id: 1159554:AFK67_RS08890
uniprot id: A0A0K2P7Q6
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS18790
gene id: 1159554:AFK67_RS18790
uniprot id: A0A0K2P797
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1159554:AFK67 RS01340
gene id: 1159554:AFK67_RS01340
uniprot id: A0A0K2NXF3
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

1159554:AFK67 RS06475
gene id: 1159554:AFK67_RS06475
uniprot id: A0A0K2P065
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1159554:AFK67 RS09075
gene id: 1159554:AFK67_RS09075
uniprot id: A0A0K2P1E5
names: Function
messages: Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.

1159554:AFK67 RS06245
gene id: 1159554:AFK67_RS06245
uniprot id: A0A0K2P0L2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1159554:AFK67 RS11115
gene id: 1159554:AFK67_RS11115
uniprot id: A0A0K2P2P2
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS16545
gene id: 1159554:AFK67_RS16545
uniprot id: A0A0K2P5H7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Syd family.
messages: Cell inner membrane
messages: Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.

1159554:AFK67 RS04880
gene id: 1159554:AFK67_RS04880
uniprot id: A0A0K2NZ91
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

1159554:AFK67 RS14020
gene id: 1159554:AFK67_RS14020
uniprot id: A0A0K2P414
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1159554:AFK67 RS06805
gene id: 1159554:AFK67_RS06805
uniprot id: A0A0K2P072
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1159554:AFK67 RS10295
gene id: 1159554:AFK67_RS10295
uniprot id: A0A0K2P283
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell inner membrane
messages: Cell membrane
messages: Forms a complex with MdtI.
messages: Membrane

1159554:AFK67 RS16825
gene id: 1159554:AFK67_RS16825
uniprot id: A0A0K2P5I4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1159554:AFK67 RS21310
gene id: 1159554:AFK67_RS21310
uniprot id: A0A0K2P8I0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1159554:AFK67 RS02335
gene id: 1159554:AFK67_RS02335
uniprot id: A0A0K2NY07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiU subfamily.
messages: Forms an heterodimer with UbiV.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiV, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

1159554:AFK67 RS01505
gene id: 1159554:AFK67_RS01505
uniprot id: A0A0K2NY42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: 3'-5' exonuclease that prefers single-stranded DNA and RNA. May play a role in the H(2)O(2)-induced DNA damage repair.
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. TatD subfamily.
messages: Cytoplasm
messages: Monomer.

1159554:AFK67 RS06455
gene id: 1159554:AFK67_RS06455
uniprot id: A0A0K2P003
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

1159554:AFK67 RS07715
gene id: 1159554:AFK67_RS07715
uniprot id: A0A0K2P0P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CsgA/CsgB family.
messages: Fimbrium

1159554:AFK67 RS03135
gene id: 1159554:AFK67_RS03135
uniprot id: A0A0K2NYB3
names: Similarity
messages: Belongs to the Smp family.

1159554:AFK67 RS15015
gene id: 1159554:AFK67_RS15015
uniprot id: A0A0K2P5A0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48 family. BepA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
messages: Periplasm

1159554:AFK67 RS01720
gene id: 1159554:AFK67_RS01720
uniprot id: A0A0K2NYA1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Divalent metal cations. Mg(2+) or Mn(2+).
messages: Homodimer.
messages: mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA. The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing. Has preference for mRNAs with a 5'-end purine. Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.

1159554:AFK67 RS06675
gene id: 1159554:AFK67_RS06675
uniprot id: A0A0K2P0A9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA-dependent ATPase and 5'-3' DNA helicase.

1159554:AFK67 RS04825
gene id: 1159554:AFK67_RS04825
uniprot id: A0A0K2NZ81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS05035
gene id: 1159554:AFK67_RS05035
uniprot id: A0A0K2NZC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

1159554:AFK67 RS11550
gene id: 1159554:AFK67_RS11550
uniprot id: A0A0K2P3E8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1159554:AFK67 RS06585
gene id: 1159554:AFK67_RS06585
uniprot id: A0A0K2P053
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1159554:AFK67 RS09615
gene id: 1159554:AFK67_RS09615
uniprot id: A0A0K2P1Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

1159554:AFK67 RS14185
gene id: 1159554:AFK67_RS14185
uniprot id: A0A0K2P451
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1159554:AFK67 RS09920
gene id: 1159554:AFK67_RS09920
uniprot id: A0A0K2P2N8
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1159554:AFK67 RS16950
gene id: 1159554:AFK67_RS16950
uniprot id: A0A0K2P5K1
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1159554:AFK67 RS03105
gene id: 1159554:AFK67_RS03105
uniprot id: A0A0K2NY75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1159554:AFK67 RS02280
gene id: 1159554:AFK67_RS02280
uniprot id: A0A0K2NXZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1159554:AFK67 RS09445
gene id: 1159554:AFK67_RS09445
uniprot id: A0A0K2P1S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.
messages: Membrane

1159554:AFK67 RS03985
gene id: 1159554:AFK67_RS03985
uniprot id: A0A0K2NYW1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

1159554:AFK67 RS01875
gene id: 1159554:AFK67_RS01875
uniprot id: A0A0K2NXM2
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1159554:AFK67 RS15415
gene id: 1159554:AFK67_RS15415
uniprot id: A0A0K2P4T3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1159554:AFK67 RS07570
gene id: 1159554:AFK67_RS07570
uniprot id: A0A0K2P0L9
names: Function
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Hydrolase RutD family.
messages: Involved in pyrimidine catabolism. May facilitate the hydrolysis of carbamate, a reaction that can also occur spontaneously.

1159554:AFK67 RS10270
gene id: 1159554:AFK67_RS10270
uniprot id: A0A0K2P280
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1159554:AFK67 RS17845
gene id: 1159554:AFK67_RS17845
uniprot id: A0A0K2P6S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TamA family.
messages: Cell outer membrane
messages: Membrane

1159554:AFK67 RS02010
gene id: 1159554:AFK67_RS02010
uniprot id: A0A0K2NXS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AFG1 ATPase family. ZapE subfamily.
messages: Cytoplasm
messages: Interacts with FtsZ.
messages: Reduces the stability of FtsZ polymers in the presence of ATP.

1159554:AFK67 RS10275
gene id: 1159554:AFK67_RS10275
uniprot id: A0A0K2P221
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS10180
gene id: 1159554:AFK67_RS10180
uniprot id: A0A0K2P2T4
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS04940
gene id: 1159554:AFK67_RS04940
uniprot id: A0A0K2NZE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1159554:AFK67 RS10515
gene id: 1159554:AFK67_RS10515
uniprot id: A0A0K2P289
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1159554:AFK67 RS01110
gene id: 1159554:AFK67_RS01110
uniprot id: A0A0K2NXB7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer.

1159554:AFK67 RS03545
gene id: 1159554:AFK67_RS03545
uniprot id: A0A0K2NYG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

1159554:AFK67 RS16690
gene id: 1159554:AFK67_RS16690
uniprot id: A0A0K2P5I5
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

1159554:AFK67 RS11010
gene id: 1159554:AFK67_RS11010
uniprot id: A0A0K2P376
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS07395
gene id: 1159554:AFK67_RS07395
uniprot id: A0A0K2P1B9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PqiA family.
messages: Component of a transport pathway that contributes to membrane integrity.
messages: Membrane

1159554:AFK67 RS02430
gene id: 1159554:AFK67_RS02430
uniprot id: A0A0K2P7Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the porin LamB (TC 1.B.3) family.
messages: Membrane

1159554:AFK67 RS08730
gene id: 1159554:AFK67_RS08730
uniprot id: A0A0K2P184
names: Similarity
messages: Belongs to the pyruvate kinase family.

1159554:AFK67 RS17610
gene id: 1159554:AFK67_RS17610
uniprot id: A0A0K2P834
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1159554:AFK67 RS02315
gene id: 1159554:AFK67_RS02315
uniprot id: A0A0K2NXT6
names: Similarity
names: Subunit
messages: Belongs to the beta-eliminating lyase family.
messages: Homotetramer.

1159554:AFK67 RS04385
gene id: 1159554:AFK67_RS04385
uniprot id: A0A0K2NYX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PqqD family.
messages: Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.
messages: Monomer. Interacts with PqqE.

1159554:AFK67 RS04840
gene id: 1159554:AFK67_RS04840
uniprot id: A0A0K2NZB9
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family. AroL subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The LID domain closes over the active site upon ATP binding.

1159554:AFK67 RS14150
gene id: 1159554:AFK67_RS14150
uniprot id: A0A0K2P443
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS03495
gene id: 1159554:AFK67_RS03495
uniprot id: A0A0K2NYI6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1159554:AFK67 RS02605
gene id: 1159554:AFK67_RS02605
uniprot id: A0A0K2NYP4
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS12570
gene id: 1159554:AFK67_RS12570
uniprot id: A0A0K2P3F1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1159554:AFK67 RS04380
gene id: 1159554:AFK67_RS04380
uniprot id: A0A0K2NZ23
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. PqqE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
messages: Interacts with PqqD. The interaction is necessary for activity of PqqE.

1159554:AFK67 RS12975
gene id: 1159554:AFK67_RS12975
uniprot id: A0A0K2P3H9
names: Function
names: Similarity
messages: Belongs to the AMP nucleosidase family.
messages: Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.

1159554:AFK67 RS07960
gene id: 1159554:AFK67_RS07960
uniprot id: A0A0K2P0Z9
names: Similarity
messages: Belongs to the fabD family.

1159554:AFK67 RS14055
gene id: 1159554:AFK67_RS14055
uniprot id: A0A0K2P474
names: Similarity
messages: Belongs to the CinA family.

1159554:AFK67 RS16355
gene id: 1159554:AFK67_RS16355
uniprot id: A0A0K2P7Y5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1159554:AFK67 RS06900
gene id: 1159554:AFK67_RS06900
uniprot id: A0A0K2P0F1
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS01100
gene id: 1159554:AFK67_RS01100
uniprot id: A0A0K2NXE0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1159554:AFK67 RS10450
gene id: 1159554:AFK67_RS10450
uniprot id: A0A0K2P2B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane
messages: Membrane

1159554:AFK67 RS16190
gene id: 1159554:AFK67_RS16190
uniprot id: A0A0K2P568
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS10555
gene id: 1159554:AFK67_RS10555
uniprot id: A0A0K2P2Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Cell inner membrane
messages: Membrane
messages: Zinc transporter. Acts as a Zn(2+):proton symporter, which likely mediates zinc ion uptake.

1159554:AFK67 RS13280
gene id: 1159554:AFK67_RS13280
uniprot id: A0A0K2P7V1
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1159554:AFK67 RS13100
gene id: 1159554:AFK67_RS13100
uniprot id: A0A0K2P3L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1159554:AFK67 RS18590
gene id: 1159554:AFK67_RS18590
uniprot id: A0A0K2P6G5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AceK family.
messages: Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
messages: Cytoplasm

1159554:AFK67 RS00005
gene id: 1159554:AFK67_RS00005
uniprot id: A0A0K2NWM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1159554:AFK67 RS00965
gene id: 1159554:AFK67_RS00965
uniprot id: A0A0K2P7L1
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activity of this regulatory enzyme is affected by several metabolites. Allosterically and non-competitively inhibited by fructose 1,6-bisphosphate (FBP) and unphosphorylated phosphocarrier protein EIIA-Glc (III-Glc), an integral component of the bacterial phosphotransferase (PTS) system.
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium). Heterodimer with EIIA-Glc. Binds 1 zinc ion per glycerol kinase EIIA-Glc dimer. The zinc ion is important for dimerization.
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

1159554:AFK67 RS16385
gene id: 1159554:AFK67_RS16385
uniprot id: A0A0K2P595
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.

1159554:AFK67 RS18845
gene id: 1159554:AFK67_RS18845
uniprot id: A0A0K2P6P7
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1159554:AFK67 RS06630
gene id: 1159554:AFK67_RS06630
uniprot id: A0A0K2P037
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS17550
gene id: 1159554:AFK67_RS17550
uniprot id: A0A0K2P5Y9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1159554:AFK67 RS14285
gene id: 1159554:AFK67_RS14285
uniprot id: A0A0K2P467
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1159554:AFK67 RS09450
gene id: 1159554:AFK67_RS09450
uniprot id: A0A0K2P1M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS01495
gene id: 1159554:AFK67_RS01495
uniprot id: A0A0K2NXI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1159554:AFK67 RS03960
gene id: 1159554:AFK67_RS03960
uniprot id: A0A0K2NYV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BtuF family.
messages: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC.
messages: Periplasm
messages: The complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF).

1159554:AFK67 RS06130
gene id: 1159554:AFK67_RS06130
uniprot id: A0A0K2NZU1
names: Similarity
messages: Belongs to the asparagine synthetase family.

1159554:AFK67 RS11785
gene id: 1159554:AFK67_RS11785
uniprot id: A0A0K2P3K0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS03625
gene id: 1159554:AFK67_RS03625
uniprot id: A0A0K2NYL0
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.

1159554:AFK67 RS09210
gene id: 1159554:AFK67_RS09210
uniprot id: A0A0K2P1H1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1159554:AFK67 RS08540
gene id: 1159554:AFK67_RS08540
uniprot id: A0A0K2P1V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Metabolite:H+ Symporter (MHS) family (TC 2.A.1.6) family.
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS20060
gene id: 1159554:AFK67_RS20060
uniprot id: A0A0K2P799
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS08665
gene id: 1159554:AFK67_RS08665
uniprot id: A0A0K2P1Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.
messages: Membrane

1159554:AFK67 RS19125
gene id: 1159554:AFK67_RS19125
uniprot id: A0A0K2P7F7
names: Similarity
messages: Belongs to the HSP15 family.

1159554:AFK67 RS12230
gene id: 1159554:AFK67_RS12230
uniprot id: A0A0K2P393
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

1159554:AFK67 RS04560
gene id: 1159554:AFK67_RS04560
uniprot id: A0A0K2NZ18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1159554:AFK67 RS18785
gene id: 1159554:AFK67_RS18785
uniprot id: A0A0K2P6Q4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1159554:AFK67 RS14580
gene id: 1159554:AFK67_RS14580
uniprot id: A0A0K2P509
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1159554:AFK67 RS14610
gene id: 1159554:AFK67_RS14610
uniprot id: A0A0K2P4G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

1159554:AFK67 RS17915
gene id: 1159554:AFK67_RS17915
uniprot id: A0A0K2P6A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

1159554:AFK67 RS15030
gene id: 1159554:AFK67_RS15030
uniprot id: A0A0K2P4K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1159554:AFK67 RS14155
gene id: 1159554:AFK67_RS14155
uniprot id: A0A0K2P447
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1159554:AFK67 RS08715
gene id: 1159554:AFK67_RS08715
uniprot id: A0A0K2P1E9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SufE family.
messages: Cytoplasm
messages: Homodimer. Interacts with SufS.
messages: Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process.

1159554:AFK67 RS19405
gene id: 1159554:AFK67_RS19405
uniprot id: A0A0K2P721
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1159554:AFK67 RS05020
gene id: 1159554:AFK67_RS05020
uniprot id: A0A0K2P011
names: Similarity
messages: Belongs to the UPF0234 family.

1159554:AFK67 RS05830
gene id: 1159554:AFK67_RS05830
uniprot id: A0A0K2NZU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Fes family.
messages: Cytoplasm

1159554:AFK67 RS04350
gene id: 1159554:AFK67_RS04350
uniprot id: A0A0K2NYX0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.

1159554:AFK67 RS18490
gene id: 1159554:AFK67_RS18490
uniprot id: A0A0K2P6G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins.
messages: Periplasm

1159554:AFK67 RS15065
gene id: 1159554:AFK67_RS15065
uniprot id: A0A0K2P5B3
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1159554:AFK67 RS14545
gene id: 1159554:AFK67_RS14545
uniprot id: A0A0K2P4G1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1159554:AFK67 RS07155
gene id: 1159554:AFK67_RS07155
uniprot id: A0A0K2P0L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

1159554:AFK67 RS06185
gene id: 1159554:AFK67_RS06185
uniprot id: A0A0K2NZX3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

1159554:AFK67 RS18920
gene id: 1159554:AFK67_RS18920
uniprot id: A0A0K2P7C1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAD(P)H dehydrogenase (quinone) family. KefG subfamily.
messages: Cell inner membrane
messages: Interacts with KefB.
messages: Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB.

1159554:AFK67 RS05185
gene id: 1159554:AFK67_RS05185
uniprot id: A0A0K2NZI3
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1159554:AFK67 RS17495
gene id: 1159554:AFK67_RS17495
uniprot id: A0A0K2P7Y4
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS12935
gene id: 1159554:AFK67_RS12935
uniprot id: A0A0K2P3L2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MtfA family.
messages: Cytoplasm
messages: Interacts with Mlc.
messages: Involved in the regulation of ptsG expression by binding and inactivating Mlc.

1159554:AFK67 RS19280
gene id: 1159554:AFK67_RS19280
uniprot id: A0A0K2P6Z7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1159554:AFK67 RS08725
gene id: 1159554:AFK67_RS08725
uniprot id: A0A0K2P1D7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane.
messages: Belongs to the Lpp family.
messages: Cell outer membrane
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: cell wall

1159554:AFK67 RS03390
gene id: 1159554:AFK67_RS03390
uniprot id: A0A0K2NYD0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
messages: Homodimer.

1159554:AFK67 RS09675
gene id: 1159554:AFK67_RS09675
uniprot id: A0A0K2P1W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

1159554:AFK67 RS02110
gene id: 1159554:AFK67_RS02110
uniprot id: A0A0K2NYG1
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1159554:AFK67 RS06350
gene id: 1159554:AFK67_RS06350
uniprot id: A0A0K2P045
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1159554:AFK67 RS10905
gene id: 1159554:AFK67_RS10905
uniprot id: A0A0K2P2J3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

1159554:AFK67 RS13460
gene id: 1159554:AFK67_RS13460
uniprot id: A0A0K2P3V6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinone-dependent D-lactate dehydrogenase family.
messages: Catalyzes the oxidation of D-lactate to pyruvate.
messages: Cell inner membrane

1159554:AFK67 RS01545
gene id: 1159554:AFK67_RS01545
uniprot id: A0A0K2NXJ0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
messages: Binds 2 manganese ions per subunit.
messages: Splits dipeptides with a prolyl residue in the C-terminal position.

1159554:AFK67 RS08160
gene id: 1159554:AFK67_RS08160
uniprot id: A0A0K2P138
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

1159554:AFK67 RS20225
gene id: 1159554:AFK67_RS20225
uniprot id: A0A0K2P7G1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1159554:AFK67 RS17980
gene id: 1159554:AFK67_RS17980
uniprot id: A0A0K2P669
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1159554:AFK67 RS07160
gene id: 1159554:AFK67_RS07160
uniprot id: A0A0K2P175
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

1159554:AFK67 RS16040
gene id: 1159554:AFK67_RS16040
uniprot id: A0A0K2P575
names: Function
names: Similarity
names: Subunit
messages: Belongs to the rusA family.
messages: Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of CC dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of RuvAB or RuvC.
messages: Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC.
messages: Homodimer.

1159554:AFK67 RS12810
gene id: 1159554:AFK67_RS12810
uniprot id: A0A0K2P3L3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

1159554:AFK67 RS08380
gene id: 1159554:AFK67_RS08380
uniprot id: A0A0K2P1T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S49 family.
messages: Cell inner membrane

1159554:AFK67 RS05720
gene id: 1159554:AFK67_RS05720
uniprot id: A0A0K2NZM3
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1159554:AFK67 RS01125
gene id: 1159554:AFK67_RS01125
uniprot id: A0A0K2P7Q7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily.
messages: Cell outer membrane
messages: Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1159554:AFK67 RS08820
gene id: 1159554:AFK67_RS08820
uniprot id: A0A0K2P208
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS03835
gene id: 1159554:AFK67_RS03835
uniprot id: A0A0K2NYM2
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1159554:AFK67 RS01895
gene id: 1159554:AFK67_RS01895
uniprot id: A0A0K2NXS7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

1159554:AFK67 RS01805
gene id: 1159554:AFK67_RS01805
uniprot id: A0A0K2NYB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS10100
gene id: 1159554:AFK67_RS10100
uniprot id: A0A0K2P263
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS05950
gene id: 1159554:AFK67_RS05950
uniprot id: A0A0K2NZX7
names: Subcellular Location Annotation
messages: Cytoplasm

1159554:AFK67 RS04565
gene id: 1159554:AFK67_RS04565
uniprot id: A0A0K2NZ39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1159554:AFK67 RS07410
gene id: 1159554:AFK67_RS07410
uniprot id: A0A0K2P0L3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

1159554:AFK67 RS15230
gene id: 1159554:AFK67_RS15230
uniprot id: A0A0K2P4Q7
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1159554:AFK67 RS00975
gene id: 1159554:AFK67_RS00975
uniprot id: A0A0K2NXB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapB family.
messages: Cytoplasm
messages: Homodimer. The ends of the coiled-coil dimer bind to each other, forming polymers. Interacts with FtsZ.
messages: Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.

1159554:AFK67 RS18045
gene id: 1159554:AFK67_RS18045
uniprot id: A0A0K2P6X8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1159554:AFK67 RS01890
gene id: 1159554:AFK67_RS01890
uniprot id: A0A0K2NYC5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

1159554:AFK67 RS13025
gene id: 1159554:AFK67_RS13025
uniprot id: A0A0K2P4A2
names: Similarity
messages: Belongs to the UPF0265 family.

1159554:AFK67 RS14385
gene id: 1159554:AFK67_RS14385
uniprot id: A0A0K2P4D4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1159554:AFK67 RS19640
gene id: 1159554:AFK67_RS19640
uniprot id: A0A0K2P718
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

1159554:AFK67 RS12400
gene id: 1159554:AFK67_RS12400
uniprot id: A0A0K2P384
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1159554:AFK67 RS12280
gene id: 1159554:AFK67_RS12280
uniprot id: A0A0K2P3A1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1159554:AFK67 RS16500
gene id: 1159554:AFK67_RS16500
uniprot id: A0A0K2P617
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1159554:AFK67 RS19810
gene id: 1159554:AFK67_RS19810
uniprot id: A0A0K2P777
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1159554:AFK67 RS16575
gene id: 1159554:AFK67_RS16575
uniprot id: A0A0K2P631
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
messages: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
messages: Cytoplasm
messages: Monomer.

1159554:AFK67 RS14125
gene id: 1159554:AFK67_RS14125
uniprot id: A0A0K2P437
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS14015
gene id: 1159554:AFK67_RS14015
uniprot id: A0A0K2P457
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Autophosphorylated. Activation probably requires a transfer of a phosphate group from a His in the transmitter domain to an Asp in the receiver domain.
messages: Belongs to the RcsC family.
messages: Cell inner membrane
messages: Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane-associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB.
messages: Interacts with RcsD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1159554:AFK67 RS14000
gene id: 1159554:AFK67_RS14000
uniprot id: A0A0K2P416
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Gram-negative porin family.
messages: Cell outer membrane
messages: Homotrimer.
messages: Membrane

1159554:AFK67 RS01205
gene id: 1159554:AFK67_RS01205
uniprot id: A0A0K2NXX7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1159554:AFK67 RS20370
gene id: 1159554:AFK67_RS20370
uniprot id: A0A0K2P7G0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1159554:AFK67 RS04040
gene id: 1159554:AFK67_RS04040
uniprot id: A0A0K2NZG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery.

1159554:AFK67 RS20230
gene id: 1159554:AFK67_RS20230
uniprot id: A0A0K2P7C7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1159554:AFK67 RS06490
gene id: 1159554:AFK67_RS06490
uniprot id: A0A0K2P074
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1159554:AFK67 RS13550
gene id: 1159554:AFK67_RS13550
uniprot id: A0A0K2P3U4
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

1159554:AFK67 RS02125
gene id: 1159554:AFK67_RS02125
uniprot id: A0A0K2NXT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptC family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.
messages: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1159554:AFK67 RS01390
gene id: 1159554:AFK67_RS01390
uniprot id: A0A0K2NXG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1159554:AFK67 RS19705
gene id: 1159554:AFK67_RS19705
uniprot id: A0A0K2P758
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane.

1159554:AFK67 RS17250
gene id: 1159554:AFK67_RS17250
uniprot id: A0A0K2P5R5
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

1159554:AFK67 RS04235
gene id: 1159554:AFK67_RS04235
uniprot id: A0A0K2NZ10
names: Function
names: Subunit
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.
messages: The DNA polymerase holoenzyme is a complex that contains 10 different types of subunits. These subunits are organized into 3 functionally essential subassemblies: the pol III core, the beta sliding clamp processivity factor and the clamp-loading complex. The pol III core (subunits alpha,epsilon and theta) contains the polymerase and the 3'-5' exonuclease proofreading activities. The polymerase is tethered to the template via the sliding clamp processivity factor. The clamp-loading complex assembles the beta processivity factor onto the primer template and plays a central role in the organization and communication at the replication fork. This complex contains delta, delta', psi and chi, and copies of either or both of two different DnaX proteins, gamma and tau.

1159554:AFK67 RS08930
gene id: 1159554:AFK67_RS08930
uniprot id: A0A0K2P1H8
names: Function
messages: Repressor involved in choline regulation of the bet genes.
messages: Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine.

1159554:AFK67 RS15855
gene id: 1159554:AFK67_RS15855
uniprot id: A0A0K2P505
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1159554:AFK67 RS08030
gene id: 1159554:AFK67_RS08030
uniprot id: A0A0K2P1M7
names: Function
names: Similarity
messages: Belongs to the thiamine kinase family.
messages: Catalyzes the phosphorylation of thiamine to thiamine phosphate.

1159554:AFK67 RS17455
gene id: 1159554:AFK67_RS17455
uniprot id: A0A0K2P5Y8
names: Similarity
messages: Belongs to the CitG/MdcB family.

1159554:AFK67 RS01500
gene id: 1159554:AFK67_RS01500
uniprot id: A0A0K2NXM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1159554:AFK67 RS17555
gene id: 1159554:AFK67_RS17555
uniprot id: A0A0K2P619
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

1159554:AFK67 RS05555
gene id: 1159554:AFK67_RS05555
uniprot id: A0A0K2NZQ7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1159554:AFK67 RS11220
gene id: 1159554:AFK67_RS11220
uniprot id: A0A0K2P2L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1159554:AFK67 RS04680
gene id: 1159554:AFK67_RS04680
uniprot id: A0A0K2NZV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1159554:AFK67 RS08345
gene id: 1159554:AFK67_RS08345
uniprot id: A0A0K2P178
names: Similarity
messages: Belongs to the MipA/OmpV family.

1159554:AFK67 RS20305
gene id: 1159554:AFK67_RS20305
uniprot id: A0A0K2P7H7
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1159554:AFK67 RS14445
gene id: 1159554:AFK67_RS14445
uniprot id: A0A0K2P4E5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadJ) and two beta chains (FadI).

1159554:AFK67 RS07010
gene id: 1159554:AFK67_RS07010
uniprot id: A0A0K2P130
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

1159554:AFK67 RS13735
gene id: 1159554:AFK67_RS13735
uniprot id: A0A0K2P4M0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1159554:AFK67 RS18495
gene id: 1159554:AFK67_RS18495
uniprot id: A0A0K2P6K4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MalK), two transmembrane proteins (MalG and MalF) and a solute-binding protein (MalE).

1159554:AFK67 RS16675
gene id: 1159554:AFK67_RS16675
uniprot id: A0A0K2P5F4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1159554:AFK67 RS20405
gene id: 1159554:AFK67_RS20405
uniprot id: A0A0K2P7G4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

1159554:AFK67 RS03830
gene id: 1159554:AFK67_RS03830
uniprot id: A0A0K2NYT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm
messages: Purine salvage pathway enzyme which catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of hypoxanthine to yield IMP (inosine 5'-monophosphate). To a lesser extent, can also act on guanine leading to GMP, but shows a highly less efficient activity with xanthine.

1159554:AFK67 RS19265
gene id: 1159554:AFK67_RS19265
uniprot id: A0A0K2P6X1
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Removes maltotriose and maltotetraose chains that are attached by 1,6-alpha-linkage to the limit dextrin main chain, generating a debranched limit dextrin.

1159554:AFK67 RS02830
gene id: 1159554:AFK67_RS02830
uniprot id: A0A0K2NY63
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

1159554:AFK67 RS05285
gene id: 1159554:AFK67_RS05285
uniprot id: A0A0K2P056
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1159554:AFK67 RS18580
gene id: 1159554:AFK67_RS18580
uniprot id: A0A0K2P766
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1159554:AFK67 RS14575
gene id: 1159554:AFK67_RS14575
uniprot id: A0A0K2P4G6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1159554:AFK67 RS06355
gene id: 1159554:AFK67_RS06355
uniprot id: A0A0K2NZY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS12585
gene id: 1159554:AFK67_RS12585
uniprot id: A0A0K2P3H6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease subfamily.
messages: Cell inner membrane
messages: Involved in transporting aromatic amino acids across the cytoplasmic membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1159554:AFK67 RS14960
gene id: 1159554:AFK67_RS14960
uniprot id: A0A0K2P4N6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

1159554:AFK67 RS07965
gene id: 1159554:AFK67_RS07965
uniprot id: A0A0K2P0U2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1159554:AFK67 RS03530
gene id: 1159554:AFK67_RS03530
uniprot id: A0A0K2NYN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS13210
gene id: 1159554:AFK67_RS13210
uniprot id: A0A0K2P4D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1159554:AFK67 RS10385
gene id: 1159554:AFK67_RS10385
uniprot id: A0A0K2P2B8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

1159554:AFK67 RS08440
gene id: 1159554:AFK67_RS08440
uniprot id: A0A0K2P182
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinylarginine dihydrolase family.
messages: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
messages: Homodimer.

1159554:AFK67 RS19210
gene id: 1159554:AFK67_RS19210
uniprot id: A0A0K2P6T1
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1159554:AFK67 RS11300
gene id: 1159554:AFK67_RS11300
uniprot id: A0A0K2P2M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS14470
gene id: 1159554:AFK67_RS14470
uniprot id: A0A0K2P4A1
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

1159554:AFK67 RS04455
gene id: 1159554:AFK67_RS04455
uniprot id: A0A0K2NZ52
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1159554:AFK67 RS02515
gene id: 1159554:AFK67_RS02515
uniprot id: A0A0K2NY04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Has been proposed to be a redox modulator.
messages: Membrane

1159554:AFK67 RS03640
gene id: 1159554:AFK67_RS03640
uniprot id: A0A0K2NYP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS10795
gene id: 1159554:AFK67_RS10795
uniprot id: A0A0K2P2I6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNR ribonuclease family. RNase II subfamily.
messages: Cytoplasm
messages: Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.

1159554:AFK67 RS02385
gene id: 1159554:AFK67_RS02385
uniprot id: A0A0K2NY16
names: Similarity
messages: Belongs to the UPF0102 family.

1159554:AFK67 RS14270
gene id: 1159554:AFK67_RS14270
uniprot id: A0A0K2P4B5
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1159554:AFK67 RS03615
gene id: 1159554:AFK67_RS03615
uniprot id: A0A0K2NYP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1159554:AFK67 RS11055
gene id: 1159554:AFK67_RS11055
uniprot id: A0A0K2P2N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

1159554:AFK67 RS06745
gene id: 1159554:AFK67_RS06745
uniprot id: A0A0K2P0X0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1159554:AFK67 RS17125
gene id: 1159554:AFK67_RS17125
uniprot id: A0A0K2P5N8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1159554:AFK67 RS01730
gene id: 1159554:AFK67_RS01730
uniprot id: A0A0K2NXK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

1159554:AFK67 RS07335
gene id: 1159554:AFK67_RS07335
uniprot id: A0A0K2P0P5
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

1159554:AFK67 RS02135
gene id: 1159554:AFK67_RS02135
uniprot id: A0A0K2NYG6
names: Similarity
names: Subunit
messages: Belongs to the SIS family. GutQ/KpsF subfamily.
messages: Homotetramer.

1159554:AFK67 RS10885
gene id: 1159554:AFK67_RS10885
uniprot id: A0A0K2P2E4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1159554:AFK67 RS14420
gene id: 1159554:AFK67_RS14420
uniprot id: A0A0K2P4Y2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1159554:AFK67 RS19020
gene id: 1159554:AFK67_RS19020
uniprot id: A0A0K2P7D8
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS10220
gene id: 1159554:AFK67_RS10220
uniprot id: A0A0K2P211
names: Function
messages: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds.

1159554:AFK67 RS09135
gene id: 1159554:AFK67_RS09135
uniprot id: A0A0K2P1H9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

1159554:AFK67 RS07525
gene id: 1159554:AFK67_RS07525
uniprot id: A0A0K2P0N2
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1159554:AFK67 RS05505
gene id: 1159554:AFK67_RS05505
uniprot id: A0A0K2NZP9
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1159554:AFK67 RS10985
gene id: 1159554:AFK67_RS10985
uniprot id: A0A0K2P2K4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Homodimer. Forms a complex with the accessory proteins ExbB and ExbD.
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

1159554:AFK67 RS04215
gene id: 1159554:AFK67_RS04215
uniprot id: A0A0K2NZJ8
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1159554:AFK67 RS09745
gene id: 1159554:AFK67_RS09745
uniprot id: A0A0K2P1U4
names: Similarity
messages: Belongs to the manganese catalase family.

1159554:AFK67 RS03865
gene id: 1159554:AFK67_RS03865
uniprot id: A0A0K2NYQ6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1159554:AFK67 RS08150
gene id: 1159554:AFK67_RS08150
uniprot id: A0A0K2P146
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis. Sulfur is provided by IscS, via a sulfur-relay system. Binds ATP and its substrate tRNAs.
messages: Cytoplasm
messages: Interacts with TusE.

1159554:AFK67 RS08095
gene id: 1159554:AFK67_RS08095
uniprot id: A0A0K2P0Z1
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-93 and Arg-96) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase that specifically removes acetyl groups on target proteins. Also acts as a protein-lysine deacylase by mediating protein desuccinylation and de-2-hydroxyisobutyrylation. Modulates the activities of several proteins which are inactive in their acylated form.

1159554:AFK67 RS06825
gene id: 1159554:AFK67_RS06825
uniprot id: A0A0K2P0Y9
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1159554:AFK67 RS14375
gene id: 1159554:AFK67_RS14375
uniprot id: A0A0K2P817
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a regulator of flagellar gene expression by modulating the protein level of the anti sigma factor FlgM upon sensing ring completion or hook elongation. Flk could inhibit FlgM secretion by acting as a braking system for the flagellar-associated type III secretion system.
messages: Belongs to the flk family.
messages: Cell inner membrane

1159554:AFK67 RS13645
gene id: 1159554:AFK67_RS13645
uniprot id: A0A0K2P4K7
names: Similarity
messages: Belongs to the peptidase C40 family.

1159554:AFK67 RS13370
gene id: 1159554:AFK67_RS13370
uniprot id: A0A0K2P3V9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily.
messages: Binds 1 Mg(2+) ion per subunit. Ca(2+) may be able to substitute.
messages: Cytoplasm
messages: Probably phosphorylates lipids; the in vivo substrate is unknown.

1159554:AFK67 RS19415
gene id: 1159554:AFK67_RS19415
uniprot id: A0A0K2P7K1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

1159554:AFK67 RS11650
gene id: 1159554:AFK67_RS11650
uniprot id: A0A0K2P2T6
names: Similarity
messages: Belongs to the RutC family.

1159554:AFK67 RS13320
gene id: 1159554:AFK67_RS13320
uniprot id: A0A0K2P3V0
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1159554:AFK67 RS00020
gene id: 1159554:AFK67_RS00020
uniprot id: A0A0K2NXD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1159554:AFK67 RS03575
gene id: 1159554:AFK67_RS03575
uniprot id: A0A0K2NYK1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1159554:AFK67 RS11175
gene id: 1159554:AFK67_RS11175
uniprot id: A0A0K2P2Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1159554:AFK67 RS18160
gene id: 1159554:AFK67_RS18160
uniprot id: A0A0K2P6A4
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

1159554:AFK67 RS06660
gene id: 1159554:AFK67_RS06660
uniprot id: A0A0K2P071
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1159554:AFK67 RS17165
gene id: 1159554:AFK67_RS17165
uniprot id: A0A0K2P6D0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1159554:AFK67 RS17660
gene id: 1159554:AFK67_RS17660
uniprot id: A0A0K2P637
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1159554:AFK67 RS12355
gene id: 1159554:AFK67_RS12355
uniprot id: A0A0K2P3B5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1159554:AFK67 RS14120
gene id: 1159554:AFK67_RS14120
uniprot id: A0A0K2P478
names: Function
names: Similarity
messages: Belongs to the isochorismate synthase family.
messages: Catalyzes the conversion of chorismate to isochorismate.

1159554:AFK67 RS17850
gene id: 1159554:AFK67_RS17850
uniprot id: A0A0K2P658
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1159554:AFK67 RS11745
gene id: 1159554:AFK67_RS11745
uniprot id: A0A0K2P2U3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

1159554:AFK67 RS10740
gene id: 1159554:AFK67_RS10740
uniprot id: A0A0K2P2H6
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS08625
gene id: 1159554:AFK67_RS08625
uniprot id: A0A0K2P162
names: Similarity
messages: Belongs to the peptidase C40 family.

1159554:AFK67 RS02935
gene id: 1159554:AFK67_RS02935
uniprot id: A0A0K2NY49
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS20315
gene id: 1159554:AFK67_RS20315
uniprot id: A0A0K2P7E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

1159554:AFK67 RS17930
gene id: 1159554:AFK67_RS17930
uniprot id: A0A0K2P662
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1159554:AFK67 RS19175
gene id: 1159554:AFK67_RS19175
uniprot id: A0A0K2P7G6
names: Function
names: Similarity
messages: Belongs to the FeoC family.
messages: May function as a transcriptional regulator that controls feoABC expression.

1159554:AFK67 RS05545
gene id: 1159554:AFK67_RS05545
uniprot id: A0A0K2NZJ2
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS08255
gene id: 1159554:AFK67_RS08255
uniprot id: A0A0K2P120
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

1159554:AFK67 RS20910
gene id: 1159554:AFK67_RS20910
uniprot id: A0A0K2P879
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS07555
gene id: 1159554:AFK67_RS07555
uniprot id: A0A0K2P0T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1159554:AFK67 RS11865
gene id: 1159554:AFK67_RS11865
uniprot id: A0A0K2P310
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1159554:AFK67 RS10070
gene id: 1159554:AFK67_RS10070
uniprot id: A0A0K2P257
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS07595
gene id: 1159554:AFK67_RS07595
uniprot id: A0A0K2P0M3
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

1159554:AFK67 RS01015
gene id: 1159554:AFK67_RS01015
uniprot id: A0A0K2NXE1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1159554:AFK67 RS18230
gene id: 1159554:AFK67_RS18230
uniprot id: A0A0K2P7Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdgT transporter family.
messages: Catalyzes the proton-dependent uptake of 2-keto-3-deoxygluconate (KDG) into the cell.
messages: Cell membrane

1159554:AFK67 RS14065
gene id: 1159554:AFK67_RS14065
uniprot id: A0A0K2P468
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS12345
gene id: 1159554:AFK67_RS12345
uniprot id: A0A0K2P362
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

1159554:AFK67 RS08375
gene id: 1159554:AFK67_RS08375
uniprot id: A0A0K2P7V4
names: Similarity
messages: Belongs to the asparaginase 1 family.

1159554:AFK67 RS10820
gene id: 1159554:AFK67_RS10820
uniprot id: A0A0K2P2J1
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

1159554:AFK67 RS07245
gene id: 1159554:AFK67_RS07245
uniprot id: A0A0K2P0M5
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1159554:AFK67 RS07865
gene id: 1159554:AFK67_RS07865
uniprot id: A0A0K2P0S3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1159554:AFK67 RS13510
gene id: 1159554:AFK67_RS13510
uniprot id: A0A0K2P4I4
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS04305
gene id: 1159554:AFK67_RS04305
uniprot id: A0A0K2NZ13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1159554:AFK67 RS16715
gene id: 1159554:AFK67_RS16715
uniprot id: A0A0K2P5J0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. LplT (TC 2.A.1.42) family.
messages: Catalyzes the facilitated diffusion of 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) into the cell.
messages: Cell membrane

1159554:AFK67 RS21175
gene id: 1159554:AFK67_RS21175
uniprot id: A0A0K2P8C4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1159554:AFK67 RS01810
gene id: 1159554:AFK67_RS01810
uniprot id: A0A0K2NXR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS16165
gene id: 1159554:AFK67_RS16165
uniprot id: A0A0K2P561
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1159554:AFK67 RS01245
gene id: 1159554:AFK67_RS01245
uniprot id: A0A0K2NXD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. WecA subfamily.
messages: Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55).
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS19450
gene id: 1159554:AFK67_RS19450
uniprot id: A0A0K2P707
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

1159554:AFK67 RS12745
gene id: 1159554:AFK67_RS12745
uniprot id: A0A0K2P3E2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1159554:AFK67 RS02095
gene id: 1159554:AFK67_RS02095
uniprot id: A0A0K2P7P9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RapZ-like family. RapZ subfamily.
messages: Homotrimer.
messages: Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS.

