1144748:KS2013 RS10655
gene id: 1144748:KS2013_RS10655
uniprot id: A0A1B3BDD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1144748:KS2013 RS10725
gene id: 1144748:KS2013_RS10725
uniprot id: A0A1B3BDH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1144748:KS2013 RS01120
gene id: 1144748:KS2013_RS01120
uniprot id: A0A1B3B832
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1144748:KS2013 RS05210
gene id: 1144748:KS2013_RS05210
uniprot id: A0A1B3BAC0
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1144748:KS2013 RS07880
gene id: 1144748:KS2013_RS07880
uniprot id: A0A1B3BBU8
names: Subcellular Location Annotation
messages: Membrane

1144748:KS2013 RS01260
gene id: 1144748:KS2013_RS01260
uniprot id: A0A1B3B852
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1144748:KS2013 RS04165
gene id: 1144748:KS2013_RS04165
uniprot id: A0A1B3B9R6
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

1144748:KS2013 RS10185
gene id: 1144748:KS2013_RS10185
uniprot id: A0A1B3BD19
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

1144748:KS2013 RS05135
gene id: 1144748:KS2013_RS05135
uniprot id: A0A1B3BA97
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

1144748:KS2013 RS06680
gene id: 1144748:KS2013_RS06680
uniprot id: A0A1B3BB62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1144748:KS2013 RS08510
gene id: 1144748:KS2013_RS08510
uniprot id: A0A1B3BC62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1144748:KS2013 RS02190
gene id: 1144748:KS2013_RS02190
uniprot id: A0A1B3B8P4
names: Similarity
messages: Belongs to the UPF0111 family.

1144748:KS2013 RS07745
gene id: 1144748:KS2013_RS07745
uniprot id: A0A1B3BBS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1144748:KS2013 RS00375
gene id: 1144748:KS2013_RS00375
uniprot id: A0A1B3B7P3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

1144748:KS2013 RS11625
gene id: 1144748:KS2013_RS11625
uniprot id: A0A1B3BDV4
names: Similarity
messages: Belongs to the Lgt family.

1144748:KS2013 RS00070
gene id: 1144748:KS2013_RS00070
uniprot id: A0A1B3B7H8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

1144748:KS2013 RS00770
gene id: 1144748:KS2013_RS00770
uniprot id: A0A1B3B7X3
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1144748:KS2013 RS04795
gene id: 1144748:KS2013_RS04795
uniprot id: A0A1B3BA38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1144748:KS2013 RS11045
gene id: 1144748:KS2013_RS11045
uniprot id: A0A1B3BDM0
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

1144748:KS2013 RS02145
gene id: 1144748:KS2013_RS02145
uniprot id: A0A1B3B8M1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1144748:KS2013 RS06700
gene id: 1144748:KS2013_RS06700
uniprot id: A0A1B3BB95
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

1144748:KS2013 RS02035
gene id: 1144748:KS2013_RS02035
uniprot id: A0A1B3B8L1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1144748:KS2013 RS11550
gene id: 1144748:KS2013_RS11550
uniprot id: A0A1B3BDW6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

1144748:KS2013 RS07970
gene id: 1144748:KS2013_RS07970
uniprot id: A0A1B3BBW6
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1144748:KS2013 RS11560
gene id: 1144748:KS2013_RS11560
uniprot id: A0A1B3BDV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1144748:KS2013 RS11425
gene id: 1144748:KS2013_RS11425
uniprot id: A0A1B3BE07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1144748:KS2013 RS04130
gene id: 1144748:KS2013_RS04130
uniprot id: A0A1B3B9S0
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1144748:KS2013 RS07360
gene id: 1144748:KS2013_RS07360
uniprot id: A0A1B3BBJ8
names: Subcellular Location Annotation
messages: Membrane

1144748:KS2013 RS06510
gene id: 1144748:KS2013_RS06510
uniprot id: A0A1B3BB24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

1144748:KS2013 RS05835
gene id: 1144748:KS2013_RS05835
uniprot id: A0A1B3BAS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1144748:KS2013 RS11430
gene id: 1144748:KS2013_RS11430
uniprot id: A0A1B3BDR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

1144748:KS2013 RS06640
gene id: 1144748:KS2013_RS06640
uniprot id: A0A1B3BB55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1144748:KS2013 RS08850
gene id: 1144748:KS2013_RS08850
uniprot id: A0A1B3BCE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1144748:KS2013 RS08410
gene id: 1144748:KS2013_RS08410
uniprot id: A0A1B3BC97
names: Similarity
messages: Belongs to the GST superfamily.

1144748:KS2013 RS04280
gene id: 1144748:KS2013_RS04280
uniprot id: A0A1B3B9T9
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

1144748:KS2013 RS01125
gene id: 1144748:KS2013_RS01125
uniprot id: A0A1B3B827
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1144748:KS2013 RS03335
gene id: 1144748:KS2013_RS03335
uniprot id: A0A1B3B9E4
names: Subcellular Location Annotation
messages: Membrane

1144748:KS2013 RS07420
gene id: 1144748:KS2013_RS07420
uniprot id: A0A1B3BBL0
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1144748:KS2013 RS10065
gene id: 1144748:KS2013_RS10065
uniprot id: A0A1B3BD57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1144748:KS2013 RS05395
gene id: 1144748:KS2013_RS05395
uniprot id: A0A1B3BAG8
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144748:KS2013 RS04115
gene id: 1144748:KS2013_RS04115
uniprot id: A0A1B3B9R1
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1144748:KS2013 RS09885
gene id: 1144748:KS2013_RS09885
uniprot id: A0A1B3BD28
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1144748:KS2013 RS03110
gene id: 1144748:KS2013_RS03110
uniprot id: A0A1B3B989
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1144748:KS2013 RS08360
gene id: 1144748:KS2013_RS08360
uniprot id: A0A1B3BC81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1144748:KS2013 RS01715
gene id: 1144748:KS2013_RS01715
uniprot id: A0A1B3B8G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1144748:KS2013 RS11600
gene id: 1144748:KS2013_RS11600
uniprot id: A0A1B3BDX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1144748:KS2013 RS05655
gene id: 1144748:KS2013_RS05655
uniprot id: A0A1B3BAM2
names: Similarity
messages: Belongs to the pirin family.

1144748:KS2013 RS00335
gene id: 1144748:KS2013_RS00335
uniprot id: A0A1B3B7M9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

1144748:KS2013 RS07855
gene id: 1144748:KS2013_RS07855
uniprot id: A0A1B3BBV6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1144748:KS2013 RS02515
gene id: 1144748:KS2013_RS02515
uniprot id: A0A1B3B8U9
names: Similarity
messages: Belongs to the nitroreductase family. HadB/RutE subfamily.

1144748:KS2013 RS07705
gene id: 1144748:KS2013_RS07705
uniprot id: A0A1B3BBR9
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1144748:KS2013 RS06695
gene id: 1144748:KS2013_RS06695
uniprot id: A0A1B3BBA1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1144748:KS2013 RS09420
gene id: 1144748:KS2013_RS09420
uniprot id: A0A1B3BCT4
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

1144748:KS2013 RS04800
gene id: 1144748:KS2013_RS04800
uniprot id: A0A1B3BA31
names: Similarity
messages: Belongs to the peptidase M16 family.

1144748:KS2013 RS06515
gene id: 1144748:KS2013_RS06515
uniprot id: A0A1B3BB26
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1144748:KS2013 RS11790
gene id: 1144748:KS2013_RS11790
uniprot id: A0A1B3BE13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1144748:KS2013 RS04910
gene id: 1144748:KS2013_RS04910
uniprot id: A0A1B3BAA9
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1144748:KS2013 RS04095
gene id: 1144748:KS2013_RS04095
uniprot id: A0A1B3B9X7
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1144748:KS2013 RS01460
gene id: 1144748:KS2013_RS01460
uniprot id: A0A1B3B8C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1144748:KS2013 RS09980
gene id: 1144748:KS2013_RS09980
uniprot id: A0A1B3BD55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1144748:KS2013 RS11215
gene id: 1144748:KS2013_RS11215
uniprot id: A0A1B3BDL5
names: Similarity
messages: Belongs to the DEAD box helicase family.

1144748:KS2013 RS10660
gene id: 1144748:KS2013_RS10660
uniprot id: A0A1B3BDB8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1144748:KS2013 RS06755
gene id: 1144748:KS2013_RS06755
uniprot id: A0A1B3BBA4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144748:KS2013 RS01245
gene id: 1144748:KS2013_RS01245
uniprot id: A0A1B3B857
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1144748:KS2013 RS06520
gene id: 1144748:KS2013_RS06520
uniprot id: A0A1B3BB27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1144748:KS2013 RS09875
gene id: 1144748:KS2013_RS09875
uniprot id: A0A1B3BD13
names: Subcellular Location Annotation
messages: Membrane

1144748:KS2013 RS00655
gene id: 1144748:KS2013_RS00655
uniprot id: A0A1B3B7U4
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

1144748:KS2013 RS07830
gene id: 1144748:KS2013_RS07830
uniprot id: A0A1B3BBT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1144748:KS2013 RS04915
gene id: 1144748:KS2013_RS04915
uniprot id: A0A1B3BA82
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1144748:KS2013 RS00950
gene id: 1144748:KS2013_RS00950
uniprot id: A0A1B3B800
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1144748:KS2013 RS05715
gene id: 1144748:KS2013_RS05715
uniprot id: A0A1B3BAM7
names: Similarity
messages: Belongs to the CopC family.

1144748:KS2013 RS07190
gene id: 1144748:KS2013_RS07190
uniprot id: A0A1B3BBG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiU subfamily.
messages: Forms an heterodimer with UbiV.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiV, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

1144748:KS2013 RS02630
gene id: 1144748:KS2013_RS02630
uniprot id: A0A1B3B8Y5
names: Subcellular Location Annotation
messages: Cell inner membrane

1144748:KS2013 RS08300
gene id: 1144748:KS2013_RS08300
uniprot id: A0A1B3BC20
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1144748:KS2013 RS11505
gene id: 1144748:KS2013_RS11505
uniprot id: A0A1B3BDT8
names: Subunit
messages: Monomer.

1144748:KS2013 RS08000
gene id: 1144748:KS2013_RS08000
uniprot id: A0A1B3BBX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1144748:KS2013 RS03390
gene id: 1144748:KS2013_RS03390
uniprot id: A0A1B3B9C4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1144748:KS2013 RS00480
gene id: 1144748:KS2013_RS00480
uniprot id: A0A1B3B7R6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

1144748:KS2013 RS09835
gene id: 1144748:KS2013_RS09835
uniprot id: A0A1B3BD52
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

1144748:KS2013 RS08065
gene id: 1144748:KS2013_RS08065
uniprot id: A0A1B3BBX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1144748:KS2013 RS05465
gene id: 1144748:KS2013_RS05465
uniprot id: A0A1B3BAH3
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

1144748:KS2013 RS08075
gene id: 1144748:KS2013_RS08075
uniprot id: A0A1B3BBY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1144748:KS2013 RS06495
gene id: 1144748:KS2013_RS06495
uniprot id: A0A1B3BB48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

1144748:KS2013 RS01955
gene id: 1144748:KS2013_RS01955
uniprot id: A0A1B3B8J5
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

1144748:KS2013 RS06275
gene id: 1144748:KS2013_RS06275
uniprot id: A0A1B3BAY3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144748:KS2013 RS11435
gene id: 1144748:KS2013_RS11435
uniprot id: A0A1B3BE38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

1144748:KS2013 RS11260
gene id: 1144748:KS2013_RS11260
uniprot id: A0A1B3BDT9
names: Similarity
messages: Belongs to the Dps family.

1144748:KS2013 RS02025
gene id: 1144748:KS2013_RS02025
uniprot id: A0A1B3B8N2
names: Subcellular Location Annotation
messages: Membrane

1144748:KS2013 RS07025
gene id: 1144748:KS2013_RS07025
uniprot id: A0A1B3BBC7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1144748:KS2013 RS02925
gene id: 1144748:KS2013_RS02925
uniprot id: A0A1B3B959
names: Subcellular Location Annotation
messages: Membrane

1144748:KS2013 RS05965
gene id: 1144748:KS2013_RS05965
uniprot id: A0A1B3BAS5
names: Subcellular Location Annotation
messages: Membrane

1144748:KS2013 RS01565
gene id: 1144748:KS2013_RS01565
uniprot id: A0A1B3B8E7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144748:KS2013 RS03385
gene id: 1144748:KS2013_RS03385
uniprot id: A0A1B3B9F4
names: Subcellular Location Annotation
messages: Membrane

1144748:KS2013 RS02185
gene id: 1144748:KS2013_RS02185
uniprot id: A0A1B3B8N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1144748:KS2013 RS10555
gene id: 1144748:KS2013_RS10555
uniprot id: A0A1B3BD98
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1144748:KS2013 RS06540
gene id: 1144748:KS2013_RS06540
uniprot id: A0A1B3BB32
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1144748:KS2013 RS11665
gene id: 1144748:KS2013_RS11665
uniprot id: A0A1B3BDV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

1144748:KS2013 RS07120
gene id: 1144748:KS2013_RS07120
uniprot id: A0A1B3BBH1
names: Subcellular Location Annotation
messages: Membrane

1144748:KS2013 RS00505
gene id: 1144748:KS2013_RS00505
uniprot id: A0A1B3B7R9
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

1144748:KS2013 RS00650
gene id: 1144748:KS2013_RS00650
uniprot id: A0A1B3B7U6
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1144748:KS2013 RS08775
gene id: 1144748:KS2013_RS08775
uniprot id: A0A1B3BCI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.

1144748:KS2013 RS04195
gene id: 1144748:KS2013_RS04195
uniprot id: A0A1B3B9U5
names: Similarity
messages: Belongs to the DEAD box helicase family.

1144748:KS2013 RS01470
gene id: 1144748:KS2013_RS01470
uniprot id: A0A1B3B892
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

1144748:KS2013 RS02900
gene id: 1144748:KS2013_RS02900
uniprot id: A0A1B3B947
names: Subunit
messages: Monomer.

1144748:KS2013 RS05265
gene id: 1144748:KS2013_RS05265
uniprot id: A0A1B3BAC4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

1144748:KS2013 RS02390
gene id: 1144748:KS2013_RS02390
uniprot id: A0A1B3B8R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1144748:KS2013 RS09700
gene id: 1144748:KS2013_RS09700
uniprot id: A0A1B3BCW9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

1144748:KS2013 RS09920
gene id: 1144748:KS2013_RS09920
uniprot id: A0A1B3BCX9
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1144748:KS2013 RS02580
gene id: 1144748:KS2013_RS02580
uniprot id: A0A1B3B8X4
names: Similarity
messages: Belongs to the asparagine synthetase family.

1144748:KS2013 RS06770
gene id: 1144748:KS2013_RS06770
uniprot id: A0A1B3BB82
names: Cofactor
names: Function
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.

1144748:KS2013 RS05900
gene id: 1144748:KS2013_RS05900
uniprot id: A0A1B3BAS4
names: Similarity
messages: Belongs to the GSP E family.

1144748:KS2013 RS01090
gene id: 1144748:KS2013_RS01090
uniprot id: A0A1B3B834
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1144748:KS2013 RS01615
gene id: 1144748:KS2013_RS01615
uniprot id: A0A1B3B8F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1144748:KS2013 RS07475
gene id: 1144748:KS2013_RS07475
uniprot id: A0A1B3BBP9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

1144748:KS2013 RS07985
gene id: 1144748:KS2013_RS07985
uniprot id: A0A1B3BBW7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1144748:KS2013 RS00135
gene id: 1144748:KS2013_RS00135
uniprot id: A0A1B3B7J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Slam family.
messages: Cell outer membrane
messages: Membrane

1144748:KS2013 RS05280
gene id: 1144748:KS2013_RS05280
uniprot id: A0A1B3BAD3
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1144748:KS2013 RS09810
gene id: 1144748:KS2013_RS09810
uniprot id: A0A1B3BCX7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1144748:KS2013 RS10540
gene id: 1144748:KS2013_RS10540
uniprot id: A0A1B3BD87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1144748:KS2013 RS04945
gene id: 1144748:KS2013_RS04945
uniprot id: A0A1B3BA64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

1144748:KS2013 RS10635
gene id: 1144748:KS2013_RS10635
uniprot id: A0A1B3BDN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1144748:KS2013 RS08875
gene id: 1144748:KS2013_RS08875
uniprot id: A0A1B3BCJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1144748:KS2013 RS01590
gene id: 1144748:KS2013_RS01590
uniprot id: A0A1B3B8G4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1144748:KS2013 RS08435
gene id: 1144748:KS2013_RS08435
uniprot id: A0A1B3BC59
names: Similarity
messages: Belongs to the YjdM family.

