1144275:COCOR RS00005
gene id: 1144275:COCOR_RS00005
uniprot id: H8MRW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1144275:COCOR RS25920
gene id: 1144275:COCOR_RS25920
uniprot id: H8MSU4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS40175
gene id: 1144275:COCOR_RS40175
uniprot id: H8MZL2
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS32935
gene id: 1144275:COCOR_RS32935
uniprot id: H8MW48
names: Similarity
messages: Belongs to the TrpF family.

1144275:COCOR RS00690
gene id: 1144275:COCOR_RS00690
uniprot id: H8MV04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1144275:COCOR RS17090
gene id: 1144275:COCOR_RS17090
uniprot id: H8MJA6
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

1144275:COCOR RS39360
gene id: 1144275:COCOR_RS39360
uniprot id: H8MWD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1144275:COCOR RS26690
gene id: 1144275:COCOR_RS26690
uniprot id: H8MW01
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

1144275:COCOR RS36000
gene id: 1144275:COCOR_RS36000
uniprot id: H8MIM1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

1144275:COCOR RS32350
gene id: 1144275:COCOR_RS32350
uniprot id: H8MT27
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1144275:COCOR RS15185
gene id: 1144275:COCOR_RS15185
uniprot id: H8N1M1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1144275:COCOR RS07730
gene id: 1144275:COCOR_RS07730
uniprot id: H8MWX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1144275:COCOR RS15210
gene id: 1144275:COCOR_RS15210
uniprot id: H8N1M6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1144275:COCOR RS10495
gene id: 1144275:COCOR_RS10495
uniprot id: H8MJ07
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1144275:COCOR RS09950
gene id: 1144275:COCOR_RS09950
uniprot id: H8MHK4
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1144275:COCOR RS13150
gene id: 1144275:COCOR_RS13150
uniprot id: H8MTU4
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1144275:COCOR RS32435
gene id: 1144275:COCOR_RS32435
uniprot id: H8MT44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

1144275:COCOR RS14335
gene id: 1144275:COCOR_RS14335
uniprot id: H8MYL5
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS05760
gene id: 1144275:COCOR_RS05760
uniprot id: H8MPB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1144275:COCOR RS13980
gene id: 1144275:COCOR_RS13980
uniprot id: H8MX10
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144275:COCOR RS32225
gene id: 1144275:COCOR_RS32225
uniprot id: H8MT02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1144275:COCOR RS16245
gene id: 1144275:COCOR_RS16245
uniprot id: H8MGJ1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1144275:COCOR RS06725
gene id: 1144275:COCOR_RS06725
uniprot id: H8MTL8
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1144275:COCOR RS09050
gene id: 1144275:COCOR_RS09050
uniprot id: H8N1K6
names: Similarity
messages: Belongs to the GST superfamily.

1144275:COCOR RS26475
gene id: 1144275:COCOR_RS26475
uniprot id: H8MVV8
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

1144275:COCOR RS04450
gene id: 1144275:COCOR_RS04450
uniprot id: H8MK55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

1144275:COCOR RS19285
gene id: 1144275:COCOR_RS19285
uniprot id: H8MSH1
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

1144275:COCOR RS28285
gene id: 1144275:COCOR_RS28285
uniprot id: H8N272
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS14515
gene id: 1144275:COCOR_RS14515
uniprot id: H8MYQ1
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1144275:COCOR RS34940
gene id: 1144275:COCOR_RS34940
uniprot id: H8MFR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the kinesin light chain family.
messages: cytoskeleton

1144275:COCOR RS32180
gene id: 1144275:COCOR_RS32180
uniprot id: H8MSZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1144275:COCOR RS12170
gene id: 1144275:COCOR_RS12170
uniprot id: H8MPJ5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1144275:COCOR RS14990
gene id: 1144275:COCOR_RS14990
uniprot id: H8N0C6
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1144275:COCOR RS25310
gene id: 1144275:COCOR_RS25310
uniprot id: H8MR89
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1144275:COCOR RS39035
gene id: 1144275:COCOR_RS39035
uniprot id: H8MUU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane
messages: CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin).

1144275:COCOR RS15980
gene id: 1144275:COCOR_RS15980
uniprot id: H8MGD8
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1144275:COCOR RS20965
gene id: 1144275:COCOR_RS20965
uniprot id: H8MYW5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.

1144275:COCOR RS07820
gene id: 1144275:COCOR_RS07820
uniprot id: H8MWY8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1144275:COCOR RS01320
gene id: 1144275:COCOR_RS01320
uniprot id: H8MWQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1144275:COCOR RS11330
gene id: 1144275:COCOR_RS11330
uniprot id: H8MLS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1144275:COCOR RS30905
gene id: 1144275:COCOR_RS30905
uniprot id: H8MNQ3
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

1144275:COCOR RS19965
gene id: 1144275:COCOR_RS19965
uniprot id: H8MU79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1144275:COCOR RS05540
gene id: 1144275:COCOR_RS05540
uniprot id: H8MP73
names: Similarity
messages: Belongs to the leucine-binding protein family.

1144275:COCOR RS37460
gene id: 1144275:COCOR_RS37460
uniprot id: H8MP21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1144275:COCOR RS07275
gene id: 1144275:COCOR_RS07275
uniprot id: H8MVA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1144275:COCOR RS30360
gene id: 1144275:COCOR_RS30360
uniprot id: H8ML43
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS29450
gene id: 1144275:COCOR_RS29450
uniprot id: H8MIA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1144275:COCOR RS31650
gene id: 1144275:COCOR_RS31650
uniprot id: H8MQA1
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS24305
gene id: 1144275:COCOR_RS24305
uniprot id: H8MM86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1144275:COCOR RS27895
gene id: 1144275:COCOR_RS27895
uniprot id: H8N0T5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1144275:COCOR RS12015
gene id: 1144275:COCOR_RS12015
uniprot id: H8MPG4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1144275:COCOR RS02680
gene id: 1144275:COCOR_RS02680
uniprot id: H8MEK6
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

1144275:COCOR RS34075
gene id: 1144275:COCOR_RS34075
uniprot id: H8N0W8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1144275:COCOR RS01925
gene id: 1144275:COCOR_RS01925
uniprot id: H8MZT2
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1144275:COCOR RS16575
gene id: 1144275:COCOR_RS16575
uniprot id: H8MHV6
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

1144275:COCOR RS21240
gene id: 1144275:COCOR_RS21240
uniprot id: H8N0F4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1144275:COCOR RS41420
gene id: 1144275:COCOR_RS41420
uniprot id: H8MZJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1144275:COCOR RS13295
gene id: 1144275:COCOR_RS13295
uniprot id: H8MTX3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1144275:COCOR RS33650
gene id: 1144275:COCOR_RS33650
uniprot id: H8MZA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

1144275:COCOR RS00500
gene id: 1144275:COCOR_RS00500
uniprot id: H8MTJ5
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1144275:COCOR RS12365
gene id: 1144275:COCOR_RS12365
uniprot id: H8MQT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1144275:COCOR RS16905
gene id: 1144275:COCOR_RS16905
uniprot id: H8MJ71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1144275:COCOR RS30665
gene id: 1144275:COCOR_RS30665
uniprot id: H8MMF3
names: Similarity
messages: Belongs to the type III secretion exporter family.

1144275:COCOR RS21290
gene id: 1144275:COCOR_RS21290
uniprot id: H8N0G4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1144275:COCOR RS20415
gene id: 1144275:COCOR_RS20415
uniprot id: H8MVU9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1144275:COCOR RS26180
gene id: 1144275:COCOR_RS26180
uniprot id: H8MUB8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1144275:COCOR RS36260
gene id: 1144275:COCOR_RS36260
uniprot id: H8MJX8
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1144275:COCOR RS36585
gene id: 1144275:COCOR_RS36585
uniprot id: H8ML94
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1144275:COCOR RS13050
gene id: 1144275:COCOR_RS13050
uniprot id: H8MSE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1144275:COCOR RS13675
gene id: 1144275:COCOR_RS13675
uniprot id: H8MVH6
names: Cofactor
messages: Binds 1 zinc ion per subunit.

1144275:COCOR RS22620
gene id: 1144275:COCOR_RS22620
uniprot id: H8MGQ1
names: Similarity
messages: Belongs to the pyruvate kinase family.

1144275:COCOR RS22685
gene id: 1144275:COCOR_RS22685
uniprot id: H8MGR4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS25540
gene id: 1144275:COCOR_RS25540
uniprot id: H8MRD6
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS22560
gene id: 1144275:COCOR_RS22560
uniprot id: H8MGN9
names: Similarity
messages: Belongs to the isochorismate synthase family.

1144275:COCOR RS11270
gene id: 1144275:COCOR_RS11270
uniprot id: H8MLR5
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

1144275:COCOR RS11725
gene id: 1144275:COCOR_RS11725
uniprot id: H8MN53
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1144275:COCOR RS18675
gene id: 1144275:COCOR_RS18675
uniprot id: H8MPR8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

1144275:COCOR RS07945
gene id: 1144275:COCOR_RS07945
uniprot id: H8MYE6
names: Similarity
messages: Belongs to the FPG family.

1144275:COCOR RS22830
gene id: 1144275:COCOR_RS22830
uniprot id: H8MHY9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

1144275:COCOR RS05830
gene id: 1144275:COCOR_RS05830
uniprot id: H8MPD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1144275:COCOR RS31630
gene id: 1144275:COCOR_RS31630
uniprot id: H8MQ97
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1144275:COCOR RS36845
gene id: 1144275:COCOR_RS36845
uniprot id: H8MMJ6
names: Similarity
messages: Belongs to the terpene synthase family.

1144275:COCOR RS24795
gene id: 1144275:COCOR_RS24795
uniprot id: H8MNN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1144275:COCOR RS00100
gene id: 1144275:COCOR_RS00100
uniprot id: H8MRY3
names: Similarity
messages: Belongs to the AHA1 family.

1144275:COCOR RS06940
gene id: 1144275:COCOR_RS06940
uniprot id: H8MTR2
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS00035
gene id: 1144275:COCOR_RS00035
uniprot id: H8MRX1
names: Similarity
messages: Belongs to the peptidase M16 family.

1144275:COCOR RS21455
gene id: 1144275:COCOR_RS21455
uniprot id: H8N0J6
names: Similarity
messages: Belongs to the peptidase M16 family.

1144275:COCOR RS31375
gene id: 1144275:COCOR_RS31375
uniprot id: H8MQ46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

1144275:COCOR RS05020
gene id: 1144275:COCOR_RS05020
uniprot id: H8MLM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1144275:COCOR RS21975
gene id: 1144275:COCOR_RS21975
uniprot id: H8N211
names: Similarity
messages: Belongs to the peptidase S45 family.

1144275:COCOR RS08390
gene id: 1144275:COCOR_RS08390
uniprot id: H8N018
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1144275:COCOR RS32945
gene id: 1144275:COCOR_RS32945
uniprot id: H8MW50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1144275:COCOR RS31320
gene id: 1144275:COCOR_RS31320
uniprot id: H8MQ35
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1144275:COCOR RS38510
gene id: 1144275:COCOR_RS38510
uniprot id: H8MT65
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

1144275:COCOR RS35795
gene id: 1144275:COCOR_RS35795
uniprot id: H8MII0
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1144275:COCOR RS26850
gene id: 1144275:COCOR_RS26850
uniprot id: H8MXF8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1144275:COCOR RS17745
gene id: 1144275:COCOR_RS17745
uniprot id: H8MLY5
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1144275:COCOR RS26035
gene id: 1144275:COCOR_RS26035
uniprot id: H8MU92
names: Similarity
messages: Belongs to the pirin family.

1144275:COCOR RS08945
gene id: 1144275:COCOR_RS08945
uniprot id: H8N1I5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1144275:COCOR RS20950
gene id: 1144275:COCOR_RS20950
uniprot id: H8MYW2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1144275:COCOR RS10020
gene id: 1144275:COCOR_RS10020
uniprot id: H8MHL8
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1144275:COCOR RS15215
gene id: 1144275:COCOR_RS15215
uniprot id: H8N1M7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1144275:COCOR RS32310
gene id: 1144275:COCOR_RS32310
uniprot id: H8MT19
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1144275:COCOR RS28410
gene id: 1144275:COCOR_RS28410
uniprot id: H8N297
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1144275:COCOR RS01115
gene id: 1144275:COCOR_RS01115
uniprot id: H8MWK9
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

1144275:COCOR RS34650
gene id: 1144275:COCOR_RS34650
uniprot id: H8N2E1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1144275:COCOR RS05195
gene id: 1144275:COCOR_RS05195
uniprot id: H8MMV4
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS16600
gene id: 1144275:COCOR_RS16600
uniprot id: H8MHW0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1144275:COCOR RS11915
gene id: 1144275:COCOR_RS11915
uniprot id: H8MPE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

1144275:COCOR RS36445
gene id: 1144275:COCOR_RS36445
uniprot id: H8ML66
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS04730
gene id: 1144275:COCOR_RS04730
uniprot id: H8MLG2
names: Similarity
messages: Belongs to the glutamate synthase family.

1144275:COCOR RS35570
gene id: 1144275:COCOR_RS35570
uniprot id: H8MH91
names: Subcellular Location Annotation
messages: Cytoplasm

1144275:COCOR RS30680
gene id: 1144275:COCOR_RS30680
uniprot id: H8MMF6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1144275:COCOR RS14525
gene id: 1144275:COCOR_RS14525
uniprot id: H8MYQ3
names: Similarity
messages: Belongs to the UDPGP type 1 family.

1144275:COCOR RS05055
gene id: 1144275:COCOR_RS05055
uniprot id: H8MMS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1144275:COCOR RS23300
gene id: 1144275:COCOR_RS23300
uniprot id: H8MJD9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1144275:COCOR RS22535
gene id: 1144275:COCOR_RS22535
uniprot id: H8MGN4
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.
messages: Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA).

1144275:COCOR RS10995
gene id: 1144275:COCOR_RS10995
uniprot id: H8MKF8
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

1144275:COCOR RS24805
gene id: 1144275:COCOR_RS24805
uniprot id: H8MNP1
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1144275:COCOR RS04540
gene id: 1144275:COCOR_RS04540
uniprot id: H8MK74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1144275:COCOR RS24030
gene id: 1144275:COCOR_RS24030
uniprot id: H8MKY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1144275:COCOR RS03430
gene id: 1144275:COCOR_RS03430
uniprot id: H8MG54
names: Similarity
messages: Belongs to the peptidase M4 family.

1144275:COCOR RS13505
gene id: 1144275:COCOR_RS13505
uniprot id: H8MVE2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1144275:COCOR RS15635
gene id: 1144275:COCOR_RS15635
uniprot id: H8MF28
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS25120
gene id: 1144275:COCOR_RS25120
uniprot id: H8MPZ9
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1144275:COCOR RS28380
gene id: 1144275:COCOR_RS28380
uniprot id: H8N291
names: Similarity
messages: Belongs to the peptidase M4 family.

1144275:COCOR RS20525
gene id: 1144275:COCOR_RS20525
uniprot id: H8MX95
names: Similarity
messages: Belongs to the universal stress protein A family.

1144275:COCOR RS32825
gene id: 1144275:COCOR_RS32825
uniprot id: H8MFD2
names: Subcellular Location Annotation
messages: Cytoplasm

1144275:COCOR RS34550
gene id: 1144275:COCOR_RS34550
uniprot id: H8N2C1
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1144275:COCOR RS22975
gene id: 1144275:COCOR_RS22975
uniprot id: H8MI20
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144275:COCOR RS40350
gene id: 1144275:COCOR_RS40350
uniprot id: H8MZP6
names: Similarity
messages: Belongs to the GST superfamily.

1144275:COCOR RS01745
gene id: 1144275:COCOR_RS01745
uniprot id: H8MYB5
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1144275:COCOR RS14105
gene id: 1144275:COCOR_RS14105
uniprot id: H8MX35
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144275:COCOR RS28705
gene id: 1144275:COCOR_RS28705
uniprot id: H8MFM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

1144275:COCOR RS26985
gene id: 1144275:COCOR_RS26985
uniprot id: H8MXI5
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1144275:COCOR RS18780
gene id: 1144275:COCOR_RS18780
uniprot id: H8MPU0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144275:COCOR RS33780
gene id: 1144275:COCOR_RS33780
uniprot id: H8MZC7
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1144275:COCOR RS22335
gene id: 1144275:COCOR_RS22335
uniprot id: H8MFF0
names: Similarity
messages: Belongs to the type IB topoisomerase family.

1144275:COCOR RS33180
gene id: 1144275:COCOR_RS33180
uniprot id: H8MW97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1144275:COCOR RS16265
gene id: 1144275:COCOR_RS16265
uniprot id: H8MGJ5
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS05840
gene id: 1144275:COCOR_RS05840
uniprot id: H8MPD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

1144275:COCOR RS23835
gene id: 1144275:COCOR_RS23835
uniprot id: H8MKU3
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1144275:COCOR RS14905
gene id: 1144275:COCOR_RS14905
uniprot id: H8N0A8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1144275:COCOR RS35075
gene id: 1144275:COCOR_RS35075
uniprot id: H8MFU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1144275:COCOR RS34615
gene id: 1144275:COCOR_RS34615
uniprot id: H8N2D4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS02100
gene id: 1144275:COCOR_RS02100
uniprot id: H8MZW6
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS24655
gene id: 1144275:COCOR_RS24655
uniprot id: H8MNL1
names: Similarity
messages: Belongs to the UPF0235 family.

1144275:COCOR RS02560
gene id: 1144275:COCOR_RS02560
uniprot id: H8N1B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1144275:COCOR RS34985
gene id: 1144275:COCOR_RS34985
uniprot id: H8MFS7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

1144275:COCOR RS35225
gene id: 1144275:COCOR_RS35225
uniprot id: H8MFX5
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1144275:COCOR RS10840
gene id: 1144275:COCOR_RS10840
uniprot id: H8MKC6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1144275:COCOR RS13610
gene id: 1144275:COCOR_RS13610
uniprot id: H8MVG3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1144275:COCOR RS08345
gene id: 1144275:COCOR_RS08345
uniprot id: H8N009
names: Similarity
messages: Belongs to the AHA1 family.

1144275:COCOR RS02070
gene id: 1144275:COCOR_RS02070
uniprot id: H8MZW0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1144275:COCOR RS24930
gene id: 1144275:COCOR_RS24930
uniprot id: H8MPW3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1144275:COCOR RS12030
gene id: 1144275:COCOR_RS12030
uniprot id: H8MPG7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1144275:COCOR RS14285
gene id: 1144275:COCOR_RS14285
uniprot id: H8MX73
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

1144275:COCOR RS14730
gene id: 1144275:COCOR_RS14730
uniprot id: H8N074
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1144275:COCOR RS03340
gene id: 1144275:COCOR_RS03340
uniprot id: H8MG38
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1144275:COCOR RS30270
gene id: 1144275:COCOR_RS30270
uniprot id: H8ML24
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1144275:COCOR RS19480
gene id: 1144275:COCOR_RS19480
uniprot id: H8MSL0
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1144275:COCOR RS12060
gene id: 1144275:COCOR_RS12060
uniprot id: H8MPH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1144275:COCOR RS30590
gene id: 1144275:COCOR_RS30590
uniprot id: H8MMD8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1144275:COCOR RS13495
gene id: 1144275:COCOR_RS13495
uniprot id: H8MU09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

1144275:COCOR RS03940
gene id: 1144275:COCOR_RS03940
uniprot id: H8MIQ0
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS27370
gene id: 1144275:COCOR_RS27370
uniprot id: H8MZ45
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1144275:COCOR RS31185
gene id: 1144275:COCOR_RS31185
uniprot id: H8MNW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

1144275:COCOR RS06625
gene id: 1144275:COCOR_RS06625
uniprot id: H8MS73
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1144275:COCOR RS32765
gene id: 1144275:COCOR_RS32765
uniprot id: H8MUN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1144275:COCOR RS31225
gene id: 1144275:COCOR_RS31225
uniprot id: H8MNW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1144275:COCOR RS19485
gene id: 1144275:COCOR_RS19485
uniprot id: H8MSL1
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1144275:COCOR RS15900
gene id: 1144275:COCOR_RS15900
uniprot id: H8MF81
names: Similarity
messages: Belongs to the GST superfamily.

1144275:COCOR RS15220
gene id: 1144275:COCOR_RS15220
uniprot id: H8N1M8
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1144275:COCOR RS27935
gene id: 1144275:COCOR_RS27935
uniprot id: H8N0U3
names: Similarity
messages: Belongs to the type II topoisomerase GyrB family.

1144275:COCOR RS30700
gene id: 1144275:COCOR_RS30700
uniprot id: H8MMG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YscJ lipoprotein family.
messages: Cell outer membrane
messages: Membrane

1144275:COCOR RS09640
gene id: 1144275:COCOR_RS09640
uniprot id: H8MG92
names: Similarity
messages: Belongs to the peptidase S66 family.

1144275:COCOR RS30475
gene id: 1144275:COCOR_RS30475
uniprot id: H8MMB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

1144275:COCOR RS26365
gene id: 1144275:COCOR_RS26365
uniprot id: H8MUF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

1144275:COCOR RS24815
gene id: 1144275:COCOR_RS24815
uniprot id: H8MNP3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS19960
gene id: 1144275:COCOR_RS19960
uniprot id: H8MU78
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

1144275:COCOR RS36235
gene id: 1144275:COCOR_RS36235
uniprot id: H8MJX3
names: Similarity
messages: Belongs to the leucine-binding protein family.

1144275:COCOR RS07405
gene id: 1144275:COCOR_RS07405
uniprot id: H8MVD1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1144275:COCOR RS22175
gene id: 1144275:COCOR_RS22175
uniprot id: H8MFB9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1144275:COCOR RS15675
gene id: 1144275:COCOR_RS15675
uniprot id: H8MF36
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1144275:COCOR RS06315
gene id: 1144275:COCOR_RS06315
uniprot id: H8MS10
names: Similarity
messages: Belongs to the histone deacetylase family.

1144275:COCOR RS29940
gene id: 1144275:COCOR_RS29940
uniprot id: H8MJR1
names: Similarity
messages: Belongs to the peptidase M16 family.

1144275:COCOR RS39985
gene id: 1144275:COCOR_RS39985
uniprot id: H8MY41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1144275:COCOR RS12005
gene id: 1144275:COCOR_RS12005
uniprot id: H8MPG2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1144275:COCOR RS31945
gene id: 1144275:COCOR_RS31945
uniprot id: H8MRL2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1144275:COCOR RS13260
gene id: 1144275:COCOR_RS13260
uniprot id: H8MTW6
names: Similarity
messages: Belongs to the PhoH family.

1144275:COCOR RS35065
gene id: 1144275:COCOR_RS35065
uniprot id: H8MFU3
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1144275:COCOR RS08060
gene id: 1144275:COCOR_RS08060
uniprot id: H8MYH1
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1144275:COCOR RS26615
gene id: 1144275:COCOR_RS26615
uniprot id: H8MVY6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS38110
gene id: 1144275:COCOR_RS38110
uniprot id: H8MRP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

1144275:COCOR RS15275
gene id: 1144275:COCOR_RS15275
uniprot id: H8N1N9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1144275:COCOR RS04525
gene id: 1144275:COCOR_RS04525
uniprot id: H8MK71
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1144275:COCOR RS31970
gene id: 1144275:COCOR_RS31970
uniprot id: H8MRL7
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

1144275:COCOR RS18770
gene id: 1144275:COCOR_RS18770
uniprot id: H8MPT8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144275:COCOR RS01620
gene id: 1144275:COCOR_RS01620
uniprot id: H8MY90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins.
messages: Periplasm

1144275:COCOR RS15270
gene id: 1144275:COCOR_RS15270
uniprot id: H8N1N8
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1144275:COCOR RS24300
gene id: 1144275:COCOR_RS24300
uniprot id: H8MM85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1144275:COCOR RS04235
gene id: 1144275:COCOR_RS04235
uniprot id: H8MK12
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

1144275:COCOR RS37085
gene id: 1144275:COCOR_RS37085
uniprot id: H8MMP4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1144275:COCOR RS38115
gene id: 1144275:COCOR_RS38115
uniprot id: H8MRQ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1144275:COCOR RS05235
gene id: 1144275:COCOR_RS05235
uniprot id: H8MMW2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1144275:COCOR RS27775
gene id: 1144275:COCOR_RS27775
uniprot id: H8N0R0
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

1144275:COCOR RS35530
gene id: 1144275:COCOR_RS35530
uniprot id: H8MH83
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1144275:COCOR RS25110
gene id: 1144275:COCOR_RS25110
uniprot id: H8MPZ7
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS20660
gene id: 1144275:COCOR_RS20660
uniprot id: H8MXC3
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

1144275:COCOR RS11095
gene id: 1144275:COCOR_RS11095
uniprot id: H8MLN0
names: Similarity
messages: Belongs to the frataxin family.