1159554:AFK67 RS15365
gene id: 1159554:AFK67_RS15365
uniprot id: A0A0K2P4S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1159554:AFK67 RS17395
gene id: 1159554:AFK67_RS17395
uniprot id: A0A0K2P6I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1159554:AFK67 RS07875
gene id: 1159554:AFK67_RS07875
uniprot id: A0A0K2P0Z3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1159554:AFK67 RS01070
gene id: 1159554:AFK67_RS01070
uniprot id: A0A0K2NXV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

1159554:AFK67 RS10310
gene id: 1159554:AFK67_RS10310
uniprot id: A0A0K2P2A2
names: Similarity
messages: Belongs to the peptidase S24 family.

1159554:AFK67 RS13625
gene id: 1159554:AFK67_RS13625
uniprot id: A0A0K2P3Y6
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

1159554:AFK67 RS08590
gene id: 1159554:AFK67_RS08590
uniprot id: A0A0K2P1W7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1159554:AFK67 RS10155
gene id: 1159554:AFK67_RS10155
uniprot id: A0A0K2P2T0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1159554:AFK67 RS11595
gene id: 1159554:AFK67_RS11595
uniprot id: A0A0K2P2S5
names: Similarity
messages: Belongs to the UPF0260 family.

1159554:AFK67 RS00990
gene id: 1159554:AFK67_RS00990
uniprot id: A0A0K2NXD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1159554:AFK67 RS09090
gene id: 1159554:AFK67_RS09090
uniprot id: A0A0K2P1L5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1159554:AFK67 RS10880
gene id: 1159554:AFK67_RS10880
uniprot id: A0A0K2P2I8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1159554:AFK67 RS15590
gene id: 1159554:AFK67_RS15590
uniprot id: A0A0K2P4V7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1159554:AFK67 RS18645
gene id: 1159554:AFK67_RS18645
uniprot id: A0A0K2P6I5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

1159554:AFK67 RS00085
gene id: 1159554:AFK67_RS00085
uniprot id: A0A0K2NWT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

1159554:AFK67 RS06885
gene id: 1159554:AFK67_RS06885
uniprot id: A0A0K2P0E4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS02270
gene id: 1159554:AFK67_RS02270
uniprot id: A0A0K2P7L7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1159554:AFK67 RS16460
gene id: 1159554:AFK67_RS16460
uniprot id: A0A0K2P5B1
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1159554:AFK67 RS02290
gene id: 1159554:AFK67_RS02290
uniprot id: A0A0K2NXW8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1159554:AFK67 RS04100
gene id: 1159554:AFK67_RS04100
uniprot id: A0A0K2NYS6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1159554:AFK67 RS14900
gene id: 1159554:AFK67_RS14900
uniprot id: A0A0K2P4H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1159554:AFK67 RS07980
gene id: 1159554:AFK67_RS07980
uniprot id: A0A0K2P1L7
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1159554:AFK67 RS15140
gene id: 1159554:AFK67_RS15140
uniprot id: A0A0K2P4R7
names: Function
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.
messages: Protects the bacterial cell from host peptidases.

1159554:AFK67 RS18295
gene id: 1159554:AFK67_RS18295
uniprot id: A0A0K2P6F0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1159554:AFK67 RS17480
gene id: 1159554:AFK67_RS17480
uniprot id: A0A0K2P5Z3
names: Function
messages: Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase.

1159554:AFK67 RS21000
gene id: 1159554:AFK67_RS21000
uniprot id: A0A0K2P8X2
names: Similarity
messages: Belongs to the ParB family.

1159554:AFK67 RS14565
gene id: 1159554:AFK67_RS14565
uniprot id: A0A0K2P4B3
names: Similarity
messages: Belongs to the TPP enzyme family.

1159554:AFK67 RS20495
gene id: 1159554:AFK67_RS20495
uniprot id: A0A0K2P7L4
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1159554:AFK67 RS17750
gene id: 1159554:AFK67_RS17750
uniprot id: A0A0K2P611
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

1159554:AFK67 RS20925
gene id: 1159554:AFK67_RS20925
uniprot id: A0A0K2P8B2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.

1159554:AFK67 RS19115
gene id: 1159554:AFK67_RS19115
uniprot id: A0A0K2P6S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IgaA family.
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS17030
gene id: 1159554:AFK67_RS17030
uniprot id: A0A0K2P5M8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1159554:AFK67 RS08080
gene id: 1159554:AFK67_RS08080
uniprot id: A0A0K2P1N7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

1159554:AFK67 RS15220
gene id: 1159554:AFK67_RS15220
uniprot id: A0A0K2P5G0
names: Cofactor
names: Function
messages: Binds 1 [2Fe-2S] cluster.
messages: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.

1159554:AFK67 RS00370
gene id: 1159554:AFK67_RS00370
uniprot id: A0A0K2NWT5
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS20600
gene id: 1159554:AFK67_RS20600
uniprot id: A0A0K2P822
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS07240
gene id: 1159554:AFK67_RS07240
uniprot id: A0A0K2P191
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS07360
gene id: 1159554:AFK67_RS07360
uniprot id: A0A0K2P0Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

1159554:AFK67 RS03325
gene id: 1159554:AFK67_RS03325
uniprot id: A0A0K2NYJ5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1159554:AFK67 RS00780
gene id: 1159554:AFK67_RS00780
uniprot id: A0A0K2NX56
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Membrane

1159554:AFK67 RS08085
gene id: 1159554:AFK67_RS08085
uniprot id: A0A0K2P124
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1159554:AFK67 RS03070
gene id: 1159554:AFK67_RS03070
uniprot id: A0A0K2NYX3
names: Function
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown.

1159554:AFK67 RS18675
gene id: 1159554:AFK67_RS18675
uniprot id: A0A0K2P6I9
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1159554:AFK67 RS04390
gene id: 1159554:AFK67_RS04390
uniprot id: A0A0K2NYZ4
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.

1159554:AFK67 RS11620
gene id: 1159554:AFK67_RS11620
uniprot id: A0A0K2P2T1
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

1159554:AFK67 RS12220
gene id: 1159554:AFK67_RS12220
uniprot id: A0A0K2P334
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

1159554:AFK67 RS14440
gene id: 1159554:AFK67_RS14440
uniprot id: A0A0K2P496
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadJ) and two beta chains (FadI).
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the central section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

1159554:AFK67 RS02020
gene id: 1159554:AFK67_RS02020
uniprot id: A0A0K2NYE8
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1159554:AFK67 RS21170
gene id: 1159554:AFK67_RS21170
uniprot id: A0A0K2P8B7
names: Subcellular Location Annotation
messages: Cell inner membrane

1159554:AFK67 RS03775
gene id: 1159554:AFK67_RS03775
uniprot id: A0A0K2NYL1
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1159554:AFK67 RS05905
gene id: 1159554:AFK67_RS05905
uniprot id: A0A0K2P0F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1159554:AFK67 RS02240
gene id: 1159554:AFK67_RS02240
uniprot id: A0A0K2NXZ2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1159554:AFK67 RS03825
gene id: 1159554:AFK67_RS03825
uniprot id: A0A0K2NZB2
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

1159554:AFK67 RS06340
gene id: 1159554:AFK67_RS06340
uniprot id: A0A0K2P048
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1159554:AFK67 RS13660
gene id: 1159554:AFK67_RS13660
uniprot id: A0A0K2P3W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1159554:AFK67 RS00970
gene id: 1159554:AFK67_RS00970
uniprot id: A0A0K2NXS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1159554:AFK67 RS04250
gene id: 1159554:AFK67_RS04250
uniprot id: A0A0K2NZ05
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1159554:AFK67 RS18170
gene id: 1159554:AFK67_RS18170
uniprot id: A0A0K2P6Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1159554:AFK67 RS09710
gene id: 1159554:AFK67_RS09710
uniprot id: A0A0K2P1W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1159554:AFK67 RS09315
gene id: 1159554:AFK67_RS09315
uniprot id: A0A0K2P2A5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1159554:AFK67 RS11225
gene id: 1159554:AFK67_RS11225
uniprot id: A0A0K2P2R2
names: Similarity
messages: Belongs to the UPF0162 family.

1159554:AFK67 RS20245
gene id: 1159554:AFK67_RS20245
uniprot id: A0A0K2P7I2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1159554:AFK67 RS05080
gene id: 1159554:AFK67_RS05080
uniprot id: A0A0K2NZA3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1159554:AFK67 RS01860
gene id: 1159554:AFK67_RS01860
uniprot id: A0A0K2NXU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1159554:AFK67 RS07020
gene id: 1159554:AFK67_RS07020
uniprot id: A0A0K2P0B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

1159554:AFK67 RS13695
gene id: 1159554:AFK67_RS13695
uniprot id: A0A0K2P412
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1159554:AFK67 RS20410
gene id: 1159554:AFK67_RS20410
uniprot id: A0A0K2P7K5
names: Function
names: Similarity
names: Subunit
messages: A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis.
messages: Belongs to the YihI family.
messages: Interacts with Der.

1159554:AFK67 RS07420
gene id: 1159554:AFK67_RS07420
uniprot id: A0A0K2P1C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MatP family.
messages: Cytoplasm
messages: Homodimer.
messages: Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.

1159554:AFK67 RS20655
gene id: 1159554:AFK67_RS20655
uniprot id: A0A0K2P832
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1159554:AFK67 RS01660
gene id: 1159554:AFK67_RS01660
uniprot id: A0A0K2NXK6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1159554:AFK67 RS07015
gene id: 1159554:AFK67_RS07015
uniprot id: A0A0K2P0G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS06895
gene id: 1159554:AFK67_RS06895
uniprot id: A0A0K2P0B7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1159554:AFK67 RS09125
gene id: 1159554:AFK67_RS09125
uniprot id: A0A0K2P1K9
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.
messages: Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters.

1159554:AFK67 RS10040
gene id: 1159554:AFK67_RS10040
uniprot id: A0A0K2P252
names: Similarity
messages: Belongs to the PhzF family.

1159554:AFK67 RS05300
gene id: 1159554:AFK67_RS05300
uniprot id: A0A0K2NZG9
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1159554:AFK67 RS20940
gene id: 1159554:AFK67_RS20940
uniprot id: A0A0K2P8C1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1159554:AFK67 RS11160
gene id: 1159554:AFK67_RS11160
uniprot id: A0A0K2P2J4
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

1159554:AFK67 RS20160
gene id: 1159554:AFK67_RS20160
uniprot id: A0A0K2P7B8
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS15610
gene id: 1159554:AFK67_RS15610
uniprot id: A0A0K2P4W2
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

1159554:AFK67 RS20420
gene id: 1159554:AFK67_RS20420
uniprot id: A0A0K2P7J9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1159554:AFK67 RS18280
gene id: 1159554:AFK67_RS18280
uniprot id: A0A0K2P6G6
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Enables the cell to use acetate during aerobic growth to generate energy via the TCA cycle, and biosynthetic compounds via the glyoxylate shunt. Acetylates CheY, the response regulator involved in flagellar movement and chemotaxis.

1159554:AFK67 RS14005
gene id: 1159554:AFK67_RS14005
uniprot id: A0A0K2P464
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RcsD family.
messages: Cell inner membrane
messages: Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB.
messages: Interacts with RcsC and RcsB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylated by RcsC.

1159554:AFK67 RS13640
gene id: 1159554:AFK67_RS13640
uniprot id: A0A0K2P403
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxT phosphotransferase family.
messages: Cell inner membrane
messages: Involved in the modification of the lipid A domain of lipopolysaccharides (LPS). Transfers a phosphate group from undecaprenyl pyrophosphate (C55-PP) to lipid A to form lipid A 1-diphosphate. Contributes to the recycling of undecaprenyl phosphate (C55-P).

1159554:AFK67 RS13235
gene id: 1159554:AFK67_RS13235
uniprot id: A0A0K2P4D9
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

1159554:AFK67 RS10390
gene id: 1159554:AFK67_RS10390
uniprot id: A0A0K2P2X3
names: Similarity
messages: Belongs to the FrmR/RcnR family.

1159554:AFK67 RS18670
gene id: 1159554:AFK67_RS18670
uniprot id: A0A0K2P6H7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1159554:AFK67 RS14475
gene id: 1159554:AFK67_RS14475
uniprot id: A0A0K2P4F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

1159554:AFK67 RS14035
gene id: 1159554:AFK67_RS14035
uniprot id: A0A0K2P4R6
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

1159554:AFK67 RS07830
gene id: 1159554:AFK67_RS07830
uniprot id: A0A0K2P1J0
names: Similarity
messages: Belongs to the UPF0502 family.

1159554:AFK67 RS19375
gene id: 1159554:AFK67_RS19375
uniprot id: A0A0K2P6W7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS20810
gene id: 1159554:AFK67_RS20810
uniprot id: A0A0K2P862
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS04265
gene id: 1159554:AFK67_RS04265
uniprot id: A0A0K2NZ14
names: Similarity
messages: Belongs to the YkuD family.

1159554:AFK67 RS19620
gene id: 1159554:AFK67_RS19620
uniprot id: A0A0K2P7N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein B family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS21130
gene id: 1159554:AFK67_RS21130
uniprot id: A0A0K2P8Z2
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS16570
gene id: 1159554:AFK67_RS16570
uniprot id: A0A0K2P5I1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Xni family.
messages: Binds 1 K(+) per subunit. The potassium ion strongly increases the affinity for DNA.
messages: Binds 2 Mg(2+) per subunit. Only one magnesium ion has a direct interaction with the protein, the other interactions are indirect.
messages: Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.

1159554:AFK67 RS05040
gene id: 1159554:AFK67_RS05040
uniprot id: A0A0K2NZG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

1159554:AFK67 RS14300
gene id: 1159554:AFK67_RS14300
uniprot id: A0A0K2P4V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS14710
gene id: 1159554:AFK67_RS14710
uniprot id: A0A0K2P533
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CysZ family.
messages: Cell inner membrane
messages: High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway.

1159554:AFK67 RS13120
gene id: 1159554:AFK67_RS13120
uniprot id: M9NJR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1159554:AFK67 RS03165
gene id: 1159554:AFK67_RS03165
uniprot id: A0A0K2NYG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS03940
gene id: 1159554:AFK67_RS03940
uniprot id: A0A0K2NYP3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1159554:AFK67 RS00905
gene id: 1159554:AFK67_RS00905
uniprot id: A0A0K2NXR7
names: Caution
names: Function
names: Similarity
messages: Belongs to the rhamnulokinase family.
messages: Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1159554:AFK67 RS18535
gene id: 1159554:AFK67_RS18535
uniprot id: A0A0K2P6F6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1159554:AFK67 RS17465
gene id: 1159554:AFK67_RS17465
uniprot id: A0A0K2P5X4
names: Subcellular Location Annotation
messages: Cytoplasm

1159554:AFK67 RS07370
gene id: 1159554:AFK67_RS07370
uniprot id: A0A0K2P0P9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1159554:AFK67 RS02880
gene id: 1159554:AFK67_RS02880
uniprot id: A0A0K2NYA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1159554:AFK67 RS13565
gene id: 1159554:AFK67_RS13565
uniprot id: A0A0K2P7V5
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS17000
gene id: 1159554:AFK67_RS17000
uniprot id: A0A0K2P5L0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

1159554:AFK67 RS15970
gene id: 1159554:AFK67_RS15970
uniprot id: A0A0K2P526
names: Similarity
messages: Belongs to the peptidase S14 family.

1159554:AFK67 RS09490
gene id: 1159554:AFK67_RS09490
uniprot id: A0A0K2P2E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1159554:AFK67 RS18380
gene id: 1159554:AFK67_RS18380
uniprot id: A0A0K2P6E3
names: Similarity
messages: Belongs to the UPF0047 family.

1159554:AFK67 RS01035
gene id: 1159554:AFK67_RS01035
uniprot id: A0A0K2NXA1
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1159554:AFK67 RS18460
gene id: 1159554:AFK67_RS18460
uniprot id: A0A0K2P6F7
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Cell membrane
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

1159554:AFK67 RS01420
gene id: 1159554:AFK67_RS01420
uniprot id: A0A0K2NXK7
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1159554:AFK67 RS08575
gene id: 1159554:AFK67_RS08575
uniprot id: A0A0K2P153
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1159554:AFK67 RS10195
gene id: 1159554:AFK67_RS10195
uniprot id: A0A0K2P206
names: Similarity
messages: Belongs to the UPF0482 family.

1159554:AFK67 RS12540
gene id: 1159554:AFK67_RS12540
uniprot id: A0A0K2P424
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane
messages: Responsible for the transport of C4-dicarboxylates.

1159554:AFK67 RS03010
gene id: 1159554:AFK67_RS03010
uniprot id: A0A0K2NYC6
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

1159554:AFK67 RS15405
gene id: 1159554:AFK67_RS15405
uniprot id: A0A0K2P4X0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. SrmB subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity.
messages: Interacts with the 50S ribosomal subunit.

1159554:AFK67 RS06845
gene id: 1159554:AFK67_RS06845
uniprot id: A0A0K2P0E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS07530
gene id: 1159554:AFK67_RS07530
uniprot id: A0A0K2P0T0
names: Similarity
messages: Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family.

1159554:AFK67 RS08700
gene id: 1159554:AFK67_RS08700
uniprot id: A0A0K2P1D1
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1159554:AFK67 RS15505
gene id: 1159554:AFK67_RS15505
uniprot id: A0A0K2P4Y4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1159554:AFK67 RS10285
gene id: 1159554:AFK67_RS10285
uniprot id: A0A0K2P297
names: Similarity
messages: Belongs to the peptidase S1B family.

1159554:AFK67 RS08120
gene id: 1159554:AFK67_RS08120
uniprot id: A0A0K2P0Z6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

1159554:AFK67 RS17210
gene id: 1159554:AFK67_RS17210
uniprot id: A0A0K2P5V4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1159554:AFK67 RS16985
gene id: 1159554:AFK67_RS16985
uniprot id: A0A0K2P5R0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LysR transcriptional regulatory family.
messages: Controls the transcription of genes involved in arginine and lysine metabolism.
messages: Homodimer.

1159554:AFK67 RS20590
gene id: 1159554:AFK67_RS20590
uniprot id: A0A0K2P8P5
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS20050
gene id: 1159554:AFK67_RS20050
uniprot id: A0A0K2P7C4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

1159554:AFK67 RS04055
gene id: 1159554:AFK67_RS04055
uniprot id: A0A0K2NYT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1159554:AFK67 RS01535
gene id: 1159554:AFK67_RS01535
uniprot id: A0A0K2NXL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).

1159554:AFK67 RS19390
gene id: 1159554:AFK67_RS19390
uniprot id: A0A0K2P6Z5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PanZ/PanM family.
messages: Controls both the activation and catalytic activity of PanD in a coenzyme A (CoA)-dependent fashion.
messages: Interacts with PanD in the presence of CoA.

1159554:AFK67 RS00375
gene id: 1159554:AFK67_RS00375
uniprot id: A0A0K2NWZ2
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS05875
gene id: 1159554:AFK67_RS05875
uniprot id: A0A0K2NZW2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.

1159554:AFK67 RS12595
gene id: 1159554:AFK67_RS12595
uniprot id: A0A0K2P3F5
names: Subcellular Location Annotation
messages: Cytoplasm

1159554:AFK67 RS09555
gene id: 1159554:AFK67_RS09555
uniprot id: A0A0K2P7R4
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1159554:AFK67 RS00895
gene id: 1159554:AFK67_RS00895
uniprot id: A0A0K2NX75
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aldolase class II family. RhaD subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.
messages: Cytoplasm
messages: Homotetramer.

1159554:AFK67 RS14490
gene id: 1159554:AFK67_RS14490
uniprot id: A0A0K2P4A4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1159554:AFK67 RS03565
gene id: 1159554:AFK67_RS03565
uniprot id: A0A0K2NYN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1159554:AFK67 RS18760
gene id: 1159554:AFK67_RS18760
uniprot id: A0A0K2P6P9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1159554:AFK67 RS04960
gene id: 1159554:AFK67_RS04960
uniprot id: A0A0K2NZA6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1159554:AFK67 RS14330
gene id: 1159554:AFK67_RS14330
uniprot id: A0A0K2P4B9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1159554:AFK67 RS16550
gene id: 1159554:AFK67_RS16550
uniprot id: A0A0K2P626
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

1159554:AFK67 RS03215
gene id: 1159554:AFK67_RS03215
uniprot id: A0A0K2NY94
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1159554:AFK67 RS03220
gene id: 1159554:AFK67_RS03220
uniprot id: A0A0K2NYC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TrpR family.
messages: Cytoplasm
messages: Homodimer.
messages: This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region.

1159554:AFK67 RS20300
gene id: 1159554:AFK67_RS20300
uniprot id: A0A0K2P831
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1159554:AFK67 RS05530
gene id: 1159554:AFK67_RS05530
uniprot id: A0A0K2NZQ2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1159554:AFK67 RS18185
gene id: 1159554:AFK67_RS18185
uniprot id: A0A0K2P6A9
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

1159554:AFK67 RS17940
gene id: 1159554:AFK67_RS17940
uniprot id: A0A0K2P6A6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1159554:AFK67 RS03645
gene id: 1159554:AFK67_RS03645
uniprot id: A0A0K2NYI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1159554:AFK67 RS20355
gene id: 1159554:AFK67_RS20355
uniprot id: A0A0K2P841
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1159554:AFK67 RS16475
gene id: 1159554:AFK67_RS16475
uniprot id: A0A0K2P612
names: Function
names: Similarity
messages: Belongs to the NanE family.
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

1159554:AFK67 RS20130
gene id: 1159554:AFK67_RS20130
uniprot id: A0A0K2P7A6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1159554:AFK67 RS07375
gene id: 1159554:AFK67_RS07375
uniprot id: A0A0K2P7T8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapC family.
messages: Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.
messages: Cytoplasm
messages: Interacts directly with FtsZ.

1159554:AFK67 RS18155
gene id: 1159554:AFK67_RS18155
uniprot id: A0A0K2P690
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

1159554:AFK67 RS11425
gene id: 1159554:AFK67_RS11425
uniprot id: A0A0K2P7Y8
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS00285
gene id: 1159554:AFK67_RS00285
uniprot id: A0A0K2NXH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1159554:AFK67 RS12655
gene id: 1159554:AFK67_RS12655
uniprot id: A0A0K2P3I5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.
messages: Catalyzes the alpha,beta-elimination reaction of D-cysteine and of several D-cysteine derivatives. It could be a defense mechanism against D-cysteine.
messages: Homodimer.

1159554:AFK67 RS10810
gene id: 1159554:AFK67_RS10810
uniprot id: A0A0K2P2C6
names: Similarity
messages: Belongs to the UPF0509 family.

1159554:AFK67 RS01880
gene id: 1159554:AFK67_RS01880
uniprot id: A0A0K2NXQ1
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1159554:AFK67 RS11735
gene id: 1159554:AFK67_RS11735
uniprot id: A0A0K2P3I6
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS17120
gene id: 1159554:AFK67_RS17120
uniprot id: A0A0K2P5S4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1159554:AFK67 RS17975
gene id: 1159554:AFK67_RS17975
uniprot id: A0A0K2P696
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1159554:AFK67 RS04010
gene id: 1159554:AFK67_RS04010
uniprot id: A0A0K2NZF6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1159554:AFK67 RS15075
gene id: 1159554:AFK67_RS15075
uniprot id: A0A0K2P4L5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1159554:AFK67 RS05045
gene id: 1159554:AFK67_RS05045
uniprot id: A0A0K2P015
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

1159554:AFK67 RS12780
gene id: 1159554:AFK67_RS12780
uniprot id: A0A0K2P3F7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Flagellar protein that affects chemotactic events.
messages: Membrane

1159554:AFK67 RS08595
gene id: 1159554:AFK67_RS08595
uniprot id: A0A0K2P1B1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1159554:AFK67 RS14570
gene id: 1159554:AFK67_RS14570
uniprot id: A0A0K2P4B6
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

1159554:AFK67 RS15795
gene id: 1159554:AFK67_RS15795
uniprot id: A0A0K2P8K9
names: Function
names: Similarity
messages: Belongs to the phage GPA family.
messages: Possible endonuclease which induces a single-strand cut and initiates DNA replication.

1159554:AFK67 RS01000
gene id: 1159554:AFK67_RS01000
uniprot id: A0A0K2NXC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsN family.
messages: Cell inner membrane
messages: Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases.
messages: Interacts with FtsA via its N-terminal cytoplasmic domain.

1159554:AFK67 RS02680
gene id: 1159554:AFK67_RS02680
uniprot id: A0A0K2NYQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1159554:AFK67 RS18880
gene id: 1159554:AFK67_RS18880
uniprot id: A0A0K2P6L6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DsrF/TusC family.
messages: Cytoplasm
messages: Heterohexamer, formed by a dimer of trimers. The hexameric TusBCD complex contains 2 copies each of TusB, TusC and TusD. The TusBCD complex interacts with TusE.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.

1159554:AFK67 RS19130
gene id: 1159554:AFK67_RS19130
uniprot id: A0A0K2P6U6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

1159554:AFK67 RS16205
gene id: 1159554:AFK67_RS16205
uniprot id: A0A0K2P5W9
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS16430
gene id: 1159554:AFK67_RS16430
uniprot id: A0A0K2P5D8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1159554:AFK67 RS07255
gene id: 1159554:AFK67_RS07255
uniprot id: A0A0K2P0J2
names: Similarity
messages: Belongs to the UPF0434 family.

1159554:AFK67 RS15205
gene id: 1159554:AFK67_RS15205
uniprot id: A0A0K2P4P2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 2 iron ions per dimer. The dimer may bind additional iron ions.
messages: Homodimer; may form tetramers and higher multimers.
messages: Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB.

1159554:AFK67 RS21150
gene id: 1159554:AFK67_RS21150
uniprot id: A0A0K2P8B9
names: Function
names: Subunit
messages: Homodimer.
messages: Required for resistance to the phenazine antibiotic.

1159554:AFK67 RS19595
gene id: 1159554:AFK67_RS19595
uniprot id: A0A0K2P7N4
names: Similarity
messages: Belongs to the peptidase C40 family.

1159554:AFK67 RS16665
gene id: 1159554:AFK67_RS16665
uniprot id: A0A0K2P5I0
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS19060
gene id: 1159554:AFK67_RS19060
uniprot id: A0A0K2P6R1
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1159554:AFK67 RS19215
gene id: 1159554:AFK67_RS19215
uniprot id: A0A0K2P6U0
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activated by ATP and maltotriose, which are both required for DNA binding.
messages: Belongs to the MalT family.
messages: Monomer in solution. Oligomerizes to an active state in the presence of the positive effectors ATP and maltotriose.
messages: Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.

1159554:AFK67 RS03160
gene id: 1159554:AFK67_RS03160
uniprot id: A0A0K2NYB8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1159554:AFK67 RS18755
gene id: 1159554:AFK67_RS18755
uniprot id: A0A0K2P6K5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1159554:AFK67 RS01480
gene id: 1159554:AFK67_RS01480
uniprot id: A0A0K2NY37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

1159554:AFK67 RS03875
gene id: 1159554:AFK67_RS03875
uniprot id: A0A0K2NZC6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1159554:AFK67 RS07350
gene id: 1159554:AFK67_RS07350
uniprot id: A0A0K2P0I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1159554:AFK67 RS11575
gene id: 1159554:AFK67_RS11575
uniprot id: A0A0K2P3F2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: Multifunctional regulator of fatty acid metabolism.

1159554:AFK67 RS01475
gene id: 1159554:AFK67_RS01475
uniprot id: A0A0K2NXL7
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1159554:AFK67 RS11140
gene id: 1159554:AFK67_RS11140
uniprot id: A0A0K2P2K0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS14220
gene id: 1159554:AFK67_RS14220
uniprot id: A0A0K2P4A5
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS08355
gene id: 1159554:AFK67_RS08355
uniprot id: A0A0K2P167
names: Function
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.

1159554:AFK67 RS15500
gene id: 1159554:AFK67_RS15500
uniprot id: A0A0K2P5K4
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1159554:AFK67 RS10240
gene id: 1159554:AFK67_RS10240
uniprot id: A0A0K2P2U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1159554:AFK67 RS10010
gene id: 1159554:AFK67_RS10010
uniprot id: A0A0K2P1Z7
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

1159554:AFK67 RS13170
gene id: 1159554:AFK67_RS13170
uniprot id: M9NHX8
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1159554:AFK67 RS16645
gene id: 1159554:AFK67_RS16645
uniprot id: A0A0K2P5E4
names: Function
names: Similarity
messages: Belongs to the peptidase M16 family.
messages: Endopeptidase that degrades small peptides of less than 7 kDa, such as glucagon and insulin.

1159554:AFK67 RS14725
gene id: 1159554:AFK67_RS14725
uniprot id: A0A0K2P4E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1159554:AFK67 RS12645
gene id: 1159554:AFK67_RS12645
uniprot id: A0A0K2P3C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS07465
gene id: 1159554:AFK67_RS07465
uniprot id: A0A0K2P7P7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HspQ family.
messages: Cytoplasm
messages: Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress.

1159554:AFK67 RS10280
gene id: 1159554:AFK67_RS10280
uniprot id: A0A0K2P245
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

1159554:AFK67 RS02995
gene id: 1159554:AFK67_RS02995
uniprot id: A0A0K2NYD7
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1159554:AFK67 RS15055
gene id: 1159554:AFK67_RS15055
uniprot id: A0A0K2P4K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GppA/Ppx family.
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS19155
gene id: 1159554:AFK67_RS19155
uniprot id: A0A0K2P6U9
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

1159554:AFK67 RS20040
gene id: 1159554:AFK67_RS20040
uniprot id: A0A0K2P7E6
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Member of a two-component regulatory system.

1159554:AFK67 RS05490
gene id: 1159554:AFK67_RS05490
uniprot id: A0A0K2NZN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1159554:AFK67 RS16310
gene id: 1159554:AFK67_RS16310
uniprot id: A0A0K2P823
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS12670
gene id: 1159554:AFK67_RS12670
uniprot id: A0A0K2P3D0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

1159554:AFK67 RS10215
gene id: 1159554:AFK67_RS10215
uniprot id: A0A0K2P270
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1159554:AFK67 RS13240
gene id: 1159554:AFK67_RS13240
uniprot id: A0A0K2P3R5
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1159554:AFK67 RS14320
gene id: 1159554:AFK67_RS14320
uniprot id: A0A0K2P4C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

1159554:AFK67 RS06215
gene id: 1159554:AFK67_RS06215
uniprot id: A0A0K2P021
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Catalyzes both the uptake and excretion of putrescine. The uptake of putrescine is dependent on the membrane potential and the excretion involves putrescine-ornithine antiporter activity.
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS05850
gene id: 1159554:AFK67_RS05850
uniprot id: A0A0K2NZV7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Monomer.

1159554:AFK67 RS03400
gene id: 1159554:AFK67_RS03400
uniprot id: A0A0K2NYK9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1159554:AFK67 RS01260
gene id: 1159554:AFK67_RS01260
uniprot id: A0A0K2NXG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. WecC subfamily.
messages: Catalyzes the four-electron oxidation of UDP-N-acetyl-D-mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N-acetylmannosaminuronic acid (UDP-ManNAcA).
messages: Homodimer.

1159554:AFK67 RS15605
gene id: 1159554:AFK67_RS15605
uniprot id: A0A0K2P502
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1159554:AFK67 RS18040
gene id: 1159554:AFK67_RS18040
uniprot id: A0A0K2P6C6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1159554:AFK67 RS07565
gene id: 1159554:AFK67_RS07565
uniprot id: A0A0K2P0T1
names: Function
names: Similarity
messages: Belongs to the nitroreductase family. HadB/RutE subfamily.
messages: May reduce toxic product malonic semialdehyde to 3-hydroxypropionic acid, which is excreted.

1159554:AFK67 RS19730
gene id: 1159554:AFK67_RS19730
uniprot id: A0A0K2P762
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose.
messages: Cell inner membrane

1159554:AFK67 RS04875
gene id: 1159554:AFK67_RS04875
uniprot id: A0A0K2NZ62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1159554:AFK67 RS14965
gene id: 1159554:AFK67_RS14965
uniprot id: A0A0K2P590
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0370 family.
messages: Cell membrane

1159554:AFK67 RS11465
gene id: 1159554:AFK67_RS11465
uniprot id: A0A0K2P3D5
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1159554:AFK67 RS18660
gene id: 1159554:AFK67_RS18660
uniprot id: A0A0K2P776
names: Similarity
messages: Belongs to the Smg family.

1159554:AFK67 RS01485
gene id: 1159554:AFK67_RS01485
uniprot id: A0A0K2NXK1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1159554:AFK67 RS04530
gene id: 1159554:AFK67_RS04530
uniprot id: A0A0K2NZ65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Gfo/Idh/MocA family.
messages: Homotetramer.
messages: Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).

1159554:AFK67 RS05945
gene id: 1159554:AFK67_RS05945
uniprot id: A0A0K2NZT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the lipid A palmitoyltransferase family.
messages: Cell outer membrane
messages: Homodimer.
messages: Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors.

1159554:AFK67 RS05370
gene id: 1159554:AFK67_RS05370
uniprot id: A0A0K2NZF7
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1159554:AFK67 RS10770
gene id: 1159554:AFK67_RS10770
uniprot id: A0A0K2P2I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS17860
gene id: 1159554:AFK67_RS17860
uniprot id: A0A0K2P647
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS05810
gene id: 1159554:AFK67_RS05810
uniprot id: A0A0K2NZN6
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
messages: Homodimer.

1159554:AFK67 RS01280
gene id: 1159554:AFK67_RS01280
uniprot id: A0A0K2NXZ4
names: Function
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.
messages: Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D-galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D-Glc4O) and L-glutamate.

1159554:AFK67 RS10350
gene id: 1159554:AFK67_RS10350
uniprot id: A0A0K2P236
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.
messages: Probably involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans (OPGs).

1159554:AFK67 RS12290
gene id: 1159554:AFK67_RS12290
uniprot id: A0A0K2P391
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1159554:AFK67 RS10190
gene id: 1159554:AFK67_RS10190
uniprot id: A0A0K2P7S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

1159554:AFK67 RS17270
gene id: 1159554:AFK67_RS17270
uniprot id: A0A0K2P5V2
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

1159554:AFK67 RS10975
gene id: 1159554:AFK67_RS10975
uniprot id: A0A0K2P2L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1159554:AFK67 RS03725
gene id: 1159554:AFK67_RS03725
uniprot id: A0A0K2NYN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS07025
gene id: 1159554:AFK67_RS07025
uniprot id: A0A0K2P0E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

1159554:AFK67 RS17335
gene id: 1159554:AFK67_RS17335
uniprot id: A0A0K2P5X8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. TDG/mug family.
messages: Binds DNA as a monomer.
messages: Cytoplasm
messages: Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA. It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base. The complementary strand guanine functions in substrate recognition. Required for DNA damage lesion repair in stationary-phase cells.

1159554:AFK67 RS18765
gene id: 1159554:AFK67_RS18765
uniprot id: A0A0K2P792
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1159554:AFK67 RS09175
gene id: 1159554:AFK67_RS09175
uniprot id: A0A0K2P279
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1159554:AFK67 RS01170
gene id: 1159554:AFK67_RS01170
uniprot id: A0A0K2NXC2
names: Similarity
messages: Belongs to the UPF0438 family.

1159554:AFK67 RS02660
gene id: 1159554:AFK67_RS02660
uniprot id: A0A0K2NY66
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1159554:AFK67 RS03270
gene id: 1159554:AFK67_RS03270
uniprot id: A0A0K2NYD8
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

1159554:AFK67 RS18800
gene id: 1159554:AFK67_RS18800
uniprot id: A0A0K2P6K1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1159554:AFK67 RS03650
gene id: 1159554:AFK67_RS03650
uniprot id: A0A0K2NYL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

1159554:AFK67 RS06740
gene id: 1159554:AFK67_RS06740
uniprot id: A0A0K2P0C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS04800
gene id: 1159554:AFK67_RS04800
uniprot id: A0A0K2NZ76
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS17320
gene id: 1159554:AFK67_RS17320
uniprot id: A0A0K2P5W2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1159554:AFK67 RS01270
gene id: 1159554:AFK67_RS01270
uniprot id: A0A0K2NXE3
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1159554:AFK67 RS05085
gene id: 1159554:AFK67_RS05085
uniprot id: A0A0K2NZD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1159554:AFK67 RS20120
gene id: 1159554:AFK67_RS20120
uniprot id: A0A0K2P7Z2
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

1159554:AFK67 RS10445
gene id: 1159554:AFK67_RS10445
uniprot id: A0A0K2P2Y2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1159554:AFK67 RS11415
gene id: 1159554:AFK67_RS11415
uniprot id: A0A0K2P2S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPS (TC 1.B.20) family.
messages: Cell outer membrane
messages: Membrane

1159554:AFK67 RS19015
gene id: 1159554:AFK67_RS19015
uniprot id: A0A0K2P6U5
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

1159554:AFK67 RS00065
gene id: 1159554:AFK67_RS00065
uniprot id: A0A0K2NWY0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

1159554:AFK67 RS12300
gene id: 1159554:AFK67_RS12300
uniprot id: A0A0K2P363
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1159554:AFK67 RS18265
gene id: 1159554:AFK67_RS18265
uniprot id: A0A0K2P6A8
names: Similarity
messages: Belongs to the heat shock protein 90 family.

1159554:AFK67 RS07940
gene id: 1159554:AFK67_RS07940
uniprot id: A0A0K2P0T8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1159554:AFK67 RS18450
gene id: 1159554:AFK67_RS18450
uniprot id: A0A0K2P6I0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1159554:AFK67 RS16395
gene id: 1159554:AFK67_RS16395
uniprot id: A0A0K2P5E8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

1159554:AFK67 RS17740
gene id: 1159554:AFK67_RS17740
uniprot id: A0A0K2P6Q1
names: Similarity
messages: Belongs to the UPF0307 family.

1159554:AFK67 RS02615
gene id: 1159554:AFK67_RS02615
uniprot id: A0A0K2NXZ1
names: Similarity
messages: Belongs to the carbamate kinase family.

1159554:AFK67 RS06985
gene id: 1159554:AFK67_RS06985
uniprot id: A0A0K2P122
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmC subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA.

1159554:AFK67 RS07100
gene id: 1159554:AFK67_RS07100
uniprot id: A0A0K2P0H2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1159554:AFK67 RS04145
gene id: 1159554:AFK67_RS04145
uniprot id: A0A0K2NYZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RcsF family.
messages: Cell outer membrane
messages: Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects.