1144748:KS2013 RS09895
gene id: 1144748:KS2013_RS09895
uniprot id: A0A1B3BD00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1144748:KS2013 RS07665
gene id: 1144748:KS2013_RS07665
uniprot id: A0A1B3BBQ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1144748:KS2013 RS08610
gene id: 1144748:KS2013_RS08610
uniprot id: A0A1B3BC89
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1144748:KS2013 RS09860
gene id: 1144748:KS2013_RS09860
uniprot id: A0A1B3BCY0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144748:KS2013 RS11015
gene id: 1144748:KS2013_RS11015
uniprot id: A0A1B3BDH5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1144748:KS2013 RS10980
gene id: 1144748:KS2013_RS10980
uniprot id: A0A1B3BDV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1144748:KS2013 RS03625
gene id: 1144748:KS2013_RS03625
uniprot id: A0A1B3B9K7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1144748:KS2013 RS09330
gene id: 1144748:KS2013_RS09330
uniprot id: A0A1B3BCR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1144748:KS2013 RS00750
gene id: 1144748:KS2013_RS00750
uniprot id: A0A1B3B7W0
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

1144748:KS2013 RS10025
gene id: 1144748:KS2013_RS10025
uniprot id: A0A1B3BDD6
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1144748:KS2013 RS02100
gene id: 1144748:KS2013_RS02100
uniprot id: A0A1B3B8N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1144748:KS2013 RS08030
gene id: 1144748:KS2013_RS08030
uniprot id: A0A1B3BC05
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

1144748:KS2013 RS05970
gene id: 1144748:KS2013_RS05970
uniprot id: A0A1B3BAU1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1144748:KS2013 RS00920
gene id: 1144748:KS2013_RS00920
uniprot id: A0A1B3B7Z6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144748:KS2013 RS07675
gene id: 1144748:KS2013_RS07675
uniprot id: A0A1B3BBT5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144748:KS2013 RS02425
gene id: 1144748:KS2013_RS02425
uniprot id: A0A1B3B8V7
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

1144748:KS2013 RS04320
gene id: 1144748:KS2013_RS04320
uniprot id: A0A1B3B9U6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1144748:KS2013 RS10005
gene id: 1144748:KS2013_RS10005
uniprot id: A0A1B3BD60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1144748:KS2013 RS08005
gene id: 1144748:KS2013_RS08005
uniprot id: A0A1B3BBX1
names: Similarity
messages: Belongs to the YfgM family.

1144748:KS2013 RS03235
gene id: 1144748:KS2013_RS03235
uniprot id: A0A1B3B987
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1144748:KS2013 RS00585
gene id: 1144748:KS2013_RS00585
uniprot id: A0A1B3B7T6
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1144748:KS2013 RS10050
gene id: 1144748:KS2013_RS10050
uniprot id: A0A1B3BD21
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1144748:KS2013 RS01045
gene id: 1144748:KS2013_RS01045
uniprot id: A0A1B3B830
names: Similarity
messages: Belongs to the glutamate synthase family.

1144748:KS2013 RS08085
gene id: 1144748:KS2013_RS08085
uniprot id: A0A1B3BBY4
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1144748:KS2013 RS10905
gene id: 1144748:KS2013_RS10905
uniprot id: A0A1B3BDH4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1144748:KS2013 RS07430
gene id: 1144748:KS2013_RS07430
uniprot id: A0A1B3BBK8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1144748:KS2013 RS01865
gene id: 1144748:KS2013_RS01865
uniprot id: A0A1B3B8J7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1144748:KS2013 RS07780
gene id: 1144748:KS2013_RS07780
uniprot id: A0A1B3BBT0
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

1144748:KS2013 RS09910
gene id: 1144748:KS2013_RS09910
uniprot id: A0A1B3BCW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1144748:KS2013 RS09470
gene id: 1144748:KS2013_RS09470
uniprot id: A0A1B3BCU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1144748:KS2013 RS00060
gene id: 1144748:KS2013_RS00060
uniprot id: A0A1B3B7H7
names: Similarity
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

1144748:KS2013 RS07020
gene id: 1144748:KS2013_RS07020
uniprot id: A0A1B3BBE8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1144748:KS2013 RS09180
gene id: 1144748:KS2013_RS09180
uniprot id: A0A1B3BCI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1144748:KS2013 RS00695
gene id: 1144748:KS2013_RS00695
uniprot id: A0A1B3B7V2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1144748:KS2013 RS03085
gene id: 1144748:KS2013_RS03085
uniprot id: A0A1B3B985
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1144748:KS2013 RS06360
gene id: 1144748:KS2013_RS06360
uniprot id: A0A1B3BB03
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144748:KS2013 RS00415
gene id: 1144748:KS2013_RS00415
uniprot id: A0A1B3B7R1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Cell membrane
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

1144748:KS2013 RS04360
gene id: 1144748:KS2013_RS04360
uniprot id: A0A1B3BA00
names: Similarity
messages: Belongs to the PrpF family.

1144748:KS2013 RS00835
gene id: 1144748:KS2013_RS00835
uniprot id: A0A1B3B7Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MutH family.
messages: Cytoplasm
messages: Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair.

1144748:KS2013 RS08145
gene id: 1144748:KS2013_RS08145
uniprot id: A0A1B3BBZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1144748:KS2013 RS06905
gene id: 1144748:KS2013_RS06905
uniprot id: A0A1B3BBA5
names: Similarity
messages: Belongs to the WrbA family.

1144748:KS2013 RS05800
gene id: 1144748:KS2013_RS05800
uniprot id: A0A1B3BAP6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1144748:KS2013 RS07235
gene id: 1144748:KS2013_RS07235
uniprot id: A0A1B3BBG8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1144748:KS2013 RS07720
gene id: 1144748:KS2013_RS07720
uniprot id: A0A1B3BBR8
names: Similarity
messages: Belongs to the P(II) protein family.

1144748:KS2013 RS08895
gene id: 1144748:KS2013_RS08895
uniprot id: A0A1B3BCD1
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.

1144748:KS2013 RS10515
gene id: 1144748:KS2013_RS10515
uniprot id: A0A1B3BD67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1144748:KS2013 RS11740
gene id: 1144748:KS2013_RS11740
uniprot id: A0A1B3BDX3
names: Subcellular Location Annotation
messages: Membrane

1144748:KS2013 RS03865
gene id: 1144748:KS2013_RS03865
uniprot id: A0A1B3B9M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1144748:KS2013 RS03320
gene id: 1144748:KS2013_RS03320
uniprot id: A0A1B3B9C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm

1144748:KS2013 RS06365
gene id: 1144748:KS2013_RS06365
uniprot id: A0A1B3BB30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell membrane
messages: Cytoplasm

1144748:KS2013 RS10055
gene id: 1144748:KS2013_RS10055
uniprot id: A0A1B3BD69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1144748:KS2013 RS04325
gene id: 1144748:KS2013_RS04325
uniprot id: A0A1B3B9V3
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1144748:KS2013 RS06130
gene id: 1144748:KS2013_RS06130
uniprot id: A0A1B3BAW5
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.

1144748:KS2013 RS02030
gene id: 1144748:KS2013_RS02030
uniprot id: A0A1B3B8K3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

1144748:KS2013 RS10410
gene id: 1144748:KS2013_RS10410
uniprot id: A0A1B3BDC7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1144748:KS2013 RS03030
gene id: 1144748:KS2013_RS03030
uniprot id: A0A1B3B964
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144748:KS2013 RS05815
gene id: 1144748:KS2013_RS05815
uniprot id: A0A1B3BAP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1144748:KS2013 RS09580
gene id: 1144748:KS2013_RS09580
uniprot id: A0A1B3BCV8
names: Similarity
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

1144748:KS2013 RS08885
gene id: 1144748:KS2013_RS08885
uniprot id: A0A1B3BCD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1144748:KS2013 RS06810
gene id: 1144748:KS2013_RS06810
uniprot id: A0A1B3BBB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1144748:KS2013 RS00700
gene id: 1144748:KS2013_RS00700
uniprot id: A0A1B3B7V6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

1144748:KS2013 RS11730
gene id: 1144748:KS2013_RS11730
uniprot id: A0A1B3BEA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1144748:KS2013 RS04330
gene id: 1144748:KS2013_RS04330
uniprot id: A0A1B3B9V0
names: Similarity
messages: Belongs to the Nudix hydrolase family. PCD1 subfamily.

1144748:KS2013 RS10995
gene id: 1144748:KS2013_RS10995
uniprot id: A0A1B3BDL2
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1144748:KS2013 RS04350
gene id: 1144748:KS2013_RS04350
uniprot id: A0A1B3BA23
names: Similarity
messages: Belongs to the citrate synthase family.

1144748:KS2013 RS07595
gene id: 1144748:KS2013_RS07595
uniprot id: A0A1B3BBP0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1144748:KS2013 RS07480
gene id: 1144748:KS2013_RS07480
uniprot id: A0A1B3BBL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

1144748:KS2013 RS10965
gene id: 1144748:KS2013_RS10965
uniprot id: A0A1B3BDG4
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1144748:KS2013 RS04725
gene id: 1144748:KS2013_RS04725
uniprot id: A0A1B3BA61
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1144748:KS2013 RS05480
gene id: 1144748:KS2013_RS05480
uniprot id: A0A1B3BAI2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1144748:KS2013 RS08365
gene id: 1144748:KS2013_RS08365
uniprot id: A0A1B3BC39
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1144748:KS2013 RS05790
gene id: 1144748:KS2013_RS05790
uniprot id: A0A1B3BAQ5
names: Subcellular Location Annotation
messages: Membrane

1144748:KS2013 RS08175
gene id: 1144748:KS2013_RS08175
uniprot id: A0A1B3BC06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1144748:KS2013 RS06200
gene id: 1144748:KS2013_RS06200
uniprot id: A0A1B3BAX4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family. L-methionine gamma-lyase subfamily.

1144748:KS2013 RS09780
gene id: 1144748:KS2013_RS09780
uniprot id: A0A1B3BCU2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1144748:KS2013 RS10945
gene id: 1144748:KS2013_RS10945
uniprot id: A0A1B3BDK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1144748:KS2013 RS01935
gene id: 1144748:KS2013_RS01935
uniprot id: A0A1B3B8H7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

1144748:KS2013 RS09815
gene id: 1144748:KS2013_RS09815
uniprot id: A0A1B3BD27
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1144748:KS2013 RS09005
gene id: 1144748:KS2013_RS09005
uniprot id: A0A1B3BCH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AFG1 ATPase family. ZapE subfamily.
messages: Cytoplasm
messages: Interacts with FtsZ.
messages: Reduces the stability of FtsZ polymers in the presence of ATP.

1144748:KS2013 RS10260
gene id: 1144748:KS2013_RS10260
uniprot id: A0A1B3BD93
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1144748:KS2013 RS01670
gene id: 1144748:KS2013_RS01670
uniprot id: A0A1B3B8H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1144748:KS2013 RS08425
gene id: 1144748:KS2013_RS08425
uniprot id: A0A1B3BC47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm

1144748:KS2013 RS08420
gene id: 1144748:KS2013_RS08420
uniprot id: A0A1B3BC83
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144748:KS2013 RS02975
gene id: 1144748:KS2013_RS02975
uniprot id: A0A1B3B961
names: Similarity
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

1144748:KS2013 RS00965
gene id: 1144748:KS2013_RS00965
uniprot id: A0A1B3B805
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabB family.
messages: Cell membrane
messages: Forms a complex with DabA.
messages: Membrane
messages: Part of an energy-coupled inorganic carbon pump.

1144748:KS2013 RS08660
gene id: 1144748:KS2013_RS08660
uniprot id: A0A1B3BC93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

1144748:KS2013 RS06880
gene id: 1144748:KS2013_RS06880
uniprot id: A0A1B3BB93
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48 family. BepA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
messages: Periplasm

1144748:KS2013 RS09475
gene id: 1144748:KS2013_RS09475
uniprot id: A0A1B3BCP2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1144748:KS2013 RS08335
gene id: 1144748:KS2013_RS08335
uniprot id: A0A1B3BC42
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144748:KS2013 RS07205
gene id: 1144748:KS2013_RS07205
uniprot id: A0A1B3BBG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1144748:KS2013 RS09310
gene id: 1144748:KS2013_RS09310
uniprot id: A0A1B3BCL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

1144748:KS2013 RS02805
gene id: 1144748:KS2013_RS02805
uniprot id: A0A1B3B957
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

1144748:KS2013 RS04960
gene id: 1144748:KS2013_RS04960
uniprot id: A0A1B3BAC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

1144748:KS2013 RS07505
gene id: 1144748:KS2013_RS07505
uniprot id: A0A1B3BBN1
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1144748:KS2013 RS10325
gene id: 1144748:KS2013_RS10325
uniprot id: A0A1B3BD56
names: Function
names: Similarity
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.

1144748:KS2013 RS07840
gene id: 1144748:KS2013_RS07840
uniprot id: A0A1B3BBT1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1144748:KS2013 RS09830
gene id: 1144748:KS2013_RS09830
uniprot id: A0A1B3BCV6
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1144748:KS2013 RS08465
gene id: 1144748:KS2013_RS08465
uniprot id: A0A1B3BC57
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

1144748:KS2013 RS07730
gene id: 1144748:KS2013_RS07730
uniprot id: A0A1B3BBS6
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1144748:KS2013 RS09415
gene id: 1144748:KS2013_RS09415
uniprot id: A0A1B3BCQ5
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1144748:KS2013 RS06660
gene id: 1144748:KS2013_RS06660
uniprot id: A0A1B3BB51
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1144748:KS2013 RS00640
gene id: 1144748:KS2013_RS00640
uniprot id: A0A1B3B7U1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1144748:KS2013 RS00380
gene id: 1144748:KS2013_RS00380
uniprot id: A0A1B3B7P1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

1144748:KS2013 RS04250
gene id: 1144748:KS2013_RS04250
uniprot id: A0A1B3BA06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1144748:KS2013 RS08985
gene id: 1144748:KS2013_RS08985
uniprot id: A0A1B3BCJ9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1144748:KS2013 RS00860
gene id: 1144748:KS2013_RS00860
uniprot id: A0A1B3B7Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1144748:KS2013 RS03420
gene id: 1144748:KS2013_RS03420
uniprot id: A0A1B3B9E7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1144748:KS2013 RS05085
gene id: 1144748:KS2013_RS05085
uniprot id: A0A1B3BA88
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1144748:KS2013 RS01550
gene id: 1144748:KS2013_RS01550
uniprot id: A0A1B3B8B2
names: Subcellular Location Annotation
messages: Membrane

1144748:KS2013 RS11865
gene id: 1144748:KS2013_RS11865
uniprot id: A0A1B3BD46
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1144748:KS2013 RS11715
gene id: 1144748:KS2013_RS11715
uniprot id: A0A1B3BDW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1144748:KS2013 RS07660
gene id: 1144748:KS2013_RS07660
uniprot id: A0A1B3BBQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1144748:KS2013 RS03355
gene id: 1144748:KS2013_RS03355
uniprot id: A0A1B3B9C2
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family. AstD subfamily.
messages: Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.

1144748:KS2013 RS08955
gene id: 1144748:KS2013_RS08955
uniprot id: A0A1B3BCG5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

1144748:KS2013 RS01040
gene id: 1144748:KS2013_RS01040
uniprot id: A0A1B3B854
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1144748:KS2013 RS09515
gene id: 1144748:KS2013_RS09515
uniprot id: A0A1B3BCS0
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

1144748:KS2013 RS06025
gene id: 1144748:KS2013_RS06025
uniprot id: A0A1B3BAT6
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1144748:KS2013 RS09295
gene id: 1144748:KS2013_RS09295
uniprot id: A0A1B3BCS3
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144748:KS2013 RS10505
gene id: 1144748:KS2013_RS10505
uniprot id: A0A1B3BD92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1144748:KS2013 RS08520
gene id: 1144748:KS2013_RS08520
uniprot id: A0A1B3BC70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1144748:KS2013 RS00940
gene id: 1144748:KS2013_RS00940
uniprot id: A0A1B3B837
names: Similarity
messages: Belongs to the RutC family.

1144748:KS2013 RS02080
gene id: 1144748:KS2013_RS02080
uniprot id: A0A1B3B8P1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1144748:KS2013 RS11785
gene id: 1144748:KS2013_RS11785
uniprot id: A0A1B3BE40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1144748:KS2013 RS09615
gene id: 1144748:KS2013_RS09615
uniprot id: A0A1B3BCT8
names: Similarity
messages: Belongs to the elongation factor P family.

1144748:KS2013 RS10390
gene id: 1144748:KS2013_RS10390
uniprot id: A0A1B3BD63
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1144748:KS2013 RS09605
gene id: 1144748:KS2013_RS09605
uniprot id: A0A1B3BCR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. AOTCase family.
messages: Catalyzes the transfer of the carbamoyl group from carbamoyl phosphate to the delta-amino group of N(2)-acetyl-L-ornithine to produce N(2)-acetyl-L-citrulline. This is a step in an alternative arginine biosynthesis pathway.
messages: Cytoplasm
messages: Homotrimer.

1144748:KS2013 RS00915
gene id: 1144748:KS2013_RS00915
uniprot id: A0A1B3B7Z5
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1144748:KS2013 RS11525
gene id: 1144748:KS2013_RS11525
uniprot id: A0A1B3BE26
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1144748:KS2013 RS05285
gene id: 1144748:KS2013_RS05285
uniprot id: A0A1B3BAJ2
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

1144748:KS2013 RS03545
gene id: 1144748:KS2013_RS03545
uniprot id: A0A1B3B9G6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

1144748:KS2013 RS07795
gene id: 1144748:KS2013_RS07795
uniprot id: A0A1B3BBT8
names: Caution
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144748:KS2013 RS08575
gene id: 1144748:KS2013_RS08575
uniprot id: A0A1B3BCE7
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

1144748:KS2013 RS09805
gene id: 1144748:KS2013_RS09805
uniprot id: A0A1B3BCV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1144748:KS2013 RS08035
gene id: 1144748:KS2013_RS08035
uniprot id: A0A1B3BBX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1144748:KS2013 RS02150
gene id: 1144748:KS2013_RS02150
uniprot id: A0A1B3B8P8
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

1144748:KS2013 RS06800
gene id: 1144748:KS2013_RS06800
uniprot id: A0A1B3BB91
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MetJ family.
messages: Cytoplasm
messages: Homodimer.

