1143323:M787 RS02435
gene id: 1143323:M787_RS02435
uniprot id: A0A173DZ21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1143323:M787 RS01390
gene id: 1143323:M787_RS01390
uniprot id: A0A173DYH1
names: Similarity
messages: Belongs to the UDPGP type 1 family.

1143323:M787 RS03880
gene id: 1143323:M787_RS03880
uniprot id: A0A173DZT6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1143323:M787 RS03605
gene id: 1143323:M787_RS03605
uniprot id: A0A173DZQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1143323:M787 RS02485
gene id: 1143323:M787_RS02485
uniprot id: A0A173DZ31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1143323:M787 RS04600
gene id: 1143323:M787_RS04600
uniprot id: A0A173E064
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1143323:M787 RS04140
gene id: 1143323:M787_RS04140
uniprot id: A0A173E012
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1143323:M787 RS02330
gene id: 1143323:M787_RS02330
uniprot id: A0A173DYZ8
names: Similarity
messages: Belongs to the thioredoxin family.

1143323:M787 RS04705
gene id: 1143323:M787_RS04705
uniprot id: A0A173E089
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1143323:M787 RS02930
gene id: 1143323:M787_RS02930
uniprot id: A0A173DZC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1143323:M787 RS00935
gene id: 1143323:M787_RS00935
uniprot id: A0A173DY79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1143323:M787 RS00380
gene id: 1143323:M787_RS00380
uniprot id: A0A173DXY8
names: Similarity
messages: Belongs to the SufE family.

1143323:M787 RS03015
gene id: 1143323:M787_RS03015
uniprot id: A0A173DZC4
names: Subcellular Location Annotation
messages: Membrane

1143323:M787 RS00315
gene id: 1143323:M787_RS00315
uniprot id: A0A173DXW4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1143323:M787 RS03510
gene id: 1143323:M787_RS03510
uniprot id: A0A173DZR4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1143323:M787 RS01650
gene id: 1143323:M787_RS01650
uniprot id: A0A173DYP1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1143323:M787 RS03475
gene id: 1143323:M787_RS03475
uniprot id: A0A173DZM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

1143323:M787 RS02310
gene id: 1143323:M787_RS02310
uniprot id: A0A173DZ01
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1143323:M787 RS03065
gene id: 1143323:M787_RS03065
uniprot id: A0A173DZD7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1143323:M787 RS02360
gene id: 1143323:M787_RS02360
uniprot id: A0A173DZ03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1143323:M787 RS01335
gene id: 1143323:M787_RS01335
uniprot id: A0A173DYF4
names: Subcellular Location Annotation
messages: Membrane

1143323:M787 RS00525
gene id: 1143323:M787_RS00525
uniprot id: A0A173DY10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1143323:M787 RS03980
gene id: 1143323:M787_RS03980
uniprot id: A0A173DZX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1143323:M787 RS02405
gene id: 1143323:M787_RS02405
uniprot id: A0A173DZ07
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1143323:M787 RS03805
gene id: 1143323:M787_RS03805
uniprot id: A0A173DZV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1143323:M787 RS03645
gene id: 1143323:M787_RS03645
uniprot id: A0A173DZS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1143323:M787 RS03535
gene id: 1143323:M787_RS03535
uniprot id: A0A173DZL8
names: Similarity
messages: Belongs to the EUO family.

1143323:M787 RS01115
gene id: 1143323:M787_RS01115
uniprot id: A0A173DYF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

1143323:M787 RS02445
gene id: 1143323:M787_RS02445
uniprot id: A0A173DZ44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1143323:M787 RS03560
gene id: 1143323:M787_RS03560
uniprot id: A0A173DZS4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1143323:M787 RS03160
gene id: 1143323:M787_RS03160
uniprot id: A0A173DZE4
names: Similarity
messages: Belongs to the UPF0235 family.

1143323:M787 RS00795
gene id: 1143323:M787_RS00795
uniprot id: A0A173DY47
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1143323:M787 RS01395
gene id: 1143323:M787_RS01395
uniprot id: A0A173DYJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1143323:M787 RS04345
gene id: 1143323:M787_RS04345
uniprot id: A0A173E034
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1143323:M787 RS00685
gene id: 1143323:M787_RS00685
uniprot id: A0A173DY32
names: Subcellular Location Annotation
messages: Membrane

1143323:M787 RS02540
gene id: 1143323:M787_RS02540
uniprot id: A0A173DZ63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1143323:M787 RS01715
gene id: 1143323:M787_RS01715
uniprot id: A0A173DYN6
names: Subcellular Location Annotation
messages: Periplasm

1143323:M787 RS01970
gene id: 1143323:M787_RS01970
uniprot id: A0A173DYV1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

1143323:M787 RS03185
gene id: 1143323:M787_RS03185
uniprot id: A0A173DZH9
names: Similarity
messages: Belongs to the MYG1 family.

1143323:M787 RS01330
gene id: 1143323:M787_RS01330
uniprot id: A0A173DYF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1143323:M787 RS02905
gene id: 1143323:M787_RS02905
uniprot id: A0A173DZA1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1143323:M787 RS02600
gene id: 1143323:M787_RS02600
uniprot id: A0A173DZ51
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1143323:M787 RS00520
gene id: 1143323:M787_RS00520
uniprot id: A0A173DY30
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1143323:M787 RS03615
gene id: 1143323:M787_RS03615
uniprot id: A0A173DZQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1143323:M787 RS02500
gene id: 1143323:M787_RS02500
uniprot id: A0A173DZ50
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1143323:M787 RS01825
gene id: 1143323:M787_RS01825
uniprot id: A0A173DYR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1143323:M787 RS04125
gene id: 1143323:M787_RS04125
uniprot id: A0A173E013
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1143323:M787 RS02520
gene id: 1143323:M787_RS02520
uniprot id: A0A173DZ38
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1143323:M787 RS00615
gene id: 1143323:M787_RS00615
uniprot id: A0A173DY49
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1143323:M787 RS00135
gene id: 1143323:M787_RS00135
uniprot id: A0A173DXT8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1143323:M787 RS01380
gene id: 1143323:M787_RS01380
uniprot id: A0A173DYG6
names: Subcellular Location Annotation
messages: Cytoplasm

1143323:M787 RS02805
gene id: 1143323:M787_RS02805
uniprot id: A0A173DZ84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1143323:M787 RS02145
gene id: 1143323:M787_RS02145
uniprot id: A0A173DYW6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1143323:M787 RS02940
gene id: 1143323:M787_RS02940
uniprot id: A0A173DZD8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1143323:M787 RS04090
gene id: 1143323:M787_RS04090
uniprot id: A0A173DZZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1143323:M787 RS03360
gene id: 1143323:M787_RS03360
uniprot id: A0A173DZN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1143323:M787 RS01645
gene id: 1143323:M787_RS01645
uniprot id: A0A173DYN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1143323:M787 RS00415
gene id: 1143323:M787_RS00415
uniprot id: A0A173DXY5
names: Similarity
messages: Belongs to the DapB family.

1143323:M787 RS00035
gene id: 1143323:M787_RS00035
uniprot id: A0A173DXS5
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1143323:M787 RS00980
gene id: 1143323:M787_RS00980
uniprot id: A0A173DYB2
names: Similarity
messages: Belongs to the asp23 family.

1143323:M787 RS04460
gene id: 1143323:M787_RS04460
uniprot id: A0A173E060
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1143323:M787 RS03730
gene id: 1143323:M787_RS03730
uniprot id: A0A173DZS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP outer membrane protein family.
messages: Cell outer membrane
messages: cell wall

1143323:M787 RS00815
gene id: 1143323:M787_RS00815
uniprot id: A0A173DY70
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: In the C-terminal section; belongs to the LpxB family.