1159554:AFK67 RS14500
gene id: 1159554:AFK67_RS14500
uniprot id: A0A0K2P4F6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1159554:AFK67 RS14830
gene id: 1159554:AFK67_RS14830
uniprot id: A0A0K2P4G3
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

1159554:AFK67 RS20390
gene id: 1159554:AFK67_RS20390
uniprot id: A0A0K2P7F9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

1159554:AFK67 RS14755
gene id: 1159554:AFK67_RS14755
uniprot id: A0A0K2P4J6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1159554:AFK67 RS02330
gene id: 1159554:AFK67_RS02330
uniprot id: A0A0K2NYJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiV subfamily.
messages: Forms an heterodimer with UbiU.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiU, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

1159554:AFK67 RS03305
gene id: 1159554:AFK67_RS03305
uniprot id: A0A0K2NZ07
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS06730
gene id: 1159554:AFK67_RS06730
uniprot id: A0A0K2P057
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1159554:AFK67 RS10940
gene id: 1159554:AFK67_RS10940
uniprot id: A0A0K2P2F5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1159554:AFK67 RS00830
gene id: 1159554:AFK67_RS00830
uniprot id: A0A0K2NX20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

1159554:AFK67 RS20265
gene id: 1159554:AFK67_RS20265
uniprot id: A0A0K2P7D9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1159554:AFK67 RS14350
gene id: 1159554:AFK67_RS14350
uniprot id: A0A0K2P7W4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1159554:AFK67 RS01710
gene id: 1159554:AFK67_RS01710
uniprot id: A0A0K2NXN3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

1159554:AFK67 RS00995
gene id: 1159554:AFK67_RS00995
uniprot id: A0A0K2NXT4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1159554:AFK67 RS18975
gene id: 1159554:AFK67_RS18975
uniprot id: A0A0K2P6S0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in both the arginine and lysine biosynthetic pathways.

1159554:AFK67 RS00330
gene id: 1159554:AFK67_RS00330
uniprot id: A0A0K2NX30
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1159554:AFK67 RS20280
gene id: 1159554:AFK67_RS20280
uniprot id: A0A0K2P7H2
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigB subfamily.
messages: Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.

1159554:AFK67 RS15035
gene id: 1159554:AFK67_RS15035
uniprot id: A0A0K2P4P8
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1159554:AFK67 RS07470
gene id: 1159554:AFK67_RS07470
uniprot id: A0A0K2P0M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmI family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA.

1159554:AFK67 RS04020
gene id: 1159554:AFK67_RS04020
uniprot id: A0A0K2P7S7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Homodimer.

1159554:AFK67 RS08710
gene id: 1159554:AFK67_RS08710
uniprot id: A0A0K2P1A2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L-selenocysteine. Selenocysteine lyase activity is however unsure in vivo.
messages: Cytoplasm
messages: Homodimer. Interacts with SufE and the SufBCD complex composed of SufB, SufC and SufD. The interaction with SufE is required to mediate the direct transfer of the sulfur atom from the S-sulfanylcysteine.

1159554:AFK67 RS03730
gene id: 1159554:AFK67_RS03730
uniprot id: A0A0K2NYS7
names: Similarity
messages: Belongs to the GSP E family.

1159554:AFK67 RS06560
gene id: 1159554:AFK67_RS06560
uniprot id: A0A0K2P049
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1159554:AFK67 RS04375
gene id: 1159554:AFK67_RS04375
uniprot id: A0A0K2NZM7
names: Function
names: Similarity
messages: Belongs to the peptidase M16 family.
messages: Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. It is thought that this protein is a protease that cleaves peptides bond in a small peptide (gene pqqA), providing the glutamate and tyrosine residues which are necessary for the synthesis of PQQ.

1159554:AFK67 RS12340
gene id: 1159554:AFK67_RS12340
uniprot id: A0A0K2P397
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1159554:AFK67 RS12370
gene id: 1159554:AFK67_RS12370
uniprot id: A0A0K2P367
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1159554:AFK67 RS18810
gene id: 1159554:AFK67_RS18810
uniprot id: A0A0K2P6Q9
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1159554:AFK67 RS03250
gene id: 1159554:AFK67_RS03250
uniprot id: A0A0K2NYI0
names: Subcellular Location Annotation
messages: Cell inner membrane

1159554:AFK67 RS14230
gene id: 1159554:AFK67_RS14230
uniprot id: A0A0K2P499
names: Similarity
messages: Belongs to the UPF0304 family.

1159554:AFK67 RS01675
gene id: 1159554:AFK67_RS01675
uniprot id: A0A0K2NXP9
names: Cofactor
messages: Binds 1 Mg(2+) ion per trimer.

1159554:AFK67 RS15250
gene id: 1159554:AFK67_RS15250
uniprot id: A0A0K2P4U3
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS12385
gene id: 1159554:AFK67_RS12385
uniprot id: A0A0K2P3X5
names: Similarity
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.

1159554:AFK67 RS13090
gene id: 1159554:AFK67_RS13090
uniprot id: A0A0K2P3N5
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.

1159554:AFK67 RS09385
gene id: 1159554:AFK67_RS09385
uniprot id: A0A0K2P1R9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1159554:AFK67 RS14985
gene id: 1159554:AFK67_RS14985
uniprot id: A0A0K2P4P1
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1159554:AFK67 RS00315
gene id: 1159554:AFK67_RS00315
uniprot id: A0A0K2NX03
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the dehydration of D-galactonate to 2-keto-3-deoxy-D-galactonate.
messages: Reaction proceeds via an anti dehydration.

1159554:AFK67 RS15080
gene id: 1159554:AFK67_RS15080
uniprot id: A0A0K2P4L3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

1159554:AFK67 RS08865
gene id: 1159554:AFK67_RS08865
uniprot id: A0A0K2P1I0
names: Function
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.

1159554:AFK67 RS20170
gene id: 1159554:AFK67_RS20170
uniprot id: A0A0K2P803
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

1159554:AFK67 RS02360
gene id: 1159554:AFK67_RS02360
uniprot id: A0A0K2NY11
names: Similarity
messages: Belongs to the peptidase C56 family.

1159554:AFK67 RS13500
gene id: 1159554:AFK67_RS13500
uniprot id: A0A0K2P3T4
names: Function
names: Similarity
messages: Belongs to the Dus family. DusC subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs.

1159554:AFK67 RS11215
gene id: 1159554:AFK67_RS11215
uniprot id: A0A0K2P2K2
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS08675
gene id: 1159554:AFK67_RS08675
uniprot id: A0A0K2P7U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1159554:AFK67 RS13050
gene id: 1159554:AFK67_RS13050
uniprot id: A0A0K2P7Z1
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

1159554:AFK67 RS12490
gene id: 1159554:AFK67_RS12490
uniprot id: A0A0K2P415
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhD family.
messages: Cytoplasm
messages: Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Homodimer; disulfide-linked. Forms a heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.
messages: The C-terminal region contains a putative helix-turn-helix (HTH) motif, suggesting that this region may bind DNA.

1159554:AFK67 RS16935
gene id: 1159554:AFK67_RS16935
uniprot id: A0A0K2P5Q1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1159554:AFK67 RS08765
gene id: 1159554:AFK67_RS08765
uniprot id: A0A0K2P1G0
names: Similarity
messages: Belongs to the glutamine synthetase family.

1159554:AFK67 RS12235
gene id: 1159554:AFK67_RS12235
uniprot id: A0A0K2P3U2
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1159554:AFK67 RS16600
gene id: 1159554:AFK67_RS16600
uniprot id: A0A0K2P636
names: Similarity
messages: Belongs to the SufE family.

1159554:AFK67 RS16290
gene id: 1159554:AFK67_RS16290
uniprot id: A0A0K2P5B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS07140
gene id: 1159554:AFK67_RS07140
uniprot id: A0A0K2P0K5
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS12830
gene id: 1159554:AFK67_RS12830
uniprot id: A0A0K2P3G7
names: Similarity
messages: Belongs to the DsrB family.

1159554:AFK67 RS13230
gene id: 1159554:AFK67_RS13230
uniprot id: A0A0K2P3T6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Hydrolyzes GDP-mannose.

1159554:AFK67 RS20890
gene id: 1159554:AFK67_RS20890
uniprot id: A0A0K2P8V2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1159554:AFK67 RS18995
gene id: 1159554:AFK67_RS18995
uniprot id: A0A0K2P7D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TsgA family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS12650
gene id: 1159554:AFK67_RS12650
uniprot id: A0A0K2P3D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS15060
gene id: 1159554:AFK67_RS15060
uniprot id: A0A0K2P4Q1
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS21185
gene id: 1159554:AFK67_RS21185
uniprot id: A0A0K2P901
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1159554:AFK67 RS15130
gene id: 1159554:AFK67_RS15130
uniprot id: A0A0K2P4M3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1159554:AFK67 RS19255
gene id: 1159554:AFK67_RS19255
uniprot id: A0A0K2P6Z2
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1159554:AFK67 RS19240
gene id: 1159554:AFK67_RS19240
uniprot id: A0A0K2P6W8
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS06725
gene id: 1159554:AFK67_RS06725
uniprot id: A0A0K2P0B9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 1618 of 23S rRNA.

1159554:AFK67 RS04045
gene id: 1159554:AFK67_RS04045
uniprot id: A0A0K2NYX1
names: Similarity
messages: Belongs to the skp family.

1159554:AFK67 RS18805
gene id: 1159554:AFK67_RS18805
uniprot id: A0A0K2P6L5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1159554:AFK67 RS13560
gene id: 1159554:AFK67_RS13560
uniprot id: A0A0K2P3Z1
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

1159554:AFK67 RS20985
gene id: 1159554:AFK67_RS20985
uniprot id: A0A0K2P890
names: Similarity
messages: Belongs to the IucA/IucC family.

1159554:AFK67 RS06945
gene id: 1159554:AFK67_RS06945
uniprot id: A0A0K2P097
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

1159554:AFK67 RS01970
gene id: 1159554:AFK67_RS01970
uniprot id: A0A0K2NXU2
names: Similarity
messages: Belongs to the barstar family.

1159554:AFK67 RS18015
gene id: 1159554:AFK67_RS18015
uniprot id: A0A0K2P6C1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1159554:AFK67 RS08885
gene id: 1159554:AFK67_RS08885
uniprot id: A0A0K2P1D8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1159554:AFK67 RS20295
gene id: 1159554:AFK67_RS20295
uniprot id: A0A0K2P7J2
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1159554:AFK67 RS05355
gene id: 1159554:AFK67_RS05355
uniprot id: A0A0K2NZM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1159554:AFK67 RS07290
gene id: 1159554:AFK67_RS07290
uniprot id: A0A0K2P1A1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MukF family.
messages: Interacts, and probably forms a ternary complex, with MukE and MukB via its C-terminal region. The complex formation is stimulated by calcium or magnesium. It is required for an interaction between MukE and MukB.
messages: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.
messages: nucleoid

1159554:AFK67 RS10840
gene id: 1159554:AFK67_RS10840
uniprot id: A0A0K2P2E6
names: Similarity
messages: Belongs to the SUI1 family.

1159554:AFK67 RS03585
gene id: 1159554:AFK67_RS03585
uniprot id: A0A0K2NZ59
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1159554:AFK67 RS11755
gene id: 1159554:AFK67_RS11755
uniprot id: A0A0K2P307
names: Subcellular Location Annotation
messages: Cytoplasm

1159554:AFK67 RS19340
gene id: 1159554:AFK67_RS19340
uniprot id: A0A0K2P6Y5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. UgpAE subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).

1159554:AFK67 RS07895
gene id: 1159554:AFK67_RS07895
uniprot id: A0A0K2P0V1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1159554:AFK67 RS04885
gene id: 1159554:AFK67_RS04885
uniprot id: A0A0K2NZE1
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

1159554:AFK67 RS19965
gene id: 1159554:AFK67_RS19965
uniprot id: A0A0K2P7A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.
messages: Membrane

1159554:AFK67 RS10230
gene id: 1159554:AFK67_RS10230
uniprot id: A0A0K2P7R9
names: Function
names: Similarity
messages: Belongs to the TorD/DmsD family. DmsD subfamily.
messages: Required for biogenesis/assembly of DMSO reductase, but not for the interaction of the DmsA signal peptide with the Tat system. May be part of a chaperone cascade complex that facilitates a folding-maturation pathway for the substrate protein.

1159554:AFK67 RS03110
gene id: 1159554:AFK67_RS03110
uniprot id: A0A0K2NYA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1159554:AFK67 RS01095
gene id: 1159554:AFK67_RS01095
uniprot id: A0A0K2NXV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

1159554:AFK67 RS14630
gene id: 1159554:AFK67_RS14630
uniprot id: A0A0K2P519
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

1159554:AFK67 RS02475
gene id: 1159554:AFK67_RS02475
uniprot id: A0A0K2NYM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MzrA family.
messages: Cell inner membrane
messages: Interacts with EnvZ.
messages: Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR.

1159554:AFK67 RS07385
gene id: 1159554:AFK67_RS07385
uniprot id: A0A0K2P0K8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

1159554:AFK67 RS20275
gene id: 1159554:AFK67_RS20275
uniprot id: A0A0K2P824
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1159554:AFK67 RS02390
gene id: 1159554:AFK67_RS02390
uniprot id: A0A0K2P7R6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LpoA family.
messages: Interacts with PBP1a.
messages: Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a).

1159554:AFK67 RS20115
gene id: 1159554:AFK67_RS20115
uniprot id: A0A0K2P7F8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1159554:AFK67 RS17115
gene id: 1159554:AFK67_RS17115
uniprot id: A0A0K2P6B8
names: Similarity
messages: Belongs to the UPF0235 family.

1159554:AFK67 RS14835
gene id: 1159554:AFK67_RS14835
uniprot id: A0A0K2P4L2
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS05065
gene id: 1159554:AFK67_RS05065
uniprot id: A0A0K2NZH2
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS08935
gene id: 1159554:AFK67_RS08935
uniprot id: A0A0K2P1C5
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS12785
gene id: 1159554:AFK67_RS12785
uniprot id: A0A0K2P3K9
names: Function
names: Similarity
messages: Belongs to the FliK family.
messages: Controls the length of the flagellar hook.

1159554:AFK67 RS09740
gene id: 1159554:AFK67_RS09740
uniprot id: A0A0K2P1S7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4-oxalocrotonate tautomerase family. PptA subfamily.
messages: Cytoplasm
messages: Homodimer.

1159554:AFK67 RS09285
gene id: 1159554:AFK67_RS09285
uniprot id: A0A0K2P1P9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.

1159554:AFK67 RS03705
gene id: 1159554:AFK67_RS03705
uniprot id: A0A0K2NYS2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

1159554:AFK67 RS09725
gene id: 1159554:AFK67_RS09725
uniprot id: A0A0K2P1X8
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS13300
gene id: 1159554:AFK67_RS13300
uniprot id: A0A0K2P3S5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1159554:AFK67 RS18130
gene id: 1159554:AFK67_RS18130
uniprot id: A0A0K2P699
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FrdD family.
messages: Cell membrane
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).
messages: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth. Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.

1159554:AFK67 RS01645
gene id: 1159554:AFK67_RS01645
uniprot id: A0A0K2NY65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.
messages: Protein L10 is also a translational repressor protein. It controls the translation of the rplJL-rpoBC operon by binding to its mRNA.

1159554:AFK67 RS12685
gene id: 1159554:AFK67_RS12685
uniprot id: A0A0K2P448
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1159554:AFK67 RS01130
gene id: 1159554:AFK67_RS01130
uniprot id: A0A0K2NXE4
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1159554:AFK67 RS13220
gene id: 1159554:AFK67_RS13220
uniprot id: A0A0K2P3M4
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

1159554:AFK67 RS10505
gene id: 1159554:AFK67_RS10505
uniprot id: A0A0K2P266
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

1159554:AFK67 RS05430
gene id: 1159554:AFK67_RS05430
uniprot id: A0A0K2NZN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1159554:AFK67 RS19305
gene id: 1159554:AFK67_RS19305
uniprot id: A0A0K2P702
names: Similarity
messages: Belongs to the pirin family.

1159554:AFK67 RS03475
gene id: 1159554:AFK67_RS03475
uniprot id: A0A0K2NYM4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

1159554:AFK67 RS04080
gene id: 1159554:AFK67_RS04080
uniprot id: A0A0K2NYU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1159554:AFK67 RS03630
gene id: 1159554:AFK67_RS03630
uniprot id: A0A0K2NYQ5
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1159554:AFK67 RS10620
gene id: 1159554:AFK67_RS10620
uniprot id: A0A0K2P2E1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M14 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in muropeptide degradation. Catalyzes the hydrolysis of the gamma-D-glutamyl-diaminopimelic acid (gamma-D-Glu-Dap) amide bond in the murein tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelic acid, leading to the formation of L-Ala-gamma-D-Glu and Dap.

1159554:AFK67 RS03385
gene id: 1159554:AFK67_RS03385
uniprot id: A0A0K2NYJ7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1159554:AFK67 RS03780
gene id: 1159554:AFK67_RS03780
uniprot id: A0A0K2NYP1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 3 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1159554:AFK67 RS11180
gene id: 1159554:AFK67_RS11180
uniprot id: A0A0K2P399
names: Similarity
messages: Belongs to the CmpA/NrtA family.

1159554:AFK67 RS08770
gene id: 1159554:AFK67_RS08770
uniprot id: A0A0K2P1Z9
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS06470
gene id: 1159554:AFK67_RS06470
uniprot id: A0A0K2P0Q9
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 zinc ion per subunit.

1159554:AFK67 RS00915
gene id: 1159554:AFK67_RS00915
uniprot id: A0A0K2NXA5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Activates expression of the rhaSR operon in response to L-rhamnose.
messages: Binds DNA as a dimer.
messages: Cytoplasm

1159554:AFK67 RS21240
gene id: 1159554:AFK67_RS21240
uniprot id: A0A0K2P8G9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1159554:AFK67 RS13525
gene id: 1159554:AFK67_RS13525
uniprot id: A0A0K2P3T9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS00105
gene id: 1159554:AFK67_RS00105
uniprot id: A0A0K2NWP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions.

1159554:AFK67 RS06595
gene id: 1159554:AFK67_RS06595
uniprot id: A0A0K2P0T7
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

1159554:AFK67 RS02205
gene id: 1159554:AFK67_RS02205
uniprot id: A0A0K2NY03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1159554:AFK67 RS06045
gene id: 1159554:AFK67_RS06045
uniprot id: A0A0K2NZV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS16330
gene id: 1159554:AFK67_RS16330
uniprot id: A0A0K2P586
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1159554:AFK67 RS05995
gene id: 1159554:AFK67_RS05995
uniprot id: A0A0K2NZU3
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1159554:AFK67 RS07845
gene id: 1159554:AFK67_RS07845
uniprot id: A0A0K2P0T9
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

1159554:AFK67 RS14370
gene id: 1159554:AFK67_RS14370
uniprot id: A0A0K2P482
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
messages: Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1159554:AFK67 RS15315
gene id: 1159554:AFK67_RS15315
uniprot id: A0A0K2P4R9
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS11885
gene id: 1159554:AFK67_RS11885
uniprot id: A0A0K2P3M0
names: Similarity
messages: Belongs to the peptidase S24 family.

1159554:AFK67 RS19075
gene id: 1159554:AFK67_RS19075
uniprot id: A0A0K2P6T8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

1159554:AFK67 RS06485
gene id: 1159554:AFK67_RS06485
uniprot id: A0A0K2P033
names: Similarity
messages: Belongs to the ModE family.

1159554:AFK67 RS08445
gene id: 1159554:AFK67_RS08445
uniprot id: A0A0K2P131
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Transforms N(2)-succinylglutamate into succinate and glutamate.

1159554:AFK67 RS07870
gene id: 1159554:AFK67_RS07870
uniprot id: A0A0K2P0U4
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1159554:AFK67 RS16905
gene id: 1159554:AFK67_RS16905
uniprot id: A0A0K2P5K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

1159554:AFK67 RS10365
gene id: 1159554:AFK67_RS10365
uniprot id: A0A0K2P2W8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1159554:AFK67 RS18290
gene id: 1159554:AFK67_RS18290
uniprot id: A0A0K2P714
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell inner membrane
messages: Membrane
messages: Transports acetate.

1159554:AFK67 RS16265
gene id: 1159554:AFK67_RS16265
uniprot id: A0A0K2P576
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm
messages: Homotetramer.

1159554:AFK67 RS08550
gene id: 1159554:AFK67_RS08550
uniprot id: A0A0K2P149
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protease inhibitor I11 (ecotin) family.
messages: General inhibitor of pancreatic serine proteases: inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Periplasm

1159554:AFK67 RS17880
gene id: 1159554:AFK67_RS17880
uniprot id: A0A0K2P638
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1159554:AFK67 RS19050
gene id: 1159554:AFK67_RS19050
uniprot id: A0A0K2P6T4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Monomer.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

1159554:AFK67 RS07330
gene id: 1159554:AFK67_RS07330
uniprot id: A0A0K2P0K0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1159554:AFK67 RS04090
gene id: 1159554:AFK67_RS04090
uniprot id: A0A0K2NZH3
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1159554:AFK67 RS16760
gene id: 1159554:AFK67_RS16760
uniprot id: A0A0K2P657
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1159554:AFK67 RS03265
gene id: 1159554:AFK67_RS03265
uniprot id: A0A0K2NYA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

1159554:AFK67 RS20485
gene id: 1159554:AFK67_RS20485
uniprot id: A0A0K2P7H1
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS15120
gene id: 1159554:AFK67_RS15120
uniprot id: A0A0K2P4Q3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RodZ family.
messages: Cell inner membrane
messages: Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis.
messages: The helix-turn-helix (HTH) motif in the cytoplasmic domain of the N-terminus is involved in the formation of spirals to maintain the rigid rod shape. As this protein is anchored in the cytoplasmic membrane, the HTH motif may contribute to protein-protein interactions to form the RodZ helix, which is localized beneath the cytoplasmic membrane. The C-terminal domain may be critical for determination of the rod shape by probably interacting with enzymes required for synthesis of the peptidoglycan layer, including PBPs in the periplasm.

1159554:AFK67 RS11815
gene id: 1159554:AFK67_RS11815
uniprot id: A0A0K2P300
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.

1159554:AFK67 RS02180
gene id: 1159554:AFK67_RS02180
uniprot id: A0A0K2NXZ8
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

1159554:AFK67 RS21250
gene id: 1159554:AFK67_RS21250
uniprot id: A0A0K2P8E0
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS14415
gene id: 1159554:AFK67_RS14415
uniprot id: A0A0K2P4E1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M74 family.
messages: Binds 2 Zn(2+) ions per subunit. Zn(2+) ion 1 is bound in the active site. Zn(2+) ion 2 is bound at the dimer interface by residues from both subunits.
messages: Dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Murein endopeptidase that cleaves the D-alanyl-meso-2,6-diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus.
messages: Periplasm

1159554:AFK67 RS12285
gene id: 1159554:AFK67_RS12285
uniprot id: A0A0K2P3V4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1159554:AFK67 RS03980
gene id: 1159554:AFK67_RS03980
uniprot id: A0A0K2NZF0
names: Similarity
messages: Belongs to the UPF0325 family.

1159554:AFK67 RS13995
gene id: 1159554:AFK67_RS13995
uniprot id: A0A0K2P409
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1159554:AFK67 RS01240
gene id: 1159554:AFK67_RS01240
uniprot id: A0A0K2NX97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

1159554:AFK67 RS07210
gene id: 1159554:AFK67_RS07210
uniprot id: A0A0K2P187
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

1159554:AFK67 RS13180
gene id: 1159554:AFK67_RS13180
uniprot id: M9NJ39
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1159554:AFK67 RS06360
gene id: 1159554:AFK67_RS06360
uniprot id: A0A0K2P012
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1159554:AFK67 RS09195
gene id: 1159554:AFK67_RS09195
uniprot id: A0A0K2P1N4
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

1159554:AFK67 RS18125
gene id: 1159554:AFK67_RS18125
uniprot id: A0A0K2P686
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FrdC family.
messages: Cell membrane
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).
messages: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth. Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.

1159554:AFK67 RS12710
gene id: 1159554:AFK67_RS12710
uniprot id: A0A0K2P452
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1159554:AFK67 RS14795
gene id: 1159554:AFK67_RS14795
uniprot id: A0A0K2P4F5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

1159554:AFK67 RS15000
gene id: 1159554:AFK67_RS15000
uniprot id: A0A0K2P4J9
names: Subcellular Location Annotation
messages: Cytoplasm

1159554:AFK67 RS01455
gene id: 1159554:AFK67_RS01455
uniprot id: A0A0K2NY31
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

1159554:AFK67 RS04970
gene id: 1159554:AFK67_RS04970
uniprot id: A0A0K2P002
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1159554:AFK67 RS03295
gene id: 1159554:AFK67_RS03295
uniprot id: A0A0K2NYE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1159554:AFK67 RS00360
gene id: 1159554:AFK67_RS00360
uniprot id: A0A0K2NXI8
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS01915
gene id: 1159554:AFK67_RS01915
uniprot id: A0A0K2NYC9
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1159554:AFK67 RS05340
gene id: 1159554:AFK67_RS05340
uniprot id: A0A0K2NZL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1159554:AFK67 RS11520
gene id: 1159554:AFK67_RS11520
uniprot id: A0A0K2P2V9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. Preferentially cleaves at a distance of more than two disaccharide units from the ends of the glycan chain.

1159554:AFK67 RS03665
gene id: 1159554:AFK67_RS03665
uniprot id: A0A0K2NYQ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1159554:AFK67 RS14110
gene id: 1159554:AFK67_RS14110
uniprot id: A0A0K2P484
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MenH family.
messages: Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
messages: Monomer.

1159554:AFK67 RS01825
gene id: 1159554:AFK67_RS01825
uniprot id: A0A0K2NXT8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1159554:AFK67 RS06690
gene id: 1159554:AFK67_RS06690
uniprot id: A0A0K2P0B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

1159554:AFK67 RS11560
gene id: 1159554:AFK67_RS11560
uniprot id: A0A0K2P2Q6
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1159554:AFK67 RS20970
gene id: 1159554:AFK67_RS20970
uniprot id: A0A0K2P8W7
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS13710
gene id: 1159554:AFK67_RS13710
uniprot id: A0A0K2P3W3
names: Similarity
messages: To H.influenzae HI_0842.

1159554:AFK67 RS03120
gene id: 1159554:AFK67_RS03120
uniprot id: A0A0K2NYY0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

1159554:AFK67 RS05415
gene id: 1159554:AFK67_RS05415
uniprot id: A0A0K2NZM5
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1159554:AFK67 RS06280
gene id: 1159554:AFK67_RS06280
uniprot id: A0A0K2NZX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

1159554:AFK67 RS02595
gene id: 1159554:AFK67_RS02595
uniprot id: A0A0K2NY18
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1159554:AFK67 RS01180
gene id: 1159554:AFK67_RS01180
uniprot id: A0A0K2NXX1
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1159554:AFK67 RS13470
gene id: 1159554:AFK67_RS13470
uniprot id: A0A0K2P3S9
names: Similarity
messages: Belongs to the peptidase S11 family.

1159554:AFK67 RS04930
gene id: 1159554:AFK67_RS04930
uniprot id: A0A0K2NZ73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

1159554:AFK67 RS01470
gene id: 1159554:AFK67_RS01470
uniprot id: A0A0K2NXH8
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1159554:AFK67 RS21230
gene id: 1159554:AFK67_RS21230
uniprot id: A0A0K2P8H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Metabolite:H+ Symporter (MHS) family (TC 2.A.1.6) family.
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS17235
gene id: 1159554:AFK67_RS17235
uniprot id: A0A0K2P5V9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1159554:AFK67 RS11105
gene id: 1159554:AFK67_RS11105
uniprot id: A0A0K2P2I5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1159554:AFK67 RS18005
gene id: 1159554:AFK67_RS18005
uniprot id: A0A0K2P673
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm
messages: Monomer.

1159554:AFK67 RS08210
gene id: 1159554:AFK67_RS08210
uniprot id: A0A0K2P1R0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1159554:AFK67 RS00120
gene id: 1159554:AFK67_RS00120
uniprot id: A0A0K2NWZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS09205
gene id: 1159554:AFK67_RS09205
uniprot id: A0A0K2P1M3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

1159554:AFK67 RS08325
gene id: 1159554:AFK67_RS08325
uniprot id: A0A0K2P7Q2
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS16885
gene id: 1159554:AFK67_RS16885
uniprot id: A0A0K2P5P1
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

1159554:AFK67 RS11065
gene id: 1159554:AFK67_RS11065
uniprot id: A0A0K2P2L9
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1159554:AFK67 RS10990
gene id: 1159554:AFK67_RS10990
uniprot id: A0A0K2P2G5
names: Similarity
messages: Belongs to the YciI family.

1159554:AFK67 RS07040
gene id: 1159554:AFK67_RS07040
uniprot id: A0A0K2P0H4
names: Similarity
messages: Belongs to the UPF0145 family.

1159554:AFK67 RS00050
gene id: 1159554:AFK67_RS00050
uniprot id: A0A0K2NWV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1159554:AFK67 RS17065
gene id: 1159554:AFK67_RS17065
uniprot id: A0A0K2P6A7
names: Similarity
messages: Belongs to the EndA/NucM nuclease family.

1159554:AFK67 RS15620
gene id: 1159554:AFK67_RS15620
uniprot id: A0A0K2P523
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1159554:AFK67 RS13495
gene id: 1159554:AFK67_RS13495
uniprot id: A0A0K2P7Z6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1159554:AFK67 RS17920
gene id: 1159554:AFK67_RS17920
uniprot id: A0A0K2P6V5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RIC family. YtfE subfamily.
messages: Cytoplasm
messages: Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions.
messages: Homodimer.

1159554:AFK67 RS03540
gene id: 1159554:AFK67_RS03540
uniprot id: A0A0K2NYM8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: The complex is composed of two ATP-binding proteins (ThiQ), two transmembrane proteins (ThiP) and a solute-binding protein (ThiB).

1159554:AFK67 RS14715
gene id: 1159554:AFK67_RS14715
uniprot id: A0A0K2P4I0
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1159554:AFK67 RS14335
gene id: 1159554:AFK67_RS14335
uniprot id: A0A0K2P477
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS15540
gene id: 1159554:AFK67_RS15540
uniprot id: A0A0K2P4U9
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1159554:AFK67 RS03610
gene id: 1159554:AFK67_RS03610
uniprot id: A0A0K2NZ64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster. Acts by binding directly to DNA. May also regulate the expression of genes outside the dcw cluster.
messages: nucleoid

1159554:AFK67 RS11050
gene id: 1159554:AFK67_RS11050
uniprot id: A0A0K2P2I7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

1159554:AFK67 RS19950
gene id: 1159554:AFK67_RS19950
uniprot id: A0A0K2P780
names: Cofactor
messages: Binds 1 Ca(2+) ion per subunit.

1159554:AFK67 RS09355
gene id: 1159554:AFK67_RS09355
uniprot id: A0A0K2P1M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

1159554:AFK67 RS04165
gene id: 1159554:AFK67_RS04165
uniprot id: A0A0K2NZJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

1159554:AFK67 RS19420
gene id: 1159554:AFK67_RS19420
uniprot id: A0A0K2P849
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

1159554:AFK67 RS09550
gene id: 1159554:AFK67_RS09550
uniprot id: A0A0K2P1T8
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

1159554:AFK67 RS19600
gene id: 1159554:AFK67_RS19600
uniprot id: A0A0K2P737
names: Similarity
messages: Belongs to the glutamine synthetase family.

1159554:AFK67 RS04440
gene id: 1159554:AFK67_RS04440
uniprot id: A0A0K2NZ20
names: Function
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.

1159554:AFK67 RS11625
gene id: 1159554:AFK67_RS11625
uniprot id: A0A0K2P7U1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

1159554:AFK67 RS12520
gene id: 1159554:AFK67_RS12520
uniprot id: A0A0K2P3E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm

1159554:AFK67 RS08025
gene id: 1159554:AFK67_RS08025
uniprot id: A0A0K2P123
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LpoB family.
messages: Interacts with PBP1b.
messages: Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b).

1159554:AFK67 RS19070
gene id: 1159554:AFK67_RS19070
uniprot id: A0A0K2P7E7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

1159554:AFK67 RS18900
gene id: 1159554:AFK67_RS18900
uniprot id: A0A0K2P6Q5
names: Similarity
messages: Belongs to the SlyX family.

1159554:AFK67 RS00775
gene id: 1159554:AFK67_RS00775
uniprot id: A0A0K2NX10
names: Similarity
messages: Belongs to the mannitol dehydrogenase family.

1159554:AFK67 RS00070
gene id: 1159554:AFK67_RS00070
uniprot id: A0A0K2NXE2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1159554:AFK67 RS14920
gene id: 1159554:AFK67_RS14920
uniprot id: A0A0K2P4L8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1159554:AFK67 RS02715
gene id: 1159554:AFK67_RS02715
uniprot id: A0A0K2NY10
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

1159554:AFK67 RS01490
gene id: 1159554:AFK67_RS01490
uniprot id: A0A0K2NXE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1159554:AFK67 RS04295
gene id: 1159554:AFK67_RS04295
uniprot id: A0A0K2P8C2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Gram-negative porin family.
messages: Cell outer membrane
messages: Homotrimer.
messages: Membrane

1159554:AFK67 RS01830
gene id: 1159554:AFK67_RS01830
uniprot id: A0A0K2NYB5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1159554:AFK67 RS01985
gene id: 1159554:AFK67_RS01985
uniprot id: A0A0K2NXW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1159554:AFK67 RS16765
gene id: 1159554:AFK67_RS16765
uniprot id: A0A0K2P5K3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1159554:AFK67 RS12825
gene id: 1159554:AFK67_RS12825
uniprot id: A0A0K2P3F4
names: Function
names: Similarity
messages: Belongs to the RcsA family.
messages: Component of the Rcs signaling system, which controls transcription of numerous genes. Binds to DNA to regulate expression of genes.

1159554:AFK67 RS17305
gene id: 1159554:AFK67_RS17305
uniprot id: A0A0K2P5T2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1159554:AFK67 RS10095
gene id: 1159554:AFK67_RS10095
uniprot id: A0A0K2P212
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS03680
gene id: 1159554:AFK67_RS03680
uniprot id: A0A0K2NYR7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1159554:AFK67 RS20520
gene id: 1159554:AFK67_RS20520
uniprot id: A0A0K2P7M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Responsible for the low-affinity transport of potassium into the cell, with the probable concomitant uptake of protons (symport system).

1159554:AFK67 RS18245
gene id: 1159554:AFK67_RS18245
uniprot id: A0A0K2P6C0
names: Similarity
messages: Belongs to the YjdM family.

1159554:AFK67 RS03740
gene id: 1159554:AFK67_RS03740
uniprot id: A0A0K2NYR8
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1159554:AFK67 RS00925
gene id: 1159554:AFK67_RS00925
uniprot id: A0A0K2P7K9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Homodimer.

1159554:AFK67 RS12805
gene id: 1159554:AFK67_RS12805
uniprot id: A0A0K2P3G2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

1159554:AFK67 RS19365
gene id: 1159554:AFK67_RS19365
uniprot id: A0A0K2P6Z0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1159554:AFK67 RS14480
gene id: 1159554:AFK67_RS14480
uniprot id: A0A0K2P4Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS03655
gene id: 1159554:AFK67_RS03655
uniprot id: A0A0K2NYR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

1159554:AFK67 RS07765
gene id: 1159554:AFK67_RS07765
uniprot id: A0A0K2P0Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family.
messages: Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).
messages: Cell inner membrane

1159554:AFK67 RS18300
gene id: 1159554:AFK67_RS18300
uniprot id: A0A0K2P6B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

1159554:AFK67 RS16875
gene id: 1159554:AFK67_RS16875
uniprot id: A0A0K2P5I8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

1159554:AFK67 RS09250
gene id: 1159554:AFK67_RS09250
uniprot id: A0A0K2P1K1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1159554:AFK67 RS12895
gene id: 1159554:AFK67_RS12895
uniprot id: A0A0K2P3M8
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1159554:AFK67 RS17135
gene id: 1159554:AFK67_RS17135
uniprot id: A0A0K2P5U0
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

1159554:AFK67 RS03365
gene id: 1159554:AFK67_RS03365
uniprot id: A0A0K2NYC4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1159554:AFK67 RS02670
gene id: 1159554:AFK67_RS02670
uniprot id: A0A0K2NY33
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1159554:AFK67 RS11045
gene id: 1159554:AFK67_RS11045
uniprot id: A0A0K2P2H5
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

1159554:AFK67 RS09220
gene id: 1159554:AFK67_RS09220
uniprot id: A0A0K2P7W3
names: Similarity
messages: Belongs to the GST superfamily.

1159554:AFK67 RS00790
gene id: 1159554:AFK67_RS00790
uniprot id: A0A0K2NXP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers. Binds only one seryl-tRNA(Sec) per dimer.

1159554:AFK67 RS04245
gene id: 1159554:AFK67_RS04245
uniprot id: A0A0K2NZK3
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1159554:AFK67 RS02195
gene id: 1159554:AFK67_RS02195
uniprot id: A0A0K2NXR5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1159554:AFK67 RS01515
gene id: 1159554:AFK67_RS01515
uniprot id: A0A0K2NXF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RfaH family.
messages: Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. RfaH is recruited into a multi-component RNA polymerase complex by the ops element, which is a short conserved DNA sequence located downstream of the main promoter of these operons. Once bound, RfaH suppresses pausing and inhibits Rho-dependent and intrinsic termination at a subset of sites. Termination signals are bypassed, which allows complete synthesis of long RNA chains.
messages: Interacts with both the nontemplate DNA and the RNA polymerase (RNAP).

1159554:AFK67 RS08515
gene id: 1159554:AFK67_RS08515
uniprot id: A0A0K2P195
names: Similarity
messages: Belongs to the fructosamine kinase family.

1159554:AFK67 RS06230
gene id: 1159554:AFK67_RS06230
uniprot id: A0A0K2NZW1
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS16630
gene id: 1159554:AFK67_RS16630
uniprot id: A0A0K2P5J2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: Homohexamer.

1159554:AFK67 RS11195
gene id: 1159554:AFK67_RS11195
uniprot id: A0A0K2P2K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1159554:AFK67 RS03515
gene id: 1159554:AFK67_RS03515
uniprot id: A0A0K2NYM3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.
messages: Homohexamer.

1159554:AFK67 RS09270
gene id: 1159554:AFK67_RS09270
uniprot id: A0A0K2P7V7
names: Similarity
messages: Belongs to the Hha/YmoA/Cnu family.

1159554:AFK67 RS18575
gene id: 1159554:AFK67_RS18575
uniprot id: A0A0K2P6L8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS13095
gene id: 1159554:AFK67_RS13095
uniprot id: A0A0K2P3J7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1159554:AFK67 RS03065
gene id: 1159554:AFK67_RS03065
uniprot id: A0A0K2NYE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. RsmC family.
messages: Cytoplasm
messages: Monomer.
messages: Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.

1159554:AFK67 RS01960
gene id: 1159554:AFK67_RS01960
uniprot id: A0A0K2NXW1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family.
messages: Cell membrane
messages: Forms an efflux pump with AaeA. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1159554:AFK67 RS02015
gene id: 1159554:AFK67_RS02015
uniprot id: A0A0K2NXW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1159554:AFK67 RS01920
gene id: 1159554:AFK67_RS01920
uniprot id: A0A0K2NXT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

1159554:AFK67 RS05350
gene id: 1159554:AFK67_RS05350
uniprot id: A0A0K2NZI0
names: Subcellular Location Annotation
messages: Cell inner membrane

1159554:AFK67 RS12700
gene id: 1159554:AFK67_RS12700
uniprot id: A0A0K2P3E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1159554:AFK67 RS15570
gene id: 1159554:AFK67_RS15570
uniprot id: A0A0K2P510
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1159554:AFK67 RS07675
gene id: 1159554:AFK67_RS07675
uniprot id: A0A0K2P0V5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the PHP family.
messages: Binds 3 Zn(2+) ions per subunit.
messages: Homotrimer.

1159554:AFK67 RS03510
gene id: 1159554:AFK67_RS03510
uniprot id: A0A0K2NZ45
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldolase class II family. AraD/FucA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Homotetramer.
messages: Involved in the degradation of L-arabinose. Catalyzes the interconversion of L-ribulose 5-phosphate (LRu5P) and D-xylulose 5-phosphate (D-Xu5P) via a retroaldol/aldol mechanism (carbon-carbon bond cleavage analogous to a class II aldolase reaction).

