114881:EXC37 RS02205
gene id: 114881:EXC37_RS02205
uniprot id: A0A449B8V6
names: Similarity
messages: Belongs to the XFP family.

114881:EXC37 RS00985
gene id: 114881:EXC37_RS00985
uniprot id: A0A449B884
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).

114881:EXC37 RS01730
gene id: 114881:EXC37_RS01730
uniprot id: A0A449B8K7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

114881:EXC37 RS00970
gene id: 114881:EXC37_RS00970
uniprot id: A0A449B860
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

114881:EXC37 RS03070
gene id: 114881:EXC37_RS03070
uniprot id: A0A449B9A6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

114881:EXC37 RS00475
gene id: 114881:EXC37_RS00475
uniprot id: A0A449B7X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Membrane

114881:EXC37 RS02930
gene id: 114881:EXC37_RS02930
uniprot id: A0A449B999
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

114881:EXC37 RS02590
gene id: 114881:EXC37_RS02590
uniprot id: A0A449B914
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

114881:EXC37 RS02470
gene id: 114881:EXC37_RS02470
uniprot id: A0A449B8Z8
names: Subcellular Location Annotation
messages: Membrane

114881:EXC37 RS00145
gene id: 114881:EXC37_RS00145
uniprot id: A0A449B7R8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

114881:EXC37 RS00045
gene id: 114881:EXC37_RS00045
uniprot id: A0A449B7N5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

114881:EXC37 RS00025
gene id: 114881:EXC37_RS00025
uniprot id: A0A449B7P2
names: Subcellular Location Annotation
messages: Membrane

114881:EXC37 RS02910
gene id: 114881:EXC37_RS02910
uniprot id: A0A449B976
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

114881:EXC37 RS00265
gene id: 114881:EXC37_RS00265
uniprot id: A0A449B7T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

114881:EXC37 RS02805
gene id: 114881:EXC37_RS02805
uniprot id: A0A449B955
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

114881:EXC37 RS02895
gene id: 114881:EXC37_RS02895
uniprot id: A0A449B971
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

114881:EXC37 RS02670
gene id: 114881:EXC37_RS02670
uniprot id: A0A449B941
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

114881:EXC37 RS00445
gene id: 114881:EXC37_RS00445
uniprot id: A0A449B7W7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

114881:EXC37 RS01590
gene id: 114881:EXC37_RS01590
uniprot id: A0A449B8I6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

114881:EXC37 RS02780
gene id: 114881:EXC37_RS02780
uniprot id: A0A449B966
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

114881:EXC37 RS02535
gene id: 114881:EXC37_RS02535
uniprot id: A0A449B905
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

114881:EXC37 RS02305
gene id: 114881:EXC37_RS02305
uniprot id: A0A449B8X6
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

114881:EXC37 RS02775
gene id: 114881:EXC37_RS02775
uniprot id: A0A449B962
names: Similarity
messages: Belongs to the HPrK/P family.

114881:EXC37 RS01610
gene id: 114881:EXC37_RS01610
uniprot id: A0A449B8H4
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

114881:EXC37 RS00950
gene id: 114881:EXC37_RS00950
uniprot id: A0A449B880
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

114881:EXC37 RS00825
gene id: 114881:EXC37_RS00825
uniprot id: A0A449B836
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

114881:EXC37 RS02705
gene id: 114881:EXC37_RS02705
uniprot id: A0A449B936
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

114881:EXC37 RS01110
gene id: 114881:EXC37_RS01110
uniprot id: A0A449B899
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

114881:EXC37 RS00505
gene id: 114881:EXC37_RS00505
uniprot id: A0A449B801
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

114881:EXC37 RS01360
gene id: 114881:EXC37_RS01360
uniprot id: A0A449B8D4
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

114881:EXC37 RS02115
gene id: 114881:EXC37_RS02115
uniprot id: A0A449B8U0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

114881:EXC37 RS01250
gene id: 114881:EXC37_RS01250
uniprot id: A0A449B8D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

114881:EXC37 RS02265
gene id: 114881:EXC37_RS02265
uniprot id: A0A449B8Y1
names: Similarity
messages: Belongs to the CTP synthase family.