1143323:M787 RS01630
gene id: 1143323:M787_RS01630
uniprot id: A0A173DYL8
names: Similarity
messages: Belongs to the ParA family.

1143323:M787 RS01140
gene id: 1143323:M787_RS01140
uniprot id: A0A173DYD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1143323:M787 RS02480
gene id: 1143323:M787_RS02480
uniprot id: A0A173DZ53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1143323:M787 RS03365
gene id: 1143323:M787_RS03365
uniprot id: A0A173DZL6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1143323:M787 RS02475
gene id: 1143323:M787_RS02475
uniprot id: A0A173DZ30
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1143323:M787 RS03140
gene id: 1143323:M787_RS03140
uniprot id: A0A173DZE6
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1143323:M787 RS01320
gene id: 1143323:M787_RS01320
uniprot id: A0A173DYG1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1143323:M787 RS03305
gene id: 1143323:M787_RS03305
uniprot id: A0A173DZL5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1143323:M787 RS04445
gene id: 1143323:M787_RS04445
uniprot id: A0A173E066
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1143323:M787 RS00470
gene id: 1143323:M787_RS00470
uniprot id: A0A173DY09
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1143323:M787 RS03440
gene id: 1143323:M787_RS03440
uniprot id: A0A173DZK5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1143323:M787 RS01175
gene id: 1143323:M787_RS01175
uniprot id: A0A173DYC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1143323:M787 RS03080
gene id: 1143323:M787_RS03080
uniprot id: A0A173DZD1
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

1143323:M787 RS00930
gene id: 1143323:M787_RS00930
uniprot id: A0A173DYA9
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1143323:M787 RS00265
gene id: 1143323:M787_RS00265
uniprot id: A0A173DXV6
names: Subcellular Location Annotation
messages: Membrane

1143323:M787 RS02855
gene id: 1143323:M787_RS02855
uniprot id: A0A173DZ93
names: Subunit
messages: Part of a disulfide cross-linked outer membrane complex (COMC) composed of the major outer membrane porin (MOMP), the small cysteine-rich protein (OmcA) and the large cysteine-rich periplasmic protein (OmcB).

1143323:M787 RS02365
gene id: 1143323:M787_RS02365
uniprot id: A0A173DZ10
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1143323:M787 RS03145
gene id: 1143323:M787_RS03145
uniprot id: A0A173DZG7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1143323:M787 RS02300
gene id: 1143323:M787_RS02300
uniprot id: A0A173DYY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

1143323:M787 RS04645
gene id: 1143323:M787_RS04645
uniprot id: A0A173E0C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

1143323:M787 RS04465
gene id: 1143323:M787_RS04465
uniprot id: A0A173E073
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1143323:M787 RS02150
gene id: 1143323:M787_RS02150
uniprot id: A0A173DYW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1143323:M787 RS01450
gene id: 1143323:M787_RS01450
uniprot id: A0A173DYK6
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1143323:M787 RS01200
gene id: 1143323:M787_RS01200
uniprot id: A0A173DYE9
names: Similarity
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Homodimer.

1143323:M787 RS03130
gene id: 1143323:M787_RS03130
uniprot id: A0A173DZE1
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1143323:M787 RS03525
gene id: 1143323:M787_RS03525
uniprot id: A0A173DZN0
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1143323:M787 RS02690
gene id: 1143323:M787_RS02690
uniprot id: A0A173DZ64
names: Similarity
messages: Belongs to the RecO family.

1143323:M787 RS04685
gene id: 1143323:M787_RS04685
uniprot id: A0A173E099
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1143323:M787 RS00440
gene id: 1143323:M787_RS00440
uniprot id: A0A173DY14
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1143323:M787 RS00705
gene id: 1143323:M787_RS00705
uniprot id: A0A173DY34
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1143323:M787 RS01860
gene id: 1143323:M787_RS01860
uniprot id: A0A173DYS8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1143323:M787 RS00580
gene id: 1143323:M787_RS00580
uniprot id: A0A173DY16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

1143323:M787 RS00590
gene id: 1143323:M787_RS00590
uniprot id: A0A173DY43
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1143323:M787 RS00500
gene id: 1143323:M787_RS00500
uniprot id: A0A173DY17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pyruvoyl-dependent arginine decarboxylase family.
messages: Cytoplasm
messages: Part of the AaxABC system, catalyzes the decarboxylation of L-arginine. The arginine uptake by the bacterium in the macrophage may be a virulence factor against the host innate immune response.
messages: Trimer of an alpha-beta dimer.

1143323:M787 RS00030
gene id: 1143323:M787_RS00030
uniprot id: A0A173DXR4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1143323:M787 RS02840
gene id: 1143323:M787_RS02840
uniprot id: A0A173DZ82
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1143323:M787 RS01265
gene id: 1143323:M787_RS01265
uniprot id: A0A173DYG3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

1143323:M787 RS04775
gene id: 1143323:M787_RS04775
uniprot id: A0A173E0C7
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.

1143323:M787 RS00900
gene id: 1143323:M787_RS00900
uniprot id: A0A173DYA7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1143323:M787 RS04425
gene id: 1143323:M787_RS04425
uniprot id: A0A173E069
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1143323:M787 RS01465
gene id: 1143323:M787_RS01465
uniprot id: A0A173DYH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1143323:M787 RS00770
gene id: 1143323:M787_RS00770
uniprot id: A0A173DY72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

1143323:M787 RS02155
gene id: 1143323:M787_RS02155
uniprot id: A0A173DYW7
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1143323:M787 RS02100
gene id: 1143323:M787_RS02100
uniprot id: A0A173DYW3
names: Similarity
messages: Belongs to the FliN/MopA/SpaO family.

1143323:M787 RS00250
gene id: 1143323:M787_RS00250
uniprot id: A0A173DXV2
names: Function
names: PTM
names: Similarity
messages: Autophosphorylated on serine and threonine residues.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
messages: Together with the serine/threonine kinase Pkn1, may play a role in the specific interactions with host proteins during intracellular growth.

1143323:M787 RS02255
gene id: 1143323:M787_RS02255
uniprot id: A0A173DYY0
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1143323:M787 RS04385
gene id: 1143323:M787_RS04385
uniprot id: A0A173E076
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

1143323:M787 RS02020
gene id: 1143323:M787_RS02020
uniprot id: A0A173DYV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

1143323:M787 RS01505
gene id: 1143323:M787_RS01505
uniprot id: A0A173DYM1
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1143323:M787 RS03205
gene id: 1143323:M787_RS03205
uniprot id: A0A173DZJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1143323:M787 RS02850
gene id: 1143323:M787_RS02850
uniprot id: A0A173DZ97
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell outer membrane
messages: In elementary bodies (EBs, the infectious stage, which is able to survive outside the host cell) provides the structural integrity of the outer envelope through disulfide cross-links with the large cysteine-rich periplasmic protein and the major outer membrane porin. It has been described in publications as the Sarkosyl-insoluble COMC (Chlamydia outer membrane complex), and serves as the functional equivalent of peptidoglycan.
messages: Membrane
messages: Part of a disulfide cross-linked outer membrane complex (COMC) composed of the major outer membrane porin (MOMP), the small cysteine-rich protein (OmcA) and the large cysteine-rich periplasmic protein (OmcB).