1144748:KS2013 RS04755
gene id: 1144748:KS2013_RS04755
uniprot id: A0A1B3BA37
names: Similarity
messages: Belongs to the citrate synthase family.

1144748:KS2013 RS10615
gene id: 1144748:KS2013_RS10615
uniprot id: A0A1B3BD89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1144748:KS2013 RS08560
gene id: 1144748:KS2013_RS08560
uniprot id: A0A1B3BC85
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1144748:KS2013 RS03515
gene id: 1144748:KS2013_RS03515
uniprot id: A0A1B3B9E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1144748:KS2013 RS10535
gene id: 1144748:KS2013_RS10535
uniprot id: A0A1B3BDE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

1144748:KS2013 RS00390
gene id: 1144748:KS2013_RS00390
uniprot id: A0A1B3B7P5
names: Subcellular Location Annotation
messages: Membrane

1144748:KS2013 RS10285
gene id: 1144748:KS2013_RS10285
uniprot id: A0A1B3BD97
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1144748:KS2013 RS01540
gene id: 1144748:KS2013_RS01540
uniprot id: A0A1B3B8F4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

1144748:KS2013 RS05670
gene id: 1144748:KS2013_RS05670
uniprot id: A0A1B3BAL8
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

1144748:KS2013 RS06380
gene id: 1144748:KS2013_RS06380
uniprot id: A0A1B3BB07
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1144748:KS2013 RS03350
gene id: 1144748:KS2013_RS03350
uniprot id: A0A1B3B9C6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinylarginine dihydrolase family.
messages: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
messages: Homodimer.

1144748:KS2013 RS05545
gene id: 1144748:KS2013_RS05545
uniprot id: A0A1B3BAI8
names: Similarity
messages: Belongs to the peptidase S8 family.

1144748:KS2013 RS00790
gene id: 1144748:KS2013_RS00790
uniprot id: A0A1B3B7Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1144748:KS2013 RS06550
gene id: 1144748:KS2013_RS06550
uniprot id: A0A1B3BB53
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1144748:KS2013 RS02640
gene id: 1144748:KS2013_RS02640
uniprot id: A0A1B3B8Z3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the multicopper oxidase family.
messages: Binds 1 Cu(+) ion.
messages: Homotrimer.

1144748:KS2013 RS02620
gene id: 1144748:KS2013_RS02620
uniprot id: A0A1B3B8Z6
names: Subcellular Location Annotation
messages: Cytoplasm

1144748:KS2013 RS09965
gene id: 1144748:KS2013_RS09965
uniprot id: A0A1B3BD37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1144748:KS2013 RS07920
gene id: 1144748:KS2013_RS07920
uniprot id: A0A1B3BBV7
names: Subcellular Location Annotation
messages: Membrane

1144748:KS2013 RS02375
gene id: 1144748:KS2013_RS02375
uniprot id: A0A1B3B8U6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1144748:KS2013 RS00405
gene id: 1144748:KS2013_RS00405
uniprot id: A0A1B3B7P0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

1144748:KS2013 RS08225
gene id: 1144748:KS2013_RS08225
uniprot id: A0A1B3BC11
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1144748:KS2013 RS06135
gene id: 1144748:KS2013_RS06135
uniprot id: A0A1B3BAV8
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

1144748:KS2013 RS05340
gene id: 1144748:KS2013_RS05340
uniprot id: A0A1B3BAE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1144748:KS2013 RS11055
gene id: 1144748:KS2013_RS11055
uniprot id: A0A1B3BDK8
names: Subcellular Location Annotation
messages: Membrane

1144748:KS2013 RS09360
gene id: 1144748:KS2013_RS09360
uniprot id: A0A1B3BCM3
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.

1144748:KS2013 RS05255
gene id: 1144748:KS2013_RS05255
uniprot id: A0A1B3BAA6
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

1144748:KS2013 RS04840
gene id: 1144748:KS2013_RS04840
uniprot id: A0A1B3BA39
names: Function
names: Subcellular Location Annotation
messages: Periplasm
messages: Transfers electrons from cytochrome c551 to cytochrome oxidase.

1144748:KS2013 RS06500
gene id: 1144748:KS2013_RS06500
uniprot id: A0A1B3BB44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1144748:KS2013 RS09870
gene id: 1144748:KS2013_RS09870
uniprot id: A0A1B3BCW0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144748:KS2013 RS03455
gene id: 1144748:KS2013_RS03455
uniprot id: A0A1B3B9E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1144748:KS2013 RS01135
gene id: 1144748:KS2013_RS01135
uniprot id: A0A1B3B872
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1144748:KS2013 RS01920
gene id: 1144748:KS2013_RS01920
uniprot id: A0A1B3B8L3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1144748:KS2013 RS01885
gene id: 1144748:KS2013_RS01885
uniprot id: A0A1B3B8G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1144748:KS2013 RS04710
gene id: 1144748:KS2013_RS04710
uniprot id: A0A1B3BA49
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

1144748:KS2013 RS04180
gene id: 1144748:KS2013_RS04180
uniprot id: A0A1B3B9S3
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1144748:KS2013 RS06895
gene id: 1144748:KS2013_RS06895
uniprot id: A0A1B3BB98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0761 family.
messages: Cell membrane
messages: Membrane

1144748:KS2013 RS06940
gene id: 1144748:KS2013_RS06940
uniprot id: A0A1B3BBB1
names: Similarity
messages: Belongs to the TrpC family.
messages: Belongs to the TrpF family.

1144748:KS2013 RS10640
gene id: 1144748:KS2013_RS10640
uniprot id: A0A1B3BDG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1144748:KS2013 RS01625
gene id: 1144748:KS2013_RS01625
uniprot id: A0A1B3B8C6
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1144748:KS2013 RS08490
gene id: 1144748:KS2013_RS08490
uniprot id: A0A1B3BC64
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome
messages: Secreted

1144748:KS2013 RS00630
gene id: 1144748:KS2013_RS00630
uniprot id: A0A1B3B7V3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1144748:KS2013 RS03665
gene id: 1144748:KS2013_RS03665
uniprot id: A0A1B3B9H2
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

1144748:KS2013 RS11630
gene id: 1144748:KS2013_RS11630
uniprot id: A0A1B3BE77
names: Similarity
messages: Belongs to the Smg family.

1144748:KS2013 RS08045
gene id: 1144748:KS2013_RS08045
uniprot id: A0A1B3BBY1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1144748:KS2013 RS01905
gene id: 1144748:KS2013_RS01905
uniprot id: A0A1B3B8H6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1144748:KS2013 RS09300
gene id: 1144748:KS2013_RS09300
uniprot id: A0A1B3BCK9
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

1144748:KS2013 RS06765
gene id: 1144748:KS2013_RS06765
uniprot id: A0A1B3BB75
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

1144748:KS2013 RS01035
gene id: 1144748:KS2013_RS01035
uniprot id: A0A1B3B814
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1144748:KS2013 RS10465
gene id: 1144748:KS2013_RS10465
uniprot id: A0A1B3BD59
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1144748:KS2013 RS01150
gene id: 1144748:KS2013_RS01150
uniprot id: A0A1B3B835
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1144748:KS2013 RS08455
gene id: 1144748:KS2013_RS08455
uniprot id: A0A1B3BC44
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1144748:KS2013 RS07210
gene id: 1144748:KS2013_RS07210
uniprot id: A0A1B3BBG1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1144748:KS2013 RS08860
gene id: 1144748:KS2013_RS08860
uniprot id: A0A1B3BCC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1144748:KS2013 RS07520
gene id: 1144748:KS2013_RS07520
uniprot id: A0A1B3BBQ8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144748:KS2013 RS11140
gene id: 1144748:KS2013_RS11140
uniprot id: A0A1B3BDR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1144748:KS2013 RS07575
gene id: 1144748:KS2013_RS07575
uniprot id: A0A1B3BBP3
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1144748:KS2013 RS05345
gene id: 1144748:KS2013_RS05345
uniprot id: A0A1B3BAF9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1144748:KS2013 RS00125
gene id: 1144748:KS2013_RS00125
uniprot id: A0A1B3B7K1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1144748:KS2013 RS11675
gene id: 1144748:KS2013_RS11675
uniprot id: A0A1B3BDW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

1144748:KS2013 RS01915
gene id: 1144748:KS2013_RS01915
uniprot id: A0A1B3B8K9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144748:KS2013 RS06870
gene id: 1144748:KS2013_RS06870
uniprot id: A0A1B3BBA0
names: Similarity
messages: Belongs to the PhoH family.

1144748:KS2013 RS05525
gene id: 1144748:KS2013_RS05525
uniprot id: A0A1B3BAL6
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1144748:KS2013 RS08185
gene id: 1144748:KS2013_RS08185
uniprot id: A0A1B3BBZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1144748:KS2013 RS01800
gene id: 1144748:KS2013_RS01800
uniprot id: A0A1B3B8G7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1144748:KS2013 RS05495
gene id: 1144748:KS2013_RS05495
uniprot id: A0A1B3BAH8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1144748:KS2013 RS08950
gene id: 1144748:KS2013_RS08950
uniprot id: A0A1B3BCE1
names: Similarity
messages: Belongs to the UPF0102 family.

1144748:KS2013 RS09530
gene id: 1144748:KS2013_RS09530
uniprot id: A0A1B3BCV1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Involved in the heme biosynthesis. Catalyzes the anaerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen III to yield the vinyl groups in protoporphyrinogen IX.
messages: Monomer.

1144748:KS2013 RS08540
gene id: 1144748:KS2013_RS08540
uniprot id: A0A1B3BC68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1144748:KS2013 RS11075
gene id: 1144748:KS2013_RS11075
uniprot id: A0A1B3BDT6
names: Cofactor
names: Similarity
messages: Belongs to the AspA/AstE family. Aspartoacylase subfamily.
messages: Binds 1 zinc ion per subunit.

1144748:KS2013 RS01390
gene id: 1144748:KS2013_RS01390
uniprot id: A0A1B3B886
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1144748:KS2013 RS06445
gene id: 1144748:KS2013_RS06445
uniprot id: A0A1B3BB34
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1144748:KS2013 RS03670
gene id: 1144748:KS2013_RS03670
uniprot id: A0A1B3B9J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1144748:KS2013 RS04000
gene id: 1144748:KS2013_RS04000
uniprot id: A0A1B3B9Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1144748:KS2013 RS04225
gene id: 1144748:KS2013_RS04225
uniprot id: A0A1B3B9S6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1144748:KS2013 RS00805
gene id: 1144748:KS2013_RS00805
uniprot id: A0A1B3B7W9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1144748:KS2013 RS02290
gene id: 1144748:KS2013_RS02290
uniprot id: A0A1B3B8P7
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

1144748:KS2013 RS10920
gene id: 1144748:KS2013_RS10920
uniprot id: A0A1B3BDL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1144748:KS2013 RS01060
gene id: 1144748:KS2013_RS01060
uniprot id: A0A1B3B843
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1144748:KS2013 RS06225
gene id: 1144748:KS2013_RS06225
uniprot id: A0A1B3BAX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

1144748:KS2013 RS10480
gene id: 1144748:KS2013_RS10480
uniprot id: A0A1B3BDL0
names: Similarity
messages: Belongs to the UPF0250 family.

1144748:KS2013 RS01855
gene id: 1144748:KS2013_RS01855
uniprot id: A0A1B3B8G8
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

1144748:KS2013 RS09990
gene id: 1144748:KS2013_RS09990
uniprot id: A0A1B3BD20
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1144748:KS2013 RS02125
gene id: 1144748:KS2013_RS02125
uniprot id: A0A1B3B8Q1
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1144748:KS2013 RS09855
gene id: 1144748:KS2013_RS09855
uniprot id: A0A1B3BCY5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1144748:KS2013 RS00600
gene id: 1144748:KS2013_RS00600
uniprot id: A0A1B3B7T2
names: Similarity
messages: Belongs to the peptidase S8 family.

1144748:KS2013 RS10095
gene id: 1144748:KS2013_RS10095
uniprot id: A0A1B3BD40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1144748:KS2013 RS01490
gene id: 1144748:KS2013_RS01490
uniprot id: A0A1B3B8E8
names: Function
names: Similarity
messages: Belongs to the GSP L family.
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.

1144748:KS2013 RS04260
gene id: 1144748:KS2013_RS04260
uniprot id: A0A1B3B9Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1144748:KS2013 RS09760
gene id: 1144748:KS2013_RS09760
uniprot id: A0A1B3BCW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

1144748:KS2013 RS03050
gene id: 1144748:KS2013_RS03050
uniprot id: A0A1B3B960
names: Subcellular Location Annotation
messages: Membrane

1144748:KS2013 RS06645
gene id: 1144748:KS2013_RS06645
uniprot id: A0A1B3BB92
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1144748:KS2013 RS02650
gene id: 1144748:KS2013_RS02650
uniprot id: A0A1B3B8X9
names: Similarity
messages: Belongs to the SCO1/2 family.

1144748:KS2013 RS02575
gene id: 1144748:KS2013_RS02575
uniprot id: A0A1B3B8W5
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1144748:KS2013 RS02740
gene id: 1144748:KS2013_RS02740
uniprot id: A0A1B3B906
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1144748:KS2013 RS01140
gene id: 1144748:KS2013_RS01140
uniprot id: A0A1B3B844
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1144748:KS2013 RS01725
gene id: 1144748:KS2013_RS01725
uniprot id: A0A1B3B8E3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144748:KS2013 RS09660
gene id: 1144748:KS2013_RS09660
uniprot id: A0A1B3BCT3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1144748:KS2013 RS04420
gene id: 1144748:KS2013_RS04420
uniprot id: A0A1B3B9W3
names: Similarity
messages: Belongs to the PrpD family.

1144748:KS2013 RS05070
gene id: 1144748:KS2013_RS05070
uniprot id: A0A1B3BAG6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144748:KS2013 RS01705
gene id: 1144748:KS2013_RS01705
uniprot id: A0A1B3B8E2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1144748:KS2013 RS05755
gene id: 1144748:KS2013_RS05755
uniprot id: A0A1B3BAP8
names: Similarity
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.

1144748:KS2013 RS02755
gene id: 1144748:KS2013_RS02755
uniprot id: A0A1B3B945
names: Function
names: Similarity
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.

1144748:KS2013 RS11650
gene id: 1144748:KS2013_RS11650
uniprot id: A0A1B3BDW7
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1144748:KS2013 RS09505
gene id: 1144748:KS2013_RS09505
uniprot id: A0A1B3BCP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1144748:KS2013 RS03205
gene id: 1144748:KS2013_RS03205
uniprot id: A0A1B3B993
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0283 family.
messages: Cell inner membrane
messages: Membrane

1144748:KS2013 RS02395
gene id: 1144748:KS2013_RS02395
uniprot id: A0A1B3B8U8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

1144748:KS2013 RS10780
gene id: 1144748:KS2013_RS10780
uniprot id: A0A1B3BDR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1144748:KS2013 RS11070
gene id: 1144748:KS2013_RS11070
uniprot id: A0A1B3BDI1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144748:KS2013 RS03460
gene id: 1144748:KS2013_RS03460
uniprot id: A0A1B3B9D4
names: Similarity
messages: Belongs to the GSP E family.

1144748:KS2013 RS00945
gene id: 1144748:KS2013_RS00945
uniprot id: A0A1B3B812
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1144748:KS2013 RS10970
gene id: 1144748:KS2013_RS10970
uniprot id: A0A1B3BDM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1144748:KS2013 RS01745
gene id: 1144748:KS2013_RS01745
uniprot id: A0A1B3B8J8
names: Similarity
messages: Belongs to the peptidase S8 family.

1144748:KS2013 RS11085
gene id: 1144748:KS2013_RS11085
uniprot id: A0A1B3BDW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1144748:KS2013 RS07315
gene id: 1144748:KS2013_RS07315
uniprot id: A0A1B3BBH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1144748:KS2013 RS07755
gene id: 1144748:KS2013_RS07755
uniprot id: A0A1B3BBT9
names: Similarity
messages: Belongs to the UPF0178 family.

1144748:KS2013 RS10045
gene id: 1144748:KS2013_RS10045
uniprot id: A0A1B3BD23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1144748:KS2013 RS02490
gene id: 1144748:KS2013_RS02490
uniprot id: A0A1B3B8T9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1144748:KS2013 RS07535
gene id: 1144748:KS2013_RS07535
uniprot id: A0A1B3BBN3
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

1144748:KS2013 RS03920
gene id: 1144748:KS2013_RS03920
uniprot id: A0A1B3B9U3
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Tetramer of two alpha and two beta subunits.