114881:EXC37 RS02945
gene id: 114881:EXC37_RS02945
uniprot id: A0A449B979
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

114881:EXC37 RS02280
gene id: 114881:EXC37_RS02280
uniprot id: A0A449B8W5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

114881:EXC37 RS00715
gene id: 114881:EXC37_RS00715
uniprot id: A0A449B831
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

114881:EXC37 RS02345
gene id: 114881:EXC37_RS02345
uniprot id: A0A449B8X9
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

114881:EXC37 RS02495
gene id: 114881:EXC37_RS02495
uniprot id: A0A449B923
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

114881:EXC37 RS00815
gene id: 114881:EXC37_RS00815
uniprot id: A0A449B851
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

114881:EXC37 RS00810
gene id: 114881:EXC37_RS00810
uniprot id: A0A449B841
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

114881:EXC37 RS00510
gene id: 114881:EXC37_RS00510
uniprot id: A0A449B7Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

114881:EXC37 RS02635
gene id: 114881:EXC37_RS02635
uniprot id: A0A449B922
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

114881:EXC37 RS00990
gene id: 114881:EXC37_RS00990
uniprot id: A0A449B866
names: Subcellular Location Annotation
messages: Membrane

114881:EXC37 RS02450
gene id: 114881:EXC37_RS02450
uniprot id: A0A449B8Z3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

114881:EXC37 RS00095
gene id: 114881:EXC37_RS00095
uniprot id: A0A449B7Q7
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

114881:EXC37 RS00790
gene id: 114881:EXC37_RS00790
uniprot id: A0A449B840
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

114881:EXC37 RS01810
gene id: 114881:EXC37_RS01810
uniprot id: A0A449B8P4
names: Similarity
messages: Belongs to the peptidase S16 family.

114881:EXC37 RS02515
gene id: 114881:EXC37_RS02515
uniprot id: A0A449B911
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

114881:EXC37 RS00775
gene id: 114881:EXC37_RS00775
uniprot id: A0A449B826
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

114881:EXC37 RS02390
gene id: 114881:EXC37_RS02390
uniprot id: A0A449B8Y4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

114881:EXC37 RS00240
gene id: 114881:EXC37_RS00240
uniprot id: A0A449B7V3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

114881:EXC37 RS00750
gene id: 114881:EXC37_RS00750
uniprot id: A0A449B828
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

114881:EXC37 RS01200
gene id: 114881:EXC37_RS01200
uniprot id: A0A449B8C2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

114881:EXC37 RS00485
gene id: 114881:EXC37_RS00485
uniprot id: A0A449B7Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

114881:EXC37 RS00955
gene id: 114881:EXC37_RS00955
uniprot id: A0A449B872
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

114881:EXC37 RS00760
gene id: 114881:EXC37_RS00760
uniprot id: A0A449B829
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

114881:EXC37 RS00160
gene id: 114881:EXC37_RS00160
uniprot id: A0A449B7R5
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

114881:EXC37 RS02180
gene id: 114881:EXC37_RS02180
uniprot id: A0A449B8T8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

114881:EXC37 RS01420
gene id: 114881:EXC37_RS01420
uniprot id: A0A449B8H0
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

114881:EXC37 RS01985
gene id: 114881:EXC37_RS01985
uniprot id: A0A449B8P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

114881:EXC37 RS00910
gene id: 114881:EXC37_RS00910
uniprot id: A0A449B857
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

114881:EXC37 RS02920
gene id: 114881:EXC37_RS02920
uniprot id: A0A449B997
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

114881:EXC37 RS01615
gene id: 114881:EXC37_RS01615
uniprot id: A0A449B8I9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

114881:EXC37 RS00110
gene id: 114881:EXC37_RS00110
uniprot id: A0A449B7Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

114881:EXC37 RS02300
gene id: 114881:EXC37_RS02300
uniprot id: A0A449B8Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

114881:EXC37 RS02595
gene id: 114881:EXC37_RS02595
uniprot id: A0A449B916
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

114881:EXC37 RS01705
gene id: 114881:EXC37_RS01705
uniprot id: A0A449B8L8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

114881:EXC37 RS00520
gene id: 114881:EXC37_RS00520
uniprot id: A0A449B7Z0
names: Subcellular Location Annotation
messages: Membrane

114881:EXC37 RS00055
gene id: 114881:EXC37_RS00055
uniprot id: A0A449B7P4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

114881:EXC37 RS00155
gene id: 114881:EXC37_RS00155
uniprot id: A0A449B7S2
names: Similarity
messages: Belongs to the ClpA/ClpB family.