1143323:M787 RS04330
gene id: 1143323:M787_RS04330
uniprot id: A0A173E051
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1143323:M787 RS01635
gene id: 1143323:M787_RS01635
uniprot id: A0A173DYM9
names: Similarity
messages: Belongs to the UPF0137 (pGP6-D) family.

1143323:M787 RS01515
gene id: 1143323:M787_RS01515
uniprot id: A0A173DYI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YscJ lipoprotein family.
messages: Cell outer membrane
messages: Membrane

1143323:M787 RS00895
gene id: 1143323:M787_RS00895
uniprot id: A0A173DY67
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1143323:M787 RS04000
gene id: 1143323:M787_RS04000
uniprot id: A0A173DZY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1143323:M787 RS03740
gene id: 1143323:M787_RS03740
uniprot id: A0A173DZS8
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1143323:M787 RS00425
gene id: 1143323:M787_RS00425
uniprot id: A0A173DXY4
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

1143323:M787 RS01655
gene id: 1143323:M787_RS01655
uniprot id: A0A173DYN8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1143323:M787 RS03170
gene id: 1143323:M787_RS03170
uniprot id: A0A173DZF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
messages: Homodimer.
messages: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.

1143323:M787 RS02860
gene id: 1143323:M787_RS02860
uniprot id: A0A173DZ96
names: Subcellular Location Annotation
messages: Membrane

1143323:M787 RS02390
gene id: 1143323:M787_RS02390
uniprot id: A0A173DZ23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1143323:M787 RS01210
gene id: 1143323:M787_RS01210
uniprot id: A0A173DYD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

1143323:M787 RS04620
gene id: 1143323:M787_RS04620
uniprot id: A0A173E088
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1143323:M787 RS00700
gene id: 1143323:M787_RS00700
uniprot id: A0A173DY64
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1143323:M787 RS00165
gene id: 1143323:M787_RS00165
uniprot id: A0A173DXU9
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1143323:M787 RS02795
gene id: 1143323:M787_RS02795
uniprot id: A0A173DZ83
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1143323:M787 RS01220
gene id: 1143323:M787_RS01220
uniprot id: A0A173DYH3
names: Function
names: Similarity
messages: Belongs to the histone H1/H5 family. HCT subfamily.
messages: Might have a role analogous to that of eukaryotic histone proteins.

1143323:M787 RS03325
gene id: 1143323:M787_RS03325
uniprot id: A0A173DZI4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family. RnhC subfamily.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1143323:M787 RS00915
gene id: 1143323:M787_RS00915
uniprot id: A0A173DY87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1143323:M787 RS00655
gene id: 1143323:M787_RS00655
uniprot id: A0A173DY40
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1143323:M787 RS00880
gene id: 1143323:M787_RS00880
uniprot id: A0A173DY71
names: Function
messages: Endopeptidase that degrades small peptides of less than 7 kDa, such as glucagon and insulin.

1143323:M787 RS00125
gene id: 1143323:M787_RS00125
uniprot id: A0A173DXV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1143323:M787 RS04035
gene id: 1143323:M787_RS04035
uniprot id: A0A173DZX6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1143323:M787 RS04555
gene id: 1143323:M787_RS04555
uniprot id: A0A173E071
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family. BdbC subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some proteins.

1143323:M787 RS00065
gene id: 1143323:M787_RS00065
uniprot id: A0A173DXU5
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1143323:M787 RS03375
gene id: 1143323:M787_RS03375
uniprot id: A0A173DZJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1143323:M787 RS02925
gene id: 1143323:M787_RS02925
uniprot id: A0A173DZB0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1143323:M787 RS00605
gene id: 1143323:M787_RS00605
uniprot id: A0A173DY24
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1143323:M787 RS00340
gene id: 1143323:M787_RS00340
uniprot id: A0A173DXX8
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1143323:M787 RS01325
gene id: 1143323:M787_RS01325
uniprot id: A0A173DYG5
names: Subcellular Location Annotation
messages: Membrane

1143323:M787 RS01475
gene id: 1143323:M787_RS01475
uniprot id: A0A173DYK2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type II sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

1143323:M787 RS03280
gene id: 1143323:M787_RS03280
uniprot id: A0A173DZH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP outer membrane protein family.
messages: Cell outer membrane
messages: cell wall

1143323:M787 RS01510
gene id: 1143323:M787_RS01510
uniprot id: A0A173DYI4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1143323:M787 RS01775
gene id: 1143323:M787_RS01775
uniprot id: A0A173DYQ1
names: Similarity
messages: Belongs to the sigma-54 factor family.

1143323:M787 RS04070
gene id: 1143323:M787_RS04070
uniprot id: A0A173DZZ8
names: Similarity
messages: Belongs to the ribF family.

1143323:M787 RS02180
gene id: 1143323:M787_RS02180
uniprot id: A0A173DYX1
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1143323:M787 RS01735
gene id: 1143323:M787_RS01735
uniprot id: A0A173DYQ7
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

1143323:M787 RS01790
gene id: 1143323:M787_RS01790
uniprot id: A0A173DYS4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1143323:M787 RS00270
gene id: 1143323:M787_RS00270
uniprot id: A0A173DXW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

1143323:M787 RS00755
gene id: 1143323:M787_RS00755
uniprot id: A0A173DY78
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1143323:M787 RS00595
gene id: 1143323:M787_RS00595
uniprot id: A0A173DY45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1143323:M787 RS02990
gene id: 1143323:M787_RS02990
uniprot id: A0A173DZD6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1143323:M787 RS03285
gene id: 1143323:M787_RS03285
uniprot id: A0A173DZH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP outer membrane protein family.
messages: Cell outer membrane
messages: cell wall

1143323:M787 RS01840
gene id: 1143323:M787_RS01840
uniprot id: A0A173DYT5
names: Similarity
messages: In the C-terminal section; belongs to the DHPS family.

1143323:M787 RS01455
gene id: 1143323:M787_RS01455
uniprot id: A0A173DYL3
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1143323:M787 RS00750
gene id: 1143323:M787_RS00750
uniprot id: A0A173DY73
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1143323:M787 RS00175
gene id: 1143323:M787_RS00175
uniprot id: A0A173DXX0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1143323:M787 RS03055
gene id: 1143323:M787_RS03055
uniprot id: A0A173DZF3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1143323:M787 RS02425
gene id: 1143323:M787_RS02425
uniprot id: A0A173DZ20
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1143323:M787 RS00480
gene id: 1143323:M787_RS00480
uniprot id: A0A173DXZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

1143323:M787 RS00805
gene id: 1143323:M787_RS00805
uniprot id: A0A173DY90
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1143323:M787 RS01540
gene id: 1143323:M787_RS01540
uniprot id: A0A173DYJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Membrane

1143323:M787 RS03135
gene id: 1143323:M787_RS03135
uniprot id: A0A173DZH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1143323:M787 RS02885
gene id: 1143323:M787_RS02885
uniprot id: A0A173DZC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1143323:M787 RS04595
gene id: 1143323:M787_RS04595
uniprot id: A0A173E0B2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1143323:M787 RS02530
gene id: 1143323:M787_RS02530
uniprot id: A0A173DZ35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1143323:M787 RS00570
gene id: 1143323:M787_RS00570
uniprot id: A0A173DY12
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1143323:M787 RS04030
gene id: 1143323:M787_RS04030
uniprot id: A0A173DZX9
names: Similarity
messages: Belongs to the UbiD family.