1144748:KS2013 RS01860
gene id: 1144748:KS2013_RS01860
uniprot id: A0A1B3B8H2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1144748:KS2013 RS11690
gene id: 1144748:KS2013_RS11690
uniprot id: A0A1B3BDW1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

1144748:KS2013 RS00910
gene id: 1144748:KS2013_RS00910
uniprot id: A0A1B3B7Z3
names: Caution
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144748:KS2013 RS00555
gene id: 1144748:KS2013_RS00555
uniprot id: A0A1B3B7S5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1144748:KS2013 RS01840
gene id: 1144748:KS2013_RS01840
uniprot id: A0A1B3B8J1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

1144748:KS2013 RS05380
gene id: 1144748:KS2013_RS05380
uniprot id: A0A1B3BAF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CysZ family.
messages: Cell inner membrane
messages: High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway.

1144748:KS2013 RS00010
gene id: 1144748:KS2013_RS00010
uniprot id: A0A1B3B7G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1144748:KS2013 RS05470
gene id: 1144748:KS2013_RS05470
uniprot id: A0A1B3BAI5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1144748:KS2013 RS07495
gene id: 1144748:KS2013_RS07495
uniprot id: A0A1B3BBM3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1144748:KS2013 RS07220
gene id: 1144748:KS2013_RS07220
uniprot id: A0A1B3BBI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1144748:KS2013 RS06305
gene id: 1144748:KS2013_RS06305
uniprot id: A0A1B3BAZ2
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1144748:KS2013 RS11060
gene id: 1144748:KS2013_RS11060
uniprot id: A0A1B3BDJ7
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1144748:KS2013 RS03180
gene id: 1144748:KS2013_RS03180
uniprot id: A0A1B3B983
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1144748:KS2013 RS07300
gene id: 1144748:KS2013_RS07300
uniprot id: A0A1B3BBJ0
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

1144748:KS2013 RS03895
gene id: 1144748:KS2013_RS03895
uniprot id: A0A1B3B9L4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1144748:KS2013 RS11685
gene id: 1144748:KS2013_RS11685
uniprot id: A0A1B3BE20
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1144748:KS2013 RS07305
gene id: 1144748:KS2013_RS07305
uniprot id: A0A1B3BBI5
names: Subcellular Location Annotation
messages: Membrane

1144748:KS2013 RS04970
gene id: 1144748:KS2013_RS04970
uniprot id: A0A1B3BAE6
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1144748:KS2013 RS03740
gene id: 1144748:KS2013_RS03740
uniprot id: A0A1B3B9N4
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

1144748:KS2013 RS01050
gene id: 1144748:KS2013_RS01050
uniprot id: A0A1B3B820
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1144748:KS2013 RS04510
gene id: 1144748:KS2013_RS04510
uniprot id: A0A1B3BA28
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1144748:KS2013 RS01530
gene id: 1144748:KS2013_RS01530
uniprot id: A0A1B3B899
names: Similarity
messages: Belongs to the peptidase S41A family.

1144748:KS2013 RS05195
gene id: 1144748:KS2013_RS05195
uniprot id: A0A1B3BAB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

1144748:KS2013 RS11500
gene id: 1144748:KS2013_RS11500
uniprot id: A0A1B3BDV3
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1144748:KS2013 RS06790
gene id: 1144748:KS2013_RS06790
uniprot id: A0A1B3BB79
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1144748:KS2013 RS06875
gene id: 1144748:KS2013_RS06875
uniprot id: A0A1B3BB96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1144748:KS2013 RS11885
gene id: 1144748:KS2013_RS11885
uniprot id: A0A1B3BDY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1144748:KS2013 RS00730
gene id: 1144748:KS2013_RS00730
uniprot id: A0A1B3B7X5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1144748:KS2013 RS02095
gene id: 1144748:KS2013_RS02095
uniprot id: A0A1B3B8L2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1144748:KS2013 RS08790
gene id: 1144748:KS2013_RS08790
uniprot id: A0A1B3BCB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

1144748:KS2013 RS08780
gene id: 1144748:KS2013_RS08780
uniprot id: A0A1B3BCC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1144748:KS2013 RS01735
gene id: 1144748:KS2013_RS01735
uniprot id: A0A1B3B8E1
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1144748:KS2013 RS10695
gene id: 1144748:KS2013_RS10695
uniprot id: A0A1B3BDB2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1144748:KS2013 RS05570
gene id: 1144748:KS2013_RS05570
uniprot id: A0A1B3BAK6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

1144748:KS2013 RS04875
gene id: 1144748:KS2013_RS04875
uniprot id: A0A1B3BA50
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

1144748:KS2013 RS01975
gene id: 1144748:KS2013_RS01975
uniprot id: A0A1B3B8M3
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
messages: The transmembrane domain is a dimerization domain.

1144748:KS2013 RS09175
gene id: 1144748:KS2013_RS09175
uniprot id: A0A1B3BCP4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1144748:KS2013 RS06900
gene id: 1144748:KS2013_RS06900
uniprot id: A0A1B3BB97
names: Similarity
messages: Belongs to the ArsC family.

1144748:KS2013 RS06460
gene id: 1144748:KS2013_RS06460
uniprot id: A0A1B3BB17
names: Similarity
messages: Belongs to the P(II) protein family.

1144748:KS2013 RS06585
gene id: 1144748:KS2013_RS06585
uniprot id: A0A1B3BB65
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

1144748:KS2013 RS04955
gene id: 1144748:KS2013_RS04955
uniprot id: A0A1B3BAA8
names: Similarity
messages: Belongs to the HesB/IscA family.

1144748:KS2013 RS07090
gene id: 1144748:KS2013_RS07090
uniprot id: A0A1B3BBD4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1144748:KS2013 RS03400
gene id: 1144748:KS2013_RS03400
uniprot id: A0A1B3B9D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

1144748:KS2013 RS00705
gene id: 1144748:KS2013_RS00705
uniprot id: A0A1B3B7V0
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1144748:KS2013 RS11705
gene id: 1144748:KS2013_RS11705
uniprot id: A0A1B3BDY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1144748:KS2013 RS03845
gene id: 1144748:KS2013_RS03845
uniprot id: A0A1B3B9L6
names: Similarity
messages: Belongs to the glyoxalase I family.

1144748:KS2013 RS09900
gene id: 1144748:KS2013_RS09900
uniprot id: A0A1B3BCZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1144748:KS2013 RS07925
gene id: 1144748:KS2013_RS07925
uniprot id: A0A1B3BBW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1144748:KS2013 RS09825
gene id: 1144748:KS2013_RS09825
uniprot id: A0A1B3BD04
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1144748:KS2013 RS02300
gene id: 1144748:KS2013_RS02300
uniprot id: A0A1B3B8W2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144748:KS2013 RS03910
gene id: 1144748:KS2013_RS03910
uniprot id: A0A1B3B9L8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1144748:KS2013 RS06280
gene id: 1144748:KS2013_RS06280
uniprot id: A0A1B3BAZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1144748:KS2013 RS07670
gene id: 1144748:KS2013_RS07670
uniprot id: A0A1B3BBQ6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

1144748:KS2013 RS10510
gene id: 1144748:KS2013_RS10510
uniprot id: A0A1B3BDE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

1144748:KS2013 RS03150
gene id: 1144748:KS2013_RS03150
uniprot id: A0A1B3B988
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1144748:KS2013 RS04880
gene id: 1144748:KS2013_RS04880
uniprot id: A0A1B3BA85
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

1144748:KS2013 RS01415
gene id: 1144748:KS2013_RS01415
uniprot id: A0A1B3B885
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

1144748:KS2013 RS00900
gene id: 1144748:KS2013_RS00900
uniprot id: A0A1B3B7Y9
names: Subcellular Location Annotation
messages: Cell inner membrane

1144748:KS2013 RS00960
gene id: 1144748:KS2013_RS00960
uniprot id: A0A1B3B801
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
messages: Cell membrane
messages: Forms a complex with DabB.
messages: Part of an energy-coupled inorganic carbon pump.

1144748:KS2013 RS04515
gene id: 1144748:KS2013_RS04515
uniprot id: A0A1B3B9Y8
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1144748:KS2013 RS00355
gene id: 1144748:KS2013_RS00355
uniprot id: A0A1B3B7N2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1144748:KS2013 RS08260
gene id: 1144748:KS2013_RS08260
uniprot id: A0A1B3BC25
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1144748:KS2013 RS01205
gene id: 1144748:KS2013_RS01205
uniprot id: A0A1B3B864
names: Subcellular Location Annotation
messages: Membrane

1144748:KS2013 RS01545
gene id: 1144748:KS2013_RS01545
uniprot id: A0A1B3B8B5
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1144748:KS2013 RS02480
gene id: 1144748:KS2013_RS02480
uniprot id: A0A1B3B8U5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144748:KS2013 RS05005
gene id: 1144748:KS2013_RS05005
uniprot id: A0A1B3BA73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1144748:KS2013 RS08900
gene id: 1144748:KS2013_RS08900
uniprot id: A0A1B3BCF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1144748:KS2013 RS05220
gene id: 1144748:KS2013_RS05220
uniprot id: A0A1B3BAF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1144748:KS2013 RS10730
gene id: 1144748:KS2013_RS10730
uniprot id: A0A1B3BDD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

1144748:KS2013 RS10030
gene id: 1144748:KS2013_RS10030
uniprot id: A0A1B3BD40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1144748:KS2013 RS04355
gene id: 1144748:KS2013_RS04355
uniprot id: A0A1B3B9V8
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1144748:KS2013 RS05010
gene id: 1144748:KS2013_RS05010
uniprot id: A0A1B3BA65
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144748:KS2013 RS02440
gene id: 1144748:KS2013_RS02440
uniprot id: A0A1B3B8T1
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1144748:KS2013 RS10320
gene id: 1144748:KS2013_RS10320
uniprot id: A0A1B3BD90
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144748:KS2013 RS09500
gene id: 1144748:KS2013_RS09500
uniprot id: A0A1B3BCQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

1144748:KS2013 RS10625
gene id: 1144748:KS2013_RS10625
uniprot id: A0A1B3BDB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1144748:KS2013 RS02085
gene id: 1144748:KS2013_RS02085
uniprot id: A0A1B3B8L4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1144748:KS2013 RS10520
gene id: 1144748:KS2013_RS10520
uniprot id: A0A1B3BDC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1144748:KS2013 RS08665
gene id: 1144748:KS2013_RS08665
uniprot id: A0A1B3BCE2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
messages: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1144748:KS2013 RS11310
gene id: 1144748:KS2013_RS11310
uniprot id: A0A1B3BDQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

1144748:KS2013 RS07165
gene id: 1144748:KS2013_RS07165
uniprot id: A0A1B3BBG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1144748:KS2013 RS04145
gene id: 1144748:KS2013_RS04145
uniprot id: A0A1B3B9Y7
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.

1144748:KS2013 RS11855
gene id: 1144748:KS2013_RS11855
uniprot id: A0A1B3BCW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1144748:KS2013 RS09065
gene id: 1144748:KS2013_RS09065
uniprot id: A0A1B3BCG2
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

1144748:KS2013 RS10685
gene id: 1144748:KS2013_RS10685
uniprot id: A0A1B3BDP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1144748:KS2013 RS03725
gene id: 1144748:KS2013_RS03725
uniprot id: A0A1B3B9K5
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

1144748:KS2013 RS10900
gene id: 1144748:KS2013_RS10900
uniprot id: A0A1B3BDI6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1144748:KS2013 RS05460
gene id: 1144748:KS2013_RS05460
uniprot id: A0A1B3BAI7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1144748:KS2013 RS04965
gene id: 1144748:KS2013_RS04965
uniprot id: A0A1B3BA99
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

1144748:KS2013 RS01360
gene id: 1144748:KS2013_RS01360
uniprot id: A0A1B3B877
names: Subcellular Location Annotation
messages: Membrane

1144748:KS2013 RS08990
gene id: 1144748:KS2013_RS08990
uniprot id: A0A1B3BCF6
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1144748:KS2013 RS09545
gene id: 1144748:KS2013_RS09545
uniprot id: A0A1B3BCW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1144748:KS2013 RS07380
gene id: 1144748:KS2013_RS07380
uniprot id: A0A1B3BBJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. WecA subfamily.
messages: Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55).
messages: Cell inner membrane
messages: Membrane

1144748:KS2013 RS00690
gene id: 1144748:KS2013_RS00690
uniprot id: A0A1B3B7U8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1144748:KS2013 RS03590
gene id: 1144748:KS2013_RS03590
uniprot id: A0A1B3B9G4
names: Function
names: Similarity
messages: Belongs to the peptidase M16 family.
messages: Endopeptidase that degrades small peptides of less than 7 kDa, such as glucagon and insulin.

1144748:KS2013 RS07405
gene id: 1144748:KS2013_RS07405
uniprot id: A0A1B3BBK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RfaH family.
messages: Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components.
messages: Interacts with both the nontemplate DNA and the RNA polymerase (RNAP).

1144748:KS2013 RS01560
gene id: 1144748:KS2013_RS01560
uniprot id: A0A1B3B8D4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1144748:KS2013 RS11725
gene id: 1144748:KS2013_RS11725
uniprot id: A0A1B3BDX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1144748:KS2013 RS03010
gene id: 1144748:KS2013_RS03010
uniprot id: A0A1B3B952
names: Similarity
messages: Belongs to the peptidase S51 family.

1144748:KS2013 RS01580
gene id: 1144748:KS2013_RS01580
uniprot id: A0A1B3B8B1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1144748:KS2013 RS07885
gene id: 1144748:KS2013_RS07885
uniprot id: A0A1B3BBV4
names: Subcellular Location Annotation
messages: Membrane

1144748:KS2013 RS09685
gene id: 1144748:KS2013_RS09685
uniprot id: A0A1B3BCS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1144748:KS2013 RS03365
gene id: 1144748:KS2013_RS03365
uniprot id: A0A1B3B9B5
names: Caution
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1144748:KS2013 RS01750
gene id: 1144748:KS2013_RS01750
uniprot id: A0A1B3B8F7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1144748:KS2013 RS10070
gene id: 1144748:KS2013_RS10070
uniprot id: A0A1B3BD10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1144748:KS2013 RS11820
gene id: 1144748:KS2013_RS11820
uniprot id: A0A1B3B8V5
names: Similarity
messages: Belongs to the ketopantoate reductase family.

1144748:KS2013 RS02315
gene id: 1144748:KS2013_RS02315
uniprot id: A0A1B3B8Q5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1144748:KS2013 RS08235
gene id: 1144748:KS2013_RS08235
uniprot id: A0A1B3BC19
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144748:KS2013 RS01890
gene id: 1144748:KS2013_RS01890
uniprot id: A0A1B3B8J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1144748:KS2013 RS09050
gene id: 1144748:KS2013_RS09050
uniprot id: A0A1B3BCG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

1144748:KS2013 RS01925
gene id: 1144748:KS2013_RS01925
uniprot id: A0A1B3B8I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoid occlusion factor SlmA family.
messages: Homodimer. Interacts with FtsZ.
messages: Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
messages: nucleoid

1144748:KS2013 RS05145
gene id: 1144748:KS2013_RS05145
uniprot id: A0A1B3BA96
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

1144748:KS2013 RS05185
gene id: 1144748:KS2013_RS05185
uniprot id: A0A1B3BAB1
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1144748:KS2013 RS10590
gene id: 1144748:KS2013_RS10590
uniprot id: A0A1B3BD94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1144748:KS2013 RS04765
gene id: 1144748:KS2013_RS04765
uniprot id: A0A1B3BA57
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

1144748:KS2013 RS07750
gene id: 1144748:KS2013_RS07750
uniprot id: A0A1B3BBS0
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144748:KS2013 RS03305
gene id: 1144748:KS2013_RS03305
uniprot id: A0A1B3B9B0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: Multifunctional regulator of fatty acid metabolism.