114881:EXC37 RS00585
gene id: 114881:EXC37_RS00585
uniprot id: A0A449B7Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

114881:EXC37 RS01335
gene id: 114881:EXC37_RS01335
uniprot id: A0A449B8E2
names: Similarity
messages: Belongs to the carbamate kinase family.

114881:EXC37 RS00415
gene id: 114881:EXC37_RS00415
uniprot id: A0A449B7V4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

114881:EXC37 RS00745
gene id: 114881:EXC37_RS00745
uniprot id: A0A449B816
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

114881:EXC37 RS02985
gene id: 114881:EXC37_RS02985
uniprot id: A0A449B9A9
names: Subcellular Location Annotation
messages: Membrane

114881:EXC37 RS00725
gene id: 114881:EXC37_RS00725
uniprot id: A0A449B815
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

114881:EXC37 RS00770
gene id: 114881:EXC37_RS00770
uniprot id: A0A449B845
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

114881:EXC37 RS02430
gene id: 114881:EXC37_RS02430
uniprot id: A0A449B8Z6
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

114881:EXC37 RS00400
gene id: 114881:EXC37_RS00400
uniprot id: A0A449B7W9
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

114881:EXC37 RS02980
gene id: 114881:EXC37_RS02980
uniprot id: A0A449B9A3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

114881:EXC37 RS01235
gene id: 114881:EXC37_RS01235
uniprot id: A0A449B8C5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

114881:EXC37 RS00500
gene id: 114881:EXC37_RS00500
uniprot id: A0A449B7Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

114881:EXC37 RS03100
gene id: 114881:EXC37_RS03100
uniprot id: A0A449B9C2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

114881:EXC37 RS02145
gene id: 114881:EXC37_RS02145
uniprot id: A0A449B8V5
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

114881:EXC37 RS00800
gene id: 114881:EXC37_RS00800
uniprot id: A0A449B838
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

114881:EXC37 RS01130
gene id: 114881:EXC37_RS01130
uniprot id: A0A449B8B3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

114881:EXC37 RS00440
gene id: 114881:EXC37_RS00440
uniprot id: A0A449B7Y4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

114881:EXC37 RS00625
gene id: 114881:EXC37_RS00625
uniprot id: A0A449B7Z4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

114881:EXC37 RS01085
gene id: 114881:EXC37_RS01085
uniprot id: A0A449B889
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

114881:EXC37 RS02625
gene id: 114881:EXC37_RS02625
uniprot id: A0A449B930
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

114881:EXC37 RS01065
gene id: 114881:EXC37_RS01065
uniprot id: A0A449B881
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

114881:EXC37 RS00965
gene id: 114881:EXC37_RS00965
uniprot id: A0A449B867
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

114881:EXC37 RS02510
gene id: 114881:EXC37_RS02510
uniprot id: A0A449B917
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

114881:EXC37 RS01165
gene id: 114881:EXC37_RS01165
uniprot id: A0A449B895
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

114881:EXC37 RS02230
gene id: 114881:EXC37_RS02230
uniprot id: A0A449B8U9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

114881:EXC37 RS02240
gene id: 114881:EXC37_RS02240
uniprot id: A0A449B8W0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

114881:EXC37 RS02750
gene id: 114881:EXC37_RS02750
uniprot id: A0A449B944
names: Subcellular Location Annotation
messages: Membrane

114881:EXC37 RS02850
gene id: 114881:EXC37_RS02850
uniprot id: A0A449B963
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

114881:EXC37 RS01540
gene id: 114881:EXC37_RS01540
uniprot id: A0A449B8H6
names: Subcellular Location Annotation
messages: Membrane

114881:EXC37 RS01755
gene id: 114881:EXC37_RS01755
uniprot id: A0A449B8N3
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

114881:EXC37 RS00530
gene id: 114881:EXC37_RS00530
uniprot id: A0A449B7Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