1159554:AFK67 RS00795
gene id: 1159554:AFK67_RS00795
uniprot id: A0A0K2NX85
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

1159554:AFK67 RS04920
gene id: 1159554:AFK67_RS04920
uniprot id: A0A0K2NZD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1159554:AFK67 RS13455
gene id: 1159554:AFK67_RS13455
uniprot id: A0A0K2P4H5
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

1159554:AFK67 RS10035
gene id: 1159554:AFK67_RS10035
uniprot id: A0A0K2P201
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1159554:AFK67 RS07775
gene id: 1159554:AFK67_RS07775
uniprot id: A0A0K2P0X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0312 family. Type 1 subfamily.
messages: Periplasm

1159554:AFK67 RS16650
gene id: 1159554:AFK67_RS16650
uniprot id: A0A0K2P5E9
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

1159554:AFK67 RS09335
gene id: 1159554:AFK67_RS09335
uniprot id: A0A0K2P1Q9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1159554:AFK67 RS01220
gene id: 1159554:AFK67_RS01220
uniprot id: A0A0K2NXD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

1159554:AFK67 RS17630
gene id: 1159554:AFK67_RS17630
uniprot id: A0A0K2P605
names: Subunit
messages: Monomer.

1159554:AFK67 RS04855
gene id: 1159554:AFK67_RS04855
uniprot id: A0A0K2NZD6
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

1159554:AFK67 RS09310
gene id: 1159554:AFK67_RS09310
uniprot id: A0A0K2P1Q4
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

1159554:AFK67 RS17840
gene id: 1159554:AFK67_RS17840
uniprot id: A0A0K2P667
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS01855
gene id: 1159554:AFK67_RS01855
uniprot id: A0A0K2P7L5
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1159554:AFK67 RS00310
gene id: 1159554:AFK67_RS00310
uniprot id: A0A0K2NXI1
names: Similarity
names: Subunit
messages: Belongs to the KHG/KDPG aldolase family.
messages: Homotrimer.

1159554:AFK67 RS13665
gene id: 1159554:AFK67_RS13665
uniprot id: A0A0K2P407
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS05455
gene id: 1159554:AFK67_RS05455
uniprot id: A0A0K2NZP1
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS10380
gene id: 1159554:AFK67_RS10380
uniprot id: A0A0K2P264
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS08115
gene id: 1159554:AFK67_RS08115
uniprot id: A0A0K2P0X2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

1159554:AFK67 RS20290
gene id: 1159554:AFK67_RS20290
uniprot id: A0A0K2P7E5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1159554:AFK67 RS02965
gene id: 1159554:AFK67_RS02965
uniprot id: A0A0K2NY83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

1159554:AFK67 RS02405
gene id: 1159554:AFK67_RS02405
uniprot id: A0A0K2NXY5
names: Similarity
messages: Belongs to the pirin family.

1159554:AFK67 RS00160
gene id: 1159554:AFK67_RS00160
uniprot id: A0A0K2NXF7
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1159554:AFK67 RS12800
gene id: 1159554:AFK67_RS12800
uniprot id: A0A0K2P3F0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1159554:AFK67 RS18440
gene id: 1159554:AFK67_RS18440
uniprot id: A0A0K2P6J3
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1159554:AFK67 RS05485
gene id: 1159554:AFK67_RS05485
uniprot id: A0A0K2P089
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS18875
gene id: 1159554:AFK67_RS18875
uniprot id: A0A0K2P6Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DsrH/TusB family.
messages: Cytoplasm
messages: Heterohexamer, formed by a dimer of trimers. The hexameric TusBCD complex contains 2 copies each of TusB, TusC and TusD. The TusBCD complex interacts with TusE.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.

1159554:AFK67 RS15110
gene id: 1159554:AFK67_RS15110
uniprot id: A0A0K2P4R1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1159554:AFK67 RS09230
gene id: 1159554:AFK67_RS09230
uniprot id: A0A0K2P1N9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1159554:AFK67 RS16900
gene id: 1159554:AFK67_RS16900
uniprot id: A0A0K2P5J3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA-modifying YgfZ family.
messages: Cytoplasm
messages: Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication.

1159554:AFK67 RS06065
gene id: 1159554:AFK67_RS06065
uniprot id: A0A0K2NZT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS17360
gene id: 1159554:AFK67_RS17360
uniprot id: A0A0K2P5V0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1159554:AFK67 RS17140
gene id: 1159554:AFK67_RS17140
uniprot id: A0A0K2P6C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1159554:AFK67 RS09330
gene id: 1159554:AFK67_RS09330
uniprot id: A0A0K2P1L6
names: Subcellular Location Annotation
messages: Cell inner membrane

1159554:AFK67 RS04655
gene id: 1159554:AFK67_RS04655
uniprot id: A0A0K2NZU5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

1159554:AFK67 RS20255
gene id: 1159554:AFK67_RS20255
uniprot id: A0A0K2P7G7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoid occlusion factor SlmA family.
messages: Homodimer. Interacts with FtsZ.
messages: Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
messages: nucleoid

1159554:AFK67 RS02990
gene id: 1159554:AFK67_RS02990
uniprot id: A0A0K2NY87
names: Function
names: Similarity
messages: Belongs to the DnaT family.
messages: This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with DnaB protein and other prepriming proteins DnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'.

1159554:AFK67 RS09560
gene id: 1159554:AFK67_RS09560
uniprot id: A0A0K2P1P1
names: Function
messages: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds.

1159554:AFK67 RS08815
gene id: 1159554:AFK67_RS08815
uniprot id: A0A0K2P1H0
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS10530
gene id: 1159554:AFK67_RS10530
uniprot id: A0A0K2P2C4
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1159554:AFK67 RS19905
gene id: 1159554:AFK67_RS19905
uniprot id: A0A0K2P7C0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1159554:AFK67 RS16870
gene id: 1159554:AFK67_RS16870
uniprot id: A0A0K2P5M4
names: Similarity
messages: Belongs to the RecJ family.

1159554:AFK67 RS13350
gene id: 1159554:AFK67_RS13350
uniprot id: A0A0K2P4F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS03140
gene id: 1159554:AFK67_RS03140
uniprot id: A0A0K2NYG0
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1159554:AFK67 RS04525
gene id: 1159554:AFK67_RS04525
uniprot id: A0A0K2NZS1
names: Similarity
messages: Belongs to the TPP enzyme family.

1159554:AFK67 RS15565
gene id: 1159554:AFK67_RS15565
uniprot id: A0A0K2P4V2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1159554:AFK67 RS20615
gene id: 1159554:AFK67_RS20615
uniprot id: A0A0K2P8K0
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS01225
gene id: 1159554:AFK67_RS01225
uniprot id: A0A0K2NXH6
names: Function
names: Similarity
messages: Belongs to the GppA/Ppx family. GppA subfamily.
messages: Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.

1159554:AFK67 RS02325
gene id: 1159554:AFK67_RS02325
uniprot id: A0A0K2NY22
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1159554:AFK67 RS14975
gene id: 1159554:AFK67_RS14975
uniprot id: A0A0K2P4J4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcA family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: nucleolus

1159554:AFK67 RS08610
gene id: 1159554:AFK67_RS08610
uniprot id: A0A0K2P1C9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF).

1159554:AFK67 RS07355
gene id: 1159554:AFK67_RS07355
uniprot id: A0A0K2P0K3
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the SsuD family.
messages: Catalyzes the desulfonation of aliphatic sulfonates.
messages: FMNH(2) which is absolutely required for this enzymatic reaction, is provided by SsuE.
messages: Homotetramer.

1159554:AFK67 RS12360
gene id: 1159554:AFK67_RS12360
uniprot id: A0A0K2P3X0
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

1159554:AFK67 RS10970
gene id: 1159554:AFK67_RS10970
uniprot id: A0A0K2P2H2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

1159554:AFK67 RS03955
gene id: 1159554:AFK67_RS03955
uniprot id: A0A0K2NZE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1159554:AFK67 RS00885
gene id: 1159554:AFK67_RS00885
uniprot id: A0A0K2P899
names: Subcellular Location Annotation
messages: Cell inner membrane

1159554:AFK67 RS11130
gene id: 1159554:AFK67_RS11130
uniprot id: A0A0K2P2J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS02780
gene id: 1159554:AFK67_RS02780
uniprot id: A0A0K2NY97
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1159554:AFK67 RS04490
gene id: 1159554:AFK67_RS04490
uniprot id: A0A0K2NZ29
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.
messages: Homotetramer.

1159554:AFK67 RS20085
gene id: 1159554:AFK67_RS20085
uniprot id: A0A0K2P7A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

1159554:AFK67 RS16585
gene id: 1159554:AFK67_RS16585
uniprot id: A0A0K2P5D7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1159554:AFK67 RS08650
gene id: 1159554:AFK67_RS08650
uniprot id: A0A0K2P168
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1159554:AFK67 RS03735
gene id: 1159554:AFK67_RS03735
uniprot id: A0A0K2NZ96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the N-Me-Phe pilin family.
messages: Membrane

1159554:AFK67 RS03675
gene id: 1159554:AFK67_RS03675
uniprot id: A0A0K2NYM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1159554:AFK67 RS12325
gene id: 1159554:AFK67_RS12325
uniprot id: A0A0K2P368
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
messages: Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
messages: Homotetramer.

1159554:AFK67 RS02495
gene id: 1159554:AFK67_RS02495
uniprot id: A0A0K2NY50
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

1159554:AFK67 RS04270
gene id: 1159554:AFK67_RS04270
uniprot id: A0A0K2NZK9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1159554:AFK67 RS07190
gene id: 1159554:AFK67_RS07190
uniprot id: A0A0K2P0L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

1159554:AFK67 RS15355
gene id: 1159554:AFK67_RS15355
uniprot id: A0A0K2P4W0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1159554:AFK67 RS12270
gene id: 1159554:AFK67_RS12270
uniprot id: A0A0K2P346
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS15350
gene id: 1159554:AFK67_RS15350
uniprot id: A0A0K2P5I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1159554:AFK67 RS18690
gene id: 1159554:AFK67_RS18690
uniprot id: A0A0K2P778
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

1159554:AFK67 RS17180
gene id: 1159554:AFK67_RS17180
uniprot id: A0A0K2P5Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS06050
gene id: 1159554:AFK67_RS06050
uniprot id: A0A0K2NZZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS04200
gene id: 1159554:AFK67_RS04200
uniprot id: A0A0K2NYU3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1159554:AFK67 RS15635
gene id: 1159554:AFK67_RS15635
uniprot id: A0A0K2P4W7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1159554:AFK67 RS19295
gene id: 1159554:AFK67_RS19295
uniprot id: A0A0K2P6U2
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

1159554:AFK67 RS09730
gene id: 1159554:AFK67_RS09730
uniprot id: A0A0K2P2I9
names: Function
names: Similarity
messages: Belongs to the class-C beta-lactamase family.
messages: This protein is a serine beta-lactamase with a substrate specificity for cephalosporins.

1159554:AFK67 RS08350
gene id: 1159554:AFK67_RS08350
uniprot id: A0A0K2P1T2
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

1159554:AFK67 RS11040
gene id: 1159554:AFK67_RS11040
uniprot id: A0A0K2P2L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS20585
gene id: 1159554:AFK67_RS20585
uniprot id: A0A0K2P861
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1159554:AFK67 RS19525
gene id: 1159554:AFK67_RS19525
uniprot id: A0A0K2P722
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1159554:AFK67 RS15575
gene id: 1159554:AFK67_RS15575
uniprot id: A0A0K2P5L8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1159554:AFK67 RS06310
gene id: 1159554:AFK67_RS06310
uniprot id: A0A0K2P000
names: Similarity
messages: Belongs to the citrate synthase family.

1159554:AFK67 RS10730
gene id: 1159554:AFK67_RS10730
uniprot id: A0A0K2P2A6
names: Similarity
messages: Belongs to the YkuD family.

1159554:AFK67 RS06780
gene id: 1159554:AFK67_RS06780
uniprot id: A0A0K2P067
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1159554:AFK67 RS01120
gene id: 1159554:AFK67_RS01120
uniprot id: A0A0K2NXW4
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
messages: Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).

1159554:AFK67 RS14145
gene id: 1159554:AFK67_RS14145
uniprot id: A0A0K2P483
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4 family.
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: Membrane

1159554:AFK67 RS10945
gene id: 1159554:AFK67_RS10945
uniprot id: A0A0K2P2G7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1159554:AFK67 RS08850
gene id: 1159554:AFK67_RS08850
uniprot id: A0A0K2P1G4
names: Function
names: Similarity
messages: Belongs to the GlgS family.
messages: Major determinant of cell surface composition. Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides.

1159554:AFK67 RS14325
gene id: 1159554:AFK67_RS14325
uniprot id: A0A0K2P4W4
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1159554:AFK67 RS20695
gene id: 1159554:AFK67_RS20695
uniprot id: A0A0K2P8R5
names: Similarity
messages: Belongs to the VgrG protein family.

1159554:AFK67 RS16560
gene id: 1159554:AFK67_RS16560
uniprot id: A0A0K2P5D1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS15595
gene id: 1159554:AFK67_RS15595
uniprot id: A0A0K2P517
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1159554:AFK67 RS01690
gene id: 1159554:AFK67_RS01690
uniprot id: A0A0K2NXR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1159554:AFK67 RS01350
gene id: 1159554:AFK67_RS01350
uniprot id: A0A0K2NY06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-1 family.
messages: Cytoplasm

1159554:AFK67 RS00350
gene id: 1159554:AFK67_RS00350
uniprot id: A0A0K2NWY6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1159554:AFK67 RS07225
gene id: 1159554:AFK67_RS07225
uniprot id: A0A0K2P0J1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1159554:AFK67 RS15045
gene id: 1159554:AFK67_RS15045
uniprot id: A0A0K2P4P4
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1159554:AFK67 RS06265
gene id: 1159554:AFK67_RS06265
uniprot id: A0A0K2P031
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
messages: Provides significant protection from radiation damage and may be involved in the degradation of radiation-damaged nucleotides.
messages: Toroid-shaped homohexamer. In the hexamer, 3 dimers assemble to form a ring-like structure surrounding a central hole.

1159554:AFK67 RS18545
gene id: 1159554:AFK67_RS18545
uniprot id: A0A0K2P6H1
names: Similarity
messages: Belongs to the aspartokinase family.

1159554:AFK67 RS14450
gene id: 1159554:AFK67_RS14450
uniprot id: A0A0K2P4Y8
names: Similarity
messages: Belongs to the UPF0381 family.

1159554:AFK67 RS03800
gene id: 1159554:AFK67_RS03800
uniprot id: A0A0K2NZA7
names: Similarity
messages: Belongs to the UPF0231 family.

1159554:AFK67 RS09465
gene id: 1159554:AFK67_RS09465
uniprot id: A0A0K2P2D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS05500
gene id: 1159554:AFK67_RS05500
uniprot id: A0A0K2NZL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1159554:AFK67 RS02350
gene id: 1159554:AFK67_RS02350
uniprot id: A0A0K2NY27
names: Similarity
messages: Belongs to the UPF0213 family.

1159554:AFK67 RS17025
gene id: 1159554:AFK67_RS17025
uniprot id: A0A0K2P5L6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1159554:AFK67 RS02540
gene id: 1159554:AFK67_RS02540
uniprot id: A0A0K2NY09
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1159554:AFK67 RS14140
gene id: 1159554:AFK67_RS14140
uniprot id: A0A0K2P4T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1159554:AFK67 RS11765
gene id: 1159554:AFK67_RS11765
uniprot id: A0A0K2P2Y9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS19105
gene id: 1159554:AFK67_RS19105
uniprot id: A0A0K2P6U3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

1159554:AFK67 RS14135
gene id: 1159554:AFK67_RS14135
uniprot id: A0A0K2P490
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family. RNase BN subfamily.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which has both exoribonuclease and endoribonuclease activities.

1159554:AFK67 RS17945
gene id: 1159554:AFK67_RS17945
uniprot id: A0A0K2P6V9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1159554:AFK67 RS00280
gene id: 1159554:AFK67_RS00280
uniprot id: A0A0K2NX19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1159554:AFK67 RS08395
gene id: 1159554:AFK67_RS08395
uniprot id: A0A0K2P143
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Binds two Mg(2+) per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1159554:AFK67 RS04685
gene id: 1159554:AFK67_RS04685
uniprot id: A0A0K2NZ92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS01550
gene id: 1159554:AFK67_RS01550
uniprot id: A0A0K2NXN0
names: Similarity
messages: Belongs to the IMPACT family.

1159554:AFK67 RS05400
gene id: 1159554:AFK67_RS05400
uniprot id: A0A0K2NZI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1159554:AFK67 RS08615
gene id: 1159554:AFK67_RS08615
uniprot id: A0A0K2P1X3
names: Function
names: Similarity
messages: Belongs to the glutathione peroxidase family. BtuE subfamily.
messages: Non-specific peroxidase that can use thioredoxin or glutathione as a reducing agent.

1159554:AFK67 RS03990
gene id: 1159554:AFK67_RS03990
uniprot id: A0A0K2P7N1
names: Activity Regulation
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

1159554:AFK67 RS07115
gene id: 1159554:AFK67_RS07115
uniprot id: A0A0K2P0K1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1159554:AFK67 RS17005
gene id: 1159554:AFK67_RS17005
uniprot id: A0A0K2P5M2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1159554:AFK67 RS05955
gene id: 1159554:AFK67_RS05955
uniprot id: A0A0K2P0G1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1159554:AFK67 RS13650
gene id: 1159554:AFK67_RS13650
uniprot id: A0A0K2P3Z2
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS06210
gene id: 1159554:AFK67_RS06210
uniprot id: A0A0K2NZX8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1159554:AFK67 RS15335
gene id: 1159554:AFK67_RS15335
uniprot id: A0A0K2P4S4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1159554:AFK67 RS18885
gene id: 1159554:AFK67_RS18885
uniprot id: A0A0K2P6M9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm
messages: Heterohexamer, formed by a dimer of trimers. The hexameric TusBCD complex contains 2 copies each of TusB, TusC and TusD. The TusBCD complex interacts with TusE.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE.

1159554:AFK67 RS16200
gene id: 1159554:AFK67_RS16200
uniprot id: A0A0K2P5C2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1159554:AFK67 RS10290
gene id: 1159554:AFK67_RS10290
uniprot id: A0A0K2P2V1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell inner membrane
messages: Cell membrane
messages: Forms a complex with MdtJ.
messages: Membrane

1159554:AFK67 RS01090
gene id: 1159554:AFK67_RS01090
uniprot id: A0A0K2NXF6
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1159554:AFK67 RS17200
gene id: 1159554:AFK67_RS17200
uniprot id: A0A0K2P5Q5
names: Function
names: Similarity
messages: Belongs to the CitG/MdcB family.
messages: Involved in the formation of 2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase.

1159554:AFK67 RS15345
gene id: 1159554:AFK67_RS15345
uniprot id: A0A0K2P4X5
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1159554:AFK67 RS12845
gene id: 1159554:AFK67_RS12845
uniprot id: A0A0K2P475
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.

1159554:AFK67 RS01060
gene id: 1159554:AFK67_RS01060
uniprot id: A0A0K2NXA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

1159554:AFK67 RS05470
gene id: 1159554:AFK67_RS05470
uniprot id: A0A0K2NZH6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1159554:AFK67 RS12995
gene id: 1159554:AFK67_RS12995
uniprot id: A0A0K2P497
names: Similarity
messages: Belongs to the VgrG protein family.

1159554:AFK67 RS03920
gene id: 1159554:AFK67_RS03920
uniprot id: A0A0K2NYR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1159554:AFK67 RS02900
gene id: 1159554:AFK67_RS02900
uniprot id: A0A0K2NYU5
names: Caution
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the porin LamB (TC 1.B.3) family.
messages: By maltose.
messages: Cell outer membrane
messages: Homotrimer formed of three 18-stranded antiparallel beta-barrels, containing three independent channels.
messages: Involved in the transport of maltose and maltodextrins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1159554:AFK67 RS02210
gene id: 1159554:AFK67_RS02210
uniprot id: A0A0K2NYI1
names: Subcellular Location Annotation
messages: Cell inner membrane

1159554:AFK67 RS17670
gene id: 1159554:AFK67_RS17670
uniprot id: A0A0K2P628
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1159554:AFK67 RS06395
gene id: 1159554:AFK67_RS06395
uniprot id: A0A0K2P0P7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1159554:AFK67 RS09370
gene id: 1159554:AFK67_RS09370
uniprot id: A0A0K2P1Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1159554:AFK67 RS07610
gene id: 1159554:AFK67_RS07610
uniprot id: A0A0K2P1F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1159554:AFK67 RS17560
gene id: 1159554:AFK67_RS17560
uniprot id: A0A0K2P6L4
names: Similarity
messages: Belongs to the porin LamB (TC 1.B.3) family.

1159554:AFK67 RS01750
gene id: 1159554:AFK67_RS01750
uniprot id: A0A0K2NYA6
names: Similarity
messages: Belongs to the GARS family.

1159554:AFK67 RS18400
gene id: 1159554:AFK67_RS18400
uniprot id: A0A0K2P6G9
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1159554:AFK67 RS16910
gene id: 1159554:AFK67_RS16910
uniprot id: A0A0K2P5P6
names: Function
names: Similarity
messages: Belongs to the N(4)-acetylcytidine amidohydrolase family.
messages: Catalyzes the hydrolysis of N(4)-acetylcytidine (ac4C).

1159554:AFK67 RS11705
gene id: 1159554:AFK67_RS11705
uniprot id: A0A0K2P2Z7
names: Function
names: Similarity
messages: Belongs to the Nudix hydrolase family. PCD1 subfamily.
messages: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.

1159554:AFK67 RS04195
gene id: 1159554:AFK67_RS04195
uniprot id: A0A0K2NYZ5
names: Subunit
messages: Monomer.

1159554:AFK67 RS09100
gene id: 1159554:AFK67_RS09100
uniprot id: A0A0K2P1K3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1159554:AFK67 RS08155
gene id: 1159554:AFK67_RS08155
uniprot id: A0A0K2P1Q1
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS10025
gene id: 1159554:AFK67_RS10025
uniprot id: A0A0K2P239
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1159554:AFK67 RS02940
gene id: 1159554:AFK67_RS02940
uniprot id: A0A0K2NY80
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1159554:AFK67 RS11715
gene id: 1159554:AFK67_RS11715
uniprot id: A0A0K2P2Y0
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS06460
gene id: 1159554:AFK67_RS06460
uniprot id: A0A0K2P027
names: Similarity
messages: Belongs to the aldose epimerase family.

1159554:AFK67 RS06055
gene id: 1159554:AFK67_RS06055
uniprot id: A0A0K2P0H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS06775
gene id: 1159554:AFK67_RS06775
uniprot id: A0A0K2P0C7
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS11920
gene id: 1159554:AFK67_RS11920
uniprot id: A0A0K2P338
names: Similarity
messages: Belongs to the peptidase C40 family.

1159554:AFK67 RS06010
gene id: 1159554:AFK67_RS06010
uniprot id: A0A0K2NZY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1159554:AFK67 RS13105
gene id: 1159554:AFK67_RS13105
uniprot id: A0A0K2P3R1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1159554:AFK67 RS06545
gene id: 1159554:AFK67_RS06545
uniprot id: A0A0K2P0S7
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

1159554:AFK67 RS16495
gene id: 1159554:AFK67_RS16495
uniprot id: A0A0K2P5G6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1159554:AFK67 RS01030
gene id: 1159554:AFK67_RS01030
uniprot id: A0A0K2NX60
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

1159554:AFK67 RS07285
gene id: 1159554:AFK67_RS07285
uniprot id: A0A0K2P0N5
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.
messages: Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs.

1159554:AFK67 RS06605
gene id: 1159554:AFK67_RS06605
uniprot id: A0A0K2P032
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS12790
gene id: 1159554:AFK67_RS12790
uniprot id: A0A0K2P465
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1159554:AFK67 RS16380
gene id: 1159554:AFK67_RS16380
uniprot id: A0A0K2P5C8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1159554:AFK67 RS17475
gene id: 1159554:AFK67_RS17475
uniprot id: A0A0K2P6J7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CitD family.
messages: Covalent carrier of the coenzyme of citrate lyase.
messages: Cytoplasm
messages: Oligomer with a subunit composition of (alpha,beta,gamma)6.

1159554:AFK67 RS02465
gene id: 1159554:AFK67_RS02465
uniprot id: A0A0K2NY46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS08205
gene id: 1159554:AFK67_RS08205
uniprot id: A0A0K2P155
names: Similarity
messages: Belongs to the GST superfamily.

1159554:AFK67 RS19585
gene id: 1159554:AFK67_RS19585
uniprot id: A0A0K2P708
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1159554:AFK67 RS03880
gene id: 1159554:AFK67_RS03880
uniprot id: A0A0K2NYU2
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1159554:AFK67 RS08920
gene id: 1159554:AFK67_RS08920
uniprot id: A0A0K2P1J1
names: Function
names: Similarity
messages: Belongs to the GMC oxidoreductase family.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.

1159554:AFK67 RS07880
gene id: 1159554:AFK67_RS07880
uniprot id: A0A0K2P1J9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1159554:AFK67 RS08110
gene id: 1159554:AFK67_RS08110
uniprot id: A0A0K2P129
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1159554:AFK67 RS02395
gene id: 1159554:AFK67_RS02395
uniprot id: A0A0K2NXV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1159554:AFK67 RS19635
gene id: 1159554:AFK67_RS19635
uniprot id: A0A0K2P8N0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1159554:AFK67 RS03075
gene id: 1159554:AFK67_RS03075
uniprot id: A0A0K2NYD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

1159554:AFK67 RS13340
gene id: 1159554:AFK67_RS13340
uniprot id: A0A0K2P3Q7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.
messages: Cell inner membrane
messages: Part of a tripartite efflux system composed of MdtA, MdtB and MdtC. MdtB forms a heteromultimer with MdtC.

1159554:AFK67 RS06695
gene id: 1159554:AFK67_RS06695
uniprot id: A0A0K2P0W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

1159554:AFK67 RS00030
gene id: 1159554:AFK67_RS00030
uniprot id: A0A0K2NWM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1159554:AFK67 RS00265
gene id: 1159554:AFK67_RS00265
uniprot id: A0A0K2NWZ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1159554:AFK67 RS05055
gene id: 1159554:AFK67_RS05055
uniprot id: A0A0K2NZ98
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1159554:AFK67 RS21160
gene id: 1159554:AFK67_RS21160
uniprot id: A0A0K2P8Z7
names: Similarity
messages: Belongs to the MipA/OmpV family.

1159554:AFK67 RS03480
gene id: 1159554:AFK67_RS03480
uniprot id: A0A0K2NZ41
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

1159554:AFK67 RS09325
gene id: 1159554:AFK67_RS09325
uniprot id: A0A0K2P1J2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tus family.
messages: Cytoplasm
messages: Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence.

1159554:AFK67 RS18605
gene id: 1159554:AFK67_RS18605
uniprot id: A0A0K2P771
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

1159554:AFK67 RS14910
gene id: 1159554:AFK67_RS14910
uniprot id: A0A0K2P4M7
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1159554:AFK67 RS22350
gene id: 1159554:AFK67_RS22350
uniprot id: A0A0K2P705
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

1159554:AFK67 RS15195
gene id: 1159554:AFK67_RS15195
uniprot id: A0A0K2P5D9
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the maturation of IscU.

1159554:AFK67 RS16930
gene id: 1159554:AFK67_RS16930
uniprot id: A0A0K2P5K6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1159554:AFK67 RS19430
gene id: 1159554:AFK67_RS19430
uniprot id: A0A0K2P6W6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1159554:AFK67 RS11470
gene id: 1159554:AFK67_RS11470
uniprot id: A0A0K2P8H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1159554:AFK67 RS14495
gene id: 1159554:AFK67_RS14495
uniprot id: A0A0K2P4A6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1159554:AFK67 RS17955
gene id: 1159554:AFK67_RS17955
uniprot id: A0A0K2P666
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1159554:AFK67 RS02130
gene id: 1159554:AFK67_RS02130
uniprot id: A0A0K2NXY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

1159554:AFK67 RS05405
gene id: 1159554:AFK67_RS05405
uniprot id: A0A0K2NZN3
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the phosphorylation of guanosine and inosine to GMP and IMP, respectively.

1159554:AFK67 RS01940
gene id: 1159554:AFK67_RS01940
uniprot id: A0A0K2NYD4
names: Function
names: Similarity
messages: Belongs to the peptidase U62 family.
messages: Metalloprotease involved in CcdA degradation. Suppresses the inhibitory activity of the carbon storage regulator (CsrA).

1159554:AFK67 RS10870
gene id: 1159554:AFK67_RS10870
uniprot id: A0A0K2P2J9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1159554:AFK67 RS06305
gene id: 1159554:AFK67_RS06305
uniprot id: A0A0K2NZX6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

1159554:AFK67 RS09085
gene id: 1159554:AFK67_RS09085
uniprot id: A0A0K2P7R0
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1159554:AFK67 RS15020
gene id: 1159554:AFK67_RS15020
uniprot id: A0A0K2P4P0
names: Similarity
messages: Belongs to the ArsC family.

1159554:AFK67 RS14160
gene id: 1159554:AFK67_RS14160
uniprot id: A0A0K2P495
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1159554:AFK67 RS10630
gene id: 1159554:AFK67_RS10630
uniprot id: A0A0K2P2A9
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1159554:AFK67 RS08565
gene id: 1159554:AFK67_RS08565
uniprot id: A0A0K2P1W1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1159554:AFK67 RS18405
gene id: 1159554:AFK67_RS18405
uniprot id: A0A0K2P6D2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. DnaB subfamily.
messages: Homohexamer.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

1159554:AFK67 RS08420
gene id: 1159554:AFK67_RS08420
uniprot id: A0A0K2P126
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1159554:AFK67 RS13215
gene id: 1159554:AFK67_RS13215
uniprot id: A0A0K2P3R0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1159554:AFK67 RS03760
gene id: 1159554:AFK67_RS03760
uniprot id: A0A0K2NZA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.
messages: Membrane

1159554:AFK67 RS07450
gene id: 1159554:AFK67_RS07450
uniprot id: A0A0K2P1C8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1159554:AFK67 RS02535
gene id: 1159554:AFK67_RS02535
uniprot id: A0A0K2NXX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmG family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.

1159554:AFK67 RS06170
gene id: 1159554:AFK67_RS06170
uniprot id: A0A0K2P0J5
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

1159554:AFK67 RS19065
gene id: 1159554:AFK67_RS19065
uniprot id: A0A0K2P6V4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DamX family.
messages: Cell inner membrane
messages: Non-essential cell division protein.
messages: The SPOR domain binds septal peptidoglycans and is required to target DamX to the septal ring.

1159554:AFK67 RS19045
gene id: 1159554:AFK67_RS19045
uniprot id: A0A0K2P7E2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1159554:AFK67 RS05050
gene id: 1159554:AFK67_RS05050
uniprot id: A0A0K2NZG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Membrane

1159554:AFK67 RS12565
gene id: 1159554:AFK67_RS12565
uniprot id: A0A0K2P429
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1159554:AFK67 RS18115
gene id: 1159554:AFK67_RS18115
uniprot id: A0A0K2P6Y7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).

1159554:AFK67 RS15180
gene id: 1159554:AFK67_RS15180
uniprot id: A0A0K2P4N7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Probably plays an important role in intracellular peptide degradation.

1159554:AFK67 RS09255
gene id: 1159554:AFK67_RS09255
uniprot id: A0A0K2P1P4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1159554:AFK67 RS05965
gene id: 1159554:AFK67_RS05965
uniprot id: A0A0K2NZR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TatA/E family. TatE subfamily.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA.

1159554:AFK67 RS14915
gene id: 1159554:AFK67_RS14915
uniprot id: A0A0K2P578
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1159554:AFK67 RS07475
gene id: 1159554:AFK67_RS07475
uniprot id: A0A0K2P0S0
names: Similarity
messages: Belongs to the acylphosphatase family.

1159554:AFK67 RS18350
gene id: 1159554:AFK67_RS18350
uniprot id: A0A0K2P6C2
names: Function
names: Subunit
messages: Homotetramer.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1159554:AFK67 RS19170
gene id: 1159554:AFK67_RS19170
uniprot id: A0A0K2P6X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1159554:AFK67 RS16445
gene id: 1159554:AFK67_RS16445
uniprot id: A0A0K2P5F6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1159554:AFK67 RS20435
gene id: 1159554:AFK67_RS20435
uniprot id: A0A0K2P7G9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

1159554:AFK67 RS09800
gene id: 1159554:AFK67_RS09800
uniprot id: A0A0K2P209
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1159554:AFK67 RS01450
gene id: 1159554:AFK67_RS01450
uniprot id: A0A0K2NXL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

1159554:AFK67 RS14390
gene id: 1159554:AFK67_RS14390
uniprot id: A0A0K2P8K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

1159554:AFK67 RS19425
gene id: 1159554:AFK67_RS19425
uniprot id: A0A0K2P701
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

1159554:AFK67 RS06495
gene id: 1159554:AFK67_RS06495
uniprot id: A0A0K2P0R6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1159554:AFK67 RS14425
gene id: 1159554:AFK67_RS14425
uniprot id: A0A0K2P811
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.

1159554:AFK67 RS09970
gene id: 1159554:AFK67_RS09970
uniprot id: A0A0K2P2P7
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

1159554:AFK67 RS13385
gene id: 1159554:AFK67_RS13385
uniprot id: A0A0K2P3U0
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

1159554:AFK67 RS06795
gene id: 1159554:AFK67_RS06795
uniprot id: A0A0K2P0Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YkuD family.
messages: Periplasm

1159554:AFK67 RS17875
gene id: 1159554:AFK67_RS17875
uniprot id: A0A0K2P663
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

1159554:AFK67 RS10785
gene id: 1159554:AFK67_RS10785
uniprot id: A0A0K2P2B7
names: Function
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
messages: Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism and in the biotin biosynthesis.

1159554:AFK67 RS14030
gene id: 1159554:AFK67_RS14030
uniprot id: A0A0K2P469
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1159554:AFK67 RS01175
gene id: 1159554:AFK67_RS01175
uniprot id: A0A0K2NXG7
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1159554:AFK67 RS08750
gene id: 1159554:AFK67_RS08750
uniprot id: A0A0K2P1E3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1159554:AFK67 RS14360
gene id: 1159554:AFK67_RS14360
uniprot id: A0A0K2P4W9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1159554:AFK67 RS21245
gene id: 1159554:AFK67_RS21245
uniprot id: A0A0K2P8D6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1159554:AFK67 RS01210
gene id: 1159554:AFK67_RS01210
uniprot id: A0A0K2NXF4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1159554:AFK67 RS09975
gene id: 1159554:AFK67_RS09975
uniprot id: A0A0K2P229
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 37 family.
messages: Cytoplasm
messages: Hydrolyzes trehalose to glucose. Could be involved, in cells returning to low osmolarity conditions, in the utilization of the accumulated cytoplasmic trehalose, which was synthesized in response to high osmolarity.
messages: Monomer.

1159554:AFK67 RS15395
gene id: 1159554:AFK67_RS15395
uniprot id: A0A0K2P4Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1159554:AFK67 RS15495
gene id: 1159554:AFK67_RS15495
uniprot id: A0A0K2P4Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1159554:AFK67 RS09755
gene id: 1159554:AFK67_RS09755
uniprot id: A0A0K2P2L1
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

1159554:AFK67 RS03710
gene id: 1159554:AFK67_RS03710
uniprot id: A0A0K2NZ90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.

1159554:AFK67 RS20860
gene id: 1159554:AFK67_RS20860
uniprot id: A0A0K2P8A8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1159554:AFK67 RS06540
gene id: 1159554:AFK67_RS06540
uniprot id: A0A0K2P084
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

1159554:AFK67 RS18010
gene id: 1159554:AFK67_RS18010
uniprot id: A0A0K2P685
names: Cofactor
names: Function
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity.

1159554:AFK67 RS13150
gene id: 1159554:AFK67_RS13150
uniprot id: M9NH60
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1159554:AFK67 RS18710
gene id: 1159554:AFK67_RS18710
uniprot id: A0A0K2P6N8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1159554:AFK67 RS19465
gene id: 1159554:AFK67_RS19465
uniprot id: A0A0K2P731
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1159554:AFK67 RS02885
gene id: 1159554:AFK67_RS02885
uniprot id: A0A0K2NY39
names: Similarity
messages: Belongs to the glycosyl hydrolase 53 family.

1159554:AFK67 RS05290
gene id: 1159554:AFK67_RS05290
uniprot id: A0A0K2NZK2
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1159554:AFK67 RS12625
gene id: 1159554:AFK67_RS12625
uniprot id: A0A0K2P3D3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1159554:AFK67 RS06665
gene id: 1159554:AFK67_RS06665
uniprot id: A0A0K2P0B0
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS15630
gene id: 1159554:AFK67_RS15630
uniprot id: A0A0K2P507
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS06235
gene id: 1159554:AFK67_RS06235
uniprot id: A0A0K2NZY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1159554:AFK67 RS12255
gene id: 1159554:AFK67_RS12255
uniprot id: A0A0K2P398
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M23B family.
messages: Membrane

1159554:AFK67 RS15320
gene id: 1159554:AFK67_RS15320
uniprot id: A0A0K2P4X1
names: Function
names: Induction
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Induced by MurNAc 6-phosphate that releases the repressor MurR from the DNA. Repressed by MurR in the absence of MurNAc 6-phosphate.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

1159554:AFK67 RS17600
gene id: 1159554:AFK67_RS17600
uniprot id: A0A0K2P5Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

1159554:AFK67 RS11670
gene id: 1159554:AFK67_RS11670
uniprot id: A0A0K2P2S8
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS03975
gene id: 1159554:AFK67_RS03975
uniprot id: A0A0K2NYW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

1159554:AFK67 RS08450
gene id: 1159554:AFK67_RS08450
uniprot id: A0A0K2P152
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

1159554:AFK67 RS03670
gene id: 1159554:AFK67_RS03670
uniprot id: A0A0K2NYI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1159554:AFK67 RS02870
gene id: 1159554:AFK67_RS02870
uniprot id: A0A0K2NYB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins.
messages: Periplasm

1159554:AFK67 RS17075
gene id: 1159554:AFK67_RS17075
uniprot id: A0A0K2P5M6
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1159554:AFK67 RS07325
gene id: 1159554:AFK67_RS07325
uniprot id: A0A0K2P0H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Gram-negative porin family.
messages: Cell outer membrane
messages: Membrane

1159554:AFK67 RS01330
gene id: 1159554:AFK67_RS01330
uniprot id: A0A0K2NXH4
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

1159554:AFK67 RS04890
gene id: 1159554:AFK67_RS04890
uniprot id: A0A0K2NZY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell inner membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

1159554:AFK67 RS17070
gene id: 1159554:AFK67_RS17070
uniprot id: A0A0K2P5R4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1159554:AFK67 RS06155
gene id: 1159554:AFK67_RS06155
uniprot id: A0A0K2NZU6
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS20285
gene id: 1159554:AFK67_RS20285
uniprot id: A0A0K2P7D7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1159554:AFK67 RS10750
gene id: 1159554:AFK67_RS10750
uniprot id: A0A0K2P2G4
names: Similarity
messages: Belongs to the PspA/IM30 family.

1159554:AFK67 RS06735
gene id: 1159554:AFK67_RS06735
uniprot id: A0A0K2P086
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS16635
gene id: 1159554:AFK67_RS16635
uniprot id: A0A0K2P641
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

1159554:AFK67 RS14355
gene id: 1159554:AFK67_RS14355
uniprot id: A0A0K2P4C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS09425
gene id: 1159554:AFK67_RS09425
uniprot id: A0A0K2P1L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1159554:AFK67 RS04000
gene id: 1159554:AFK67_RS04000
uniprot id: A0A0K2NYT0
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1159554:AFK67 RS16270
gene id: 1159554:AFK67_RS16270
uniprot id: A0A0K2P8L4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1159554:AFK67 RS15235
gene id: 1159554:AFK67_RS15235
uniprot id: A0A0K2P4Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family. RcnA subfamily.
messages: Cell membrane
messages: Efflux system for nickel and cobalt.
messages: Membrane

1159554:AFK67 RS19900
gene id: 1159554:AFK67_RS19900
uniprot id: A0A0K2P770
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyltransferase 3 family.
messages: Cell inner membrane
messages: Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units.