1143323:M787 RS02395
gene id: 1143323:M787_RS02395
uniprot id: A0A173DZ33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1143323:M787 RS00495
gene id: 1143323:M787_RS00495
uniprot id: A0A173DY19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OprB family.
messages: Cell outer membrane
messages: Facilitates L-arginine uptake, as part of the AaxABC system. The arginine uptake by the bacterium in the macrophage may be a virulence factor against the host innate immune response.
messages: Membrane

1143323:M787 RS00330
gene id: 1143323:M787_RS00330
uniprot id: A0A173DXZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1143323:M787 RS03830
gene id: 1143323:M787_RS03830
uniprot id: A0A173DZS5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1143323:M787 RS01205
gene id: 1143323:M787_RS01205
uniprot id: A0A173DYD4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

1143323:M787 RS04100
gene id: 1143323:M787_RS04100
uniprot id: A0A173E004
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1143323:M787 RS00075
gene id: 1143323:M787_RS00075
uniprot id: A0A173DXT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1143323:M787 RS01420
gene id: 1143323:M787_RS01420
uniprot id: A0A173DYJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1143323:M787 RS03800
gene id: 1143323:M787_RS03800
uniprot id: A0A173DZQ9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1143323:M787 RS04415
gene id: 1143323:M787_RS04415
uniprot id: A0A173E063
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1143323:M787 RS02010
gene id: 1143323:M787_RS02010
uniprot id: A0A173DYU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1143323:M787 RS04280
gene id: 1143323:M787_RS04280
uniprot id: A0A173E042
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1143323:M787 RS01845
gene id: 1143323:M787_RS01845
uniprot id: A0A173DYQ9
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1143323:M787 RS00600
gene id: 1143323:M787_RS00600
uniprot id: A0A173DY25
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Cytoplasm
messages: Monomer.

1143323:M787 RS01095
gene id: 1143323:M787_RS01095
uniprot id: A0A173DYD6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1143323:M787 RS03275
gene id: 1143323:M787_RS03275
uniprot id: A0A173DZH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP outer membrane protein family.
messages: Cell outer membrane
messages: cell wall

1143323:M787 RS02555
gene id: 1143323:M787_RS02555
uniprot id: A0A173DZ52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1143323:M787 RS00275
gene id: 1143323:M787_RS00275
uniprot id: A0A173DXY2
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1143323:M787 RS02815
gene id: 1143323:M787_RS02815
uniprot id: A0A173DZA9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1143323:M787 RS02890
gene id: 1143323:M787_RS02890
uniprot id: A0A173DZ90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1143323:M787 RS02325
gene id: 1143323:M787_RS02325
uniprot id: A0A173DZ22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm

1143323:M787 RS02895
gene id: 1143323:M787_RS02895
uniprot id: A0A173DZA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1143323:M787 RS01305
gene id: 1143323:M787_RS01305
uniprot id: A0A173DYE2
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1143323:M787 RS04485
gene id: 1143323:M787_RS04485
uniprot id: A0A173E093
names: Subcellular Location Annotation
messages: Membrane

1143323:M787 RS03970
gene id: 1143323:M787_RS03970
uniprot id: A0A173DZW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1143323:M787 RS01160
gene id: 1143323:M787_RS01160
uniprot id: A0A173DYD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1143323:M787 RS03600
gene id: 1143323:M787_RS03600
uniprot id: A0A173DZN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1143323:M787 RS04115
gene id: 1143323:M787_RS04115
uniprot id: A0A173DZX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1143323:M787 RS01235
gene id: 1143323:M787_RS01235
uniprot id: A0A173DYG0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

1143323:M787 RS02455
gene id: 1143323:M787_RS02455
uniprot id: A0A173DZ17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1143323:M787 RS04285
gene id: 1143323:M787_RS04285
uniprot id: A0A173E025
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1143323:M787 RS00970
gene id: 1143323:M787_RS00970
uniprot id: A0A173DY88
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1143323:M787 RS03480
gene id: 1143323:M787_RS03480
uniprot id: A0A173DZM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1143323:M787 RS02780
gene id: 1143323:M787_RS02780
uniprot id: A0A173DZB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1143323:M787 RS04395
gene id: 1143323:M787_RS04395
uniprot id: A0A173E054
names: Subcellular Location Annotation
messages: Membrane

1143323:M787 RS01595
gene id: 1143323:M787_RS01595
uniprot id: A0A173DYL1
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1143323:M787 RS01145
gene id: 1143323:M787_RS01145
uniprot id: A0A173DYE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1143323:M787 RS02400
gene id: 1143323:M787_RS02400
uniprot id: A0A173DZ28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1143323:M787 RS02580
gene id: 1143323:M787_RS02580
uniprot id: A0A173DZ47
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

1143323:M787 RS00445
gene id: 1143323:M787_RS00445
uniprot id: A0A173DY13
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

1143323:M787 RS01850
gene id: 1143323:M787_RS01850
uniprot id: A0A173DYR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1143323:M787 RS03875
gene id: 1143323:M787_RS03875
uniprot id: A0A173DZV3
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1143323:M787 RS02440
gene id: 1143323:M787_RS02440
uniprot id: A0A173DZ32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1143323:M787 RS00610
gene id: 1143323:M787_RS00610
uniprot id: A0A173DY37
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1143323:M787 RS00910
gene id: 1143323:M787_RS00910
uniprot id: A0A173DY77
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1143323:M787 RS00940
gene id: 1143323:M787_RS00940
uniprot id: A0A173DYA5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1143323:M787 RS00785
gene id: 1143323:M787_RS00785
uniprot id: A0A173DY76
names: Subcellular Location Annotation
messages: Membrane

1143323:M787 RS00680
gene id: 1143323:M787_RS00680
uniprot id: A0A173DY36
names: Subcellular Location Annotation
messages: Membrane

1143323:M787 RS01490
gene id: 1143323:M787_RS01490
uniprot id: A0A173DYI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Membrane

1143323:M787 RS04250
gene id: 1143323:M787_RS04250
uniprot id: A0A173DZZ7
names: Subcellular Location Annotation
messages: Membrane

1143323:M787 RS02430
gene id: 1143323:M787_RS02430
uniprot id: A0A173DZ45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1143323:M787 RS02315
gene id: 1143323:M787_RS02315
uniprot id: A0A173DYZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

1143323:M787 RS04145
gene id: 1143323:M787_RS04145
uniprot id: A0A173DZY3
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

1143323:M787 RS01890
gene id: 1143323:M787_RS01890
uniprot id: A0A173DYU4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1143323:M787 RS01010
gene id: 1143323:M787_RS01010
uniprot id: A0A173DYC6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1143323:M787 RS03385
gene id: 1143323:M787_RS03385
uniprot id: A0A173DZJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1143323:M787 RS00975
gene id: 1143323:M787_RS00975
uniprot id: A0A173DY99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1143323:M787 RS04515
gene id: 1143323:M787_RS04515
uniprot id: A0A173E081
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1143323:M787 RS03430
gene id: 1143323:M787_RS03430
uniprot id: A0A173DZK7
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1143323:M787 RS01185
gene id: 1143323:M787_RS01185
uniprot id: A0A173DYE1
names: Similarity
messages: Belongs to the transketolase family.