1144275:COCOR RS26195
gene id: 1144275:COCOR_RS26195
uniprot id: H8MUC1
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1144275:COCOR RS21870
gene id: 1144275:COCOR_RS21870
uniprot id: H8N1Z0
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

1144275:COCOR RS37575
gene id: 1144275:COCOR_RS37575
uniprot id: H8MP44
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1144275:COCOR RS10140
gene id: 1144275:COCOR_RS10140
uniprot id: H8MHN6
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1144275:COCOR RS05370
gene id: 1144275:COCOR_RS05370
uniprot id: H8MMY9
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1144275:COCOR RS10025
gene id: 1144275:COCOR_RS10025
uniprot id: H8MHL9
names: Similarity
messages: Belongs to the GSP E family.

1144275:COCOR RS00520
gene id: 1144275:COCOR_RS00520
uniprot id: H8MTJ9
names: Similarity
messages: Belongs to the CapA family.

1144275:COCOR RS29175
gene id: 1144275:COCOR_RS29175
uniprot id: H8MH09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

1144275:COCOR RS28240
gene id: 1144275:COCOR_RS28240
uniprot id: H8N263
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1144275:COCOR RS40430
gene id: 1144275:COCOR_RS40430
uniprot id: H8N142
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1144275:COCOR RS13330
gene id: 1144275:COCOR_RS13330
uniprot id: H8MTY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1144275:COCOR RS13220
gene id: 1144275:COCOR_RS13220
uniprot id: H8MTV8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1144275:COCOR RS19685
gene id: 1144275:COCOR_RS19685
uniprot id: H8MU23
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1144275:COCOR RS07660
gene id: 1144275:COCOR_RS07660
uniprot id: H8MWV5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1144275:COCOR RS22550
gene id: 1144275:COCOR_RS22550
uniprot id: H8MGN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MenH family.
messages: Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
messages: Monomer.

1144275:COCOR RS38070
gene id: 1144275:COCOR_RS38070
uniprot id: H8MRP1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1144275:COCOR RS24800
gene id: 1144275:COCOR_RS24800
uniprot id: H8MNP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1144275:COCOR RS05050
gene id: 1144275:COCOR_RS05050
uniprot id: H8MMS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1144275:COCOR RS15160
gene id: 1144275:COCOR_RS15160
uniprot id: H8N1L6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1144275:COCOR RS06815
gene id: 1144275:COCOR_RS06815
uniprot id: H8MTN6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1144275:COCOR RS25875
gene id: 1144275:COCOR_RS25875
uniprot id: H8MST5
names: Similarity
messages: Belongs to the D-alanine--D-alanine ligase family.

1144275:COCOR RS18930
gene id: 1144275:COCOR_RS18930
uniprot id: H8MR15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1144275:COCOR RS37775
gene id: 1144275:COCOR_RS37775
uniprot id: H8MQD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1144275:COCOR RS05205
gene id: 1144275:COCOR_RS05205
uniprot id: H8MMV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1144275:COCOR RS30500
gene id: 1144275:COCOR_RS30500
uniprot id: H8MMC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1144275:COCOR RS11190
gene id: 1144275:COCOR_RS11190
uniprot id: H8MLP9
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1144275:COCOR RS19130
gene id: 1144275:COCOR_RS19130
uniprot id: H8MR56
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1144275:COCOR RS08835
gene id: 1144275:COCOR_RS08835
uniprot id: H8N1G3
names: Subunit
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

1144275:COCOR RS36225
gene id: 1144275:COCOR_RS36225
uniprot id: H8MJX1
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS12025
gene id: 1144275:COCOR_RS12025
uniprot id: H8MPG6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1144275:COCOR RS21035
gene id: 1144275:COCOR_RS21035
uniprot id: H8MYX9
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1144275:COCOR RS12735
gene id: 1144275:COCOR_RS12735
uniprot id: H8MS89
names: Similarity
messages: Belongs to the aspartokinase family.

1144275:COCOR RS14890
gene id: 1144275:COCOR_RS14890
uniprot id: H8N0A5
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS40045
gene id: 1144275:COCOR_RS40045
uniprot id: H8MZI5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1144275:COCOR RS01570
gene id: 1144275:COCOR_RS01570
uniprot id: H8MY80
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1144275:COCOR RS07720
gene id: 1144275:COCOR_RS07720
uniprot id: H8MWW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1144275:COCOR RS22475
gene id: 1144275:COCOR_RS22475
uniprot id: H8MGM2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1144275:COCOR RS21640
gene id: 1144275:COCOR_RS21640
uniprot id: H8N1U3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1144275:COCOR RS09660
gene id: 1144275:COCOR_RS09660
uniprot id: H8MG96
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1144275:COCOR RS39050
gene id: 1144275:COCOR_RS39050
uniprot id: H8MUU4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1144275:COCOR RS04550
gene id: 1144275:COCOR_RS04550
uniprot id: H8MK76
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS16580
gene id: 1144275:COCOR_RS16580
uniprot id: H8MHV7
names: Similarity
messages: Belongs to the FBPase class 2 family.

1144275:COCOR RS36705
gene id: 1144275:COCOR_RS36705
uniprot id: H8MLB8
names: Subunit
messages: Homodimer.

1144275:COCOR RS36140
gene id: 1144275:COCOR_RS36140
uniprot id: H8MJV4
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1144275:COCOR RS14000
gene id: 1144275:COCOR_RS14000
uniprot id: H8MX14
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1144275:COCOR RS18165
gene id: 1144275:COCOR_RS18165
uniprot id: H8MNB8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1144275:COCOR RS13100
gene id: 1144275:COCOR_RS13100
uniprot id: H8MSF7
names: Similarity
messages: Belongs to the fabD family.

1144275:COCOR RS28140
gene id: 1144275:COCOR_RS28140
uniprot id: H8N243
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YscJ lipoprotein family.
messages: Cell outer membrane
messages: Membrane

1144275:COCOR RS03775
gene id: 1144275:COCOR_RS03775
uniprot id: H8MHH3
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1144275:COCOR RS22160
gene id: 1144275:COCOR_RS22160
uniprot id: H8MFB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1144275:COCOR RS26935
gene id: 1144275:COCOR_RS26935
uniprot id: H8MXH5
names: Similarity
messages: Belongs to the thioredoxin family.

1144275:COCOR RS25790
gene id: 1144275:COCOR_RS25790
uniprot id: H8MSR8
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1144275:COCOR RS06685
gene id: 1144275:COCOR_RS06685
uniprot id: H8MTL0
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1144275:COCOR RS22225
gene id: 1144275:COCOR_RS22225
uniprot id: H8MFC8
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1144275:COCOR RS14090
gene id: 1144275:COCOR_RS14090
uniprot id: H8MX32
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS12605
gene id: 1144275:COCOR_RS12605
uniprot id: H8MQX8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1144275:COCOR RS01690
gene id: 1144275:COCOR_RS01690
uniprot id: H8MYA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FruAB PTS system is involved in fructose transport.

1144275:COCOR RS32770
gene id: 1144275:COCOR_RS32770
uniprot id: H8MUN5
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1144275:COCOR RS39920
gene id: 1144275:COCOR_RS39920
uniprot id: H8MY28
names: Cofactor
messages: Binds 1 FAD per subunit.

1144275:COCOR RS40400
gene id: 1144275:COCOR_RS40400
uniprot id: H8MZQ7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS12210
gene id: 1144275:COCOR_RS12210
uniprot id: H8MPK3
names: Subcellular Location Annotation
messages: Cell outer membrane

1144275:COCOR RS10070
gene id: 1144275:COCOR_RS10070
uniprot id: H8MHM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1144275:COCOR RS24505
gene id: 1144275:COCOR_RS24505
uniprot id: H8MNH8
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

1144275:COCOR RS04215
gene id: 1144275:COCOR_RS04215
uniprot id: H8MIV5
names: Similarity
messages: Belongs to the peptidase C59 family.

1144275:COCOR RS19310
gene id: 1144275:COCOR_RS19310
uniprot id: H8MSH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1144275:COCOR RS26320
gene id: 1144275:COCOR_RS26320
uniprot id: H8MUE6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS37080
gene id: 1144275:COCOR_RS37080
uniprot id: H8MMP3
names: Similarity
messages: Belongs to the thioredoxin family.

1144275:COCOR RS10950
gene id: 1144275:COCOR_RS10950
uniprot id: H8MKE8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1144275:COCOR RS28280
gene id: 1144275:COCOR_RS28280
uniprot id: H8N271
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1144275:COCOR RS25295
gene id: 1144275:COCOR_RS25295
uniprot id: H8MR86
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS13105
gene id: 1144275:COCOR_RS13105
uniprot id: H8MTT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1144275:COCOR RS28580
gene id: 1144275:COCOR_RS28580
uniprot id: H8MFJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the xanthine dehydrogenase family.
messages: Peroxisome

1144275:COCOR RS25835
gene id: 1144275:COCOR_RS25835
uniprot id: H8MSS7
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1144275:COCOR RS32125
gene id: 1144275:COCOR_RS32125
uniprot id: H8MSY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1144275:COCOR RS04140
gene id: 1144275:COCOR_RS04140
uniprot id: H8MIU0
names: Similarity
messages: Belongs to the glutamine synthetase family.

1144275:COCOR RS35500
gene id: 1144275:COCOR_RS35500
uniprot id: H8MH77
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

1144275:COCOR RS33190
gene id: 1144275:COCOR_RS33190
uniprot id: H8MW99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1144275:COCOR RS04715
gene id: 1144275:COCOR_RS04715
uniprot id: H8MLF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1144275:COCOR RS27690
gene id: 1144275:COCOR_RS27690
uniprot id: H8N0P2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane
messages: Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.

1144275:COCOR RS10320
gene id: 1144275:COCOR_RS10320
uniprot id: H8MIX2
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS04345
gene id: 1144275:COCOR_RS04345
uniprot id: H8MK34
names: Function
names: Similarity
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.

1144275:COCOR RS05135
gene id: 1144275:COCOR_RS05135
uniprot id: H8MMU2
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1144275:COCOR RS15305
gene id: 1144275:COCOR_RS15305
uniprot id: H8N1P4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1144275:COCOR RS24735
gene id: 1144275:COCOR_RS24735
uniprot id: H8MNM7
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1144275:COCOR RS34420
gene id: 1144275:COCOR_RS34420
uniprot id: H8N137
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1144275:COCOR RS00410
gene id: 1144275:COCOR_RS00410
uniprot id: H8MTH6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome
messages: Secreted

1144275:COCOR RS26030
gene id: 1144275:COCOR_RS26030
uniprot id: H8MSW8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144275:COCOR RS19385
gene id: 1144275:COCOR_RS19385
uniprot id: H8MSJ1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1144275:COCOR RS19345
gene id: 1144275:COCOR_RS19345
uniprot id: H8MSI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

1144275:COCOR RS25235
gene id: 1144275:COCOR_RS25235
uniprot id: H8MQ22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1144275:COCOR RS08440
gene id: 1144275:COCOR_RS08440
uniprot id: H8N029
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1144275:COCOR RS15235
gene id: 1144275:COCOR_RS15235
uniprot id: H8N1N1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1144275:COCOR RS32200
gene id: 1144275:COCOR_RS32200
uniprot id: H8MSZ7
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

1144275:COCOR RS21600
gene id: 1144275:COCOR_RS21600
uniprot id: H8N0M7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1144275:COCOR RS05150
gene id: 1144275:COCOR_RS05150
uniprot id: H8MMU5
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1144275:COCOR RS02585
gene id: 1144275:COCOR_RS02585
uniprot id: H8N1B8
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

1144275:COCOR RS24500
gene id: 1144275:COCOR_RS24500
uniprot id: H8MNH7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144275:COCOR RS33660
gene id: 1144275:COCOR_RS33660
uniprot id: H8MZA3
names: Similarity
messages: Belongs to the catalase family.

1144275:COCOR RS23685
gene id: 1144275:COCOR_RS23685
uniprot id: H8MKR3
names: Similarity
messages: Belongs to the UPF0111 family.

1144275:COCOR RS06015
gene id: 1144275:COCOR_RS06015
uniprot id: H8MQL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1144275:COCOR RS12190
gene id: 1144275:COCOR_RS12190
uniprot id: H8MPJ9
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

1144275:COCOR RS28100
gene id: 1144275:COCOR_RS28100
uniprot id: H8N235
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane

1144275:COCOR RS20410
gene id: 1144275:COCOR_RS20410
uniprot id: H8MVU8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1144275:COCOR RS33175
gene id: 1144275:COCOR_RS33175
uniprot id: H8MW96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1144275:COCOR RS09745
gene id: 1144275:COCOR_RS09745
uniprot id: H8MGB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1144275:COCOR RS35930
gene id: 1144275:COCOR_RS35930
uniprot id: H8MIK7
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1144275:COCOR RS17755
gene id: 1144275:COCOR_RS17755
uniprot id: H8MLY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1144275:COCOR RS02125
gene id: 1144275:COCOR_RS02125
uniprot id: H8MZX1
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS17360
gene id: 1144275:COCOR_RS17360
uniprot id: H8MKL0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1144275:COCOR RS08140
gene id: 1144275:COCOR_RS08140
uniprot id: H8MYI7
names: Similarity
messages: Belongs to the EndA/NucM nuclease family.

1144275:COCOR RS33735
gene id: 1144275:COCOR_RS33735
uniprot id: H8MZB8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1144275:COCOR RS27730
gene id: 1144275:COCOR_RS27730
uniprot id: H8N0Q0
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1144275:COCOR RS02900
gene id: 1144275:COCOR_RS02900
uniprot id: H8MEQ0
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS29030
gene id: 1144275:COCOR_RS29030
uniprot id: H8MGY2
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS14175
gene id: 1144275:COCOR_RS14175
uniprot id: H8MX49
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS26805
gene id: 1144275:COCOR_RS26805
uniprot id: H8MW24
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

1144275:COCOR RS21795
gene id: 1144275:COCOR_RS21795
uniprot id: H8N1X4
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS19465
gene id: 1144275:COCOR_RS19465
uniprot id: H8MSK7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS07785
gene id: 1144275:COCOR_RS07785
uniprot id: H8MWY2
names: Function
names: Subcellular Location Annotation
messages: May play a structural or regulatory role in gas vesicle synthesis.
messages: Vesicle
messages: gas vesicle

1144275:COCOR RS35920
gene id: 1144275:COCOR_RS35920
uniprot id: H8MIK5
names: Similarity
messages: Belongs to the AHA1 family.

1144275:COCOR RS33570
gene id: 1144275:COCOR_RS33570
uniprot id: H8MXV3
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1144275:COCOR RS28125
gene id: 1144275:COCOR_RS28125
uniprot id: H8N240
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cytoplasm

1144275:COCOR RS28550
gene id: 1144275:COCOR_RS28550
uniprot id: H8MFJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

1144275:COCOR RS28080
gene id: 1144275:COCOR_RS28080
uniprot id: H8N231
names: Similarity
messages: Belongs to the type III secretion exporter family.

1144275:COCOR RS02895
gene id: 1144275:COCOR_RS02895
uniprot id: H8MEP9
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1144275:COCOR RS35805
gene id: 1144275:COCOR_RS35805
uniprot id: H8MII2
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1144275:COCOR RS04430
gene id: 1144275:COCOR_RS04430
uniprot id: H8MK51
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS19400
gene id: 1144275:COCOR_RS19400
uniprot id: H8MSJ4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

1144275:COCOR RS24480
gene id: 1144275:COCOR_RS24480
uniprot id: H8MNH3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

1144275:COCOR RS30940
gene id: 1144275:COCOR_RS30940
uniprot id: H8MNR0
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS04570
gene id: 1144275:COCOR_RS04570
uniprot id: H8MK80
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1144275:COCOR RS30420
gene id: 1144275:COCOR_RS30420
uniprot id: H8ML55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1144275:COCOR RS21970
gene id: 1144275:COCOR_RS21970
uniprot id: H8N210
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1144275:COCOR RS34800
gene id: 1144275:COCOR_RS34800
uniprot id: H8N2H2
names: Similarity
messages: Belongs to the peptidase S1B family.

1144275:COCOR RS24135
gene id: 1144275:COCOR_RS24135
uniprot id: H8MM52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1144275:COCOR RS30435
gene id: 1144275:COCOR_RS30435
uniprot id: H8ML57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

1144275:COCOR RS32250
gene id: 1144275:COCOR_RS32250
uniprot id: H8MT07
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1144275:COCOR RS19865
gene id: 1144275:COCOR_RS19865
uniprot id: H8MU59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1144275:COCOR RS30460
gene id: 1144275:COCOR_RS30460
uniprot id: H8ML62
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS19425
gene id: 1144275:COCOR_RS19425
uniprot id: H8MSJ9
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1144275:COCOR RS24670
gene id: 1144275:COCOR_RS24670
uniprot id: H8MNL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1144275:COCOR RS18680
gene id: 1144275:COCOR_RS18680
uniprot id: H8MPR9
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1144275:COCOR RS26115
gene id: 1144275:COCOR_RS26115
uniprot id: H8MUA7
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS11735
gene id: 1144275:COCOR_RS11735
uniprot id: H8MN55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

1144275:COCOR RS16925
gene id: 1144275:COCOR_RS16925
uniprot id: H8MJ74
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144275:COCOR RS23260
gene id: 1144275:COCOR_RS23260
uniprot id: H8MJC8
names: Similarity
messages: Belongs to the aspartokinase family.

1144275:COCOR RS05460
gene id: 1144275:COCOR_RS05460
uniprot id: H8MP57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1144275:COCOR RS12630
gene id: 1144275:COCOR_RS12630
uniprot id: H8MQY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1144275:COCOR RS22490
gene id: 1144275:COCOR_RS22490
uniprot id: H8MGM5
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1144275:COCOR RS26495
gene id: 1144275:COCOR_RS26495
uniprot id: H8MVW2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1144275:COCOR RS18665
gene id: 1144275:COCOR_RS18665
uniprot id: H8MPR6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Belongs to the Nudix hydrolase family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1144275:COCOR RS16095
gene id: 1144275:COCOR_RS16095
uniprot id: H8MGG0
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS34775
gene id: 1144275:COCOR_RS34775
uniprot id: H8N2G7
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

1144275:COCOR RS20560
gene id: 1144275:COCOR_RS20560
uniprot id: H8MXA2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144275:COCOR RS32940
gene id: 1144275:COCOR_RS32940
uniprot id: H8MW49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1144275:COCOR RS33755
gene id: 1144275:COCOR_RS33755
uniprot id: H8MZC2
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS22600
gene id: 1144275:COCOR_RS22600
uniprot id: H8MGP7
names: Similarity
messages: Belongs to the citrate synthase family.

1144275:COCOR RS18630
gene id: 1144275:COCOR_RS18630
uniprot id: H8MPQ9
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

1144275:COCOR RS17555
gene id: 1144275:COCOR_RS17555
uniprot id: H8MKP5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144275:COCOR RS31825
gene id: 1144275:COCOR_RS31825
uniprot id: H8MRI8
names: Similarity
messages: Belongs to the peptidase S58 family.

1144275:COCOR RS00530
gene id: 1144275:COCOR_RS00530
uniprot id: H8MTK1
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS06520
gene id: 1144275:COCOR_RS06520
uniprot id: H8MS52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

1144275:COCOR RS16860
gene id: 1144275:COCOR_RS16860
uniprot id: H8MJ62
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1144275:COCOR RS19295
gene id: 1144275:COCOR_RS19295
uniprot id: H8MSH3
names: Similarity
messages: Belongs to the peptidase S58 family.

1144275:COCOR RS05585
gene id: 1144275:COCOR_RS05585
uniprot id: H8MP82
names: Similarity
messages: Belongs to the peptidase C56 family.

1144275:COCOR RS15110
gene id: 1144275:COCOR_RS15110
uniprot id: H8N0F0
names: Similarity
messages: Belongs to the peptidase S8 family.

1144275:COCOR RS35035
gene id: 1144275:COCOR_RS35035
uniprot id: H8MFT7
names: Similarity
messages: Belongs to the Nth/MutY family.

1144275:COCOR RS31685
gene id: 1144275:COCOR_RS31685
uniprot id: H8MRG0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1144275:COCOR RS37340
gene id: 1144275:COCOR_RS37340
uniprot id: H8MNZ7
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1144275:COCOR RS25135
gene id: 1144275:COCOR_RS25135
uniprot id: H8MQ02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1144275:COCOR RS25630
gene id: 1144275:COCOR_RS25630
uniprot id: H8MRF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1144275:COCOR RS15640
gene id: 1144275:COCOR_RS15640
uniprot id: H8MF29
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144275:COCOR RS07620
gene id: 1144275:COCOR_RS07620
uniprot id: H8MWU7
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1144275:COCOR RS01345
gene id: 1144275:COCOR_RS01345
uniprot id: H8MWQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Belongs to the TonB-dependent receptor family.
messages: Cell inner membrane
messages: Cell outer membrane

1144275:COCOR RS18985
gene id: 1144275:COCOR_RS18985
uniprot id: H8MR26
names: Similarity
messages: Belongs to the DEAD box helicase family.

1144275:COCOR RS37030
gene id: 1144275:COCOR_RS37030
uniprot id: H8MMN3
names: Similarity
messages: Belongs to the DNase I family.

1144275:COCOR RS23010
gene id: 1144275:COCOR_RS23010
uniprot id: H8MI26
names: Similarity
messages: Belongs to the CapA family.

1144275:COCOR RS03410
gene id: 1144275:COCOR_RS03410
uniprot id: H8MG50
names: Similarity
messages: Belongs to the peptidase M16 family.

1144275:COCOR RS14810
gene id: 1144275:COCOR_RS14810
uniprot id: H8N090
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1144275:COCOR RS29750
gene id: 1144275:COCOR_RS29750
uniprot id: H8MJM1
names: Similarity
messages: Belongs to the peptidase S8 family.

1144275:COCOR RS06665
gene id: 1144275:COCOR_RS06665
uniprot id: H8MTK6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1144275:COCOR RS08190
gene id: 1144275:COCOR_RS08190
uniprot id: H8MYJ7
names: Similarity
messages: Belongs to the UPF0178 family.

1144275:COCOR RS38140
gene id: 1144275:COCOR_RS38140
uniprot id: H8MRQ5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1144275:COCOR RS26715
gene id: 1144275:COCOR_RS26715
uniprot id: H8MW06
names: Function
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.

1144275:COCOR RS17295
gene id: 1144275:COCOR_RS17295
uniprot id: H8MKJ7
names: Subcellular Location Annotation
messages: Cell inner membrane

1144275:COCOR RS30135
gene id: 1144275:COCOR_RS30135
uniprot id: H8ML01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1144275:COCOR RS39395
gene id: 1144275:COCOR_RS39395
uniprot id: H8MWE6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1144275:COCOR RS09125
gene id: 1144275:COCOR_RS09125
uniprot id: H8MET9
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

1144275:COCOR RS11765
gene id: 1144275:COCOR_RS11765
uniprot id: H8MN62
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

1144275:COCOR RS20475
gene id: 1144275:COCOR_RS20475
uniprot id: H8MX85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1144275:COCOR RS07915
gene id: 1144275:COCOR_RS07915
uniprot id: H8MYE0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1144275:COCOR RS28690
gene id: 1144275:COCOR_RS28690
uniprot id: H8MFL9
names: Similarity
messages: Belongs to the YkuD family.