114881:EXC37 RS02940
gene id: 114881:EXC37_RS02940
uniprot id: A0A449B992
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

114881:EXC37 RS02055
gene id: 114881:EXC37_RS02055
uniprot id: A0A449B8T2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

114881:EXC37 RS00580
gene id: 114881:EXC37_RS00580
uniprot id: A0A449B7Z8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

114881:EXC37 RS01780
gene id: 114881:EXC37_RS01780
uniprot id: A0A449B8K5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

114881:EXC37 RS02610
gene id: 114881:EXC37_RS02610
uniprot id: A0A449B931
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

114881:EXC37 RS00010
gene id: 114881:EXC37_RS00010
uniprot id: A0A449B7N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta sliding clamp family.
messages: Cytoplasm

114881:EXC37 RS00165
gene id: 114881:EXC37_RS00165
uniprot id: A0A449B7R6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

114881:EXC37 RS01990
gene id: 114881:EXC37_RS01990
uniprot id: A0A449B8Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

114881:EXC37 RS01525
gene id: 114881:EXC37_RS01525
uniprot id: A0A449B8G6
names: Similarity
messages: Belongs to the LDH/MDH superfamily.

114881:EXC37 RS02140
gene id: 114881:EXC37_RS02140
uniprot id: A0A449B8T9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

114881:EXC37 RS02960
gene id: 114881:EXC37_RS02960
uniprot id: A0A449B985
names: Similarity
messages: Belongs to the IMPACT family.

114881:EXC37 RS00050
gene id: 114881:EXC37_RS00050
uniprot id: A0A449B7Q3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

114881:EXC37 RS01745
gene id: 114881:EXC37_RS01745
uniprot id: A0A449B8L7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

114881:EXC37 RS00555
gene id: 114881:EXC37_RS00555
uniprot id: A0A449B811
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

114881:EXC37 RS00210
gene id: 114881:EXC37_RS00210
uniprot id: A0A449B7S6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

114881:EXC37 RS00315
gene id: 114881:EXC37_RS00315
uniprot id: A0A449B7U8
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.

114881:EXC37 RS02675
gene id: 114881:EXC37_RS02675
uniprot id: A0A449B939
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

114881:EXC37 RS00005
gene id: 114881:EXC37_RS00005
uniprot id: A0A449B7N4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

114881:EXC37 RS02250
gene id: 114881:EXC37_RS02250
uniprot id: A0A449B8X1
names: Subcellular Location Annotation
messages: Membrane

114881:EXC37 RS01145
gene id: 114881:EXC37_RS01145
uniprot id: A0A449B8B4
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

114881:EXC37 RS03025
gene id: 114881:EXC37_RS03025
uniprot id: A0A449B9C0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

114881:EXC37 RS03005
gene id: 114881:EXC37_RS03005
uniprot id: A0A449B990
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

114881:EXC37 RS01340
gene id: 114881:EXC37_RS01340
uniprot id: A0A449B8E5
names: Subcellular Location Annotation
messages: Membrane

114881:EXC37 RS00780
gene id: 114881:EXC37_RS00780
uniprot id: A0A449B844
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

114881:EXC37 RS02320
gene id: 114881:EXC37_RS02320
uniprot id: A0A449B8Y3
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

114881:EXC37 RS02825
gene id: 114881:EXC37_RS02825
uniprot id: A0A449B974
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

114881:EXC37 RS00385
gene id: 114881:EXC37_RS00385
uniprot id: A0A449B7W8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

114881:EXC37 RS00620
gene id: 114881:EXC37_RS00620
uniprot id: A0A449B808
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

114881:EXC37 RS02680
gene id: 114881:EXC37_RS02680
uniprot id: A0A449B947
names: Subcellular Location Annotation
messages: Membrane

114881:EXC37 RS00115
gene id: 114881:EXC37_RS00115
uniprot id: A0A449B7R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

114881:EXC37 RS02020
gene id: 114881:EXC37_RS02020
uniprot id: A0A449B8R1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

114881:EXC37 RS02525
gene id: 114881:EXC37_RS02525
uniprot id: A0A449B903
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

114881:EXC37 RS01735
gene id: 114881:EXC37_RS01735
uniprot id: A0A449B8L4
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

114881:EXC37 RS02295
gene id: 114881:EXC37_RS02295
uniprot id: A0A449B8W9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

114881:EXC37 RS00295
gene id: 114881:EXC37_RS00295
uniprot id: A0A449B7U9
names: Similarity
messages: Belongs to the ATPase gamma chain family.