1143323:M787 RS00255
gene id: 1143323:M787_RS00255
uniprot id: A0A173DXW6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1143323:M787 RS00800
gene id: 1143323:M787_RS00800
uniprot id: A0A173DY83
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1143323:M787 RS00070
gene id: 1143323:M787_RS00070
uniprot id: A0A173DXU4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

1143323:M787 RS03985
gene id: 1143323:M787_RS03985
uniprot id: A0A173DZV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1143323:M787 RS01065
gene id: 1143323:M787_RS01065
uniprot id: A0A173DYE8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1143323:M787 RS00390
gene id: 1143323:M787_RS00390
uniprot id: A0A173DY05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1143323:M787 RS01765
gene id: 1143323:M787_RS01765
uniprot id: A0A173DYN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1143323:M787 RS00150
gene id: 1143323:M787_RS00150
uniprot id: A0A173DXU2
names: Similarity
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.

1143323:M787 RS01965
gene id: 1143323:M787_RS01965
uniprot id: A0A173DYU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1143323:M787 RS00505
gene id: 1143323:M787_RS00505
uniprot id: A0A173DY08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Catalyzes the exchange of L-arginine for agmatine. The arginine uptake by the bacterium in the macrophage may be a virulence factor against the host innate immune response.
messages: Membrane

1143323:M787 RS03835
gene id: 1143323:M787_RS03835
uniprot id: A0A173DZU6
names: Function
names: Similarity
messages: Belongs to the histone H1/H5 family. HCT subfamily.
messages: Might have a role in establishing the nucleoid structure of elementary bodies.

1143323:M787 RS01225
gene id: 1143323:M787_RS01225
uniprot id: A0A173DYD2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1143323:M787 RS00010
gene id: 1143323:M787_RS00010
uniprot id: A0A173DXR8
names: Similarity
messages: Belongs to the ClpA/ClpB family.

1143323:M787 RS02590
gene id: 1143323:M787_RS02590
uniprot id: A0A173DZ49
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1143323:M787 RS03265
gene id: 1143323:M787_RS03265
uniprot id: A0A173DZH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP outer membrane protein family.
messages: Cell outer membrane
messages: cell wall

1143323:M787 RS04180
gene id: 1143323:M787_RS04180
uniprot id: A0A173E007
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1143323:M787 RS00740
gene id: 1143323:M787_RS00740
uniprot id: A0A173DY51
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1143323:M787 RS03995
gene id: 1143323:M787_RS03995
uniprot id: A0A173DZV9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1143323:M787 RS02140
gene id: 1143323:M787_RS02140
uniprot id: A0A173DYY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1143323:M787 RS04500
gene id: 1143323:M787_RS04500
uniprot id: A0A173E083
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1143323:M787 RS04185
gene id: 1143323:M787_RS04185
uniprot id: A0A173E008
names: Similarity
messages: Belongs to the fabD family.

1143323:M787 RS00345
gene id: 1143323:M787_RS00345
uniprot id: A0A173DXY3
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1143323:M787 RS03855
gene id: 1143323:M787_RS03855
uniprot id: A0A173DZW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1143323:M787 RS00320
gene id: 1143323:M787_RS00320
uniprot id: A0A173DXX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1143323:M787 RS03675
gene id: 1143323:M787_RS03675
uniprot id: A0A173DZP7
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1143323:M787 RS01100
gene id: 1143323:M787_RS01100
uniprot id: A0A173DYB6
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1143323:M787 RS00280
gene id: 1143323:M787_RS00280
uniprot id: A0A173DXZ0
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

1143323:M787 RS04165
gene id: 1143323:M787_RS04165
uniprot id: A0A173DZY4
names: Similarity
messages: Belongs to the Skp family.

1143323:M787 RS03935
gene id: 1143323:M787_RS03935
uniprot id: A0A173DZV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADP/ATP translocase tlc family.
messages: Membrane

1143323:M787 RS03095
gene id: 1143323:M787_RS03095
uniprot id: A0A173DZF7
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

1143323:M787 RS04060
gene id: 1143323:M787_RS04060
uniprot id: A0A173E014
names: Subcellular Location Annotation
messages: Membrane

1143323:M787 RS01700
gene id: 1143323:M787_RS01700
uniprot id: A0A173DYQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1143323:M787 RS01600
gene id: 1143323:M787_RS01600
uniprot id: A0A173DYN1
names: Similarity
messages: Belongs to the LcrH/SycD chaperone family.

1143323:M787 RS01415
gene id: 1143323:M787_RS01415
uniprot id: A0A173DYJ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

1143323:M787 RS03610
gene id: 1143323:M787_RS03610
uniprot id: A0A173DZT1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1143323:M787 RS03660
gene id: 1143323:M787_RS03660
uniprot id: A0A173DZU3
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1143323:M787 RS04750
gene id: 1143323:M787_RS04750
uniprot id: A0A173E092
names: Similarity
messages: Belongs to the UPF0137 (pGP6-D) family.

1143323:M787 RS00715
gene id: 1143323:M787_RS00715
uniprot id: A0A173DY62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

1143323:M787 RS00860
gene id: 1143323:M787_RS00860
uniprot id: A0A173DY68
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1143323:M787 RS00550
gene id: 1143323:M787_RS00550
uniprot id: A0A173DY23
names: Similarity
messages: Belongs to the LcrH/SycD chaperone family.

1143323:M787 RS03300
gene id: 1143323:M787_RS03300
uniprot id: A0A173DZJ4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1143323:M787 RS03715
gene id: 1143323:M787_RS03715
uniprot id: A0A173DZU7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

1143323:M787 RS00045
gene id: 1143323:M787_RS00045
uniprot id: A0A173DXR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1143323:M787 RS04240
gene id: 1143323:M787_RS04240
uniprot id: A0A173E020
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1143323:M787 RS00965
gene id: 1143323:M787_RS00965
uniprot id: A0A173DYB9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1143323:M787 RS02230
gene id: 1143323:M787_RS02230
uniprot id: A0A173DYY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1143323:M787 RS01720
gene id: 1143323:M787_RS01720
uniprot id: A0A173DYP8
names: Similarity
messages: Belongs to the Pal lipoprotein family.

1143323:M787 RS00370
gene id: 1143323:M787_RS00370
uniprot id: A0A173DXX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1143323:M787 RS00140
gene id: 1143323:M787_RS00140
uniprot id: A0A173DXV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1143323:M787 RS01480
gene id: 1143323:M787_RS01480
uniprot id: A0A173DYI7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1143323:M787 RS01440
gene id: 1143323:M787_RS01440
uniprot id: A0A173DYH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1143323:M787 RS01940
gene id: 1143323:M787_RS01940
uniprot id: A0A173DYS5
names: Similarity
messages: Belongs to the MreC family.

1143323:M787 RS04225
gene id: 1143323:M787_RS04225
uniprot id: A0A173E033
names: Subcellular Location Annotation
messages: Membrane

1143323:M787 RS02790
gene id: 1143323:M787_RS02790
uniprot id: A0A173DZ75
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1143323:M787 RS00790
gene id: 1143323:M787_RS00790
uniprot id: A0A173DY59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1143323:M787 RS02185
gene id: 1143323:M787_RS02185
uniprot id: A0A173DYY4
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1143323:M787 RS03115
gene id: 1143323:M787_RS03115
uniprot id: A0A173DZE5
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

1143323:M787 RS04650
gene id: 1143323:M787_RS04650
uniprot id: A0A173E072
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Long' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1143323:M787 RS02415
gene id: 1143323:M787_RS02415
uniprot id: A0A173DZ18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1143323:M787 RS00115
gene id: 1143323:M787_RS00115
uniprot id: A0A173DXU1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

1143323:M787 RS02050
gene id: 1143323:M787_RS02050
uniprot id: A0A173DYV6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1143323:M787 RS04095
gene id: 1143323:M787_RS04095
uniprot id: A0A173DZX2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.