1144275:COCOR RS35245
gene id: 1144275:COCOR_RS35245
uniprot id: H8MH26
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS31195
gene id: 1144275:COCOR_RS31195
uniprot id: H8MNW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase CarF family.
messages: Membrane

1144275:COCOR RS08365
gene id: 1144275:COCOR_RS08365
uniprot id: H8N013
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1144275:COCOR RS15310
gene id: 1144275:COCOR_RS15310
uniprot id: H8N1P5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1144275:COCOR RS00820
gene id: 1144275:COCOR_RS00820
uniprot id: H8MV29
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1144275:COCOR RS13690
gene id: 1144275:COCOR_RS13690
uniprot id: H8MVH9
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS29410
gene id: 1144275:COCOR_RS29410
uniprot id: H8MI99
names: Similarity
messages: Belongs to the peptidase M24B family.

1144275:COCOR RS07040
gene id: 1144275:COCOR_RS07040
uniprot id: H8MTT2
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1144275:COCOR RS38780
gene id: 1144275:COCOR_RS38780
uniprot id: H8MTB7
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1144275:COCOR RS27905
gene id: 1144275:COCOR_RS27905
uniprot id: H8N0T7
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

1144275:COCOR RS13125
gene id: 1144275:COCOR_RS13125
uniprot id: H8MTT9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS27095
gene id: 1144275:COCOR_RS27095
uniprot id: H8MXK6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1144275:COCOR RS05835
gene id: 1144275:COCOR_RS05835
uniprot id: H8MPD3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1144275:COCOR RS31690
gene id: 1144275:COCOR_RS31690
uniprot id: H8MRG1
names: Similarity
messages: Belongs to the intimin/invasin family.

1144275:COCOR RS25950
gene id: 1144275:COCOR_RS25950
uniprot id: H8MSV1
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS00355
gene id: 1144275:COCOR_RS00355
uniprot id: H8MTG5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

1144275:COCOR RS30485
gene id: 1144275:COCOR_RS30485
uniprot id: H8MMB7
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS13285
gene id: 1144275:COCOR_RS13285
uniprot id: H8MTX1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1144275:COCOR RS21395
gene id: 1144275:COCOR_RS21395
uniprot id: H8N0I4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

1144275:COCOR RS28480
gene id: 1144275:COCOR_RS28480
uniprot id: H8MFH8
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

1144275:COCOR RS31955
gene id: 1144275:COCOR_RS31955
uniprot id: H8MRL4
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1144275:COCOR RS01565
gene id: 1144275:COCOR_RS01565
uniprot id: H8MY79
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144275:COCOR RS27160
gene id: 1144275:COCOR_RS27160
uniprot id: H8MXL9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1144275:COCOR RS11710
gene id: 1144275:COCOR_RS11710
uniprot id: H8MN50
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1144275:COCOR RS10040
gene id: 1144275:COCOR_RS10040
uniprot id: H8MHM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1144275:COCOR RS26885
gene id: 1144275:COCOR_RS26885
uniprot id: H8MXG5
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1144275:COCOR RS24025
gene id: 1144275:COCOR_RS24025
uniprot id: H8MKY1
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS12390
gene id: 1144275:COCOR_RS12390
uniprot id: H8MQT6
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1144275:COCOR RS10130
gene id: 1144275:COCOR_RS10130
uniprot id: H8MHN4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1144275:COCOR RS19975
gene id: 1144275:COCOR_RS19975
uniprot id: H8MU81
names: Similarity
messages: Belongs to the peptidase S1B family.

1144275:COCOR RS03785
gene id: 1144275:COCOR_RS03785
uniprot id: H8MHH5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1144275:COCOR RS01220
gene id: 1144275:COCOR_RS01220
uniprot id: H8MWN0
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS00430
gene id: 1144275:COCOR_RS00430
uniprot id: H8MTI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1144275:COCOR RS10575
gene id: 1144275:COCOR_RS10575
uniprot id: H8MJ22
names: Similarity
messages: Belongs to the cytochrome P450 family.

1144275:COCOR RS32035
gene id: 1144275:COCOR_RS32035
uniprot id: H8MRM9
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

1144275:COCOR RS05730
gene id: 1144275:COCOR_RS05730
uniprot id: H8MPB2
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

1144275:COCOR RS14645
gene id: 1144275:COCOR_RS14645
uniprot id: H8MYS5
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

1144275:COCOR RS26105
gene id: 1144275:COCOR_RS26105
uniprot id: H8MUA5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1144275:COCOR RS13860
gene id: 1144275:COCOR_RS13860
uniprot id: H8MVL3
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS06525
gene id: 1144275:COCOR_RS06525
uniprot id: H8MS53
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144275:COCOR RS24920
gene id: 1144275:COCOR_RS24920
uniprot id: H8MPW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.

1144275:COCOR RS41405
gene id: 1144275:COCOR_RS41405
uniprot id: H8MY33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1144275:COCOR RS03290
gene id: 1144275:COCOR_RS03290
uniprot id: H8MG28
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1144275:COCOR RS37895
gene id: 1144275:COCOR_RS37895
uniprot id: H8MQF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1144275:COCOR RS16195
gene id: 1144275:COCOR_RS16195
uniprot id: H8MGI1
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

1144275:COCOR RS12220
gene id: 1144275:COCOR_RS12220
uniprot id: H8MPK5
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS29300
gene id: 1144275:COCOR_RS29300
uniprot id: H8MI79
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1144275:COCOR RS36955
gene id: 1144275:COCOR_RS36955
uniprot id: H8MML8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

1144275:COCOR RS37195
gene id: 1144275:COCOR_RS37195
uniprot id: H8MMR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1144275:COCOR RS30630
gene id: 1144275:COCOR_RS30630
uniprot id: H8MME6
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS32390
gene id: 1144275:COCOR_RS32390
uniprot id: H8MT35
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase involved in purine salvage.

1144275:COCOR RS33305
gene id: 1144275:COCOR_RS33305
uniprot id: H8MXP9
names: Function
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).

1144275:COCOR RS01610
gene id: 1144275:COCOR_RS01610
uniprot id: H8MY88
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1144275:COCOR RS12440
gene id: 1144275:COCOR_RS12440
uniprot id: H8MQU6
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1144275:COCOR RS28000
gene id: 1144275:COCOR_RS28000
uniprot id: H8N0V6
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1144275:COCOR RS07940
gene id: 1144275:COCOR_RS07940
uniprot id: H8MYE5
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1144275:COCOR RS36475
gene id: 1144275:COCOR_RS36475
uniprot id: H8ML72
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1144275:COCOR RS21405
gene id: 1144275:COCOR_RS21405
uniprot id: H8N0I6
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1144275:COCOR RS01255
gene id: 1144275:COCOR_RS01255
uniprot id: H8MWN7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

1144275:COCOR RS32000
gene id: 1144275:COCOR_RS32000
uniprot id: H8MRM2
names: Similarity
names: Subunit
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.
messages: Heterodimer of a large and a small subunit.

1144275:COCOR RS03360
gene id: 1144275:COCOR_RS03360
uniprot id: H8MG41
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144275:COCOR RS18580
gene id: 1144275:COCOR_RS18580
uniprot id: H8MPP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1144275:COCOR RS37390
gene id: 1144275:COCOR_RS37390
uniprot id: H8MP07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1144275:COCOR RS33770
gene id: 1144275:COCOR_RS33770
uniprot id: H8MZC5
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS04625
gene id: 1144275:COCOR_RS04625
uniprot id: H8MK91
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1144275:COCOR RS25230
gene id: 1144275:COCOR_RS25230
uniprot id: H8MQ21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1144275:COCOR RS10440
gene id: 1144275:COCOR_RS10440
uniprot id: H8MIZ6
names: Similarity
messages: Belongs to the ArsC family.

1144275:COCOR RS13195
gene id: 1144275:COCOR_RS13195
uniprot id: H8MTV3
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1144275:COCOR RS30055
gene id: 1144275:COCOR_RS30055
uniprot id: H8MKY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1144275:COCOR RS22245
gene id: 1144275:COCOR_RS22245
uniprot id: H8MFD2
names: Subcellular Location Annotation
messages: Cytoplasm

1144275:COCOR RS36645
gene id: 1144275:COCOR_RS36645
uniprot id: H8MLA6
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1144275:COCOR RS30440
gene id: 1144275:COCOR_RS30440
uniprot id: H8ML58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein.

1144275:COCOR RS05740
gene id: 1144275:COCOR_RS05740
uniprot id: H8MPB4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1144275:COCOR RS00620
gene id: 1144275:COCOR_RS00620
uniprot id: H8MUZ1
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1144275:COCOR RS33760
gene id: 1144275:COCOR_RS33760
uniprot id: H8MZC3
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS08210
gene id: 1144275:COCOR_RS08210
uniprot id: H8MYK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1144275:COCOR RS00900
gene id: 1144275:COCOR_RS00900
uniprot id: H8MV45
names: Similarity
messages: Belongs to the peptidase S8 family.

1144275:COCOR RS30085
gene id: 1144275:COCOR_RS30085
uniprot id: H8MKZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1144275:COCOR RS13120
gene id: 1144275:COCOR_RS13120
uniprot id: H8MTT8
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1144275:COCOR RS41120
gene id: 1144275:COCOR_RS41120
uniprot id: H8MGY6
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS10680
gene id: 1144275:COCOR_RS10680
uniprot id: H8MK95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1144275:COCOR RS03570
gene id: 1144275:COCOR_RS03570
uniprot id: H8MHD2
names: Similarity
messages: Belongs to the BMP lipoprotein family.

1144275:COCOR RS32255
gene id: 1144275:COCOR_RS32255
uniprot id: H8MT08
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1144275:COCOR RS27675
gene id: 1144275:COCOR_RS27675
uniprot id: H8N0N9
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1144275:COCOR RS21860
gene id: 1144275:COCOR_RS21860
uniprot id: H8N1Y8
names: Cofactor
messages: Binds 1 phosphopantetheine covalently.

1144275:COCOR RS30610
gene id: 1144275:COCOR_RS30610
uniprot id: H8MME2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1144275:COCOR RS18570
gene id: 1144275:COCOR_RS18570
uniprot id: H8MPP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1144275:COCOR RS32515
gene id: 1144275:COCOR_RS32515
uniprot id: H8MUI3
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS40340
gene id: 1144275:COCOR_RS40340
uniprot id: H8MZP4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1144275:COCOR RS34735
gene id: 1144275:COCOR_RS34735
uniprot id: H8N2F9
names: Similarity
messages: Belongs to the SUI1 family.

1144275:COCOR RS04470
gene id: 1144275:COCOR_RS04470
uniprot id: H8MK59
names: Similarity
messages: In the C-terminal section; belongs to the NRP synthetase family.

1144275:COCOR RS33330
gene id: 1144275:COCOR_RS33330
uniprot id: H8MXQ5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1144275:COCOR RS12955
gene id: 1144275:COCOR_RS12955
uniprot id: H8MSC9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

1144275:COCOR RS07850
gene id: 1144275:COCOR_RS07850
uniprot id: H8MWZ4
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS17545
gene id: 1144275:COCOR_RS17545
uniprot id: H8MKP3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS32895
gene id: 1144275:COCOR_RS32895
uniprot id: H8MW40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1144275:COCOR RS24200
gene id: 1144275:COCOR_RS24200
uniprot id: H8MM65
names: Similarity
messages: Belongs to the TlyA family.

1144275:COCOR RS23420
gene id: 1144275:COCOR_RS23420
uniprot id: H8MJG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

1144275:COCOR RS33040
gene id: 1144275:COCOR_RS33040
uniprot id: H8MW69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1144275:COCOR RS08230
gene id: 1144275:COCOR_RS08230
uniprot id: H8MYK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1144275:COCOR RS05000
gene id: 1144275:COCOR_RS05000
uniprot id: H8MLL6
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1144275:COCOR RS21065
gene id: 1144275:COCOR_RS21065
uniprot id: H8MYY5
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

1144275:COCOR RS38500
gene id: 1144275:COCOR_RS38500
uniprot id: H8MT63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1144275:COCOR RS23405
gene id: 1144275:COCOR_RS23405
uniprot id: H8MJF9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1144275:COCOR RS38015
gene id: 1144275:COCOR_RS38015
uniprot id: H8MQH8
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS32235
gene id: 1144275:COCOR_RS32235
uniprot id: H8MT04
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1144275:COCOR RS04055
gene id: 1144275:COCOR_RS04055
uniprot id: H8MIS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1144275:COCOR RS39605
gene id: 1144275:COCOR_RS39605
uniprot id: H8MWI1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1144275:COCOR RS31425
gene id: 1144275:COCOR_RS31425
uniprot id: H8MQ56
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

1144275:COCOR RS20605
gene id: 1144275:COCOR_RS20605
uniprot id: H8MXB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1144275:COCOR RS24740
gene id: 1144275:COCOR_RS24740
uniprot id: H8MNM8
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1144275:COCOR RS28650
gene id: 1144275:COCOR_RS28650
uniprot id: H8MFL1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

1144275:COCOR RS14970
gene id: 1144275:COCOR_RS14970
uniprot id: H8N0C2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1144275:COCOR RS07875
gene id: 1144275:COCOR_RS07875
uniprot id: H8MYD2
names: Subcellular Location Annotation
messages: Cytoplasm

1144275:COCOR RS10810
gene id: 1144275:COCOR_RS10810
uniprot id: H8MKC0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1144275:COCOR RS30465
gene id: 1144275:COCOR_RS30465
uniprot id: H8MMB3
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS03680
gene id: 1144275:COCOR_RS03680
uniprot id: H8MHF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Belongs to the TonB-dependent receptor family.
messages: Cell inner membrane
messages: Cell outer membrane

1144275:COCOR RS10550
gene id: 1144275:COCOR_RS10550
uniprot id: H8MJ17
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1144275:COCOR RS39690
gene id: 1144275:COCOR_RS39690
uniprot id: H8MXY0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS03720
gene id: 1144275:COCOR_RS03720
uniprot id: H8MHG2
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1144275:COCOR RS18690
gene id: 1144275:COCOR_RS18690
uniprot id: H8MPS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

1144275:COCOR RS28755
gene id: 1144275:COCOR_RS28755
uniprot id: H8MFN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1144275:COCOR RS34740
gene id: 1144275:COCOR_RS34740
uniprot id: H8N2G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

1144275:COCOR RS02470
gene id: 1144275:COCOR_RS02470
uniprot id: H8N197
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1144275:COCOR RS08805
gene id: 1144275:COCOR_RS08805
uniprot id: H8N1F7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1144275:COCOR RS26490
gene id: 1144275:COCOR_RS26490
uniprot id: H8MVW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1144275:COCOR RS30890
gene id: 1144275:COCOR_RS30890
uniprot id: H8MNQ0
names: Similarity
messages: Belongs to the PspA/IM30 family.

1144275:COCOR RS28855
gene id: 1144275:COCOR_RS28855
uniprot id: H8MGU9
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS04935
gene id: 1144275:COCOR_RS04935
uniprot id: H8MLK3
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS19730
gene id: 1144275:COCOR_RS19730
uniprot id: H8MU32
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1144275:COCOR RS29535
gene id: 1144275:COCOR_RS29535
uniprot id: H8MIC4
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS11090
gene id: 1144275:COCOR_RS11090
uniprot id: H8MLM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1144275:COCOR RS40095
gene id: 1144275:COCOR_RS40095
uniprot id: H8MZJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1144275:COCOR RS31470
gene id: 1144275:COCOR_RS31470
uniprot id: H8MQ65
names: Cofactor
messages: Binds 1 Ca(2+) ion per subunit.

1144275:COCOR RS24545
gene id: 1144275:COCOR_RS24545
uniprot id: H8MNI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

1144275:COCOR RS23850
gene id: 1144275:COCOR_RS23850
uniprot id: H8MKU6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1144275:COCOR RS33625
gene id: 1144275:COCOR_RS33625
uniprot id: H8MXW4
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1144275:COCOR RS27805
gene id: 1144275:COCOR_RS27805
uniprot id: H8N0R6
names: Similarity
messages: Belongs to the peptidase U62 family.

1144275:COCOR RS14745
gene id: 1144275:COCOR_RS14745
uniprot id: H8N077
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1144275:COCOR RS21840
gene id: 1144275:COCOR_RS21840
uniprot id: H8N1Y4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1144275:COCOR RS19545
gene id: 1144275:COCOR_RS19545
uniprot id: H8MSM3
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1144275:COCOR RS21645
gene id: 1144275:COCOR_RS21645
uniprot id: H8N1U4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

1144275:COCOR RS08395
gene id: 1144275:COCOR_RS08395
uniprot id: H8N019
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1144275:COCOR RS25725
gene id: 1144275:COCOR_RS25725
uniprot id: H8MSQ5
names: Similarity
messages: Belongs to the XFP family.

1144275:COCOR RS09060
gene id: 1144275:COCOR_RS09060
uniprot id: H8MES7
names: Similarity
messages: Belongs to the AHA1 family.

1144275:COCOR RS27550
gene id: 1144275:COCOR_RS27550
uniprot id: H8MZ82
names: Similarity
messages: Belongs to the peptidase C69 family.

1144275:COCOR RS02645
gene id: 1144275:COCOR_RS02645
uniprot id: H8MEJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1144275:COCOR RS16240
gene id: 1144275:COCOR_RS16240
uniprot id: H8MGJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1144275:COCOR RS13640
gene id: 1144275:COCOR_RS13640
uniprot id: H8MVG9
names: Similarity
messages: Belongs to the cytochrome P450 family.

1144275:COCOR RS24780
gene id: 1144275:COCOR_RS24780
uniprot id: H8MNN6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1144275:COCOR RS20005
gene id: 1144275:COCOR_RS20005
uniprot id: H8MU87
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

1144275:COCOR RS21210
gene id: 1144275:COCOR_RS21210
uniprot id: H8MZ16
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1144275:COCOR RS27285
gene id: 1144275:COCOR_RS27285
uniprot id: H8MZ26
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1144275:COCOR RS29695
gene id: 1144275:COCOR_RS29695
uniprot id: H8MJL0
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1144275:COCOR RS17330
gene id: 1144275:COCOR_RS17330
uniprot id: H8MKK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

1144275:COCOR RS30070
gene id: 1144275:COCOR_RS30070
uniprot id: H8MKY8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1144275:COCOR RS22415
gene id: 1144275:COCOR_RS22415
uniprot id: H8MFG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1144275:COCOR RS31530
gene id: 1144275:COCOR_RS31530
uniprot id: H8MQ79
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1144275:COCOR RS10720
gene id: 1144275:COCOR_RS10720
uniprot id: H8MKA3
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS15415
gene id: 1144275:COCOR_RS15415
uniprot id: H8N1R5
names: Subcellular Location Annotation
messages: Nucleus

1144275:COCOR RS10615
gene id: 1144275:COCOR_RS10615
uniprot id: H8MJ30
names: Similarity
messages: Belongs to the RutC family.

1144275:COCOR RS15585
gene id: 1144275:COCOR_RS15585
uniprot id: H8MF18
names: Similarity
messages: Belongs to the AHA1 family.

1144275:COCOR RS17725
gene id: 1144275:COCOR_RS17725
uniprot id: H8MLY1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1144275:COCOR RS30165
gene id: 1144275:COCOR_RS30165
uniprot id: H8ML07
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1144275:COCOR RS14940
gene id: 1144275:COCOR_RS14940
uniprot id: H8N0B5
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

1144275:COCOR RS32215
gene id: 1144275:COCOR_RS32215
uniprot id: H8MT00
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS00625
gene id: 1144275:COCOR_RS00625
uniprot id: H8MUZ2
names: Similarity
messages: Belongs to the peptidase S8 family.

1144275:COCOR RS05465
gene id: 1144275:COCOR_RS05465
uniprot id: H8MP58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1144275:COCOR RS13485
gene id: 1144275:COCOR_RS13485
uniprot id: H8MU07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1144275:COCOR RS10325
gene id: 1144275:COCOR_RS10325
uniprot id: H8MIX3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1144275:COCOR RS00720
gene id: 1144275:COCOR_RS00720
uniprot id: H8MV09
names: Similarity
messages: Belongs to the YciI family.

1144275:COCOR RS24965
gene id: 1144275:COCOR_RS24965
uniprot id: H8MPW9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1144275:COCOR RS22015
gene id: 1144275:COCOR_RS22015
uniprot id: H8MF89
names: Similarity
messages: Belongs to the peptidase S1B family.

1144275:COCOR RS06700
gene id: 1144275:COCOR_RS06700
uniprot id: H8MTL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1144275:COCOR RS24975
gene id: 1144275:COCOR_RS24975
uniprot id: H8MPX1
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1144275:COCOR RS20990
gene id: 1144275:COCOR_RS20990
uniprot id: H8MYX0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1144275:COCOR RS17885
gene id: 1144275:COCOR_RS17885
uniprot id: H8MM12
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1144275:COCOR RS13365
gene id: 1144275:COCOR_RS13365
uniprot id: H8MTY7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS07290
gene id: 1144275:COCOR_RS07290
uniprot id: H8MVA9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1144275:COCOR RS15205
gene id: 1144275:COCOR_RS15205
uniprot id: H8N1M5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1144275:COCOR RS00825
gene id: 1144275:COCOR_RS00825
uniprot id: H8MV30
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1144275:COCOR RS25360
gene id: 1144275:COCOR_RS25360
uniprot id: H8MR99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1144275:COCOR RS43840
gene id: 1144275:COCOR_RS43840
uniprot id: H8MXL0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144275:COCOR RS23965
gene id: 1144275:COCOR_RS23965
uniprot id: H8MKW8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS41485
gene id: 1144275:COCOR_RS41485
uniprot id: H8MQS5
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Monomer.

1144275:COCOR RS21650
gene id: 1144275:COCOR_RS21650
uniprot id: H8N1U5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

1144275:COCOR RS26250
gene id: 1144275:COCOR_RS26250
uniprot id: H8MUD2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1144275:COCOR RS10180
gene id: 1144275:COCOR_RS10180
uniprot id: H8MHP4
names: Similarity
messages: Belongs to the BolA/IbaG family.

1144275:COCOR RS32025
gene id: 1144275:COCOR_RS32025
uniprot id: H8MRM7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1144275:COCOR RS18590
gene id: 1144275:COCOR_RS18590
uniprot id: H8MPQ1
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

1144275:COCOR RS08030
gene id: 1144275:COCOR_RS08030
uniprot id: H8MYG4
names: Similarity
messages: Belongs to the GST superfamily.

1144275:COCOR RS23840
gene id: 1144275:COCOR_RS23840
uniprot id: H8MKU4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144275:COCOR RS24310
gene id: 1144275:COCOR_RS24310
uniprot id: H8MM87
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1144275:COCOR RS33875
gene id: 1144275:COCOR_RS33875
uniprot id: H8MZE6
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

1144275:COCOR RS39240
gene id: 1144275:COCOR_RS39240
uniprot id: H8MWB3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1144275:COCOR RS23350
gene id: 1144275:COCOR_RS23350
uniprot id: H8MJE8
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1144275:COCOR RS06230
gene id: 1144275:COCOR_RS06230
uniprot id: H8MQQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1144275:COCOR RS11530
gene id: 1144275:COCOR_RS11530
uniprot id: H8MN14
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

1144275:COCOR RS06890
gene id: 1144275:COCOR_RS06890
uniprot id: H8MTQ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

1144275:COCOR RS27660
gene id: 1144275:COCOR_RS27660
uniprot id: H8N0N6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1144275:COCOR RS13535
gene id: 1144275:COCOR_RS13535
uniprot id: H8MVE8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS39930
gene id: 1144275:COCOR_RS39930
uniprot id: H8MY30
names: Similarity
messages: Belongs to the TPP enzyme family.