114881:EXC37 RS01410
gene id: 114881:EXC37_RS01410
uniprot id: A0A449B8E3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

114881:EXC37 RS02520
gene id: 114881:EXC37_RS02520
uniprot id: A0A449B907
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

114881:EXC37 RS02830
gene id: 114881:EXC37_RS02830
uniprot id: A0A449B978
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

114881:EXC37 RS00590
gene id: 114881:EXC37_RS00590
uniprot id: A0A449B802
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

114881:EXC37 RS01330
gene id: 114881:EXC37_RS01330
uniprot id: A0A449B8E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

114881:EXC37 RS01865
gene id: 114881:EXC37_RS01865
uniprot id: A0A449B8P1
names: Similarity
messages: Belongs to the peptidase M13 family.

114881:EXC37 RS02580
gene id: 114881:EXC37_RS02580
uniprot id: A0A449B918
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

114881:EXC37 RS03040
gene id: 114881:EXC37_RS03040
uniprot id: A0A449B9B1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

114881:EXC37 RS00805
gene id: 114881:EXC37_RS00805
uniprot id: A0A449B834
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

114881:EXC37 RS02500
gene id: 114881:EXC37_RS02500
uniprot id: A0A449B908
names: Similarity
messages: Belongs to the pyruvate kinase family.

114881:EXC37 RS01700
gene id: 114881:EXC37_RS01700
uniprot id: A0A449B8L1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

114881:EXC37 RS02585
gene id: 114881:EXC37_RS02585
uniprot id: A0A449B913
names: Similarity
messages: Belongs to the thioredoxin family.

114881:EXC37 RS02090
gene id: 114881:EXC37_RS02090
uniprot id: A0A449B8S9
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

114881:EXC37 RS03125
gene id: 114881:EXC37_RS03125
uniprot id: A0A449B9D6
names: Subcellular Location Annotation
messages: Cytoplasm

114881:EXC37 RS00765
gene id: 114881:EXC37_RS00765
uniprot id: A0A449B839
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

114881:EXC37 RS01825
gene id: 114881:EXC37_RS01825
uniprot id: A0A449B8M4
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

114881:EXC37 RS01020
gene id: 114881:EXC37_RS01020
uniprot id: A0A449B876
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL31 family.

114881:EXC37 RS00460
gene id: 114881:EXC37_RS00460
uniprot id: A0A449B7Y0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

114881:EXC37 RS03175
gene id: 114881:EXC37_RS03175
uniprot id: A0A449B9E4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

114881:EXC37 RS01000
gene id: 114881:EXC37_RS01000
uniprot id: A0A449B883
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

114881:EXC37 RS01555
gene id: 114881:EXC37_RS01555
uniprot id: A0A449B8I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

114881:EXC37 RS01840
gene id: 114881:EXC37_RS01840
uniprot id: A0A449B8N4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

114881:EXC37 RS02395
gene id: 114881:EXC37_RS02395
uniprot id: A0A449B8Y2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

114881:EXC37 RS00975
gene id: 114881:EXC37_RS00975
uniprot id: A0A449B868
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

114881:EXC37 RS02790
gene id: 114881:EXC37_RS02790
uniprot id: A0A449B957
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

114881:EXC37 RS03010
gene id: 114881:EXC37_RS03010
uniprot id: A0A449B994
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

114881:EXC37 RS02125
gene id: 114881:EXC37_RS02125
uniprot id: A0A449B8T7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

114881:EXC37 RS02290
gene id: 114881:EXC37_RS02290
uniprot id: A0A449B8X2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

114881:EXC37 RS01875
gene id: 114881:EXC37_RS01875
uniprot id: A0A449B8N5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

114881:EXC37 RS03180
gene id: 114881:EXC37_RS03180
uniprot id: A0A449B9E5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

114881:EXC37 RS03170
gene id: 114881:EXC37_RS03170
uniprot id: A0A449B9C4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

114881:EXC37 RS02095
gene id: 114881:EXC37_RS02095
uniprot id: A0A449B8U5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

114881:EXC37 RS02615
gene id: 114881:EXC37_RS02615
uniprot id: A0A449B929
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

114881:EXC37 RS01050
gene id: 114881:EXC37_RS01050
uniprot id: A0A449B893
names: Similarity
messages: Belongs to the MG185/MG260 family.