1143323:M787 RS02960
gene id: 1143323:M787_RS02960
uniprot id: A0A173DZB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP outer membrane protein family.
messages: Cell outer membrane
messages: cell wall

1143323:M787 RS01120
gene id: 1143323:M787_RS01120
uniprot id: A0A173DYB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1143323:M787 RS00780
gene id: 1143323:M787_RS00780
uniprot id: A0A173DY52
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1143323:M787 RS00130
gene id: 1143323:M787_RS00130
uniprot id: A0A173DXV1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1143323:M787 RS00145
gene id: 1143323:M787_RS00145
uniprot id: A0A173DXT7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1143323:M787 RS00905
gene id: 1143323:M787_RS00905
uniprot id: A0A173DYB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1143323:M787 RS02665
gene id: 1143323:M787_RS02665
uniprot id: A0A173DZ78
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1143323:M787 RS02110
gene id: 1143323:M787_RS02110
uniprot id: A0A173DYW1
names: Similarity
messages: Belongs to the bacterial secretin family.

1143323:M787 RS03490
gene id: 1143323:M787_RS03490
uniprot id: A0A173DZL3
names: Function
names: Similarity
messages: Belongs to the HMBS family.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

1143323:M787 RS00670
gene id: 1143323:M787_RS00670
uniprot id: A0A173DY31
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1143323:M787 RS01955
gene id: 1143323:M787_RS01955
uniprot id: A0A173DYT4
names: Subcellular Location Annotation
messages: Membrane

1143323:M787 RS01915
gene id: 1143323:M787_RS01915
uniprot id: A0A173DYU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1143323:M787 RS03870
gene id: 1143323:M787_RS03870
uniprot id: A0A173DZX3
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1143323:M787 RS00430
gene id: 1143323:M787_RS00430
uniprot id: A0A173DXY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1143323:M787 RS04080
gene id: 1143323:M787_RS04080
uniprot id: A0A173DZZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1143323:M787 RS00455
gene id: 1143323:M787_RS00455
uniprot id: A0A173DY00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1143323:M787 RS00660
gene id: 1143323:M787_RS00660
uniprot id: A0A173DY50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1143323:M787 RS04505
gene id: 1143323:M787_RS04505
uniprot id: A0A173E061
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1143323:M787 RS03945
gene id: 1143323:M787_RS03945
uniprot id: A0A173DZU8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1143323:M787 RS02750
gene id: 1143323:M787_RS02750
uniprot id: A0A173DZ73
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1143323:M787 RS04325
gene id: 1143323:M787_RS04325
uniprot id: A0A173E045
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1143323:M787 RS01680
gene id: 1143323:M787_RS01680
uniprot id: A0A173DYM7
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

1143323:M787 RS00310
gene id: 1143323:M787_RS00310
uniprot id: A0A173DXW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1143323:M787 RS02835
gene id: 1143323:M787_RS02835
uniprot id: A0A173DZB8
names: Similarity
messages: Belongs to the EUO family.

1143323:M787 RS03705
gene id: 1143323:M787_RS03705
uniprot id: A0A173DZQ4
names: Similarity
messages: Belongs to the exonuclease superfamily. TREX family.

1143323:M787 RS00465
gene id: 1143323:M787_RS00465
uniprot id: A0A173DXZ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1143323:M787 RS02085
gene id: 1143323:M787_RS02085
uniprot id: A0A173DYV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cytoplasm

1143323:M787 RS02955
gene id: 1143323:M787_RS02955
uniprot id: A0A173DZA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP outer membrane protein family.
messages: Cell outer membrane
messages: cell wall

1143323:M787 RS00995
gene id: 1143323:M787_RS00995
uniprot id: A0A173DYB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1143323:M787 RS00855
gene id: 1143323:M787_RS00855
uniprot id: A0A173DY97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1143323:M787 RS04135
gene id: 1143323:M787_RS04135
uniprot id: A0A173E000
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1143323:M787 RS01315
gene id: 1143323:M787_RS01315
uniprot id: A0A173DYH2
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1143323:M787 RS03785
gene id: 1143323:M787_RS03785
uniprot id: A0A173DZT2
names: Subcellular Location Annotation
messages: Membrane

1143323:M787 RS01755
gene id: 1143323:M787_RS01755
uniprot id: A0A173DYR3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1143323:M787 RS02370
gene id: 1143323:M787_RS02370
uniprot id: A0A173DZ04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1143323:M787 RS04220
gene id: 1143323:M787_RS04220
uniprot id: A0A173E026
names: Subcellular Location Annotation
messages: Membrane

1143323:M787 RS03920
gene id: 1143323:M787_RS03920
uniprot id: A0A173DZV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1143323:M787 RS04390
gene id: 1143323:M787_RS04390
uniprot id: A0A173E021
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1143323:M787 RS03020
gene id: 1143323:M787_RS03020
uniprot id: A0A173DZC6
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1143323:M787 RS01030
gene id: 1143323:M787_RS01030
uniprot id: A0A173DYC0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1143323:M787 RS02565
gene id: 1143323:M787_RS02565
uniprot id: A0A173DZ58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADP/ATP translocase tlc family.
messages: Membrane

1143323:M787 RS01015
gene id: 1143323:M787_RS01015
uniprot id: A0A173DYC9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1143323:M787 RS00220
gene id: 1143323:M787_RS00220
uniprot id: A0A173DXV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

1143323:M787 RS02385
gene id: 1143323:M787_RS02385
uniprot id: A0A173DZ11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1143323:M787 RS00325
gene id: 1143323:M787_RS00325
uniprot id: A0A173DXZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1143323:M787 RS01230
gene id: 1143323:M787_RS01230
uniprot id: A0A173DYD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

1143323:M787 RS04605
gene id: 1143323:M787_RS04605
uniprot id: A0A173E095
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1143323:M787 RS01535
gene id: 1143323:M787_RS01535
uniprot id: A0A173DYK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Membrane

1143323:M787 RS01975
gene id: 1143323:M787_RS01975
uniprot id: A0A173DYS7
names: Subcellular Location Annotation
messages: Membrane

1143323:M787 RS00675
gene id: 1143323:M787_RS00675
uniprot id: A0A173DY57
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1143323:M787 RS02545
gene id: 1143323:M787_RS02545
uniprot id: A0A173DZ41
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1143323:M787 RS03390
gene id: 1143323:M787_RS03390
uniprot id: A0A173DZJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

1143323:M787 RS04410
gene id: 1143323:M787_RS04410
uniprot id: A0A173E048
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1143323:M787 RS03105
gene id: 1143323:M787_RS03105
uniprot id: A0A173DZG5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1143323:M787 RS01745
gene id: 1143323:M787_RS01745
uniprot id: A0A173DYP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1143323:M787 RS03460
gene id: 1143323:M787_RS03460
uniprot id: A0A173DZQ7
names: Subcellular Location Annotation
messages: Membrane

1143323:M787 RS00285
gene id: 1143323:M787_RS00285
uniprot id: A0A173DXY0
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

1143323:M787 RS01350
gene id: 1143323:M787_RS01350
uniprot id: A0A173DYF9
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1143323:M787 RS01570
gene id: 1143323:M787_RS01570
uniprot id: A0A173DYL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1143323:M787 RS03235
gene id: 1143323:M787_RS03235
uniprot id: A0A173DZI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1143323:M787 RS03485
gene id: 1143323:M787_RS03485
uniprot id: A0A173DZL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1143323:M787 RS00405
gene id: 1143323:M787_RS00405
uniprot id: A0A173DXY6
names: Similarity
messages: Belongs to the aspartokinase family.