1159554:AFK67 RS13420
gene id: 1159554:AFK67_RS13420
uniprot id: A0A0K2P3S2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

1159554:AFK67 RS15400
gene id: 1159554:AFK67_RS15400
uniprot id: A0A0K2P5J1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

1159554:AFK67 RS06030
gene id: 1159554:AFK67_RS06030
uniprot id: A0A0K2P0H3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

1159554:AFK67 RS04355
gene id: 1159554:AFK67_RS04355
uniprot id: A0A0K2NYZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

1159554:AFK67 RS00220
gene id: 1159554:AFK67_RS00220
uniprot id: A0A0K2NWR1
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

1159554:AFK67 RS19345
gene id: 1159554:AFK67_RS19345
uniprot id: A0A0K2P6V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1159554:AFK67 RS03755
gene id: 1159554:AFK67_RS03755
uniprot id: A0A0K2NYT1
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1159554:AFK67 RS07860
gene id: 1159554:AFK67_RS07860
uniprot id: A0A0K2P0Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1159554:AFK67 RS04610
gene id: 1159554:AFK67_RS04610
uniprot id: A0A0K2NZ79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1159554:AFK67 RS13400
gene id: 1159554:AFK67_RS13400
uniprot id: A0A0K2P3W4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1159554:AFK67 RS08780
gene id: 1159554:AFK67_RS08780
uniprot id: A0A0K2P194
names: Similarity
messages: Belongs to the HypE family.

1159554:AFK67 RS05375
gene id: 1159554:AFK67_RS05375
uniprot id: A0A0K2NZI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Molecular chaperone. Has ATPase activity.

1159554:AFK67 RS02490
gene id: 1159554:AFK67_RS02490
uniprot id: A0A0K2NXZ9
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS05115
gene id: 1159554:AFK67_RS05115
uniprot id: A0A0K2NZI2
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1159554:AFK67 RS17295
gene id: 1159554:AFK67_RS17295
uniprot id: A0A0K2P5V7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS20535
gene id: 1159554:AFK67_RS20535
uniprot id: A0A0K2P7I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

1159554:AFK67 RS04280
gene id: 1159554:AFK67_RS04280
uniprot id: A0A0K2NYW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
messages: Cell membrane
messages: Homotetramer.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine.

1159554:AFK67 RS19490
gene id: 1159554:AFK67_RS19490
uniprot id: A0A0K2P736
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. YhhS family.
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS16150
gene id: 1159554:AFK67_RS16150
uniprot id: A0A0K2P5B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS07185
gene id: 1159554:AFK67_RS07185
uniprot id: A0A0K2P180
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

1159554:AFK67 RS15460
gene id: 1159554:AFK67_RS15460
uniprot id: A0A0K2P4U0
names: Similarity
messages: Belongs to the TPP enzyme family.

1159554:AFK67 RS15145
gene id: 1159554:AFK67_RS15145
uniprot id: A0A0K2P5C9
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS19250
gene id: 1159554:AFK67_RS19250
uniprot id: A0A0K2P6U4
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1159554:AFK67 RS11585
gene id: 1159554:AFK67_RS11585
uniprot id: A0A0K2P2R3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

1159554:AFK67 RS16520
gene id: 1159554:AFK67_RS16520
uniprot id: A0A0K2P5H2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS00865
gene id: 1159554:AFK67_RS00865
uniprot id: A0A0K2P7N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1159554:AFK67 RS06465
gene id: 1159554:AFK67_RS06465
uniprot id: A0A0K2P069
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1159554:AFK67 RS09580
gene id: 1159554:AFK67_RS09580
uniprot id: A0A0K2P2F6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1159554:AFK67 RS10260
gene id: 1159554:AFK67_RS10260
uniprot id: A0A0K2P292
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1159554:AFK67 RS00880
gene id: 1159554:AFK67_RS00880
uniprot id: A0A0K2NXA0
names: Similarity
messages: Belongs to the glycosyl hydrolase.

1159554:AFK67 RS06750
gene id: 1159554:AFK67_RS06750
uniprot id: A0A0K2P0C5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Dps family.
messages: Cytoplasm
messages: During stationary phase, binds the chromosome non-specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction.
messages: Homododecamer. The 12 subunits form a hollow sphere into which the mineral iron core of up to 500 Fe(3+) can be deposited.

1159554:AFK67 RS06345
gene id: 1159554:AFK67_RS06345
uniprot id: A0A0K2P0N6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1159554:AFK67 RS11740
gene id: 1159554:AFK67_RS11740
uniprot id: A0A0K2P2Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0266 family.
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS17605
gene id: 1159554:AFK67_RS17605
uniprot id: A0A0K2P629
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally stabilizes TonB.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

1159554:AFK67 RS06970
gene id: 1159554:AFK67_RS06970
uniprot id: A0A0K2P0A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1159554:AFK67 RS09485
gene id: 1159554:AFK67_RS09485
uniprot id: A0A0K2P1T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1159554:AFK67 RS01595
gene id: 1159554:AFK67_RS01595
uniprot id: A0A0K2NXN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

1159554:AFK67 RS16410
gene id: 1159554:AFK67_RS16410
uniprot id: A0A0K2P5A1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1159554:AFK67 RS18840
gene id: 1159554:AFK67_RS18840
uniprot id: A0A0K2P7A7
names: Similarity
messages: Belongs to the peptidase A24 family.

1159554:AFK67 RS03965
gene id: 1159554:AFK67_RS03965
uniprot id: A0A0K2NYP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation.
messages: Homodimer.

1159554:AFK67 RS03915
gene id: 1159554:AFK67_RS03915
uniprot id: A0A0K2NYN7
names: Function
names: Similarity
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

1159554:AFK67 RS07560
gene id: 1159554:AFK67_RS07560
uniprot id: A0A0K2P1E6
names: Function
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family. RutF subfamily.
messages: Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway.

1159554:AFK67 RS10935
gene id: 1159554:AFK67_RS10935
uniprot id: A0A0K2P2J7
names: Function
names: Similarity
messages: Belongs to the TrpC family.
messages: Belongs to the TrpF family.
messages: Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain.
messages: In the C-terminal section; belongs to the TrpF family.
messages: In the N-terminal section; belongs to the TrpC family.

1159554:AFK67 RS13620
gene id: 1159554:AFK67_RS13620
uniprot id: A0A0K2P4K2
names: Similarity
messages: Belongs to the elongation factor P family.

1159554:AFK67 RS18665
gene id: 1159554:AFK67_RS18665
uniprot id: A0A0K2P6L2
names: Similarity
messages: Belongs to the DprA/Smf family.

1159554:AFK67 RS10250
gene id: 1159554:AFK67_RS10250
uniprot id: A0A0K2P216
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1159554:AFK67 RS03230
gene id: 1159554:AFK67_RS03230
uniprot id: A0A0K2NYZ6
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. GpmB subfamily.

1159554:AFK67 RS12535
gene id: 1159554:AFK67_RS12535
uniprot id: A0A0K2P3G6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1159554:AFK67 RS13700
gene id: 1159554:AFK67_RS13700
uniprot id: A0A0K2P4L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

1159554:AFK67 RS17735
gene id: 1159554:AFK67_RS17735
uniprot id: A0A0K2P653
names: Function
names: Similarity
messages: Belongs to the peptidase U62 family.
messages: Metalloprotease involved in CcdA degradation. Suppresses the inhibitory activity of the carbon storage regulator (CsrA).

1159554:AFK67 RS18595
gene id: 1159554:AFK67_RS18595
uniprot id: A0A0K2P6H9
names: Cofactor
messages: Can also use Mn(2+) ion.

1159554:AFK67 RS03375
gene id: 1159554:AFK67_RS03375
uniprot id: A0A0K2NYK4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1159554:AFK67 RS15535
gene id: 1159554:AFK67_RS15535
uniprot id: A0A0K2P4U8
names: Subcellular Location Annotation
messages: Cytoplasm

1159554:AFK67 RS17575
gene id: 1159554:AFK67_RS17575
uniprot id: A0A0K2P5Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0114 family.
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS04030
gene id: 1159554:AFK67_RS04030
uniprot id: A0A0K2NYT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1159554:AFK67 RS11240
gene id: 1159554:AFK67_RS11240
uniprot id: A0A0K2P2K6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1159554:AFK67 RS20110
gene id: 1159554:AFK67_RS20110
uniprot id: A0A0K2P7A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1159554:AFK67 RS08145
gene id: 1159554:AFK67_RS08145
uniprot id: A0A0K2P101
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell membrane
messages: Cytoplasm

1159554:AFK67 RS20950
gene id: 1159554:AFK67_RS20950
uniprot id: A0A0K2P8B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

1159554:AFK67 RS13745
gene id: 1159554:AFK67_RS13745
uniprot id: A0A0K2P800
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS20095
gene id: 1159554:AFK67_RS20095
uniprot id: A0A0K2P7Y6
names: Subcellular Location Annotation
messages: Cell inner membrane

1159554:AFK67 RS06580
gene id: 1159554:AFK67_RS06580
uniprot id: A0A0K2P028
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

1159554:AFK67 RS14995
gene id: 1159554:AFK67_RS14995
uniprot id: A0A0K2P4N5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1159554:AFK67 RS01230
gene id: 1159554:AFK67_RS01230
uniprot id: A0A0K2NXY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

1159554:AFK67 RS05980
gene id: 1159554:AFK67_RS05980
uniprot id: A0A0K2P0G4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1159554:AFK67 RS19010
gene id: 1159554:AFK67_RS19010
uniprot id: A0A0K2P6Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

1159554:AFK67 RS06850
gene id: 1159554:AFK67_RS06850
uniprot id: A0A0K2P0Z4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

1159554:AFK67 RS09810
gene id: 1159554:AFK67_RS09810
uniprot id: A0A0K2P200
names: Similarity
messages: Belongs to the VgrG protein family.

1159554:AFK67 RS15100
gene id: 1159554:AFK67_RS15100
uniprot id: A0A0K2P4M1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1159554:AFK67 RS18395
gene id: 1159554:AFK67_RS18395
uniprot id: A0A0K2P733
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1159554:AFK67 RS19435
gene id: 1159554:AFK67_RS19435
uniprot id: A0A0K2P6X9
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

1159554:AFK67 RS00920
gene id: 1159554:AFK67_RS00920
uniprot id: A0A0K2NX41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L-rhamnose transporter (TC 2.A.7.6) family.
messages: Cell membrane
messages: Uptake of L-rhamnose across the cytoplasmic membrane with the concomitant transport of protons into the cell (symport system).

1159554:AFK67 RS17835
gene id: 1159554:AFK67_RS17835
uniprot id: A0A0K2P644
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.

1159554:AFK67 RS03715
gene id: 1159554:AFK67_RS03715
uniprot id: A0A0K2NYR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1159554:AFK67 RS15125
gene id: 1159554:AFK67_RS15125
uniprot id: A0A0K2P4M6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

1159554:AFK67 RS11255
gene id: 1159554:AFK67_RS11255
uniprot id: A0A0K2P2R7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
messages: Homodimer.

1159554:AFK67 RS00900
gene id: 1159554:AFK67_RS00900
uniprot id: A0A0K2NXC1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the rhamnose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
messages: Cytoplasm
messages: Homotetramer.

1159554:AFK67 RS19455
gene id: 1159554:AFK67_RS19455
uniprot id: A0A0K2P6X0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1159554:AFK67 RS04660
gene id: 1159554:AFK67_RS04660
uniprot id: A0A0K2NZ87
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

1159554:AFK67 RS13435
gene id: 1159554:AFK67_RS13435
uniprot id: A0A0K2P3V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1159554:AFK67 RS02175
gene id: 1159554:AFK67_RS02175
uniprot id: A0A0K2NXU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

1159554:AFK67 RS19495
gene id: 1159554:AFK67_RS19495
uniprot id: A0A0K2P7L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1159554:AFK67 RS04955
gene id: 1159554:AFK67_RS04955
uniprot id: A0A0K2NZ78
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1159554:AFK67 RS02170
gene id: 1159554:AFK67_RS02170
uniprot id: A0A0K2NXR1
names: Similarity
messages: Belongs to the BolA/IbaG family.

1159554:AFK67 RS15185
gene id: 1159554:AFK67_RS15185
uniprot id: A0A0K2P4N3
names: Function
names: Similarity
messages: Belongs to the IscX family.
messages: May function as iron donor in the assembly of iron-sulfur clusters.

1159554:AFK67 RS16370
gene id: 1159554:AFK67_RS16370
uniprot id: A0A0K2P5E5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

1159554:AFK67 RS14410
gene id: 1159554:AFK67_RS14410
uniprot id: A0A0K2P491
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS14945
gene id: 1159554:AFK67_RS14945
uniprot id: A0A0K2P4M4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1159554:AFK67 RS07900
gene id: 1159554:AFK67_RS07900
uniprot id: A0A0K2P0Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

1159554:AFK67 RS03290
gene id: 1159554:AFK67_RS03290
uniprot id: A0A0K2NYA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS05885
gene id: 1159554:AFK67_RS05885
uniprot id: A0A0K2NZV9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1159554:AFK67 RS10545
gene id: 1159554:AFK67_RS10545
uniprot id: A0A0K2P2E3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

1159554:AFK67 RS05990
gene id: 1159554:AFK67_RS05990
uniprot id: A0A0K2NZR9
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1159554:AFK67 RS07945
gene id: 1159554:AFK67_RS07945
uniprot id: A0A0K2P0W1
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

1159554:AFK67 RS02635
gene id: 1159554:AFK67_RS02635
uniprot id: A0A0K2NY61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraB family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
messages: Interacts with the C-terminal region of Rne.

1159554:AFK67 RS09695
gene id: 1159554:AFK67_RS09695
uniprot id: A0A0K2P1T5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1159554:AFK67 RS14100
gene id: 1159554:AFK67_RS14100
uniprot id: A0A0K2P430
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

1159554:AFK67 RS15340
gene id: 1159554:AFK67_RS15340
uniprot id: A0A0K2P4S3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1159554:AFK67 RS07130
gene id: 1159554:AFK67_RS07130
uniprot id: A0A0K2P0K7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1159554:AFK67 RS09245
gene id: 1159554:AFK67_RS09245
uniprot id: A0A0K2P1H6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1159554:AFK67 RS04965
gene id: 1159554:AFK67_RS04965
uniprot id: A0A0K2NZF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

1159554:AFK67 RS14820
gene id: 1159554:AFK67_RS14820
uniprot id: A0A0K2P4K0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS10265
gene id: 1159554:AFK67_RS10265
uniprot id: A0A0K2P2U7
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1159554:AFK67 RS02070
gene id: 1159554:AFK67_RS02070
uniprot id: A0A0K2NXT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

1159554:AFK67 RS19275
gene id: 1159554:AFK67_RS19275
uniprot id: A0A0K2P6U7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1159554:AFK67 RS09225
gene id: 1159554:AFK67_RS09225
uniprot id: A0A0K2P8F5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family. DtpA subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton-dependent permease that transports di- and tripeptides.

1159554:AFK67 RS01925
gene id: 1159554:AFK67_RS01925
uniprot id: A0A0K2NXM7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1159554:AFK67 RS13965
gene id: 1159554:AFK67_RS13965
uniprot id: A0A0K2P441
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

1159554:AFK67 RS18555
gene id: 1159554:AFK67_RS18555
uniprot id: A0A0K2P761
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1159554:AFK67 RS09420
gene id: 1159554:AFK67_RS09420
uniprot id: A0A0K2P1R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1159554:AFK67 RS09110
gene id: 1159554:AFK67_RS09110
uniprot id: A0A0K2P1H4
names: Domain
names: Function
names: Subunit
messages: Consists of two structural and functional domains: an N-terminal DNA-binding domain, approximately the first 60 residues, and a larger C-terminal domain, approximately 280 residues, which imparts the function of corepressor binding and oligomerization.
messages: Homodimer.
messages: Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.

1159554:AFK67 RS08010
gene id: 1159554:AFK67_RS08010
uniprot id: A0A0K2P109
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1159554:AFK67 RS20800
gene id: 1159554:AFK67_RS20800
uniprot id: A0A0K2P8T7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1159554:AFK67 RS22935
gene id: 1159554:AFK67_RS22935
uniprot id: A0A0K2P4K9
names: Cofactor
messages: Binds 1 phosphopantetheine covalently.

1159554:AFK67 RS03785
gene id: 1159554:AFK67_RS03785
uniprot id: A0A0K2P8C0
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1159554:AFK67 RS20080
gene id: 1159554:AFK67_RS20080
uniprot id: A0A0K2P796
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. FieF subfamily.
messages: Cell inner membrane
messages: Divalent metal cation transporter which exports Zn(2+), Cd(2+) and possibly Fe(2+). May be involved in zinc and iron detoxification by efflux.
messages: Homodimer.
messages: Membrane

1159554:AFK67 RS14760
gene id: 1159554:AFK67_RS14760
uniprot id: A0A0K2P545
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

1159554:AFK67 RS01075
gene id: 1159554:AFK67_RS01075
uniprot id: A0A0K2NXD5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M20A family. ArgE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of the amide bond of N(2)-acetylated L-amino acids. Cleaves the acetyl group from N-acetyl-L-ornithine to form L-ornithine, an intermediate in L-arginine biosynthesis pathway, and a branchpoint in the synthesis of polyamines.
messages: Cytoplasm
messages: Homodimer.

1159554:AFK67 RS07955
gene id: 1159554:AFK67_RS07955
uniprot id: A0A0K2P1L2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1159554:AFK67 RS05855
gene id: 1159554:AFK67_RS05855
uniprot id: A0A0K2P0E3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).

1159554:AFK67 RS04975
gene id: 1159554:AFK67_RS04975
uniprot id: A0A0K2NZE6
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1159554:AFK67 RS12880
gene id: 1159554:AFK67_RS12880
uniprot id: A0A0K2P3K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Gram-negative porin family.
messages: Cell outer membrane
messages: Membrane

1159554:AFK67 RS01465
gene id: 1159554:AFK67_RS01465
uniprot id: A0A0K2NXD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
messages: Cytoplasm

1159554:AFK67 RS08045
gene id: 1159554:AFK67_RS08045
uniprot id: A0A0K2P0Y1
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1159554:AFK67 RS04810
gene id: 1159554:AFK67_RS04810
uniprot id: A0A0K2NZX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS01540
gene id: 1159554:AFK67_RS01540
uniprot id: A0A0K2NXF5
names: Function
names: Similarity
names: Subunit
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).
messages: In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
messages: Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.

1159554:AFK67 RS17365
gene id: 1159554:AFK67_RS17365
uniprot id: A0A0K2P5Y4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1159554:AFK67 RS01945
gene id: 1159554:AFK67_RS01945
uniprot id: A0A0K2NXT7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1159554:AFK67 RS08925
gene id: 1159554:AFK67_RS08925
uniprot id: A0A0K2P232
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Binds 2 potassium ions per subunit.
messages: Dimer of dimers.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1159554:AFK67 RS04995
gene id: 1159554:AFK67_RS04995
uniprot id: A0A0K2P007
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1159554:AFK67 RS03595
gene id: 1159554:AFK67_RS03595
uniprot id: A0A0K2NYH3
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1159554:AFK67 RS14235
gene id: 1159554:AFK67_RS14235
uniprot id: A0A0K2P458
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0208 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS06550
gene id: 1159554:AFK67_RS06550
uniprot id: A0A0K2P081
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1159554:AFK67 RS02510
gene id: 1159554:AFK67_RS02510
uniprot id: A0A0K2NXX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
messages: Membrane

1159554:AFK67 RS15050
gene id: 1159554:AFK67_RS15050
uniprot id: A0A0K2P4L0
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1159554:AFK67 RS12915
gene id: 1159554:AFK67_RS12915
uniprot id: A0A0K2P3I2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1159554:AFK67 RS20995
gene id: 1159554:AFK67_RS20995
uniprot id: A0A0K2P8D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1159554:AFK67 RS03415
gene id: 1159554:AFK67_RS03415
uniprot id: A0A0K2NYD5
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1159554:AFK67 RS09235
gene id: 1159554:AFK67_RS09235
uniprot id: A0A0K2P290
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1159554:AFK67 RS11235
gene id: 1159554:AFK67_RS11235
uniprot id: A0A0K2P2P9
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1159554:AFK67 RS04300
gene id: 1159554:AFK67_RS04300
uniprot id: A0A0K2NZL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1159554:AFK67 RS06165
gene id: 1159554:AFK67_RS06165
uniprot id: A0A0K2P010
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1159554:AFK67 RS03570
gene id: 1159554:AFK67_RS03570
uniprot id: A0A0K2NYG8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1159554:AFK67 RS08390
gene id: 1159554:AFK67_RS08390
uniprot id: A0A0K2P121
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

1159554:AFK67 RS14485
gene id: 1159554:AFK67_RS14485
uniprot id: A0A0K2P4E4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

1159554:AFK67 RS11555
gene id: 1159554:AFK67_RS11555
uniprot id: A0A0K2P2V0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.
messages: Cell membrane
messages: K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels.

1159554:AFK67 RS09115
gene id: 1159554:AFK67_RS09115
uniprot id: A0A0K2P1L9
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS03490
gene id: 1159554:AFK67_RS03490
uniprot id: A0A0K2NYF0
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
messages: The transmembrane domain is a dimerization domain.

1159554:AFK67 RS12820
gene id: 1159554:AFK67_RS12820
uniprot id: A0A0K2P3J3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1159554:AFK67 RS18100
gene id: 1159554:AFK67_RS18100
uniprot id: A0A0K2P683
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

1159554:AFK67 RS07445
gene id: 1159554:AFK67_RS07445
uniprot id: A0A0K2P0R5
names: Subcellular Location Annotation
messages: Cell inner membrane

1159554:AFK67 RS11510
gene id: 1159554:AFK67_RS11510
uniprot id: A0A0K2P2P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1159554:AFK67 RS19225
gene id: 1159554:AFK67_RS19225
uniprot id: A0A0K2P6Y6
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS05015
gene id: 1159554:AFK67_RS05015
uniprot id: A0A0K2NZG3
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1159554:AFK67 RS02410
gene id: 1159554:AFK67_RS02410
uniprot id: A0A0K2NY36
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1159554:AFK67 RS05970
gene id: 1159554:AFK67_RS05970
uniprot id: A0A0K2NZT8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1159554:AFK67 RS02420
gene id: 1159554:AFK67_RS02420
uniprot id: A0A0K2NY21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

1159554:AFK67 RS17275
gene id: 1159554:AFK67_RS17275
uniprot id: A0A0K2P5S0
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

1159554:AFK67 RS01995
gene id: 1159554:AFK67_RS01995
uniprot id: A0A0K2NXU7
names: Similarity
messages: Belongs to the peptidase S1C family.

1159554:AFK67 RS01560
gene id: 1159554:AFK67_RS01560
uniprot id: A0A0K2NXL4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HemG family.
messages: Belongs to the flavodoxin family.
messages: Binds 1 FMN non-covalently per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX; under anaerobic conditions uses menaquinone as an electron acceptor, under aerobic conditions uses ubiquinone as an electron acceptor.
messages: Cell membrane

1159554:AFK67 RS13515
gene id: 1159554:AFK67_RS13515
uniprot id: A0A0K2P3W6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion.
messages: Homodimer.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1159554:AFK67 RS18825
gene id: 1159554:AFK67_RS18825
uniprot id: A0A0K2P6K6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1159554:AFK67 RS07640
gene id: 1159554:AFK67_RS07640
uniprot id: A0A0K2P1F9
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1159554:AFK67 RS17815
gene id: 1159554:AFK67_RS17815
uniprot id: A0A0K2P664
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

1159554:AFK67 RS02585
gene id: 1159554:AFK67_RS02585
uniprot id: A0A0K2NY51
names: Similarity
names: Subunit
messages: Belongs to the RutC family.
messages: Homotrimer.

1159554:AFK67 RS12865
gene id: 1159554:AFK67_RS12865
uniprot id: A0A0K2P3M3
names: Function
names: Similarity
messages: Belongs to the vsr family.
messages: May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.

1159554:AFK67 RS06435
gene id: 1159554:AFK67_RS06435
uniprot id: A0A0K2P022
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

1159554:AFK67 RS01950
gene id: 1159554:AFK67_RS01950
uniprot id: A0A0K2NXN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AaeX family.
messages: Cell membrane

1159554:AFK67 RS06315
gene id: 1159554:AFK67_RS06315
uniprot id: A0A0K2P041
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

1159554:AFK67 RS16400
gene id: 1159554:AFK67_RS16400
uniprot id: A0A0K2P5Z7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

1159554:AFK67 RS04650
gene id: 1159554:AFK67_RS04650
uniprot id: A0A0K2NZ99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family. LpxP subfamily.
messages: Catalyzes the transfer of palmitoleate from palmitoleoyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(palmitoleoyl)-lipid IV(A).
messages: Cell inner membrane

1159554:AFK67 RS02675
gene id: 1159554:AFK67_RS02675
uniprot id: A0A0K2NY81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1159554:AFK67 RS12510
gene id: 1159554:AFK67_RS12510
uniprot id: A0A0K2P3G1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS05360
gene id: 1159554:AFK67_RS05360
uniprot id: A0A0K2P068
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1159554:AFK67 RS03900
gene id: 1159554:AFK67_RS03900
uniprot id: A0A0K2NYV5
names: Similarity
messages: Belongs to the SfsA family.

1159554:AFK67 RS17045
gene id: 1159554:AFK67_RS17045
uniprot id: A0A0K2P5Q9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1159554:AFK67 RS12055
gene id: 1159554:AFK67_RS12055
uniprot id: A0A0K2P345
names: Function
names: Similarity
names: Subunit
messages: Belongs to the rusA family.
messages: Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of CC dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of RuvAB or RuvC.
messages: Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC.
messages: Homodimer.

1159554:AFK67 RS00745
gene id: 1159554:AFK67_RS00745
uniprot id: A0A0K2NX77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1159554:AFK67 RS05595
gene id: 1159554:AFK67_RS05595
uniprot id: A0A0K2P7T5
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS03370
gene id: 1159554:AFK67_RS03370
uniprot id: A0A0K2NYF9
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

1159554:AFK67 RS12225
gene id: 1159554:AFK67_RS12225
uniprot id: A0A0K2P347
names: Similarity
names: Subunit
messages: Belongs to the KHG/KDPG aldolase family.
messages: Homotrimer.

1159554:AFK67 RS20975
gene id: 1159554:AFK67_RS20975
uniprot id: A0A0K2P8C3
names: Similarity
messages: Belongs to the IucA/IucC family.

1159554:AFK67 RS12275
gene id: 1159554:AFK67_RS12275
uniprot id: A0A0K2P358
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1159554:AFK67 RS05420
gene id: 1159554:AFK67_RS05420
uniprot id: A0A0K2NZG7
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1159554:AFK67 RS16685
gene id: 1159554:AFK67_RS16685
uniprot id: A0A0K2P648
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

1159554:AFK67 RS04135
gene id: 1159554:AFK67_RS04135
uniprot id: A0A0K2NYZ7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1159554:AFK67 RS10705
gene id: 1159554:AFK67_RS10705
uniprot id: A0A0K2P2A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1159554:AFK67 RS08300
gene id: 1159554:AFK67_RS08300
uniprot id: A0A0K2P107
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS16580
gene id: 1159554:AFK67_RS16580
uniprot id: A0A0K2P5G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1159554:AFK67 RS08600
gene id: 1159554:AFK67_RS08600
uniprot id: A0A0K2P157
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1159554:AFK67 RS02285
gene id: 1159554:AFK67_RS02285
uniprot id: A0A0K2NXT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1159554:AFK67 RS01305
gene id: 1159554:AFK67_RS01305
uniprot id: A0A0K2NY00
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS17100
gene id: 1159554:AFK67_RS17100
uniprot id: A0A0K2P5N2
names: Similarity
messages: Belongs to the GSP E family.

1159554:AFK67 RS05005
gene id: 1159554:AFK67_RS05005
uniprot id: A0A0K2NZ88
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1159554:AFK67 RS10255
gene id: 1159554:AFK67_RS10255
uniprot id: A0A0K2P240
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1159554:AFK67 RS11250
gene id: 1159554:AFK67_RS11250
uniprot id: A0A0K2P2L8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.
messages: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.

1159554:AFK67 RS14600
gene id: 1159554:AFK67_RS14600
uniprot id: A0A0K2P4H1
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS16655
gene id: 1159554:AFK67_RS16655
uniprot id: A0A0K2P5J6
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS03805
gene id: 1159554:AFK67_RS03805
uniprot id: A0A0K2NYS9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

1159554:AFK67 RS12620
gene id: 1159554:AFK67_RS12620
uniprot id: A0A0K2P3C2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Cell inner membrane
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

1159554:AFK67 RS16515
gene id: 1159554:AFK67_RS16515
uniprot id: A0A0K2P5C5
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

1159554:AFK67 RS07205
gene id: 1159554:AFK67_RS07205
uniprot id: A0A0K2P0M1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.

1159554:AFK67 RS04140
gene id: 1159554:AFK67_RS04140
uniprot id: A0A0K2NZI4
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

1159554:AFK67 RS08585
gene id: 1159554:AFK67_RS08585
uniprot id: A0A0K2P1C4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1159554:AFK67 RS19630
gene id: 1159554:AFK67_RS19630
uniprot id: A0A0K2P710
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

1159554:AFK67 RS09240
gene id: 1159554:AFK67_RS09240
uniprot id: A0A0K2P1M8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1159554:AFK67 RS19775
gene id: 1159554:AFK67_RS19775
uniprot id: A0A0K2P7R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS02140
gene id: 1159554:AFK67_RS02140
uniprot id: A0A0K2NXX2
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS16360
gene id: 1159554:AFK67_RS16360
uniprot id: A0A0K2P591
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS04125
gene id: 1159554:AFK67_RS04125
uniprot id: A0A0K2NYT6
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1159554:AFK67 RS09985
gene id: 1159554:AFK67_RS09985
uniprot id: A0A0K2P1Z2
names: Similarity
messages: Belongs to the mannitol dehydrogenase family. UxaB subfamily.

1159554:AFK67 RS03410
gene id: 1159554:AFK67_RS03410
uniprot id: A0A0K2NYK2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1159554:AFK67 RS12245
gene id: 1159554:AFK67_RS12245
uniprot id: A0A0K2P339
names: Similarity
messages: Belongs to the pyruvate kinase family.

1159554:AFK67 RS01800
gene id: 1159554:AFK67_RS01800
uniprot id: A0A0K2NXT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS09130
gene id: 1159554:AFK67_RS09130
uniprot id: A0A0K2P1F6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

1159554:AFK67 RS16510
gene id: 1159554:AFK67_RS16510
uniprot id: A0A0K2P5C1
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1159554:AFK67 RS06935
gene id: 1159554:AFK67_RS06935
uniprot id: A0A0K2P111
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family. YbjL subfamily.
messages: Cell membrane

1159554:AFK67 RS04925
gene id: 1159554:AFK67_RS04925
uniprot id: A0A0K2P7N6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1159554:AFK67 RS01715
gene id: 1159554:AFK67_RS01715
uniprot id: A0A0K2NXS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rsd/AlgQ family.
messages: Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase.
messages: Cytoplasm
messages: Interacts with RpoD.

1159554:AFK67 RS15525
gene id: 1159554:AFK67_RS15525
uniprot id: A0A0K2P5K9
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1159554:AFK67 RS01555
gene id: 1159554:AFK67_RS01555
uniprot id: A0A0K2NY53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

1159554:AFK67 RS13930
gene id: 1159554:AFK67_RS13930
uniprot id: A0A0K2P7W0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1159554:AFK67 RS06260
gene id: 1159554:AFK67_RS06260
uniprot id: A0A0K2NZZ0
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.

1159554:AFK67 RS14855
gene id: 1159554:AFK67_RS14855
uniprot id: A0A0K2P4G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1159554:AFK67 RS03355
gene id: 1159554:AFK67_RS03355
uniprot id: A0A0K2NZ16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1159554:AFK67 RS00380
gene id: 1159554:AFK67_RS00380
uniprot id: A0A0K2NX38
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1159554:AFK67 RS20235
gene id: 1159554:AFK67_RS20235
uniprot id: A0A0K2P7D3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1159554:AFK67 RS19870
gene id: 1159554:AFK67_RS19870
uniprot id: A0A0K2P754
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily.
messages: Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
messages: Cytoplasm
messages: Homodimer.

1159554:AFK67 RS10405
gene id: 1159554:AFK67_RS10405
uniprot id: A0A0K2P269
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS14115
gene id: 1159554:AFK67_RS14115
uniprot id: A0A0K2P4S9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

1159554:AFK67 RS07430
gene id: 1159554:AFK67_RS07430
uniprot id: A0A0K2P0Q7
names: Function
names: Induction
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the SulA family.
messages: By DNA damage, as part of the SOS response.
messages: Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
messages: Interacts with FtsZ.
messages: Is rapidly cleaved and degraded by the Lon protease once DNA damage is repaired.

1159554:AFK67 RS16180
gene id: 1159554:AFK67_RS16180
uniprot id: A0A0K2P5W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1159554:AFK67 RS02450
gene id: 1159554:AFK67_RS02450
uniprot id: A0A0K2NY25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1159554:AFK67 RS14245
gene id: 1159554:AFK67_RS14245
uniprot id: A0A0K2P4B0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

1159554:AFK67 RS07730
gene id: 1159554:AFK67_RS07730
uniprot id: A0A0K2P1H2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YmdB family.
messages: Deacetylates O-acetyl-ADP ribose to yield ADP-ribose and free acetate. Down-regulates ribonuclease 3 (RNase III) activity. Acts by interacting directly with the region of the ribonuclease that is required for dimerization/activation.
messages: Homodimer. Interacts with RNase III.

1159554:AFK67 RS17035
gene id: 1159554:AFK67_RS17035
uniprot id: A0A0K2P5S1
names: Function
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.
messages: Catalyzes the formation of putrescine from agmatine.

1159554:AFK67 RS09460
gene id: 1159554:AFK67_RS09460
uniprot id: A0A0K2P1T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1159554:AFK67 RS13595
gene id: 1159554:AFK67_RS13595
uniprot id: A0A0K2P4J7
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

1159554:AFK67 RS14105
gene id: 1159554:AFK67_RS14105
uniprot id: A0A0K2P438
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1159554:AFK67 RS15225
gene id: 1159554:AFK67_RS15225
uniprot id: A0A0K2P4T9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

1159554:AFK67 RS06600
gene id: 1159554:AFK67_RS06600
uniprot id: A0A0K2P093
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1159554:AFK67 RS14165
gene id: 1159554:AFK67_RS14165
uniprot id: A0A0K2P4T8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1159554:AFK67 RS17370
gene id: 1159554:AFK67_RS17370
uniprot id: A0A0K2P6H3
names: Similarity
messages: Belongs to the UDP-glycosyltransferase family.

1159554:AFK67 RS14740
gene id: 1159554:AFK67_RS14740
uniprot id: A0A0K2P4I5
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1159554:AFK67 RS07890
gene id: 1159554:AFK67_RS07890
uniprot id: A0A0K2P0S8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1159554:AFK67 RS04070
gene id: 1159554:AFK67_RS04070
uniprot id: A0A0K2NYX5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1159554:AFK67 RS00260
gene id: 1159554:AFK67_RS00260
uniprot id: A0A0K2NXH5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

1159554:AFK67 RS11475
gene id: 1159554:AFK67_RS11475
uniprot id: A0A0K2P2T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1159554:AFK67 RS02610
gene id: 1159554:AFK67_RS02610
uniprot id: A0A0K2NY56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1159554:AFK67 RS02855
gene id: 1159554:AFK67_RS02855
uniprot id: A0A0K2NY95
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1159554:AFK67 RS03720
gene id: 1159554:AFK67_RS03720
uniprot id: A0A0K2NYK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

1159554:AFK67 RS06450
gene id: 1159554:AFK67_RS06450
uniprot id: A0A0K2P060
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1159554:AFK67 RS14935
gene id: 1159554:AFK67_RS14935
uniprot id: A0A0K2P4N2
names: Subunit
messages: Homodimer.

1159554:AFK67 RS13750
gene id: 1159554:AFK67_RS13750
uniprot id: A0A0K2P3W9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1159554:AFK67 RS02380
gene id: 1159554:AFK67_RS02380
uniprot id: A0A0K2NYK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SIS family. DiaA subfamily.
messages: Homotetramer; dimer of dimers.
messages: Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein.

1159554:AFK67 RS19235
gene id: 1159554:AFK67_RS19235
uniprot id: A0A0K2P7H5
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1159554:AFK67 RS05175
gene id: 1159554:AFK67_RS05175
uniprot id: A0A0K2NZJ0
names: Similarity
messages: Belongs to the P(II) protein family.

1159554:AFK67 RS07985
gene id: 1159554:AFK67_RS07985
uniprot id: A0A0K2P104
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1159554:AFK67 RS02235
gene id: 1159554:AFK67_RS02235
uniprot id: A0A0K2NYI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1159554:AFK67 RS08425
gene id: 1159554:AFK67_RS08425
uniprot id: A0A0K2P147
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in both the arginine and lysine biosynthetic pathways.

1159554:AFK67 RS02565
gene id: 1159554:AFK67_RS02565
uniprot id: A0A0K2NXY1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1159554:AFK67 RS13580
gene id: 1159554:AFK67_RS13580
uniprot id: A0A0K2P3T8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1159554:AFK67 RS16920
gene id: 1159554:AFK67_RS16920
uniprot id: A0A0K2P5N4
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1159554:AFK67 RS18830
gene id: 1159554:AFK67_RS18830
uniprot id: A0A0K2P6L9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1159554:AFK67 RS13115
gene id: 1159554:AFK67_RS13115
uniprot id: A0A0K2P3P0
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS03125
gene id: 1159554:AFK67_RS03125
uniprot id: A0A0K2NYE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

1159554:AFK67 RS06535
gene id: 1159554:AFK67_RS06535
uniprot id: A0A0K2P044
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1159554:AFK67 RS05825
gene id: 1159554:AFK67_RS05825
uniprot id: A0A0K2P0D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1159554:AFK67 RS18705
gene id: 1159554:AFK67_RS18705
uniprot id: A0A0K2P6J5
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1159554:AFK67 RS00035
gene id: 1159554:AFK67_RS00035
uniprot id: A0A0K2NWS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1159554:AFK67 RS04870
gene id: 1159554:AFK67_RS04870
uniprot id: A0A0K2NZC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SMC family. SbcC subfamily.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1159554:AFK67 RS20400
gene id: 1159554:AFK67_RS20400
uniprot id: A0A0K2P845
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

1159554:AFK67 RS17285
gene id: 1159554:AFK67_RS17285
uniprot id: A0A0K2P5W8
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS16940
gene id: 1159554:AFK67_RS16940
uniprot id: A0A0K2P682
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1159554:AFK67 RS20770
gene id: 1159554:AFK67_RS20770
uniprot id: A0A0K2P893
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS14635
gene id: 1159554:AFK67_RS14635
uniprot id: A0A0K2P4G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

1159554:AFK67 RS19805
gene id: 1159554:AFK67_RS19805
uniprot id: A0A0K2P7S4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS08140
gene id: 1159554:AFK67_RS08140
uniprot id: A0A0K2P0X6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

1159554:AFK67 RS03845
gene id: 1159554:AFK67_RS03845
uniprot id: A0A0K2NYU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS13590
gene id: 1159554:AFK67_RS13590
uniprot id: A0A0K2P3Z5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS14430
gene id: 1159554:AFK67_RS14430
uniprot id: A0A0K2P4D3
names: Similarity
messages: Belongs to the UPF0115 family.

1159554:AFK67 RS18060
gene id: 1159554:AFK67_RS18060
uniprot id: A0A0K2P691
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1159554:AFK67 RS01990
gene id: 1159554:AFK67_RS01990
uniprot id: A0A0K2NYE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.
messages: Homodimer.

1159554:AFK67 RS06865
gene id: 1159554:AFK67_RS06865
uniprot id: A0A0K2P7U4
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1159554:AFK67 RS16860
gene id: 1159554:AFK67_RS16860
uniprot id: A0A0K2P5N6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1159554:AFK67 RS10910
gene id: 1159554:AFK67_RS10910
uniprot id: A0A0K2P2F2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1159554:AFK67 RS20505
gene id: 1159554:AFK67_RS20505
uniprot id: A0A0K2P7K6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS19400
gene id: 1159554:AFK67_RS19400
uniprot id: A0A0K2P6X3
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS03360
gene id: 1159554:AFK67_RS03360
uniprot id: A0A0K2NYJ2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1159554:AFK67 RS00290
gene id: 1159554:AFK67_RS00290
uniprot id: A0A0K2NWZ8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1159554:AFK67 RS07700
gene id: 1159554:AFK67_RS07700
uniprot id: A0A0K2P0V9
names: Function
messages: May be involved in the biogenesis of curli organelles.