114881:EXC37 RS02835
gene id: 114881:EXC37_RS02835
uniprot id: A0A449B970
names: Similarity
messages: Belongs to the peptidase M17 family.

114881:EXC37 RS02370
gene id: 114881:EXC37_RS02370
uniprot id: A0A449B8Y6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

114881:EXC37 RS02120
gene id: 114881:EXC37_RS02120
uniprot id: A0A449B8T3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

114881:EXC37 RS00795
gene id: 114881:EXC37_RS00795
uniprot id: A0A449B827
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

114881:EXC37 RS00225
gene id: 114881:EXC37_RS00225
uniprot id: A0A449B7U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

114881:EXC37 RS00370
gene id: 114881:EXC37_RS00370
uniprot id: A0A449B7W2
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

114881:EXC37 RS02065
gene id: 114881:EXC37_RS02065
uniprot id: A0A449B8T1
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

114881:EXC37 RS03115
gene id: 114881:EXC37_RS03115
uniprot id: A0A449B9B7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm

114881:EXC37 RS01950
gene id: 114881:EXC37_RS01950
uniprot id: A0A449B8R8
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

114881:EXC37 RS01905
gene id: 114881:EXC37_RS01905
uniprot id: A0A449B8Q2
names: Subcellular Location Annotation
messages: Membrane

114881:EXC37 RS01645
gene id: 114881:EXC37_RS01645
uniprot id: A0A449B8K2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

114881:EXC37 RS01890
gene id: 114881:EXC37_RS01890
uniprot id: A0A449B8P3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

114881:EXC37 RS02380
gene id: 114881:EXC37_RS02380
uniprot id: A0A449B8Z2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

114881:EXC37 RS01860
gene id: 114881:EXC37_RS01860
uniprot id: A0A449B8Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

114881:EXC37 RS03130
gene id: 114881:EXC37_RS03130
uniprot id: A0A449B9D7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

114881:EXC37 RS00405
gene id: 114881:EXC37_RS00405
uniprot id: A0A449B7Y3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

114881:EXC37 RS00690
gene id: 114881:EXC37_RS00690
uniprot id: A0A449B818
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

114881:EXC37 RS02050
gene id: 114881:EXC37_RS02050
uniprot id: A0A449B8T0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

114881:EXC37 RS03160
gene id: 114881:EXC37_RS03160
uniprot id: A0A449B9B6
names: Subcellular Location Annotation
messages: Membrane

114881:EXC37 RS01025
gene id: 114881:EXC37_RS01025
uniprot id: A0A449B892
names: Similarity
messages: Belongs to the NusB family.

114881:EXC37 RS02690
gene id: 114881:EXC37_RS02690
uniprot id: A0A449B938
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

114881:EXC37 RS01515
gene id: 114881:EXC37_RS01515
uniprot id: A0A449B8G9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

114881:EXC37 RS02225
gene id: 114881:EXC37_RS02225
uniprot id: A0A449B8V7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.

114881:EXC37 RS02085
gene id: 114881:EXC37_RS02085
uniprot id: A0A449B8S6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

114881:EXC37 RS02245
gene id: 114881:EXC37_RS02245
uniprot id: A0A449B8Y0
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

114881:EXC37 RS01035
gene id: 114881:EXC37_RS01035
uniprot id: A0A449B877
names: Similarity
messages: Belongs to the ABC transporter superfamily.

114881:EXC37 RS00030
gene id: 114881:EXC37_RS00030
uniprot id: A0A449B7P7
names: Similarity
messages: Belongs to the lipase/esterase LIP3/BchO family.