1143323:M787 RS00850
gene id: 1143323:M787_RS00850
uniprot id: A0A173DY93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP outer membrane protein family.
messages: Cell outer membrane
messages: cell wall

1143323:M787 RS00920
gene id: 1143323:M787_RS00920
uniprot id: A0A173DY98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1143323:M787 RS01400
gene id: 1143323:M787_RS01400
uniprot id: A0A173DYK4
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

1143323:M787 RS01625
gene id: 1143323:M787_RS01625
uniprot id: A0A173DYM6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1143323:M787 RS03790
gene id: 1143323:M787_RS03790
uniprot id: A0A173DZR9
names: Subcellular Location Annotation
messages: Membrane

1143323:M787 RS00110
gene id: 1143323:M787_RS00110
uniprot id: A0A173DXT2
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

1143323:M787 RS00080
gene id: 1143323:M787_RS00080
uniprot id: A0A173DXT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1143323:M787 RS04450
gene id: 1143323:M787_RS04450
uniprot id: A0A173E074
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1143323:M787 RS00215
gene id: 1143323:M787_RS00215
uniprot id: A0A173DXU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1143323:M787 RS02745
gene id: 1143323:M787_RS02745
uniprot id: A0A173DZ80
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1143323:M787 RS02980
gene id: 1143323:M787_RS02980
uniprot id: A0A173DZE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1143323:M787 RS02495
gene id: 1143323:M787_RS02495
uniprot id: A0A173DZ59
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1143323:M787 RS03420
gene id: 1143323:M787_RS03420
uniprot id: A0A173DZJ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

1143323:M787 RS01705
gene id: 1143323:M787_RS01705
uniprot id: A0A173DYQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1143323:M787 RS02880
gene id: 1143323:M787_RS02880
uniprot id: A0A173DZD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1143323:M787 RS02460
gene id: 1143323:M787_RS02460
uniprot id: A0A173DZ26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1143323:M787 RS01960
gene id: 1143323:M787_RS01960
uniprot id: A0A173DYU5
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1143323:M787 RS02920
gene id: 1143323:M787_RS02920
uniprot id: A0A173DZD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1143323:M787 RS02025
gene id: 1143323:M787_RS02025
uniprot id: A0A173DYW0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1143323:M787 RS04510
gene id: 1143323:M787_RS04510
uniprot id: A0A173E067
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1143323:M787 RS01355
gene id: 1143323:M787_RS01355
uniprot id: A0A173DYF2
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1143323:M787 RS02210
gene id: 1143323:M787_RS02210
uniprot id: A0A173DYX9
names: Similarity
messages: Belongs to the ParB family.

1143323:M787 RS03685
gene id: 1143323:M787_RS03685
uniprot id: A0A173DZP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1143323:M787 RS02165
gene id: 1143323:M787_RS02165
uniprot id: A0A173DYW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chlamydial porin (CP) (TC 1.B.2) family.
messages: Cell outer membrane
messages: In elementary bodies (EBs, the infectious stage, which is able to survive outside the host cell) provides the structural integrity of the outer envelope through disulfide cross-links with the small cysteine-rich protein and the large cysteine-rich periplasmic protein. It has been described in publications as the Sarkosyl-insoluble COMC (Chlamydia outer membrane complex), and serves as the functional equivalent of peptidoglycan.
messages: Membrane
messages: Part of a disulfide cross-linked outer membrane complex (COMC) composed of the major outer membrane porin (MOMP), the small cysteine-rich protein (OmcA) and the large cysteine-rich periplasmic protein (OmcB).
messages: Permits diffusion of specific solutes through the outer membrane.

1143323:M787 RS02345
gene id: 1143323:M787_RS02345
uniprot id: A0A173DZ24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1143323:M787 RS01835
gene id: 1143323:M787_RS01835
uniprot id: A0A173DYR5
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

1143323:M787 RS02355
gene id: 1143323:M787_RS02355
uniprot id: A0A173DYZ9
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1143323:M787 RS01770
gene id: 1143323:M787_RS01770
uniprot id: A0A173DYP9
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1143323:M787 RS00530
gene id: 1143323:M787_RS00530
uniprot id: A0A173DY06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1143323:M787 RS03415
gene id: 1143323:M787_RS03415
uniprot id: A0A173DZM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1143323:M787 RS02865
gene id: 1143323:M787_RS02865
uniprot id: A0A173DZB9
names: Similarity
messages: Belongs to the peptidase S41A family.

1143323:M787 RS02645
gene id: 1143323:M787_RS02645
uniprot id: A0A173DZ81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1143323:M787 RS04160
gene id: 1143323:M787_RS04160
uniprot id: A0A173E035
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1143323:M787 RS03295
gene id: 1143323:M787_RS03295
uniprot id: A0A173DZH4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1143323:M787 RS01525
gene id: 1143323:M787_RS01525
uniprot id: A0A173DYL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SctL stator family.
messages: Cytoplasm

1143323:M787 RS01310
gene id: 1143323:M787_RS01310
uniprot id: A0A173DYG7
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1143323:M787 RS02975
gene id: 1143323:M787_RS02975
uniprot id: A0A173DZB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1143323:M787 RS04105
gene id: 1143323:M787_RS04105
uniprot id: A0A173DZX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1143323:M787 RS00645
gene id: 1143323:M787_RS00645
uniprot id: A0A173DY54
names: Subcellular Location Annotation
messages: Membrane

1143323:M787 RS02120
gene id: 1143323:M787_RS02120
uniprot id: A0A173DYX3
names: Caution
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1143323:M787 RS04730
gene id: 1143323:M787_RS04730
uniprot id: A0A173E0A3
names: Similarity
messages: Belongs to the UPF0162 family.

1143323:M787 RS04275
gene id: 1143323:M787_RS04275
uniprot id: A0A173E036
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1143323:M787 RS00745
gene id: 1143323:M787_RS00745
uniprot id: A0A173DY41
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1143323:M787 RS02320
gene id: 1143323:M787_RS02320
uniprot id: A0A173DYZ7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1143323:M787 RS03250
gene id: 1143323:M787_RS03250
uniprot id: A0A173DZK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

1143323:M787 RS01435
gene id: 1143323:M787_RS01435
uniprot id: A0A173DYI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Cytoplasm

1143323:M787 RS00225
gene id: 1143323:M787_RS00225
uniprot id: A0A173DXX2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

1143323:M787 RS03405
gene id: 1143323:M787_RS03405
uniprot id: A0A173DZL1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1143323:M787 RS01910
gene id: 1143323:M787_RS01910
uniprot id: A0A173DYT8
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

1143323:M787 RS00710
gene id: 1143323:M787_RS00710
uniprot id: A0A173DY44
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1143323:M787 RS03380
gene id: 1143323:M787_RS03380
uniprot id: A0A173DZJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1143323:M787 RS01070
gene id: 1143323:M787_RS01070
uniprot id: A0A173DYA2
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1143323:M787 RS04075
gene id: 1143323:M787_RS04075
uniprot id: A0A173E003
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1143323:M787 RS00775
gene id: 1143323:M787_RS00775
uniprot id: A0A173DY75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1143323:M787 RS03010
gene id: 1143323:M787_RS03010
uniprot id: A0A173DZC7
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1143323:M787 RS04625
gene id: 1143323:M787_RS04625
uniprot id: A0A173E0A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1143323:M787 RS01075
gene id: 1143323:M787_RS01075
uniprot id: A0A173DYA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1143323:M787 RS02585
gene id: 1143323:M787_RS02585
uniprot id: A0A173DZ43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1143323:M787 RS00450
gene id: 1143323:M787_RS00450
uniprot id: A0A173DY11
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1143323:M787 RS02450
gene id: 1143323:M787_RS02450
uniprot id: A0A173DZ37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1143323:M787 RS02225
gene id: 1143323:M787_RS02225
uniprot id: A0A173DZ02
names: Similarity
messages: Belongs to the UPF0111 family.