1159554:AFK67 RS17765
gene id: 1159554:AFK67_RS17765
uniprot id: A0A0K2P656
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS14215
gene id: 1159554:AFK67_RS14215
uniprot id: A0A0K2P456
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 5DNU family.
messages: Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.
messages: Cytoplasm
messages: Homodimer.

1159554:AFK67 RS05270
gene id: 1159554:AFK67_RS05270
uniprot id: A0A0K2NZG4
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS16895
gene id: 1159554:AFK67_RS16895
uniprot id: A0A0K2P5M9
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

1159554:AFK67 RS15265
gene id: 1159554:AFK67_RS15265
uniprot id: A0A0K2P4W1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

1159554:AFK67 RS05125
gene id: 1159554:AFK67_RS05125
uniprot id: A0A0K2NZH4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1159554:AFK67 RS09150
gene id: 1159554:AFK67_RS09150
uniprot id: A0A0K2P271
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS03660
gene id: 1159554:AFK67_RS03660
uniprot id: A0A0K2NZ77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1159554:AFK67 RS05880
gene id: 1159554:AFK67_RS05880
uniprot id: A0A0K2P0E8
names: Similarity
messages: Belongs to the universal stress protein A family.

1159554:AFK67 RS17055
gene id: 1159554:AFK67_RS17055
uniprot id: A0A0K2P5N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family.
messages: Cell outer membrane

1159554:AFK67 RS17570
gene id: 1159554:AFK67_RS17570
uniprot id: A0A0K2P5X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1159554:AFK67 RS14205
gene id: 1159554:AFK67_RS14205
uniprot id: A0A0K2P494
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1159554:AFK67 RS18420
gene id: 1159554:AFK67_RS18420
uniprot id: A0A0K2P738
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.

1159554:AFK67 RS07575
gene id: 1159554:AFK67_RS07575
uniprot id: A0A0K2P0P1
names: Function
names: Similarity
messages: Belongs to the RutC family.
messages: Involved in pyrimidine catabolism. Catalyzes the deamination of 3-aminoacrylate to malonic semialdehyde, a reaction that can also occur spontaneously. RutC may facilitate the reaction and modulate the metabolic fitness, rather than catalyzing essential functions.

1159554:AFK67 RS16720
gene id: 1159554:AFK67_RS16720
uniprot id: A0A0K2P5F7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: In the C-terminal section; belongs to the ATP-dependent AMP-binding enzyme family.
messages: In the N-terminal section; belongs to the 2-acyl-GPE acetyltransferase family.
messages: Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1.

1159554:AFK67 RS13035
gene id: 1159554:AFK67_RS13035
uniprot id: A0A0K2P3I9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA gyrase inhibitor family.
messages: Cytoplasm
messages: Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell.
messages: Interacts with DNA gyrase.

1159554:AFK67 RS03860
gene id: 1159554:AFK67_RS03860
uniprot id: A0A0K2NYM7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1159554:AFK67 RS18945
gene id: 1159554:AFK67_RS18945
uniprot id: A0A0K2P7C5
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

1159554:AFK67 RS10980
gene id: 1159554:AFK67_RS10980
uniprot id: A0A0K2P372
names: Function
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.
messages: Catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA.

1159554:AFK67 RS19770
gene id: 1159554:AFK67_RS19770
uniprot id: A0A0K2P794
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS11500
gene id: 1159554:AFK67_RS11500
uniprot id: A0A0K2P7Y1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 37 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Periplasm
messages: Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system.

1159554:AFK67 RS02580
gene id: 1159554:AFK67_RS02580
uniprot id: A0A0K2NYN9
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1159554:AFK67 RS04730
gene id: 1159554:AFK67_RS04730
uniprot id: A0A0K2NZB4
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Asr family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Periplasm
messages: Proteolytic processing gives rise to the active protein.
messages: Required for growth and/or survival at acidic conditions.

1159554:AFK67 RS00045
gene id: 1159554:AFK67_RS00045
uniprot id: A0A0K2NXD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1159554:AFK67 RS20805
gene id: 1159554:AFK67_RS20805
uniprot id: A0A0K2P892
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1159554:AFK67 RS19205
gene id: 1159554:AFK67_RS19205
uniprot id: A0A0K2P6W3
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1159554:AFK67 RS15380
gene id: 1159554:AFK67_RS15380
uniprot id: A0A0K2P4W5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E.
messages: Belongs to the RseA family.
messages: Cell inner membrane
messages: Interacts 1:1 with ECF RNA polymerase sigma-E (RpoE); this inhibits the interaction of sigma-E with the RNA polymerase catalytic core and leads to a decreased expression of sigma-E-regulated genes. Interacts with RseB.

1159554:AFK67 RS17490
gene id: 1159554:AFK67_RS17490
uniprot id: A0A0K2P5Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:citrate (SCF) symporter family.
messages: Cell membrane
messages: Uptake of citrate across the boundary membrane with the concomitant uptake of a sodium ion (symport system).

1159554:AFK67 RS00345
gene id: 1159554:AFK67_RS00345
uniprot id: A0A0K2NWT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent.
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Cytoplasm
messages: Monomer. Forms homomultimers of about 100-150 subunits at optimal growth temperatures. Conformation changes to monomers at high temperatures or high ionic concentrations.

1159554:AFK67 RS03935
gene id: 1159554:AFK67_RS03935
uniprot id: A0A0K2NYV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1159554:AFK67 RS21020
gene id: 1159554:AFK67_RS21020
uniprot id: A0A0K2P8D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPS (TC 1.B.20) family.
messages: Cell outer membrane
messages: Membrane

1159554:AFK67 RS12955
gene id: 1159554:AFK67_RS12955
uniprot id: A0A0K2P3N6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1159554:AFK67 RS01590
gene id: 1159554:AFK67_RS01590
uniprot id: A0A0K2NXJ4
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
messages: Belongs to the biotin--protein ligase family.

1159554:AFK67 RS07750
gene id: 1159554:AFK67_RS07750
uniprot id: A0A0K2P0W9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. OpgH subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
messages: Membrane

1159554:AFK67 RS06145
gene id: 1159554:AFK67_RS06145
uniprot id: A0A0K2P0I9
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1159554:AFK67 RS06810
gene id: 1159554:AFK67_RS06810
uniprot id: A0A0K2P0A1
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS16695
gene id: 1159554:AFK67_RS16695
uniprot id: A0A0K2P5F3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MutH family.
messages: Cytoplasm
messages: Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair.

1159554:AFK67 RS19200
gene id: 1159554:AFK67_RS19200
uniprot id: A0A0K2P7H0
names: Subcellular Location Annotation
messages: Cytoplasm

1159554:AFK67 RS08845
gene id: 1159554:AFK67_RS08845
uniprot id: A0A0K2P214
names: Similarity
messages: Belongs to the peptidase A31 family.

1159554:AFK67 RS16480
gene id: 1159554:AFK67_RS16480
uniprot id: A0A0K2P5E7
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS06400
gene id: 1159554:AFK67_RS06400
uniprot id: A0A0K2P055
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

1159554:AFK67 RS01365
gene id: 1159554:AFK67_RS01365
uniprot id: A0A0K2NXF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

1159554:AFK67 RS18680
gene id: 1159554:AFK67_RS18680
uniprot id: A0A0K2P7Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1159554:AFK67 RS19890
gene id: 1159554:AFK67_RS19890
uniprot id: A0A0K2P793
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1159554:AFK67 RS19715
gene id: 1159554:AFK67_RS19715
uniprot id: A0A0K2P735
names: Function
messages: Required for maximal bacterial cellulose synthesis.

1159554:AFK67 RS19230
gene id: 1159554:AFK67_RS19230
uniprot id: A0A0K2P801
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GlpE family.
messages: Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
messages: Cytoplasm

1159554:AFK67 RS12725
gene id: 1159554:AFK67_RS12725
uniprot id: A0A0K2P3E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

1159554:AFK67 RS10355
gene id: 1159554:AFK67_RS10355
uniprot id: A0A0K2P259
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1159554:AFK67 RS03895
gene id: 1159554:AFK67_RS03895
uniprot id: A0A0K2NYR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

1159554:AFK67 RS19165
gene id: 1159554:AFK67_RS19165
uniprot id: A0A0K2P6T2
names: Similarity
messages: Belongs to the FeoA family.

1159554:AFK67 RS20240
gene id: 1159554:AFK67_RS20240
uniprot id: A0A0K2P804
names: Similarity
messages: Belongs to the UPF0758 family. YicR subfamily.

1159554:AFK67 RS18820
gene id: 1159554:AFK67_RS18820
uniprot id: A0A0K2P6P3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1159554:AFK67 RS18025
gene id: 1159554:AFK67_RS18025
uniprot id: A0A0K2P6A5
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1159554:AFK67 RS08525
gene id: 1159554:AFK67_RS08525
uniprot id: A0A0K2P165
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1159554:AFK67 RS15900
gene id: 1159554:AFK67_RS15900
uniprot id: A0A0K2P516
names: Similarity
messages: Belongs to the peptidase C40 family.

1159554:AFK67 RS03170
gene id: 1159554:AFK67_RS03170
uniprot id: A0A0K2NYY9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1159554:AFK67 RS18915
gene id: 1159554:AFK67_RS18915
uniprot id: A0A0K2P6S8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefB subfamily.
messages: Cell inner membrane
messages: Interacts with the regulatory subunit KefG.
messages: Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.

1159554:AFK67 RS19670
gene id: 1159554:AFK67_RS19670
uniprot id: A0A0K2P773
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1159554:AFK67 RS01235
gene id: 1159554:AFK67_RS01235
uniprot id: A0A0K2NXF9
names: Similarity
messages: Belongs to the thioredoxin family.

1159554:AFK67 RS20870
gene id: 1159554:AFK67_RS20870
uniprot id: A0A0K2P8A1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1159554:AFK67 RS05935
gene id: 1159554:AFK67_RS05935
uniprot id: A0A0K2NZW9
names: Similarity
messages: Belongs to the RNase T2 family.

1159554:AFK67 RS10895
gene id: 1159554:AFK67_RS10895
uniprot id: A0A0K2P2K3
names: Similarity
messages: Belongs to the peptidase S49 family.

1159554:AFK67 RS19700
gene id: 1159554:AFK67_RS19700
uniprot id: A0A0K2P7Q0
names: Similarity
messages: Belongs to the peptidase M16 family.

1159554:AFK67 RS19625
gene id: 1159554:AFK67_RS19625
uniprot id: A0A0K2P742
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm
messages: Required for resistance to DNA-damaging agents.

1159554:AFK67 RS09105
gene id: 1159554:AFK67_RS09105
uniprot id: A0A0K2P1F1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1159554:AFK67 RS05525
gene id: 1159554:AFK67_RS05525
uniprot id: A0A0K2NZL4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1159554:AFK67 RS18775
gene id: 1159554:AFK67_RS18775
uniprot id: A0A0K2P6J6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1159554:AFK67 RS08430
gene id: 1159554:AFK67_RS08430
uniprot id: A0A0K2P193
names: Function
names: Similarity
messages: Belongs to the arginine N-succinyltransferase family.
messages: Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine.

1159554:AFK67 RS05310
gene id: 1159554:AFK67_RS05310
uniprot id: A0A0K2P061
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1159554:AFK67 RS07200
gene id: 1159554:AFK67_RS07200
uniprot id: A0A0K2P0I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS01355
gene id: 1159554:AFK67_RS01355
uniprot id: A0A0K2NXH9
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

1159554:AFK67 RS06565
gene id: 1159554:AFK67_RS06565
uniprot id: A0A0K2P090
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1159554:AFK67 RS18955
gene id: 1159554:AFK67_RS18955
uniprot id: A0A0K2P6N1
names: Similarity
messages: Belongs to the phosphoribulokinase family.

1159554:AFK67 RS13080
gene id: 1159554:AFK67_RS13080
uniprot id: A0A0K2P3Q6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Homodimer.

1159554:AFK67 RS06590
gene id: 1159554:AFK67_RS06590
uniprot id: A0A0K2P095
names: Similarity
messages: Belongs to the MoaD family.

1159554:AFK67 RS18030
gene id: 1159554:AFK67_RS18030
uniprot id: A0A0K2P676
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1159554:AFK67 RS01910
gene id: 1159554:AFK67_RS01910
uniprot id: A0A0K2NXV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1159554:AFK67 RS04620
gene id: 1159554:AFK67_RS04620
uniprot id: A0A0K2NZ46
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

1159554:AFK67 RS17325
gene id: 1159554:AFK67_RS17325
uniprot id: A0A0K2P5T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1159554:AFK67 RS18150
gene id: 1159554:AFK67_RS18150
uniprot id: A0A0K2P6C4
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

1159554:AFK67 RS02425
gene id: 1159554:AFK67_RS02425
uniprot id: A0A0K2NXV5
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS17680
gene id: 1159554:AFK67_RS17680
uniprot id: A0A0K2P615
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

1159554:AFK67 RS13705
gene id: 1159554:AFK67_RS13705
uniprot id: A0A0K2P400
names: Similarity
messages: Belongs to the UPF0352 family.

1159554:AFK67 RS01275
gene id: 1159554:AFK67_RS01275
uniprot id: A0A0K2NXI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WecD family.
messages: Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino-4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA).
messages: Homodimer.

1159554:AFK67 RS17950
gene id: 1159554:AFK67_RS17950
uniprot id: A0A0K2P693
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PriB family.
messages: Binds single-stranded DNA at the primosome assembly site (PAS).
messages: Component of the preprimosomal complex composed of PriA, PriB, PriC, DnaB and DnaT. Upon transient interaction with DnaG it forms the primosome.

1159554:AFK67 RS18795
gene id: 1159554:AFK67_RS18795
uniprot id: A0A0K2P6N9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1159554:AFK67 RS17040
gene id: 1159554:AFK67_RS17040
uniprot id: A0A0K2P6A2
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

1159554:AFK67 RS07105
gene id: 1159554:AFK67_RS07105
uniprot id: A0A0K2P0K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1159554:AFK67 RS16980
gene id: 1159554:AFK67_RS16980
uniprot id: A0A0K2P5L7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1159554:AFK67 RS14240
gene id: 1159554:AFK67_RS14240
uniprot id: A0A0K2P461
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1159554:AFK67 RS17010
gene id: 1159554:AFK67_RS17010
uniprot id: A0A0K2P5R6
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1159554:AFK67 RS20065
gene id: 1159554:AFK67_RS20065
uniprot id: A0A0K2P7F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cdh family.
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS18870
gene id: 1159554:AFK67_RS18870
uniprot id: A0A0K2P7B2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1159554:AFK67 RS04700
gene id: 1159554:AFK67_RS04700
uniprot id: A0A0K2NZA9
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS18105
gene id: 1159554:AFK67_RS18105
uniprot id: A0A0K2P695
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1159554:AFK67 RS19195
gene id: 1159554:AFK67_RS19195
uniprot id: A0A0K2P6Y2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

1159554:AFK67 RS05090
gene id: 1159554:AFK67_RS05090
uniprot id: A0A0K2NZH7
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1159554:AFK67 RS13175
gene id: 1159554:AFK67_RS13175
uniprot id: M9NH59
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1159554:AFK67 RS02630
gene id: 1159554:AFK67_RS02630
uniprot id: A0A0K2NYP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1159554:AFK67 RS14980
gene id: 1159554:AFK67_RS14980
uniprot id: A0A0K2P4J3
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS16970
gene id: 1159554:AFK67_RS16970
uniprot id: A0A0K2P5P3
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1159554:AFK67 RS18270
gene id: 1159554:AFK67_RS18270
uniprot id: A0A0K2P6C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hok/gef family.
messages: Cell inner membrane

1159554:AFK67 RS06150
gene id: 1159554:AFK67_RS06150
uniprot id: A0A0K2P004
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1159554:AFK67 RS02590
gene id: 1159554:AFK67_RS02590
uniprot id: A0A0K2NXY6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Heterododecamer (2C3:3R2) of six catalytic PyrB chains organized as two trimers (C3), and six regulatory PyrI chains organized as three dimers (R2).
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

1159554:AFK67 RS07655
gene id: 1159554:AFK67_RS07655
uniprot id: A0A0K2P0N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

1159554:AFK67 RS21300
gene id: 1159554:AFK67_RS21300
uniprot id: A0A0K2P8J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family.
messages: Membrane

1159554:AFK67 RS06790
gene id: 1159554:AFK67_RS06790
uniprot id: A0A0K2P0D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane
messages: Membrane

1159554:AFK67 RS04590
gene id: 1159554:AFK67_RS04590
uniprot id: A0A0K2NZ22
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1159554:AFK67 RS03225
gene id: 1159554:AFK67_RS03225
uniprot id: A0A0K2NYH5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1159554:AFK67 RS19865
gene id: 1159554:AFK67_RS19865
uniprot id: A0A0K2P788
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS10925
gene id: 1159554:AFK67_RS10925
uniprot id: A0A0K2P8G8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the anthranilate synthase component I family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1159554:AFK67 RS16405
gene id: 1159554:AFK67_RS16405
uniprot id: A0A0K2P5D3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Homodimer.

1159554:AFK67 RS12945
gene id: 1159554:AFK67_RS12945
uniprot id: A0A0K2P3H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Metabolite:H+ Symporter (MHS) family (TC 2.A.1.6) family.
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS15440
gene id: 1159554:AFK67_RS15440
uniprot id: A0A0K2P4T6
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-II family.

1159554:AFK67 RS08785
gene id: 1159554:AFK67_RS08785
uniprot id: A0A0K2P1B7
names: Similarity
messages: Belongs to the HypD family.

1159554:AFK67 RS06960
gene id: 1159554:AFK67_RS06960
uniprot id: A0A0K2P117
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

1159554:AFK67 RS02500
gene id: 1159554:AFK67_RS02500
uniprot id: A0A0K2NYM5
names: Similarity
messages: Belongs to the UxaA family.

1159554:AFK67 RS01865
gene id: 1159554:AFK67_RS01865
uniprot id: A0A0K2NYC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1159554:AFK67 RS06325
gene id: 1159554:AFK67_RS06325
uniprot id: A0A0K2P040
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth.

1159554:AFK67 RS16420
gene id: 1159554:AFK67_RS16420
uniprot id: A0A0K2P5F2
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

1159554:AFK67 RS20430
gene id: 1159554:AFK67_RS20430
uniprot id: A0A0K2P810
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

1159554:AFK67 RS13475
gene id: 1159554:AFK67_RS13475
uniprot id: A0A0K2P3X8
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS05180
gene id: 1159554:AFK67_RS05180
uniprot id: A0A0K2P038
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS03600
gene id: 1159554:AFK67_RS03600
uniprot id: A0A0K2NYK5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1159554:AFK67 RS01625
gene id: 1159554:AFK67_RS01625
uniprot id: A0A0K2NXL9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1159554:AFK67 RS13575
gene id: 1159554:AFK67_RS13575
uniprot id: A0A0K2P3X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1159554:AFK67 RS16670
gene id: 1159554:AFK67_RS16670
uniprot id: A0A0K2P5F0
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS11285
gene id: 1159554:AFK67_RS11285
uniprot id: A0A0K2P3B4
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1159554:AFK67 RS02115
gene id: 1159554:AFK67_RS02115
uniprot id: A0A0K2NXW7
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

1159554:AFK67 RS12495
gene id: 1159554:AFK67_RS12495
uniprot id: A0A0K2P3E0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm
messages: Required for resistance to DNA-damaging agents.

1159554:AFK67 RS06330
gene id: 1159554:AFK67_RS06330
uniprot id: A0A0K2NZY1
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

1159554:AFK67 RS05510
gene id: 1159554:AFK67_RS05510
uniprot id: A0A0K2P094
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1159554:AFK67 RS11085
gene id: 1159554:AFK67_RS11085
uniprot id: A0A0K2P388
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1159554:AFK67 RS07855
gene id: 1159554:AFK67_RS07855
uniprot id: A0A0K2P1J4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

1159554:AFK67 RS16260
gene id: 1159554:AFK67_RS16260
uniprot id: A0A0K2P5A9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1159554:AFK67 RS03130
gene id: 1159554:AFK67_RS03130
uniprot id: A0A0K2NY79
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LplA family.
messages: Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.
messages: Cytoplasm
messages: In the transfer reaction, the free carboxyl group of lipoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.
messages: Monomer.

1159554:AFK67 RS16750
gene id: 1159554:AFK67_RS16750
uniprot id: A0A0K2P5G8
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1159554:AFK67 RS01265
gene id: 1159554:AFK67_RS01265
uniprot id: A0A0K2NXA3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1159554:AFK67 RS18090
gene id: 1159554:AFK67_RS18090
uniprot id: A0A0K2P6Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1159554:AFK67 RS18745
gene id: 1159554:AFK67_RS18745
uniprot id: A0A0K2P6M7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1159554:AFK67 RS18500
gene id: 1159554:AFK67_RS18500
uniprot id: A0A0K2P752
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1159554:AFK67 RS18950
gene id: 1159554:AFK67_RS18950
uniprot id: A0A0K2P6R5
names: Similarity
messages: Belongs to the UPF0270 family.

1159554:AFK67 RS17260
gene id: 1159554:AFK67_RS17260
uniprot id: A0A0K2P5W3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

1159554:AFK67 RS03485
gene id: 1159554:AFK67_RS03485
uniprot id: A0A0K2NYL8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

1159554:AFK67 RS00765
gene id: 1159554:AFK67_RS00765
uniprot id: A0A0K2NXP5
names: Similarity
messages: Belongs to the FBPase class 2 family.

1159554:AFK67 RS04990
gene id: 1159554:AFK67_RS04990
uniprot id: A0A0K2NZF8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1159554:AFK67 RS08215
gene id: 1159554:AFK67_RS08215
uniprot id: A0A0K2P148
names: Similarity
messages: Belongs to the ArsC family.

1159554:AFK67 RS10640
gene id: 1159554:AFK67_RS10640
uniprot id: A0A0K2P313
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0283 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS15375
gene id: 1159554:AFK67_RS15375
uniprot id: A0A0K2P5I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

1159554:AFK67 RS00025
gene id: 1159554:AFK67_RS00025
uniprot id: A0A0K2NWU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1159554:AFK67 RS20175
gene id: 1159554:AFK67_RS20175
uniprot id: A0A0K2P7E8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

1159554:AFK67 RS14170
gene id: 1159554:AFK67_RS14170
uniprot id: A0A0K2P488
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1159554:AFK67 RS19260
gene id: 1159554:AFK67_RS19260
uniprot id: A0A0K2P7I0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Allosterically activated by fructose-1,6-bisphosphate (F16BP) and inhibited by AMP.
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1159554:AFK67 RS14890
gene id: 1159554:AFK67_RS14890
uniprot id: A0A0K2P573
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. EntS (TC 2.A.1.38) family.
messages: Cell inner membrane
messages: Component of an export pathway for enterobactin.
messages: Membrane

1159554:AFK67 RS14785
gene id: 1159554:AFK67_RS14785
uniprot id: A0A0K2P550
names: Similarity
messages: Belongs to the acetyltransferase family. YpeA subfamily.

1159554:AFK67 RS20780
gene id: 1159554:AFK67_RS20780
uniprot id: A0A0K2P888
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS05865
gene id: 1159554:AFK67_RS05865
uniprot id: A0A0K2NZP4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1159554:AFK67 RS09495
gene id: 1159554:AFK67_RS09495
uniprot id: A0A0K2P1T0
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: 4-aminobutanal can spontaneously cyclize to 1-pyrroline, and 5-aminopentanal to 1-piperideine.
messages: Belongs to the aldehyde dehydrogenase family. Gamma-aminobutyraldehyde dehydrogenase subfamily.
messages: Catalyzes the oxidation 4-aminobutanal (gamma-aminobutyraldehyde) to 4-aminobutanoate (gamma-aminobutyrate or GABA). This is the second step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate via 4-aminobutanal. Also functions as a 5-aminopentanal dehydrogenase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
messages: Homotetramer.

1159554:AFK67 RS07080
gene id: 1159554:AFK67_RS07080
uniprot id: A0A0K2P0I5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

1159554:AFK67 RS11025
gene id: 1159554:AFK67_RS11025
uniprot id: A0A0K2P2I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS06760
gene id: 1159554:AFK67_RS06760
uniprot id: A0A0K2P091
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpX family.
messages: Cell outer membrane

1159554:AFK67 RS08630
gene id: 1159554:AFK67_RS08630
uniprot id: A0A0K2P185
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

1159554:AFK67 RS06015
gene id: 1159554:AFK67_RS06015
uniprot id: A0A0K2NZS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1159554:AFK67 RS03520
gene id: 1159554:AFK67_RS03520
uniprot id: A0A0K2NYF5
names: Similarity
messages: Belongs to the ribulokinase family.

1159554:AFK67 RS18600
gene id: 1159554:AFK67_RS18600
uniprot id: A0A0K2P6M3
names: Similarity
messages: Belongs to the malate synthase family.

1159554:AFK67 RS02320
gene id: 1159554:AFK67_RS02320
uniprot id: A0A0K2NXX3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease subfamily.
messages: Cell inner membrane
messages: Involved in transporting aromatic amino acids across the cytoplasmic membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1159554:AFK67 RS18035
gene id: 1159554:AFK67_RS18035
uniprot id: A0A0K2P688
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1159554:AFK67 RS08305
gene id: 1159554:AFK67_RS08305
uniprot id: A0A0K2P128
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0756 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1159554:AFK67 RS11725
gene id: 1159554:AFK67_RS11725
uniprot id: A0A0K2P2V2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport.

1159554:AFK67 RS12420
gene id: 1159554:AFK67_RS12420
uniprot id: A0A0K2P378
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1159554:AFK67 RS07305
gene id: 1159554:AFK67_RS07305
uniprot id: A0A0K2P0J7
names: Similarity
messages: Belongs to the YkuD family.

1159554:AFK67 RS19815
gene id: 1159554:AFK67_RS19815
uniprot id: A0A0K2P744
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS18560
gene id: 1159554:AFK67_RS18560
uniprot id: A0A0K2P6J9
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1159554:AFK67 RS07180
gene id: 1159554:AFK67_RS07180
uniprot id: A0A0K2P0L6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase 1 under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

1159554:AFK67 RS01285
gene id: 1159554:AFK67_RS01285
uniprot id: A0A0K2NXG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family.
messages: Cell inner membrane
messages: Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA).
messages: Membrane
messages: Probably part of a complex composed of WzxE, WzyE and WzzE.

1159554:AFK67 RS19350
gene id: 1159554:AFK67_RS19350
uniprot id: A0A0K2P6W0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

1159554:AFK67 RS06950
gene id: 1159554:AFK67_RS06950
uniprot id: A0A0K2P0D0
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

1159554:AFK67 RS05395
gene id: 1159554:AFK67_RS05395
uniprot id: A0A0K2NZG2
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1159554:AFK67 RS15010
gene id: 1159554:AFK67_RS15010
uniprot id: A0A0K2P4P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1159554:AFK67 RS05845
gene id: 1159554:AFK67_RS05845
uniprot id: A0A0K2NZR5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Monomer.

1159554:AFK67 RS07905
gene id: 1159554:AFK67_RS07905
uniprot id: A0A0K2P1K4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1159554:AFK67 RS01295
gene id: 1159554:AFK67_RS01295
uniprot id: A0A0K2NXE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WzyE family.
messages: Cell inner membrane
messages: Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units.
messages: Probably part of a complex composed of WzxE, WzyE and WzzE.

1159554:AFK67 RS19475
gene id: 1159554:AFK67_RS19475
uniprot id: A0A0K2P712
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cytoplasm
messages: Interacts with IscS.
messages: Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.

1159554:AFK67 RS12410
gene id: 1159554:AFK67_RS12410
uniprot id: A0A0K2P3Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

1159554:AFK67 RS16770
gene id: 1159554:AFK67_RS16770
uniprot id: A0A0K2P5G7
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1159554:AFK67 RS07545
gene id: 1159554:AFK67_RS07545
uniprot id: A0A0K2P0L4
names: Cofactor
names: Similarity
messages: Belongs to the WrbA family.
messages: Binds 1 FMN per monomer.

1159554:AFK67 RS05460
gene id: 1159554:AFK67_RS05460
uniprot id: A0A0K2P085
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1159554:AFK67 RS20530
gene id: 1159554:AFK67_RS20530
uniprot id: A0A0K2P7L0
names: Similarity
names: Subunit
messages: Belongs to the ViaA family.
messages: Possible formation of a ternary complex RavA-ViaA-CadA.

1159554:AFK67 RS18175
gene id: 1159554:AFK67_RS18175
uniprot id: A0A0K2P6C8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1159554:AFK67 RS15360
gene id: 1159554:AFK67_RS15360
uniprot id: A0A0K2P4S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1159554:AFK67 RS01955
gene id: 1159554:AFK67_RS01955
uniprot id: A0A0K2NXR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell membrane
messages: Forms an efflux pump with AaeB.

1159554:AFK67 RS05325
gene id: 1159554:AFK67_RS05325
uniprot id: A0A0K2NZH5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1159554:AFK67 RS00090
gene id: 1159554:AFK67_RS00090
uniprot id: A0A0K2NWY5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1159554:AFK67 RS12425
gene id: 1159554:AFK67_RS12425
uniprot id: A0A0K2P389
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

1159554:AFK67 RS09475
gene id: 1159554:AFK67_RS09475
uniprot id: A0A0K2P1M6
names: Similarity
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.

1159554:AFK67 RS13315
gene id: 1159554:AFK67_RS13315
uniprot id: A0A0K2P3Q2
names: Similarity
messages: Belongs to the alkylbase DNA glycosidase AlkA family.

1159554:AFK67 RS05025
gene id: 1159554:AFK67_RS05025
uniprot id: A0A0K2NZF5
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS08385
gene id: 1159554:AFK67_RS08385
uniprot id: A0A0K2P172
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

1159554:AFK67 RS00760
gene id: 1159554:AFK67_RS00760
uniprot id: A0A0K2NX99
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1159554:AFK67 RS01195
gene id: 1159554:AFK67_RS01195
uniprot id: A0A0K2NXC7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1159554:AFK67 RS07820
gene id: 1159554:AFK67_RS07820
uniprot id: A0A0K2P0T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. DHA1 family. MdtH (TC 2.A.1.2.21) subfamily.
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS14010
gene id: 1159554:AFK67_RS14010
uniprot id: A0A0K2P4Q9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the RcsB family.
messages: Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions.
messages: Interacts with RcsD.
messages: Phosphorylated and activated by RcsD.

1159554:AFK67 RS07065
gene id: 1159554:AFK67_RS07065
uniprot id: A0A0K2P0I0
names: Activity Regulation
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A peripheral cell membrane enzyme that catalyzes the oxidative decarboxylation of pyruvate to form acetate and CO(2). It channels electrons from the cytoplasm to the respiratory chain at the cell membrane via ubiquinone.
messages: Belongs to the TPP enzyme family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Cell membrane
messages: Has 4 domains; the Pyr domain which binds the pyrimidine moiety of the thiamine pyrophosphate cofactor, the FAD-binding domain, the PP-binding domain which binds the pyrophosphate portion of thiamine pyrophosphate and the C-terminal membrane binding region. The C-terminus is held closely against the rest of the protein and covers the active site; during activation it unfolds from the rest of the protein and forms an amphipathic helix upon membrane binding, exposing the active site.
messages: Homotetramer.
messages: The C-terminus inhibits activity; it has to move for the enzyme to be active. Activated by lipid-binding, which occurs via the C-terminus.

1159554:AFK67 RS18750
gene id: 1159554:AFK67_RS18750
uniprot id: A0A0K2P6J1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1159554:AFK67 RS00365
gene id: 1159554:AFK67_RS00365
uniprot id: A0A0K2NX13
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

1159554:AFK67 RS03440
gene id: 1159554:AFK67_RS03440
uniprot id: A0A0K2NYE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAD(P)H dehydrogenase (quinone) family. KefF subfamily.
messages: Cell inner membrane
messages: Homodimer. Interacts with KefC.
messages: Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefC. Shows redox enzymatic activity, but this enzymatic activity is not required for activation of KefC.

1159554:AFK67 RS08070
gene id: 1159554:AFK67_RS08070
uniprot id: A0A0K2P0Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1159554:AFK67 RS13680
gene id: 1159554:AFK67_RS13680
uniprot id: A0A0K2P3V8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1159554:AFK67 RS08800
gene id: 1159554:AFK67_RS08800
uniprot id: A0A0K2P1F3
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

1159554:AFK67 RS18470
gene id: 1159554:AFK67_RS18470
uniprot id: A0A0K2P747
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Monomer.
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

1159554:AFK67 RS01300
gene id: 1159554:AFK67_RS01300
uniprot id: A0A0K2NXI9
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family.
messages: Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis.

1159554:AFK67 RS16160
gene id: 1159554:AFK67_RS16160
uniprot id: A0A0K2P594
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

1159554:AFK67 RS01045
gene id: 1159554:AFK67_RS01045
uniprot id: A0A0K2NXU6
names: Similarity
messages: Belongs to the MQO family.

1159554:AFK67 RS10150
gene id: 1159554:AFK67_RS10150
uniprot id: A0A0K2P272
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1159554:AFK67 RS14615
gene id: 1159554:AFK67_RS14615
uniprot id: A0A0K2P4C3
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

1159554:AFK67 RS13905
gene id: 1159554:AFK67_RS13905
uniprot id: A0A0K2P433
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1159554:AFK67 RS14800
gene id: 1159554:AFK67_RS14800
uniprot id: A0A0K2P4F8
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1159554:AFK67 RS13335
gene id: 1159554:AFK67_RS13335
uniprot id: A0A0K2P3P4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Part of a tripartite efflux system composed of MdtA, MdtB and MdtC.

1159554:AFK67 RS15115
gene id: 1159554:AFK67_RS15115
uniprot id: A0A0K2P5C4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1159554:AFK67 RS12500
gene id: 1159554:AFK67_RS12500
uniprot id: A0A0K2P3A7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase 20 family.
messages: Homotetramer.
messages: Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor.

1159554:AFK67 RS01255
gene id: 1159554:AFK67_RS01255
uniprot id: A0A0K2NXY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
messages: Catalyzes the reversible epimerization at C-2 of UDP-N-acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues.
messages: Cytoplasm
messages: Homodimer.

1159554:AFK67 RS07230
gene id: 1159554:AFK67_RS07230
uniprot id: A0A0K2P0M6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1159554:AFK67 RS10855
gene id: 1159554:AFK67_RS10855
uniprot id: A0A0K2P2I3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapA family.
messages: Cell inner membrane
messages: Involved in the assembly of lipopolysaccharide (LPS).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1159554:AFK67 RS19360
gene id: 1159554:AFK67_RS19360
uniprot id: A0A0K2P7J7
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1159554:AFK67 RS09470
gene id: 1159554:AFK67_RS09470
uniprot id: A0A0K2P1S5
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1159554:AFK67 RS16565
gene id: 1159554:AFK67_RS16565
uniprot id: A0A0K2P5D6
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1159554:AFK67 RS14265
gene id: 1159554:AFK67_RS14265
uniprot id: A0A0K2P466
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1159554:AFK67 RS16465
gene id: 1159554:AFK67_RS16465
uniprot id: A0A0K2P5B5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1159554:AFK67 RS04220
gene id: 1159554:AFK67_RS04220
uniprot id: A0A0K2NZ00
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

1159554:AFK67 RS04050
gene id: 1159554:AFK67_RS04050
uniprot id: A0A0K2NYR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-(hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1159554:AFK67 RS14345
gene id: 1159554:AFK67_RS14345
uniprot id: A0A0K2P7W6
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

1159554:AFK67 RS03890
gene id: 1159554:AFK67_RS03890
uniprot id: A0A0K2P7M7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

1159554:AFK67 RS01655
gene id: 1159554:AFK67_RS01655
uniprot id: A0A0K2NXH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1159554:AFK67 RS17015
gene id: 1159554:AFK67_RS17015
uniprot id: A0A0K2P697
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
messages: Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
messages: Cytoplasm
messages: Homotetramer.

1159554:AFK67 RS06205
gene id: 1159554:AFK67_RS06205
uniprot id: A0A0K2NZV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SeqA family.
messages: Cytoplasm
messages: Homodimer. Polymerizes to form helical filaments.
messages: Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.

1159554:AFK67 RS14510
gene id: 1159554:AFK67_RS14510
uniprot id: A0A0K2P4E9
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS10045
gene id: 1159554:AFK67_RS10045
uniprot id: A0A0K2P2R1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family.
messages: Cell membrane
messages: Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites.
messages: Membrane

1159554:AFK67 RS14315
gene id: 1159554:AFK67_RS14315
uniprot id: A0A0K2P476
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

1159554:AFK67 RS18860
gene id: 1159554:AFK67_RS18860
uniprot id: A0A0K2P6M4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1159554:AFK67 RS18770
gene id: 1159554:AFK67_RS18770
uniprot id: A0A0K2P6N3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1159554:AFK67 RS15040
gene id: 1159554:AFK67_RS15040
uniprot id: A0A0K2P5A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1159554:AFK67 RS03635
gene id: 1159554:AFK67_RS03635
uniprot id: A0A0K2NZ70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1159554:AFK67 RS14195
gene id: 1159554:AFK67_RS14195
uniprot id: A0A0K2P4A0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1159554:AFK67 RS02890
gene id: 1159554:AFK67_RS02890
uniprot id: A0A0K2NY72
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

1159554:AFK67 RS10710
gene id: 1159554:AFK67_RS10710
uniprot id: A0A0K2P2C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1159554:AFK67 RS02860
gene id: 1159554:AFK67_RS02860
uniprot id: A0A0K2NY34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SymE family.
messages: Cytoplasm
messages: Involved in the degradation and recycling of damaged RNA. It is itself a target for degradation by the ATP-dependent protease Lon.

1159554:AFK67 RS14560
gene id: 1159554:AFK67_RS14560
uniprot id: A0A0K2P4F4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1159554:AFK67 RS08360
gene id: 1159554:AFK67_RS08360
uniprot id: A0A0K2P116
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

1159554:AFK67 RS18195
gene id: 1159554:AFK67_RS18195
uniprot id: A0A0K2P700
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CutA family.
messages: Binds 1 copper ion per subunit.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in resistance toward heavy metals.

1159554:AFK67 RS13275
gene id: 1159554:AFK67_RS13275
uniprot id: A0A0K2P3P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS13600
gene id: 1159554:AFK67_RS13600
uniprot id: A0A0K2P3Y1
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FruAB PTS system is involved in fructose transport.

1159554:AFK67 RS01640
gene id: 1159554:AFK67_RS01640
uniprot id: A0A0K2NXP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1159554:AFK67 RS06440
gene id: 1159554:AFK67_RS06440
uniprot id: A0A0K2P064
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS01080
gene id: 1159554:AFK67_RS01080
uniprot id: A0A0K2NX73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1159554:AFK67 RS08795
gene id: 1159554:AFK67_RS08795
uniprot id: A0A0K2P203
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

1159554:AFK67 RS09670
gene id: 1159554:AFK67_RS09670
uniprot id: A0A0K2P1T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1159554:AFK67 RS03030
gene id: 1159554:AFK67_RS03030
uniprot id: A0A0K2NYW8
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.

1159554:AFK67 RS19480
gene id: 1159554:AFK67_RS19480
uniprot id: A0A0K2P6X6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1159554:AFK67 RS10930
gene id: 1159554:AFK67_RS10930
uniprot id: A0A0K2P364
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1159554:AFK67 RS16745
gene id: 1159554:AFK67_RS16745
uniprot id: A0A0K2P5G2
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1159554:AFK67 RS04115
gene id: 1159554:AFK67_RS04115
uniprot id: A0A0K2NZH9
names: Similarity
messages: Belongs to the UPF0253 family.

1159554:AFK67 RS00320
gene id: 1159554:AFK67_RS00320
uniprot id: A0A0K2NWS6
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS16275
gene id: 1159554:AFK67_RS16275
uniprot id: A0A0K2P582
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1159554:AFK67 RS00890
gene id: 1159554:AFK67_RS00890
uniprot id: A0A0K2NX36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the rhamnose mutarotase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the anomeric conversion of L-rhamnose.