114881:EXC37 RS01160
gene id: 114881:EXC37_RS01160
uniprot id: A0A449B8A7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

114881:EXC37 RS00060
gene id: 114881:EXC37_RS00060
uniprot id: A0A449B7P8
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

114881:EXC37 RS01135
gene id: 114881:EXC37_RS01135
uniprot id: A0A449B8A1
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

114881:EXC37 RS02710
gene id: 114881:EXC37_RS02710
uniprot id: A0A449B935
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

114881:EXC37 RS01600
gene id: 114881:EXC37_RS01600
uniprot id: A0A449B8J7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

114881:EXC37 RS01845
gene id: 114881:EXC37_RS01845
uniprot id: A0A449B8P8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

114881:EXC37 RS00360
gene id: 114881:EXC37_RS00360
uniprot id: A0A449B7V9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

114881:EXC37 RS01380
gene id: 114881:EXC37_RS01380
uniprot id: A0A449B8F1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

114881:EXC37 RS01750
gene id: 114881:EXC37_RS01750
uniprot id: A0A449B8M1
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

114881:EXC37 RS02275
gene id: 114881:EXC37_RS02275
uniprot id: A0A449B8W4
names: Similarity
messages: Belongs to the peptidase A8 family.

114881:EXC37 RS00480
gene id: 114881:EXC37_RS00480
uniprot id: A0A449B7Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

114881:EXC37 RS02150
gene id: 114881:EXC37_RS02150
uniprot id: A0A449B8V2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

114881:EXC37 RS02410
gene id: 114881:EXC37_RS02410
uniprot id: A0A449B912
names: Similarity
messages: Belongs to the peptidase M17 family.

114881:EXC37 RS00495
gene id: 114881:EXC37_RS00495
uniprot id: A0A449B7X6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

114881:EXC37 RS01370
gene id: 114881:EXC37_RS01370
uniprot id: A0A449B8F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

114881:EXC37 RS01140
gene id: 114881:EXC37_RS01140
uniprot id: A0A449B8C0
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

114881:EXC37 RS03095
gene id: 114881:EXC37_RS03095
uniprot id: A0A449B9C1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

114881:EXC37 RS00960
gene id: 114881:EXC37_RS00960
uniprot id: A0A449B858
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

114881:EXC37 RS00685
gene id: 114881:EXC37_RS00685
uniprot id: A0A449B804
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

114881:EXC37 RS03065
gene id: 114881:EXC37_RS03065
uniprot id: A0A449B9A5
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

114881:EXC37 RS02415
gene id: 114881:EXC37_RS02415
uniprot id: A0A449B8Z5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

114881:EXC37 RS01830
gene id: 114881:EXC37_RS01830
uniprot id: A0A449B8L9
names: Subcellular Location Annotation
messages: Membrane

114881:EXC37 RS01405
gene id: 114881:EXC37_RS01405
uniprot id: A0A449B8D3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

114881:EXC37 RS02695
gene id: 114881:EXC37_RS02695
uniprot id: A0A449B932
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

114881:EXC37 RS01430
gene id: 114881:EXC37_RS01430
uniprot id: A0A449B8G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.

114881:EXC37 RS01230
gene id: 114881:EXC37_RS01230
uniprot id: A0A449B8D9
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

114881:EXC37 RS00755
gene id: 114881:EXC37_RS00755
uniprot id: A0A449B824
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

114881:EXC37 RS01115
gene id: 114881:EXC37_RS01115
uniprot id: A0A449B887
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

114881:EXC37 RS02400
gene id: 114881:EXC37_RS02400
uniprot id: A0A449B8Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0154 family.
messages: Membrane

114881:EXC37 RS03165
gene id: 114881:EXC37_RS03165
uniprot id: A0A449B9C3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

114881:EXC37 RS00550
gene id: 114881:EXC37_RS00550
uniprot id: A0A449B7Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

114881:EXC37 RS02185
gene id: 114881:EXC37_RS02185
uniprot id: A0A449B8U6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

114881:EXC37 RS01045
gene id: 114881:EXC37_RS01045
uniprot id: A0A449B898
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

114881:EXC37 RS00740
gene id: 114881:EXC37_RS00740
uniprot id: A0A449B830
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

114881:EXC37 RS01345
gene id: 114881:EXC37_RS01345
uniprot id: A0A449B8C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

114881:EXC37 RS02060
gene id: 114881:EXC37_RS02060
uniprot id: A0A449B8U3
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

114881:EXC37 RS01480
gene id: 114881:EXC37_RS01480
uniprot id: A0A449B8H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

114881:EXC37 RS02990
gene id: 114881:EXC37_RS02990
uniprot id: A0A449B998
names: Similarity
messages: Belongs to the LacAB/RpiB family.