1144275:COCOR RS18585
gene id: 1144275:COCOR_RS18585
uniprot id: H8MPQ0
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1144275:COCOR RS31420
gene id: 1144275:COCOR_RS31420
uniprot id: H8MQ55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

1144275:COCOR RS16150
gene id: 1144275:COCOR_RS16150
uniprot id: H8MGH2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1144275:COCOR RS17500
gene id: 1144275:COCOR_RS17500
uniprot id: H8MKN4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS21115
gene id: 1144275:COCOR_RS21115
uniprot id: H8MYZ4
names: Similarity
messages: Belongs to the peptidase S26 family.

1144275:COCOR RS34970
gene id: 1144275:COCOR_RS34970
uniprot id: H8MFS4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).

1144275:COCOR RS37960
gene id: 1144275:COCOR_RS37960
uniprot id: H8MQG7
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1144275:COCOR RS01440
gene id: 1144275:COCOR_RS01440
uniprot id: H8MY54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1144275:COCOR RS21595
gene id: 1144275:COCOR_RS21595
uniprot id: H8N0M6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144275:COCOR RS17795
gene id: 1144275:COCOR_RS17795
uniprot id: H8MLZ5
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1144275:COCOR RS10450
gene id: 1144275:COCOR_RS10450
uniprot id: H8MIZ8
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS14965
gene id: 1144275:COCOR_RS14965
uniprot id: H8N0C1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1144275:COCOR RS38995
gene id: 1144275:COCOR_RS38995
uniprot id: H8MUT3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1144275:COCOR RS39995
gene id: 1144275:COCOR_RS39995
uniprot id: H8MY43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

1144275:COCOR RS16615
gene id: 1144275:COCOR_RS16615
uniprot id: H8MHW3
names: Similarity
messages: Belongs to the ketopantoate reductase family.

1144275:COCOR RS22480
gene id: 1144275:COCOR_RS22480
uniprot id: H8MGM3
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1144275:COCOR RS26920
gene id: 1144275:COCOR_RS26920
uniprot id: H8MXH2
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1144275:COCOR RS28230
gene id: 1144275:COCOR_RS28230
uniprot id: H8N261
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

1144275:COCOR RS20440
gene id: 1144275:COCOR_RS20440
uniprot id: H8MX78
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

1144275:COCOR RS18650
gene id: 1144275:COCOR_RS18650
uniprot id: H8MPR3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1144275:COCOR RS23410
gene id: 1144275:COCOR_RS23410
uniprot id: H8MJG0
names: Similarity
messages: Belongs to the threonine synthase family.

1144275:COCOR RS25335
gene id: 1144275:COCOR_RS25335
uniprot id: H8MR94
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

1144275:COCOR RS05555
gene id: 1144275:COCOR_RS05555
uniprot id: H8MP76
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1144275:COCOR RS29335
gene id: 1144275:COCOR_RS29335
uniprot id: H8MI86
names: Similarity
messages: Belongs to the peptidase M13 family.

1144275:COCOR RS24245
gene id: 1144275:COCOR_RS24245
uniprot id: H8MM74
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS18905
gene id: 1144275:COCOR_RS18905
uniprot id: H8MR10
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1144275:COCOR RS06640
gene id: 1144275:COCOR_RS06640
uniprot id: H8MS76
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1144275:COCOR RS39965
gene id: 1144275:COCOR_RS39965
uniprot id: H8MY37
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1144275:COCOR RS17760
gene id: 1144275:COCOR_RS17760
uniprot id: H8MLY8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS27670
gene id: 1144275:COCOR_RS27670
uniprot id: H8N0N8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1144275:COCOR RS25375
gene id: 1144275:COCOR_RS25375
uniprot id: H8MRA2
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

1144275:COCOR RS26980
gene id: 1144275:COCOR_RS26980
uniprot id: H8MXI4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1144275:COCOR RS36865
gene id: 1144275:COCOR_RS36865
uniprot id: H8MMK0
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1144275:COCOR RS27565
gene id: 1144275:COCOR_RS27565
uniprot id: H8MZ86
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1144275:COCOR RS02785
gene id: 1144275:COCOR_RS02785
uniprot id: H8MEM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

1144275:COCOR RS13540
gene id: 1144275:COCOR_RS13540
uniprot id: H8MVE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OprB family.
messages: Cell outer membrane

1144275:COCOR RS19870
gene id: 1144275:COCOR_RS19870
uniprot id: H8MU60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1144275:COCOR RS17440
gene id: 1144275:COCOR_RS17440
uniprot id: H8MKM2
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS36070
gene id: 1144275:COCOR_RS36070
uniprot id: H8MJT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

1144275:COCOR RS15170
gene id: 1144275:COCOR_RS15170
uniprot id: H8N1L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1144275:COCOR RS18555
gene id: 1144275:COCOR_RS18555
uniprot id: H8MPP4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS35545
gene id: 1144275:COCOR_RS35545
uniprot id: H8MH86
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS28385
gene id: 1144275:COCOR_RS28385
uniprot id: H8N292
names: Similarity
messages: Belongs to the peptidase M18 family.

1144275:COCOR RS34990
gene id: 1144275:COCOR_RS34990
uniprot id: H8MFS8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1144275:COCOR RS21085
gene id: 1144275:COCOR_RS21085
uniprot id: H8MYY9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1144275:COCOR RS32420
gene id: 1144275:COCOR_RS32420
uniprot id: H8MT41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1144275:COCOR RS35115
gene id: 1144275:COCOR_RS35115
uniprot id: H8MFV3
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS36795
gene id: 1144275:COCOR_RS36795
uniprot id: H8MLD6
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1144275:COCOR RS27830
gene id: 1144275:COCOR_RS27830
uniprot id: H8N0S1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

1144275:COCOR RS10900
gene id: 1144275:COCOR_RS10900
uniprot id: H8MKD8
names: Similarity
messages: Belongs to the YciI family.

1144275:COCOR RS12420
gene id: 1144275:COCOR_RS12420
uniprot id: H8MQU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1144275:COCOR RS37335
gene id: 1144275:COCOR_RS37335
uniprot id: H8MNZ6
names: Similarity
messages: Belongs to the AHA1 family.

1144275:COCOR RS05045
gene id: 1144275:COCOR_RS05045
uniprot id: H8MMS4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1144275:COCOR RS38100
gene id: 1144275:COCOR_RS38100
uniprot id: H8MRP7
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

1144275:COCOR RS32355
gene id: 1144275:COCOR_RS32355
uniprot id: H8MT28
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1144275:COCOR RS00280
gene id: 1144275:COCOR_RS00280
uniprot id: H8MTE9
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1144275:COCOR RS11775
gene id: 1144275:COCOR_RS11775
uniprot id: H8MN64
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1144275:COCOR RS22555
gene id: 1144275:COCOR_RS22555
uniprot id: H8MGN8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

1144275:COCOR RS12065
gene id: 1144275:COCOR_RS12065
uniprot id: H8MPH4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1144275:COCOR RS23120
gene id: 1144275:COCOR_RS23120
uniprot id: H8MI48
names: Similarity
messages: Belongs to the thioesterase family.

1144275:COCOR RS01910
gene id: 1144275:COCOR_RS01910
uniprot id: H8MZS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1144275:COCOR RS10150
gene id: 1144275:COCOR_RS10150
uniprot id: H8MHN8
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1144275:COCOR RS25020
gene id: 1144275:COCOR_RS25020
uniprot id: H8MPY0
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS11165
gene id: 1144275:COCOR_RS11165
uniprot id: H8MLP4
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS32925
gene id: 1144275:COCOR_RS32925
uniprot id: H8MW46
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS16560
gene id: 1144275:COCOR_RS16560
uniprot id: H8MHV3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Belongs to the histone H1/H5 family. HCT subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Might have a role in establishing the nucleoid structure of elementary bodies.
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1144275:COCOR RS32360
gene id: 1144275:COCOR_RS32360
uniprot id: H8MT29
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1144275:COCOR RS12490
gene id: 1144275:COCOR_RS12490
uniprot id: H8MQV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1144275:COCOR RS31395
gene id: 1144275:COCOR_RS31395
uniprot id: H8MQ50
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS30200
gene id: 1144275:COCOR_RS30200
uniprot id: H8ML10
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1144275:COCOR RS30935
gene id: 1144275:COCOR_RS30935
uniprot id: H8MNQ9
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS05240
gene id: 1144275:COCOR_RS05240
uniprot id: H8MMW3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1144275:COCOR RS11755
gene id: 1144275:COCOR_RS11755
uniprot id: H8MN60
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1144275:COCOR RS29690
gene id: 1144275:COCOR_RS29690
uniprot id: H8MJK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. Tam family.
messages: Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
messages: Cytoplasm

1144275:COCOR RS19445
gene id: 1144275:COCOR_RS19445
uniprot id: H8MSK3
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

1144275:COCOR RS13395
gene id: 1144275:COCOR_RS13395
uniprot id: H8MTZ3
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1144275:COCOR RS30140
gene id: 1144275:COCOR_RS30140
uniprot id: H8ML02
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1144275:COCOR RS35585
gene id: 1144275:COCOR_RS35585
uniprot id: H8MH94
names: Subcellular Location Annotation
messages: Cytoplasm

1144275:COCOR RS06705
gene id: 1144275:COCOR_RS06705
uniprot id: H8MTL4
names: Similarity
messages: Belongs to the CinA family.

1144275:COCOR RS28530
gene id: 1144275:COCOR_RS28530
uniprot id: H8MFI8
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

1144275:COCOR RS14170
gene id: 1144275:COCOR_RS14170
uniprot id: H8MX48
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144275:COCOR RS08905
gene id: 1144275:COCOR_RS08905
uniprot id: H8N1H7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1144275:COCOR RS26860
gene id: 1144275:COCOR_RS26860
uniprot id: H8MXG0
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1144275:COCOR RS31260
gene id: 1144275:COCOR_RS31260
uniprot id: H8MQ23
names: Similarity
messages: Belongs to the peptidase S8 family.

1144275:COCOR RS22540
gene id: 1144275:COCOR_RS22540
uniprot id: H8MGN5
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

1144275:COCOR RS03475
gene id: 1144275:COCOR_RS03475
uniprot id: H8MHB3
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS11490
gene id: 1144275:COCOR_RS11490
uniprot id: H8MN06
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1144275:COCOR RS07220
gene id: 1144275:COCOR_RS07220
uniprot id: H8MV95
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS39270
gene id: 1144275:COCOR_RS39270
uniprot id: H8MWB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1144275:COCOR RS06390
gene id: 1144275:COCOR_RS06390
uniprot id: H8MS25
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1144275:COCOR RS36175
gene id: 1144275:COCOR_RS36175
uniprot id: H8MJW1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

1144275:COCOR RS12330
gene id: 1144275:COCOR_RS12330
uniprot id: H8MQS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
messages: Cytoplasm

1144275:COCOR RS30495
gene id: 1144275:COCOR_RS30495
uniprot id: H8MMB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein.
messages: Membrane

1144275:COCOR RS32380
gene id: 1144275:COCOR_RS32380
uniprot id: H8MT33
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1144275:COCOR RS07650
gene id: 1144275:COCOR_RS07650
uniprot id: H8MWV3
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS05490
gene id: 1144275:COCOR_RS05490
uniprot id: H8MP63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1144275:COCOR RS22815
gene id: 1144275:COCOR_RS22815
uniprot id: H8MGU0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1144275:COCOR RS22130
gene id: 1144275:COCOR_RS22130
uniprot id: H8MFB3
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: Single-chain monomer with multiple functions.

1144275:COCOR RS06740
gene id: 1144275:COCOR_RS06740
uniprot id: H8MTM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1144275:COCOR RS37965
gene id: 1144275:COCOR_RS37965
uniprot id: H8MQG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1144275:COCOR RS10010
gene id: 1144275:COCOR_RS10010
uniprot id: H8MHL6
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1144275:COCOR RS20980
gene id: 1144275:COCOR_RS20980
uniprot id: H8MYW8
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1144275:COCOR RS11655
gene id: 1144275:COCOR_RS11655
uniprot id: H8MN39
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1144275:COCOR RS40970
gene id: 1144275:COCOR_RS40970
uniprot id: H8MI28
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS13145
gene id: 1144275:COCOR_RS13145
uniprot id: H8MTU3
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1144275:COCOR RS37095
gene id: 1144275:COCOR_RS37095
uniprot id: H8MMP6
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS25040
gene id: 1144275:COCOR_RS25040
uniprot id: H8MPY4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS18550
gene id: 1144275:COCOR_RS18550
uniprot id: H8MPP3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1144275:COCOR RS09460
gene id: 1144275:COCOR_RS09460
uniprot id: H8MF05
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144275:COCOR RS27685
gene id: 1144275:COCOR_RS27685
uniprot id: H8N0P1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1144275:COCOR RS24130
gene id: 1144275:COCOR_RS24130
uniprot id: H8MM51
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1144275:COCOR RS12020
gene id: 1144275:COCOR_RS12020
uniprot id: H8MPG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1144275:COCOR RS03010
gene id: 1144275:COCOR_RS03010
uniprot id: H8MES2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1144275:COCOR RS17765
gene id: 1144275:COCOR_RS17765
uniprot id: H8MLY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1144275:COCOR RS30090
gene id: 1144275:COCOR_RS30090
uniprot id: H8MKZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1144275:COCOR RS06825
gene id: 1144275:COCOR_RS06825
uniprot id: H8MTN8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1144275:COCOR RS05230
gene id: 1144275:COCOR_RS05230
uniprot id: H8MMW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1144275:COCOR RS12245
gene id: 1144275:COCOR_RS12245
uniprot id: H8MPK9
names: Similarity
messages: Belongs to the HesB/IscA family.

1144275:COCOR RS40085
gene id: 1144275:COCOR_RS40085
uniprot id: H8MZJ3
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1144275:COCOR RS07865
gene id: 1144275:COCOR_RS07865
uniprot id: H8MYD0
names: Similarity
messages: Belongs to the Dps family.

1144275:COCOR RS32875
gene id: 1144275:COCOR_RS32875
uniprot id: H8MW36
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell inner membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

1144275:COCOR RS38520
gene id: 1144275:COCOR_RS38520
uniprot id: H8MT67
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS29130
gene id: 1144275:COCOR_RS29130
uniprot id: H8MH01
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS35995
gene id: 1144275:COCOR_RS35995
uniprot id: H8MIM0
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS29780
gene id: 1144275:COCOR_RS29780
uniprot id: H8MJM7
names: Subcellular Location Annotation
messages: Cytoplasm

1144275:COCOR RS06490
gene id: 1144275:COCOR_RS06490
uniprot id: H8MS46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1144275:COCOR RS17565
gene id: 1144275:COCOR_RS17565
uniprot id: H8MKP7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144275:COCOR RS05475
gene id: 1144275:COCOR_RS05475
uniprot id: H8MP60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1144275:COCOR RS21460
gene id: 1144275:COCOR_RS21460
uniprot id: H8N0J7
names: Similarity
messages: Belongs to the peptidase M16 family.

1144275:COCOR RS30095
gene id: 1144275:COCOR_RS30095
uniprot id: H8MKZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1144275:COCOR RS37140
gene id: 1144275:COCOR_RS37140
uniprot id: H8MMQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1144275:COCOR RS18605
gene id: 1144275:COCOR_RS18605
uniprot id: H8MPQ4
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1144275:COCOR RS05990
gene id: 1144275:COCOR_RS05990
uniprot id: H8MQL1
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS25325
gene id: 1144275:COCOR_RS25325
uniprot id: H8MR92
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1144275:COCOR RS26765
gene id: 1144275:COCOR_RS26765
uniprot id: H8MW16
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1144275:COCOR RS27950
gene id: 1144275:COCOR_RS27950
uniprot id: H8N0U6
names: Similarity
messages: Belongs to the peptidase S49 family.

1144275:COCOR RS05870
gene id: 1144275:COCOR_RS05870
uniprot id: H8MQI7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

1144275:COCOR RS07495
gene id: 1144275:COCOR_RS07495
uniprot id: H8MWS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

1144275:COCOR RS30520
gene id: 1144275:COCOR_RS30520
uniprot id: H8MMC4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1144275:COCOR RS06900
gene id: 1144275:COCOR_RS06900
uniprot id: H8MTQ3
names: Similarity
messages: Belongs to the UPF0234 family.

1144275:COCOR RS02925
gene id: 1144275:COCOR_RS02925
uniprot id: H8MEQ5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1144275:COCOR RS06865
gene id: 1144275:COCOR_RS06865
uniprot id: H8MTP6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1144275:COCOR RS37175
gene id: 1144275:COCOR_RS37175
uniprot id: H8MMR2
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

1144275:COCOR RS08405
gene id: 1144275:COCOR_RS08405
uniprot id: H8N021
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS03225
gene id: 1144275:COCOR_RS03225
uniprot id: H8MG15
names: Similarity
messages: Belongs to the GSP E family.

1144275:COCOR RS00975
gene id: 1144275:COCOR_RS00975
uniprot id: H8MV59
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

1144275:COCOR RS10160
gene id: 1144275:COCOR_RS10160
uniprot id: H8MHP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1144275:COCOR RS21050
gene id: 1144275:COCOR_RS21050
uniprot id: H8MYY2
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1144275:COCOR RS30845
gene id: 1144275:COCOR_RS30845
uniprot id: H8MMI9
names: Similarity
messages: Belongs to the YkuD family.

1144275:COCOR RS06475
gene id: 1144275:COCOR_RS06475
uniprot id: H8MS43
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1144275:COCOR RS29230
gene id: 1144275:COCOR_RS29230
uniprot id: H8MH20
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1144275:COCOR RS11025
gene id: 1144275:COCOR_RS11025
uniprot id: H8MKG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1144275:COCOR RS26520
gene id: 1144275:COCOR_RS26520
uniprot id: H8MVW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1144275:COCOR RS22165
gene id: 1144275:COCOR_RS22165
uniprot id: H8MFB7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1144275:COCOR RS39115
gene id: 1144275:COCOR_RS39115
uniprot id: H8MUV7
names: Similarity
messages: Belongs to the nitroreductase family. HadB/RutE subfamily.

1144275:COCOR RS16990
gene id: 1144275:COCOR_RS16990
uniprot id: H8MJ87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1144275:COCOR RS23065
gene id: 1144275:COCOR_RS23065
uniprot id: H8MI37
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS21150
gene id: 1144275:COCOR_RS21150
uniprot id: H8MZ03
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144275:COCOR RS24155
gene id: 1144275:COCOR_RS24155
uniprot id: H8MM56
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS13240
gene id: 1144275:COCOR_RS13240
uniprot id: H8MTW2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1144275:COCOR RS15325
gene id: 1144275:COCOR_RS15325
uniprot id: H8N1P8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1144275:COCOR RS36420
gene id: 1144275:COCOR_RS36420
uniprot id: H8MK10
names: Similarity
messages: Belongs to the GSP E family.

1144275:COCOR RS23185
gene id: 1144275:COCOR_RS23185
uniprot id: H8MI61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

1144275:COCOR RS17270
gene id: 1144275:COCOR_RS17270
uniprot id: H8MKJ2
names: Similarity
messages: Belongs to the AHA1 family.

1144275:COCOR RS10215
gene id: 1144275:COCOR_RS10215
uniprot id: H8MHQ1
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

1144275:COCOR RS12185
gene id: 1144275:COCOR_RS12185
uniprot id: H8MPJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).

1144275:COCOR RS44615
gene id: 1144275:COCOR_RS44615
uniprot id: H8MLV6
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

1144275:COCOR RS33655
gene id: 1144275:COCOR_RS33655
uniprot id: H8MZA2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144275:COCOR RS12250
gene id: 1144275:COCOR_RS12250
uniprot id: H8MPL0
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

1144275:COCOR RS32090
gene id: 1144275:COCOR_RS32090
uniprot id: H8MSX4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1144275:COCOR RS35360
gene id: 1144275:COCOR_RS35360
uniprot id: H8MH50
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

1144275:COCOR RS04035
gene id: 1144275:COCOR_RS04035
uniprot id: H8MIR9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

1144275:COCOR RS36190
gene id: 1144275:COCOR_RS36190
uniprot id: H8MJW4
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1144275:COCOR RS04740
gene id: 1144275:COCOR_RS04740
uniprot id: H8MLG4
names: Similarity
messages: In the N-terminal section; belongs to the phytochrome family.

1144275:COCOR RS35780
gene id: 1144275:COCOR_RS35780
uniprot id: H8MIH7
names: Similarity
messages: Belongs to the peptidase S9C family.

1144275:COCOR RS05725
gene id: 1144275:COCOR_RS05725
uniprot id: H8MPB1
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

1144275:COCOR RS26635
gene id: 1144275:COCOR_RS26635
uniprot id: H8MVZ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1144275:COCOR RS19850
gene id: 1144275:COCOR_RS19850
uniprot id: H8MU56
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1144275:COCOR RS27665
gene id: 1144275:COCOR_RS27665
uniprot id: H8N0N7
names: Similarity
messages: Belongs to the UPF0047 family.

1144275:COCOR RS12035
gene id: 1144275:COCOR_RS12035
uniprot id: H8MPG8
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

1144275:COCOR RS23230
gene id: 1144275:COCOR_RS23230
uniprot id: H8MJC2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1144275:COCOR RS39940
gene id: 1144275:COCOR_RS39940
uniprot id: H8MY32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1144275:COCOR RS06650
gene id: 1144275:COCOR_RS06650
uniprot id: H8MS78
names: Similarity
messages: Belongs to the GST superfamily.

1144275:COCOR RS40080
gene id: 1144275:COCOR_RS40080
uniprot id: H8MZJ2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1144275:COCOR RS29610
gene id: 1144275:COCOR_RS29610
uniprot id: H8MID9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.
messages: Mitochondrion

1144275:COCOR RS12280
gene id: 1144275:COCOR_RS12280
uniprot id: H8MQR4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1144275:COCOR RS06735
gene id: 1144275:COCOR_RS06735
uniprot id: H8MTM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1144275:COCOR RS09985
gene id: 1144275:COCOR_RS09985
uniprot id: H8MHL1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1144275:COCOR RS24225
gene id: 1144275:COCOR_RS24225
uniprot id: H8MM70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1144275:COCOR RS31340
gene id: 1144275:COCOR_RS31340
uniprot id: H8MQ39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane

1144275:COCOR RS20960
gene id: 1144275:COCOR_RS20960
uniprot id: H8MYW4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1144275:COCOR RS07060
gene id: 1144275:COCOR_RS07060
uniprot id: H8MV63
names: Similarity
messages: Belongs to the AHA1 family.

1144275:COCOR RS28260
gene id: 1144275:COCOR_RS28260
uniprot id: H8N267
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm
messages: Mitochondrion

1144275:COCOR RS19395
gene id: 1144275:COCOR_RS19395
uniprot id: H8MSJ3
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

1144275:COCOR RS05180
gene id: 1144275:COCOR_RS05180
uniprot id: H8MMV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1144275:COCOR RS28015
gene id: 1144275:COCOR_RS28015
uniprot id: H8N0V9
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS13360
gene id: 1144275:COCOR_RS13360
uniprot id: H8MTY6
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1144275:COCOR RS25245
gene id: 1144275:COCOR_RS25245
uniprot id: H8MR76
names: Similarity
messages: Belongs to the DprA/Smf family.

1144275:COCOR RS31210
gene id: 1144275:COCOR_RS31210
uniprot id: H8MNW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1144275:COCOR RS28420
gene id: 1144275:COCOR_RS28420
uniprot id: H8N299
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

1144275:COCOR RS17995
gene id: 1144275:COCOR_RS17995
uniprot id: H8MN84
names: Similarity
messages: In the C-terminal section; belongs to the NRP synthetase family.

1144275:COCOR RS12240
gene id: 1144275:COCOR_RS12240
uniprot id: H8MPK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

1144275:COCOR RS03790
gene id: 1144275:COCOR_RS03790
uniprot id: H8MHH6
names: Similarity
messages: Belongs to the Dps family.