1159554:AFK67 RS01850
gene id: 1159554:AFK67_RS01850
uniprot id: A0A0K2P7L3
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1159554:AFK67 RS03320
gene id: 1159554:AFK67_RS03320
uniprot id: A0A0K2NYE9
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1159554:AFK67 RS16450
gene id: 1159554:AFK67_RS16450
uniprot id: A0A0K2P607
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

1159554:AFK67 RS08130
gene id: 1159554:AFK67_RS08130
uniprot id: A0A0K2P1P6
names: Subcellular Location Annotation
messages: Cell inner membrane

1159554:AFK67 RS13410
gene id: 1159554:AFK67_RS13410
uniprot id: A0A0K2P3U6
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS13605
gene id: 1159554:AFK67_RS13605
uniprot id: A0A0K2P3U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Set transporter family.
messages: Membrane

1159554:AFK67 RS06175
gene id: 1159554:AFK67_RS06175
uniprot id: A0A0K2P009
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

1159554:AFK67 RS04980
gene id: 1159554:AFK67_RS04980
uniprot id: A0A0K2NZ82
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

1159554:AFK67 RS02600
gene id: 1159554:AFK67_RS02600
uniprot id: A0A0K2NY69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1159554:AFK67 RS11245
gene id: 1159554:AFK67_RS11245
uniprot id: A0A0K2P7Y3
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1159554:AFK67 RS19675
gene id: 1159554:AFK67_RS19675
uniprot id: A0A0K2P7P5
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS09760
gene id: 1159554:AFK67_RS09760
uniprot id: A0A0K2P1Z3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1159554:AFK67 RS14310
gene id: 1159554:AFK67_RS14310
uniprot id: A0A0K2P472
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

1159554:AFK67 RS01425
gene id: 1159554:AFK67_RS01425
uniprot id: A0A0K2NY24
names: Similarity
messages: Belongs to the Rht family.

1159554:AFK67 RS13505
gene id: 1159554:AFK67_RS13505
uniprot id: A0A0K2P3Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0299 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS04025
gene id: 1159554:AFK67_RS04025
uniprot id: A0A0K2NYQ9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.

1159554:AFK67 RS08685
gene id: 1159554:AFK67_RS08685
uniprot id: A0A0K2P197
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thioesterase PaaI family.
messages: Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA).
messages: Homotetramer. Dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1159554:AFK67 RS05940
gene id: 1159554:AFK67_RS05940
uniprot id: A0A0K2NZQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.
messages: Membrane

1159554:AFK67 RS01385
gene id: 1159554:AFK67_RS01385
uniprot id: A0A0K2NXC4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1159554:AFK67 RS06390
gene id: 1159554:AFK67_RS06390
uniprot id: A0A0K2P059
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1159554:AFK67 RS07925
gene id: 1159554:AFK67_RS07925
uniprot id: A0A0K2P103
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Belongs to the RNase E/G family. RNase G subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

1159554:AFK67 RS17925
gene id: 1159554:AFK67_RS17925
uniprot id: A0A0K2P689
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS04150
gene id: 1159554:AFK67_RS04150
uniprot id: A0A0K2NYU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1159554:AFK67 RS01025
gene id: 1159554:AFK67_RS01025
uniprot id: A0A0K2NXC5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1159554:AFK67 RS19380
gene id: 1159554:AFK67_RS19380
uniprot id: A0A0K2P716
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS19550
gene id: 1159554:AFK67_RS19550
uniprot id: A0A0K2P727
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1159554:AFK67 RS18200
gene id: 1159554:AFK67_RS18200
uniprot id: A0A0K2P6D3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

1159554:AFK67 RS01650
gene id: 1159554:AFK67_RS01650
uniprot id: A0A0K2NXM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1159554:AFK67 RS05365
gene id: 1159554:AFK67_RS05365
uniprot id: A0A0K2NZL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1159554:AFK67 RS04155
gene id: 1159554:AFK67_RS04155
uniprot id: A0A0K2NYW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1159554:AFK67 RS05230
gene id: 1159554:AFK67_RS05230
uniprot id: A0A0K2P046
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

1159554:AFK67 RS07850
gene id: 1159554:AFK67_RS07850
uniprot id: A0A0K2P0Y8
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

1159554:AFK67 RS14075
gene id: 1159554:AFK67_RS14075
uniprot id: A0A0K2P812
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

1159554:AFK67 RS06090
gene id: 1159554:AFK67_RS06090
uniprot id: A0A0K2P7P2
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1159554:AFK67 RS02305
gene id: 1159554:AFK67_RS02305
uniprot id: A0A0K2NYJ3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Homodimer.
messages: May be involved in cell division.

1159554:AFK67 RS06000
gene id: 1159554:AFK67_RS06000
uniprot id: A0A0K2NZY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1159554:AFK67 RS09680
gene id: 1159554:AFK67_RS09680
uniprot id: A0A0K2P2H8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1159554:AFK67 RS14665
gene id: 1159554:AFK67_RS14665
uniprot id: A0A0K2P528
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

1159554:AFK67 RS19935
gene id: 1159554:AFK67_RS19935
uniprot id: A0A0K2P7V3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS08335
gene id: 1159554:AFK67_RS08335
uniprot id: A0A0K2P112
names: Similarity
messages: Belongs to the UPF0229 family.

1159554:AFK67 RS07215
gene id: 1159554:AFK67_RS07215
uniprot id: A0A0K2P0M0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1159554:AFK67 RS06610
gene id: 1159554:AFK67_RS06610
uniprot id: A0A0K2P058
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsB sub-subfamily.
messages: Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane

1159554:AFK67 RS01055
gene id: 1159554:AFK67_RS01055
uniprot id: A0A0K2NX68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

1159554:AFK67 RS04395
gene id: 1159554:AFK67_RS04395
uniprot id: A0A0K2NZ35
names: Function
names: Similarity
messages: Belongs to the PqqB family.
messages: May be involved in the transport of PQQ or its precursor to the periplasm.

1159554:AFK67 RS12950
gene id: 1159554:AFK67_RS12950
uniprot id: A0A0K2P3I7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1159554:AFK67 RS02060
gene id: 1159554:AFK67_RS02060
uniprot id: A0A0K2NXV7
names: PTM
names: Subcellular Location Annotation
messages: Activation requires a sequential transfer of a phosphate group from a His in the primary transmitter domain, to an Asp in the receiver domain and to a His in the secondary transmitter domain.
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS03115
gene id: 1159554:AFK67_RS03115
uniprot id: A0A0K2NYF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.
messages: The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.

1159554:AFK67 RS11035
gene id: 1159554:AFK67_RS11035
uniprot id: A0A0K2P380
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

1159554:AFK67 RS07390
gene id: 1159554:AFK67_RS07390
uniprot id: A0A0K2P0Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

1159554:AFK67 RS07070
gene id: 1159554:AFK67_RS07070
uniprot id: A0A0K2P0C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1159554:AFK67 RS18895
gene id: 1159554:AFK67_RS18895
uniprot id: A0A0K2P7B6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1159554:AFK67 RS06785
gene id: 1159554:AFK67_RS06785
uniprot id: A0A0K2P096
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS11265
gene id: 1159554:AFK67_RS11265
uniprot id: A0A0K2P2Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1159554:AFK67 RS14750
gene id: 1159554:AFK67_RS14750
uniprot id: A0A0K2P4E7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1159554:AFK67 RS17130
gene id: 1159554:AFK67_RS17130
uniprot id: A0A0K2P5P7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsP family.
messages: Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress.
messages: Periplasm

1159554:AFK67 RS03005
gene id: 1159554:AFK67_RS03005
uniprot id: A0A0K2NYW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Cell inner membrane
messages: Involved in succinate export with YjjP. Both proteins are required for export.
messages: Membrane
messages: The transporter is composed of YjjB and YjjP.

1159554:AFK67 RS15300
gene id: 1159554:AFK67_RS15300
uniprot id: A0A0K2P5H3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: In the C-terminal section; belongs to the transglycosylase Slt family.
messages: In the N-terminal section; belongs to the bacterial solute-binding protein 3 family.
messages: Membrane
messages: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
messages: The N-terminal domain does not have lytic activity and probably modulates enzymatic activity. The C-terminal domain is the catalytic active domain.

1159554:AFK67 RS11030
gene id: 1159554:AFK67_RS11030
uniprot id: A0A0K2P2M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS08790
gene id: 1159554:AFK67_RS08790
uniprot id: A0A0K2P1G5
names: Similarity
messages: Belongs to the HupF/HypC family.

1159554:AFK67 RS09185
gene id: 1159554:AFK67_RS09185
uniprot id: A0A0K2P1G6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SlyA family.
messages: Homodimer.
messages: Transcription regulator that can specifically activate or repress expression of target genes.

1159554:AFK67 RS19560
gene id: 1159554:AFK67_RS19560
uniprot id: A0A0K2P703
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS11805
gene id: 1159554:AFK67_RS11805
uniprot id: A0A0K2P317
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PqiA family.
messages: Component of a transport pathway that contributes to membrane integrity.
messages: Membrane

1159554:AFK67 RS09165
gene id: 1159554:AFK67_RS09165
uniprot id: A0A0K2P1I4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1159554:AFK67 RS01755
gene id: 1159554:AFK67_RS01755
uniprot id: A0A0K2NXR0
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1159554:AFK67 RS20415
gene id: 1159554:AFK67_RS20415
uniprot id: A0A0K2P853
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1159554:AFK67 RS18930
gene id: 1159554:AFK67_RS18930
uniprot id: A0A0K2P6M6
names: Similarity
messages: Belongs to the NAPRTase family.

1159554:AFK67 RS12320
gene id: 1159554:AFK67_RS12320
uniprot id: A0A0K2P356
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

1159554:AFK67 RS05620
gene id: 1159554:AFK67_RS05620
uniprot id: A0A0K2NZR8
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS10680
gene id: 1159554:AFK67_RS10680
uniprot id: A0A0K2P296
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

1159554:AFK67 RS14990
gene id: 1159554:AFK67_RS14990
uniprot id: A0A0K2P596
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamC family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1159554:AFK67 RS16155
gene id: 1159554:AFK67_RS16155
uniprot id: A0A0K2P5W0
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

1159554:AFK67 RS12250
gene id: 1159554:AFK67_RS12250
uniprot id: A0A0K2P352
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family. LpxM subfamily.
messages: Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)-lipid A.
messages: Cell inner membrane

1159554:AFK67 RS05165
gene id: 1159554:AFK67_RS05165
uniprot id: A0A0K2NZB8
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS19485
gene id: 1159554:AFK67_RS19485
uniprot id: A0A0K2P6Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcrB family.
messages: Cell membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis. Essential for lipoprotein maturation under conditions where membrane fluidity may be altered.

1159554:AFK67 RS16215
gene id: 1159554:AFK67_RS16215
uniprot id: A0A0K2P571
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

1159554:AFK67 RS15555
gene id: 1159554:AFK67_RS15555
uniprot id: A0A0K2P4Z2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1159554:AFK67 RS03765
gene id: 1159554:AFK67_RS03765
uniprot id: A0A0K2P7S5
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS13935
gene id: 1159554:AFK67_RS13935
uniprot id: A0A0K2P4P9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1159554:AFK67 RS12660
gene id: 1159554:AFK67_RS12660
uniprot id: A0A0K2P444
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1159554:AFK67 RS12815
gene id: 1159554:AFK67_RS12815
uniprot id: A0A0K2P470
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Required for the assembly of the rivet at the earliest stage of flagellar biosynthesis.
messages: Role in flagellar biosynthesis.

1159554:AFK67 RS19645
gene id: 1159554:AFK67_RS19645
uniprot id: A0A0K2P767
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1159554:AFK67 RS12760
gene id: 1159554:AFK67_RS12760
uniprot id: A0A0K2P3K4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

1159554:AFK67 RS15585
gene id: 1159554:AFK67_RS15585
uniprot id: A0A0K2P4V8
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS08035
gene id: 1159554:AFK67_RS08035
uniprot id: A0A0K2P114
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

1159554:AFK67 RS17080
gene id: 1159554:AFK67_RS17080
uniprot id: A0A0K2P5N7
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1159554:AFK67 RS04255
gene id: 1159554:AFK67_RS04255
uniprot id: A0A0K2NYV4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

1159554:AFK67 RS01290
gene id: 1159554:AFK67_RS01290
uniprot id: A0A0K2NXA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 56 family.
messages: Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis.
messages: Cell inner membrane

1159554:AFK67 RS04480
gene id: 1159554:AFK67_RS04480
uniprot id: A0A0K2NZ56
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Binds 1 sodium ion per monomer.
messages: Binds 2 magnesium ions per monomer.
messages: Homotetramer.

1159554:AFK67 RS19555
gene id: 1159554:AFK67_RS19555
uniprot id: A0A0K2P6Z4
names: Subunit
messages: Monomer.

1159554:AFK67 RS06075
gene id: 1159554:AFK67_RS06075
uniprot id: A0A0K2P001
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1159554:AFK67 RS08065
gene id: 1159554:AFK67_RS08065
uniprot id: A0A0K2P0W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YkuD family.
messages: Periplasm

1159554:AFK67 RS06140
gene id: 1159554:AFK67_RS06140
uniprot id: A0A0K2P005
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1159554:AFK67 RS07690
gene id: 1159554:AFK67_RS07690
uniprot id: A0A0K2P0N8
names: Function
names: Similarity
messages: Belongs to the CsgG family.
messages: May be involved in the biogenesis of curli organelles.

1159554:AFK67 RS00910
gene id: 1159554:AFK67_RS00910
uniprot id: A0A0K2P7P3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Activates expression of the rhaBAD and rhaT operons.
messages: Binds DNA as a dimer.
messages: Cytoplasm

1159554:AFK67 RS13290
gene id: 1159554:AFK67_RS13290
uniprot id: A0A0K2P3U5
names: Similarity
messages: Belongs to the UPF0053 family.

1159554:AFK67 RS12475
gene id: 1159554:AFK67_RS12475
uniprot id: A0A0K2P3A4
names: Similarity
messages: Belongs to the MotB family.

1159554:AFK67 RS07625
gene id: 1159554:AFK67_RS07625
uniprot id: A0A0K2P0Q1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DyP-type peroxidase family. EfeB subfamily.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Homodimer. Part of a ferrous iron transporter composed of EfeU, EfeO and EfeB.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.
messages: Periplasm

1159554:AFK67 RS08605
gene id: 1159554:AFK67_RS08605
uniprot id: A0A0K2P181
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1159554:AFK67 RS15105
gene id: 1159554:AFK67_RS15105
uniprot id: A0A0K2P4L9
names: Similarity
messages: Belongs to the YfgM family.

1159554:AFK67 RS15425
gene id: 1159554:AFK67_RS15425
uniprot id: A0A0K2P5J5
names: Similarity
messages: Belongs to the thioredoxin family.

1159554:AFK67 RS02295
gene id: 1159554:AFK67_RS02295
uniprot id: A0A0K2P7L9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1159554:AFK67 RS06380
gene id: 1159554:AFK67_RS06380
uniprot id: A0A0K2NZZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1159554:AFK67 RS12260
gene id: 1159554:AFK67_RS12260
uniprot id: A0A0K2P3U7
names: Function
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.
messages: Involved in the high-affinity zinc uptake transport system.

1159554:AFK67 RS08905
gene id: 1159554:AFK67_RS08905
uniprot id: A0A0K2P1H3
names: Similarity
messages: Belongs to the Gfa family.

1159554:AFK67 RS04720
gene id: 1159554:AFK67_RS04720
uniprot id: A0A0K2NZ42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1159554:AFK67 RS08645
gene id: 1159554:AFK67_RS08645
uniprot id: A0A0K2P1C1
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1159554:AFK67 RS12775
gene id: 1159554:AFK67_RS12775
uniprot id: A0A0K2P3E6
names: Subcellular Location Annotation
messages: Cytoplasm

1159554:AFK67 RS20645
gene id: 1159554:AFK67_RS20645
uniprot id: A0A0K2P8Q5
names: Similarity
messages: Belongs to the DapA family.

1159554:AFK67 RS11710
gene id: 1159554:AFK67_RS11710
uniprot id: A0A0K2P3I1
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1159554:AFK67 RS03620
gene id: 1159554:AFK67_RS03620
uniprot id: A0A0K2NYH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1159554:AFK67 RS11790
gene id: 1159554:AFK67_RS11790
uniprot id: A0A0K2P2Z4
names: Similarity
messages: Belongs to the peptidase S41A family.

1159554:AFK67 RS06840
gene id: 1159554:AFK67_RS06840
uniprot id: A0A0K2P0A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS14200
gene id: 1159554:AFK67_RS14200
uniprot id: A0A0K2P4U2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1159554:AFK67 RS14805
gene id: 1159554:AFK67_RS14805
uniprot id: A0A0K2P4K6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylthioribose kinase family.
messages: Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.
messages: Homodimer.

1159554:AFK67 RS13425
gene id: 1159554:AFK67_RS13425
uniprot id: A0A0K2P3W8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1159554:AFK67 RS18120
gene id: 1159554:AFK67_RS18120
uniprot id: A0A0K2P6B9
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

1159554:AFK67 RS20070
gene id: 1159554:AFK67_RS20070
uniprot id: A0A0K2P7Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

1159554:AFK67 RS09260
gene id: 1159554:AFK67_RS09260
uniprot id: A0A0K2P295
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1159554:AFK67 RS07630
gene id: 1159554:AFK67_RS07630
uniprot id: A0A0K2P0U8
names: Similarity
messages: Belongs to the PhoH family.

1159554:AFK67 RS11280
gene id: 1159554:AFK67_RS11280
uniprot id: A0A0K2P2S2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1159554:AFK67 RS18225
gene id: 1159554:AFK67_RS18225
uniprot id: A0A0K2P704
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

1159554:AFK67 RS20165
gene id: 1159554:AFK67_RS20165
uniprot id: A0A0K2P7G8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

1159554:AFK67 RS07060
gene id: 1159554:AFK67_RS07060
uniprot id: A0A0K2P140
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Homotetramer.

1159554:AFK67 RS14640
gene id: 1159554:AFK67_RS14640
uniprot id: A0A0K2P4D0
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS07415
gene id: 1159554:AFK67_RS07415
uniprot id: A0A0K2P0R0
names: Similarity
messages: Belongs to the peptidase S16 family.

1159554:AFK67 RS01345
gene id: 1159554:AFK67_RS01345
uniprot id: A0A0K2NXJ3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1159554:AFK67 RS12485
gene id: 1159554:AFK67_RS12485
uniprot id: A0A0K2P3F6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhC family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.

1159554:AFK67 RS09965
gene id: 1159554:AFK67_RS09965
uniprot id: A0A0K2P238
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS03695
gene id: 1159554:AFK67_RS03695
uniprot id: A0A0K2NYJ4
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
messages: Repressed under conditions of excess protein secretion capacity and derepressed when protein secretion becomes limiting. This is regulated by SecM.

1159554:AFK67 RS17160
gene id: 1159554:AFK67_RS17160
uniprot id: A0A0K2P5U5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.

1159554:AFK67 RS18275
gene id: 1159554:AFK67_RS18275
uniprot id: A0A0K2P839
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. GltP subfamily.
messages: Catalyzes the proton-dependent transport of glutamate and aspartate.
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS07670
gene id: 1159554:AFK67_RS07670
uniprot id: A0A0K2P8E4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrA subfamily.
messages: Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
messages: Cytoplasm

1159554:AFK67 RS03950
gene id: 1159554:AFK67_RS03950
uniprot id: A0A0K2NYW4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

1159554:AFK67 RS00215
gene id: 1159554:AFK67_RS00215
uniprot id: A0A0K2NWY2
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

1159554:AFK67 RS15775
gene id: 1159554:AFK67_RS15775
uniprot id: A0A0K2P549
names: Similarity
messages: Belongs to the phage portal family. PBSX subfamily.

1159554:AFK67 RS20250
gene id: 1159554:AFK67_RS20250
uniprot id: A0A0K2P818
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1159554:AFK67 RS17730
gene id: 1159554:AFK67_RS17730
uniprot id: A0A0K2P625
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cytochrome b562 family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per molecule.
messages: Electron-transport protein of unknown function.

1159554:AFK67 RS16595
gene id: 1159554:AFK67_RS16595
uniprot id: A0A0K2P5I6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

1159554:AFK67 RS01845
gene id: 1159554:AFK67_RS01845
uniprot id: A0A0K2NXP7
names: Function
names: Similarity
names: Subunit
messages: Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters.
messages: Belongs to the transcriptional regulatory Fis family.
messages: Homodimer.

1159554:AFK67 RS05295
gene id: 1159554:AFK67_RS05295
uniprot id: A0A0K2NZE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1159554:AFK67 RS08690
gene id: 1159554:AFK67_RS08690
uniprot id: A0A0K2P1E4
names: Similarity
messages: Belongs to the HesB/IscA family.

1159554:AFK67 RS03420
gene id: 1159554:AFK67_RS03420
uniprot id: A0A0K2NYG9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1159554:AFK67 RS18110
gene id: 1159554:AFK67_RS18110
uniprot id: A0A0K2P6D4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.
messages: Homodimer.
messages: With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P.

1159554:AFK67 RS08260
gene id: 1159554:AFK67_RS08260
uniprot id: A0A0K2P164
names: Subcellular Location Annotation
messages: Cytoplasm

1159554:AFK67 RS07695
gene id: 1159554:AFK67_RS07695
uniprot id: A0A0K2P0R1
names: Function
messages: May be involved in the biogenesis of curli organelles.

1159554:AFK67 RS10490
gene id: 1159554:AFK67_RS10490
uniprot id: A0A0K2P2D5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1159554:AFK67 RS07970
gene id: 1159554:AFK67_RS07970
uniprot id: A0A0K2P0W8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1159554:AFK67 RS11515
gene id: 1159554:AFK67_RS11515
uniprot id: A0A0K2P2R0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility.
messages: Bacterial flagellum basal body
messages: Belongs to the YcgR family.
messages: Monomer. Interacts with the flagellar basal bodies.

1159554:AFK67 RS18650
gene id: 1159554:AFK67_RS18650
uniprot id: A0A0K2P6M8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

1159554:AFK67 RS19460
gene id: 1159554:AFK67_RS19460
uniprot id: A0A0K2P6Y4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1159554:AFK67 RS16975
gene id: 1159554:AFK67_RS16975
uniprot id: A0A0K2P5K5
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1159554:AFK67 RS11000
gene id: 1159554:AFK67_RS11000
uniprot id: A0A0K2P2M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS00935
gene id: 1159554:AFK67_RS00935
uniprot id: A0A0K2NXC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
messages: Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain.
messages: Cell membrane

1159554:AFK67 RS07770
gene id: 1159554:AFK67_RS07770
uniprot id: A0A0K2P0S4
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1159554:AFK67 RS18070
gene id: 1159554:AFK67_RS18070
uniprot id: A0A0K2P6D1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1159554:AFK67 RS13845
gene id: 1159554:AFK67_RS13845
uniprot id: A0A0K2P4N9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the rusA family.
messages: Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of CC dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of RuvAB or RuvC.
messages: Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC.
messages: Homodimer.

1159554:AFK67 RS08620
gene id: 1159554:AFK67_RS08620
uniprot id: A0A0K2P1B6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Vitamin B12 importer (TC 3.A.1.13.1) family.
messages: Cell membrane
messages: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (BtuD), two transmembrane proteins (BtuC) and a solute-binding protein (BtuF).

1159554:AFK67 RS08075
gene id: 1159554:AFK67_RS08075
uniprot id: A0A0K2P132
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1159554:AFK67 RS09365
gene id: 1159554:AFK67_RS09365
uniprot id: A0A0K2P2B5
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1159554:AFK67 RS02340
gene id: 1159554:AFK67_RS02340
uniprot id: A0A0K2NXU1
names: Function
names: Similarity
messages: Belongs to the UbiT family.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Likely functions as an accessory factor.

1159554:AFK67 RS14305
gene id: 1159554:AFK67_RS14305
uniprot id: A0A0K2P4B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

1159554:AFK67 RS01620
gene id: 1159554:AFK67_RS01620
uniprot id: A0A0K2NY59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1159554:AFK67 RS12505
gene id: 1159554:AFK67_RS12505
uniprot id: A0A0K2P3B7
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

1159554:AFK67 RS02225
gene id: 1159554:AFK67_RS02225
uniprot id: A0A0K2NXV9
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1159554:AFK67 RS19920
gene id: 1159554:AFK67_RS19920
uniprot id: A0A0K2P764
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

1159554:AFK67 RS16220
gene id: 1159554:AFK67_RS16220
uniprot id: A0A0K2P577
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

1159554:AFK67 RS17220
gene id: 1159554:AFK67_RS17220
uniprot id: A0A0K2P5U2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.

1159554:AFK67 RS05785
gene id: 1159554:AFK67_RS05785
uniprot id: A0A0K2P8D5
names: Similarity
messages: Belongs to the VgrG protein family.

1159554:AFK67 RS05330
gene id: 1159554:AFK67_RS05330
uniprot id: A0A0K2NZL8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1159554:AFK67 RS18835
gene id: 1159554:AFK67_RS18835
uniprot id: A0A0K2P6R4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1159554:AFK67 RS16435
gene id: 1159554:AFK67_RS16435
uniprot id: A0A0K2P5A5
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

1159554:AFK67 RS12795
gene id: 1159554:AFK67_RS12795
uniprot id: A0A0K2P3I8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1159554:AFK67 RS11730
gene id: 1159554:AFK67_RS11730
uniprot id: A0A0K2P302
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS20385
gene id: 1159554:AFK67_RS20385
uniprot id: A0A0K2P7J6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1159554:AFK67 RS16455
gene id: 1159554:AFK67_RS16455
uniprot id: A0A0K2P5E3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1159554:AFK67 RS12770
gene id: 1159554:AFK67_RS12770
uniprot id: A0A0K2P3I3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

1159554:AFK67 RS18905
gene id: 1159554:AFK67_RS18905
uniprot id: A0A0K2P6M1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1159554:AFK67 RS04005
gene id: 1159554:AFK67_RS04005
uniprot id: A0A0K2NYX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1159554:AFK67 RS16140
gene id: 1159554:AFK67_RS16140
uniprot id: A0A0K2P556
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AlaE exporter family.
messages: Cell inner membrane
messages: Exports L-alanine.

1159554:AFK67 RS07720
gene id: 1159554:AFK67_RS07720
uniprot id: A0A0K2P0R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CsgC/AgfC family.
messages: Periplasm

1159554:AFK67 RS01020
gene id: 1159554:AFK67_RS01020
uniprot id: A0A0K2NXU0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MetJ family.
messages: Cytoplasm
messages: Does not bind DNA by a helix-turn-helix motif.
messages: Homodimer.
messages: This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.

1159554:AFK67 RS14705
gene id: 1159554:AFK67_RS14705
uniprot id: A0A0K2P4I6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

1159554:AFK67 RS08695
gene id: 1159554:AFK67_RS08695
uniprot id: A0A0K2P1Y6
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1159554:AFK67 RS18000
gene id: 1159554:AFK67_RS18000
uniprot id: A0A0K2P6A0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

1159554:AFK67 RS11615
gene id: 1159554:AFK67_RS11615
uniprot id: A0A0K2P2R8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.
messages: Membrane

1159554:AFK67 RS13085
gene id: 1159554:AFK67_RS13085
uniprot id: A0A0K2P4B2
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1159554:AFK67 RS11880
gene id: 1159554:AFK67_RS11880
uniprot id: A0A0K2P333
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1159554:AFK67 RS04895
gene id: 1159554:AFK67_RS04895
uniprot id: A0A0K2NZC9
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS17265
gene id: 1159554:AFK67_RS17265
uniprot id: A0A0K2P6F2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

1159554:AFK67 RS17105
gene id: 1159554:AFK67_RS17105
uniprot id: A0A0K2P5P2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Monomer.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1159554:AFK67 RS03175
gene id: 1159554:AFK67_RS03175
uniprot id: A0A0K2NYF8
names: Similarity
messages: Belongs to the stealth family.

1159554:AFK67 RS03460
gene id: 1159554:AFK67_RS03460
uniprot id: A0A0K2NYL3
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

1159554:AFK67 RS15200
gene id: 1159554:AFK67_RS15200
uniprot id: A0A0K2P4R8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity. Interacts with IscU.

1159554:AFK67 RS04830
gene id: 1159554:AFK67_RS04830
uniprot id: A0A0K2NZD1
names: Similarity
messages: Belongs to the UPF0178 family.

1159554:AFK67 RS13685
gene id: 1159554:AFK67_RS13685
uniprot id: A0A0K2P3W7
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine synthase RsuA family.
messages: Monomer.

1159554:AFK67 RS12395
gene id: 1159554:AFK67_RS12395
uniprot id: A0A0K2P373
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1159554:AFK67 RS13110
gene id: 1159554:AFK67_RS13110
uniprot id: A0A0K2P4B7
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1159554:AFK67 RS02025
gene id: 1159554:AFK67_RS02025
uniprot id: A0A0K2NXV2
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

1159554:AFK67 RS04035
gene id: 1159554:AFK67_RS04035
uniprot id: A0A0K2NYX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1159554:AFK67 RS14880
gene id: 1159554:AFK67_RS14880
uniprot id: A0A0K2P4H3
names: Similarity
messages: Belongs to the isochorismate synthase family.

1159554:AFK67 RS12735
gene id: 1159554:AFK67_RS12735
uniprot id: A0A0K2P455
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1159554:AFK67 RS05975
gene id: 1159554:AFK67_RS05975
uniprot id: A0A0K2NZY2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1159554:AFK67 RS01725
gene id: 1159554:AFK67_RS01725
uniprot id: A0A0K2NXQ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1159554:AFK67 RS00615
gene id: 1159554:AFK67_RS00615
uniprot id: A0A0K2NX79
names: Similarity
messages: Belongs to the RHS family.

1159554:AFK67 RS20515
gene id: 1159554:AFK67_RS20515
uniprot id: A0A0K2P7H9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

1159554:AFK67 RS07740
gene id: 1159554:AFK67_RS07740
uniprot id: A0A0K2P0P8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyltransferase 3 family. OpgC subfamily.
messages: Cell membrane
messages: Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane.

1159554:AFK67 RS12705
gene id: 1159554:AFK67_RS12705
uniprot id: A0A0K2P3J5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1159554:AFK67 RS03970
gene id: 1159554:AFK67_RS03970
uniprot id: A0A0K2NYS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dGTPase family. Type 1 subfamily.
messages: Homotetramer.
messages: dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs.

1159554:AFK67 RS17615
gene id: 1159554:AFK67_RS17615
uniprot id: A0A0K2P6M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS05805
gene id: 1159554:AFK67_RS05805
uniprot id: A0A0K2NZU4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1159554:AFK67 RS17255
gene id: 1159554:AFK67_RS17255
uniprot id: A0A0K2P5S2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

1159554:AFK67 RS15190
gene id: 1159554:AFK67_RS15190
uniprot id: A0A0K2P4S7
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1159554:AFK67 RS06650
gene id: 1159554:AFK67_RS06650
uniprot id: A0A0K2P0A4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

1159554:AFK67 RS17445
gene id: 1159554:AFK67_RS17445
uniprot id: A0A0K2P600
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
messages: Monomer.

1159554:AFK67 RS19145
gene id: 1159554:AFK67_RS19145
uniprot id: A0A0K2P6X2
names: Subcellular Location Annotation
messages: Cell inner membrane

1159554:AFK67 RS07260
gene id: 1159554:AFK67_RS07260
uniprot id: A0A0K2P0N1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1159554:AFK67 RS12185
gene id: 1159554:AFK67_RS12185
uniprot id: A0A0K2P3T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopC family.
messages: Involved in copper resistance. Appears to be involved in copper uptake.
messages: Periplasm

1159554:AFK67 RS18855
gene id: 1159554:AFK67_RS18855
uniprot id: A0A0K2NY59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1159554:AFK67 RS00985
gene id: 1159554:AFK67_RS00985
uniprot id: A0A0K2NX91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1159554:AFK67 RS09295
gene id: 1159554:AFK67_RS09295
uniprot id: A0A0K2P1N8
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS16680
gene id: 1159554:AFK67_RS16680
uniprot id: A0A0K2P5K0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1159554:AFK67 RS08090
gene id: 1159554:AFK67_RS08090
uniprot id: A0A0K2P0W6
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family. NagK subfamily.
messages: Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P.

1159554:AFK67 RS03445
gene id: 1159554:AFK67_RS03445
uniprot id: A0A0K2NYH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefC subfamily.
messages: Cell inner membrane
messages: Homodimer. Interacts with the regulatory subunit KefF.
messages: Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.

1159554:AFK67 RS01415
gene id: 1159554:AFK67_RS01415
uniprot id: A0A0K2NXG8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

1159554:AFK67 RS03280
gene id: 1159554:AFK67_RS03280
uniprot id: A0A0K2NZ03
names: Similarity
messages: Belongs to the threonine synthase family.

1159554:AFK67 RS05075
gene id: 1159554:AFK67_RS05075
uniprot id: A0A0K2NZG5
names: Similarity
messages: Belongs to the BolA/IbaG family.

1159554:AFK67 RS07320
gene id: 1159554:AFK67_RS07320
uniprot id: A0A0K2P0N9
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1159554:AFK67 RS18715
gene id: 1159554:AFK67_RS18715
uniprot id: A0A0K2P783
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1159554:AFK67 RS04015
gene id: 1159554:AFK67_RS04015
uniprot id: A0A0K2NYW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1159554:AFK67 RS03455
gene id: 1159554:AFK67_RS03455
uniprot id: A0A0K2NZ37
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1159554:AFK67 RS05605
gene id: 1159554:AFK67_RS05605
uniprot id: A0A0K2NZQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1159554:AFK67 RS00010
gene id: 1159554:AFK67_RS00010
uniprot id: A0A0K2NWS3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1159554:AFK67 RS20785
gene id: 1159554:AFK67_RS20785
uniprot id: A0A0K2P857
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1159554:AFK67 RS01190
gene id: 1159554:AFK67_RS01190
uniprot id: A0A0K2NX87
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1159554:AFK67 RS11580
gene id: 1159554:AFK67_RS11580
uniprot id: A0A0K2P2V5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
messages: Cell membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1159554:AFK67 RS01635
gene id: 1159554:AFK67_RS01635
uniprot id: A0A0K2NXJ9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1159554:AFK67 RS14180
gene id: 1159554:AFK67_RS14180
uniprot id: A0A0K2P449
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1159554:AFK67 RS02945
gene id: 1159554:AFK67_RS02945
uniprot id: A0A0K2NYC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

1159554:AFK67 RS04285
gene id: 1159554:AFK67_RS04285
uniprot id: A0A0K2NYY3
names: Function
names: Similarity
messages: Belongs to the FrsA family.
messages: Catalyzes the hydrolysis of esters.

1159554:AFK67 RS03470
gene id: 1159554:AFK67_RS03470
uniprot id: A0A0K2NYH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1159554:AFK67 RS03995
gene id: 1159554:AFK67_RS03995
uniprot id: A0A0K2NYQ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1159554:AFK67 RS00945
gene id: 1159554:AFK67_RS00945
uniprot id: A0A0K2NXB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1159554:AFK67 RS14280
gene id: 1159554:AFK67_RS14280
uniprot id: A0A0K2P4A9
names: Similarity
messages: Belongs to the GST superfamily.

1159554:AFK67 RS08000
gene id: 1159554:AFK67_RS08000
uniprot id: A0A0K2P118
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1159554:AFK67 RS02700
gene id: 1159554:AFK67_RS02700
uniprot id: A0A0K2NY85
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1159554:AFK67 RS01965
gene id: 1159554:AFK67_RS01965
uniprot id: A0A0K2NYD9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1159554:AFK67 RS08870
gene id: 1159554:AFK67_RS08870
uniprot id: A0A0K2P220
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family. RcnA subfamily.
messages: Cell membrane
messages: Efflux system for nickel and cobalt.
messages: Membrane

1159554:AFK67 RS11525
gene id: 1159554:AFK67_RS11525
uniprot id: A0A0K2P3E4
names: Similarity
messages: Belongs to the peptidase S66 family.

1159554:AFK67 RS05000
gene id: 1159554:AFK67_RS05000
uniprot id: A0A0K2NZF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1159554:AFK67 RS12870
gene id: 1159554:AFK67_RS12870
uniprot id: A0A0K2P7Z8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1159554:AFK67 RS05985
gene id: 1159554:AFK67_RS05985
uniprot id: A0A0K2NZY0
names: Similarity
messages: Belongs to the UPF0250 family.

1159554:AFK67 RS16785
gene id: 1159554:AFK67_RS16785
uniprot id: A0A0K2P661
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1159554:AFK67 RS12480
gene id: 1159554:AFK67_RS12480
uniprot id: A0A0K2P3B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1159554:AFK67 RS07910
gene id: 1159554:AFK67_RS07910
uniprot id: A0A0K2P0Z0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

1159554:AFK67 RS06240
gene id: 1159554:AFK67_RS06240
uniprot id: A0A0K2P026
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1159554:AFK67 RS10850
gene id: 1159554:AFK67_RS10850
uniprot id: A0A0K2P349
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

1159554:AFK67 RS17405
gene id: 1159554:AFK67_RS17405
uniprot id: A0A0K2P5U7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1159554:AFK67 RS20990
gene id: 1159554:AFK67_RS20990
uniprot id: A0A0K2P891
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

1159554:AFK67 RS07585
gene id: 1159554:AFK67_RS07585
uniprot id: A0A0K2P1F0
names: Function
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family. RutA subfamily.
messages: Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism, adding oxygen atoms in the process to yield ureidoacrylate peracid, that immediately reacts with FMN forming ureidoacrylate and FMN-N(5)-oxide. The FMN-N(5)-oxide reacts spontaneously with NADH to produce FMN. Requires the flavin reductase RutF to regenerate FMN in vivo.

1159554:AFK67 RS01375
gene id: 1159554:AFK67_RS01375
uniprot id: A0A0K2NY13
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD, in which XerC interacts with XerD via its C-terminal region, XerD interacts with XerC via its C-terminal region and so on.
messages: FtsK may regulate the catalytic switch between XerC and XerD in the heterotetrameric complex during the two steps of the recombination process.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerC specifically exchanges the top DNA strands.

1159554:AFK67 RS04605
gene id: 1159554:AFK67_RS04605
uniprot id: A0A0K2NZT5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1159554:AFK67 RS05315
gene id: 1159554:AFK67_RS05315
uniprot id: A0A0K2NZK6
names: Similarity
messages: Belongs to the Hha/YmoA/Cnu family.

1159554:AFK67 RS19140
gene id: 1159554:AFK67_RS19140
uniprot id: A0A0K2P6S6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Monomer.

1159554:AFK67 RS17785
gene id: 1159554:AFK67_RS17785
uniprot id: A0A0K2P635
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1159554:AFK67 RS06080
gene id: 1159554:AFK67_RS06080
uniprot id: A0A0K2P0I6
names: Similarity
messages: Belongs to the PhoH family.

1159554:AFK67 RS03380
gene id: 1159554:AFK67_RS03380
uniprot id: A0A0K2NZ21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1159554:AFK67 RS10305
gene id: 1159554:AFK67_RS10305
uniprot id: A0A0K2P250
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1159554:AFK67 RS18735
gene id: 1159554:AFK67_RS18735
uniprot id: A0A0K2P6P4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1159554:AFK67 RS01630
gene id: 1159554:AFK67_RS01630
uniprot id: A0A0K2NXG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NusG family.
messages: Monomer. Interacts with the transcription termination factor Rho and with RNA polymerase.
messages: Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination.

1159554:AFK67 RS05960
gene id: 1159554:AFK67_RS05960
uniprot id: A0A0K2NZX5
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1159554:AFK67 RS02245
gene id: 1159554:AFK67_RS02245
uniprot id: A0A0K2NXS6
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1159554:AFK67 RS06655
gene id: 1159554:AFK67_RS06655
uniprot id: A0A0K2P043
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1159554:AFK67 RS09120
gene id: 1159554:AFK67_RS09120
uniprot id: A0A0K2P265
names: Similarity
messages: Belongs to the peptidase C40 family.