1144748:KS2013 RS11040
gene id: 1144748:KS2013_RS11040
uniprot id: A0A1B3BDI4
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1144748:KS2013 RS10475
gene id: 1144748:KS2013_RS10475
uniprot id: A0A1B3BD85
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1144748:KS2013 RS09365
gene id: 1144748:KS2013_RS09365
uniprot id: A0A1B3BCN9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

1144748:KS2013 RS02180
gene id: 1144748:KS2013_RS02180
uniprot id: A0A1B3B8R1
names: Subcellular Location Annotation
messages: Membrane

1144748:KS2013 RS10405
gene id: 1144748:KS2013_RS10405
uniprot id: A0A1B3BD76
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1144748:KS2013 RS03145
gene id: 1144748:KS2013_RS03145
uniprot id: A0A1B3B995
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1144748:KS2013 RS09630
gene id: 1144748:KS2013_RS09630
uniprot id: A0A1B3BCX1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1144748:KS2013 RS04255
gene id: 1144748:KS2013_RS04255
uniprot id: A0A1B3B9U0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1144748:KS2013 RS09340
gene id: 1144748:KS2013_RS09340
uniprot id: A0A1B3BCT9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1144748:KS2013 RS08870
gene id: 1144748:KS2013_RS08870
uniprot id: A0A1B3BCD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

1144748:KS2013 RS11605
gene id: 1144748:KS2013_RS11605
uniprot id: A0A1B3BDV9
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1144748:KS2013 RS05420
gene id: 1144748:KS2013_RS05420
uniprot id: A0A1B3BAH2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1144748:KS2013 RS02410
gene id: 1144748:KS2013_RS02410
uniprot id: A0A1B3B8T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

1144748:KS2013 RS06480
gene id: 1144748:KS2013_RS06480
uniprot id: A0A1B3BB46
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1144748:KS2013 RS07370
gene id: 1144748:KS2013_RS07370
uniprot id: A0A1B3BBK0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1144748:KS2013 RS03275
gene id: 1144748:KS2013_RS03275
uniprot id: A0A1B3B9F2
names: Subcellular Location Annotation
messages: Membrane

1144748:KS2013 RS09135
gene id: 1144748:KS2013_RS09135
uniprot id: A0A1B3BCN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1144748:KS2013 RS02340
gene id: 1144748:KS2013_RS02340
uniprot id: A0A1B3B8Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

1144748:KS2013 RS10440
gene id: 1144748:KS2013_RS10440
uniprot id: A0A1B3BD72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1144748:KS2013 RS05710
gene id: 1144748:KS2013_RS05710
uniprot id: A0A1B3BAP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1144748:KS2013 RS05855
gene id: 1144748:KS2013_RS05855
uniprot id: A0A1B3BAQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

1144748:KS2013 RS02890
gene id: 1144748:KS2013_RS02890
uniprot id: A0A1B3B941
names: Subcellular Location Annotation
messages: Membrane

1144748:KS2013 RS02570
gene id: 1144748:KS2013_RS02570
uniprot id: A0A1B3B8Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1144748:KS2013 RS08655
gene id: 1144748:KS2013_RS08655
uniprot id: A0A1B3BCE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1144748:KS2013 RS09820
gene id: 1144748:KS2013_RS09820
uniprot id: A0A1B3BCV3
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

1144748:KS2013 RS04785
gene id: 1144748:KS2013_RS04785
uniprot id: A0A1B3BA36
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1144748:KS2013 RS04660
gene id: 1144748:KS2013_RS04660
uniprot id: A0A1B3BA52
names: Similarity
messages: Belongs to the pyruvate kinase family.

1144748:KS2013 RS10830
gene id: 1144748:KS2013_RS10830
uniprot id: A0A1B3BDS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1144748:KS2013 RS11405
gene id: 1144748:KS2013_RS11405
uniprot id: A0A1B3BDS3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

1144748:KS2013 RS11585
gene id: 1144748:KS2013_RS11585
uniprot id: A0A1B3BE65
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1144748:KS2013 RS01115
gene id: 1144748:KS2013_RS01115
uniprot id: A0A1B3B824
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1144748:KS2013 RS10120
gene id: 1144748:KS2013_RS10120
uniprot id: A0A1B3BD34
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1144748:KS2013 RS10000
gene id: 1144748:KS2013_RS10000
uniprot id: A0A1B3BD11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1144748:KS2013 RS02105
gene id: 1144748:KS2013_RS02105
uniprot id: A0A1B3B8R6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1144748:KS2013 RS07995
gene id: 1144748:KS2013_RS07995
uniprot id: A0A1B3BBX0
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1144748:KS2013 RS09740
gene id: 1144748:KS2013_RS09740
uniprot id: A0A1B3BCZ8
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

1144748:KS2013 RS01000
gene id: 1144748:KS2013_RS01000
uniprot id: A0A1B3B810
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1144748:KS2013 RS06595
gene id: 1144748:KS2013_RS06595
uniprot id: A0A1B3BB86
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

1144748:KS2013 RS07055
gene id: 1144748:KS2013_RS07055
uniprot id: A0A1B3BBE0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1144748:KS2013 RS01110
gene id: 1144748:KS2013_RS01110
uniprot id: A0A1B3B825
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1144748:KS2013 RS06435
gene id: 1144748:KS2013_RS06435
uniprot id: A0A1B3BB14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1144748:KS2013 RS09595
gene id: 1144748:KS2013_RS09595
uniprot id: A0A1B3BCX3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M20A family. N-acetylcitrulline deacetylase subfamily.
messages: Binds 1 Co(2+) ion per subunit.
messages: Catalyzes the deacetylation of N-acetyl-L-citrulline to produce L-citrulline. This is a step in an alternative arginine biosynthesis pathway.

1144748:KS2013 RS01445
gene id: 1144748:KS2013_RS01445
uniprot id: A0A1B3B895
names: Similarity
messages: Belongs to the GSP C family.

1144748:KS2013 RS07080
gene id: 1144748:KS2013_RS07080
uniprot id: A0A1B3BBE6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1144748:KS2013 RS09585
gene id: 1144748:KS2013_RS09585
uniprot id: A0A1B3BCQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1144748:KS2013 RS09045
gene id: 1144748:KS2013_RS09045
uniprot id: A0A1B3BCG3
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1144748:KS2013 RS08250
gene id: 1144748:KS2013_RS08250
uniprot id: A0A1B3BC12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1144748:KS2013 RS09465
gene id: 1144748:KS2013_RS09465
uniprot id: A0A1B3BCR1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1144748:KS2013 RS02455
gene id: 1144748:KS2013_RS02455
uniprot id: A0A1B3B8U1
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

1144748:KS2013 RS05980
gene id: 1144748:KS2013_RS05980
uniprot id: A0A1B3BAS3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1144748:KS2013 RS02380
gene id: 1144748:KS2013_RS02380
uniprot id: A0A1B3B8S5
names: Subcellular Location Annotation
messages: Membrane

1144748:KS2013 RS05165
gene id: 1144748:KS2013_RS05165
uniprot id: A0A1B3BAE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0114 family.
messages: Cell membrane
messages: Membrane

1144748:KS2013 RS09650
gene id: 1144748:KS2013_RS09650
uniprot id: A0A1B3BCT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1144748:KS2013 RS00840
gene id: 1144748:KS2013_RS00840
uniprot id: A0A1B3B7Z0
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

1144748:KS2013 RS09160
gene id: 1144748:KS2013_RS09160
uniprot id: A0A1B3BCP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.
messages: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.

1144748:KS2013 RS04790
gene id: 1144748:KS2013_RS04790
uniprot id: A0A1B3BA30
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1144748:KS2013 RS06415
gene id: 1144748:KS2013_RS06415
uniprot id: A0A1B3BB11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1144748:KS2013 RS08460
gene id: 1144748:KS2013_RS08460
uniprot id: A0A1B3BCA6
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

1144748:KS2013 RS10040
gene id: 1144748:KS2013_RS10040
uniprot id: A0A1B3BD31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1144748:KS2013 RS05030
gene id: 1144748:KS2013_RS05030
uniprot id: A0A1B3BA75
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1144748:KS2013 RS10125
gene id: 1144748:KS2013_RS10125
uniprot id: A0A1B3BD30
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
messages: Belongs to the biotin--protein ligase family.

1144748:KS2013 RS00970
gene id: 1144748:KS2013_RS00970
uniprot id: A0A1B3B7Z8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144748:KS2013 RS11365
gene id: 1144748:KS2013_RS11365
uniprot id: A0A1B3BDW2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1144748:KS2013 RS11305
gene id: 1144748:KS2013_RS11305
uniprot id: A0A1B3BDQ7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1144748:KS2013 RS06775
gene id: 1144748:KS2013_RS06775
uniprot id: A0A1B3BB72
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1144748:KS2013 RS06860
gene id: 1144748:KS2013_RS06860
uniprot id: A0A1B3BBB9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1144748:KS2013 RS02935
gene id: 1144748:KS2013_RS02935
uniprot id: A0A1B3B949
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1144748:KS2013 RS08810
gene id: 1144748:KS2013_RS08810
uniprot id: A0A1B3BCB9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

1144748:KS2013 RS06340
gene id: 1144748:KS2013_RS06340
uniprot id: A0A1B3BB01
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Homotetramer.

1144748:KS2013 RS03445
gene id: 1144748:KS2013_RS03445
uniprot id: A0A1B3B9E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1144748:KS2013 RS08715
gene id: 1144748:KS2013_RS08715
uniprot id: A0A1B3BCF3
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1144748:KS2013 RS07035
gene id: 1144748:KS2013_RS07035
uniprot id: A0A1B3BBC4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1144748:KS2013 RS05860
gene id: 1144748:KS2013_RS05860
uniprot id: A0A1B3BAS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1144748:KS2013 RS02335
gene id: 1144748:KS2013_RS02335
uniprot id: A0A1B3B8S4
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1144748:KS2013 RS08970
gene id: 1144748:KS2013_RS08970
uniprot id: A0A1B3BCJ1
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

1144748:KS2013 RS08050
gene id: 1144748:KS2013_RS08050
uniprot id: A0A1B3BBY5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144748:KS2013 RS07375
gene id: 1144748:KS2013_RS07375
uniprot id: A0A1B3BBL5
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1144748:KS2013 RS04935
gene id: 1144748:KS2013_RS04935
uniprot id: A0A1B3BA63
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1144748:KS2013 RS10230
gene id: 1144748:KS2013_RS10230
uniprot id: A0A1B3BDG2
names: Similarity
messages: Belongs to the UPF0145 family.

1144748:KS2013 RS09730
gene id: 1144748:KS2013_RS09730
uniprot id: A0A1B3BCT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1144748:KS2013 RS06580
gene id: 1144748:KS2013_RS06580
uniprot id: A0A1B3BB42
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1144748:KS2013 RS09940
gene id: 1144748:KS2013_RS09940
uniprot id: A0A1B3BD09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1144748:KS2013 RS01095
gene id: 1144748:KS2013_RS01095
uniprot id: A0A1B3B826
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1144748:KS2013 RS06685
gene id: 1144748:KS2013_RS06685
uniprot id: A0A1B3BB77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1144748:KS2013 RS07870
gene id: 1144748:KS2013_RS07870
uniprot id: A0A1B3BBV2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1144748:KS2013 RS06915
gene id: 1144748:KS2013_RS06915
uniprot id: A0A1B3BBC8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

1144748:KS2013 RS08905
gene id: 1144748:KS2013_RS08905
uniprot id: A0A1B3BCJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1144748:KS2013 RS11285
gene id: 1144748:KS2013_RS11285
uniprot id: A0A1B3BE06
names: Similarity
messages: Belongs to the YkuD family.

1144748:KS2013 RS11020
gene id: 1144748:KS2013_RS11020
uniprot id: A0A1B3BDN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1144748:KS2013 RS07490
gene id: 1144748:KS2013_RS07490
uniprot id: A0A1B3BBM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1144748:KS2013 RS10495
gene id: 1144748:KS2013_RS10495
uniprot id: A0A1B3BDA9
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1144748:KS2013 RS03765
gene id: 1144748:KS2013_RS03765
uniprot id: A0A1B3B9J8
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

1144748:KS2013 RS06530
gene id: 1144748:KS2013_RS06530
uniprot id: A0A1B3BB33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribosome modulation factor family.
messages: Cytoplasm
messages: During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes).

1144748:KS2013 RS06920
gene id: 1144748:KS2013_RS06920
uniprot id: A0A1B3BBD1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1144748:KS2013 RS10175
gene id: 1144748:KS2013_RS10175
uniprot id: A0A1B3BDF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1144748:KS2013 RS07625
gene id: 1144748:KS2013_RS07625
uniprot id: A0A1B3BBQ1
names: Similarity
messages: Belongs to the YciI family.

1144748:KS2013 RS04820
gene id: 1144748:KS2013_RS04820
uniprot id: A0A1B3BAA7
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

1144748:KS2013 RS05840
gene id: 1144748:KS2013_RS05840
uniprot id: A0A1B3BAR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1144748:KS2013 RS05845
gene id: 1144748:KS2013_RS05845
uniprot id: A0A1B3BAP3
names: Subcellular Location Annotation
messages: Membrane

1144748:KS2013 RS01270
gene id: 1144748:KS2013_RS01270
uniprot id: A0A1B3B851
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1144748:KS2013 RS10345
gene id: 1144748:KS2013_RS10345
uniprot id: A0A1B3BD84
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1144748:KS2013 RS07040
gene id: 1144748:KS2013_RS07040
uniprot id: A0A1B3BBC6
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

1144748:KS2013 RS11345
gene id: 1144748:KS2013_RS11345
uniprot id: A0A1B3BDP4
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1144748:KS2013 RS10845
gene id: 1144748:KS2013_RS10845
uniprot id: A0A1B3BDH9
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

1144748:KS2013 RS04520
gene id: 1144748:KS2013_RS04520
uniprot id: A0A1B3B9X9
names: Subcellular Location Annotation
messages: Membrane

1144748:KS2013 RS06560
gene id: 1144748:KS2013_RS06560
uniprot id: A0A1B3BB35
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1144748:KS2013 RS03090
gene id: 1144748:KS2013_RS03090
uniprot id: A0A1B3B979
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1144748:KS2013 RS09400
gene id: 1144748:KS2013_RS09400
uniprot id: A0A1B3BCM9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1144748:KS2013 RS07975
gene id: 1144748:KS2013_RS07975
uniprot id: A0A1B3BBX2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1144748:KS2013 RS05445
gene id: 1144748:KS2013_RS05445
uniprot id: A0A1B3BAH4
names: Similarity
messages: Belongs to the fructosamine kinase family.

1144748:KS2013 RS06035
gene id: 1144748:KS2013_RS06035
uniprot id: A0A1B3BAX5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Transforms N(2)-succinylglutamate into succinate and glutamate.

1144748:KS2013 RS04230
gene id: 1144748:KS2013_RS04230
uniprot id: A0A1B3B9T0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1144748:KS2013 RS08770
gene id: 1144748:KS2013_RS08770
uniprot id: A0A1B3BCB0
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1144748:KS2013 RS06750
gene id: 1144748:KS2013_RS06750
uniprot id: A0A1B3BB78
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1144748:KS2013 RS05215
gene id: 1144748:KS2013_RS05215
uniprot id: A0A1B3BAF0
names: Similarity
messages: Belongs to the peptidase S24 family.

1144748:KS2013 RS09100
gene id: 1144748:KS2013_RS09100
uniprot id: A0A1B3BCH1
names: Similarity
messages: Belongs to the peptidase U62 family.

1144748:KS2013 RS06080
gene id: 1144748:KS2013_RS06080
uniprot id: A0A1B3BAU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1144748:KS2013 RS06060
gene id: 1144748:KS2013_RS06060
uniprot id: A0A1B3BAV1
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1144748:KS2013 RS02210
gene id: 1144748:KS2013_RS02210
uniprot id: A0A1B3B8P3
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

1144748:KS2013 RS03245
gene id: 1144748:KS2013_RS03245
uniprot id: A0A1B3B9B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1144748:KS2013 RS10990
gene id: 1144748:KS2013_RS10990
uniprot id: A0A1B3BDH1
names: Similarity
messages: Belongs to the GSP E family.

1144748:KS2013 RS05020
gene id: 1144748:KS2013_RS05020
uniprot id: A0A1B3BAA4
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1144748:KS2013 RS11030
gene id: 1144748:KS2013_RS11030
uniprot id: A0A1B3BDV8
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144748:KS2013 RS10975
gene id: 1144748:KS2013_RS10975
uniprot id: A0A1B3BDI5
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1144748:KS2013 RS05540
gene id: 1144748:KS2013_RS05540
uniprot id: A0A1B3BAK5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1144748:KS2013 RS08595
gene id: 1144748:KS2013_RS08595
uniprot id: A0A1B3BC72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

1144748:KS2013 RS01895
gene id: 1144748:KS2013_RS01895
uniprot id: A0A1B3B8M8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1144748:KS2013 RS05385
gene id: 1144748:KS2013_RS05385
uniprot id: A0A1B3BAL0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1144748:KS2013 RS09665
gene id: 1144748:KS2013_RS09665
uniprot id: A0A1B3BCU9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1144748:KS2013 RS10305
gene id: 1144748:KS2013_RS10305
uniprot id: A0A1B3BD58
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 3-HAO family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
messages: Homodimer.

1144748:KS2013 RS03635
gene id: 1144748:KS2013_RS03635
uniprot id: A0A1B3B9L3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144748:KS2013 RS02430
gene id: 1144748:KS2013_RS02430
uniprot id: A0A1B3B8T5
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

1144748:KS2013 RS03265
gene id: 1144748:KS2013_RS03265
uniprot id: A0A1B3B996
names: Subcellular Location Annotation
messages: Membrane

1144748:KS2013 RS09995
gene id: 1144748:KS2013_RS09995
uniprot id: A0A1B3BD15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1144748:KS2013 RS07845
gene id: 1144748:KS2013_RS07845
uniprot id: A0A1B3BBV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1144748:KS2013 RS05825
gene id: 1144748:KS2013_RS05825
uniprot id: A0A1B3BAS8
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1144748:KS2013 RS03115
gene id: 1144748:KS2013_RS03115
uniprot id: A0A1B3B9C1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1144748:KS2013 RS09640
gene id: 1144748:KS2013_RS09640
uniprot id: A0A1B3BD17
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1144748:KS2013 RS09675
gene id: 1144748:KS2013_RS09675
uniprot id: A0A1B3BCS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1144748:KS2013 RS07850
gene id: 1144748:KS2013_RS07850
uniprot id: A0A1B3BBU1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1144748:KS2013 RS11100
gene id: 1144748:KS2013_RS11100
uniprot id: A0A1B3BDM9
names: Subcellular Location Annotation
messages: Membrane

1144748:KS2013 RS04125
gene id: 1144748:KS2013_RS04125
uniprot id: A0A1B3B9R8
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1144748:KS2013 RS11645
gene id: 1144748:KS2013_RS11645
uniprot id: A0A1B3BDY3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1144748:KS2013 RS06345
gene id: 1144748:KS2013_RS06345
uniprot id: A0A1B3BAZ7
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1144748:KS2013 RS06330
gene id: 1144748:KS2013_RS06330
uniprot id: A0A1B3BAZ4
names: Subcellular Location Annotation
messages: Membrane

1144748:KS2013 RS02220
gene id: 1144748:KS2013_RS02220
uniprot id: A0A1B3B8N8
names: Similarity
messages: Belongs to the aspartokinase family.