1143323:M787 RS04195
gene id: 1143323:M787_RS04195
uniprot id: A0A173DZZ0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1143323:M787 RS02470
gene id: 1143323:M787_RS02470
uniprot id: A0A173DZ25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1143323:M787 RS02625
gene id: 1143323:M787_RS02625
uniprot id: A0A173DZ55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1143323:M787 RS00400
gene id: 1143323:M787_RS00400
uniprot id: A0A173DY01
names: Function
names: Similarity
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).

1143323:M787 RS01190
gene id: 1143323:M787_RS01190
uniprot id: A0A173DYF8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1143323:M787 RS03630
gene id: 1143323:M787_RS03630
uniprot id: A0A173DZP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1143323:M787 RS01795
gene id: 1143323:M787_RS01795
uniprot id: A0A173DYP6
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1143323:M787 RS03520
gene id: 1143323:M787_RS03520
uniprot id: A0A173DZM1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1143323:M787 RS01445
gene id: 1143323:M787_RS01445
uniprot id: A0A173DYI1
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1143323:M787 RS04660
gene id: 1143323:M787_RS04660
uniprot id: A0A173E0B6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Long' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

1143323:M787 RS03965
gene id: 1143323:M787_RS03965
uniprot id: A0A173DZV4
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1143323:M787 RS04120
gene id: 1143323:M787_RS04120
uniprot id: A0A173E006
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1143323:M787 RS02490
gene id: 1143323:M787_RS02490
uniprot id: A0A173DZ42
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1143323:M787 RS00180
gene id: 1143323:M787_RS00180
uniprot id: A0A173DXV5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1143323:M787 RS03960
gene id: 1143323:M787_RS03960
uniprot id: A0A173DZZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1143323:M787 RS02650
gene id: 1143323:M787_RS02650
uniprot id: A0A173DZ61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1143323:M787 RS00810
gene id: 1143323:M787_RS00810
uniprot id: A0A173DY56
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1143323:M787 RS04175
gene id: 1143323:M787_RS04175
uniprot id: A0A173E023
names: Caution
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1143323:M787 RS00160
gene id: 1143323:M787_RS00160
uniprot id: A0A173DXU0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1143323:M787 RS00295
gene id: 1143323:M787_RS00295
uniprot id: A0A173DXX3
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1143323:M787 RS03075
gene id: 1143323:M787_RS03075
uniprot id: A0A173DZD4
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1143323:M787 RS01800
gene id: 1143323:M787_RS01800
uniprot id: A0A173DYR4
names: Similarity
messages: Belongs to the YggT family.

1143323:M787 RS03955
gene id: 1143323:M787_RS03955
uniprot id: A0A173DZU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

1143323:M787 RS04190
gene id: 1143323:M787_RS04190
uniprot id: A0A173E022
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1143323:M787 RS03515
gene id: 1143323:M787_RS03515
uniprot id: A0A173DZN9
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1143323:M787 RS02235
gene id: 1143323:M787_RS02235
uniprot id: A0A173DYZ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1143323:M787 RS03495
gene id: 1143323:M787_RS03495
uniprot id: A0A173DZP3
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1143323:M787 RS01055
gene id: 1143323:M787_RS01055
uniprot id: A0A173DYA6
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1143323:M787 RS00360
gene id: 1143323:M787_RS00360
uniprot id: A0A173DXZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1143323:M787 RS03585
gene id: 1143323:M787_RS03585
uniprot id: A0A173DZP6
names: Similarity
messages: Belongs to the GcvH family.

1143323:M787 RS01925
gene id: 1143323:M787_RS01925
uniprot id: A0A173DYS1
names: Similarity
messages: Belongs to the GreA/GreB family.

1143323:M787 RS01000
gene id: 1143323:M787_RS01000
uniprot id: A0A173DYA0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1143323:M787 RS01150
gene id: 1143323:M787_RS01150
uniprot id: A0A173DYC5
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1143323:M787 RS00335
gene id: 1143323:M787_RS00335
uniprot id: A0A173DXY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1143323:M787 RS03930
gene id: 1143323:M787_RS03930
uniprot id: A0A173DZW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1143323:M787 RS02465
gene id: 1143323:M787_RS02465
uniprot id: A0A173DZ29
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1143323:M787 RS01580
gene id: 1143323:M787_RS01580
uniprot id: A0A173DYK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane

1143323:M787 RS03500
gene id: 1143323:M787_RS03500
uniprot id: A0A173DZL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1143323:M787 RS00240
gene id: 1143323:M787_RS00240
uniprot id: A0A173DXW0
names: Similarity
messages: Belongs to the pyruvate kinase family.

1143323:M787 RS04420
gene id: 1143323:M787_RS04420
uniprot id: A0A173E030
names: Similarity
messages: Belongs to the peptidase C40 family.

1143323:M787 RS02420
gene id: 1143323:M787_RS02420
uniprot id: A0A173DZ13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1143323:M787 RS01110
gene id: 1143323:M787_RS01110
uniprot id: A0A173DYF1
names: Similarity
messages: Belongs to the CutA family.

1143323:M787 RS00665
gene id: 1143323:M787_RS00665
uniprot id: A0A173DY60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1143323:M787 RS02375
gene id: 1143323:M787_RS02375
uniprot id: A0A173DZ09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1143323:M787 RS03725
gene id: 1143323:M787_RS03725
uniprot id: A0A173DZQ8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1143323:M787 RS04040
gene id: 1143323:M787_RS04040
uniprot id: A0A173DZY9
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1143323:M787 RS01290
gene id: 1143323:M787_RS01290
uniprot id: A0A173DYI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1143323:M787 RS02605
gene id: 1143323:M787_RS02605
uniprot id: A0A173DZ62
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

1143323:M787 RS04055
gene id: 1143323:M787_RS04055
uniprot id: A0A173DZW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Membrane

1143323:M787 RS03025
gene id: 1143323:M787_RS03025
uniprot id: A0A173DZC1
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1143323:M787 RS03060
gene id: 1143323:M787_RS03060
uniprot id: A0A173DZC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1143323:M787 RS03445
gene id: 1143323:M787_RS03445
uniprot id: A0A173DZM6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1143323:M787 RS00155
gene id: 1143323:M787_RS00155
uniprot id: A0A173DXT9
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1143323:M787 RS00475
gene id: 1143323:M787_RS00475
uniprot id: A0A173DXZ6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

1143323:M787 RS02825
gene id: 1143323:M787_RS02825
uniprot id: A0A173DZA6
names: Subcellular Location Annotation
messages: Membrane

1143323:M787 RS01675
gene id: 1143323:M787_RS01675
uniprot id: A0A173DYN4
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1143323:M787 RS03990
gene id: 1143323:M787_RS03990
uniprot id: A0A173DZY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1143323:M787 RS00725
gene id: 1143323:M787_RS00725
uniprot id: A0A173DY42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1143323:M787 RS01935
gene id: 1143323:M787_RS01935
uniprot id: A0A173DYT1
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1143323:M787 RS02410
gene id: 1143323:M787_RS02410
uniprot id: A0A173DZ16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.