1144275:COCOR RS20285
gene id: 1144275:COCOR_RS20285
uniprot id: H8MVS2
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

1144275:COCOR RS15450
gene id: 1144275:COCOR_RS15450
uniprot id: H8N1S2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1144275:COCOR RS12105
gene id: 1144275:COCOR_RS12105
uniprot id: H8MPI2
names: Similarity
messages: Belongs to the cytochrome P450 family.

1144275:COCOR RS03925
gene id: 1144275:COCOR_RS03925
uniprot id: H8MIP7
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1144275:COCOR RS30310
gene id: 1144275:COCOR_RS30310
uniprot id: H8ML33
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1144275:COCOR RS25755
gene id: 1144275:COCOR_RS25755
uniprot id: H8MSR1
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1144275:COCOR RS24440
gene id: 1144275:COCOR_RS24440
uniprot id: H8MNG5
names: Similarity
messages: Belongs to the PhzF family.

1144275:COCOR RS35575
gene id: 1144275:COCOR_RS35575
uniprot id: H8MH92
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS39955
gene id: 1144275:COCOR_RS39955
uniprot id: H8MY35
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS11000
gene id: 1144275:COCOR_RS11000
uniprot id: H8MKF9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS15245
gene id: 1144275:COCOR_RS15245
uniprot id: H8N1N3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1144275:COCOR RS21655
gene id: 1144275:COCOR_RS21655
uniprot id: H8N1U6
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.

1144275:COCOR RS24790
gene id: 1144275:COCOR_RS24790
uniprot id: H8MNN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1144275:COCOR RS03915
gene id: 1144275:COCOR_RS03915
uniprot id: H8MIP5
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1144275:COCOR RS37550
gene id: 1144275:COCOR_RS37550
uniprot id: H8MP39
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1144275:COCOR RS26095
gene id: 1144275:COCOR_RS26095
uniprot id: H8MUA3
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1144275:COCOR RS18070
gene id: 1144275:COCOR_RS18070
uniprot id: H8MN99
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1144275:COCOR RS16660
gene id: 1144275:COCOR_RS16660
uniprot id: H8MHX2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS28695
gene id: 1144275:COCOR_RS28695
uniprot id: H8MFM0
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

1144275:COCOR RS18565
gene id: 1144275:COCOR_RS18565
uniprot id: H8MPP6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1144275:COCOR RS40160
gene id: 1144275:COCOR_RS40160
uniprot id: H8MZK9
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS16625
gene id: 1144275:COCOR_RS16625
uniprot id: H8MHW5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1144275:COCOR RS30400
gene id: 1144275:COCOR_RS30400
uniprot id: H8ML51
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1144275:COCOR RS21910
gene id: 1144275:COCOR_RS21910
uniprot id: H8N1Z8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1144275:COCOR RS05185
gene id: 1144275:COCOR_RS05185
uniprot id: H8MMV2
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS11600
gene id: 1144275:COCOR_RS11600
uniprot id: H8MN28
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1144275:COCOR RS29285
gene id: 1144275:COCOR_RS29285
uniprot id: H8MI76
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1144275:COCOR RS12665
gene id: 1144275:COCOR_RS12665
uniprot id: H8MQZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1144275:COCOR RS26680
gene id: 1144275:COCOR_RS26680
uniprot id: H8MVZ9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1144275:COCOR RS18705
gene id: 1144275:COCOR_RS18705
uniprot id: H8MPS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1144275:COCOR RS29200
gene id: 1144275:COCOR_RS29200
uniprot id: H8MH14
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

1144275:COCOR RS02710
gene id: 1144275:COCOR_RS02710
uniprot id: H8MEL2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1144275:COCOR RS12695
gene id: 1144275:COCOR_RS12695
uniprot id: H8MS81
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1144275:COCOR RS17730
gene id: 1144275:COCOR_RS17730
uniprot id: H8MLY2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1144275:COCOR RS24690
gene id: 1144275:COCOR_RS24690
uniprot id: H8MNL8
names: Similarity
messages: Belongs to the peptidase A24 family.

1144275:COCOR RS15255
gene id: 1144275:COCOR_RS15255
uniprot id: H8N1N5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1144275:COCOR RS26655
gene id: 1144275:COCOR_RS26655
uniprot id: H8MVZ4
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

1144275:COCOR RS04360
gene id: 1144275:COCOR_RS04360
uniprot id: H8MK37
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 3-HAO family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
messages: Homodimer.

1144275:COCOR RS37005
gene id: 1144275:COCOR_RS37005
uniprot id: H8MMM8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1144275:COCOR RS32265
gene id: 1144275:COCOR_RS32265
uniprot id: H8MT10
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1144275:COCOR RS25060
gene id: 1144275:COCOR_RS25060
uniprot id: H8MPY8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1144275:COCOR RS24120
gene id: 1144275:COCOR_RS24120
uniprot id: H8MM49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1144275:COCOR RS03185
gene id: 1144275:COCOR_RS03185
uniprot id: H8MG06
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1144275:COCOR RS37465
gene id: 1144275:COCOR_RS37465
uniprot id: H8MP22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1144275:COCOR RS39280
gene id: 1144275:COCOR_RS39280
uniprot id: H8MWC1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1144275:COCOR RS24685
gene id: 1144275:COCOR_RS24685
uniprot id: H8MNL7
names: Similarity
messages: Belongs to the bacterial secretin family.

1144275:COCOR RS38485
gene id: 1144275:COCOR_RS38485
uniprot id: H8MT60
names: Similarity
messages: Belongs to the peptidase S9C family.

1144275:COCOR RS11620
gene id: 1144275:COCOR_RS11620
uniprot id: H8MN32
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

1144275:COCOR RS15365
gene id: 1144275:COCOR_RS15365
uniprot id: H8N1Q6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

1144275:COCOR RS40435
gene id: 1144275:COCOR_RS40435
uniprot id: H8N143
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1144275:COCOR RS11220
gene id: 1144275:COCOR_RS11220
uniprot id: H8MLQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1144275:COCOR RS12360
gene id: 1144275:COCOR_RS12360
uniprot id: H8MQT0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1144275:COCOR RS05265
gene id: 1144275:COCOR_RS05265
uniprot id: H8MMW8
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS01920
gene id: 1144275:COCOR_RS01920
uniprot id: H8MZT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1144275:COCOR RS11760
gene id: 1144275:COCOR_RS11760
uniprot id: H8MN61
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1144275:COCOR RS15315
gene id: 1144275:COCOR_RS15315
uniprot id: H8N1P6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1144275:COCOR RS27500
gene id: 1144275:COCOR_RS27500
uniprot id: H8MZ72
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

1144275:COCOR RS33300
gene id: 1144275:COCOR_RS33300
uniprot id: H8MXP8
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

1144275:COCOR RS07830
gene id: 1144275:COCOR_RS07830
uniprot id: H8MWZ0
names: Similarity
messages: Belongs to the Gfa family.

1144275:COCOR RS25520
gene id: 1144275:COCOR_RS25520
uniprot id: H8MRD2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1144275:COCOR RS27725
gene id: 1144275:COCOR_RS27725
uniprot id: H8N0P9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1144275:COCOR RS18910
gene id: 1144275:COCOR_RS18910
uniprot id: H8MR11
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS20795
gene id: 1144275:COCOR_RS20795
uniprot id: H8MXF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

1144275:COCOR RS37420
gene id: 1144275:COCOR_RS37420
uniprot id: H8MP13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1144275:COCOR RS37325
gene id: 1144275:COCOR_RS37325
uniprot id: H8MNZ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1144275:COCOR RS26855
gene id: 1144275:COCOR_RS26855
uniprot id: H8MXF9
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

1144275:COCOR RS28245
gene id: 1144275:COCOR_RS28245
uniprot id: H8N264
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1144275:COCOR RS35210
gene id: 1144275:COCOR_RS35210
uniprot id: H8MFX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Cytoplasm

1144275:COCOR RS29145
gene id: 1144275:COCOR_RS29145
uniprot id: H8MH04
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS04975
gene id: 1144275:COCOR_RS04975
uniprot id: H8MLL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinylarginine dihydrolase family.
messages: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
messages: Homodimer.

1144275:COCOR RS19260
gene id: 1144275:COCOR_RS19260
uniprot id: H8MSG6
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1144275:COCOR RS37975
gene id: 1144275:COCOR_RS37975
uniprot id: H8MQH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1144275:COCOR RS15130
gene id: 1144275:COCOR_RS15130
uniprot id: H8N1L0
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1144275:COCOR RS29660
gene id: 1144275:COCOR_RS29660
uniprot id: H8MJK3
names: Similarity
messages: Belongs to the antibiotic N-acetyltransferase family.

1144275:COCOR RS06845
gene id: 1144275:COCOR_RS06845
uniprot id: H8MTP2
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1144275:COCOR RS19680
gene id: 1144275:COCOR_RS19680
uniprot id: H8MU22
names: Similarity
messages: Belongs to the cytochrome P450 family.

1144275:COCOR RS25745
gene id: 1144275:COCOR_RS25745
uniprot id: H8MSQ9
names: Similarity
messages: Belongs to the GARS family.

1144275:COCOR RS26185
gene id: 1144275:COCOR_RS26185
uniprot id: H8MUB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1144275:COCOR RS21610
gene id: 1144275:COCOR_RS21610
uniprot id: H8N0M9
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1144275:COCOR RS36875
gene id: 1144275:COCOR_RS36875
uniprot id: H8MMK2
names: Similarity
messages: Belongs to the group II decarboxylase family.

1144275:COCOR RS05875
gene id: 1144275:COCOR_RS05875
uniprot id: H8MQI8
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS22955
gene id: 1144275:COCOR_RS22955
uniprot id: H8MI16
names: Similarity
messages: Belongs to the DEAD box helicase family.

1144275:COCOR RS20450
gene id: 1144275:COCOR_RS20450
uniprot id: H8MX80
names: Similarity
messages: Belongs to the Gfa family.

1144275:COCOR RS37305
gene id: 1144275:COCOR_RS37305
uniprot id: H8MNZ0
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS10850
gene id: 1144275:COCOR_RS10850
uniprot id: H8MKC8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1144275:COCOR RS33635
gene id: 1144275:COCOR_RS33635
uniprot id: H8MXW6
names: Similarity
messages: Belongs to the universal stress protein A family.

1144275:COCOR RS05355
gene id: 1144275:COCOR_RS05355
uniprot id: H8MMY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1144275:COCOR RS35370
gene id: 1144275:COCOR_RS35370
uniprot id: H8MH52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1144275:COCOR RS01035
gene id: 1144275:COCOR_RS01035
uniprot id: H8MWJ4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1144275:COCOR RS23265
gene id: 1144275:COCOR_RS23265
uniprot id: H8MJC9
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

1144275:COCOR RS04815
gene id: 1144275:COCOR_RS04815
uniprot id: H8MLH9
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

1144275:COCOR RS01145
gene id: 1144275:COCOR_RS01145
uniprot id: H8MWL5
names: Similarity
messages: Belongs to the pirin family.

1144275:COCOR RS05565
gene id: 1144275:COCOR_RS05565
uniprot id: H8MP78
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1144275:COCOR RS31410
gene id: 1144275:COCOR_RS31410
uniprot id: H8MQ53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1144275:COCOR RS32260
gene id: 1144275:COCOR_RS32260
uniprot id: H8MT09
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

1144275:COCOR RS32070
gene id: 1144275:COCOR_RS32070
uniprot id: H8MSX0
names: Similarity
messages: Belongs to the cytochrome P450 family.

1144275:COCOR RS16050
gene id: 1144275:COCOR_RS16050
uniprot id: H8MGF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

1144275:COCOR RS39275
gene id: 1144275:COCOR_RS39275
uniprot id: H8MWC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell inner membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1144275:COCOR RS03025
gene id: 1144275:COCOR_RS03025
uniprot id: H8MES5
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1144275:COCOR RS36810
gene id: 1144275:COCOR_RS36810
uniprot id: H8MLD9
names: Similarity
messages: Belongs to the cytochrome c-552 family.

1144275:COCOR RS34545
gene id: 1144275:COCOR_RS34545
uniprot id: H8N2C0
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1144275:COCOR RS25660
gene id: 1144275:COCOR_RS25660
uniprot id: H8MSP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1144275:COCOR RS08855
gene id: 1144275:COCOR_RS08855
uniprot id: H8N1G7
names: Similarity
messages: Belongs to the squalene monooxygenase family.

1144275:COCOR RS22860
gene id: 1144275:COCOR_RS22860
uniprot id: H8MHZ5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1144275:COCOR RS37450
gene id: 1144275:COCOR_RS37450
uniprot id: H8MP19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1144275:COCOR RS15165
gene id: 1144275:COCOR_RS15165
uniprot id: H8N1L7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1144275:COCOR RS26965
gene id: 1144275:COCOR_RS26965
uniprot id: H8MXI1
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1144275:COCOR RS12055
gene id: 1144275:COCOR_RS12055
uniprot id: H8MPH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1144275:COCOR RS01605
gene id: 1144275:COCOR_RS01605
uniprot id: H8MY87
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1144275:COCOR RS24105
gene id: 1144275:COCOR_RS24105
uniprot id: H8MM48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1144275:COCOR RS32810
gene id: 1144275:COCOR_RS32810
uniprot id: H8MUP3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1144275:COCOR RS22640
gene id: 1144275:COCOR_RS22640
uniprot id: H8MGQ5
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1144275:COCOR RS21925
gene id: 1144275:COCOR_RS21925
uniprot id: H8N201
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1144275:COCOR RS32325
gene id: 1144275:COCOR_RS32325
uniprot id: H8MT22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1144275:COCOR RS19585
gene id: 1144275:COCOR_RS19585
uniprot id: H8MSN1
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1144275:COCOR RS05110
gene id: 1144275:COCOR_RS05110
uniprot id: H8MMT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1144275:COCOR RS27180
gene id: 1144275:COCOR_RS27180
uniprot id: H8MXM3
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS06820
gene id: 1144275:COCOR_RS06820
uniprot id: H8MTN7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1144275:COCOR RS00115
gene id: 1144275:COCOR_RS00115
uniprot id: H8MRY6
names: Similarity
messages: Belongs to the CapA family.

1144275:COCOR RS16485
gene id: 1144275:COCOR_RS16485
uniprot id: H8MHT7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS27835
gene id: 1144275:COCOR_RS27835
uniprot id: H8N0S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1144275:COCOR RS05425
gene id: 1144275:COCOR_RS05425
uniprot id: H8MN00
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

1144275:COCOR RS18015
gene id: 1144275:COCOR_RS18015
uniprot id: H8MN88
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1144275:COCOR RS07165
gene id: 1144275:COCOR_RS07165
uniprot id: H8MV84
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

1144275:COCOR RS01550
gene id: 1144275:COCOR_RS01550
uniprot id: H8MY76
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

1144275:COCOR RS28810
gene id: 1144275:COCOR_RS28810
uniprot id: H8MFP2
names: Similarity
messages: Belongs to the DEAD box helicase family.

1144275:COCOR RS24035
gene id: 1144275:COCOR_RS24035
uniprot id: H8MM34
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1144275:COCOR RS03335
gene id: 1144275:COCOR_RS03335
uniprot id: H8MG37
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1144275:COCOR RS06400
gene id: 1144275:COCOR_RS06400
uniprot id: H8MS27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1144275:COCOR RS03840
gene id: 1144275:COCOR_RS03840
uniprot id: H8MIN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1144275:COCOR RS13315
gene id: 1144275:COCOR_RS13315
uniprot id: H8MTX7
names: Similarity
messages: Belongs to the Skp family.

1144275:COCOR RS19535
gene id: 1144275:COCOR_RS19535
uniprot id: H8MSM1
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1144275:COCOR RS18525
gene id: 1144275:COCOR_RS18525
uniprot id: H8MPN8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

1144275:COCOR RS25715
gene id: 1144275:COCOR_RS25715
uniprot id: H8MSQ3
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS33405
gene id: 1144275:COCOR_RS33405
uniprot id: H8MXS0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1144275:COCOR RS11910
gene id: 1144275:COCOR_RS11910
uniprot id: H8MPE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. SOTCase family.
messages: Catalyzes the transfer of the carbamoyl group from carbamoyl phosphate to the delta-amino group of N(2)-succinyl-L-ornithine to produce N(2)-succinyl-L-citrulline. Is essential for arginine biosynthesis.
messages: Homotrimer.

1144275:COCOR RS33005
gene id: 1144275:COCOR_RS33005
uniprot id: H8MW62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1144275:COCOR RS11210
gene id: 1144275:COCOR_RS11210
uniprot id: H8MLQ2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1144275:COCOR RS17985
gene id: 1144275:COCOR_RS17985
uniprot id: H8MM32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1144275:COCOR RS37580
gene id: 1144275:COCOR_RS37580
uniprot id: H8MP45
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

1144275:COCOR RS04380
gene id: 1144275:COCOR_RS04380
uniprot id: H8MK41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0187 family.
messages: Membrane

1144275:COCOR RS23430
gene id: 1144275:COCOR_RS23430
uniprot id: H8MJG4
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1144275:COCOR RS00415
gene id: 1144275:COCOR_RS00415
uniprot id: H8MTH7
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS32080
gene id: 1144275:COCOR_RS32080
uniprot id: H8MSX2
names: Similarity
messages: Belongs to the GST superfamily.

1144275:COCOR RS28085
gene id: 1144275:COCOR_RS28085
uniprot id: H8N232
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Membrane

1144275:COCOR RS10290
gene id: 1144275:COCOR_RS10290
uniprot id: H8MIW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1144275:COCOR RS18915
gene id: 1144275:COCOR_RS18915
uniprot id: H8MR12
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1144275:COCOR RS30000
gene id: 1144275:COCOR_RS30000
uniprot id: H8MJS3
names: Similarity
messages: Belongs to the peptidase S1C family.

1144275:COCOR RS24710
gene id: 1144275:COCOR_RS24710
uniprot id: H8MNM2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1144275:COCOR RS23845
gene id: 1144275:COCOR_RS23845
uniprot id: H8MKU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1144275:COCOR RS22440
gene id: 1144275:COCOR_RS22440
uniprot id: H8MGL5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1144275:COCOR RS35230
gene id: 1144275:COCOR_RS35230
uniprot id: H8MH23
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1144275:COCOR RS31240
gene id: 1144275:COCOR_RS31240
uniprot id: H8MNX1
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS36690
gene id: 1144275:COCOR_RS36690
uniprot id: H8MLB5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1144275:COCOR RS22470
gene id: 1144275:COCOR_RS22470
uniprot id: H8MGM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1144275:COCOR RS19530
gene id: 1144275:COCOR_RS19530
uniprot id: H8MSM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1144275:COCOR RS09795
gene id: 1144275:COCOR_RS09795
uniprot id: H8MGB9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS11870
gene id: 1144275:COCOR_RS11870
uniprot id: H8MN83
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS15195
gene id: 1144275:COCOR_RS15195
uniprot id: H8N1M3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1144275:COCOR RS05120
gene id: 1144275:COCOR_RS05120
uniprot id: H8MMT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1144275:COCOR RS26190
gene id: 1144275:COCOR_RS26190
uniprot id: H8MUC0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1144275:COCOR RS08545
gene id: 1144275:COCOR_RS08545
uniprot id: H8N050
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1144275:COCOR RS24830
gene id: 1144275:COCOR_RS24830
uniprot id: H8MPU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1144275:COCOR RS17850
gene id: 1144275:COCOR_RS17850
uniprot id: H8MM06
names: Similarity
messages: Belongs to the peptidase S1C family.

1144275:COCOR RS38085
gene id: 1144275:COCOR_RS38085
uniprot id: H8MRP4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1144275:COCOR RS02940
gene id: 1144275:COCOR_RS02940
uniprot id: H8MEQ8
names: Subcellular Location Annotation
messages: Cytoplasm

1144275:COCOR RS17705
gene id: 1144275:COCOR_RS17705
uniprot id: H8MLX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1144275:COCOR RS30790
gene id: 1144275:COCOR_RS30790
uniprot id: H8MMH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1144275:COCOR RS18170
gene id: 1144275:COCOR_RS18170
uniprot id: H8MNB9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144275:COCOR RS09320
gene id: 1144275:COCOR_RS09320
uniprot id: H8MEX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1144275:COCOR RS32425
gene id: 1144275:COCOR_RS32425
uniprot id: H8MT42
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1144275:COCOR RS03990
gene id: 1144275:COCOR_RS03990
uniprot id: H8MIR0
names: Similarity
messages: Belongs to the cytochrome P450 family.

1144275:COCOR RS02120
gene id: 1144275:COCOR_RS02120
uniprot id: H8MZX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Belongs to the GtrA family.
messages: Membrane

1144275:COCOR RS30955
gene id: 1144275:COCOR_RS30955
uniprot id: H8MNR3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1144275:COCOR RS14125
gene id: 1144275:COCOR_RS14125
uniprot id: H8MX39
names: Subunit
messages: Homodimer.

1144275:COCOR RS05845
gene id: 1144275:COCOR_RS05845
uniprot id: H8MPD5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS32880
gene id: 1144275:COCOR_RS32880
uniprot id: H8MW37
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Periplasm

1144275:COCOR RS27495
gene id: 1144275:COCOR_RS27495
uniprot id: H8MZ71
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1144275:COCOR RS22420
gene id: 1144275:COCOR_RS22420
uniprot id: H8MFG5
names: Similarity
messages: Belongs to the UPF0102 family.

1144275:COCOR RS25175
gene id: 1144275:COCOR_RS25175
uniprot id: H8MQ10
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1144275:COCOR RS31180
gene id: 1144275:COCOR_RS31180
uniprot id: H8MNV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

1144275:COCOR RS04010
gene id: 1144275:COCOR_RS04010
uniprot id: H8MIR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

1144275:COCOR RS17205
gene id: 1144275:COCOR_RS17205
uniprot id: H8MKI1
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

1144275:COCOR RS30825
gene id: 1144275:COCOR_RS30825
uniprot id: H8MMI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1144275:COCOR RS21920
gene id: 1144275:COCOR_RS21920
uniprot id: H8N200
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1144275:COCOR RS18935
gene id: 1144275:COCOR_RS18935
uniprot id: H8MR16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1144275:COCOR RS44075
gene id: 1144275:COCOR_RS44075
uniprot id: H8MYX8
names: Similarity
messages: In the C-terminal section; belongs to the NRP synthetase family.

1144275:COCOR RS20480
gene id: 1144275:COCOR_RS20480
uniprot id: H8MX86
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1144275:COCOR RS15290
gene id: 1144275:COCOR_RS15290
uniprot id: H8N1P2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1144275:COCOR RS18315
gene id: 1144275:COCOR_RS18315
uniprot id: H8MNE7
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS24915
gene id: 1144275:COCOR_RS24915
uniprot id: H8MPW0
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1144275:COCOR RS11905
gene id: 1144275:COCOR_RS11905
uniprot id: H8MPE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1144275:COCOR RS18560
gene id: 1144275:COCOR_RS18560
uniprot id: H8MPP5
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1144275:COCOR RS15260
gene id: 1144275:COCOR_RS15260
uniprot id: H8N1N6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1144275:COCOR RS12835
gene id: 1144275:COCOR_RS12835
uniprot id: H8MSA8
names: Similarity
messages: Belongs to the thioesterase family.

1144275:COCOR RS37000
gene id: 1144275:COCOR_RS37000
uniprot id: H8MMM7
names: Similarity
messages: Belongs to the LEA type 2 family.

1144275:COCOR RS16930
gene id: 1144275:COCOR_RS16930
uniprot id: H8MJ75
names: Similarity
messages: Belongs to the GST superfamily.

1144275:COCOR RS23200
gene id: 1144275:COCOR_RS23200
uniprot id: H8MI64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1144275:COCOR RS22200
gene id: 1144275:COCOR_RS22200
uniprot id: H8MFC3
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

1144275:COCOR RS25260
gene id: 1144275:COCOR_RS25260
uniprot id: H8MR79
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1144275:COCOR RS31120
gene id: 1144275:COCOR_RS31120
uniprot id: H8MNU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1144275:COCOR RS09765
gene id: 1144275:COCOR_RS09765
uniprot id: H8MGB7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1144275:COCOR RS08915
gene id: 1144275:COCOR_RS08915
uniprot id: H8N1H9
names: Similarity
messages: Belongs to the asparaginase 1 family.