1144748:KS2013 RS00020
gene id: 1144748:KS2013_RS00020
uniprot id: A0A1B3B7G9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1144748:KS2013 RS05455
gene id: 1144748:KS2013_RS05455
uniprot id: A0A1B3BAH6
names: Subcellular Location Annotation
messages: Membrane

1144748:KS2013 RS09970
gene id: 1144748:KS2013_RS09970
uniprot id: A0A1B3BCY7
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1144748:KS2013 RS07690
gene id: 1144748:KS2013_RS07690
uniprot id: A0A1B3BBR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1144748:KS2013 RS06170
gene id: 1144748:KS2013_RS06170
uniprot id: A0A1B3BAW7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1144748:KS2013 RS01145
gene id: 1144748:KS2013_RS01145
uniprot id: A0A1B3B833
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144748:KS2013 RS08470
gene id: 1144748:KS2013_RS08470
uniprot id: A0A1B3BC95
names: Similarity
messages: Belongs to the ArsC family.

1144748:KS2013 RS08245
gene id: 1144748:KS2013_RS08245
uniprot id: A0A1B3BC32
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1144748:KS2013 RS07140
gene id: 1144748:KS2013_RS07140
uniprot id: A0A1B3BBF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1144748:KS2013 RS02770
gene id: 1144748:KS2013_RS02770
uniprot id: A0A1B3B902
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1144748:KS2013 RS10010
gene id: 1144748:KS2013_RS10010
uniprot id: A0A1B3BCY6
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1144748:KS2013 RS01730
gene id: 1144748:KS2013_RS01730
uniprot id: A0A1B3B8E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

1144748:KS2013 RS05000
gene id: 1144748:KS2013_RS05000
uniprot id: A0A1B3BA69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1144748:KS2013 RS01710
gene id: 1144748:KS2013_RS01710
uniprot id: A0A1B3B8D9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1144748:KS2013 RS00510
gene id: 1144748:KS2013_RS00510
uniprot id: A0A1B3B7S0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1144748:KS2013 RS10375
gene id: 1144748:KS2013_RS10375
uniprot id: A0A1B3BD65
names: Similarity
messages: Belongs to the SfsA family.

1144748:KS2013 RS01440
gene id: 1144748:KS2013_RS01440
uniprot id: A0A1B3B896
names: Similarity
messages: Belongs to the HSP15 family.

1144748:KS2013 RS05610
gene id: 1144748:KS2013_RS05610
uniprot id: A0A1B3BAL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

1144748:KS2013 RS10610
gene id: 1144748:KS2013_RS10610
uniprot id: A0A1B3BDG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1144748:KS2013 RS08515
gene id: 1144748:KS2013_RS08515
uniprot id: A0A1B3BCB4
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1144748:KS2013 RS07435
gene id: 1144748:KS2013_RS07435
uniprot id: A0A1B3BBL2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1144748:KS2013 RS07930
gene id: 1144748:KS2013_RS07930
uniprot id: A0A1B3BBY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

1144748:KS2013 RS11035
gene id: 1144748:KS2013_RS11035
uniprot id: A0A1B3BDP2
names: Subcellular Location Annotation
messages: Membrane

1144748:KS2013 RS05490
gene id: 1144748:KS2013_RS05490
uniprot id: A0A1B3BAJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1144748:KS2013 RS03270
gene id: 1144748:KS2013_RS03270
uniprot id: A0A1B3B9B8
names: Subcellular Location Annotation
messages: Membrane

1144748:KS2013 RS09315
gene id: 1144748:KS2013_RS09315
uniprot id: A0A1B3BCN2
names: Subcellular Location Annotation
messages: Membrane

1144748:KS2013 RS02785
gene id: 1144748:KS2013_RS02785
uniprot id: A0A1B3B908
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1144748:KS2013 RS06355
gene id: 1144748:KS2013_RS06355
uniprot id: A0A1B3BB28
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

1144748:KS2013 RS02800
gene id: 1144748:KS2013_RS02800
uniprot id: A0A1B3B931
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

1144748:KS2013 RS07695
gene id: 1144748:KS2013_RS07695
uniprot id: A0A1B3BBR0
names: Subunit
messages: Heterodimer of HisH and HisF.

1144748:KS2013 RS09945
gene id: 1144748:KS2013_RS09945
uniprot id: A0A1B3BD05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1144748:KS2013 RS05160
gene id: 1144748:KS2013_RS05160
uniprot id: A0A1B3BAB2
names: Similarity
messages: Belongs to the UPF0339 family. Duplicated subfamily.

1144748:KS2013 RS01235
gene id: 1144748:KS2013_RS01235
uniprot id: A0A1B3B894
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1144748:KS2013 RS10035
gene id: 1144748:KS2013_RS10035
uniprot id: A0A1B3BD03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1144748:KS2013 RS01500
gene id: 1144748:KS2013_RS01500
uniprot id: A0A1B3B8A3
names: Similarity
messages: Belongs to the GSP N family.

1144748:KS2013 RS00590
gene id: 1144748:KS2013_RS00590
uniprot id: A0A1B3B7T1
names: Similarity
messages: Belongs to the peptidase S8 family.

1144748:KS2013 RS10560
gene id: 1144748:KS2013_RS10560
uniprot id: A0A1B3BDF7
names: Similarity
messages: Belongs to the PhoH family.

1144748:KS2013 RS07465
gene id: 1144748:KS2013_RS07465
uniprot id: A0A1B3BBL3
names: Subcellular Location Annotation
messages: Membrane

1144748:KS2013 RS01240
gene id: 1144748:KS2013_RS01240
uniprot id: A0A1B3B855
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1144748:KS2013 RS11000
gene id: 1144748:KS2013_RS11000
uniprot id: A0A1B3BDK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1144748:KS2013 RS02970
gene id: 1144748:KS2013_RS02970
uniprot id: A0A1B3B966
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1144748:KS2013 RS08325
gene id: 1144748:KS2013_RS08325
uniprot id: A0A1B3BC24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1144748:KS2013 RS08240
gene id: 1144748:KS2013_RS08240
uniprot id: A0A1B3BC10
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

1144748:KS2013 RS01485
gene id: 1144748:KS2013_RS01485
uniprot id: A0A1B3B8C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

1144748:KS2013 RS05200
gene id: 1144748:KS2013_RS05200
uniprot id: A0A1B3BAA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1144748:KS2013 RS01640
gene id: 1144748:KS2013_RS01640
uniprot id: A0A1B3B8H5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1144748:KS2013 RS06005
gene id: 1144748:KS2013_RS06005
uniprot id: A0A1B3BAT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1144748:KS2013 RS06055
gene id: 1144748:KS2013_RS06055
uniprot id: A0A1B3BAU4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1144748:KS2013 RS07075
gene id: 1144748:KS2013_RS07075
uniprot id: A0A1B3BBD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1144748:KS2013 RS07685
gene id: 1144748:KS2013_RS07685
uniprot id: A0A1B3BBR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1144748:KS2013 RS10855
gene id: 1144748:KS2013_RS10855
uniprot id: A0A1B3BDG6
names: Similarity
messages: Belongs to the GARS family.

1144748:KS2013 RS10015
gene id: 1144748:KS2013_RS10015
uniprot id: A0A1B3BD47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1144748:KS2013 RS10085
gene id: 1144748:KS2013_RS10085
uniprot id: A0A1B3BD12
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144748:KS2013 RS10485
gene id: 1144748:KS2013_RS10485
uniprot id: A0A1B3BDD3
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1144748:KS2013 RS10740
gene id: 1144748:KS2013_RS10740
uniprot id: A0A1B3BDI2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1144748:KS2013 RS06290
gene id: 1144748:KS2013_RS06290
uniprot id: A0A1B3BAY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

1144748:KS2013 RS04525
gene id: 1144748:KS2013_RS04525
uniprot id: A0A1B3B9Z5
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1144748:KS2013 RS02420
gene id: 1144748:KS2013_RS02420
uniprot id: A0A1B3B8V9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1144748:KS2013 RS09125
gene id: 1144748:KS2013_RS09125
uniprot id: A0A1B3BCH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

1144748:KS2013 RS02745
gene id: 1144748:KS2013_RS02745
uniprot id: A0A1B3B8Z4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1144748:KS2013 RS07770
gene id: 1144748:KS2013_RS07770
uniprot id: A0A1B3BBT3
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144748:KS2013 RS04495
gene id: 1144748:KS2013_RS04495
uniprot id: A0A1B3BA11
names: Similarity
messages: Belongs to the peptidase C40 family.

1144748:KS2013 RS03105
gene id: 1144748:KS2013_RS03105
uniprot id: A0A1B3B969
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1144748:KS2013 RS08345
gene id: 1144748:KS2013_RS08345
uniprot id: A0A1B3BC38
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.

1144748:KS2013 RS08180
gene id: 1144748:KS2013_RS08180
uniprot id: A0A1B3BC60
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1144748:KS2013 RS01555
gene id: 1144748:KS2013_RS01555
uniprot id: A0A1B3B8A7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein.

1144748:KS2013 RS08845
gene id: 1144748:KS2013_RS08845
uniprot id: A0A1B3BCB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1144748:KS2013 RS09890
gene id: 1144748:KS2013_RS09890
uniprot id: A0A1B3BCX4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1144748:KS2013 RS09960
gene id: 1144748:KS2013_RS09960
uniprot id: A0A1B3BCX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1144748:KS2013 RS03640
gene id: 1144748:KS2013_RS03640
uniprot id: A0A1B3B9H5
names: Subcellular Location Annotation
messages: Membrane

1144748:KS2013 RS03185
gene id: 1144748:KS2013_RS03185
uniprot id: A0A1B3B980
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

1144748:KS2013 RS08505
gene id: 1144748:KS2013_RS08505
uniprot id: A0A1B3BCB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1144748:KS2013 RS01065
gene id: 1144748:KS2013_RS01065
uniprot id: A0A1B3B819
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

1144748:KS2013 RS03675
gene id: 1144748:KS2013_RS03675
uniprot id: A0A1B3B9M2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144748:KS2013 RS02285
gene id: 1144748:KS2013_RS02285
uniprot id: A0A1B3B8R4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
messages: Cytoplasm
messages: Monomer.
messages: The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.

1144748:KS2013 RS06285
gene id: 1144748:KS2013_RS06285
uniprot id: A0A1B3BAZ3
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

1144748:KS2013 RS06630
gene id: 1144748:KS2013_RS06630
uniprot id: A0A1B3BB52
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

1144748:KS2013 RS06325
gene id: 1144748:KS2013_RS06325
uniprot id: A0A1B3BAZ9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1144748:KS2013 RS06545
gene id: 1144748:KS2013_RS06545
uniprot id: A0A1B3BB56
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1144748:KS2013 RS02825
gene id: 1144748:KS2013_RS02825
uniprot id: A0A1B3B937
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1144748:KS2013 RS01295
gene id: 1144748:KS2013_RS01295
uniprot id: A0A1B3B858
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1144748:KS2013 RS09080
gene id: 1144748:KS2013_RS09080
uniprot id: A0A1B3BCN6
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

1144748:KS2013 RS06095
gene id: 1144748:KS2013_RS06095
uniprot id: A0A1B3BAY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1144748:KS2013 RS09975
gene id: 1144748:KS2013_RS09975
uniprot id: A0A1B3BDC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1144748:KS2013 RS11265
gene id: 1144748:KS2013_RS11265
uniprot id: A0A1B3BDM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cytoplasm
messages: Sulfur carrier protein which probably makes part of a sulfur-relay system.

1144748:KS2013 RS07160
gene id: 1144748:KS2013_RS07160
uniprot id: A0A1B3BBF6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144748:KS2013 RS05820
gene id: 1144748:KS2013_RS05820
uniprot id: A0A1B3BAN9
names: Similarity
messages: Belongs to the UPF0434 family.

1144748:KS2013 RS02905
gene id: 1144748:KS2013_RS02905
uniprot id: A0A1B3B977
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1144748:KS2013 RS07525
gene id: 1144748:KS2013_RS07525
uniprot id: A0A1B3BBM9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1144748:KS2013 RS08910
gene id: 1144748:KS2013_RS08910
uniprot id: A0A1B3BCD4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1144748:KS2013 RS06350
gene id: 1144748:KS2013_RS06350
uniprot id: A0A1B3BAZ6
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1144748:KS2013 RS10265
gene id: 1144748:KS2013_RS10265
uniprot id: A0A1B3BD24
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1144748:KS2013 RS00780
gene id: 1144748:KS2013_RS00780
uniprot id: A0A1B3B7W5
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1144748:KS2013 RS05180
gene id: 1144748:KS2013_RS05180
uniprot id: A0A1B3BAH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1144748:KS2013 RS01990
gene id: 1144748:KS2013_RS01990
uniprot id: A0A1B3B8J2
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-71 and Arg-74) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

1144748:KS2013 RS09325
gene id: 1144748:KS2013_RS09325
uniprot id: A0A1B3BCL7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

1144748:KS2013 RS10295
gene id: 1144748:KS2013_RS10295
uniprot id: A0A1B3BD74
names: Similarity
messages: Belongs to the UPF0234 family.

1144748:KS2013 RS07170
gene id: 1144748:KS2013_RS07170
uniprot id: A0A1B3BBI2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1144748:KS2013 RS11445
gene id: 1144748:KS2013_RS11445
uniprot id: A0A1B3BDR2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

1144748:KS2013 RS08995
gene id: 1144748:KS2013_RS08995
uniprot id: A0A1B3BCF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1144748:KS2013 RS07955
gene id: 1144748:KS2013_RS07955
uniprot id: A0A1B3BBW1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1144748:KS2013 RS04775
gene id: 1144748:KS2013_RS04775
uniprot id: A0A1B3BA33
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

1144748:KS2013 RS03340
gene id: 1144748:KS2013_RS03340
uniprot id: A0A1B3B9B2
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1144748:KS2013 RS02895
gene id: 1144748:KS2013_RS02895
uniprot id: A0A1B3B928
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

1144748:KS2013 RS05770
gene id: 1144748:KS2013_RS05770
uniprot id: A0A1B3BAN2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1144748:KS2013 RS08090
gene id: 1144748:KS2013_RS08090
uniprot id: A0A1B3BBY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1144748:KS2013 RS04885
gene id: 1144748:KS2013_RS04885
uniprot id: A0A1B3BA54
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

1144748:KS2013 RS04925
gene id: 1144748:KS2013_RS04925
uniprot id: A0A1B3BA58
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1144748:KS2013 RS06115
gene id: 1144748:KS2013_RS06115
uniprot id: A0A1B3BAV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1144748:KS2013 RS08525
gene id: 1144748:KS2013_RS08525
uniprot id: A0A1B3BCD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1144748:KS2013 RS06160
gene id: 1144748:KS2013_RS06160
uniprot id: A0A1B3BAX3
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1144748:KS2013 RS09840
gene id: 1144748:KS2013_RS09840
uniprot id: A0A1B3BD22
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1144748:KS2013 RS10140
gene id: 1144748:KS2013_RS10140
uniprot id: A0A1B3BD64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

1144748:KS2013 RS10895
gene id: 1144748:KS2013_RS10895
uniprot id: A0A1B3BDJ4
names: Subcellular Location Annotation
messages: Membrane

1144748:KS2013 RS05510
gene id: 1144748:KS2013_RS05510
uniprot id: A0A1B3BAJ6
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1144748:KS2013 RS05485
gene id: 1144748:KS2013_RS05485
uniprot id: A0A1B3BAN1
names: Similarity
messages: Belongs to the fabD family.

1144748:KS2013 RS02750
gene id: 1144748:KS2013_RS02750
uniprot id: A0A1B3B922
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1144748:KS2013 RS01355
gene id: 1144748:KS2013_RS01355
uniprot id: A0A1B3B8A8
names: Similarity
messages: Belongs to the SCO1/2 family.