1159554:AFK67 RS06625
gene id: 1159554:AFK67_RS06625
uniprot id: A0A0K2P099
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS03685
gene id: 1159554:AFK67_RS03685
uniprot id: A0A0K2NZ84
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1159554:AFK67 RS05870
gene id: 1159554:AFK67_RS05870
uniprot id: A0A0K2NZS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1159554:AFK67 RS00040
gene id: 1159554:AFK67_RS00040
uniprot id: A0A0K2NWX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1159554:AFK67 RS18455
gene id: 1159554:AFK67_RS18455
uniprot id: A0A0K2P6E2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1159554:AFK67 RS14955
gene id: 1159554:AFK67_RS14955
uniprot id: A0A0K2P4I7
names: Similarity
messages: Belongs to the ArsC family.

1159554:AFK67 RS11205
gene id: 1159554:AFK67_RS11205
uniprot id: A0A0K2P3A2
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

1159554:AFK67 RS06005
gene id: 1159554:AFK67_RS06005
uniprot id: A0A0K2P0G9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

1159554:AFK67 RS06020
gene id: 1159554:AFK67_RS06020
uniprot id: A0A0K2NZU8
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1159554:AFK67 RS05910
gene id: 1159554:AFK67_RS05910
uniprot id: A0A0K2NZW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1159554:AFK67 RS03285
gene id: 1159554:AFK67_RS03285
uniprot id: A0A0K2NYH7
names: Similarity
messages: Belongs to the UPF0246 family.

1159554:AFK67 RS06975
gene id: 1159554:AFK67_RS06975
uniprot id: A0A0K2P0D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1159554:AFK67 RS06765
gene id: 1159554:AFK67_RS06765
uniprot id: A0A0K2P0C8
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS10765
gene id: 1159554:AFK67_RS10765
uniprot id: A0A0K2P2D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1159554:AFK67 RS01815
gene id: 1159554:AFK67_RS01815
uniprot id: A0A0K2NXL5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1159554:AFK67 RS19915
gene id: 1159554:AFK67_RS19915
uniprot id: A0A0K2P798
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

1159554:AFK67 RS17315
gene id: 1159554:AFK67_RS17315
uniprot id: A0A0K2P6G3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1159554:AFK67 RS17290
gene id: 1159554:AFK67_RS17290
uniprot id: A0A0K2P6F8
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

1159554:AFK67 RS08990
gene id: 1159554:AFK67_RS08990
uniprot id: A0A0K2P1D5
names: Similarity
messages: Belongs to the VgrG protein family.

1159554:AFK67 RS08295
gene id: 1159554:AFK67_RS08295
uniprot id: A0A0K2P158
names: Similarity
messages: Belongs to the CTP synthase family.

1159554:AFK67 RS05100
gene id: 1159554:AFK67_RS05100
uniprot id: A0A0K2NZH0
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1159554:AFK67 RS18725
gene id: 1159554:AFK67_RS18725
uniprot id: A0A0K2P6I4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1159554:AFK67 RS12765
gene id: 1159554:AFK67_RS12765
uniprot id: A0A0K2P460
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1159554:AFK67 RS20075
gene id: 1159554:AFK67_RS20075
uniprot id: A0A0K2P7C9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.

1159554:AFK67 RS16340
gene id: 1159554:AFK67_RS16340
uniprot id: A0A0K2P5E1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the UbiD family. YclC subfamily.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Involved in the non-oxidative decarboxylation and detoxification of phenolic derivatives.

1159554:AFK67 RS19055
gene id: 1159554:AFK67_RS19055
uniprot id: A0A0K2P6Q2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1159554:AFK67 RS01705
gene id: 1159554:AFK67_RS01705
uniprot id: A0A0K2NXK3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1159554:AFK67 RS20220
gene id: 1159554:AFK67_RS20220
uniprot id: A0A0K2P813
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1159554:AFK67 RS11435
gene id: 1159554:AFK67_RS11435
uniprot id: A0A0K2P2U4
names: Similarity
messages: Belongs to the GST superfamily.

1159554:AFK67 RS19960
gene id: 1159554:AFK67_RS19960
uniprot id: A0A0K2P7V8
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1159554:AFK67 RS09070
gene id: 1159554:AFK67_RS09070
uniprot id: A0A0K2P1J8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Multidrug efflux pump that functions probably as a Na(+)/drug antiporter.

1159554:AFK67 RS07990
gene id: 1159554:AFK67_RS07990
uniprot id: A0A0K2P0U7
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1159554:AFK67 RS10865
gene id: 1159554:AFK67_RS10865
uniprot id: A0A0K2P2F0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: Homodimer.

1159554:AFK67 RS04945
gene id: 1159554:AFK67_RS04945
uniprot id: A0A0K2NZZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family.
messages: Cell outer membrane

1159554:AFK67 RS01010
gene id: 1159554:AFK67_RS01010
uniprot id: A0A0K2NX96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1159554:AFK67 RS01740
gene id: 1159554:AFK67_RS01740
uniprot id: A0A0K2NXS8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1159554:AFK67 RS18140
gene id: 1159554:AFK67_RS18140
uniprot id: A0A0K2P6E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS04540
gene id: 1159554:AFK67_RS04540
uniprot id: A0A0K2NZ36
names: Function
names: Similarity
messages: Belongs to the IolE/MocC family.
messages: Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol).

1159554:AFK67 RS04665
gene id: 1159554:AFK67_RS04665
uniprot id: A0A0K2NZ34
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS16610
gene id: 1159554:AFK67_RS16610
uniprot id: A0A0K2P5E2
names: Function
messages: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.

1159554:AFK67 RS19185
gene id: 1159554:AFK67_RS19185
uniprot id: A0A0K2P6S7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
messages: Cytoplasm
messages: Monomer.
messages: The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.

1159554:AFK67 RS11610
gene id: 1159554:AFK67_RS11610
uniprot id: A0A0K2P2W1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

1159554:AFK67 RS05585
gene id: 1159554:AFK67_RS05585
uniprot id: A0A0K2NZR3
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

1159554:AFK67 RS18190
gene id: 1159554:AFK67_RS18190
uniprot id: A0A0K2P6E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane
messages: Responsible for the transport of C4-dicarboxylates.

1159554:AFK67 RS14700
gene id: 1159554:AFK67_RS14700
uniprot id: A0A0K2P4D7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1159554:AFK67 RS09215
gene id: 1159554:AFK67_RS09215
uniprot id: A0A0K2P1J5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxine kinase family. PdxY subfamily.
messages: Homodimer.
messages: Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP.

1159554:AFK67 RS02220
gene id: 1159554:AFK67_RS02220
uniprot id: A0A0K2NXS1
names: Similarity
messages: Belongs to the peptidase S13 family.

1159554:AFK67 RS16880
gene id: 1159554:AFK67_RS16880
uniprot id: A0A0K2P5J4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD, in which XerC interacts with XerD via its C-terminal region, XerD interacts with XerC via its C-terminal region and so on.
messages: FtsK may regulate the catalytic switch between XerC and XerD in the heterotetrameric complex during the two steps of the recombination process.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerC binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerD specifically exchanges the bottom DNA strands.

1159554:AFK67 RS18445
gene id: 1159554:AFK67_RS18445
uniprot id: A0A0K2P743
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS07840
gene id: 1159554:AFK67_RS07840
uniprot id: A0A0K2P0R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

1159554:AFK67 RS14050
gene id: 1159554:AFK67_RS14050
uniprot id: A0A0K2P426
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

1159554:AFK67 RS04815
gene id: 1159554:AFK67_RS04815
uniprot id: A0A0K2NZB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1159554:AFK67 RS15385
gene id: 1159554:AFK67_RS15385
uniprot id: A0A0K2P4T1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1159554:AFK67 RS06320
gene id: 1159554:AFK67_RS06320
uniprot id: A0A0K2P0M9
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: The heme is bound between the two transmembrane subunits.

1159554:AFK67 RS07620
gene id: 1159554:AFK67_RS07620
uniprot id: A0A0K2P0M8
names: Function
names: Similarity
messages: Belongs to the EfeM/EfeO family.
messages: Involved in Fe(2+) uptake. Could be an iron-binding and/or electron-transfer component.

1159554:AFK67 RS17060
gene id: 1159554:AFK67_RS17060
uniprot id: A0A0K2P5S5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SprT family.
messages: Binds 1 zinc ion.
messages: Cytoplasm

1159554:AFK67 RS17655
gene id: 1159554:AFK67_RS17655
uniprot id: A0A0K2P610
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS07300
gene id: 1159554:AFK67_RS07300
uniprot id: A0A0K2P0H6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family. MukB subfamily.
messages: Homodimerization via its hinge domain. Binds to DNA via its C-terminal region. Interacts, and probably forms a ternary complex, with MukE and MukF via its C-terminal region. The complex formation is stimulated by calcium or magnesium. Interacts with tubulin-related protein FtsZ.
messages: Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.
messages: The hinge domain, which separates the large intramolecular coiled coil regions, allows the homodimerization, forming a V-shaped homodimer.
messages: nucleoid

1159554:AFK67 RS18095
gene id: 1159554:AFK67_RS18095
uniprot id: A0A0K2P6B4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1159554:AFK67 RS13060
gene id: 1159554:AFK67_RS13060
uniprot id: A0A0K2P4A7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1159554:AFK67 RS02190
gene id: 1159554:AFK67_RS02190
uniprot id: A0A0K2NXY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1159554:AFK67 RS15215
gene id: 1159554:AFK67_RS15215
uniprot id: A0A0K2P4T2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

1159554:AFK67 RS00655
gene id: 1159554:AFK67_RS00655
uniprot id: A0A0K2P878
names: Similarity
messages: Belongs to the VgrG protein family.

1159554:AFK67 RS01585
gene id: 1159554:AFK67_RS01585
uniprot id: A0A0K2NXG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1159554:AFK67 RS09095
gene id: 1159554:AFK67_RS09095
uniprot id: A0A0K2P260
names: Similarity
messages: Belongs to the CFA/CMAS family.

1159554:AFK67 RS15560
gene id: 1159554:AFK67_RS15560
uniprot id: A0A0K2P4V3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1159554:AFK67 RS08470
gene id: 1159554:AFK67_RS08470
uniprot id: A0A0K2P136
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

1159554:AFK67 RS20100
gene id: 1159554:AFK67_RS20100
uniprot id: A0A0K2P7D5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1159554:AFK67 RS14175
gene id: 1159554:AFK67_RS14175
uniprot id: A0A0K2P8J7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1159554:AFK67 RS05385
gene id: 1159554:AFK67_RS05385
uniprot id: A0A0K2P073
names: Similarity
messages: Belongs to the CdaR family.

1159554:AFK67 RS16640
gene id: 1159554:AFK67_RS16640
uniprot id: A0A0K2P5H5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

1159554:AFK67 RS11565
gene id: 1159554:AFK67_RS11565
uniprot id: A0A0K2P2S0
names: Function
names: Similarity
messages: Belongs to the DadA oxidoreductase family.
messages: Oxidative deamination of D-amino acids.

1159554:AFK67 RS07480
gene id: 1159554:AFK67_RS07480
uniprot id: A0A0K2P1D3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Interacts with the TusBCD complex. Interacts with MnmA.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Could accept sulfur from TusD.

1159554:AFK67 RS15295
gene id: 1159554:AFK67_RS15295
uniprot id: A0A0K2P4W6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

1159554:AFK67 RS07790
gene id: 1159554:AFK67_RS07790
uniprot id: A0A0K2P0Q8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MSOX/MTOX family. MTOX subfamily.
messages: Binds 1 FAD per subunit.
messages: Catalyzes the oxidative demethylation of N-methyl-L-tryptophan.
messages: Monomer.

1159554:AFK67 RS15450
gene id: 1159554:AFK67_RS15450
uniprot id: A0A0K2P5J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Metabolite:H+ Symporter (MHS) family (TC 2.A.1.6) family.
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS08100
gene id: 1159554:AFK67_RS08100
uniprot id: A0A0K2P137
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

1159554:AFK67 RS05645
gene id: 1159554:AFK67_RS05645
uniprot id: A0A0K2NZS3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1159554:AFK67 RS11795
gene id: 1159554:AFK67_RS11795
uniprot id: A0A0K2P2V3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ProQ family.
messages: Cytoplasm
messages: RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism.

1159554:AFK67 RS03315
gene id: 1159554:AFK67_RS03315
uniprot id: A0A0K2NYB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

1159554:AFK67 RS09440
gene id: 1159554:AFK67_RS09440
uniprot id: A0A0K2P2D1
names: Similarity
messages: Belongs to the glycosyl hydrolase 51 family.

1159554:AFK67 RS18990
gene id: 1159554:AFK67_RS18990
uniprot id: A0A0K2P6U1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1159554:AFK67 RS16425
gene id: 1159554:AFK67_RS16425
uniprot id: A0A0K2P602
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1159554:AFK67 RS09860
gene id: 1159554:AFK67_RS09860
uniprot id: A0A0K2P1X5
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS17170
gene id: 1159554:AFK67_RS17170
uniprot id: A0A0K2P5T3
names: Similarity
messages: Belongs to the fabD family.

1159554:AFK67 RS15150
gene id: 1159554:AFK67_RS15150
uniprot id: A0A0K2P4Q8
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

1159554:AFK67 RS08435
gene id: 1159554:AFK67_RS08435
uniprot id: A0A0K2P1U3
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family. AstD subfamily.
messages: Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.

1159554:AFK67 RS12730
gene id: 1159554:AFK67_RS12730
uniprot id: A0A0K2P3J9
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1159554:AFK67 RS04065
gene id: 1159554:AFK67_RS04065
uniprot id: A0A0K2NZG6
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1159554:AFK67 RS19780
gene id: 1159554:AFK67_RS19780
uniprot id: A0A0K2P772
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

1159554:AFK67 RS13530
gene id: 1159554:AFK67_RS13530
uniprot id: A0A0K2P3Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Galactose/methyl galactoside importer (TC 3.A.1.2.3) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system.
messages: The complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

1159554:AFK67 RS07580
gene id: 1159554:AFK67_RS07580
uniprot id: A0A0K2P0U0
names: Function
names: Similarity
messages: Belongs to the isochorismatase family. RutB subfamily.
messages: Hydrolyzes ureidoacrylate to form aminoacrylate and carbamate. The carbamate hydrolyzes spontaneously, thereby releasing one of the nitrogen atoms of the pyrimidine ring as ammonia and one of its carbon atoms as CO2.

1159554:AFK67 RS20320
gene id: 1159554:AFK67_RS20320
uniprot id: A0A0K2P7F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

1159554:AFK67 RS11640
gene id: 1159554:AFK67_RS11640
uniprot id: A0A0K2P2W5
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

1159554:AFK67 RS03945
gene id: 1159554:AFK67_RS03945
uniprot id: A0A0K2NYS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chloride channel (TC 2.A.49) family. ClcA subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Membrane
messages: Proton-coupled chloride transporter. Functions as antiport system and exchanges two chloride ions for 1 proton. Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response.

1159554:AFK67 RS01520
gene id: 1159554:AFK67_RS01520
uniprot id: A0A0K2NXI6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

1159554:AFK67 RS15275
gene id: 1159554:AFK67_RS15275
uniprot id: A0A0K2P4U7
names: Similarity
messages: Belongs to the P(II) protein family.

1159554:AFK67 RS15095
gene id: 1159554:AFK67_RS15095
uniprot id: A0A0K2P4Q0
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1159554:AFK67 RS04755
gene id: 1159554:AFK67_RS04755
uniprot id: A0A0K2NZB7
names: Function
names: Similarity
messages: Belongs to the IprA family.
messages: Involved in oxidative stress resistance.

1159554:AFK67 RS00095
gene id: 1159554:AFK67_RS00095
uniprot id: A0A0K2NXE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS15510
gene id: 1159554:AFK67_RS15510
uniprot id: A0A0K2P4U4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamA, the core component of the assembly machinery.

1159554:AFK67 RS02275
gene id: 1159554:AFK67_RS02275
uniprot id: A0A0K2NYI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1159554:AFK67 RS11720
gene id: 1159554:AFK67_RS11720
uniprot id: A0A0K2P2T9
names: Similarity
messages: Belongs to the UPF0053 family.

1159554:AFK67 RS10815
gene id: 1159554:AFK67_RS10815
uniprot id: A0A0K2P2E2
names: Subcellular Location Annotation
messages: Cytoplasm

1159554:AFK67 RS15625
gene id: 1159554:AFK67_RS15625
uniprot id: A0A0K2P5M7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1159554:AFK67 RS15600
gene id: 1159554:AFK67_RS15600
uniprot id: A0A0K2P5M3
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1159554:AFK67 RS05255
gene id: 1159554:AFK67_RS05255
uniprot id: A0A0K2P051
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1159554:AFK67 RS02120
gene id: 1159554:AFK67_RS02120
uniprot id: A0A0K2NXQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

1159554:AFK67 RS05410
gene id: 1159554:AFK67_RS05410
uniprot id: A0A0K2P077
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

1159554:AFK67 RS08195
gene id: 1159554:AFK67_RS08195
uniprot id: A0A0K2P0Y7
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS20760
gene id: 1159554:AFK67_RS20760
uniprot id: A0A0K2P854
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1159554:AFK67 RS18730
gene id: 1159554:AFK67_RS18730
uniprot id: A0A0K2P6K0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1159554:AFK67 RS11505
gene id: 1159554:AFK67_RS11505
uniprot id: A0A0K2P2T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1159554:AFK67 RS05030
gene id: 1159554:AFK67_RS05030
uniprot id: A0A0K2NZ93
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1159554:AFK67 RS16780
gene id: 1159554:AFK67_RS16780
uniprot id: A0A0K2P5M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1159554:AFK67 RS10015
gene id: 1159554:AFK67_RS10015
uniprot id: A0A0K2P247
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

1159554:AFK67 RS10685
gene id: 1159554:AFK67_RS10685
uniprot id: A0A0K2P2B9
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

1159554:AFK67 RS16965
gene id: 1159554:AFK67_RS16965
uniprot id: A0A0K2P687
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1159554:AFK67 RS17110
gene id: 1159554:AFK67_RS17110
uniprot id: A0A0K2P5T5
names: Similarity
messages: Belongs to the YggT family.

1159554:AFK67 RS14720
gene id: 1159554:AFK67_RS14720
uniprot id: A0A0K2P4E0
names: Subcellular Location Annotation
messages: Cytoplasm

1159554:AFK67 RS04635
gene id: 1159554:AFK67_RS04635
uniprot id: A0A0K2NZ83
names: Subunit
messages: Homodimer.

1159554:AFK67 RS16995
gene id: 1159554:AFK67_RS16995
uniprot id: A0A0K2P5P9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysE/ArgO transporter (TC 2.A.75) family.
messages: Cell membrane
messages: Involved in the export of arginine. Important to control the intracellular level of arginine and the correct balance between arginine and lysine.
messages: Membrane

1159554:AFK67 RS04740
gene id: 1159554:AFK67_RS04740
uniprot id: A0A0K2NZA0
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1159554:AFK67 RS01405
gene id: 1159554:AFK67_RS01405
uniprot id: A0A0K2NXI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1159554:AFK67 RS02300
gene id: 1159554:AFK67_RS02300
uniprot id: A0A0K2NY17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1159554:AFK67 RS17375
gene id: 1159554:AFK67_RS17375
uniprot id: A0A0K2P5X3
names: Similarity
messages: Belongs to the lycopene cyclase family.

1159554:AFK67 RS03905
gene id: 1159554:AFK67_RS03905
uniprot id: A0A0K2NZD2
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1159554:AFK67 RS18465
gene id: 1159554:AFK67_RS18465
uniprot id: A0A0K2P6J8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

1159554:AFK67 RS08480
gene id: 1159554:AFK67_RS08480
uniprot id: A0A0K2P1A3
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

1159554:AFK67 RS07885
gene id: 1159554:AFK67_RS07885
uniprot id: A0A0K2P0Y5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1159554:AFK67 RS05890
gene id: 1159554:AFK67_RS05890
uniprot id: A0A0K2NZP8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rnk family.
messages: Interacts with the RNA polymerase.
messages: May act as an anti-Gre factor.

1159554:AFK67 RS01250
gene id: 1159554:AFK67_RS01250
uniprot id: A0A0K2NXI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WzzB/Cld/Rol family.
messages: Cell inner membrane
messages: Membrane
messages: Modulates the polysaccharide chain length of enterobacterial common antigen (ECA).
messages: Probably part of a complex composed of WzxE, WzyE and WzzE.

1159554:AFK67 RS11070
gene id: 1159554:AFK67_RS11070
uniprot id: A0A0K2P2I0
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1159554:AFK67 RS11075
gene id: 1159554:AFK67_RS11075
uniprot id: A0A0K2P2J2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the RssB family.
messages: Binds to RpoS.
messages: Phosphorylated. Phosphorylation stimulates the interaction with RpoS and, therefore, the proteolysis of RpoS.
messages: Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co-degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation.

1159554:AFK67 RS12435
gene id: 1159554:AFK67_RS12435
uniprot id: A0A0K2P3C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

1159554:AFK67 RS08915
gene id: 1159554:AFK67_RS08915
uniprot id: A0A0K2P1E2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1159554:AFK67 RS17470
gene id: 1159554:AFK67_RS17470
uniprot id: A0A0K2P604
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HpcH/HpaI aldolase family. Citrate lyase beta subunit subfamily.
messages: Cytoplasm
messages: Oligomer with a subunit composition of (alpha,beta,gamma)6.
messages: Represents a citryl-ACP lyase.

1159554:AFK67 RS06370
gene id: 1159554:AFK67_RS06370
uniprot id: A0A0K2P0P2
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1159554:AFK67 RS19885
gene id: 1159554:AFK67_RS19885
uniprot id: A0A0K2P7U2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1159554:AFK67 RS17195
gene id: 1159554:AFK67_RS17195
uniprot id: A0A0K2P5T7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MdcC family.
messages: Covalently binds the prosthetic group of malonate decarboxylase.
messages: Cytoplasm
messages: Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism.

1159554:AFK67 RS17505
gene id: 1159554:AFK67_RS17505
uniprot id: A0A0K2P6K2
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1159554:AFK67 RS19615
gene id: 1159554:AFK67_RS19615
uniprot id: A0A0K2P763
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. Pit subfamily.
messages: Membrane

1159554:AFK67 RS00015
gene id: 1159554:AFK67_RS00015
uniprot id: A0A0K2NWX0
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS12755
gene id: 1159554:AFK67_RS12755
uniprot id: A0A0K2P3F3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1159554:AFK67 RS05200
gene id: 1159554:AFK67_RS05200
uniprot id: A0A0K2NZJ4
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

1159554:AFK67 RS20375
gene id: 1159554:AFK67_RS20375
uniprot id: A0A0K2P7K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0761 family.
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS07915
gene id: 1159554:AFK67_RS07915
uniprot id: A0A0K2P0T3
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS12675
gene id: 1159554:AFK67_RS12675
uniprot id: A0A0K2P3E1
names: Function
names: Similarity
messages: Belongs to the LuxC family.
messages: LuxC is the fatty acid reductase enzyme responsible for synthesis of the aldehyde substrate for the luminescent reaction catalyzed by luciferase.

1159554:AFK67 RS07120
gene id: 1159554:AFK67_RS07120
uniprot id: A0A0K2P0E9
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1159554:AFK67 RS14340
gene id: 1159554:AFK67_RS14340
uniprot id: A0A0K2P481
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedD family.
messages: Cell inner membrane
messages: Non-essential cell division protein that could be required for efficient cell constriction.
messages: The SPOR domain binds septal peptidoglycans and is required to target DedD to the septal ring.

1159554:AFK67 RS18720
gene id: 1159554:AFK67_RS18720
uniprot id: A0A0K2P6M2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1159554:AFK67 RS18480
gene id: 1159554:AFK67_RS18480
uniprot id: A0A0K2P6I6
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the porin LamB (TC 1.B.3) family.
messages: By maltose.
messages: Cell outer membrane
messages: Homotrimer formed of three 18-stranded antiparallel beta-barrels, containing three independent channels.
messages: Involved in the transport of maltose and maltodextrins.
messages: Membrane

1159554:AFK67 RS02250
gene id: 1159554:AFK67_RS02250
uniprot id: A0A0K2NXW3
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1159554:AFK67 RS00510
gene id: 1159554:AFK67_RS00510
uniprot id: A0A0K2NX62
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1159554:AFK67 RS18740
gene id: 1159554:AFK67_RS18740
uniprot id: A0A0K2P787
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1159554:AFK67 RS03155
gene id: 1159554:AFK67_RS03155
uniprot id: A0A0K2NY84
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

1159554:AFK67 RS00980
gene id: 1159554:AFK67_RS00980
uniprot id: A0A0K2NX50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraA family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.
messages: Homotrimer. Binds to both RNA-binding sites in the C-terminal region of Rne and to RhlB.

1159554:AFK67 RS09885
gene id: 1159554:AFK67_RS09885
uniprot id: A0A0K2P1Y0
names: Similarity
messages: Belongs to the peptidase C40 family.

1159554:AFK67 RS08105
gene id: 1159554:AFK67_RS08105
uniprot id: A0A0K2P1P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1159554:AFK67 RS13305
gene id: 1159554:AFK67_RS13305
uniprot id: A0A0K2P3N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

1159554:AFK67 RS04485
gene id: 1159554:AFK67_RS04485
uniprot id: A0A0K2NZ08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Oligosaccharide:H(+) symporter (OHS) (TC 2.A.1.5) family.
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS14460
gene id: 1159554:AFK67_RS14460
uniprot id: A0A0K2P4D8
names: Similarity
messages: Belongs to the MlaA family.

1159554:AFK67 RS08005
gene id: 1159554:AFK67_RS08005
uniprot id: A0A0K2P1M2
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS10140
gene id: 1159554:AFK67_RS10140
uniprot id: A0A0K2P1Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0187 family.
messages: Membrane

1159554:AFK67 RS03700
gene id: 1159554:AFK67_RS03700
uniprot id: A0A0K2NYM6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1159554:AFK67 RS18355
gene id: 1159554:AFK67_RS18355
uniprot id: A0A0K2P6D8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1159554:AFK67 RS20105
gene id: 1159554:AFK67_RS20105
uniprot id: A0A0K2P7A0
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1159554:AFK67 RS14295
gene id: 1159554:AFK67_RS14295
uniprot id: A0A0K2P4C0
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

1159554:AFK67 RS02255
gene id: 1159554:AFK67_RS02255
uniprot id: A0A0K2NY12
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1159554:AFK67 RS07920
gene id: 1159554:AFK67_RS07920
uniprot id: A0A0K2P0V6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1159554:AFK67 RS05520
gene id: 1159554:AFK67_RS05520
uniprot id: A0A0K2NZI7
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1159554:AFK67 RS08655
gene id: 1159554:AFK67_RS08655
uniprot id: A0A0K2P192
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

1159554:AFK67 RS06085
gene id: 1159554:AFK67_RS06085
uniprot id: A0A0K2NZZ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1159554:AFK67 RS13075
gene id: 1159554:AFK67_RS13075
uniprot id: A0A0K2P3K6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Equilibrium between an active dimeric form, an inactive hexameric form and higher aggregates. Interconversion between the various forms is largely reversible and is influenced by the natural substrates and inhibitors of the enzyme.
messages: Feedback inhibited by histidine.

1159554:AFK67 RS00055
gene id: 1159554:AFK67_RS00055
uniprot id: A0A0K2NWN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1159554:AFK67 RS18815
gene id: 1159554:AFK67_RS18815
uniprot id: A0A0K2P7A2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1159554:AFK67 RS08220
gene id: 1159554:AFK67_RS08220
uniprot id: A0A0K2P7U3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Cell membrane
messages: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1159554:AFK67 RS17300
gene id: 1159554:AFK67_RS17300
uniprot id: A0A0K2P5S7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.
messages: Homooctamer.

1159554:AFK67 RS00835
gene id: 1159554:AFK67_RS00835
uniprot id: A0A0K2NX66
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 4 [4Fe-4S] clusters per subunit.
messages: Membrane
messages: The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.

1159554:AFK67 RS19680
gene id: 1159554:AFK67_RS19680
uniprot id: A0A0K2P753
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Metabolite:H+ Symporter (MHS) family (TC 2.A.1.6) family.
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS01930
gene id: 1159554:AFK67_RS01930
uniprot id: A0A0K2NXQ8
names: Similarity
messages: Belongs to the RNase E/G family. RNase G subfamily.

1159554:AFK67 RS07125
gene id: 1159554:AFK67_RS07125
uniprot id: A0A0K2P0H7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1159554:AFK67 RS19720
gene id: 1159554:AFK67_RS19720
uniprot id: A0A0K2P784
names: Similarity
messages: Belongs to the glycosyl hydrolase 8 (cellulase D) family.

1159554:AFK67 RS07805
gene id: 1159554:AFK67_RS07805
uniprot id: A0A0K2P1I5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

1159554:AFK67 RS08660
gene id: 1159554:AFK67_RS08660
uniprot id: A0A0K2P1D9
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1159554:AFK67 RS06335
gene id: 1159554:AFK67_RS06335
uniprot id: A0A0K2P006
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1159554:AFK67 RS17760
gene id: 1159554:AFK67_RS17760
uniprot id: A0A0K2P8L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

1159554:AFK67 RS03275
gene id: 1159554:AFK67_RS03275
uniprot id: A0A0K2NYI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1159554:AFK67 RS08040
gene id: 1159554:AFK67_RS08040
uniprot id: A0A0K2P0V7
names: Similarity
messages: Belongs to the UPF0227 family.

1159554:AFK67 RS00270
gene id: 1159554:AFK67_RS00270
uniprot id: A0A0K2NWR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1159554:AFK67 RS13355
gene id: 1159554:AFK67_RS13355
uniprot id: A0A0K2P3T5
names: Subcellular Location Annotation
messages: Cell inner membrane

1159554:AFK67 RS07340
gene id: 1159554:AFK67_RS07340
uniprot id: A0A0K2P1B0
names: Similarity
messages: Belongs to the peptidase M1 family.

1159554:AFK67 RS15860
gene id: 1159554:AFK67_RS15860
uniprot id: A0A0K2P511
names: Similarity
messages: Belongs to the peptidase S24 family.

1159554:AFK67 RS07455
gene id: 1159554:AFK67_RS07455
uniprot id: A0A0K2P0R2
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

1159554:AFK67 RS03085
gene id: 1159554:AFK67_RS03085
uniprot id: A0A0K2NYA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1159554:AFK67 RS18215
gene id: 1159554:AFK67_RS18215
uniprot id: A0A0K2P6B5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family. RcnA subfamily.
messages: Cell membrane
messages: Efflux system for nickel and cobalt.
messages: Membrane

1159554:AFK67 RS03210
gene id: 1159554:AFK67_RS03210
uniprot id: A0A0K2NYG3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1159554:AFK67 RS05625
gene id: 1159554:AFK67_RS05625
uniprot id: A0A0K2P0B1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1159554:AFK67 RS13990
gene id: 1159554:AFK67_RS13990
uniprot id: A0A0K2P446
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1159554:AFK67 RS12580
gene id: 1159554:AFK67_RS12580
uniprot id: A0A0K2P3C9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1159554:AFK67 RS15210
gene id: 1159554:AFK67_RS15210
uniprot id: A0A0K2P4N8
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

1159554:AFK67 RS19410
gene id: 1159554:AFK67_RS19410
uniprot id: A0A0K2P7Z9
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1159554:AFK67 RS07110
gene id: 1159554:AFK67_RS07110
uniprot id: A0A0K2P166
names: Subcellular Location Annotation
messages: Cytoplasm

1159554:AFK67 RS17380
gene id: 1159554:AFK67_RS17380
uniprot id: A0A0K2P5U3
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1159554:AFK67 RS07165
gene id: 1159554:AFK67_RS07165
uniprot id: A0A0K2P0L0
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

1159554:AFK67 RS07485
gene id: 1159554:AFK67_RS07485
uniprot id: A0A0K2P0R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1159554:AFK67 RS10465
gene id: 1159554:AFK67_RS10465
uniprot id: A0A0K2P2D2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1159554:AFK67 RS17500
gene id: 1159554:AFK67_RS17500
uniprot id: A0A0K2P609
names: Subcellular Location Annotation
messages: Cytoplasm

1159554:AFK67 RS15615
gene id: 1159554:AFK67_RS15615
uniprot id: A0A0K2P4W3
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

1159554:AFK67 RS00850
gene id: 1159554:AFK67_RS00850
uniprot id: A0A0K2NX95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1159554:AFK67 RS01200
gene id: 1159554:AFK67_RS01200
uniprot id: A0A0K2NXH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1159554:AFK67 RS10625
gene id: 1159554:AFK67_RS10625
uniprot id: A0A0K2P286
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

1159554:AFK67 RS21190
gene id: 1159554:AFK67_RS21190
uniprot id: A0A0K2P8F8
names: Similarity
messages: Belongs to the DinB family.

1159554:AFK67 RS14455
gene id: 1159554:AFK67_RS14455
uniprot id: A0A0K2P7X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1159554:AFK67 RS13055
gene id: 1159554:AFK67_RS13055
uniprot id: A0A0K2P3Q1
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS10965
gene id: 1159554:AFK67_RS10965
uniprot id: A0A0K2P2G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0259 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS03500
gene id: 1159554:AFK67_RS03500
uniprot id: A0A0K2NYM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

1159554:AFK67 RS18780
gene id: 1159554:AFK67_RS18780
uniprot id: A0A0K2P6L0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1159554:AFK67 RS13960
gene id: 1159554:AFK67_RS13960
uniprot id: A0A0K2P4Q2
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase family.

1159554:AFK67 RS11870
gene id: 1159554:AFK67_RS11870
uniprot id: A0A0K2P2W7
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS14860
gene id: 1159554:AFK67_RS14860
uniprot id: A0A0K2P4L7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioesterase PaaI family.
messages: Cytoplasm
messages: Homotetramer. Dimer of dimers. Interacts specifically with the aryl carrier protein (ArCP) domain of EntB.
messages: Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules.

1159554:AFK67 RS02370
gene id: 1159554:AFK67_RS02370
uniprot id: A0A0K2NXY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS15410
gene id: 1159554:AFK67_RS15410
uniprot id: A0A0K2P4T5
names: Function
messages: Acts as a radical domain for damaged PFL and possibly other radical proteins.

1159554:AFK67 RS00825
gene id: 1159554:AFK67_RS00825
uniprot id: A0A0K2NX90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhE family.
messages: Cytoplasm
messages: Necessary for formate dehydrogenase activity.

1159554:AFK67 RS01430
gene id: 1159554:AFK67_RS01430
uniprot id: A0A0K2NXJ1
names: Similarity
messages: Belongs to the Rht family.

1159554:AFK67 RS02000
gene id: 1159554:AFK67_RS02000
uniprot id: A0A0K2NXN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

1159554:AFK67 RS07145
gene id: 1159554:AFK67_RS07145
uniprot id: A0A0K2P0F4
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1159554:AFK67 RS21305
gene id: 1159554:AFK67_RS21305
uniprot id: A0A0K2P911
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS16945
gene id: 1159554:AFK67_RS16945
uniprot id: A0A0K2P5N9
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1159554:AFK67 RS04790
gene id: 1159554:AFK67_RS04790
uniprot id: A0A0K2NZB0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1159554:AFK67 RS02310
gene id: 1159554:AFK67_RS02310
uniprot id: A0A0K2NY02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

1159554:AFK67 RS16170
gene id: 1159554:AFK67_RS16170
uniprot id: A0A0K2P567
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

1159554:AFK67 RS08720
gene id: 1159554:AFK67_RS08720
uniprot id: A0A0K2P1Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YkuD family.
messages: Periplasm

1159554:AFK67 RS10520
gene id: 1159554:AFK67_RS10520
uniprot id: A0A0K2P2D8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1159554:AFK67 RS07220
gene id: 1159554:AFK67_RS07220
uniprot id: A0A0K2P0G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1159554:AFK67 RS07710
gene id: 1159554:AFK67_RS07710
uniprot id: A0A0K2P0V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CsgA/CsgB family.
messages: Fimbrium

1159554:AFK67 RS13570
gene id: 1159554:AFK67_RS13570
uniprot id: A0A0K2P4J2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1159554:AFK67 RS16295
gene id: 1159554:AFK67_RS16295
uniprot id: A0A0K2P581
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS18685
gene id: 1159554:AFK67_RS18685
uniprot id: A0A0K2P6N2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS02480
gene id: 1159554:AFK67_RS02480
uniprot id: A0A0K2NY30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS11295
gene id: 1159554:AFK67_RS11295
uniprot id: A0A0K2P2L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS20155
gene id: 1159554:AFK67_RS20155
uniprot id: A0A0K2P7B1
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS12560
gene id: 1159554:AFK67_RS12560
uniprot id: A0A0K2P3H1
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS07175
gene id: 1159554:AFK67_RS07175
uniprot id: A0A0K2P0I4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. YcaD (TC 2.A.1.26) family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1159554:AFK67 RS17230
gene id: 1159554:AFK67_RS17230
uniprot id: A0A0K2P5R7
names: Function
names: Similarity
names: Subunit
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.
messages: Homodimer.

1159554:AFK67 RS00595
gene id: 1159554:AFK67_RS00595
uniprot id: A0A0K2NXM4
names: Similarity
messages: Belongs to the VgrG protein family.

1159554:AFK67 RS03560
gene id: 1159554:AFK67_RS03560
uniprot id: A0A0K2NZ55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Set transporter family.
messages: Membrane

1159554:AFK67 RS01885
gene id: 1159554:AFK67_RS01885
uniprot id: A0A0K2NXU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1159554:AFK67 RS02355
gene id: 1159554:AFK67_RS02355
uniprot id: A0A0K2NYK3
names: Similarity
messages: Belongs to the UPF0306 family.

1159554:AFK67 RS01165
gene id: 1159554:AFK67_RS01165
uniprot id: A0A0K2NX83
names: Function
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.
messages: Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.

1159554:AFK67 RS04060
gene id: 1159554:AFK67_RS04060
uniprot id: A0A0K2NYY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1159554:AFK67 RS05380
gene id: 1159554:AFK67_RS05380
uniprot id: A0A0K2NZM8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1159554:AFK67 RS06220
gene id: 1159554:AFK67_RS06220
uniprot id: A0A0K2P0K6
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1159554:AFK67 RS04545
gene id: 1159554:AFK67_RS04545
uniprot id: A0A0K2NZ80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS17050
gene id: 1159554:AFK67_RS17050
uniprot id: A0A0K2P5M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Cell inner membrane
messages: Membrane

1159554:AFK67 RS19835
gene id: 1159554:AFK67_RS19835
uniprot id: A0A0K2P7T1
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1159554:AFK67 RS06430
gene id: 1159554:AFK67_RS06430
uniprot id: A0A0K2NZZ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1159554:AFK67 RS17085
gene id: 1159554:AFK67_RS17085
uniprot id: A0A0K2P5T0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1159554:AFK67 RS09665
gene id: 1159554:AFK67_RS09665
uniprot id: A0A0K2P1R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1159554:AFK67 RS20740
gene id: 1159554:AFK67_RS20740
uniprot id: A0A0K2P889
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

1159554:AFK67 RS02150
gene id: 1159554:AFK67_RS02150
uniprot id: A0A0K2NXU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

1159554:AFK67 RS09320
gene id: 1159554:AFK67_RS09320
uniprot id: A0A0K2P1P3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1159554:AFK67 RS13535
gene id: 1159554:AFK67_RS13535
uniprot id: A0A0K2P4I9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

1159554:AFK67 RS02065
gene id: 1159554:AFK67_RS02065
uniprot id: A0A0K2NXP6
names: Function
names: Similarity
messages: Belongs to the peptidase C56 family.
messages: Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate.

1159554:AFK67 RS00325
gene id: 1159554:AFK67_RS00325
uniprot id: A0A0K2NWY1
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS08490
gene id: 1159554:AFK67_RS08490
uniprot id: A0A0K2P190
names: Subcellular Location Annotation
messages: Membrane

1159554:AFK67 RS14620
gene id: 1159554:AFK67_RS14620
uniprot id: A0A0K2P4C7
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1159554:AFK67 RS05515
gene id: 1159554:AFK67_RS05515
uniprot id: A0A0K2NZP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1159554:AFK67 RS00275
gene id: 1159554:AFK67_RS00275
uniprot id: A0A0K2NWX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1159554:AFK67 RS06770
gene id: 1159554:AFK67_RS06770
uniprot id: A0A0K2P0X8
names: Function
names: Similarity
messages: Belongs to the DtxR/MntR family.
messages: In the presence of manganese, represses expression of mntH and mntS. Up-regulates expression of mntP.