1144275:COCOR RS32415
gene id: 1144275:COCOR_RS32415
uniprot id: H8MT40
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1144275:COCOR RS22585
gene id: 1144275:COCOR_RS22585
uniprot id: H8MGP4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

1144275:COCOR RS30450
gene id: 1144275:COCOR_RS30450
uniprot id: H8ML60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1144275:COCOR RS05105
gene id: 1144275:COCOR_RS05105
uniprot id: H8MMT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1144275:COCOR RS34515
gene id: 1144275:COCOR_RS34515
uniprot id: H8N2B4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1144275:COCOR RS38325
gene id: 1144275:COCOR_RS38325
uniprot id: H8MRU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1144275:COCOR RS40425
gene id: 1144275:COCOR_RS40425
uniprot id: H8N141
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1144275:COCOR RS22395
gene id: 1144275:COCOR_RS22395
uniprot id: H8MFG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the encapsulin family. Family 1 subfamily.
messages: Encapsulin nanocompartment

1144275:COCOR RS06675
gene id: 1144275:COCOR_RS06675
uniprot id: H8MTK8
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Homotetramer.

1144275:COCOR RS00695
gene id: 1144275:COCOR_RS00695
uniprot id: H8MV05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1144275:COCOR RS35565
gene id: 1144275:COCOR_RS35565
uniprot id: H8MH90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1144275:COCOR RS14790
gene id: 1144275:COCOR_RS14790
uniprot id: H8N086
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

1144275:COCOR RS15285
gene id: 1144275:COCOR_RS15285
uniprot id: H8N1P1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1144275:COCOR RS32145
gene id: 1144275:COCOR_RS32145
uniprot id: H8MSY6
names: Similarity
messages: Belongs to the histone deacetylase family.

1144275:COCOR RS28095
gene id: 1144275:COCOR_RS28095
uniprot id: H8N234
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1144275:COCOR RS22630
gene id: 1144275:COCOR_RS22630
uniprot id: H8MGQ3
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1144275:COCOR RS06955
gene id: 1144275:COCOR_RS06955
uniprot id: H8MTR5
names: Function
names: Similarity
messages: Belongs to the peptidase S9A family.
messages: This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus. It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser.

1144275:COCOR RS22635
gene id: 1144275:COCOR_RS22635
uniprot id: H8MGQ4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS24220
gene id: 1144275:COCOR_RS24220
uniprot id: H8MM69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1144275:COCOR RS06355
gene id: 1144275:COCOR_RS06355
uniprot id: H8MS18
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily.

1144275:COCOR RS15540
gene id: 1144275:COCOR_RS15540
uniprot id: H8MF09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0187 family.
messages: Membrane

1144275:COCOR RS38935
gene id: 1144275:COCOR_RS38935
uniprot id: H8MUS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1144275:COCOR RS23425
gene id: 1144275:COCOR_RS23425
uniprot id: H8MJG3
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

1144275:COCOR RS22740
gene id: 1144275:COCOR_RS22740
uniprot id: H8MGS5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144275:COCOR RS34965
gene id: 1144275:COCOR_RS34965
uniprot id: H8MFS3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Monomer.

1144275:COCOR RS24970
gene id: 1144275:COCOR_RS24970
uniprot id: H8MPX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1144275:COCOR RS32775
gene id: 1144275:COCOR_RS32775
uniprot id: H8MUN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1144275:COCOR RS03390
gene id: 1144275:COCOR_RS03390
uniprot id: H8MG46
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS32625
gene id: 1144275:COCOR_RS32625
uniprot id: H8MUK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

1144275:COCOR RS28455
gene id: 1144275:COCOR_RS28455
uniprot id: H8MFH2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1144275:COCOR RS04880
gene id: 1144275:COCOR_RS04880
uniprot id: H8MLJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

1144275:COCOR RS05215
gene id: 1144275:COCOR_RS05215
uniprot id: H8MMV8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1144275:COCOR RS17845
gene id: 1144275:COCOR_RS17845
uniprot id: H8MM05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1144275:COCOR RS04060
gene id: 1144275:COCOR_RS04060
uniprot id: H8MIS4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1144275:COCOR RS15190
gene id: 1144275:COCOR_RS15190
uniprot id: H8N1M2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1144275:COCOR RS08625
gene id: 1144275:COCOR_RS08625
uniprot id: H8N066
names: Cofactor
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group I subfamily.
messages: Binds 1 heme group per subunit.

1144275:COCOR RS31910
gene id: 1144275:COCOR_RS31910
uniprot id: H8MRK5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1144275:COCOR RS12635
gene id: 1144275:COCOR_RS12635
uniprot id: H8MQY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1144275:COCOR RS17445
gene id: 1144275:COCOR_RS17445
uniprot id: H8MKM3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1144275:COCOR RS17315
gene id: 1144275:COCOR_RS17315
uniprot id: H8MKK1
names: Similarity
messages: Belongs to the arginase family.

1144275:COCOR RS34770
gene id: 1144275:COCOR_RS34770
uniprot id: H8N2G6
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

1144275:COCOR RS29710
gene id: 1144275:COCOR_RS29710
uniprot id: H8MJL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1144275:COCOR RS12355
gene id: 1144275:COCOR_RS12355
uniprot id: H8MQS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1144275:COCOR RS03945
gene id: 1144275:COCOR_RS03945
uniprot id: H8MIQ1
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS33035
gene id: 1144275:COCOR_RS33035
uniprot id: H8MW68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

1144275:COCOR RS31080
gene id: 1144275:COCOR_RS31080
uniprot id: H8MNT9
names: Similarity
messages: Belongs to the peptidase S16 family.

1144275:COCOR RS13025
gene id: 1144275:COCOR_RS13025
uniprot id: H8MSE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

1144275:COCOR RS18655
gene id: 1144275:COCOR_RS18655
uniprot id: H8MPR4
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1144275:COCOR RS22660
gene id: 1144275:COCOR_RS22660
uniprot id: H8MGQ9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

1144275:COCOR RS12085
gene id: 1144275:COCOR_RS12085
uniprot id: H8MPH8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS11880
gene id: 1144275:COCOR_RS11880
uniprot id: H8MPD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1144275:COCOR RS18775
gene id: 1144275:COCOR_RS18775
uniprot id: H8MPT9
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS11080
gene id: 1144275:COCOR_RS11080
uniprot id: H8MLM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1144275:COCOR RS12265
gene id: 1144275:COCOR_RS12265
uniprot id: H8MPL3
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS12410
gene id: 1144275:COCOR_RS12410
uniprot id: H8MQU0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1144275:COCOR RS07245
gene id: 1144275:COCOR_RS07245
uniprot id: H8MVA0
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

1144275:COCOR RS14985
gene id: 1144275:COCOR_RS14985
uniprot id: H8N0C5
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS29620
gene id: 1144275:COCOR_RS29620
uniprot id: H8MIE1
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS10800
gene id: 1144275:COCOR_RS10800
uniprot id: H8MKB8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1144275:COCOR RS37585
gene id: 1144275:COCOR_RS37585
uniprot id: H8MP46
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS22750
gene id: 1144275:COCOR_RS22750
uniprot id: H8MGS7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1144275:COCOR RS01555
gene id: 1144275:COCOR_RS01555
uniprot id: H8MY77
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

1144275:COCOR RS22450
gene id: 1144275:COCOR_RS22450
uniprot id: H8MGL7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1144275:COCOR RS25355
gene id: 1144275:COCOR_RS25355
uniprot id: H8MR98
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1144275:COCOR RS13090
gene id: 1144275:COCOR_RS13090
uniprot id: H8MSF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1144275:COCOR RS17750
gene id: 1144275:COCOR_RS17750
uniprot id: H8MLY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1144275:COCOR RS25185
gene id: 1144275:COCOR_RS25185
uniprot id: H8MQ12
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1144275:COCOR RS19155
gene id: 1144275:COCOR_RS19155
uniprot id: H8MR62
names: Similarity
messages: Belongs to the AlaDH/PNT family.

1144275:COCOR RS29345
gene id: 1144275:COCOR_RS29345
uniprot id: H8MI88
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144275:COCOR RS00290
gene id: 1144275:COCOR_RS00290
uniprot id: H8MTF1
names: Subcellular Location Annotation
messages: Cytoplasm

1144275:COCOR RS25680
gene id: 1144275:COCOR_RS25680
uniprot id: H8MSP6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS24785
gene id: 1144275:COCOR_RS24785
uniprot id: H8MNN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1144275:COCOR RS19275
gene id: 1144275:COCOR_RS19275
uniprot id: H8MSG9
names: Similarity
messages: Belongs to the D-alanine--D-alanine ligase family.

1144275:COCOR RS11185
gene id: 1144275:COCOR_RS11185
uniprot id: H8MLP8
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1144275:COCOR RS25590
gene id: 1144275:COCOR_RS25590
uniprot id: H8MRE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1144275:COCOR RS06360
gene id: 1144275:COCOR_RS06360
uniprot id: H8MS19
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

1144275:COCOR RS27445
gene id: 1144275:COCOR_RS27445
uniprot id: H8MZ60
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144275:COCOR RS08525
gene id: 1144275:COCOR_RS08525
uniprot id: H8N046
names: Similarity
messages: Belongs to the peptidase S51 family.

1144275:COCOR RS39950
gene id: 1144275:COCOR_RS39950
uniprot id: H8MY34
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS12010
gene id: 1144275:COCOR_RS12010
uniprot id: H8MPG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1144275:COCOR RS25165
gene id: 1144275:COCOR_RS25165
uniprot id: H8MQ08
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1144275:COCOR RS29980
gene id: 1144275:COCOR_RS29980
uniprot id: H8MJR9
names: Similarity
messages: Belongs to the thioredoxin family.

1144275:COCOR RS11085
gene id: 1144275:COCOR_RS11085
uniprot id: H8MLM8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS13110
gene id: 1144275:COCOR_RS13110
uniprot id: H8MTT6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1144275:COCOR RS06860
gene id: 1144275:COCOR_RS06860
uniprot id: H8MTP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1144275:COCOR RS06540
gene id: 1144275:COCOR_RS06540
uniprot id: H8MS56
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1144275:COCOR RS03480
gene id: 1144275:COCOR_RS03480
uniprot id: H8MHB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1144275:COCOR RS12435
gene id: 1144275:COCOR_RS12435
uniprot id: H8MQU5
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1144275:COCOR RS05285
gene id: 1144275:COCOR_RS05285
uniprot id: H8MMX2
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS17785
gene id: 1144275:COCOR_RS17785
uniprot id: H8MLZ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

1144275:COCOR RS21040
gene id: 1144275:COCOR_RS21040
uniprot id: H8MYY0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1144275:COCOR RS24650
gene id: 1144275:COCOR_RS24650
uniprot id: H8MNL0
names: Subcellular Location Annotation
messages: Cytoplasm

1144275:COCOR RS30265
gene id: 1144275:COCOR_RS30265
uniprot id: H8ML23
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1144275:COCOR RS06275
gene id: 1144275:COCOR_RS06275
uniprot id: H8MS02
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1144275:COCOR RS09740
gene id: 1144275:COCOR_RS09740
uniprot id: H8MGB2
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1144275:COCOR RS24455
gene id: 1144275:COCOR_RS24455
uniprot id: H8MNG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1144275:COCOR RS12845
gene id: 1144275:COCOR_RS12845
uniprot id: H8MSB0
names: Similarity
messages: Belongs to the thioesterase family.

1144275:COCOR RS29945
gene id: 1144275:COCOR_RS29945
uniprot id: H8MJR2
names: Similarity
messages: Belongs to the peptidase M16 family.

1144275:COCOR RS28110
gene id: 1144275:COCOR_RS28110
uniprot id: H8N237
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1144275:COCOR RS10075
gene id: 1144275:COCOR_RS10075
uniprot id: H8MHM9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1144275:COCOR RS38800
gene id: 1144275:COCOR_RS38800
uniprot id: H8MTC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

1144275:COCOR RS14025
gene id: 1144275:COCOR_RS14025
uniprot id: H8MX19
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144275:COCOR RS26260
gene id: 1144275:COCOR_RS26260
uniprot id: H8MUD4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS25400
gene id: 1144275:COCOR_RS25400
uniprot id: H8MRA7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1144275:COCOR RS14655
gene id: 1144275:COCOR_RS14655
uniprot id: H8MYS7
names: Similarity
messages: Belongs to the PhoH family.

1144275:COCOR RS26265
gene id: 1144275:COCOR_RS26265
uniprot id: H8MUD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

1144275:COCOR RS02035
gene id: 1144275:COCOR_RS02035
uniprot id: H8MZV4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1144275:COCOR RS33675
gene id: 1144275:COCOR_RS33675
uniprot id: H8MZA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1144275:COCOR RS11485
gene id: 1144275:COCOR_RS11485
uniprot id: H8MN05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1144275:COCOR RS05175
gene id: 1144275:COCOR_RS05175
uniprot id: H8MMV0
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

1144275:COCOR RS01720
gene id: 1144275:COCOR_RS01720
uniprot id: H8MYB0
names: Similarity
messages: Belongs to the pirin family.

1144275:COCOR RS03635
gene id: 1144275:COCOR_RS03635
uniprot id: H8MHE5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144275:COCOR RS02670
gene id: 1144275:COCOR_RS02670
uniprot id: H8MEK4
names: Similarity
messages: Belongs to the neutral ceramidase family.

1144275:COCOR RS06470
gene id: 1144275:COCOR_RS06470
uniprot id: H8MS42
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS06720
gene id: 1144275:COCOR_RS06720
uniprot id: H8MTL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1144275:COCOR RS05130
gene id: 1144275:COCOR_RS05130
uniprot id: H8MMU1
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1144275:COCOR RS34960
gene id: 1144275:COCOR_RS34960
uniprot id: H8MFS2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Monomer.

1144275:COCOR RS38330
gene id: 1144275:COCOR_RS38330
uniprot id: H8MRU3
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1144275:COCOR RS12200
gene id: 1144275:COCOR_RS12200
uniprot id: H8MPK1
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.

1144275:COCOR RS15265
gene id: 1144275:COCOR_RS15265
uniprot id: H8N1N7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1144275:COCOR RS20035
gene id: 1144275:COCOR_RS20035
uniprot id: H8MVM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1144275:COCOR RS04065
gene id: 1144275:COCOR_RS04065
uniprot id: H8MIS5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144275:COCOR RS30675
gene id: 1144275:COCOR_RS30675
uniprot id: H8MMF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Membrane

1144275:COCOR RS08845
gene id: 1144275:COCOR_RS08845
uniprot id: H8N1G5
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS26780
gene id: 1144275:COCOR_RS26780
uniprot id: H8MW19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1144275:COCOR RS19590
gene id: 1144275:COCOR_RS19590
uniprot id: H8MSN2
names: Similarity
messages: Belongs to the YciI family.

1144275:COCOR RS36380
gene id: 1144275:COCOR_RS36380
uniprot id: H8MK02
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1144275:COCOR RS20970
gene id: 1144275:COCOR_RS20970
uniprot id: H8MYW6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1144275:COCOR RS39040
gene id: 1144275:COCOR_RS39040
uniprot id: H8MUU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1144275:COCOR RS25740
gene id: 1144275:COCOR_RS25740
uniprot id: H8MSQ8
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS25640
gene id: 1144275:COCOR_RS25640
uniprot id: H8MSP0
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1144275:COCOR RS30040
gene id: 1144275:COCOR_RS30040
uniprot id: H8MJT1
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1144275:COCOR RS35220
gene id: 1144275:COCOR_RS35220
uniprot id: H8MFX4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1144275:COCOR RS31680
gene id: 1144275:COCOR_RS31680
uniprot id: H8MRF9
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1144275:COCOR RS13055
gene id: 1144275:COCOR_RS13055
uniprot id: H8MSE8
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS23395
gene id: 1144275:COCOR_RS23395
uniprot id: H8MJF7
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1144275:COCOR RS13225
gene id: 1144275:COCOR_RS13225
uniprot id: H8MTV9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS12625
gene id: 1144275:COCOR_RS12625
uniprot id: H8MQY2
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

1144275:COCOR RS10185
gene id: 1144275:COCOR_RS10185
uniprot id: H8MHP5
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

1144275:COCOR RS18345
gene id: 1144275:COCOR_RS18345
uniprot id: H8MNF2
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1144275:COCOR RS10035
gene id: 1144275:COCOR_RS10035
uniprot id: H8MHM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1144275:COCOR RS27490
gene id: 1144275:COCOR_RS27490
uniprot id: H8MZ70
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144275:COCOR RS12820
gene id: 1144275:COCOR_RS12820
uniprot id: H8MSA5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1144275:COCOR RS01260
gene id: 1144275:COCOR_RS01260
uniprot id: H8MWN8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1144275:COCOR RS28225
gene id: 1144275:COCOR_RS28225
uniprot id: H8N260
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

1144275:COCOR RS12670
gene id: 1144275:COCOR_RS12670
uniprot id: H8MQZ1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1144275:COCOR RS13005
gene id: 1144275:COCOR_RS13005
uniprot id: H8MSD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1144275:COCOR RS23650
gene id: 1144275:COCOR_RS23650
uniprot id: H8MKQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell inner membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1144275:COCOR RS06960
gene id: 1144275:COCOR_RS06960
uniprot id: H8MTR6
names: Similarity
messages: Belongs to the Gfa family.

1144275:COCOR RS24715
gene id: 1144275:COCOR_RS24715
uniprot id: H8MNM3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1144275:COCOR RS22485
gene id: 1144275:COCOR_RS22485
uniprot id: H8MGM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

1144275:COCOR RS35125
gene id: 1144275:COCOR_RS35125
uniprot id: H8MFV5
names: Cofactor
messages: Can also use Mn(2+) ion.

1144275:COCOR RS21025
gene id: 1144275:COCOR_RS21025
uniprot id: H8MYX7
names: Similarity
messages: In the C-terminal section; belongs to the NRP synthetase family.

1144275:COCOR RS17940
gene id: 1144275:COCOR_RS17940
uniprot id: H8MM23
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1144275:COCOR RS30635
gene id: 1144275:COCOR_RS30635
uniprot id: H8MME7
names: Similarity
messages: Belongs to the acylphosphatase family.

1144275:COCOR RS19735
gene id: 1144275:COCOR_RS19735
uniprot id: H8MU33
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS21020
gene id: 1144275:COCOR_RS21020
uniprot id: H8MYX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1144275:COCOR RS10820
gene id: 1144275:COCOR_RS10820
uniprot id: H8MKC2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1144275:COCOR RS38120
gene id: 1144275:COCOR_RS38120
uniprot id: H8MRQ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1144275:COCOR RS04245
gene id: 1144275:COCOR_RS04245
uniprot id: H8MK14
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

1144275:COCOR RS35445
gene id: 1144275:COCOR_RS35445
uniprot id: H8MH66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1144275:COCOR RS06595
gene id: 1144275:COCOR_RS06595
uniprot id: H8MS67
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1144275:COCOR RS10060
gene id: 1144275:COCOR_RS10060
uniprot id: H8MHM6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

1144275:COCOR RS31105
gene id: 1144275:COCOR_RS31105
uniprot id: H8MNU4
names: Similarity
messages: Belongs to the tRNA(His) guanylyltransferase family.

1144275:COCOR RS21705
gene id: 1144275:COCOR_RS21705
uniprot id: H8N1V6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1144275:COCOR RS37505
gene id: 1144275:COCOR_RS37505
uniprot id: H8MP30
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1144275:COCOR RS40075
gene id: 1144275:COCOR_RS40075
uniprot id: H8MZJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1144275:COCOR RS36530
gene id: 1144275:COCOR_RS36530
uniprot id: H8ML83
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

1144275:COCOR RS25525
gene id: 1144275:COCOR_RS25525
uniprot id: H8MRD3
names: Similarity
messages: Belongs to the CFA/CMAS family.

1144275:COCOR RS18425
gene id: 1144275:COCOR_RS18425
uniprot id: H8MPL8
names: Similarity
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.

1144275:COCOR RS25470
gene id: 1144275:COCOR_RS25470
uniprot id: H8MRC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1144275:COCOR RS24825
gene id: 1144275:COCOR_RS24825
uniprot id: H8MNP4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1144275:COCOR RS09885
gene id: 1144275:COCOR_RS09885
uniprot id: H8MHJ1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1144275:COCOR RS31555
gene id: 1144275:COCOR_RS31555
uniprot id: H8MQ83
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).

1144275:COCOR RS27800
gene id: 1144275:COCOR_RS27800
uniprot id: H8N0R5
names: Similarity
messages: Belongs to the peptidase U62 family.

1144275:COCOR RS23225
gene id: 1144275:COCOR_RS23225
uniprot id: H8MJC1
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1144275:COCOR RS27525
gene id: 1144275:COCOR_RS27525
uniprot id: H8MZ77
names: Similarity
messages: Belongs to the RNase T2 family.

1144275:COCOR RS13300
gene id: 1144275:COCOR_RS13300
uniprot id: H8MTX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1144275:COCOR RS20675
gene id: 1144275:COCOR_RS20675
uniprot id: H8MXC6
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1144275:COCOR RS11675
gene id: 1144275:COCOR_RS11675
uniprot id: H8MN43
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1144275:COCOR RS10815
gene id: 1144275:COCOR_RS10815
uniprot id: H8MKC1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1144275:COCOR RS05710
gene id: 1144275:COCOR_RS05710
uniprot id: H8MPA8
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.
messages: In the C-terminal section; belongs to the trehalose phosphatase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 20 family.

1144275:COCOR RS08135
gene id: 1144275:COCOR_RS08135
uniprot id: H8MYI6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1144275:COCOR RS07715
gene id: 1144275:COCOR_RS07715
uniprot id: H8MWW7
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1144275:COCOR RS09560
gene id: 1144275:COCOR_RS09560
uniprot id: H8MG75
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1144275:COCOR RS39960
gene id: 1144275:COCOR_RS39960
uniprot id: H8MY36
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1144275:COCOR RS03910
gene id: 1144275:COCOR_RS03910
uniprot id: H8MIP4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1144275:COCOR RS16075
gene id: 1144275:COCOR_RS16075
uniprot id: H8MGF6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1144275:COCOR RS42770
gene id: 1144275:COCOR_RS42770
uniprot id: H8MZ67
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

1144275:COCOR RS04350
gene id: 1144275:COCOR_RS04350
uniprot id: H8MK35
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS31150
gene id: 1144275:COCOR_RS31150
uniprot id: H8MNV3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1144275:COCOR RS07870
gene id: 1144275:COCOR_RS07870
uniprot id: H8MYD1
names: Function
names: Similarity
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.

1144275:COCOR RS05300
gene id: 1144275:COCOR_RS05300
uniprot id: H8MMX5
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

1144275:COCOR RS15970
gene id: 1144275:COCOR_RS15970
uniprot id: H8MGD6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1144275:COCOR RS21900
gene id: 1144275:COCOR_RS21900
uniprot id: H8N1Z6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1144275:COCOR RS24145
gene id: 1144275:COCOR_RS24145
uniprot id: H8MM54
names: Similarity
messages: Belongs to the LOG family.

1144275:COCOR RS05430
gene id: 1144275:COCOR_RS05430
uniprot id: H8MN01
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

1144275:COCOR RS14425
gene id: 1144275:COCOR_RS14425
uniprot id: H8MYN3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1144275:COCOR RS32910
gene id: 1144275:COCOR_RS32910
uniprot id: H8MW43
names: Similarity
messages: Belongs to the peptidase S8 family.