1144748:KS2013 RS03170
gene id: 1144748:KS2013_RS03170
uniprot id: A0A1B3B998
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1144748:KS2013 RS11655
gene id: 1144748:KS2013_RS11655
uniprot id: A0A1B3BDX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1144748:KS2013 RS08010
gene id: 1144748:KS2013_RS08010
uniprot id: A0A1B3BBZ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1144748:KS2013 RS00620
gene id: 1144748:KS2013_RS00620
uniprot id: A0A1B3B7T3
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1144748:KS2013 RS10820
gene id: 1144748:KS2013_RS10820
uniprot id: A0A1B3BDJ1
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1144748:KS2013 RS04750
gene id: 1144748:KS2013_RS04750
uniprot id: A0A1B3BA21
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144748:KS2013 RS08915
gene id: 1144748:KS2013_RS08915
uniprot id: A0A1B3BCI3
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

1144748:KS2013 RS04780
gene id: 1144748:KS2013_RS04780
uniprot id: A0A1B3BA70
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1144748:KS2013 RS10240
gene id: 1144748:KS2013_RS10240
uniprot id: A0A1B3BD33
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1144748:KS2013 RS06570
gene id: 1144748:KS2013_RS06570
uniprot id: A0A1B3BB38
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1144748:KS2013 RS10815
gene id: 1144748:KS2013_RS10815
uniprot id: A0A1B3BDD2
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1144748:KS2013 RS11710
gene id: 1144748:KS2013_RS11710
uniprot id: A0A1B3BE25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1144748:KS2013 RS05720
gene id: 1144748:KS2013_RS05720
uniprot id: A0A1B3BAM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopD family.
messages: Cell inner membrane
messages: Involved in copper resistance. Appears to be involved in copper uptake.
messages: Membrane

1144748:KS2013 RS04950
gene id: 1144748:KS2013_RS04950
uniprot id: A0A1B3BA55
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

1144748:KS2013 RS08940
gene id: 1144748:KS2013_RS08940
uniprot id: A0A1B3BCE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1144748:KS2013 RS10790
gene id: 1144748:KS2013_RS10790
uniprot id: A0A1B3BDD4
names: Similarity
messages: Belongs to the CutA family.

1144748:KS2013 RS00675
gene id: 1144748:KS2013_RS00675
uniprot id: A0A1B3B7W3
names: Function
names: Similarity
messages: Belongs to the peptidase C56 family.
messages: Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate.

1144748:KS2013 RS01475
gene id: 1144748:KS2013_RS01475
uniprot id: A0A1B3B8A0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

1144748:KS2013 RS02725
gene id: 1144748:KS2013_RS02725
uniprot id: A0A1B3B921
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1144748:KS2013 RS05875
gene id: 1144748:KS2013_RS05875
uniprot id: A0A1B3BAT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

1144748:KS2013 RS09645
gene id: 1144748:KS2013_RS09645
uniprot id: A0A1B3BCY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1144748:KS2013 RS09680
gene id: 1144748:KS2013_RS09680
uniprot id: A0A1B3BCX8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144748:KS2013 RS01285
gene id: 1144748:KS2013_RS01285
uniprot id: A0A1B3B863
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1144748:KS2013 RS11720
gene id: 1144748:KS2013_RS11720
uniprot id: A0A1B3BE67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1144748:KS2013 RS08745
gene id: 1144748:KS2013_RS08745
uniprot id: A0A1B3BCA3
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1144748:KS2013 RS01875
gene id: 1144748:KS2013_RS01875
uniprot id: A0A1B3B8H3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144748:KS2013 RS09240
gene id: 1144748:KS2013_RS09240
uniprot id: A0A1B3BCS2
names: Similarity
messages: Belongs to the DEAD box helicase family.

1144748:KS2013 RS08340
gene id: 1144748:KS2013_RS08340
uniprot id: A0A1B3BC23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1144748:KS2013 RS03755
gene id: 1144748:KS2013_RS03755
uniprot id: A0A1B3B9J1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144748:KS2013 RS01345
gene id: 1144748:KS2013_RS01345
uniprot id: A0A1B3B866
names: Subcellular Location Annotation
messages: Membrane

1144748:KS2013 RS05680
gene id: 1144748:KS2013_RS05680
uniprot id: A0A1B3BAN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

1144748:KS2013 RS03500
gene id: 1144748:KS2013_RS03500
uniprot id: A0A1B3B9E9
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

1144748:KS2013 RS10060
gene id: 1144748:KS2013_RS10060
uniprot id: A0A1B3BCZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1144748:KS2013 RS09575
gene id: 1144748:KS2013_RS09575
uniprot id: A0A1B3BCQ8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

1144748:KS2013 RS10620
gene id: 1144748:KS2013_RS10620
uniprot id: A0A1B3BDE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1144748:KS2013 RS02435
gene id: 1144748:KS2013_RS02435
uniprot id: A0A1B3B8U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

1144748:KS2013 RS01900
gene id: 1144748:KS2013_RS01900
uniprot id: A0A1B3B8J0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1144748:KS2013 RS03860
gene id: 1144748:KS2013_RS03860
uniprot id: A0A1B3B9L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1144748:KS2013 RS10350
gene id: 1144748:KS2013_RS10350
uniprot id: A0A1B3BD71
names: Similarity
messages: Belongs to the peptidase M17 family.

1144748:KS2013 RS10675
gene id: 1144748:KS2013_RS10675
uniprot id: A0A1B3BDG3
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1144748:KS2013 RS11680
gene id: 1144748:KS2013_RS11680
uniprot id: A0A1B3BE85
names: Subcellular Location Annotation
messages: Periplasm

1144748:KS2013 RS03840
gene id: 1144748:KS2013_RS03840
uniprot id: A0A1B3B9P5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

1144748:KS2013 RS06465
gene id: 1144748:KS2013_RS06465
uniprot id: A0A1B3BB18
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144748:KS2013 RS05595
gene id: 1144748:KS2013_RS05595
uniprot id: A0A1B3BAJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1144748:KS2013 RS09190
gene id: 1144748:KS2013_RS09190
uniprot id: A0A1B3BCQ1
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1144748:KS2013 RS09030
gene id: 1144748:KS2013_RS09030
uniprot id: A0A1B3BCM7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144748:KS2013 RS09040
gene id: 1144748:KS2013_RS09040
uniprot id: A0A1B3BCG4
names: Subcellular Location Annotation
messages: Membrane

1144748:KS2013 RS05760
gene id: 1144748:KS2013_RS05760
uniprot id: A0A1B3BAQ7
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

1144748:KS2013 RS07095
gene id: 1144748:KS2013_RS07095
uniprot id: A0A1B3BBE1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Monomer.

1144748:KS2013 RS01350
gene id: 1144748:KS2013_RS01350
uniprot id: A0A1B3B893
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1144748:KS2013 RS07115
gene id: 1144748:KS2013_RS07115
uniprot id: A0A1B3BBF4
names: Similarity
messages: Belongs to the DnaA family.

1144748:KS2013 RS05330
gene id: 1144748:KS2013_RS05330
uniprot id: A0A1B3BAE2
names: Similarity
messages: Belongs to the asparaginase 1 family.

1144748:KS2013 RS06250
gene id: 1144748:KS2013_RS06250
uniprot id: A0A1B3BB12
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1144748:KS2013 RS07310
gene id: 1144748:KS2013_RS07310
uniprot id: A0A1B3BBI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1144748:KS2013 RS07180
gene id: 1144748:KS2013_RS07180
uniprot id: A0A1B3BBG5
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

1144748:KS2013 RS01680
gene id: 1144748:KS2013_RS01680
uniprot id: A0A1B3B8D6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1144748:KS2013 RS01265
gene id: 1144748:KS2013_RS01265
uniprot id: A0A1B3B862
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

1144748:KS2013 RS01290
gene id: 1144748:KS2013_RS01290
uniprot id: A0A1B3B865
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1144748:KS2013 RS07710
gene id: 1144748:KS2013_RS07710
uniprot id: A0A1B3BBR5
names: Function
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.

1144748:KS2013 RS09225
gene id: 1144748:KS2013_RS09225
uniprot id: A0A1B3BCJ5
names: Similarity
messages: Belongs to the MipA/OmpV family.

1144748:KS2013 RS04535
gene id: 1144748:KS2013_RS04535
uniprot id: A0A1B3BA03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

1144748:KS2013 RS10395
gene id: 1144748:KS2013_RS10395
uniprot id: A0A1B3BD91
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1144748:KS2013 RS10850
gene id: 1144748:KS2013_RS10850
uniprot id: A0A1B3BDH6
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1144748:KS2013 RS11570
gene id: 1144748:KS2013_RS11570
uniprot id: A0A1B3BDS8
names: Similarity
messages: Belongs to the thioredoxin family.

1144748:KS2013 RS08015
gene id: 1144748:KS2013_RS08015
uniprot id: A0A1B3BBW9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1144748:KS2013 RS09150
gene id: 1144748:KS2013_RS09150
uniprot id: A0A1B3BCI7
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1144748:KS2013 RS06995
gene id: 1144748:KS2013_RS06995
uniprot id: A0A1B3BBC1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1144748:KS2013 RS10795
gene id: 1144748:KS2013_RS10795
uniprot id: A0A1B3BDG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

1144748:KS2013 RS09085
gene id: 1144748:KS2013_RS09085
uniprot id: A0A1B3BCL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1144748:KS2013 RS03060
gene id: 1144748:KS2013_RS03060
uniprot id: A0A1B3B963
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1144748:KS2013 RS01495
gene id: 1144748:KS2013_RS01495
uniprot id: A0A1B3B8A6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP M family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

1144748:KS2013 RS05260
gene id: 1144748:KS2013_RS05260
uniprot id: A0A1B3BAB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

1144748:KS2013 RS08835
gene id: 1144748:KS2013_RS08835
uniprot id: A0A1B3BCC5
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1144748:KS2013 RS00040
gene id: 1144748:KS2013_RS00040
uniprot id: A0A1B3B7H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

1144748:KS2013 RS04265
gene id: 1144748:KS2013_RS04265
uniprot id: A0A1B3B9T8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

1144748:KS2013 RS02280
gene id: 1144748:KS2013_RS02280
uniprot id: A0A1B3B8Q8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

1144748:KS2013 RS00150
gene id: 1144748:KS2013_RS00150
uniprot id: A0A1B3B7K2
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1144748:KS2013 RS04545
gene id: 1144748:KS2013_RS04545
uniprot id: A0A1B3BA25
names: Similarity
messages: Belongs to the DsrF/TusC family.

1144748:KS2013 RS11155
gene id: 1144748:KS2013_RS11155
uniprot id: A0A1B3BDM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1144748:KS2013 RS06450
gene id: 1144748:KS2013_RS06450
uniprot id: A0A1B3BB21
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1144748:KS2013 RS10735
gene id: 1144748:KS2013_RS10735
uniprot id: A0A1B3BDQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1144748:KS2013 RS09305
gene id: 1144748:KS2013_RS09305
uniprot id: A0A1B3BCL1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

1144748:KS2013 RS01165
gene id: 1144748:KS2013_RS01165
uniprot id: A0A1B3B839
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.

1144748:KS2013 RS09270
gene id: 1144748:KS2013_RS09270
uniprot id: A0A1B3BCQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
messages: Monomer.

1144748:KS2013 RS09695
gene id: 1144748:KS2013_RS09695
uniprot id: A0A1B3BCZ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1144748:KS2013 RS05190
gene id: 1144748:KS2013_RS05190
uniprot id: A0A1B3BAE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1144748:KS2013 RS09285
gene id: 1144748:KS2013_RS09285
uniprot id: A0A1B3BCK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1144748:KS2013 RS05675
gene id: 1144748:KS2013_RS05675
uniprot id: A0A1B3BAQ0
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

1144748:KS2013 RS08865
gene id: 1144748:KS2013_RS08865
uniprot id: A0A1B3BCH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

1144748:KS2013 RS09985
gene id: 1144748:KS2013_RS09985
uniprot id: A0A1B3BCZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1144748:KS2013 RS00595
gene id: 1144748:KS2013_RS00595
uniprot id: A0A1B3B7S9
names: Similarity
messages: Belongs to the peptidase S8 family.

1144748:KS2013 RS08795
gene id: 1144748:KS2013_RS08795
uniprot id: A0A1B3BCA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

1144748:KS2013 RS09915
gene id: 1144748:KS2013_RS09915
uniprot id: A0A1B3BD26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1144748:KS2013 RS02330
gene id: 1144748:KS2013_RS02330
uniprot id: A0A1B3B8S1
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

1144748:KS2013 RS01275
gene id: 1144748:KS2013_RS01275
uniprot id: A0A1B3B880
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1144748:KS2013 RS02385
gene id: 1144748:KS2013_RS02385
uniprot id: A0A1B3B8T4
names: Function
names: Subunit
messages: Homotetramer.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1144748:KS2013 RS07195
gene id: 1144748:KS2013_RS07195
uniprot id: A0A1B3BBI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiV subfamily.
messages: Forms an heterodimer with UbiU.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiU, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

1144748:KS2013 RS10665
gene id: 1144748:KS2013_RS10665
uniprot id: A0A1B3BDH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1144748:KS2013 RS11575
gene id: 1144748:KS2013_RS11575
uniprot id: A0A1B3BE36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

1144748:KS2013 RS02115
gene id: 1144748:KS2013_RS02115
uniprot id: A0A1B3B8L5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

1144748:KS2013 RS02555
gene id: 1144748:KS2013_RS02555
uniprot id: A0A1B3B8W0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1144748:KS2013 RS05810
gene id: 1144748:KS2013_RS05810
uniprot id: A0A1B3BAR2
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1144748:KS2013 RS05415
gene id: 1144748:KS2013_RS05415
uniprot id: A0A1B3BAG3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

1144748:KS2013 RS09800
gene id: 1144748:KS2013_RS09800
uniprot id: A0A1B3BCY3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

1144748:KS2013 RS10380
gene id: 1144748:KS2013_RS10380
uniprot id: A0A1B3BDJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

1144748:KS2013 RS09140
gene id: 1144748:KS2013_RS09140
uniprot id: A0A1B3BCI6
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1144748:KS2013 RS03395
gene id: 1144748:KS2013_RS03395
uniprot id: A0A1B3B9D6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1144748:KS2013 RS07700
gene id: 1144748:KS2013_RS07700
uniprot id: A0A1B3BBR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1144748:KS2013 RS03225
gene id: 1144748:KS2013_RS03225
uniprot id: A0A1B3B9D7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

1144748:KS2013 RS07400
gene id: 1144748:KS2013_RS07400
uniprot id: A0A1B3BBL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

1144748:KS2013 RS03710
gene id: 1144748:KS2013_RS03710
uniprot id: A0A1B3B9I5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1144748:KS2013 RS03250
gene id: 1144748:KS2013_RS03250
uniprot id: A0A1B3B9A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1144748:KS2013 RS07765
gene id: 1144748:KS2013_RS07765
uniprot id: A0A1B3BBS3
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1144748:KS2013 RS00495
gene id: 1144748:KS2013_RS00495
uniprot id: A0A1B3B7R4
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

1144748:KS2013 RS00980
gene id: 1144748:KS2013_RS00980
uniprot id: A0A1B3B803
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

1144748:KS2013 RS06110
gene id: 1144748:KS2013_RS06110
uniprot id: A0A1B3BAW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1144748:KS2013 RS08315
gene id: 1144748:KS2013_RS08315
uniprot id: A0A1B3BC36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1144748:KS2013 RS02225
gene id: 1144748:KS2013_RS02225
uniprot id: A0A1B3B8S3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

1144748:KS2013 RS05700
gene id: 1144748:KS2013_RS05700
uniprot id: A0A1B3BAM5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1144748:KS2013 RS10650
gene id: 1144748:KS2013_RS10650
uniprot id: A0A1B3BDE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1144748:KS2013 RS09850
gene id: 1144748:KS2013_RS09850
uniprot id: A0A1B3BCZ1
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1144748:KS2013 RS01675
gene id: 1144748:KS2013_RS01675
uniprot id: A0A1B3B8D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

1144748:KS2013 RS10415
gene id: 1144748:KS2013_RS10415
uniprot id: A0A1B3BD49
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144748:KS2013 RS00485
gene id: 1144748:KS2013_RS00485
uniprot id: A0A1B3B7R3
names: Subcellular Location Annotation
messages: Membrane

1144748:KS2013 RS00955
gene id: 1144748:KS2013_RS00955
uniprot id: A0A1B3B7Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1144748:KS2013 RS04770
gene id: 1144748:KS2013_RS04770
uniprot id: A0A1B3BAA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

1144748:KS2013 RS07250
gene id: 1144748:KS2013_RS07250
uniprot id: A0A1B3BBI7
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1144748:KS2013 RS01850
gene id: 1144748:KS2013_RS01850
uniprot id: A0A1B3B8I0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144748:KS2013 RS08495
gene id: 1144748:KS2013_RS08495
uniprot id: A0A1B3BC58
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1144748:KS2013 RS01585
gene id: 1144748:KS2013_RS01585
uniprot id: A0A1B3B8E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1144748:KS2013 RS07980
gene id: 1144748:KS2013_RS07980
uniprot id: A0A1B3BBZ5
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1144748:KS2013 RS00015
gene id: 1144748:KS2013_RS00015
uniprot id: A0A1B3B7H1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1144748:KS2013 RS08755
gene id: 1144748:KS2013_RS08755
uniprot id: A0A1B3BCG7
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1144748:KS2013 RS06935
gene id: 1144748:KS2013_RS06935
uniprot id: A0A1B3BBB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1144748:KS2013 RS09000
gene id: 1144748:KS2013_RS09000
uniprot id: A0A1B3BCF1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1144748:KS2013 RS05390
gene id: 1144748:KS2013_RS05390
uniprot id: A0A1B3BAG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

1144748:KS2013 RS06045
gene id: 1144748:KS2013_RS06045
uniprot id: A0A1B3BAX1
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1144748:KS2013 RS03915
gene id: 1144748:KS2013_RS03915
uniprot id: A0A1B3B9P8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1144748:KS2013 RS09450
gene id: 1144748:KS2013_RS09450
uniprot id: A0A1B3BCN8
names: Similarity
messages: Belongs to the Gfa family.