114881:EXC37 RS02995
gene id: 114881:EXC37_RS02995
uniprot id: A0A449B9A2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

114881:EXC37 RS00785
gene id: 114881:EXC37_RS00785
uniprot id: A0A449B849
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

114881:EXC37 RS01925
gene id: 114881:EXC37_RS01925
uniprot id: A0A449B8P5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

114881:EXC37 RS01945
gene id: 114881:EXC37_RS01945
uniprot id: A0A449B8Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

114881:EXC37 RS01630
gene id: 114881:EXC37_RS01630
uniprot id: A0A449B8K0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

114881:EXC37 RS00915
gene id: 114881:EXC37_RS00915
uniprot id: A0A449B850
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

114881:EXC37 RS03015
gene id: 114881:EXC37_RS03015
uniprot id: A0A449B996
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

114881:EXC37 RS02445
gene id: 114881:EXC37_RS02445
uniprot id: A0A449B8Z7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

114881:EXC37 RS02685
gene id: 114881:EXC37_RS02685
uniprot id: A0A449B940
names: Similarity
messages: Belongs to the RibF family.

114881:EXC37 RS00040
gene id: 114881:EXC37_RS00040
uniprot id: A0A449B7Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Cell membrane
messages: Membrane

114881:EXC37 RS01040
gene id: 114881:EXC37_RS01040
uniprot id: A0A449B8A0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

114881:EXC37 RS02285
gene id: 114881:EXC37_RS02285
uniprot id: A0A449B8V8
names: Similarity
messages: Belongs to the DprA/Smf family.

114881:EXC37 RS02075
gene id: 114881:EXC37_RS02075
uniprot id: A0A449B8S5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

114881:EXC37 RS02045
gene id: 114881:EXC37_RS02045
uniprot id: A0A449B8T5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

114881:EXC37 RS00735
gene id: 114881:EXC37_RS00735
uniprot id: A0A449B842
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

114881:EXC37 RS03085
gene id: 114881:EXC37_RS03085
uniprot id: A0A449B9C8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

114881:EXC37 RS01815
gene id: 114881:EXC37_RS01815
uniprot id: A0A449B8N2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

114881:EXC37 RS01635
gene id: 114881:EXC37_RS01635
uniprot id: A0A449B8L2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

114881:EXC37 RS00490
gene id: 114881:EXC37_RS00490
uniprot id: A0A449B7Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

114881:EXC37 RS00730
gene id: 114881:EXC37_RS00730
uniprot id: A0A449B833
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

114881:EXC37 RS02730
gene id: 114881:EXC37_RS02730
uniprot id: A0A449B956
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

114881:EXC37 RS02900
gene id: 114881:EXC37_RS02900
uniprot id: A0A449B972
names: Similarity
messages: Belongs to the protein kinase superfamily. BUD32 family.

114881:EXC37 RS02270
gene id: 114881:EXC37_RS02270
uniprot id: A0A449B8X0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

114881:EXC37 RS00935
gene id: 114881:EXC37_RS00935
uniprot id: A0A449B874
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

114881:EXC37 RS00940
gene id: 114881:EXC37_RS00940
uniprot id: A0A449B856
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

114881:EXC37 RS02800
gene id: 114881:EXC37_RS02800
uniprot id: A0A449B953
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

114881:EXC37 RS01855
gene id: 114881:EXC37_RS01855
uniprot id: A0A449B8P2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

114881:EXC37 RS02570
gene id: 114881:EXC37_RS02570
uniprot id: A0A449B927
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

114881:EXC37 RS02810
gene id: 114881:EXC37_RS02810
uniprot id: A0A449B958
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

114881:EXC37 RS01640
gene id: 114881:EXC37_RS01640
uniprot id: A0A449B8J6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

114881:EXC37 RS01870
gene id: 114881:EXC37_RS01870
uniprot id: A0A449B8M7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

114881:EXC37 RS00945
gene id: 114881:EXC37_RS00945
uniprot id: A0A449B875
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.