1144275:COCOR RS36885
gene id: 1144275:COCOR_RS36885
uniprot id: H8MMK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1144275:COCOR RS05560
gene id: 1144275:COCOR_RS05560
uniprot id: H8MP77
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1144275:COCOR RS17775
gene id: 1144275:COCOR_RS17775
uniprot id: H8MLZ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

1144275:COCOR RS30145
gene id: 1144275:COCOR_RS30145
uniprot id: H8ML03
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1144275:COCOR RS11175
gene id: 1144275:COCOR_RS11175
uniprot id: H8MLP6
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1144275:COCOR RS18025
gene id: 1144275:COCOR_RS18025
uniprot id: H8MN90
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.

1144275:COCOR RS28515
gene id: 1144275:COCOR_RS28515
uniprot id: H8MFI5
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS40020
gene id: 1144275:COCOR_RS40020
uniprot id: H8MZI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1144275:COCOR RS38055
gene id: 1144275:COCOR_RS38055
uniprot id: H8MRN8
names: Similarity
messages: Belongs to the glyoxalase I family.

1144275:COCOR RS03395
gene id: 1144275:COCOR_RS03395
uniprot id: H8MG47
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1144275:COCOR RS01860
gene id: 1144275:COCOR_RS01860
uniprot id: H8MZR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1144275:COCOR RS22895
gene id: 1144275:COCOR_RS22895
uniprot id: H8MI02
names: Subcellular Location Annotation
messages: Secreted

1144275:COCOR RS02055
gene id: 1144275:COCOR_RS02055
uniprot id: H8MZV8
names: Similarity
messages: Belongs to the band 7/mec-2 family.

1144275:COCOR RS01600
gene id: 1144275:COCOR_RS01600
uniprot id: H8MY86
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1144275:COCOR RS07755
gene id: 1144275:COCOR_RS07755
uniprot id: H8MWX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1144275:COCOR RS24405
gene id: 1144275:COCOR_RS24405
uniprot id: H8MMA6
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1144275:COCOR RS37615
gene id: 1144275:COCOR_RS37615
uniprot id: H8MP52
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1144275:COCOR RS09370
gene id: 1144275:COCOR_RS09370
uniprot id: H8MEY8
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

1144275:COCOR RS31700
gene id: 1144275:COCOR_RS31700
uniprot id: H8MRG3
names: Subcellular Location Annotation
messages: Cytoplasm

1144275:COCOR RS30455
gene id: 1144275:COCOR_RS30455
uniprot id: H8ML61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1144275:COCOR RS27865
gene id: 1144275:COCOR_RS27865
uniprot id: H8N0S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

1144275:COCOR RS22690
gene id: 1144275:COCOR_RS22690
uniprot id: H8MGR5
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1144275:COCOR RS30920
gene id: 1144275:COCOR_RS30920
uniprot id: H8MNQ6
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

1144275:COCOR RS36230
gene id: 1144275:COCOR_RS36230
uniprot id: H8MJX2
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS13515
gene id: 1144275:COCOR_RS13515
uniprot id: H8MVE4
names: Similarity
messages: Belongs to the RecJ family.

1144275:COCOR RS05825
gene id: 1144275:COCOR_RS05825
uniprot id: H8MPD1
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1144275:COCOR RS07980
gene id: 1144275:COCOR_RS07980
uniprot id: H8MYF4
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1144275:COCOR RS21205
gene id: 1144275:COCOR_RS21205
uniprot id: H8MZ15
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1144275:COCOR RS33080
gene id: 1144275:COCOR_RS33080
uniprot id: H8MW77
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

1144275:COCOR RS10955
gene id: 1144275:COCOR_RS10955
uniprot id: H8MKE9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

1144275:COCOR RS26450
gene id: 1144275:COCOR_RS26450
uniprot id: H8MVV3
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS04545
gene id: 1144275:COCOR_RS04545
uniprot id: H8MK75
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1144275:COCOR RS27510
gene id: 1144275:COCOR_RS27510
uniprot id: H8MZ74
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1144275:COCOR RS40300
gene id: 1144275:COCOR_RS40300
uniprot id: H8MZN7
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

1144275:COCOR RS36350
gene id: 1144275:COCOR_RS36350
uniprot id: H8MJZ6
names: Similarity
messages: Belongs to the LarC family.

1144275:COCOR RS16805
gene id: 1144275:COCOR_RS16805
uniprot id: H8MJ50
names: Similarity
messages: Belongs to the AHA1 family.

1144275:COCOR RS22365
gene id: 1144275:COCOR_RS22365
uniprot id: H8MFF6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144275:COCOR RS36985
gene id: 1144275:COCOR_RS36985
uniprot id: H8MMM4
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS02835
gene id: 1144275:COCOR_RS02835
uniprot id: H8MEN7
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1144275:COCOR RS04665
gene id: 1144275:COCOR_RS04665
uniprot id: H8MLE9
names: Similarity
messages: Belongs to the pirin family.

1144275:COCOR RS27455
gene id: 1144275:COCOR_RS27455
uniprot id: H8MZ62
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144275:COCOR RS35375
gene id: 1144275:COCOR_RS35375
uniprot id: H8MH53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

1144275:COCOR RS14900
gene id: 1144275:COCOR_RS14900
uniprot id: H8N0A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1144275:COCOR RS34950
gene id: 1144275:COCOR_RS34950
uniprot id: H8MFS0
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1144275:COCOR RS05115
gene id: 1144275:COCOR_RS05115
uniprot id: H8MMT8
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS00755
gene id: 1144275:COCOR_RS00755
uniprot id: H8MV16
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Maintains high levels of reduced glutathione.

1144275:COCOR RS11305
gene id: 1144275:COCOR_RS11305
uniprot id: H8MLS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

1144275:COCOR RS36790
gene id: 1144275:COCOR_RS36790
uniprot id: H8MLD5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS14480
gene id: 1144275:COCOR_RS14480
uniprot id: H8MYP4
names: Similarity
messages: Belongs to the aldose epimerase family.

1144275:COCOR RS27030
gene id: 1144275:COCOR_RS27030
uniprot id: H8MXJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1144275:COCOR RS10240
gene id: 1144275:COCOR_RS10240
uniprot id: H8MHQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

1144275:COCOR RS13770
gene id: 1144275:COCOR_RS13770
uniprot id: H8MVJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1144275:COCOR RS13085
gene id: 1144275:COCOR_RS13085
uniprot id: H8MSF4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1144275:COCOR RS05660
gene id: 1144275:COCOR_RS05660
uniprot id: H8MP97
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1144275:COCOR RS19825
gene id: 1144275:COCOR_RS19825
uniprot id: H8MU51
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1144275:COCOR RS26240
gene id: 1144275:COCOR_RS26240
uniprot id: H8MUD0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1144275:COCOR RS10555
gene id: 1144275:COCOR_RS10555
uniprot id: H8MJ18
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS14925
gene id: 1144275:COCOR_RS14925
uniprot id: H8N0B2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1144275:COCOR RS02705
gene id: 1144275:COCOR_RS02705
uniprot id: H8MEL1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1144275:COCOR RS14340
gene id: 1144275:COCOR_RS14340
uniprot id: H8MYL6
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1144275:COCOR RS17435
gene id: 1144275:COCOR_RS17435
uniprot id: H8MKM1
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS26325
gene id: 1144275:COCOR_RS26325
uniprot id: H8MUE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lipase chaperone family.
messages: Cell inner membrane
messages: May be involved in the folding of the extracellular lipase during its passage through the periplasm.

1144275:COCOR RS13130
gene id: 1144275:COCOR_RS13130
uniprot id: H8MTU0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1144275:COCOR RS32820
gene id: 1144275:COCOR_RS32820
uniprot id: H8MUP5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1144275:COCOR RS38345
gene id: 1144275:COCOR_RS38345
uniprot id: H8MRU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1144275:COCOR RS13730
gene id: 1144275:COCOR_RS13730
uniprot id: H8MVI7
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1144275:COCOR RS26530
gene id: 1144275:COCOR_RS26530
uniprot id: H8MVW9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1144275:COCOR RS30510
gene id: 1144275:COCOR_RS30510
uniprot id: H8MMC2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1144275:COCOR RS06750
gene id: 1144275:COCOR_RS06750
uniprot id: H8MTM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

1144275:COCOR RS02130
gene id: 1144275:COCOR_RS02130
uniprot id: H8MZX2
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

1144275:COCOR RS12655
gene id: 1144275:COCOR_RS12655
uniprot id: H8MQY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1144275:COCOR RS09305
gene id: 1144275:COCOR_RS09305
uniprot id: H8MEX6
names: Similarity
messages: Belongs to the BshC family.

1144275:COCOR RS44265
gene id: 1144275:COCOR_RS44265
uniprot id: H8MY91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1144275:COCOR RS32675
gene id: 1144275:COCOR_RS32675
uniprot id: H8MUL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

1144275:COCOR RS22745
gene id: 1144275:COCOR_RS22745
uniprot id: H8MGS6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144275:COCOR RS08785
gene id: 1144275:COCOR_RS08785
uniprot id: H8N1F3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144275:COCOR RS24040
gene id: 1144275:COCOR_RS24040
uniprot id: H8MM35
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1144275:COCOR RS38790
gene id: 1144275:COCOR_RS38790
uniprot id: H8MTB9
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1144275:COCOR RS33640
gene id: 1144275:COCOR_RS33640
uniprot id: H8MXW7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1144275:COCOR RS11345
gene id: 1144275:COCOR_RS11345
uniprot id: H8MLT0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144275:COCOR RS09875
gene id: 1144275:COCOR_RS09875
uniprot id: H8MHI9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1144275:COCOR RS36385
gene id: 1144275:COCOR_RS36385
uniprot id: H8MK03
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1144275:COCOR RS33395
gene id: 1144275:COCOR_RS33395
uniprot id: H8MXR8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS21005
gene id: 1144275:COCOR_RS21005
uniprot id: H8MYX3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1144275:COCOR RS21775
gene id: 1144275:COCOR_RS21775
uniprot id: H8N1X0
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS23690
gene id: 1144275:COCOR_RS23690
uniprot id: H8MKR4
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS16655
gene id: 1144275:COCOR_RS16655
uniprot id: H8MHX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1144275:COCOR RS34010
gene id: 1144275:COCOR_RS34010
uniprot id: H8MZH4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1144275:COCOR RS18660
gene id: 1144275:COCOR_RS18660
uniprot id: H8MPR5
names: Similarity
messages: Belongs to the ClpX chaperone family.

1144275:COCOR RS35090
gene id: 1144275:COCOR_RS35090
uniprot id: H8MFU8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1144275:COCOR RS07670
gene id: 1144275:COCOR_RS07670
uniprot id: H8MWV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1144275:COCOR RS22180
gene id: 1144275:COCOR_RS22180
uniprot id: H8MFC0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1144275:COCOR RS21770
gene id: 1144275:COCOR_RS21770
uniprot id: H8N1W9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1144275:COCOR RS26650
gene id: 1144275:COCOR_RS26650
uniprot id: H8MVZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1144275:COCOR RS05930
gene id: 1144275:COCOR_RS05930
uniprot id: H8MQJ9
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

1144275:COCOR RS24240
gene id: 1144275:COCOR_RS24240
uniprot id: H8MM73
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS23175
gene id: 1144275:COCOR_RS23175
uniprot id: H8MI59
names: Similarity
messages: Belongs to the allantoicase family.

1144275:COCOR RS27840
gene id: 1144275:COCOR_RS27840
uniprot id: H8N0S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

1144275:COCOR RS01265
gene id: 1144275:COCOR_RS01265
uniprot id: H8MWN9
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

1144275:COCOR RS05255
gene id: 1144275:COCOR_RS05255
uniprot id: H8MMW6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

1144275:COCOR RS39550
gene id: 1144275:COCOR_RS39550
uniprot id: H8MWH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

1144275:COCOR RS35385
gene id: 1144275:COCOR_RS35385
uniprot id: H8MH55
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1144275:COCOR RS10165
gene id: 1144275:COCOR_RS10165
uniprot id: H8MHP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1144275:COCOR RS11035
gene id: 1144275:COCOR_RS11035
uniprot id: H8MKG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

1144275:COCOR RS09860
gene id: 1144275:COCOR_RS09860
uniprot id: H8MHI6
names: Similarity
messages: Belongs to the UPF0758 family.

1144275:COCOR RS27200
gene id: 1144275:COCOR_RS27200
uniprot id: H8MXM7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1144275:COCOR RS20885
gene id: 1144275:COCOR_RS20885
uniprot id: H8MYU9
names: Function
names: Similarity
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.

1144275:COCOR RS28545
gene id: 1144275:COCOR_RS28545
uniprot id: H8MFJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

1144275:COCOR RS11070
gene id: 1144275:COCOR_RS11070
uniprot id: H8MLM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1144275:COCOR RS31800
gene id: 1144275:COCOR_RS31800
uniprot id: H8MRI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

1144275:COCOR RS19540
gene id: 1144275:COCOR_RS19540
uniprot id: H8MSM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1144275:COCOR RS38815
gene id: 1144275:COCOR_RS38815
uniprot id: H8MTC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1144275:COCOR RS35120
gene id: 1144275:COCOR_RS35120
uniprot id: H8MFV4
names: Similarity
messages: Belongs to the malate synthase family.

1144275:COCOR RS09870
gene id: 1144275:COCOR_RS09870
uniprot id: H8MHI8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1144275:COCOR RS34955
gene id: 1144275:COCOR_RS34955
uniprot id: H8MFS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.

1144275:COCOR RS07215
gene id: 1144275:COCOR_RS07215
uniprot id: H8MV94
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS06745
gene id: 1144275:COCOR_RS06745
uniprot id: H8MTM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1144275:COCOR RS39530
gene id: 1144275:COCOR_RS39530
uniprot id: H8MWH1
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

1144275:COCOR RS13065
gene id: 1144275:COCOR_RS13065
uniprot id: H8MSF0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1144275:COCOR RS25215
gene id: 1144275:COCOR_RS25215
uniprot id: H8MQ18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

1144275:COCOR RS01235
gene id: 1144275:COCOR_RS01235
uniprot id: H8MWN3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1144275:COCOR RS23605
gene id: 1144275:COCOR_RS23605
uniprot id: H8MJJ7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1144275:COCOR RS12570
gene id: 1144275:COCOR_RS12570
uniprot id: H8MQX0
names: Similarity
messages: Belongs to the CapA family.

1144275:COCOR RS32900
gene id: 1144275:COCOR_RS32900
uniprot id: H8MW41
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1144275:COCOR RS11970
gene id: 1144275:COCOR_RS11970
uniprot id: H8MPF5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

1144275:COCOR RS30800
gene id: 1144275:COCOR_RS30800
uniprot id: H8MMI0
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS08875
gene id: 1144275:COCOR_RS08875
uniprot id: H8N1H1
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

1144275:COCOR RS19500
gene id: 1144275:COCOR_RS19500
uniprot id: H8MSL4
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

1144275:COCOR RS24205
gene id: 1144275:COCOR_RS24205
uniprot id: H8MM66
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1144275:COCOR RS33255
gene id: 1144275:COCOR_RS33255
uniprot id: H8MXN9
names: Similarity
messages: Belongs to the peptidase S45 family.

1144275:COCOR RS23105
gene id: 1144275:COCOR_RS23105
uniprot id: H8MI45
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

1144275:COCOR RS26535
gene id: 1144275:COCOR_RS26535
uniprot id: H8MVX0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1144275:COCOR RS30480
gene id: 1144275:COCOR_RS30480
uniprot id: H8MMB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1144275:COCOR RS25735
gene id: 1144275:COCOR_RS25735
uniprot id: H8MSQ7
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS26875
gene id: 1144275:COCOR_RS26875
uniprot id: H8MXG3
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS32190
gene id: 1144275:COCOR_RS32190
uniprot id: H8MSZ5
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1144275:COCOR RS31430
gene id: 1144275:COCOR_RS31430
uniprot id: H8MQ57
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS40380
gene id: 1144275:COCOR_RS40380
uniprot id: H8MZQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S49 family.
messages: Cell inner membrane

1144275:COCOR RS16665
gene id: 1144275:COCOR_RS16665
uniprot id: H8MHX3
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS42660
gene id: 1144275:COCOR_RS42660
uniprot id: H8MPA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

1144275:COCOR RS05755
gene id: 1144275:COCOR_RS05755
uniprot id: H8MPB7
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

1144275:COCOR RS20030
gene id: 1144275:COCOR_RS20030
uniprot id: H8MVM3
names: Similarity
messages: Belongs to the prespore-cell-inducing factor family.

1144275:COCOR RS31645
gene id: 1144275:COCOR_RS31645
uniprot id: H8MQA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1144275:COCOR RS05125
gene id: 1144275:COCOR_RS05125
uniprot id: H8MMU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1144275:COCOR RS31890
gene id: 1144275:COCOR_RS31890
uniprot id: H8MRK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1144275:COCOR RS35640
gene id: 1144275:COCOR_RS35640
uniprot id: H8MIF0
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

1144275:COCOR RS35580
gene id: 1144275:COCOR_RS35580
uniprot id: H8MH93
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS08045
gene id: 1144275:COCOR_RS08045
uniprot id: H8MYG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1144275:COCOR RS26310
gene id: 1144275:COCOR_RS26310
uniprot id: H8MUE4
names: Similarity
messages: Belongs to the asparagine synthetase family.

1144275:COCOR RS25550
gene id: 1144275:COCOR_RS25550
uniprot id: H8MRD8
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1144275:COCOR RS18920
gene id: 1144275:COCOR_RS18920
uniprot id: H8MR13
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1144275:COCOR RS22545
gene id: 1144275:COCOR_RS22545
uniprot id: H8MGN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell inner membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1144275:COCOR RS39420
gene id: 1144275:COCOR_RS39420
uniprot id: H8MWF0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144275:COCOR RS32315
gene id: 1144275:COCOR_RS32315
uniprot id: H8MT20
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1144275:COCOR RS19390
gene id: 1144275:COCOR_RS19390
uniprot id: H8MSJ2
names: Similarity
messages: Belongs to the DEAD box helicase family.

1144275:COCOR RS05680
gene id: 1144275:COCOR_RS05680
uniprot id: H8MPA2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS33030
gene id: 1144275:COCOR_RS33030
uniprot id: H8MW67
names: Similarity
messages: Belongs to the SCO1/2 family.

1144275:COCOR RS27255
gene id: 1144275:COCOR_RS27255
uniprot id: H8MZ20
names: Similarity
messages: Belongs to the HesB/IscA family.

1144275:COCOR RS38060
gene id: 1144275:COCOR_RS38060
uniprot id: H8MRN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1144275:COCOR RS06105
gene id: 1144275:COCOR_RS06105
uniprot id: H8MQN4
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS04505
gene id: 1144275:COCOR_RS04505
uniprot id: H8MK66
names: Similarity
messages: Belongs to the peptidase S1 family.

1144275:COCOR RS16100
gene id: 1144275:COCOR_RS16100
uniprot id: H8MGG1
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1144275:COCOR RS34525
gene id: 1144275:COCOR_RS34525
uniprot id: H8N2B6
names: Similarity
messages: Belongs to the pyruvate kinase family.

1144275:COCOR RS30020
gene id: 1144275:COCOR_RS30020
uniprot id: H8MJS7
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1144275:COCOR RS17980
gene id: 1144275:COCOR_RS17980
uniprot id: H8MM31
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1144275:COCOR RS11945
gene id: 1144275:COCOR_RS11945
uniprot id: H8MPF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1144275:COCOR RS15180
gene id: 1144275:COCOR_RS15180
uniprot id: H8N1M0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1144275:COCOR RS27625
gene id: 1144275:COCOR_RS27625
uniprot id: H8MZ98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1144275:COCOR RS37125
gene id: 1144275:COCOR_RS37125
uniprot id: H8MMQ2
names: Subcellular Location Annotation
messages: Cytoplasm

1144275:COCOR RS33905
gene id: 1144275:COCOR_RS33905
uniprot id: H8MZF2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1144275:COCOR RS16460
gene id: 1144275:COCOR_RS16460
uniprot id: H8MHT2
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1144275:COCOR RS24210
gene id: 1144275:COCOR_RS24210
uniprot id: H8MM67
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1144275:COCOR RS33140
gene id: 1144275:COCOR_RS33140
uniprot id: H8MW89
names: Similarity
messages: Belongs to the peptidase M4 family.

1144275:COCOR RS15070
gene id: 1144275:COCOR_RS15070
uniprot id: H8N0E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

1144275:COCOR RS22170
gene id: 1144275:COCOR_RS22170
uniprot id: H8MFB8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1144275:COCOR RS33260
gene id: 1144275:COCOR_RS33260
uniprot id: H8MXP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1144275:COCOR RS13625
gene id: 1144275:COCOR_RS13625
uniprot id: H8MVG6
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS34090
gene id: 1144275:COCOR_RS34090
uniprot id: H8N0X1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

1144275:COCOR RS27140
gene id: 1144275:COCOR_RS27140
uniprot id: H8MXL5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS25935
gene id: 1144275:COCOR_RS25935
uniprot id: H8MSU7
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1144275:COCOR RS21695
gene id: 1144275:COCOR_RS21695
uniprot id: H8N1V4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1144275:COCOR RS05480
gene id: 1144275:COCOR_RS05480
uniprot id: H8MP61
names: Similarity
messages: Belongs to the peptidase M16 family.

1144275:COCOR RS30470
gene id: 1144275:COCOR_RS30470
uniprot id: H8MMB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1144275:COCOR RS33390
gene id: 1144275:COCOR_RS33390
uniprot id: H8MXR7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1144275:COCOR RS19370
gene id: 1144275:COCOR_RS19370
uniprot id: H8MSI9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1144275:COCOR RS19700
gene id: 1144275:COCOR_RS19700
uniprot id: H8MU26
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1144275:COCOR RS13320
gene id: 1144275:COCOR_RS13320
uniprot id: H8MTX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1144275:COCOR RS00130
gene id: 1144275:COCOR_RS00130
uniprot id: H8MRY9
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1144275:COCOR RS32485
gene id: 1144275:COCOR_RS32485
uniprot id: H8MUH6
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS08955
gene id: 1144275:COCOR_RS08955
uniprot id: H8N1I7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1144275:COCOR RS01020
gene id: 1144275:COCOR_RS01020
uniprot id: H8MWJ1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1144275:COCOR RS28090
gene id: 1144275:COCOR_RS28090
uniprot id: H8N233
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Membrane

1144275:COCOR RS04370
gene id: 1144275:COCOR_RS04370
uniprot id: H8MK39
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1144275:COCOR RS20895
gene id: 1144275:COCOR_RS20895
uniprot id: H8MYV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S49 family.
messages: Cell inner membrane

1144275:COCOR RS09925
gene id: 1144275:COCOR_RS09925
uniprot id: H8MHJ9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS33270
gene id: 1144275:COCOR_RS33270
uniprot id: H8MXP2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1144275:COCOR RS00045
gene id: 1144275:COCOR_RS00045
uniprot id: H8MRX3
names: Similarity
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

1144275:COCOR RS15470
gene id: 1144275:COCOR_RS15470
uniprot id: H8N1S6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1144275:COCOR RS22940
gene id: 1144275:COCOR_RS22940
uniprot id: H8MI13
names: Similarity
messages: Belongs to the GST superfamily.

1144275:COCOR RS06370
gene id: 1144275:COCOR_RS06370
uniprot id: H8MS21
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1144275:COCOR RS06485
gene id: 1144275:COCOR_RS06485
uniprot id: H8MS45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

1144275:COCOR RS31085
gene id: 1144275:COCOR_RS31085
uniprot id: H8MNU0
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1144275:COCOR RS17335
gene id: 1144275:COCOR_RS17335
uniprot id: H8MKK5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

1144275:COCOR RS22820
gene id: 1144275:COCOR_RS22820
uniprot id: H8MGU1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome
messages: Secreted

1144275:COCOR RS08865
gene id: 1144275:COCOR_RS08865
uniprot id: H8N1G9
names: Similarity
messages: Belongs to the terpene cyclase/mutase family.