1144748:KS2013 RS10605
gene id: 1144748:KS2013_RS10605
uniprot id: A0A1B3BDA8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1144748:KS2013 RS03035
gene id: 1144748:KS2013_RS03035
uniprot id: A0A1B3B956
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1144748:KS2013 RS06955
gene id: 1144748:KS2013_RS06955
uniprot id: A0A1B3BBC3
names: Similarity
messages: Belongs to the anthranilate synthase component I family.

1144748:KS2013 RS11735
gene id: 1144748:KS2013_RS11735
uniprot id: A0A1B3BE30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1144748:KS2013 RS11105
gene id: 1144748:KS2013_RS11105
uniprot id: A0A1B3BDL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1144748:KS2013 RS10680
gene id: 1144748:KS2013_RS10680
uniprot id: A0A1B3BDC1
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1144748:KS2013 RS00445
gene id: 1144748:KS2013_RS00445
uniprot id: A0A1B3B7Q5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1144748:KS2013 RS05665
gene id: 1144748:KS2013_RS05665
uniprot id: A0A1B3BAL3
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

1144748:KS2013 RS06785
gene id: 1144748:KS2013_RS06785
uniprot id: A0A1B3BB83
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

1144748:KS2013 RS03610
gene id: 1144748:KS2013_RS03610
uniprot id: A0A1B3B9G2
names: Function
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1144748:KS2013 RS10720
gene id: 1144748:KS2013_RS10720
uniprot id: A0A1B3BDB5
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

1144748:KS2013 RS09905
gene id: 1144748:KS2013_RS09905
uniprot id: A0A1B3BCZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1144748:KS2013 RS05590
gene id: 1144748:KS2013_RS05590
uniprot id: A0A1B3BAL5
names: Similarity
messages: Belongs to the peptidase S41A family.

1144748:KS2013 RS08290
gene id: 1144748:KS2013_RS08290
uniprot id: A0A1B3BC15
names: Subcellular Location Annotation
messages: Cytoplasm

1144748:KS2013 RS02485
gene id: 1144748:KS2013_RS02485
uniprot id: A0A1B3B8V4
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

1144748:KS2013 RS00575
gene id: 1144748:KS2013_RS00575
uniprot id: A0A1B3B7T8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1144748:KS2013 RS08350
gene id: 1144748:KS2013_RS08350
uniprot id: A0A1B3BC33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1144748:KS2013 RS10700
gene id: 1144748:KS2013_RS10700
uniprot id: A0A1B3BDF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1144748:KS2013 RS03560
gene id: 1144748:KS2013_RS03560
uniprot id: A0A1B3B9F3
names: Similarity
messages: Belongs to the SlyX family.

1144748:KS2013 RS08785
gene id: 1144748:KS2013_RS08785
uniprot id: A0A1B3BCB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

1144748:KS2013 RS08855
gene id: 1144748:KS2013_RS08855
uniprot id: A0A1B3BCI1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1144748:KS2013 RS01010
gene id: 1144748:KS2013_RS01010
uniprot id: A0A1B3B836
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1144748:KS2013 RS06760
gene id: 1144748:KS2013_RS06760
uniprot id: A0A1B3BBA2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144748:KS2013 RS06780
gene id: 1144748:KS2013_RS06780
uniprot id: A0A1B3BB74
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1144748:KS2013 RS10080
gene id: 1144748:KS2013_RS10080
uniprot id: A0A1B3BD70
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1144748:KS2013 RS07735
gene id: 1144748:KS2013_RS07735
uniprot id: A0A1B3BBS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1144748:KS2013 RS07935
gene id: 1144748:KS2013_RS07935
uniprot id: A0A1B3BBV8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1144748:KS2013 RS04340
gene id: 1144748:KS2013_RS04340
uniprot id: A0A1B3B9W0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1144748:KS2013 RS00615
gene id: 1144748:KS2013_RS00615
uniprot id: A0A1B3B7T7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

1144748:KS2013 RS08330
gene id: 1144748:KS2013_RS08330
uniprot id: A0A1B3BC98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1144748:KS2013 RS08320
gene id: 1144748:KS2013_RS08320
uniprot id: A0A1B3BC69
names: Similarity
messages: Belongs to the skp family.

1144748:KS2013 RS06100
gene id: 1144748:KS2013_RS06100
uniprot id: A0A1B3BAV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

1144748:KS2013 RS00545
gene id: 1144748:KS2013_RS00545
uniprot id: A0A1B3B7R8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

1144748:KS2013 RS01575
gene id: 1144748:KS2013_RS01575
uniprot id: A0A1B3B8B9
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

1144748:KS2013 RS08535
gene id: 1144748:KS2013_RS08535
uniprot id: A0A1B3BC63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1144748:KS2013 RS00795
gene id: 1144748:KS2013_RS00795
uniprot id: A0A1B3B7X2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1144748:KS2013 RS02260
gene id: 1144748:KS2013_RS02260
uniprot id: A0A1B3B8P5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1144748:KS2013 RS02345
gene id: 1144748:KS2013_RS02345
uniprot id: A0A1B3B8T8
names: Function
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

1144748:KS2013 RS10670
gene id: 1144748:KS2013_RS10670
uniprot id: A0A1B3BDA2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1144748:KS2013 RS05500
gene id: 1144748:KS2013_RS05500
uniprot id: A0A1B3BAI4
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1144748:KS2013 RS07415
gene id: 1144748:KS2013_RS07415
uniprot id: A0A1B3BBK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

1144748:KS2013 RS02355
gene id: 1144748:KS2013_RS02355
uniprot id: A0A1B3B8S2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1144748:KS2013 RS07385
gene id: 1144748:KS2013_RS07385
uniprot id: A0A1B3BBK2
names: Subcellular Location Annotation
messages: Membrane

1144748:KS2013 RS10075
gene id: 1144748:KS2013_RS10075
uniprot id: A0A1B3BDE5
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1144748:KS2013 RS06230
gene id: 1144748:KS2013_RS06230
uniprot id: A0A1B3BAY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
messages: Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
messages: Homotetramer.

1144748:KS2013 RS05600
gene id: 1144748:KS2013_RS05600
uniprot id: A0A1B3BAK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1144748:KS2013 RS07425
gene id: 1144748:KS2013_RS07425
uniprot id: A0A1B3BBM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BexD/CtrA/VexA family.
messages: Cell outer membrane
messages: Membrane

1144748:KS2013 RS02830
gene id: 1144748:KS2013_RS02830
uniprot id: A0A1B3B933
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1144748:KS2013 RS04825
gene id: 1144748:KS2013_RS04825
uniprot id: A0A1B3BA43
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

1144748:KS2013 RS08055
gene id: 1144748:KS2013_RS08055
uniprot id: A0A1B3BBY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

1144748:KS2013 RS11540
gene id: 1144748:KS2013_RS11540
uniprot id: A0A1B3BDZ3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1144748:KS2013 RS00800
gene id: 1144748:KS2013_RS00800
uniprot id: A0A1B3B7X0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1144748:KS2013 RS04270
gene id: 1144748:KS2013_RS04270
uniprot id: A0A1B3B9T7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

1144748:KS2013 RS07630
gene id: 1144748:KS2013_RS07630
uniprot id: A0A1B3BBQ9
names: Similarity
messages: Belongs to the BolA/IbaG family.

1144748:KS2013 RS11300
gene id: 1144748:KS2013_RS11300
uniprot id: A0A1B3BDR6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1144748:KS2013 RS06525
gene id: 1144748:KS2013_RS06525
uniprot id: A0A1B3BB31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1144748:KS2013 RS06125
gene id: 1144748:KS2013_RS06125
uniprot id: A0A1B3BAV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

1144748:KS2013 RS11095
gene id: 1144748:KS2013_RS11095
uniprot id: A0A1B3BDI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1144748:KS2013 RS09120
gene id: 1144748:KS2013_RS09120
uniprot id: A0A1B3BCM0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1144748:KS2013 RS09185
gene id: 1144748:KS2013_RS09185
uniprot id: A0A1B3BCQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1144748:KS2013 RS11005
gene id: 1144748:KS2013_RS11005
uniprot id: A0A1B3BDI9
names: Similarity
messages: Belongs to the YggT family.

1144748:KS2013 RS08880
gene id: 1144748:KS2013_RS08880
uniprot id: A0A1B3BCE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1144748:KS2013 RS01610
gene id: 1144748:KS2013_RS01610
uniprot id: A0A1B3B8E4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

1144748:KS2013 RS06505
gene id: 1144748:KS2013_RS06505
uniprot id: A0A1B3BB29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1144748:KS2013 RS02170
gene id: 1144748:KS2013_RS02170
uniprot id: A0A1B3B8M9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1144748:KS2013 RS11760
gene id: 1144748:KS2013_RS11760
uniprot id: A0A1B3BE35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1144748:KS2013 RS09410
gene id: 1144748:KS2013_RS09410
uniprot id: A0A1B3BCN0
names: Similarity
messages: Belongs to the UPF0047 family.

1144748:KS2013 RS01685
gene id: 1144748:KS2013_RS01685
uniprot id: A0A1B3B8D3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1144748:KS2013 RS10595
gene id: 1144748:KS2013_RS10595
uniprot id: A0A1B3BDD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1144748:KS2013 RS08720
gene id: 1144748:KS2013_RS08720
uniprot id: A0A1B3BC91
names: Similarity
messages: Belongs to the peptidase M13 family.

1144748:KS2013 RS01100
gene id: 1144748:KS2013_RS01100
uniprot id: A0A1B3B831
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1144748:KS2013 RS10645
gene id: 1144748:KS2013_RS10645
uniprot id: A0A1B3BDA5
names: Subcellular Location Annotation
messages: Membrane

1144748:KS2013 RS11145
gene id: 1144748:KS2013_RS11145
uniprot id: A0A1B3BDK5
names: Similarity
messages: Belongs to the glutamate synthase family.

1144748:KS2013 RS06455
gene id: 1144748:KS2013_RS06455
uniprot id: A0A1B3BB13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1144748:KS2013 RS02405
gene id: 1144748:KS2013_RS02405
uniprot id: A0A1B3B8S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1144748:KS2013 RS08355
gene id: 1144748:KS2013_RS08355
uniprot id: A0A1B3BC28
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144748:KS2013 RS04240
gene id: 1144748:KS2013_RS04240
uniprot id: A0A1B3B9U1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1144748:KS2013 RS04075
gene id: 1144748:KS2013_RS04075
uniprot id: A0A1B3B9P7
names: Similarity
messages: Belongs to the peptidase S8 family.

1144748:KS2013 RS02010
gene id: 1144748:KS2013_RS02010
uniprot id: A0A1B3B8K1
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1144748:KS2013 RS09560
gene id: 1144748:KS2013_RS09560
uniprot id: A0A1B3BCR4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

1144748:KS2013 RS03645
gene id: 1144748:KS2013_RS03645
uniprot id: A0A1B3B9I8
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1144748:KS2013 RS11745
gene id: 1144748:KS2013_RS11745
uniprot id: A0A1B3BE03
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

1144748:KS2013 RS00265
gene id: 1144748:KS2013_RS00265
uniprot id: A0A1B3B7M7
names: Similarity
messages: Belongs to the YkuD family.

1144748:KS2013 RS08980
gene id: 1144748:KS2013_RS08980
uniprot id: A0A1B3BCL5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1144748:KS2013 RS06675
gene id: 1144748:KS2013_RS06675
uniprot id: A0A1B3BB66
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1144748:KS2013 RS04490
gene id: 1144748:KS2013_RS04490
uniprot id: A0A1B3B9Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

1144748:KS2013 RS06945
gene id: 1144748:KS2013_RS06945
uniprot id: A0A1B3BBA9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144748:KS2013 RS10885
gene id: 1144748:KS2013_RS10885
uniprot id: A0A1B3BDL3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

1144748:KS2013 RS02110
gene id: 1144748:KS2013_RS02110
uniprot id: A0A1B3B8M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

1144748:KS2013 RS03540
gene id: 1144748:KS2013_RS03540
uniprot id: A0A1B3B9F5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1144748:KS2013 RS03905
gene id: 1144748:KS2013_RS03905
uniprot id: A0A1B3B9M6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1144748:KS2013 RS05830
gene id: 1144748:KS2013_RS05830
uniprot id: A0A1B3BAQ9
names: Subcellular Location Annotation
messages: Membrane

1144748:KS2013 RS04760
gene id: 1144748:KS2013_RS04760
uniprot id: A0A1B3BA90
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

1144748:KS2013 RS10840
gene id: 1144748:KS2013_RS10840
uniprot id: A0A1B3BDE4
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1144748:KS2013 RS02175
gene id: 1144748:KS2013_RS02175
uniprot id: A0A1B3B8R3
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

1144748:KS2013 RS03175
gene id: 1144748:KS2013_RS03175
uniprot id: A0A1B3B9D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1144748:KS2013 RS10455
gene id: 1144748:KS2013_RS10455
uniprot id: A0A1B3BD86
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1144748:KS2013 RS08750
gene id: 1144748:KS2013_RS08750
uniprot id: A0A1B3BCC7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1144748:KS2013 RS09230
gene id: 1144748:KS2013_RS09230
uniprot id: A0A1B3BCQ2
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1144748:KS2013 RS08820
gene id: 1144748:KS2013_RS08820
uniprot id: A0A1B3BCC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1144748:KS2013 RS08060
gene id: 1144748:KS2013_RS08060
uniprot id: A0A1B3BC02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1144748:KS2013 RS01755
gene id: 1144748:KS2013_RS01755
uniprot id: A0A1B3B8E9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1144748:KS2013 RS05740
gene id: 1144748:KS2013_RS05740
uniprot id: A0A1B3BAP4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1144748:KS2013 RS10545
gene id: 1144748:KS2013_RS10545
uniprot id: A0A1B3BDB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1144748:KS2013 RS00350
gene id: 1144748:KS2013_RS00350
uniprot id: A0A1B3B7N8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1144748:KS2013 RS06140
gene id: 1144748:KS2013_RS06140
uniprot id: A0A1B3BAV3
names: Function
messages: Mediates the mercuric-dependent induction of mercury resistance operon. In the absence of mercury MerR represses transcription by binding tightly to the mer operator region; when mercury is present the dimeric complex binds a single ion and becomes a potent transcriptional activator, while remaining bound to the mer site.

1144748:KS2013 RS00685
gene id: 1144748:KS2013_RS00685
uniprot id: A0A1B3B7V5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1144748:KS2013 RS06030
gene id: 1144748:KS2013_RS06030
uniprot id: A0A1B3BAT3
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

1144748:KS2013 RS09925
gene id: 1144748:KS2013_RS09925
uniprot id: A0A1B3BDB6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1144748:KS2013 RS00935
gene id: 1144748:KS2013_RS00935
uniprot id: A0A1B3B7Z7
names: Caution
names: Function
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144748:KS2013 RS00065
gene id: 1144748:KS2013_RS00065
uniprot id: A0A1B3B7I0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1144748:KS2013 RS01835
gene id: 1144748:KS2013_RS01835
uniprot id: A0A1B3B8G2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1144748:KS2013 RS03465
gene id: 1144748:KS2013_RS03465
uniprot id: A0A1B3B9C9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: In the C-terminal section; belongs to the transglycosylase Slt family.
messages: In the N-terminal section; belongs to the bacterial solute-binding protein 3 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
messages: The N-terminal domain does not have lytic activity and probably modulates enzymatic activity. The C-terminal domain is the catalytic active domain.

1144748:KS2013 RS04895
gene id: 1144748:KS2013_RS04895
uniprot id: A0A1B3BA56
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

1144748:KS2013 RS05585
gene id: 1144748:KS2013_RS05585
uniprot id: A0A1B3BAN7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1144748:KS2013 RS11610
gene id: 1144748:KS2013_RS11610
uniprot id: A0A1B3BDW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

1144748:KS2013 RS01250
gene id: 1144748:KS2013_RS01250
uniprot id: A0A1B3B848
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1144748:KS2013 RS01280
gene id: 1144748:KS2013_RS01280
uniprot id: A0A1B3B8A5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1144748:KS2013 RS04220
gene id: 1144748:KS2013_RS04220
uniprot id: A0A1B3B9S7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144748:KS2013 RS09165
gene id: 1144748:KS2013_RS09165
uniprot id: A0A1B3BCI5
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1144748:KS2013 RS05080
gene id: 1144748:KS2013_RS05080
uniprot id: A0A1B3BAC8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144748:KS2013 RS07230
gene id: 1144748:KS2013_RS07230
uniprot id: A0A1B3BBH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1144748:KS2013 RS09265
gene id: 1144748:KS2013_RS09265
uniprot id: A0A1B3BCM4
names: Similarity
messages: Belongs to the CFA/CMAS family.

1144748:KS2013 RS04345
gene id: 1144748:KS2013_RS04345
uniprot id: A0A1B3B9Y1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

1144748:KS2013 RS09690
gene id: 1144748:KS2013_RS09690
uniprot id: A0A1B3BD25
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.