1144275:COCOR RS29565
gene id: 1144275:COCOR_RS29565
uniprot id: H8MID0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the homogentisate dioxygenase family.
messages: Hexamer; dimer of trimers.
messages: Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS23745
gene id: 1144275:COCOR_RS23745
uniprot id: H8MKS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1144275:COCOR RS37970
gene id: 1144275:COCOR_RS37970
uniprot id: H8MQG9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1144275:COCOR RS35365
gene id: 1144275:COCOR_RS35365
uniprot id: H8MH51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1144275:COCOR RS30445
gene id: 1144275:COCOR_RS30445
uniprot id: H8ML59
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1144275:COCOR RS30100
gene id: 1144275:COCOR_RS30100
uniprot id: H8MKZ4
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1144275:COCOR RS02460
gene id: 1144275:COCOR_RS02460
uniprot id: H8N195
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1144275:COCOR RS08610
gene id: 1144275:COCOR_RS08610
uniprot id: H8N063
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1144275:COCOR RS30160
gene id: 1144275:COCOR_RS30160
uniprot id: H8ML06
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1144275:COCOR RS25055
gene id: 1144275:COCOR_RS25055
uniprot id: H8MPY7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

1144275:COCOR RS00985
gene id: 1144275:COCOR_RS00985
uniprot id: H8MV61
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144275:COCOR RS11075
gene id: 1144275:COCOR_RS11075
uniprot id: H8MLM6
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1144275:COCOR RS27350
gene id: 1144275:COCOR_RS27350
uniprot id: H8MZ41
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS12580
gene id: 1144275:COCOR_RS12580
uniprot id: H8MQX2
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS27630
gene id: 1144275:COCOR_RS27630
uniprot id: H8MZ99
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS09155
gene id: 1144275:COCOR_RS09155
uniprot id: H8MEU5
names: Similarity
messages: Belongs to the Gfa family.

1144275:COCOR RS21225
gene id: 1144275:COCOR_RS21225
uniprot id: H8MZ19
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1144275:COCOR RS25395
gene id: 1144275:COCOR_RS25395
uniprot id: H8MRA6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1144275:COCOR RS26235
gene id: 1144275:COCOR_RS26235
uniprot id: H8MUC9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS02800
gene id: 1144275:COCOR_RS02800
uniprot id: H8MEN0
names: Similarity
messages: Belongs to the peptidase M1 family.

1144275:COCOR RS14500
gene id: 1144275:COCOR_RS14500
uniprot id: H8MYP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1144275:COCOR RS36575
gene id: 1144275:COCOR_RS36575
uniprot id: H8ML92
names: Similarity
messages: Belongs to the peptidase C56 family.

1144275:COCOR RS06305
gene id: 1144275:COCOR_RS06305
uniprot id: H8MS08
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

1144275:COCOR RS05550
gene id: 1144275:COCOR_RS05550
uniprot id: H8MP75
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1144275:COCOR RS04040
gene id: 1144275:COCOR_RS04040
uniprot id: H8MIS0
names: Activity Regulation
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A peripheral cell membrane enzyme that catalyzes the oxidative decarboxylation of pyruvate to form acetate and CO(2). It channels electrons from the cytoplasm to the respiratory chain at the cell membrane via ubiquinone.
messages: Belongs to the TPP enzyme family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Cell inner membrane
messages: Has 4 domains; the Pyr domain which binds the pyrimidine moiety of the thiamine pyrophosphate cofactor, the FAD-binding domain, the PP-binding domain which binds the pyrophosphate portion of thiamine pyrophosphate and the C-terminal membrane binding region. The C-terminus is held closely against the rest of the protein and covers the active site; during activation it unfolds from the rest of the protein and forms an amphipathic helix upon membrane binding, exposing the active site.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The C-terminus inhibits activity; it has to move for the enzyme to be active. Activated by lipid-binding, which occurs via the C-terminus.

1144275:COCOR RS13015
gene id: 1144275:COCOR_RS13015
uniprot id: H8MSE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

1144275:COCOR RS10980
gene id: 1144275:COCOR_RS10980
uniprot id: H8MKF5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS32385
gene id: 1144275:COCOR_RS32385
uniprot id: H8MT34
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS26685
gene id: 1144275:COCOR_RS26685
uniprot id: H8MW00
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

1144275:COCOR RS15595
gene id: 1144275:COCOR_RS15595
uniprot id: H8MF20
names: Similarity
messages: Belongs to the UDP-glycosyltransferase family.

1144275:COCOR RS13135
gene id: 1144275:COCOR_RS13135
uniprot id: H8MTU1
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1144275:COCOR RS18820
gene id: 1144275:COCOR_RS18820
uniprot id: H8MQZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1144275:COCOR RS00890
gene id: 1144275:COCOR_RS00890
uniprot id: H8MV43
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

1144275:COCOR RS32330
gene id: 1144275:COCOR_RS32330
uniprot id: H8MT23
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1144275:COCOR RS31215
gene id: 1144275:COCOR_RS31215
uniprot id: H8MNW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1144275:COCOR RS24960
gene id: 1144275:COCOR_RS24960
uniprot id: H8MPW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1144275:COCOR RS24810
gene id: 1144275:COCOR_RS24810
uniprot id: H8MNP2
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1144275:COCOR RS17660
gene id: 1144275:COCOR_RS17660
uniprot id: H8MLW8
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

1144275:COCOR RS38495
gene id: 1144275:COCOR_RS38495
uniprot id: H8MT62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1144275:COCOR RS03815
gene id: 1144275:COCOR_RS03815
uniprot id: H8MHI1
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

1144275:COCOR RS18960
gene id: 1144275:COCOR_RS18960
uniprot id: H8MR21
names: Similarity
messages: Belongs to the TPP enzyme family.

1144275:COCOR RS13490
gene id: 1144275:COCOR_RS13490
uniprot id: H8MU08
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1144275:COCOR RS05070
gene id: 1144275:COCOR_RS05070
uniprot id: H8MMS9
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1144275:COCOR RS21475
gene id: 1144275:COCOR_RS21475
uniprot id: H8N0K1
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

1144275:COCOR RS39325
gene id: 1144275:COCOR_RS39325
uniprot id: H8MWC9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1144275:COCOR RS21935
gene id: 1144275:COCOR_RS21935
uniprot id: H8N203
names: Similarity
messages: Belongs to the YciI family.

1144275:COCOR RS29505
gene id: 1144275:COCOR_RS29505
uniprot id: H8MIB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1144275:COCOR RS07120
gene id: 1144275:COCOR_RS07120
uniprot id: H8MV75
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144275:COCOR RS19795
gene id: 1144275:COCOR_RS19795
uniprot id: H8MU45
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1144275:COCOR RS21660
gene id: 1144275:COCOR_RS21660
uniprot id: H8N1U7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1144275:COCOR RS24100
gene id: 1144275:COCOR_RS24100
uniprot id: H8MM47
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1144275:COCOR RS33345
gene id: 1144275:COCOR_RS33345
uniprot id: H8MXQ8
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

1144275:COCOR RS16210
gene id: 1144275:COCOR_RS16210
uniprot id: H8MGI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1144275:COCOR RS16530
gene id: 1144275:COCOR_RS16530
uniprot id: H8MHU7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1144275:COCOR RS22430
gene id: 1144275:COCOR_RS22430
uniprot id: H8MGL3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1144275:COCOR RS11985
gene id: 1144275:COCOR_RS11985
uniprot id: H8MPF8
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

1144275:COCOR RS25885
gene id: 1144275:COCOR_RS25885
uniprot id: H8MST7
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

1144275:COCOR RS34895
gene id: 1144275:COCOR_RS34895
uniprot id: H8MFQ8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1144275:COCOR RS12230
gene id: 1144275:COCOR_RS12230
uniprot id: H8MPK6
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1144275:COCOR RS15725
gene id: 1144275:COCOR_RS15725
uniprot id: H8MF46
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144275:COCOR RS38320
gene id: 1144275:COCOR_RS38320
uniprot id: H8MRU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1144275:COCOR RS11260
gene id: 1144275:COCOR_RS11260
uniprot id: H8MLR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

1144275:COCOR RS37570
gene id: 1144275:COCOR_RS37570
uniprot id: H8MP43
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144275:COCOR RS05690
gene id: 1144275:COCOR_RS05690
uniprot id: H8MPA4
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Homotetramer.

1144275:COCOR RS04825
gene id: 1144275:COCOR_RS04825
uniprot id: H8MLI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1144275:COCOR RS04965
gene id: 1144275:COCOR_RS04965
uniprot id: H8MLK9
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS15250
gene id: 1144275:COCOR_RS15250
uniprot id: H8N1N4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1144275:COCOR RS21430
gene id: 1144275:COCOR_RS21430
uniprot id: H8N0J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane

1144275:COCOR RS24680
gene id: 1144275:COCOR_RS24680
uniprot id: H8MNL6
names: Similarity
messages: Belongs to the GSP E family.

1144275:COCOR RS11605
gene id: 1144275:COCOR_RS11605
uniprot id: H8MN29
names: Similarity
messages: Belongs to the threonine synthase family.

1144275:COCOR RS27615
gene id: 1144275:COCOR_RS27615
uniprot id: H8MZ96
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1144275:COCOR RS09935
gene id: 1144275:COCOR_RS09935
uniprot id: H8MHK1
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1144275:COCOR RS28670
gene id: 1144275:COCOR_RS28670
uniprot id: H8MFL5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

1144275:COCOR RS15145
gene id: 1144275:COCOR_RS15145
uniprot id: H8N1L3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1144275:COCOR RS15230
gene id: 1144275:COCOR_RS15230
uniprot id: H8N1N0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1144275:COCOR RS25225
gene id: 1144275:COCOR_RS25225
uniprot id: H8MQ20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1144275:COCOR RS33245
gene id: 1144275:COCOR_RS33245
uniprot id: H8MWB0
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

1144275:COCOR RS21090
gene id: 1144275:COCOR_RS21090
uniprot id: H8MYZ0
names: Similarity
messages: Belongs to the thioesterase family.

1144275:COCOR RS24045
gene id: 1144275:COCOR_RS24045
uniprot id: H8MM36
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1144275:COCOR RS22570
gene id: 1144275:COCOR_RS22570
uniprot id: H8MGP1
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1144275:COCOR RS19880
gene id: 1144275:COCOR_RS19880
uniprot id: H8MU62
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1144275:COCOR RS12565
gene id: 1144275:COCOR_RS12565
uniprot id: H8MQW9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1144275:COCOR RS12130
gene id: 1144275:COCOR_RS12130
uniprot id: H8MPI7
names: Similarity
messages: Belongs to the peptidase M16 family.

1144275:COCOR RS14495
gene id: 1144275:COCOR_RS14495
uniprot id: H8MYP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1144275:COCOR RS02910
gene id: 1144275:COCOR_RS02910
uniprot id: H8MEQ2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1144275:COCOR RS32210
gene id: 1144275:COCOR_RS32210
uniprot id: H8MSZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1144275:COCOR RS22650
gene id: 1144275:COCOR_RS22650
uniprot id: H8MGQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1144275:COCOR RS33050
gene id: 1144275:COCOR_RS33050
uniprot id: H8MW71
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS27620
gene id: 1144275:COCOR_RS27620
uniprot id: H8MZ97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1144275:COCOR RS22190
gene id: 1144275:COCOR_RS22190
uniprot id: H8MFC2
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS34905
gene id: 1144275:COCOR_RS34905
uniprot id: H8MFR1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS02620
gene id: 1144275:COCOR_RS02620
uniprot id: H8N1C5
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS24465
gene id: 1144275:COCOR_RS24465
uniprot id: H8MNH0
names: Similarity
messages: Belongs to the cytochrome P450 family.

1144275:COCOR RS13115
gene id: 1144275:COCOR_RS13115
uniprot id: H8MTT7
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1144275:COCOR RS31200
gene id: 1144275:COCOR_RS31200
uniprot id: H8MNW3
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1144275:COCOR RS11500
gene id: 1144275:COCOR_RS11500
uniprot id: H8MN08
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1144275:COCOR RS37560
gene id: 1144275:COCOR_RS37560
uniprot id: H8MP41
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1144275:COCOR RS28035
gene id: 1144275:COCOR_RS28035
uniprot id: H8N222
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell inner membrane
messages: Membrane

1144275:COCOR RS35720
gene id: 1144275:COCOR_RS35720
uniprot id: H8MIG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1144275:COCOR RS12650
gene id: 1144275:COCOR_RS12650
uniprot id: H8MQY7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1144275:COCOR RS14485
gene id: 1144275:COCOR_RS14485
uniprot id: H8MYP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

1144275:COCOR RS08310
gene id: 1144275:COCOR_RS08310
uniprot id: H8N002
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS15320
gene id: 1144275:COCOR_RS15320
uniprot id: H8N1P7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1144275:COCOR RS10405
gene id: 1144275:COCOR_RS10405
uniprot id: H8MIY9
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1144275:COCOR RS32130
gene id: 1144275:COCOR_RS32130
uniprot id: H8MSY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1144275:COCOR RS12380
gene id: 1144275:COCOR_RS12380
uniprot id: H8MQT4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1144275:COCOR RS13420
gene id: 1144275:COCOR_RS13420
uniprot id: H8MTZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1144275:COCOR RS19125
gene id: 1144275:COCOR_RS19125
uniprot id: H8MR55
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS23470
gene id: 1144275:COCOR_RS23470
uniprot id: H8MJH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1144275:COCOR RS39990
gene id: 1144275:COCOR_RS39990
uniprot id: H8MY42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1144275:COCOR RS13500
gene id: 1144275:COCOR_RS13500
uniprot id: H8MU10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1144275:COCOR RS25100
gene id: 1144275:COCOR_RS25100
uniprot id: H8MPZ5
names: Caution
names: Function
names: Similarity
messages: Belongs to the ornithine cyclodeaminase/mu-crystallin family. Archaeal alanine dehydrogenase subfamily.
messages: Catalyzes the NAD(+)-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS29715
gene id: 1144275:COCOR_RS29715
uniprot id: H8MJL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1144275:COCOR RS30865
gene id: 1144275:COCOR_RS30865
uniprot id: H8MNP5
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS35415
gene id: 1144275:COCOR_RS35415
uniprot id: H8MH61
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1144275:COCOR RS38515
gene id: 1144275:COCOR_RS38515
uniprot id: H8MT66
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS38920
gene id: 1144275:COCOR_RS38920
uniprot id: H8MUR8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1144275:COCOR RS08540
gene id: 1144275:COCOR_RS08540
uniprot id: H8N049
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1144275:COCOR RS33045
gene id: 1144275:COCOR_RS33045
uniprot id: H8MW70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1144275:COCOR RS33685
gene id: 1144275:COCOR_RS33685
uniprot id: H8MZA8
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

1144275:COCOR RS11350
gene id: 1144275:COCOR_RS11350
uniprot id: H8MLT1
names: Similarity
messages: Belongs to the TPP enzyme family.

1144275:COCOR RS15515
gene id: 1144275:COCOR_RS15515
uniprot id: H8N1T5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144275:COCOR RS32320
gene id: 1144275:COCOR_RS32320
uniprot id: H8MT21
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1144275:COCOR RS27585
gene id: 1144275:COCOR_RS27585
uniprot id: H8MZ90
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

1144275:COCOR RS28975
gene id: 1144275:COCOR_RS28975
uniprot id: H8MGX1
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

1144275:COCOR RS33890
gene id: 1144275:COCOR_RS33890
uniprot id: H8MZE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1144275:COCOR RS40440
gene id: 1144275:COCOR_RS40440
uniprot id: H8N144
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

1144275:COCOR RS19695
gene id: 1144275:COCOR_RS19695
uniprot id: H8MU25
names: Similarity
messages: Belongs to the RecA family.

1144275:COCOR RS22445
gene id: 1144275:COCOR_RS22445
uniprot id: H8MGL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

1144275:COCOR RS10640
gene id: 1144275:COCOR_RS10640
uniprot id: H8MJ35
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS27555
gene id: 1144275:COCOR_RS27555
uniprot id: H8MZ84
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS24530
gene id: 1144275:COCOR_RS24530
uniprot id: H8MNI3
names: Subcellular Location Annotation
messages: Cytoplasm

1144275:COCOR RS26915
gene id: 1144275:COCOR_RS26915
uniprot id: H8MXH1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1144275:COCOR RS33595
gene id: 1144275:COCOR_RS33595
uniprot id: H8MXV8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1144275:COCOR RS35110
gene id: 1144275:COCOR_RS35110
uniprot id: H8MFV2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1144275:COCOR RS00245
gene id: 1144275:COCOR_RS00245
uniprot id: H8MTE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1144275:COCOR RS32135
gene id: 1144275:COCOR_RS32135
uniprot id: H8MSY3
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS19760
gene id: 1144275:COCOR_RS19760
uniprot id: H8MU38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

1144275:COCOR RS31905
gene id: 1144275:COCOR_RS31905
uniprot id: H8MRK4
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS15200
gene id: 1144275:COCOR_RS15200
uniprot id: H8N1M4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1144275:COCOR RS35190
gene id: 1144275:COCOR_RS35190
uniprot id: H8MFW8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1144275:COCOR RS26485
gene id: 1144275:COCOR_RS26485
uniprot id: H8MVW0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1144275:COCOR RS36135
gene id: 1144275:COCOR_RS36135
uniprot id: H8MJV3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1144275:COCOR RS11045
gene id: 1144275:COCOR_RS11045
uniprot id: H8MKG8
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1144275:COCOR RS04950
gene id: 1144275:COCOR_RS04950
uniprot id: H8MLK6
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1144275:COCOR RS07935
gene id: 1144275:COCOR_RS07935
uniprot id: H8MYE4
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1144275:COCOR RS06790
gene id: 1144275:COCOR_RS06790
uniprot id: H8MTN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

1144275:COCOR RS21200
gene id: 1144275:COCOR_RS21200
uniprot id: H8MZ14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

1144275:COCOR RS11245
gene id: 1144275:COCOR_RS11245
uniprot id: H8MLR0
names: Subcellular Location Annotation
messages: Cytoplasm

1144275:COCOR RS22465
gene id: 1144275:COCOR_RS22465
uniprot id: H8MGM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1144275:COCOR RS32465
gene id: 1144275:COCOR_RS32465
uniprot id: H8MUH2
names: Similarity
messages: Belongs to the D-alanine--D-alanine ligase family.

1144275:COCOR RS31915
gene id: 1144275:COCOR_RS31915
uniprot id: H8MRK6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1144275:COCOR RS06510
gene id: 1144275:COCOR_RS06510
uniprot id: H8MS50
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1144275:COCOR RS03385
gene id: 1144275:COCOR_RS03385
uniprot id: H8MG45
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS08270
gene id: 1144275:COCOR_RS08270
uniprot id: H8MZZ3
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS09195
gene id: 1144275:COCOR_RS09195
uniprot id: H8MEV3
names: Subunit
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

1144275:COCOR RS39670
gene id: 1144275:COCOR_RS39670
uniprot id: H8MXX6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1144275:COCOR RS21690
gene id: 1144275:COCOR_RS21690
uniprot id: H8N1V3
names: Similarity
messages: Belongs to the GbsR family.

1144275:COCOR RS11015
gene id: 1144275:COCOR_RS11015
uniprot id: H8MKG2
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1144275:COCOR RS12585
gene id: 1144275:COCOR_RS12585
uniprot id: H8MQX3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1144275:COCOR RS38805
gene id: 1144275:COCOR_RS38805
uniprot id: H8MTC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1144275:COCOR RS19635
gene id: 1144275:COCOR_RS19635
uniprot id: H8MU13
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1144275:COCOR RS38585
gene id: 1144275:COCOR_RS38585
uniprot id: H8MT79
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

1144275:COCOR RS15280
gene id: 1144275:COCOR_RS15280
uniprot id: H8N1P0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1144275:COCOR RS13740
gene id: 1144275:COCOR_RS13740
uniprot id: H8MVI9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1144275:COCOR RS31315
gene id: 1144275:COCOR_RS31315
uniprot id: H8MQ34
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1144275:COCOR RS30370
gene id: 1144275:COCOR_RS30370
uniprot id: H8ML45
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS07760
gene id: 1144275:COCOR_RS07760
uniprot id: H8MWX7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1144275:COCOR RS20940
gene id: 1144275:COCOR_RS20940
uniprot id: H8MYW0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1144275:COCOR RS28220
gene id: 1144275:COCOR_RS28220
uniprot id: H8N259
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

1144275:COCOR RS35645
gene id: 1144275:COCOR_RS35645
uniprot id: H8MIF1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1144275:COCOR RS30060
gene id: 1144275:COCOR_RS30060
uniprot id: H8MKY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1144275:COCOR RS37145
gene id: 1144275:COCOR_RS37145
uniprot id: H8MMQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1144275:COCOR RS31415
gene id: 1144275:COCOR_RS31415
uniprot id: H8MQ54
names: Similarity
messages: Belongs to the GSP E family.

1144275:COCOR RS27570
gene id: 1144275:COCOR_RS27570
uniprot id: H8MZ87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1144275:COCOR RS38810
gene id: 1144275:COCOR_RS38810
uniprot id: H8MTC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1144275:COCOR RS13095
gene id: 1144275:COCOR_RS13095
uniprot id: H8MSF6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1144275:COCOR RS26440
gene id: 1144275:COCOR_RS26440
uniprot id: H8MUG9
names: Similarity
messages: Belongs to the heat shock protein 70 family.

1144275:COCOR RS27825
gene id: 1144275:COCOR_RS27825
uniprot id: H8N0S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane

1144275:COCOR RS04115
gene id: 1144275:COCOR_RS04115
uniprot id: H8MIT5
names: Similarity
messages: Belongs to the thioesterase PaaI family.

1144275:COCOR RS27250
gene id: 1144275:COCOR_RS27250
uniprot id: H8MXN7
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1144275:COCOR RS02655
gene id: 1144275:COCOR_RS02655
uniprot id: H8MEK1
names: Similarity
messages: Belongs to the histone deacetylase family.

1144275:COCOR RS25690
gene id: 1144275:COCOR_RS25690
uniprot id: H8MSP8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1144275:COCOR RS15175
gene id: 1144275:COCOR_RS15175
uniprot id: H8MPU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1144275:COCOR RS32545
gene id: 1144275:COCOR_RS32545
uniprot id: H8MUI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

1144275:COCOR RS13380
gene id: 1144275:COCOR_RS13380
uniprot id: H8MTZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1144275:COCOR RS30075
gene id: 1144275:COCOR_RS30075
uniprot id: H8MKY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1144275:COCOR RS05090
gene id: 1144275:COCOR_RS05090
uniprot id: H8MMT3
names: Function
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

1144275:COCOR RS32815
gene id: 1144275:COCOR_RS32815
uniprot id: H8MUP4
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1144275:COCOR RS05650
gene id: 1144275:COCOR_RS05650
uniprot id: H8MP95
names: Similarity
messages: Belongs to the UPF0047 family.

1144275:COCOR RS12725
gene id: 1144275:COCOR_RS12725
uniprot id: H8MS87
names: Subcellular Location Annotation
messages: Membrane

1144275:COCOR RS33930
gene id: 1144275:COCOR_RS33930
uniprot id: H8MZF8
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1144275:COCOR RS32340
gene id: 1144275:COCOR_RS32340
uniprot id: H8MT25
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1144275:COCOR RS19090
gene id: 1144275:COCOR_RS19090
uniprot id: H8MR47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

1144275:COCOR RS10135
gene id: 1144275:COCOR_RS10135
uniprot id: H8MHN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1144275:COCOR RS25180
gene id: 1144275:COCOR_RS25180
uniprot id: H8MQ11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1144275:COCOR RS15520
gene id: 1144275:COCOR_RS15520
uniprot id: H8N1T6
names: Similarity
messages: Belongs to the AHA1 family.

1144275:COCOR RS33280
gene id: 1144275:COCOR_RS33280
uniprot id: H8MXP4
names: Similarity
messages: Belongs to the YciI family.

1144275:COCOR RS38975
gene id: 1144275:COCOR_RS38975
uniprot id: H8MUS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1144275:COCOR RS00120
gene id: 1144275:COCOR_RS00120
uniprot id: H8MRY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane