1136941:ACH46 RS06260
gene id: 1136941:ACH46_RS06260
uniprot id: A0A0N9N7M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

1136941:ACH46 RS19580
gene id: 1136941:ACH46_RS19580
uniprot id: A0A0N7FV64
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Involved in the hydrocarbon hydroxylating system, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase.

1136941:ACH46 RS16060
gene id: 1136941:ACH46_RS16060
uniprot id: A0A0N9MRR7
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

1136941:ACH46 RS17725
gene id: 1136941:ACH46_RS17725
uniprot id: A0A0N9MTT8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1136941:ACH46 RS01675
gene id: 1136941:ACH46_RS01675
uniprot id: A0A0N9NL88
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.

1136941:ACH46 RS14245
gene id: 1136941:ACH46_RS14245
uniprot id: A0A0N9NIQ5
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS20020
gene id: 1136941:ACH46_RS20020
uniprot id: A0A0N9NCZ8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1136941:ACH46 RS06950
gene id: 1136941:ACH46_RS06950
uniprot id: A0A0N9NF89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1136941:ACH46 RS06730
gene id: 1136941:ACH46_RS06730
uniprot id: A0A0N9NLL5
names: Similarity
messages: Belongs to the glutamate synthase family.

1136941:ACH46 RS09195
gene id: 1136941:ACH46_RS09195
uniprot id: A0A0N9N1Z9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

1136941:ACH46 RS03885
gene id: 1136941:ACH46_RS03885
uniprot id: A0A0N9N8Z6
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

1136941:ACH46 RS12385
gene id: 1136941:ACH46_RS12385
uniprot id: A0A0N9N356
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1136941:ACH46 RS12800
gene id: 1136941:ACH46_RS12800
uniprot id: A0A0N9N399
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS17370
gene id: 1136941:ACH46_RS17370
uniprot id: A0A0N9NLL2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1136941:ACH46 RS15445
gene id: 1136941:ACH46_RS15445
uniprot id: A0A0N9MSX9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1136941:ACH46 RS16560
gene id: 1136941:ACH46_RS16560
uniprot id: A0A0N9NDN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1136941:ACH46 RS04270
gene id: 1136941:ACH46_RS04270
uniprot id: A0A0N7FUB2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1136941:ACH46 RS08485
gene id: 1136941:ACH46_RS08485
uniprot id: A0A0N9NFT5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1136941:ACH46 RS14530
gene id: 1136941:ACH46_RS14530
uniprot id: A0A0N9N4U5
names: Similarity
messages: Belongs to the YciI family.

1136941:ACH46 RS09650
gene id: 1136941:ACH46_RS09650
uniprot id: A0A0N9NB44
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Belongs to the acyl-CoA oxidase family.

1136941:ACH46 RS20210
gene id: 1136941:ACH46_RS20210
uniprot id: A0A0N9MTE4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1136941:ACH46 RS05005
gene id: 1136941:ACH46_RS05005
uniprot id: A0A0N9N9Q6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1136941:ACH46 RS17375
gene id: 1136941:ACH46_RS17375
uniprot id: A0A0N9MS66
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1136941:ACH46 RS11420
gene id: 1136941:ACH46_RS11420
uniprot id: A0A0N7FVD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1136941:ACH46 RS16340
gene id: 1136941:ACH46_RS16340
uniprot id: A0A0N9NIP6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1136941:ACH46 RS19960
gene id: 1136941:ACH46_RS19960
uniprot id: A0A0N9NCY8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1136941:ACH46 RS08270
gene id: 1136941:ACH46_RS08270
uniprot id: A0A0N7FVB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

1136941:ACH46 RS10270
gene id: 1136941:ACH46_RS10270
uniprot id: A0A0N9N3C2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1136941:ACH46 RS05775
gene id: 1136941:ACH46_RS05775
uniprot id: A0A0N9MN06
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

1136941:ACH46 RS16895
gene id: 1136941:ACH46_RS16895
uniprot id: A0A0N9NIW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1136941:ACH46 RS09090
gene id: 1136941:ACH46_RS09090
uniprot id: A0A0N9N2V9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS04175
gene id: 1136941:ACH46_RS04175
uniprot id: A0A0N9MMB1
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS06580
gene id: 1136941:ACH46_RS06580
uniprot id: A0A0N9NG73
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS15775
gene id: 1136941:ACH46_RS15775
uniprot id: A0A0N9NDB7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

1136941:ACH46 RS02370
gene id: 1136941:ACH46_RS02370
uniprot id: A0A0N9N8I2
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS06035
gene id: 1136941:ACH46_RS06035
uniprot id: A0A0N9NAU6
names: Similarity
messages: Belongs to the FBPase class 2 family.

1136941:ACH46 RS14195
gene id: 1136941:ACH46_RS14195
uniprot id: A0A0N9MR68
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1136941:ACH46 RS18500
gene id: 1136941:ACH46_RS18500
uniprot id: A0A0N9NCC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1136941:ACH46 RS11160
gene id: 1136941:ACH46_RS11160
uniprot id: A0A0N9N3P2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

1136941:ACH46 RS05945
gene id: 1136941:ACH46_RS05945
uniprot id: A0A0N9MPL3
names: Similarity
messages: Belongs to the LOG family.

1136941:ACH46 RS09445
gene id: 1136941:ACH46_RS09445
uniprot id: A0A0N9NCA2
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS10375
gene id: 1136941:ACH46_RS10375
uniprot id: A0A0N9NCM9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1136941:ACH46 RS10055
gene id: 1136941:ACH46_RS10055
uniprot id: A0A0N9NB90
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

1136941:ACH46 RS18745
gene id: 1136941:ACH46_RS18745
uniprot id: A0A0N9NKD3
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1136941:ACH46 RS14110
gene id: 1136941:ACH46_RS14110
uniprot id: A0A0N9NLF2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1136941:ACH46 RS08475
gene id: 1136941:ACH46_RS08475
uniprot id: A0A0N9MP15
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1136941:ACH46 RS16245
gene id: 1136941:ACH46_RS16245
uniprot id: A0A0N9NF41
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1136941:ACH46 RS12705
gene id: 1136941:ACH46_RS12705
uniprot id: A0A0N9MRV5
names: Similarity
messages: Belongs to the asparagine synthetase family.

1136941:ACH46 RS08545
gene id: 1136941:ACH46_RS08545
uniprot id: A0A0N9NAR0
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1136941:ACH46 RS04880
gene id: 1136941:ACH46_RS04880
uniprot id: A0A0N9NEG7
names: Similarity
messages: Belongs to the EfeM/EfeO family.

1136941:ACH46 RS13660
gene id: 1136941:ACH46_RS13660
uniprot id: A0A0N9MS80
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

1136941:ACH46 RS16555
gene id: 1136941:ACH46_RS16555
uniprot id: A0A0N9NFF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1136941:ACH46 RS03690
gene id: 1136941:ACH46_RS03690
uniprot id: A0A0N9N0X6
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

1136941:ACH46 RS09275
gene id: 1136941:ACH46_RS09275
uniprot id: A0A0N9NAZ4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1136941:ACH46 RS07925
gene id: 1136941:ACH46_RS07925
uniprot id: A0A0N9N8H6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1136941:ACH46 RS01135
gene id: 1136941:ACH46_RS01135
uniprot id: A0A0N9N868
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

1136941:ACH46 RS08890
gene id: 1136941:ACH46_RS08890
uniprot id: A0A0N9N8U3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1136941:ACH46 RS13185
gene id: 1136941:ACH46_RS13185
uniprot id: A0A0N9N3E5
names: Similarity
messages: Belongs to the AHA1 family.

1136941:ACH46 RS16275
gene id: 1136941:ACH46_RS16275
uniprot id: A0A0N7FUZ7
names: Similarity
messages: Belongs to the AccD/PCCB family.

1136941:ACH46 RS14775
gene id: 1136941:ACH46_RS14775
uniprot id: A0A0N9NAV1
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS14295
gene id: 1136941:ACH46_RS14295
uniprot id: A0A0N9MR76
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

1136941:ACH46 RS14285
gene id: 1136941:ACH46_RS14285
uniprot id: A0A0N7FUV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

1136941:ACH46 RS09390
gene id: 1136941:ACH46_RS09390
uniprot id: A0A0N9NGZ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS12430
gene id: 1136941:ACH46_RS12430
uniprot id: A0A0N9MRQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

1136941:ACH46 RS02725
gene id: 1136941:ACH46_RS02725
uniprot id: A0A0N9NEE2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1136941:ACH46 RS14025
gene id: 1136941:ACH46_RS14025
uniprot id: A0A0N7FUV2
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1136941:ACH46 RS11130
gene id: 1136941:ACH46_RS11130
uniprot id: A0A0N9NLX2
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

1136941:ACH46 RS18175
gene id: 1136941:ACH46_RS18175
uniprot id: A0A0N9NC94
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS00595
gene id: 1136941:ACH46_RS00595
uniprot id: A0A0N9NDQ8
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

1136941:ACH46 RS08105
gene id: 1136941:ACH46_RS08105
uniprot id: A0A0N9NGH9
names: Similarity
messages: Belongs to the peptidase M1 family.

1136941:ACH46 RS16135
gene id: 1136941:ACH46_RS16135
uniprot id: A0A0N9NIL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1136941:ACH46 RS03490
gene id: 1136941:ACH46_RS03490
uniprot id: A0A0N7FU96
names: Caution
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lacks the conserved His residue that binds heme iron in the nitrobindin family.

1136941:ACH46 RS20690
gene id: 1136941:ACH46_RS20690
uniprot id: A0A0N9MTK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1136941:ACH46 RS17540
gene id: 1136941:ACH46_RS17540
uniprot id: A0A0N9NJY2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1136941:ACH46 RS04180
gene id: 1136941:ACH46_RS04180
uniprot id: A0A0N7FUB0
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1136941:ACH46 RS13670
gene id: 1136941:ACH46_RS13670
uniprot id: A0A0N7FUU5
names: Similarity
messages: Belongs to the Fur family.

1136941:ACH46 RS09085
gene id: 1136941:ACH46_RS09085
uniprot id: A0A0N9MU74
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1136941:ACH46 RS17925
gene id: 1136941:ACH46_RS17925
uniprot id: A0A0N9NG07
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1136941:ACH46 RS03315
gene id: 1136941:ACH46_RS03315
uniprot id: A0A0N9NEM1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1136941:ACH46 RS18920
gene id: 1136941:ACH46_RS18920
uniprot id: A0A0N9NJN5
names: Similarity
messages: Belongs to the ArsC family.

1136941:ACH46 RS18605
gene id: 1136941:ACH46_RS18605
uniprot id: A0A0N9NKB3
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1136941:ACH46 RS11140
gene id: 1136941:ACH46_RS11140
uniprot id: A0A0N9NBL4
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

1136941:ACH46 RS00170
gene id: 1136941:ACH46_RS00170
uniprot id: A0A0N7FV88
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS19055
gene id: 1136941:ACH46_RS19055
uniprot id: A0A0N9N6M3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1136941:ACH46 RS10005
gene id: 1136941:ACH46_RS10005
uniprot id: A0A0N9N378
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1136941:ACH46 RS06155
gene id: 1136941:ACH46_RS06155
uniprot id: A0A0N7FUE9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS10470
gene id: 1136941:ACH46_RS10470
uniprot id: A0A0N9MPX7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

1136941:ACH46 RS08165
gene id: 1136941:ACH46_RS08165
uniprot id: A0A0N9NBT5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1136941:ACH46 RS04470
gene id: 1136941:ACH46_RS04470
uniprot id: A0A0N9MP38
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1136941:ACH46 RS03790
gene id: 1136941:ACH46_RS03790
uniprot id: A0A0N9MNV9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1136941:ACH46 RS10385
gene id: 1136941:ACH46_RS10385
uniprot id: A0A0N9NB73
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1136941:ACH46 RS09830
gene id: 1136941:ACH46_RS09830
uniprot id: A0A0N9NAZ0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

1136941:ACH46 RS17730
gene id: 1136941:ACH46_RS17730
uniprot id: A0A0N9NFY2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1136941:ACH46 RS06745
gene id: 1136941:ACH46_RS06745
uniprot id: A0A0N9NB69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1136941:ACH46 RS04885
gene id: 1136941:ACH46_RS04885
uniprot id: A0A0N9N1G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

1136941:ACH46 RS17860
gene id: 1136941:ACH46_RS17860
uniprot id: A0A0N9MTV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1136941:ACH46 RS17640
gene id: 1136941:ACH46_RS17640
uniprot id: A0A0N9NC07
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1136941:ACH46 RS03900
gene id: 1136941:ACH46_RS03900
uniprot id: A0A0N7FUA4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS08450
gene id: 1136941:ACH46_RS08450
uniprot id: A0A0N9NGM6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1136941:ACH46 RS06385
gene id: 1136941:ACH46_RS06385
uniprot id: A0A0N9NFU7
names: Similarity
messages: Belongs to the citrate synthase family.

1136941:ACH46 RS06605
gene id: 1136941:ACH46_RS06605
uniprot id: A0A0N9N0W5
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

1136941:ACH46 RS14015
gene id: 1136941:ACH46_RS14015
uniprot id: A0A0N9MSC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1136941:ACH46 RS15875
gene id: 1136941:ACH46_RS15875
uniprot id: A0A0N9NBA5
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1136941:ACH46 RS11855
gene id: 1136941:ACH46_RS11855
uniprot id: A0A0N9NHU5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1136941:ACH46 RS02205
gene id: 1136941:ACH46_RS02205
uniprot id: A0A0N7FU70
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

1136941:ACH46 RS16130
gene id: 1136941:ACH46_RS16130
uniprot id: A0A0N9MRS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1136941:ACH46 RS05500
gene id: 1136941:ACH46_RS05500
uniprot id: A0A0N9N1Q2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1136941:ACH46 RS11180
gene id: 1136941:ACH46_RS11180
uniprot id: A0A0N9NBG9
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1136941:ACH46 RS10070
gene id: 1136941:ACH46_RS10070
uniprot id: A0A0N9N390
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1136941:ACH46 RS17875
gene id: 1136941:ACH46_RS17875
uniprot id: A0A0N9NK23
names: Similarity
messages: Belongs to the YoeB family.

1136941:ACH46 RS00775
gene id: 1136941:ACH46_RS00775
uniprot id: A0A0N9MZT2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1136941:ACH46 RS13390
gene id: 1136941:ACH46_RS13390
uniprot id: A0A0N9MS44
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1136941:ACH46 RS00910
gene id: 1136941:ACH46_RS00910
uniprot id: A0A0N9N892
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

1136941:ACH46 RS00190
gene id: 1136941:ACH46_RS00190
uniprot id: A0A0N9NCN8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

1136941:ACH46 RS08255
gene id: 1136941:ACH46_RS08255
uniprot id: A0A0N9MNY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1136941:ACH46 RS08465
gene id: 1136941:ACH46_RS08465
uniprot id: A0A0N9MU49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

1136941:ACH46 RS14660
gene id: 1136941:ACH46_RS14660
uniprot id: A0A0N9MRA5
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

1136941:ACH46 RS08040
gene id: 1136941:ACH46_RS08040
uniprot id: A0A0N9N1H0
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

1136941:ACH46 RS07350
gene id: 1136941:ACH46_RS07350
uniprot id: A0A0N9NA50
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

1136941:ACH46 RS06410
gene id: 1136941:ACH46_RS06410
uniprot id: A0A0N9NF23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1136941:ACH46 RS19065
gene id: 1136941:ACH46_RS19065
uniprot id: A0A0N9NCK9
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS16620
gene id: 1136941:ACH46_RS16620
uniprot id: A0A0N9NFH4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1136941:ACH46 RS03875
gene id: 1136941:ACH46_RS03875
uniprot id: A0A0N9N9Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

1136941:ACH46 RS19665
gene id: 1136941:ACH46_RS19665
uniprot id: A0A0N9N7X9
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1136941:ACH46 RS01725
gene id: 1136941:ACH46_RS01725
uniprot id: A0A0N9N8B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1136941:ACH46 RS12435
gene id: 1136941:ACH46_RS12435
uniprot id: A0A0N9NDI1
names: Similarity
messages: Belongs to the YggT family.

1136941:ACH46 RS14345
gene id: 1136941:ACH46_RS14345
uniprot id: A0A0N9N3T2
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

1136941:ACH46 RS02935
gene id: 1136941:ACH46_RS02935
uniprot id: A0A0N9N923
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1136941:ACH46 RS04535
gene id: 1136941:ACH46_RS04535
uniprot id: A0A0N9MP43
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1136941:ACH46 RS10435
gene id: 1136941:ACH46_RS10435
uniprot id: A0A0N9NCP3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

1136941:ACH46 RS12755
gene id: 1136941:ACH46_RS12755
uniprot id: A0A0N9N476
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1136941:ACH46 RS10405
gene id: 1136941:ACH46_RS10405
uniprot id: A0A0N9MPW7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

1136941:ACH46 RS05570
gene id: 1136941:ACH46_RS05570
uniprot id: A0A0N7FUD7
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1136941:ACH46 RS06725
gene id: 1136941:ACH46_RS06725
uniprot id: A0A0N9N254
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1136941:ACH46 RS13865
gene id: 1136941:ACH46_RS13865
uniprot id: A0A0N9NE35
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS09170
gene id: 1136941:ACH46_RS09170
uniprot id: A0A0N9MQL6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1136941:ACH46 RS11590
gene id: 1136941:ACH46_RS11590
uniprot id: A0A0N9MRF8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1136941:ACH46 RS10015
gene id: 1136941:ACH46_RS10015
uniprot id: A0A0N9NE88
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS13600
gene id: 1136941:ACH46_RS13600
uniprot id: A0A0N9NGK4
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

1136941:ACH46 RS10885
gene id: 1136941:ACH46_RS10885
uniprot id: A0A0N9MSZ3
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS09755
gene id: 1136941:ACH46_RS09755
uniprot id: A0A0N9NCE4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1136941:ACH46 RS16660
gene id: 1136941:ACH46_RS16660
uniprot id: A0A0N9NDM7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1136941:ACH46 RS19930
gene id: 1136941:ACH46_RS19930
uniprot id: A0A0N7FV71
names: Similarity
messages: Belongs to the TPP enzyme family.

1136941:ACH46 RS20685
gene id: 1136941:ACH46_RS20685
uniprot id: A0A0N7FV87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1136941:ACH46 RS03750
gene id: 1136941:ACH46_RS03750
uniprot id: A0A0N9MM77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell.

1136941:ACH46 RS12180
gene id: 1136941:ACH46_RS12180
uniprot id: A0A0N9NH63
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1136941:ACH46 RS05080
gene id: 1136941:ACH46_RS05080
uniprot id: A0A0N9NEJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1136941:ACH46 RS17495
gene id: 1136941:ACH46_RS17495
uniprot id: A0A0N9MS81
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

1136941:ACH46 RS14040
gene id: 1136941:ACH46_RS14040
uniprot id: A0A0N9NIM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1136941:ACH46 RS02775
gene id: 1136941:ACH46_RS02775
uniprot id: A0A0N9NKJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

1136941:ACH46 RS05990
gene id: 1136941:ACH46_RS05990
uniprot id: A0A0N9NA06
names: Similarity
names: Subunit
messages: Belongs to the multicopper oxidase family.
messages: Homotrimer.

1136941:ACH46 RS09765
gene id: 1136941:ACH46_RS09765
uniprot id: A0A0N9NH39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1136941:ACH46 RS15070
gene id: 1136941:ACH46_RS15070
uniprot id: A0A0N9N424
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

1136941:ACH46 RS03120
gene id: 1136941:ACH46_RS03120
uniprot id: A0A0N7FU88
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1136941:ACH46 RS08380
gene id: 1136941:ACH46_RS08380
uniprot id: A0A0N9NAP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1136941:ACH46 RS00800
gene id: 1136941:ACH46_RS00800
uniprot id: A0A0N7FU42
names: Similarity
messages: Belongs to the asparagine synthetase family.

1136941:ACH46 RS05135
gene id: 1136941:ACH46_RS05135
uniprot id: A0A0N9NFF3
names: Similarity
messages: Belongs to the CinA family.

1136941:ACH46 RS05950
gene id: 1136941:ACH46_RS05950
uniprot id: A0A0N9NAT7
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

1136941:ACH46 RS10310
gene id: 1136941:ACH46_RS10310
uniprot id: A0A0N9N2F2
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

1136941:ACH46 RS14600
gene id: 1136941:ACH46_RS14600
uniprot id: A0A0N7FUW3
names: Similarity
messages: Belongs to the UPF0045 family.

1136941:ACH46 RS13935
gene id: 1136941:ACH46_RS13935
uniprot id: A0A0N9MSB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1136941:ACH46 RS06720
gene id: 1136941:ACH46_RS06720
uniprot id: A0A0N9NF57
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

1136941:ACH46 RS05815
gene id: 1136941:ACH46_RS05815
uniprot id: A0A0N9NG44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

1136941:ACH46 RS04695
gene id: 1136941:ACH46_RS04695
uniprot id: A0A0N9N988
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1136941:ACH46 RS03925
gene id: 1136941:ACH46_RS03925
uniprot id: A0A0N9N772
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS17385
gene id: 1136941:ACH46_RS17385
uniprot id: A0A0N9NJ28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1136941:ACH46 RS08790
gene id: 1136941:ACH46_RS08790
uniprot id: A0A0N9NFX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1136941:ACH46 RS13010
gene id: 1136941:ACH46_RS13010
uniprot id: A0A0N9MS01
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1136941:ACH46 RS07170
gene id: 1136941:ACH46_RS07170
uniprot id: A0A0N9MPY8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1136941:ACH46 RS06555
gene id: 1136941:ACH46_RS06555
uniprot id: A0A0N9NF42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.

1136941:ACH46 RS12990
gene id: 1136941:ACH46_RS12990
uniprot id: A0A0N9MQQ0
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

1136941:ACH46 RS01885
gene id: 1136941:ACH46_RS01885
uniprot id: A0A0N9N8D6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS02300
gene id: 1136941:ACH46_RS02300
uniprot id: A0A0N9MNA1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

1136941:ACH46 RS08035
gene id: 1136941:ACH46_RS08035
uniprot id: A0A0N9NGH0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1136941:ACH46 RS12465
gene id: 1136941:ACH46_RS12465
uniprot id: A0A0N9MQJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1136941:ACH46 RS17285
gene id: 1136941:ACH46_RS17285
uniprot id: A0A0N9NJU7
names: Similarity
messages: Belongs to the Nth/MutY family.

1136941:ACH46 RS06990
gene id: 1136941:ACH46_RS06990
uniprot id: A0A0N7FUG5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1136941:ACH46 RS18130
gene id: 1136941:ACH46_RS18130
uniprot id: A0A0N9NED0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

1136941:ACH46 RS02265
gene id: 1136941:ACH46_RS02265
uniprot id: A0A0N9N8V3
names: Similarity
messages: Belongs to the peptidase M1 family.

1136941:ACH46 RS01205
gene id: 1136941:ACH46_RS01205
uniprot id: A0A0N9NDX1
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS02350
gene id: 1136941:ACH46_RS02350
uniprot id: A0A0N9N0G0
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

1136941:ACH46 RS15400
gene id: 1136941:ACH46_RS15400
uniprot id: A0A0N9NJ38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1136941:ACH46 RS10495
gene id: 1136941:ACH46_RS10495
uniprot id: A0A0N9N9E7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1136941:ACH46 RS14100
gene id: 1136941:ACH46_RS14100
uniprot id: A0A0N9NCJ1
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS18415
gene id: 1136941:ACH46_RS18415
uniprot id: A0A0N9NCB8
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

1136941:ACH46 RS14595
gene id: 1136941:ACH46_RS14595
uniprot id: A0A0N9NI10
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1136941:ACH46 RS19050
gene id: 1136941:ACH46_RS19050
uniprot id: A0A0N9NJQ7
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

1136941:ACH46 RS16190
gene id: 1136941:ACH46_RS16190
uniprot id: A0A0N9MW63
names: Subcellular Location Annotation
messages: Secreted

1136941:ACH46 RS06515
gene id: 1136941:ACH46_RS06515
uniprot id: A0A0N9MPS3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS12750
gene id: 1136941:ACH46_RS12750
uniprot id: A0A0N9MVU3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1136941:ACH46 RS11535
gene id: 1136941:ACH46_RS11535
uniprot id: A0A0N9NBR1
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

1136941:ACH46 RS14525
gene id: 1136941:ACH46_RS14525
uniprot id: A0A0N9NI03
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1136941:ACH46 RS09710
gene id: 1136941:ACH46_RS09710
uniprot id: A0A0N9N282
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1136941:ACH46 RS09890
gene id: 1136941:ACH46_RS09890
uniprot id: A0A0N9N968
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1136941:ACH46 RS08375
gene id: 1136941:ACH46_RS08375
uniprot id: A0A0N9N1N3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

1136941:ACH46 RS15795
gene id: 1136941:ACH46_RS15795
uniprot id: A0A0N9ND96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1136941:ACH46 RS14885
gene id: 1136941:ACH46_RS14885
uniprot id: A0A0N9MRB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

1136941:ACH46 RS17210
gene id: 1136941:ACH46_RS17210
uniprot id: A0A0N9NJT8
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

1136941:ACH46 RS13120
gene id: 1136941:ACH46_RS13120
uniprot id: A0A0N9N3D6
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS02170
gene id: 1136941:ACH46_RS02170
uniprot id: A0A0N9NE56
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

1136941:ACH46 RS03910
gene id: 1136941:ACH46_RS03910
uniprot id: A0A0N9MM88
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1136941:ACH46 RS05035
gene id: 1136941:ACH46_RS05035
uniprot id: A0A0N9MP91
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS07825
gene id: 1136941:ACH46_RS07825
uniprot id: A0A0N9NFK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1136941:ACH46 RS09105
gene id: 1136941:ACH46_RS09105
uniprot id: A0A0N9MQK6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1136941:ACH46 RS17890
gene id: 1136941:ACH46_RS17890
uniprot id: A0A0N9NEB0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1136941:ACH46 RS05755
gene id: 1136941:ACH46_RS05755
uniprot id: A0A0N9N0J9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS17755
gene id: 1136941:ACH46_RS17755
uniprot id: A0A0N9NE87
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

1136941:ACH46 RS08065
gene id: 1136941:ACH46_RS08065
uniprot id: A0A0N9N2K8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1136941:ACH46 RS13355
gene id: 1136941:ACH46_RS13355
uniprot id: A0A0N9NHL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

1136941:ACH46 RS04800
gene id: 1136941:ACH46_RS04800
uniprot id: A0A0N9N9N6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1136941:ACH46 RS06500
gene id: 1136941:ACH46_RS06500
uniprot id: A0A0N7FUF6
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

1136941:ACH46 RS00675
gene id: 1136941:ACH46_RS00675
uniprot id: A0A0N9NH60
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS13740
gene id: 1136941:ACH46_RS13740
uniprot id: A0A0N9NCD7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1136941:ACH46 RS10475
gene id: 1136941:ACH46_RS10475
uniprot id: A0A0N9NGI2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

1136941:ACH46 RS13685
gene id: 1136941:ACH46_RS13685
uniprot id: A0A0N9NII8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1136941:ACH46 RS16045
gene id: 1136941:ACH46_RS16045
uniprot id: A0A0N9NJB9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1136941:ACH46 RS10560
gene id: 1136941:ACH46_RS10560
uniprot id: A0A0N9N3F7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS09810
gene id: 1136941:ACH46_RS09810
uniprot id: A0A0N9N350
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1136941:ACH46 RS14690
gene id: 1136941:ACH46_RS14690
uniprot id: A0A0N9MSJ6
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

1136941:ACH46 RS05855
gene id: 1136941:ACH46_RS05855
uniprot id: A0A0N7FUE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1136941:ACH46 RS15315
gene id: 1136941:ACH46_RS15315
uniprot id: A0A0N9MSW1
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS18060
gene id: 1136941:ACH46_RS18060
uniprot id: A0A0N7FV35
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS07130
gene id: 1136941:ACH46_RS07130
uniprot id: A0A0N9NG58
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1136941:ACH46 RS01965
gene id: 1136941:ACH46_RS01965
uniprot id: A0A0N9N928
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1136941:ACH46 RS08390
gene id: 1136941:ACH46_RS08390
uniprot id: A0A0N9MP01
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1136941:ACH46 RS12720
gene id: 1136941:ACH46_RS12720
uniprot id: A0A0N9NI54
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1136941:ACH46 RS15480
gene id: 1136941:ACH46_RS15480
uniprot id: A0A0N9MRK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1136941:ACH46 RS19015
gene id: 1136941:ACH46_RS19015
uniprot id: A0A0N9NGF9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1136941:ACH46 RS04975
gene id: 1136941:ACH46_RS04975
uniprot id: A0A0N9MP83
names: Similarity
messages: Belongs to the pirin family.

1136941:ACH46 RS08565
gene id: 1136941:ACH46_RS08565
uniprot id: A0A0N7FUJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1136941:ACH46 RS02885
gene id: 1136941:ACH46_RS02885
uniprot id: A0A0N9MNI7
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

1136941:ACH46 RS04350
gene id: 1136941:ACH46_RS04350
uniprot id: A0A0N9N040
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1136941:ACH46 RS07780
gene id: 1136941:ACH46_RS07780
uniprot id: A0A0N9MQ45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1136941:ACH46 RS00965
gene id: 1136941:ACH46_RS00965
uniprot id: A0A0N9N8B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

1136941:ACH46 RS11680
gene id: 1136941:ACH46_RS11680
uniprot id: A0A0N9ND91
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1136941:ACH46 RS05230
gene id: 1136941:ACH46_RS05230
uniprot id: A0A0N9NFG3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1136941:ACH46 RS08180
gene id: 1136941:ACH46_RS08180
uniprot id: A0A0N9NGJ0
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1136941:ACH46 RS15485
gene id: 1136941:ACH46_RS15485
uniprot id: A0A0N9NIC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1136941:ACH46 RS06480
gene id: 1136941:ACH46_RS06480
uniprot id: A0A0N9NA59
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

1136941:ACH46 RS07205
gene id: 1136941:ACH46_RS07205
uniprot id: A0A0N9NG66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1136941:ACH46 RS11155
gene id: 1136941:ACH46_RS11155
uniprot id: A0A0N9NGT6
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

1136941:ACH46 RS18680
gene id: 1136941:ACH46_RS18680
uniprot id: A0A0N9N5L7
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1136941:ACH46 RS20510
gene id: 1136941:ACH46_RS20510
uniprot id: A0A0N9NK98
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS03375
gene id: 1136941:ACH46_RS03375
uniprot id: A0A0N9MZS2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Catalyzes the synthesis of activated sulfate.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1136941:ACH46 RS06575
gene id: 1136941:ACH46_RS06575
uniprot id: A0A0N9NB54
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1136941:ACH46 RS11370
gene id: 1136941:ACH46_RS11370
uniprot id: A0A0N9MQ73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1136941:ACH46 RS12850
gene id: 1136941:ACH46_RS12850
uniprot id: A0A0N9NA58
names: Similarity
messages: Belongs to the glutamine synthetase family.

1136941:ACH46 RS09885
gene id: 1136941:ACH46_RS09885
uniprot id: A0A0N9MU98
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS17220
gene id: 1136941:ACH46_RS17220
uniprot id: A0A0N9NDZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1136941:ACH46 RS06820
gene id: 1136941:ACH46_RS06820
uniprot id: A0A0N9N9Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1136941:ACH46 RS01850
gene id: 1136941:ACH46_RS01850
uniprot id: A0A0N9N099
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1136941:ACH46 RS00020
gene id: 1136941:ACH46_RS00020
uniprot id: A0A0N9N774
names: Similarity
messages: Belongs to the UPF0232 family.

1136941:ACH46 RS15825
gene id: 1136941:ACH46_RS15825
uniprot id: A0A0N9MT26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1136941:ACH46 RS00015
gene id: 1136941:ACH46_RS00015
uniprot id: A0A0N9N7Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

1136941:ACH46 RS02060
gene id: 1136941:ACH46_RS02060
uniprot id: A0A0N7FV94
names: Similarity
messages: Belongs to the GSP E family.

1136941:ACH46 RS12290
gene id: 1136941:ACH46_RS12290
uniprot id: A0A0N9MRP2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS05435
gene id: 1136941:ACH46_RS05435
uniprot id: A0A0N9MPC6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
messages: Tetramer of two alpha and two beta subunits.

1136941:ACH46 RS08555
gene id: 1136941:ACH46_RS08555
uniprot id: A0A0N9NFU3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS01280
gene id: 1136941:ACH46_RS01280
uniprot id: A0A0N9NDX6
names: Similarity
messages: Belongs to the universal stress protein A family.

1136941:ACH46 RS17025
gene id: 1136941:ACH46_RS17025
uniprot id: A0A0N9MS33
names: Similarity
messages: Belongs to the ALAD family.

1136941:ACH46 RS06390
gene id: 1136941:ACH46_RS06390
uniprot id: A0A0N9N0S9
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

1136941:ACH46 RS01315
gene id: 1136941:ACH46_RS01315
uniprot id: A0A0N7FU53
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS01560
gene id: 1136941:ACH46_RS01560
uniprot id: A0A0N9MN09
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1136941:ACH46 RS11990
gene id: 1136941:ACH46_RS11990
uniprot id: A0A0N9NBR9
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS14045
gene id: 1136941:ACH46_RS14045
uniprot id: A0A0N9N3P3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1136941:ACH46 RS06875
gene id: 1136941:ACH46_RS06875
uniprot id: A0A0N7FUG3
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1136941:ACH46 RS07750
gene id: 1136941:ACH46_RS07750
uniprot id: A0A0N9NG32
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

1136941:ACH46 RS16475
gene id: 1136941:ACH46_RS16475
uniprot id: A0A0N9NBI7
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1136941:ACH46 RS13805
gene id: 1136941:ACH46_RS13805
uniprot id: A0A0N7FUU8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1136941:ACH46 RS15055
gene id: 1136941:ACH46_RS15055
uniprot id: A0A0N9NEK4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1136941:ACH46 RS01655
gene id: 1136941:ACH46_RS01655
uniprot id: A0A0N9NE11
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS16480
gene id: 1136941:ACH46_RS16480
uniprot id: A0A0N9MTA9
names: Similarity
messages: Belongs to the mycobacterial A85 antigen family.

1136941:ACH46 RS18555
gene id: 1136941:ACH46_RS18555
uniprot id: A0A0N9NEL7
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS15385
gene id: 1136941:ACH46_RS15385
uniprot id: A0A0N9MSW9
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1136941:ACH46 RS04675
gene id: 1136941:ACH46_RS04675
uniprot id: A0A0N9N1D8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1136941:ACH46 RS18625
gene id: 1136941:ACH46_RS18625
uniprot id: A0A0N9MSQ3
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1136941:ACH46 RS20360
gene id: 1136941:ACH46_RS20360
uniprot id: A0A0N9ND50
names: Similarity
messages: Belongs to the CsoR family.

1136941:ACH46 RS17075
gene id: 1136941:ACH46_RS17075
uniprot id: A0A0N9NF08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1136941:ACH46 RS03090
gene id: 1136941:ACH46_RS03090
uniprot id: A0A0N9NDP0
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family.

1136941:ACH46 RS10315
gene id: 1136941:ACH46_RS10315
uniprot id: A0A0N9NBC9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1136941:ACH46 RS07380
gene id: 1136941:ACH46_RS07380
uniprot id: A0A0N7FUH3
names: Similarity
messages: Belongs to the peptidase S58 family.

1136941:ACH46 RS18995
gene id: 1136941:ACH46_RS18995
uniprot id: A0A0N7FV53
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1136941:ACH46 RS18780
gene id: 1136941:ACH46_RS18780
uniprot id: A0A0N9NCG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.

1136941:ACH46 RS16600
gene id: 1136941:ACH46_RS16600
uniprot id: A0A0N9N5M7
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1136941:ACH46 RS16165
gene id: 1136941:ACH46_RS16165
uniprot id: A0A0N7FVE9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1136941:ACH46 RS14155
gene id: 1136941:ACH46_RS14155
uniprot id: A0A0N9MSE4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1136941:ACH46 RS17885
gene id: 1136941:ACH46_RS17885
uniprot id: A0A0N9N5A7
names: Similarity
messages: Belongs to the CobH/CbiC family.

1136941:ACH46 RS18635
gene id: 1136941:ACH46_RS18635
uniprot id: A0A0N9N6I3
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1136941:ACH46 RS18965
gene id: 1136941:ACH46_RS18965
uniprot id: A0A0N9N5Q6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1136941:ACH46 RS10520
gene id: 1136941:ACH46_RS10520
uniprot id: A0A0N9NHD2
names: Similarity
messages: Belongs to the peptidase M24B family.

1136941:ACH46 RS02315
gene id: 1136941:ACH46_RS02315
uniprot id: A0A0N9N8H3
names: Similarity
messages: Belongs to the barstar family.

1136941:ACH46 RS01625
gene id: 1136941:ACH46_RS01625
uniprot id: A0A0N9N049
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS09025
gene id: 1136941:ACH46_RS09025
uniprot id: A0A0N9N8W0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1136941:ACH46 RS19575
gene id: 1136941:ACH46_RS19575
uniprot id: A0A0N9N5Y4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.
messages: Involved in the hydrocarbon hydroxylating system, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase.

1136941:ACH46 RS04040
gene id: 1136941:ACH46_RS04040
uniprot id: A0A0N7FUA7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1136941:ACH46 RS19505
gene id: 1136941:ACH46_RS19505
uniprot id: A0A0N9NKN5
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS10065
gene id: 1136941:ACH46_RS10065
uniprot id: A0A0N9NGC9
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS17470
gene id: 1136941:ACH46_RS17470
uniprot id: A0A0N9NFU8
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS18955
gene id: 1136941:ACH46_RS18955
uniprot id: A0A0N7FVF8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS01320
gene id: 1136941:ACH46_RS01320
uniprot id: A0A0N9N015
names: Similarity
names: Subunit
messages: Belongs to the Bpa family.
messages: Forms a homooligomeric, either hexameric or heptameric, ring-like structure which stacks co-axially with the proteasomal alpha-rings.

1136941:ACH46 RS01800
gene id: 1136941:ACH46_RS01800
uniprot id: A0A0N9N8C9
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1136941:ACH46 RS17990
gene id: 1136941:ACH46_RS17990
uniprot id: A0A0N9NEA7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1136941:ACH46 RS11530
gene id: 1136941:ACH46_RS11530
uniprot id: A0A0N7FUQ4
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

1136941:ACH46 RS05720
gene id: 1136941:ACH46_RS05720
uniprot id: A0A0N9N7S4
names: Similarity
messages: Belongs to the UPF0145 family.

1136941:ACH46 RS04620
gene id: 1136941:ACH46_RS04620
uniprot id: A0A0N7FUB9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1136941:ACH46 RS12365
gene id: 1136941:ACH46_RS12365
uniprot id: A0A0N9MRQ2
names: Function
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.

1136941:ACH46 RS02235
gene id: 1136941:ACH46_RS02235
uniprot id: A0A0N9N8G6
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1136941:ACH46 RS04760
gene id: 1136941:ACH46_RS04760
uniprot id: A0A0N9N7G6
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

1136941:ACH46 RS14075
gene id: 1136941:ACH46_RS14075
uniprot id: A0A0N7FUV3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1136941:ACH46 RS03580
gene id: 1136941:ACH46_RS03580
uniprot id: A0A0N9MTT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1136941:ACH46 RS14145
gene id: 1136941:ACH46_RS14145
uniprot id: A0A0N9N4Q9
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1136941:ACH46 RS01905
gene id: 1136941:ACH46_RS01905
uniprot id: A0A0N7FU64
names: Similarity
messages: Belongs to the OsmC/Ohr family.

1136941:ACH46 RS04385
gene id: 1136941:ACH46_RS04385
uniprot id: A0A0N9N7B9
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

1136941:ACH46 RS05350
gene id: 1136941:ACH46_RS05350
uniprot id: A0A0N9NKP2
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.

1136941:ACH46 RS01815
gene id: 1136941:ACH46_RS01815
uniprot id: A0A0N9N8Q2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

1136941:ACH46 RS17605
gene id: 1136941:ACH46_RS17605
uniprot id: A0A0N9NJY8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1136941:ACH46 RS07915
gene id: 1136941:ACH46_RS07915
uniprot id: A0A0N9N2J1
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1136941:ACH46 RS11035
gene id: 1136941:ACH46_RS11035
uniprot id: A0A0N9NBE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arabinosyl transferase responsible for the polymerization of arabinose into the arabinan of arabinogalactan.
messages: Belongs to the emb family.
messages: Cell membrane
messages: Membrane

1136941:ACH46 RS03710
gene id: 1136941:ACH46_RS03710
uniprot id: A0A0N9N8X9
names: Function
names: Similarity
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

1136941:ACH46 RS20065
gene id: 1136941:ACH46_RS20065
uniprot id: A0A0N9MTB4
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS08455
gene id: 1136941:ACH46_RS08455
uniprot id: A0A0N9N1Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

1136941:ACH46 RS00865
gene id: 1136941:ACH46_RS00865
uniprot id: A0A0N9N8P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1136941:ACH46 RS16145
gene id: 1136941:ACH46_RS16145
uniprot id: A0A0N9NBE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1136941:ACH46 RS20220
gene id: 1136941:ACH46_RS20220
uniprot id: A0A0N9N715
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS06450
gene id: 1136941:ACH46_RS06450
uniprot id: A0A0N7FUF5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS00850
gene id: 1136941:ACH46_RS00850
uniprot id: A0A0N9MZU9
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

1136941:ACH46 RS01290
gene id: 1136941:ACH46_RS01290
uniprot id: A0A0N9NFM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

1136941:ACH46 RS13895
gene id: 1136941:ACH46_RS13895
uniprot id: A0A0N9NI39
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS12695
gene id: 1136941:ACH46_RS12695
uniprot id: A0A0N7FUS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

1136941:ACH46 RS13800
gene id: 1136941:ACH46_RS13800
uniprot id: A0A0N9NCE5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1136941:ACH46 RS02720
gene id: 1136941:ACH46_RS02720
uniprot id: A0A0N9N8L9
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1136941:ACH46 RS12820
gene id: 1136941:ACH46_RS12820
uniprot id: A0A0N9MQN4
names: Similarity
messages: Belongs to the glutamine synthetase family.

1136941:ACH46 RS07580
gene id: 1136941:ACH46_RS07580
uniprot id: A0A0N9NGB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1136941:ACH46 RS12675
gene id: 1136941:ACH46_RS12675
uniprot id: A0A0N9MQM2
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

1136941:ACH46 RS11905
gene id: 1136941:ACH46_RS11905
uniprot id: A0A0N9N7C0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1136941:ACH46 RS13995
gene id: 1136941:ACH46_RS13995
uniprot id: A0A0N9N4N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

1136941:ACH46 RS10275
gene id: 1136941:ACH46_RS10275
uniprot id: A0A0N9N9B7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS19000
gene id: 1136941:ACH46_RS19000
uniprot id: A0A0N9N6L7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

1136941:ACH46 RS07970
gene id: 1136941:ACH46_RS07970
uniprot id: A0A0N7FUI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1136941:ACH46 RS06780
gene id: 1136941:ACH46_RS06780
uniprot id: A0A0N9NG84
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1136941:ACH46 RS01445
gene id: 1136941:ACH46_RS01445
uniprot id: A0A0N9MLP0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1136941:ACH46 RS09735
gene id: 1136941:ACH46_RS09735
uniprot id: A0A0N9MVM5
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS09110
gene id: 1136941:ACH46_RS09110
uniprot id: A0A0N9NC47
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

1136941:ACH46 RS20425
gene id: 1136941:ACH46_RS20425
uniprot id: A0A0N9NK90
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS00010
gene id: 1136941:ACH46_RS00010
uniprot id: A0A0N9MYT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1136941:ACH46 RS02610
gene id: 1136941:ACH46_RS02610
uniprot id: A0A0N9NDJ0
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1136941:ACH46 RS08315
gene id: 1136941:ACH46_RS08315
uniprot id: A0A0N9NAN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1136941:ACH46 RS01770
gene id: 1136941:ACH46_RS01770
uniprot id: A0A0N9N086
names: Similarity
messages: Belongs to the CFA/CMAS family.

1136941:ACH46 RS06375
gene id: 1136941:ACH46_RS06375
uniprot id: A0A0N9NB18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

1136941:ACH46 RS05380
gene id: 1136941:ACH46_RS05380
uniprot id: A0A0N9N9G6
names: Similarity
messages: Belongs to the EccE family.

1136941:ACH46 RS20060
gene id: 1136941:ACH46_RS20060
uniprot id: A0A0N9NFA5
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

1136941:ACH46 RS11785
gene id: 1136941:ACH46_RS11785
uniprot id: A0A0N9N2Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1136941:ACH46 RS02320
gene id: 1136941:ACH46_RS02320
uniprot id: A0A0N9NE72
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

1136941:ACH46 RS11825
gene id: 1136941:ACH46_RS11825
uniprot id: A0A0N9N9U0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1136941:ACH46 RS09685
gene id: 1136941:ACH46_RS09685
uniprot id: A0A0N9NCD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

1136941:ACH46 RS15415
gene id: 1136941:ACH46_RS15415
uniprot id: A0A0N9MRJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1136941:ACH46 RS09655
gene id: 1136941:ACH46_RS09655
uniprot id: A0A0N7FUL7
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1136941:ACH46 RS03505
gene id: 1136941:ACH46_RS03505
uniprot id: A0A0N9N8V5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1136941:ACH46 RS03735
gene id: 1136941:ACH46_RS03735
uniprot id: A0A0N9MZV0
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS16680
gene id: 1136941:ACH46_RS16680
uniprot id: A0A0N7FV06
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

1136941:ACH46 RS17785
gene id: 1136941:ACH46_RS17785
uniprot id: A0A0N9NC21
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1136941:ACH46 RS17795
gene id: 1136941:ACH46_RS17795
uniprot id: A0A0N9MTU9
names: Similarity
messages: Belongs to the peptidase S13 family.

1136941:ACH46 RS17120
gene id: 1136941:ACH46_RS17120
uniprot id: A0A0N9NBT1
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

1136941:ACH46 RS03470
gene id: 1136941:ACH46_RS03470
uniprot id: A0A0N9N984
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1136941:ACH46 RS07815
gene id: 1136941:ACH46_RS07815
uniprot id: A0A0N9MNR7
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1136941:ACH46 RS16260
gene id: 1136941:ACH46_RS16260
uniprot id: A0A0N9NJF2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1136941:ACH46 RS14485
gene id: 1136941:ACH46_RS14485
uniprot id: A0A0N9NIT2
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

1136941:ACH46 RS03825
gene id: 1136941:ACH46_RS03825
uniprot id: A0A0N9MZV5
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

1136941:ACH46 RS10045
gene id: 1136941:ACH46_RS10045
uniprot id: A0A0N9NH75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1136941:ACH46 RS11640
gene id: 1136941:ACH46_RS11640
uniprot id: A0A0N9NGZ3
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1136941:ACH46 RS05220
gene id: 1136941:ACH46_RS05220
uniprot id: A0A0N9N9E9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1136941:ACH46 RS03325
gene id: 1136941:ACH46_RS03325
uniprot id: A0A0N9N969
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1136941:ACH46 RS19645
gene id: 1136941:ACH46_RS19645
uniprot id: A0A0N9NEZ6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1136941:ACH46 RS15245
gene id: 1136941:ACH46_RS15245
uniprot id: A0A0N9NI78
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

1136941:ACH46 RS10040
gene id: 1136941:ACH46_RS10040
uniprot id: A0A0N9NB22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1136941:ACH46 RS10010
gene id: 1136941:ACH46_RS10010
uniprot id: A0A0N9N986
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

1136941:ACH46 RS18870
gene id: 1136941:ACH46_RS18870
uniprot id: A0A0N9NGD7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1136941:ACH46 RS13755
gene id: 1136941:ACH46_RS13755
uniprot id: A0A0N9N3L0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1136941:ACH46 RS06685
gene id: 1136941:ACH46_RS06685
uniprot id: A0A0N9NFZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

1136941:ACH46 RS12680
gene id: 1136941:ACH46_RS12680
uniprot id: A0A0N9NHD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

1136941:ACH46 RS12380
gene id: 1136941:ACH46_RS12380
uniprot id: A0A0N9NI11
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1136941:ACH46 RS17490
gene id: 1136941:ACH46_RS17490
uniprot id: A0A0N9NE40
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1136941:ACH46 RS09665
gene id: 1136941:ACH46_RS09665
uniprot id: A0A0N9NG75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1136941:ACH46 RS08480
gene id: 1136941:ACH46_RS08480
uniprot id: A0A0N9NL05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1136941:ACH46 RS14160
gene id: 1136941:ACH46_RS14160
uniprot id: A0A0N9NE66
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS04795
gene id: 1136941:ACH46_RS04795
uniprot id: A0A0N9N089
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1136941:ACH46 RS05285
gene id: 1136941:ACH46_RS05285
uniprot id: A0A0N9NLG8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.
messages: Belongs to the MshB deacetylase family. Mca subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Monomer.

1136941:ACH46 RS01610
gene id: 1136941:ACH46_RS01610
uniprot id: A0A0N9N8N0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1136941:ACH46 RS16840
gene id: 1136941:ACH46_RS16840
uniprot id: A0A0N9NFK3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.

1136941:ACH46 RS11145
gene id: 1136941:ACH46_RS11145
uniprot id: A0A0N7FUP7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1136941:ACH46 RS18085
gene id: 1136941:ACH46_RS18085
uniprot id: A0A0N9MSI4
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS06220
gene id: 1136941:ACH46_RS06220
uniprot id: A0A0N9N7Y4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1136941:ACH46 RS16330
gene id: 1136941:ACH46_RS16330
uniprot id: A0A0N9NDI6
names: Similarity
messages: Belongs to the cytochrome P450 family.

1136941:ACH46 RS08780
gene id: 1136941:ACH46_RS08780
uniprot id: A0A0N9MP56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1136941:ACH46 RS20140
gene id: 1136941:ACH46_RS20140
uniprot id: A0A0N9N706
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS16605
gene id: 1136941:ACH46_RS16605
uniprot id: A0A0N9NBK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

1136941:ACH46 RS16320
gene id: 1136941:ACH46_RS16320
uniprot id: A0A0N9NJG1
names: Similarity
messages: Belongs to the cytochrome P450 family.

1136941:ACH46 RS10145
gene id: 1136941:ACH46_RS10145
uniprot id: A0A0N9MQW7
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1136941:ACH46 RS08725
gene id: 1136941:ACH46_RS08725
uniprot id: A0A0N9N8S3
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS08435
gene id: 1136941:ACH46_RS08435
uniprot id: A0A0N9NBY3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

1136941:ACH46 RS19880
gene id: 1136941:ACH46_RS19880
uniprot id: A0A0N7FV70
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1136941:ACH46 RS09675
gene id: 1136941:ACH46_RS09675
uniprot id: A0A0N9N944
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1136941:ACH46 RS09680
gene id: 1136941:ACH46_RS09680
uniprot id: A0A0N9MQQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1136941:ACH46 RS16495
gene id: 1136941:ACH46_RS16495
uniprot id: A0A0N9NLJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1136941:ACH46 RS03395
gene id: 1136941:ACH46_RS03395
uniprot id: A0A0N9MM55
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1136941:ACH46 RS09345
gene id: 1136941:ACH46_RS09345
uniprot id: A0A0N9NG37
names: Caution
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS06830
gene id: 1136941:ACH46_RS06830
uniprot id: A0A0N9NG17
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1136941:ACH46 RS09325
gene id: 1136941:ACH46_RS09325
uniprot id: A0A0N7FUL1
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1136941:ACH46 RS16075
gene id: 1136941:ACH46_RS16075
uniprot id: A0A0N9N5F0
names: Similarity
messages: Belongs to the CdaR family.

1136941:ACH46 RS03295
gene id: 1136941:ACH46_RS03295
uniprot id: A0A0N7FU92
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1136941:ACH46 RS12195
gene id: 1136941:ACH46_RS12195
uniprot id: A0A0N9N9Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1136941:ACH46 RS08765
gene id: 1136941:ACH46_RS08765
uniprot id: A0A0N9N1U6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1136941:ACH46 RS12445
gene id: 1136941:ACH46_RS12445
uniprot id: A0A0N9NI19
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1136941:ACH46 RS05695
gene id: 1136941:ACH46_RS05695
uniprot id: A0A0N9MMZ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS08225
gene id: 1136941:ACH46_RS08225
uniprot id: A0A0N9NBV2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1136941:ACH46 RS03130
gene id: 1136941:ACH46_RS03130
uniprot id: A0A0N9MZP7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1136941:ACH46 RS15540
gene id: 1136941:ACH46_RS15540
uniprot id: A0A0N9NJ57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

1136941:ACH46 RS16195
gene id: 1136941:ACH46_RS16195
uniprot id: A0A0N9NIA1
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS20635
gene id: 1136941:ACH46_RS20635
uniprot id: A0A0N9NHG4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1136941:ACH46 RS14435
gene id: 1136941:ACH46_RS14435
uniprot id: A0A0N7FUW0
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1136941:ACH46 RS06455
gene id: 1136941:ACH46_RS06455
uniprot id: A0A0N9N9U2
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS15370
gene id: 1136941:ACH46_RS15370
uniprot id: A0A0N9NB34
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

1136941:ACH46 RS14945
gene id: 1136941:ACH46_RS14945
uniprot id: A0A0N7FUX0
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

1136941:ACH46 RS03965
gene id: 1136941:ACH46_RS03965
uniprot id: A0A0N9MZY6
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

1136941:ACH46 RS12485
gene id: 1136941:ACH46_RS12485
uniprot id: A0A0N9NA14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1136941:ACH46 RS19490
gene id: 1136941:ACH46_RS19490
uniprot id: A0A0N7FV62
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS18550
gene id: 1136941:ACH46_RS18550
uniprot id: A0A0N7FV44
names: Similarity
messages: Belongs to the leucine-binding protein family.

1136941:ACH46 RS20025
gene id: 1136941:ACH46_RS20025
uniprot id: A0A0N9MUR4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1136941:ACH46 RS02715
gene id: 1136941:ACH46_RS02715
uniprot id: A0A0N9N9F0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

1136941:ACH46 RS13115
gene id: 1136941:ACH46_RS13115
uniprot id: A0A0N9NIB3
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS05215
gene id: 1136941:ACH46_RS05215
uniprot id: A0A0N9NAI8
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS08550
gene id: 1136941:ACH46_RS08550
uniprot id: A0A0N9MP27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1136941:ACH46 RS10075
gene id: 1136941:ACH46_RS10075
uniprot id: A0A0N9MVN1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1136941:ACH46 RS10465
gene id: 1136941:ACH46_RS10465
uniprot id: A0A0N9NBE5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

1136941:ACH46 RS09845
gene id: 1136941:ACH46_RS09845
uniprot id: A0A0N7FUM1
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS20525
gene id: 1136941:ACH46_RS20525
uniprot id: A0A0N9ND74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

1136941:ACH46 RS15475
gene id: 1136941:ACH46_RS15475
uniprot id: A0A0N9ND61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1136941:ACH46 RS12070
gene id: 1136941:ACH46_RS12070
uniprot id: A0A0N9N816
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1136941:ACH46 RS04020
gene id: 1136941:ACH46_RS04020
uniprot id: A0A0N9N908
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

1136941:ACH46 RS04085
gene id: 1136941:ACH46_RS04085
uniprot id: A0A0N7FUA8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1136941:ACH46 RS12930
gene id: 1136941:ACH46_RS12930
uniprot id: A0A0N9NA69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Membrane

1136941:ACH46 RS17900
gene id: 1136941:ACH46_RS17900
uniprot id: A0A0N9NJA0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1136941:ACH46 RS09305
gene id: 1136941:ACH46_RS09305
uniprot id: A0A0N9MQM7
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1136941:ACH46 RS07935
gene id: 1136941:ACH46_RS07935
uniprot id: A0A0N9NBQ0
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

1136941:ACH46 RS04615
gene id: 1136941:ACH46_RS04615
uniprot id: A0A0N9N7E6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS19525
gene id: 1136941:ACH46_RS19525
uniprot id: A0A0N9NJW3
names: Similarity
messages: Belongs to the peptidase M13 family.

1136941:ACH46 RS08370
gene id: 1136941:ACH46_RS08370
uniprot id: A0A0N9NGL6
names: Similarity
messages: Belongs to the acylphosphatase family.

1136941:ACH46 RS06995
gene id: 1136941:ACH46_RS06995
uniprot id: A0A0N9NA09
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

1136941:ACH46 RS15840
gene id: 1136941:ACH46_RS15840
uniprot id: A0A0N7FUY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1136941:ACH46 RS04685
gene id: 1136941:ACH46_RS04685
uniprot id: A0A0N9MP55
names: Similarity
messages: Belongs to the ArsC family.

1136941:ACH46 RS03350
gene id: 1136941:ACH46_RS03350
uniprot id: A0A0N9N711
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1136941:ACH46 RS17865
gene id: 1136941:ACH46_RS17865
uniprot id: A0A0N9NFZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1136941:ACH46 RS02120
gene id: 1136941:ACH46_RS02120
uniprot id: A0A0N9MLT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

1136941:ACH46 RS18315
gene id: 1136941:ACH46_RS18315
uniprot id: A0A0N9NEI1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1136941:ACH46 RS05915
gene id: 1136941:ACH46_RS05915
uniprot id: A0A0N7FUE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

1136941:ACH46 RS04290
gene id: 1136941:ACH46_RS04290
uniprot id: A0A0N9NF48
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1136941:ACH46 RS17870
gene id: 1136941:ACH46_RS17870
uniprot id: A0A0N9NE86
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1136941:ACH46 RS11015
gene id: 1136941:ACH46_RS11015
uniprot id: A0A0N9N9L0
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS19500
gene id: 1136941:ACH46_RS19500
uniprot id: A0A0N9NEX0
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS12205
gene id: 1136941:ACH46_RS12205
uniprot id: A0A0N9MRN5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1136941:ACH46 RS00005
gene id: 1136941:ACH46_RS00005
uniprot id: A0A0N9NDL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1136941:ACH46 RS06115
gene id: 1136941:ACH46_RS06115
uniprot id: A0A0N7FUE8
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1136941:ACH46 RS09410
gene id: 1136941:ACH46_RS09410
uniprot id: A0A0N9NLT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

1136941:ACH46 RS14560
gene id: 1136941:ACH46_RS14560
uniprot id: A0A0N9NEC0
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

1136941:ACH46 RS12575
gene id: 1136941:ACH46_RS12575
uniprot id: A0A0N9NDJ9
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

1136941:ACH46 RS01055
gene id: 1136941:ACH46_RS01055
uniprot id: A0A0N9MZX1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

1136941:ACH46 RS07325
gene id: 1136941:ACH46_RS07325
uniprot id: A0A0N9N8A9
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

1136941:ACH46 RS09010
gene id: 1136941:ACH46_RS09010
uniprot id: A0A0N9MP98
names: Similarity
messages: Belongs to the PspA/IM30 family.

1136941:ACH46 RS19670
gene id: 1136941:ACH46_RS19670
uniprot id: A0A0N9MT38
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS01130
gene id: 1136941:ACH46_RS01130
uniprot id: A0A0N9N8T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1136941:ACH46 RS17675
gene id: 1136941:ACH46_RS17675
uniprot id: A0A0N9NJZ5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1136941:ACH46 RS06360
gene id: 1136941:ACH46_RS06360
uniprot id: A0A0N9N219
names: Similarity
messages: Belongs to the DSD1 family.

1136941:ACH46 RS16250
gene id: 1136941:ACH46_RS16250
uniprot id: A0A0N9NDI9
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family.

1136941:ACH46 RS18540
gene id: 1136941:ACH46_RS18540
uniprot id: A0A0N9NKA2
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1136941:ACH46 RS13760
gene id: 1136941:ACH46_RS13760
uniprot id: A0A0N9NCH3
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

1136941:ACH46 RS02065
gene id: 1136941:ACH46_RS02065
uniprot id: A0A0N9NDB0
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS19855
gene id: 1136941:ACH46_RS19855
uniprot id: A0A0N9NF24
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

1136941:ACH46 RS20365
gene id: 1136941:ACH46_RS20365
uniprot id: A0A0N9MUV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1136941:ACH46 RS03425
gene id: 1136941:ACH46_RS03425
uniprot id: A0A0N9N716
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

1136941:ACH46 RS11815
gene id: 1136941:ACH46_RS11815
uniprot id: A0A0N9NH10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1136941:ACH46 RS09660
gene id: 1136941:ACH46_RS09660
uniprot id: A0A0N9MPH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

1136941:ACH46 RS16880
gene id: 1136941:ACH46_RS16880
uniprot id: A0A0N9NDQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1136941:ACH46 RS17630
gene id: 1136941:ACH46_RS17630
uniprot id: A0A0N9N618
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1136941:ACH46 RS13820
gene id: 1136941:ACH46_RS13820
uniprot id: A0A0N9N3L8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1136941:ACH46 RS04670
gene id: 1136941:ACH46_RS04670
uniprot id: A0A0N9NEC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1136941:ACH46 RS12740
gene id: 1136941:ACH46_RS12740
uniprot id: A0A0N9MQM6
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1136941:ACH46 RS12300
gene id: 1136941:ACH46_RS12300
uniprot id: A0A0N9NBV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1136941:ACH46 RS05690
gene id: 1136941:ACH46_RS05690
uniprot id: A0A0N9N9X3
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

1136941:ACH46 RS05400
gene id: 1136941:ACH46_RS05400
uniprot id: A0A0N9N9U1
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

1136941:ACH46 RS11960
gene id: 1136941:ACH46_RS11960
uniprot id: A0A0N9N9V6
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

1136941:ACH46 RS15470
gene id: 1136941:ACH46_RS15470
uniprot id: A0A0N9N488
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1136941:ACH46 RS06705
gene id: 1136941:ACH46_RS06705
uniprot id: A0A0N9NA81
names: Similarity
messages: Belongs to the PrpD family.

1136941:ACH46 RS14470
gene id: 1136941:ACH46_RS14470
uniprot id: A0A0N9NEA6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1136941:ACH46 RS14480
gene id: 1136941:ACH46_RS14480
uniprot id: A0A0N9NEP4
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1136941:ACH46 RS08990
gene id: 1136941:ACH46_RS08990
uniprot id: A0A0N9NGT9
names: Similarity
messages: Belongs to the YciI family.

1136941:ACH46 RS17145
gene id: 1136941:ACH46_RS17145
uniprot id: A0A0N9NDX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1136941:ACH46 RS00915
gene id: 1136941:ACH46_RS00915
uniprot id: A0A0N9MLK6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1136941:ACH46 RS02225
gene id: 1136941:ACH46_RS02225
uniprot id: A0A0N9MN86
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1136941:ACH46 RS07800
gene id: 1136941:ACH46_RS07800
uniprot id: A0A0N7FUI1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1136941:ACH46 RS02435
gene id: 1136941:ACH46_RS02435
uniprot id: A0A0N7FU75
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1136941:ACH46 RS02275
gene id: 1136941:ACH46_RS02275
uniprot id: A0A0N9MLV9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F420-dependent glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone.
messages: Homodimer.

1136941:ACH46 RS08215
gene id: 1136941:ACH46_RS08215
uniprot id: A0A0N7FUI9
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS17775
gene id: 1136941:ACH46_RS17775
uniprot id: A0A0N9NJ87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

1136941:ACH46 RS14035
gene id: 1136941:ACH46_RS14035
uniprot id: A0A0N9NCH9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1136941:ACH46 RS09740
gene id: 1136941:ACH46_RS09740
uniprot id: A0A0N9N953
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

1136941:ACH46 RS18325
gene id: 1136941:ACH46_RS18325
uniprot id: A0A0N7FV40
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1136941:ACH46 RS02200
gene id: 1136941:ACH46_RS02200
uniprot id: A0A0N9MLV0
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

1136941:ACH46 RS19420
gene id: 1136941:ACH46_RS19420
uniprot id: A0A0N9NKM7
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1136941:ACH46 RS15590
gene id: 1136941:ACH46_RS15590
uniprot id: A0A0N9NET7
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1136941:ACH46 RS13655
gene id: 1136941:ACH46_RS13655
uniprot id: A0A0N9NAF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

1136941:ACH46 RS08275
gene id: 1136941:ACH46_RS08275
uniprot id: A0A0N9N2N2
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

1136941:ACH46 RS16185
gene id: 1136941:ACH46_RS16185
uniprot id: A0A0N9N4J7
names: Similarity
messages: Belongs to the DNA photolyase family.

1136941:ACH46 RS18410
gene id: 1136941:ACH46_RS18410
uniprot id: A0A0N9N6C1
names: Similarity
messages: Belongs to the thioesterase family.

1136941:ACH46 RS10675
gene id: 1136941:ACH46_RS10675
uniprot id: A0A0N9N2L0
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MbtB subfamily.

1136941:ACH46 RS02545
gene id: 1136941:ACH46_RS02545
uniprot id: A0A0N9N0J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1136941:ACH46 RS18335
gene id: 1136941:ACH46_RS18335
uniprot id: A0A0N9NJF5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1136941:ACH46 RS18125
gene id: 1136941:ACH46_RS18125
uniprot id: A0A0N9NG39
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1136941:ACH46 RS07250
gene id: 1136941:ACH46_RS07250
uniprot id: A0A0N9NE04
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS16655
gene id: 1136941:ACH46_RS16655
uniprot id: A0A0N9N4R2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1136941:ACH46 RS09280
gene id: 1136941:ACH46_RS09280
uniprot id: A0A0N9MPC7
names: Similarity
messages: Belongs to the AccD/PCCB family.

1136941:ACH46 RS13065
gene id: 1136941:ACH46_RS13065
uniprot id: A0A0N9MVV2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1136941:ACH46 RS03450
gene id: 1136941:ACH46_RS03450
uniprot id: A0A0N7FU95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1136941:ACH46 RS11285
gene id: 1136941:ACH46_RS11285
uniprot id: A0A0N9MQ66
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1136941:ACH46 RS19785
gene id: 1136941:ACH46_RS19785
uniprot id: A0A0N7FV68
names: Similarity
messages: Belongs to the CsoR family.

1136941:ACH46 RS03915
gene id: 1136941:ACH46_RS03915
uniprot id: A0A0N9NE07
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS10570
gene id: 1136941:ACH46_RS10570
uniprot id: A0A0N9N9F5
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

1136941:ACH46 RS11165
gene id: 1136941:ACH46_RS11165
uniprot id: A0A0N9N9M4
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

1136941:ACH46 RS16425
gene id: 1136941:ACH46_RS16425
uniprot id: A0A0N9NFD2
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1136941:ACH46 RS14200
gene id: 1136941:ACH46_RS14200
uniprot id: A0A0N9NHW6
names: Similarity
messages: Belongs to the HIBADH-related family.

1136941:ACH46 RS11740
gene id: 1136941:ACH46_RS11740
uniprot id: A0A0N9MVS2
names: Similarity
messages: Belongs to the TlyA family.

1136941:ACH46 RS13320
gene id: 1136941:ACH46_RS13320
uniprot id: A0A0N7FUT8
names: Similarity
messages: Belongs to the IMPACT family.

1136941:ACH46 RS04395
gene id: 1136941:ACH46_RS04395
uniprot id: A0A0N9NA64
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1136941:ACH46 RS08290
gene id: 1136941:ACH46_RS08290
uniprot id: A0A0N9NBW0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

1136941:ACH46 RS04050
gene id: 1136941:ACH46_RS04050
uniprot id: A0A0N9NE32
names: Similarity
messages: Belongs to the FPG family.

1136941:ACH46 RS13920
gene id: 1136941:ACH46_RS13920
uniprot id: A0A0N9NHS5
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1136941:ACH46 RS05710
gene id: 1136941:ACH46_RS05710
uniprot id: A0A0N9N1S7
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

1136941:ACH46 RS01820
gene id: 1136941:ACH46_RS01820
uniprot id: A0A0N9MLR2
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS01195
gene id: 1136941:ACH46_RS01195
uniprot id: A0A0N9N8T8
names: Similarity
messages: Belongs to the AccD/PCCB family.

1136941:ACH46 RS01105
gene id: 1136941:ACH46_RS01105
uniprot id: A0A0N9NCZ6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1136941:ACH46 RS01635
gene id: 1136941:ACH46_RS01635
uniprot id: A0A0N7FU59
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1136941:ACH46 RS01670
gene id: 1136941:ACH46_RS01670
uniprot id: A0A0N9MLQ1
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1136941:ACH46 RS01615
gene id: 1136941:ACH46_RS01615
uniprot id: A0A0N9MLP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1136941:ACH46 RS17915
gene id: 1136941:ACH46_RS17915
uniprot id: A0A0N9MTX0
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and hydrogenobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of hydrogenobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CobB catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

1136941:ACH46 RS00030
gene id: 1136941:ACH46_RS00030
uniprot id: A0A0N9MLE9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1136941:ACH46 RS20580
gene id: 1136941:ACH46_RS20580
uniprot id: A0A0N9ND81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1136941:ACH46 RS19360
gene id: 1136941:ACH46_RS19360
uniprot id: A0A0N9MT02
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1136941:ACH46 RS16640
gene id: 1136941:ACH46_RS16640
uniprot id: A0A0N7FV05
names: Similarity
messages: Belongs to the UPF0234 family.

1136941:ACH46 RS11860
gene id: 1136941:ACH46_RS11860
uniprot id: A0A0N9N303
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1136941:ACH46 RS13845
gene id: 1136941:ACH46_RS13845
uniprot id: A0A0N9N4L7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1136941:ACH46 RS11360
gene id: 1136941:ACH46_RS11360
uniprot id: A0A0N9N2U9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1136941:ACH46 RS16835
gene id: 1136941:ACH46_RS16835
uniprot id: A0A0N9MTF9
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS01735
gene id: 1136941:ACH46_RS01735
uniprot id: A0A0N7FU61
names: Similarity
messages: Belongs to the TPP enzyme family.

1136941:ACH46 RS08265
gene id: 1136941:ACH46_RS08265
uniprot id: A0A0N9NFR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1136941:ACH46 RS13625
gene id: 1136941:ACH46_RS13625
uniprot id: A0A0N7FUU4
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

1136941:ACH46 RS05420
gene id: 1136941:ACH46_RS05420
uniprot id: A0A0N9N1P5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1136941:ACH46 RS06105
gene id: 1136941:ACH46_RS06105
uniprot id: A0A0N9N9P6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1136941:ACH46 RS08810
gene id: 1136941:ACH46_RS08810
uniprot id: A0A0N9NC19
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1136941:ACH46 RS15390
gene id: 1136941:ACH46_RS15390
uniprot id: A0A0N9NEQ3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

1136941:ACH46 RS04205
gene id: 1136941:ACH46_RS04205
uniprot id: A0A0N9NA31
names: Similarity
messages: Belongs to the UPF0225 family.

1136941:ACH46 RS18650
gene id: 1136941:ACH46_RS18650
uniprot id: A0A0N9NCE2
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

1136941:ACH46 RS12550
gene id: 1136941:ACH46_RS12550
uniprot id: A0A0N9NHA8
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

1136941:ACH46 RS09895
gene id: 1136941:ACH46_RS09895
uniprot id: A0A0N9MQU1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1136941:ACH46 RS15060
gene id: 1136941:ACH46_RS15060
uniprot id: A0A0N9NCX6
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1136941:ACH46 RS09210
gene id: 1136941:ACH46_RS09210
uniprot id: A0A0N9NG20
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1136941:ACH46 RS14580
gene id: 1136941:ACH46_RS14580
uniprot id: A0A0N9NCT3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1136941:ACH46 RS06560
gene id: 1136941:ACH46_RS06560
uniprot id: A0A0N9N237
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

1136941:ACH46 RS15450
gene id: 1136941:ACH46_RS15450
uniprot id: A0A0N9NER6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1136941:ACH46 RS02375
gene id: 1136941:ACH46_RS02375
uniprot id: A0A0N9NFQ6
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS13165
gene id: 1136941:ACH46_RS13165
uniprot id: A0A0N9NDV0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1136941:ACH46 RS11220
gene id: 1136941:ACH46_RS11220
uniprot id: A0A0N9N9N3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1136941:ACH46 RS09370
gene id: 1136941:ACH46_RS09370
uniprot id: A0A0N9MQN3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

1136941:ACH46 RS13005
gene id: 1136941:ACH46_RS13005
uniprot id: A0A0N9NA79
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Acyl carrier protein involved in meromycolate extension.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1136941:ACH46 RS17835
gene id: 1136941:ACH46_RS17835
uniprot id: A0A0N9MSE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

1136941:ACH46 RS05320
gene id: 1136941:ACH46_RS05320
uniprot id: A0A0N9MMU6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS16710
gene id: 1136941:ACH46_RS16710
uniprot id: A0A0N9NDR3
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

1136941:ACH46 RS07495
gene id: 1136941:ACH46_RS07495
uniprot id: A0A0N9NBI1
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

1136941:ACH46 RS20405
gene id: 1136941:ACH46_RS20405
uniprot id: A0A0N9NFG0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1136941:ACH46 RS20595
gene id: 1136941:ACH46_RS20595
uniprot id: A0A0N7FV85
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1136941:ACH46 RS08400
gene id: 1136941:ACH46_RS08400
uniprot id: A0A0N7FUJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

1136941:ACH46 RS02530
gene id: 1136941:ACH46_RS02530
uniprot id: A0A0N7FU77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1136941:ACH46 RS08620
gene id: 1136941:ACH46_RS08620
uniprot id: A0A0N9NG51
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1136941:ACH46 RS04285
gene id: 1136941:ACH46_RS04285
uniprot id: A0A0N9N943
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1136941:ACH46 RS01860
gene id: 1136941:ACH46_RS01860
uniprot id: A0A0N9N6L2
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS02360
gene id: 1136941:ACH46_RS02360
uniprot id: A0A0N9MNB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1136941:ACH46 RS06910
gene id: 1136941:ACH46_RS06910
uniprot id: A0A0N9N9Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1136941:ACH46 RS08630
gene id: 1136941:ACH46_RS08630
uniprot id: A0A0N9MP33
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

1136941:ACH46 RS16930
gene id: 1136941:ACH46_RS16930
uniprot id: A0A0N9NFL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

1136941:ACH46 RS09695
gene id: 1136941:ACH46_RS09695
uniprot id: A0A0N7FUL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1136941:ACH46 RS04875
gene id: 1136941:ACH46_RS04875
uniprot id: A0A0N9MV98
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DyP-type peroxidase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.

1136941:ACH46 RS08920
gene id: 1136941:ACH46_RS08920
uniprot id: A0A0N9NAN3
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

1136941:ACH46 RS15660
gene id: 1136941:ACH46_RS15660
uniprot id: A0A0N9MT05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1136941:ACH46 RS10935
gene id: 1136941:ACH46_RS10935
uniprot id: A0A0N9NBJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1136941:ACH46 RS07810
gene id: 1136941:ACH46_RS07810
uniprot id: A0A0N9NAI0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1136941:ACH46 RS06030
gene id: 1136941:ACH46_RS06030
uniprot id: A0A0N9MPM0
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

1136941:ACH46 RS05045
gene id: 1136941:ACH46_RS05045
uniprot id: A0A0N9N9D0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1136941:ACH46 RS15465
gene id: 1136941:ACH46_RS15465
uniprot id: A0A0N7FUY1
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1136941:ACH46 RS12925
gene id: 1136941:ACH46_RS12925
uniprot id: A0A0N9N4B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

1136941:ACH46 RS06160
gene id: 1136941:ACH46_RS06160
uniprot id: A0A0N9MPN6
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1136941:ACH46 RS17280
gene id: 1136941:ACH46_RS17280
uniprot id: A0A0N7FV18
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

1136941:ACH46 RS04995
gene id: 1136941:ACH46_RS04995
uniprot id: A0A0N9NFC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

1136941:ACH46 RS07425
gene id: 1136941:ACH46_RS07425
uniprot id: A0A0N9NG99
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1136941:ACH46 RS15255
gene id: 1136941:ACH46_RS15255
uniprot id: A0A0N9MSU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1136941:ACH46 RS07775
gene id: 1136941:ACH46_RS07775
uniprot id: A0A0N9N8G2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1136941:ACH46 RS00840
gene id: 1136941:ACH46_RS00840
uniprot id: A0A0N9NCV8
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

1136941:ACH46 RS20570
gene id: 1136941:ACH46_RS20570
uniprot id: A0A0N9NKA8
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

1136941:ACH46 RS09135
gene id: 1136941:ACH46_RS09135
uniprot id: A0A0N9NAX6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1136941:ACH46 RS10430
gene id: 1136941:ACH46_RS10430
uniprot id: A0A0N9MQZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1136941:ACH46 RS05540
gene id: 1136941:ACH46_RS05540
uniprot id: A0A0N9NAM5
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

1136941:ACH46 RS14180
gene id: 1136941:ACH46_RS14180
uniprot id: A0A0N9NIQ0
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS04700
gene id: 1136941:ACH46_RS04700
uniprot id: A0A0N9NF88
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS13765
gene id: 1136941:ACH46_RS13765
uniprot id: A0A0N7FUU7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1136941:ACH46 RS09160
gene id: 1136941:ACH46_RS09160
uniprot id: A0A0N9N2W6
names: Function
names: Similarity
names: Subunit
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.
messages: Homotrimer.

1136941:ACH46 RS15295
gene id: 1136941:ACH46_RS15295
uniprot id: A0A0N9MRH7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1136941:ACH46 RS13890
gene id: 1136941:ACH46_RS13890
uniprot id: A0A0N9NIL1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1136941:ACH46 RS19980
gene id: 1136941:ACH46_RS19980
uniprot id: A0A0N9NF56
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1136941:ACH46 RS13720
gene id: 1136941:ACH46_RS13720
uniprot id: A0A0N7FUU6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

1136941:ACH46 RS06230
gene id: 1136941:ACH46_RS06230
uniprot id: A0A0N9MPP2
names: Similarity
messages: Belongs to the cytochrome P450 family.

1136941:ACH46 RS04280
gene id: 1136941:ACH46_RS04280
uniprot id: A0A0N9NA42
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1136941:ACH46 RS13040
gene id: 1136941:ACH46_RS13040
uniprot id: A0A0N9N3C8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1136941:ACH46 RS17800
gene id: 1136941:ACH46_RS17800
uniprot id: A0A0N9NFY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1136941:ACH46 RS11900
gene id: 1136941:ACH46_RS11900
uniprot id: A0A0N9N9V0
names: Similarity
messages: Belongs to the universal stress protein A family.

1136941:ACH46 RS10105
gene id: 1136941:ACH46_RS10105
uniprot id: A0A0N9NH84
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS18030
gene id: 1136941:ACH46_RS18030
uniprot id: A0A0N9NJB6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

1136941:ACH46 RS00945
gene id: 1136941:ACH46_RS00945
uniprot id: A0A0N7FU45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cutinase family.
messages: Catalyzes the hydrolysis of complex carboxylic polyesters found in the cell wall of plants. Degrades cutin, a macromolecule that forms the structure of the plant cuticle.
messages: Secreted

1136941:ACH46 RS08740
gene id: 1136941:ACH46_RS08740
uniprot id: A0A0N9NC12
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS02970
gene id: 1136941:ACH46_RS02970
uniprot id: A0A0N9MNJ3
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS12585
gene id: 1136941:ACH46_RS12585
uniprot id: A0A0N9NI36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

1136941:ACH46 RS06240
gene id: 1136941:ACH46_RS06240
uniprot id: A0A0N9N9R1
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1136941:ACH46 RS08280
gene id: 1136941:ACH46_RS08280
uniprot id: A0A0N9N8L7
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

1136941:ACH46 RS13985
gene id: 1136941:ACH46_RS13985
uniprot id: A0A0N9MR42
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1136941:ACH46 RS07830
gene id: 1136941:ACH46_RS07830
uniprot id: A0A0N9N2I2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1136941:ACH46 RS07615
gene id: 1136941:ACH46_RS07615
uniprot id: A0A0N9MNP2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1136941:ACH46 RS12420
gene id: 1136941:ACH46_RS12420
uniprot id: A0A0N9N426
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1136941:ACH46 RS08260
gene id: 1136941:ACH46_RS08260
uniprot id: A0A0N7FUJ0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1136941:ACH46 RS07715
gene id: 1136941:ACH46_RS07715
uniprot id: A0A0N9NBL3
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS13015
gene id: 1136941:ACH46_RS13015
uniprot id: A0A0N7FUT2
names: Similarity
messages: Belongs to the AccD/PCCB family.

1136941:ACH46 RS12400
gene id: 1136941:ACH46_RS12400
uniprot id: A0A0N9MQI7
names: Similarity
messages: Belongs to the asparaginase 1 family.

1136941:ACH46 RS03100
gene id: 1136941:ACH46_RS03100
uniprot id: A0A0N9N6Y7
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

1136941:ACH46 RS13545
gene id: 1136941:ACH46_RS13545
uniprot id: A0A0N9NIG8
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS09670
gene id: 1136941:ACH46_RS09670
uniprot id: A0A0N9N336
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1136941:ACH46 RS02450
gene id: 1136941:ACH46_RS02450
uniprot id: A0A0N9N6H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1136941:ACH46 RS04765
gene id: 1136941:ACH46_RS04765
uniprot id: A0A0N9MP62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

1136941:ACH46 RS08805
gene id: 1136941:ACH46_RS08805
uniprot id: A0A0N9MQG4
names: Similarity
messages: Belongs to the neutral ceramidase family.

1136941:ACH46 RS07805
gene id: 1136941:ACH46_RS07805
uniprot id: A0A0N9N1D5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1136941:ACH46 RS12610
gene id: 1136941:ACH46_RS12610
uniprot id: A0A0N9NHC7
names: Similarity
messages: Belongs to the peptidase S8 family.

1136941:ACH46 RS12125
gene id: 1136941:ACH46_RS12125
uniprot id: A0A0N9N9X0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1136941:ACH46 RS15145
gene id: 1136941:ACH46_RS15145
uniprot id: A0A0N9ND12
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1136941:ACH46 RS06980
gene id: 1136941:ACH46_RS06980
uniprot id: A0A0N9NBB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1136941:ACH46 RS12640
gene id: 1136941:ACH46_RS12640
uniprot id: A0A0N9MRU5
names: Similarity
messages: Belongs to the peptidase C40 family.

1136941:ACH46 RS19750
gene id: 1136941:ACH46_RS19750
uniprot id: A0A0N9MT48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1136941:ACH46 RS10575
gene id: 1136941:ACH46_RS10575
uniprot id: A0A0N9MR16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

1136941:ACH46 RS02405
gene id: 1136941:ACH46_RS02405
uniprot id: A0A0N9MLW9
names: Similarity
messages: Belongs to the AAA ATPase family.

1136941:ACH46 RS12110
gene id: 1136941:ACH46_RS12110
uniprot id: A0A0N9MQG7
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

1136941:ACH46 RS05865
gene id: 1136941:ACH46_RS05865
uniprot id: A0A0N9N7U6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MshB deacetylase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.

1136941:ACH46 RS16085
gene id: 1136941:ACH46_RS16085
uniprot id: A0A0N9MT63
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1136941:ACH46 RS18050
gene id: 1136941:ACH46_RS18050
uniprot id: A0A0N9MTZ1
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

1136941:ACH46 RS19860
gene id: 1136941:ACH46_RS19860
uniprot id: A0A0N9NKS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the encapsulin family. Family 1 subfamily.
messages: Encapsulin nanocompartment

1136941:ACH46 RS09395
gene id: 1136941:ACH46_RS09395
uniprot id: A0A0N9N232
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

1136941:ACH46 RS18630
gene id: 1136941:ACH46_RS18630
uniprot id: A0A0N9NJJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1136941:ACH46 RS03495
gene id: 1136941:ACH46_RS03495
uniprot id: A0A0N9MNT4
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

1136941:ACH46 RS02145
gene id: 1136941:ACH46_RS02145
uniprot id: A0A0N9MTP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1136941:ACH46 RS03370
gene id: 1136941:ACH46_RS03370
uniprot id: A0A0N9NEN4
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

1136941:ACH46 RS05195
gene id: 1136941:ACH46_RS05195
uniprot id: A0A0N9N1L2
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS07785
gene id: 1136941:ACH46_RS07785
uniprot id: A0A0N9NBM2
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS12745
gene id: 1136941:ACH46_RS12745
uniprot id: A0A0N9NHE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1136941:ACH46 RS17270
gene id: 1136941:ACH46_RS17270
uniprot id: A0A0N9NMC7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.
messages: Homooctamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions.

1136941:ACH46 RS14185
gene id: 1136941:ACH46_RS14185
uniprot id: A0A0N9N3R6
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

1136941:ACH46 RS01760
gene id: 1136941:ACH46_RS01760
uniprot id: A0A0N9MLQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

1136941:ACH46 RS13690
gene id: 1136941:ACH46_RS13690
uniprot id: A0A0N9N3K1
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1136941:ACH46 RS19700
gene id: 1136941:ACH46_RS19700
uniprot id: A0A0N9NCU5
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

1136941:ACH46 RS18790
gene id: 1136941:ACH46_RS18790
uniprot id: A0A0N9MU90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1136941:ACH46 RS14115
gene id: 1136941:ACH46_RS14115
uniprot id: A0A0N9N3Q2
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

1136941:ACH46 RS09850
gene id: 1136941:ACH46_RS09850
uniprot id: A0A0N7FVC4
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1136941:ACH46 RS12305
gene id: 1136941:ACH46_RS12305
uniprot id: A0A0N7FUR8
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

1136941:ACH46 RS09200
gene id: 1136941:ACH46_RS09200
uniprot id: A0A0N9NAY8
names: Similarity
messages: Belongs to the histone deacetylase family.

1136941:ACH46 RS13565
gene id: 1136941:ACH46_RS13565
uniprot id: A0A0N9MQZ6
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1136941:ACH46 RS04265
gene id: 1136941:ACH46_RS04265
uniprot id: A0A0N9MP07
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS07985
gene id: 1136941:ACH46_RS07985
uniprot id: A0A0N9NFM5
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1136941:ACH46 RS08700
gene id: 1136941:ACH46_RS08700
uniprot id: A0A0N9NL15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1136941:ACH46 RS00440
gene id: 1136941:ACH46_RS00440
uniprot id: A0A0N9NDP5
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS13615
gene id: 1136941:ACH46_RS13615
uniprot id: A0A0N9NIH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1136941:ACH46 RS06065
gene id: 1136941:ACH46_RS06065
uniprot id: A0A0N9MN50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Cell membrane
messages: Membrane

1136941:ACH46 RS01005
gene id: 1136941:ACH46_RS01005
uniprot id: A0A0N9MMP5
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1136941:ACH46 RS17850
gene id: 1136941:ACH46_RS17850
uniprot id: A0A0N9N642
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1136941:ACH46 RS07840
gene id: 1136941:ACH46_RS07840
uniprot id: A0A0N9MQ53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1136941:ACH46 RS12545
gene id: 1136941:ACH46_RS12545
uniprot id: A0A0N9MQK1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1136941:ACH46 RS09690
gene id: 1136941:ACH46_RS09690
uniprot id: A0A0N9NAX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1136941:ACH46 RS17245
gene id: 1136941:ACH46_RS17245
uniprot id: A0A0N9N5V8
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

1136941:ACH46 RS07235
gene id: 1136941:ACH46_RS07235
uniprot id: A0A0N9N2B3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1136941:ACH46 RS17695
gene id: 1136941:ACH46_RS17695
uniprot id: A0A0N7FV27
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1136941:ACH46 RS07740
gene id: 1136941:ACH46_RS07740
uniprot id: A0A0N9N1C2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1136941:ACH46 RS06045
gene id: 1136941:ACH46_RS06045
uniprot id: A0A0N9NFR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1136941:ACH46 RS19615
gene id: 1136941:ACH46_RS19615
uniprot id: A0A0N9MUJ9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1136941:ACH46 RS05725
gene id: 1136941:ACH46_RS05725
uniprot id: A0A0N9MPG4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1136941:ACH46 RS05850
gene id: 1136941:ACH46_RS05850
uniprot id: A0A0N9NEU1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1136941:ACH46 RS13070
gene id: 1136941:ACH46_RS13070
uniprot id: A0A0N9N4C9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS13735
gene id: 1136941:ACH46_RS13735
uniprot id: A0A0N9NE18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1136941:ACH46 RS00400
gene id: 1136941:ACH46_RS00400
uniprot id: A0A0N9MLG7
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1136941:ACH46 RS07330
gene id: 1136941:ACH46_RS07330
uniprot id: A0A0N9MQ04
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1136941:ACH46 RS14215
gene id: 1136941:ACH46_RS14215
uniprot id: A0A0N7FUV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. Mmr subfamily.
messages: Cell membrane
messages: Membrane

1136941:ACH46 RS17130
gene id: 1136941:ACH46_RS17130
uniprot id: A0A0N9NFP6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase group 1 family. MshA subfamily.
messages: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS02125
gene id: 1136941:ACH46_RS02125
uniprot id: A0A0N9NDC2
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

1136941:ACH46 RS07230
gene id: 1136941:ACH46_RS07230
uniprot id: A0A0N9NFC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1136941:ACH46 RS08200
gene id: 1136941:ACH46_RS08200
uniprot id: A0A0N9NFQ2
names: Similarity
messages: Belongs to the AccD/PCCB family.

1136941:ACH46 RS04560
gene id: 1136941:ACH46_RS04560
uniprot id: A0A0N7FUB8
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

1136941:ACH46 RS06185
gene id: 1136941:ACH46_RS06185
uniprot id: A0A0N9NA27
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1136941:ACH46 RS08705
gene id: 1136941:ACH46_RS08705
uniprot id: A0A0N9NAT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1136941:ACH46 RS14175
gene id: 1136941:ACH46_RS14175
uniprot id: A0A0N9NCK3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1136941:ACH46 RS12510
gene id: 1136941:ACH46_RS12510
uniprot id: A0A0N9NGR8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1136941:ACH46 RS01355
gene id: 1136941:ACH46_RS01355
uniprot id: A0A0N9MZA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1136941:ACH46 RS15670
gene id: 1136941:ACH46_RS15670
uniprot id: A0A0N7FUY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1136941:ACH46 RS15195
gene id: 1136941:ACH46_RS15195
uniprot id: A0A0N9NJ08
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1136941:ACH46 RS17720
gene id: 1136941:ACH46_RS17720
uniprot id: A0A0N9NC15
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS01665
gene id: 1136941:ACH46_RS01665
uniprot id: A0A0N9N8N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial phospholipase C family.
messages: cell wall

1136941:ACH46 RS04655
gene id: 1136941:ACH46_RS04655
uniprot id: A0A0N9MMG8
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS11735
gene id: 1136941:ACH46_RS11735
uniprot id: A0A0N9N9S9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS07520
gene id: 1136941:ACH46_RS07520
uniprot id: A0A0N9N173
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1136941:ACH46 RS12730
gene id: 1136941:ACH46_RS12730
uniprot id: A0A0N9NC56
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1136941:ACH46 RS16595
gene id: 1136941:ACH46_RS16595
uniprot id: A0A0N9NIT5
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1136941:ACH46 RS07570
gene id: 1136941:ACH46_RS07570
uniprot id: A0A0N9NBJ1
names: Similarity
messages: Belongs to the LppX/LprAFG lipoprotein family.

1136941:ACH46 RS18385
gene id: 1136941:ACH46_RS18385
uniprot id: A0A0N7FV41
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MbtB subfamily.

1136941:ACH46 RS08055
gene id: 1136941:ACH46_RS08055
uniprot id: A0A0N9MNU8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1136941:ACH46 RS15170
gene id: 1136941:ACH46_RS15170
uniprot id: A0A0N9NB05
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1136941:ACH46 RS08130
gene id: 1136941:ACH46_RS08130
uniprot id: A0A0N9MNW9
names: Similarity
messages: Belongs to the FPG family.

1136941:ACH46 RS02880
gene id: 1136941:ACH46_RS02880
uniprot id: A0A0N9N6W7
names: Similarity
messages: Belongs to the CsoR family.

1136941:ACH46 RS03585
gene id: 1136941:ACH46_RS03585
uniprot id: A0A0N7FU98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1136941:ACH46 RS19775
gene id: 1136941:ACH46_RS19775
uniprot id: A0A0N9NGQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1136941:ACH46 RS07150
gene id: 1136941:ACH46_RS07150
uniprot id: A0A0N9NFB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

1136941:ACH46 RS05270
gene id: 1136941:ACH46_RS05270
uniprot id: A0A0N9N7N4
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1136941:ACH46 RS15870
gene id: 1136941:ACH46_RS15870
uniprot id: A0A0N9N5C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

1136941:ACH46 RS04095
gene id: 1136941:ACH46_RS04095
uniprot id: A0A0N9NF10
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1136941:ACH46 RS02940
gene id: 1136941:ACH46_RS02940
uniprot id: A0A0N9MM12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1136941:ACH46 RS07905
gene id: 1136941:ACH46_RS07905
uniprot id: A0A0N9NFL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1136941:ACH46 RS14950
gene id: 1136941:ACH46_RS14950
uniprot id: A0A0N9NI60
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

1136941:ACH46 RS05075
gene id: 1136941:ACH46_RS05075
uniprot id: A0A0N9MMP6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

1136941:ACH46 RS14935
gene id: 1136941:ACH46_RS14935
uniprot id: A0A0N9NCX8
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

1136941:ACH46 RS10110
gene id: 1136941:ACH46_RS10110
uniprot id: A0A0N9N2C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Membrane

1136941:ACH46 RS11915
gene id: 1136941:ACH46_RS11915
uniprot id: A0A0N9NDC0
names: Function
names: Subcellular Location Annotation
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
messages: Membrane

1136941:ACH46 RS12455
gene id: 1136941:ACH46_RS12455
uniprot id: A0A0N9N365
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1136941:ACH46 RS11730
gene id: 1136941:ACH46_RS11730
uniprot id: A0A0N9N3V3
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1136941:ACH46 RS15605
gene id: 1136941:ACH46_RS15605
uniprot id: A0A0N9N4A7
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1136941:ACH46 RS12860
gene id: 1136941:ACH46_RS12860
uniprot id: A0A0N9MRX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

1136941:ACH46 RS05385
gene id: 1136941:ACH46_RS05385
uniprot id: A0A0N9NFI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EccB family.
messages: Membrane

1136941:ACH46 RS20695
gene id: 1136941:ACH46_RS20695
uniprot id: A0A0N9NKD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

1136941:ACH46 RS12285
gene id: 1136941:ACH46_RS12285
uniprot id: A0A0N9N9Z1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS20215
gene id: 1136941:ACH46_RS20215
uniprot id: A0A0N9NK61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1136941:ACH46 RS08125
gene id: 1136941:ACH46_RS08125
uniprot id: A0A0N7FUI7
names: Similarity
messages: Belongs to the LacAB/RpiB family.

1136941:ACH46 RS14300
gene id: 1136941:ACH46_RS14300
uniprot id: A0A0N9NHX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1136941:ACH46 RS10820
gene id: 1136941:ACH46_RS10820
uniprot id: A0A0N9NBC8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

1136941:ACH46 RS02110
gene id: 1136941:ACH46_RS02110
uniprot id: A0A0N9MZG1
names: Subcellular Location Annotation
messages: Cytoplasm

1136941:ACH46 RS08985
gene id: 1136941:ACH46_RS08985
uniprot id: A0A0N9NAP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1136941:ACH46 RS17530
gene id: 1136941:ACH46_RS17530
uniprot id: A0A0N9NFV3
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

1136941:ACH46 RS12950
gene id: 1136941:ACH46_RS12950
uniprot id: A0A0N9NC50
names: Similarity
messages: Belongs to the Dps family.

1136941:ACH46 RS01880
gene id: 1136941:ACH46_RS01880
uniprot id: A0A0N9N911
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

1136941:ACH46 RS07765
gene id: 1136941:ACH46_RS07765
uniprot id: A0A0N9NFJ5
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1136941:ACH46 RS08170
gene id: 1136941:ACH46_RS08170
uniprot id: A0A0N9NAF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1136941:ACH46 RS17235
gene id: 1136941:ACH46_RS17235
uniprot id: A0A0N9NIC6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1136941:ACH46 RS15805
gene id: 1136941:ACH46_RS15805
uniprot id: A0A0N9MRP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1136941:ACH46 RS11335
gene id: 1136941:ACH46_RS11335
uniprot id: A0A0N9NBI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1136941:ACH46 RS20535
gene id: 1136941:ACH46_RS20535
uniprot id: A0A0N9NH21
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1136941:ACH46 RS17290
gene id: 1136941:ACH46_RS17290
uniprot id: A0A0N9N4Z7
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

1136941:ACH46 RS04505
gene id: 1136941:ACH46_RS04505
uniprot id: A0A0N7FUB7
names: Similarity
messages: Belongs to the universal stress protein A family.

1136941:ACH46 RS10180
gene id: 1136941:ACH46_RS10180
uniprot id: A0A0N9MPU2
names: Similarity
messages: Belongs to the thioredoxin family.

1136941:ACH46 RS14910
gene id: 1136941:ACH46_RS14910
uniprot id: A0A0N9MSM5
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1136941:ACH46 RS17585
gene id: 1136941:ACH46_RS17585
uniprot id: A0A0N9MTR3
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

1136941:ACH46 RS02020
gene id: 1136941:ACH46_RS02020
uniprot id: A0A0N9MN61
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS12735
gene id: 1136941:ACH46_RS12735
uniprot id: A0A0N7FUS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

1136941:ACH46 RS13385
gene id: 1136941:ACH46_RS13385
uniprot id: A0A0N7FUT9
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS15300
gene id: 1136941:ACH46_RS15300
uniprot id: A0A0N9NI97
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS18390
gene id: 1136941:ACH46_RS18390
uniprot id: A0A0N9N5H5
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MbtB subfamily.

1136941:ACH46 RS12765
gene id: 1136941:ACH46_RS12765
uniprot id: A0A0N9MRW8
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS17765
gene id: 1136941:ACH46_RS17765
uniprot id: A0A0N9MSE2
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1136941:ACH46 RS04415
gene id: 1136941:ACH46_RS04415
uniprot id: A0A0N9N050
names: Similarity
messages: Belongs to the MmpS family.

1136941:ACH46 RS06600
gene id: 1136941:ACH46_RS06600
uniprot id: A0A0N9NFW8
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1136941:ACH46 RS07660
gene id: 1136941:ACH46_RS07660
uniprot id: A0A0N9MVI5
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

1136941:ACH46 RS12700
gene id: 1136941:ACH46_RS12700
uniprot id: A0A0N9NA38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1136941:ACH46 RS10450
gene id: 1136941:ACH46_RS10450
uniprot id: A0A0N9NHC5
names: Similarity
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Homohexamer. Assembles into a hexameric ring structure.

1136941:ACH46 RS00835
gene id: 1136941:ACH46_RS00835
uniprot id: A0A0N9MLK0
names: Similarity
messages: Belongs to the catalase family.

1136941:ACH46 RS02215
gene id: 1136941:ACH46_RS02215
uniprot id: A0A0N9N0E6
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS15820
gene id: 1136941:ACH46_RS15820
uniprot id: A0A0N9NB94
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1136941:ACH46 RS08970
gene id: 1136941:ACH46_RS08970
uniprot id: A0A0N9MQJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

1136941:ACH46 RS19365
gene id: 1136941:ACH46_RS19365
uniprot id: A0A0N7FV60
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1136941:ACH46 RS09785
gene id: 1136941:ACH46_RS09785
uniprot id: A0A0N9NG82
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1136941:ACH46 RS12115
gene id: 1136941:ACH46_RS12115
uniprot id: A0A0N9NH53
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

1136941:ACH46 RS16140
gene id: 1136941:ACH46_RS16140
uniprot id: A0A0N9N5F9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1136941:ACH46 RS01390
gene id: 1136941:ACH46_RS01390
uniprot id: A0A0N9N025
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1136941:ACH46 RS04805
gene id: 1136941:ACH46_RS04805
uniprot id: A0A0N9MMI5
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS15800
gene id: 1136941:ACH46_RS15800
uniprot id: A0A0N7FUY7
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1136941:ACH46 RS15555
gene id: 1136941:ACH46_RS15555
uniprot id: A0A0N9MRL9
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS07095
gene id: 1136941:ACH46_RS07095
uniprot id: A0A0N9NFA7
names: Similarity
messages: Belongs to the AHA1 family.

1136941:ACH46 RS02485
gene id: 1136941:ACH46_RS02485
uniprot id: A0A0N9N0I1
names: Similarity
messages: Belongs to the alkaline phosphatase family.

1136941:ACH46 RS15665
gene id: 1136941:ACH46_RS15665
uniprot id: A0A0N9NEU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1136941:ACH46 RS19295
gene id: 1136941:ACH46_RS19295
uniprot id: A0A0N9MSZ3
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS16820
gene id: 1136941:ACH46_RS16820
uniprot id: A0A0N9NBP2
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

1136941:ACH46 RS00825
gene id: 1136941:ACH46_RS00825
uniprot id: A0A0N9MZ50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1136941:ACH46 RS14900
gene id: 1136941:ACH46_RS14900
uniprot id: A0A0N9NAW8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

1136941:ACH46 RS04635
gene id: 1136941:ACH46_RS04635
uniprot id: A0A0N9N979
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1136941:ACH46 RS05885
gene id: 1136941:ACH46_RS05885
uniprot id: A0A0N9NFP5
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1136941:ACH46 RS11205
gene id: 1136941:ACH46_RS11205
uniprot id: A0A0N9MQ59
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS06700
gene id: 1136941:ACH46_RS06700
uniprot id: A0A0N9N0X3
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

1136941:ACH46 RS09880
gene id: 1136941:ACH46_RS09880
uniprot id: A0A0N9N360
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS12210
gene id: 1136941:ACH46_RS12210
uniprot id: A0A0N9N7D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1136941:ACH46 RS08460
gene id: 1136941:ACH46_RS08460
uniprot id: A0A0N7FUJ4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1136941:ACH46 RS16300
gene id: 1136941:ACH46_RS16300
uniprot id: A0A0N9MT83
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS08965
gene id: 1136941:ACH46_RS08965
uniprot id: A0A0N9N8V1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1136941:ACH46 RS07400
gene id: 1136941:ACH46_RS07400
uniprot id: A0A0N9NG22
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS09600
gene id: 1136941:ACH46_RS09600
uniprot id: A0A0N9NG68
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1136941:ACH46 RS18905
gene id: 1136941:ACH46_RS18905
uniprot id: A0A0N9N5P9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1136941:ACH46 RS10595
gene id: 1136941:ACH46_RS10595
uniprot id: A0A0N9N2K2
names: Similarity
messages: Belongs to the Fur family.

1136941:ACH46 RS06595
gene id: 1136941:ACH46_RS06595
uniprot id: A0A0N7FUF8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS15430
gene id: 1136941:ACH46_RS15430
uniprot id: A0A0N9NIB6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1136941:ACH46 RS02850
gene id: 1136941:ACH46_RS02850
uniprot id: A0A0N9MZM2
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS04140
gene id: 1136941:ACH46_RS04140
uniprot id: A0A0N9MNZ1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1136941:ACH46 RS11675
gene id: 1136941:ACH46_RS11675
uniprot id: A0A0N9NL89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

1136941:ACH46 RS14005
gene id: 1136941:ACH46_RS14005
uniprot id: A0A0N9N7H7
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1136941:ACH46 RS11400
gene id: 1136941:ACH46_RS11400
uniprot id: A0A0N9NGM3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS12065
gene id: 1136941:ACH46_RS12065
uniprot id: A0A0N9NHX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1136941:ACH46 RS02795
gene id: 1136941:ACH46_RS02795
uniprot id: A0A0N9N0M8
names: Similarity
names: Subunit
messages: Belongs to the multicopper oxidase family.
messages: Homotrimer.

1136941:ACH46 RS06250
gene id: 1136941:ACH46_RS06250
uniprot id: A0A0N7FUF1
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS14875
gene id: 1136941:ACH46_RS14875
uniprot id: A0A0N9N3Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1136941:ACH46 RS02860
gene id: 1136941:ACH46_RS02860
uniprot id: A0A0N9MM10
names: Similarity
messages: Belongs to the GARS family.

1136941:ACH46 RS17215
gene id: 1136941:ACH46_RS17215
uniprot id: A0A0N9N4Z0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

1136941:ACH46 RS20195
gene id: 1136941:ACH46_RS20195
uniprot id: A0A0N9NFD3
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

1136941:ACH46 RS05345
gene id: 1136941:ACH46_RS05345
uniprot id: A0A0N9N1N9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS15290
gene id: 1136941:ACH46_RS15290
uniprot id: A0A0N7FUX7
names: Caution
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1136941:ACH46 RS05410
gene id: 1136941:ACH46_RS05410
uniprot id: A0A0N9MMV3
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1136941:ACH46 RS19845
gene id: 1136941:ACH46_RS19845
uniprot id: A0A0N9MWH0
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

1136941:ACH46 RS01245
gene id: 1136941:ACH46_RS01245
uniprot id: A0A0N9ND14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PhyH family. EctD subfamily.
messages: Homodimer.
messages: Involved in the biosynthesis of 5-hydroxyectoine, called compatible solute, which helps organisms to survive extreme osmotic stress by acting as a highly soluble organic osmolyte. Catalyzes the 2-oxoglutarate-dependent selective hydroxylation of L-ectoine to yield (4S,5S)-5-hydroxyectoine.

1136941:ACH46 RS10020
gene id: 1136941:ACH46_RS10020
uniprot id: A0A0N9MQV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

1136941:ACH46 RS03605
gene id: 1136941:ACH46_RS03605
uniprot id: A0A0N9MM68
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

1136941:ACH46 RS20255
gene id: 1136941:ACH46_RS20255
uniprot id: A0A0N9N677
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

1136941:ACH46 RS19975
gene id: 1136941:ACH46_RS19975
uniprot id: A0A0N9NGU1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1136941:ACH46 RS16945
gene id: 1136941:ACH46_RS16945
uniprot id: A0A0N7FV11
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS07405
gene id: 1136941:ACH46_RS07405
uniprot id: A0A0N9NLN5
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1136941:ACH46 RS16095
gene id: 1136941:ACH46_RS16095
uniprot id: A0A0N9NDG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

1136941:ACH46 RS00750
gene id: 1136941:ACH46_RS00750
uniprot id: A0A0N9MZ33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1136941:ACH46 RS18940
gene id: 1136941:ACH46_RS18940
uniprot id: A0A0N7FV52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1136941:ACH46 RS05905
gene id: 1136941:ACH46_RS05905
uniprot id: A0A0N9N0M0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1136941:ACH46 RS15310
gene id: 1136941:ACH46_RS15310
uniprot id: A0A0N9NB23
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS11195
gene id: 1136941:ACH46_RS11195
uniprot id: A0A0N9N2T2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1136941:ACH46 RS07345
gene id: 1136941:ACH46_RS07345
uniprot id: A0A0N9NBF6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1136941:ACH46 RS07475
gene id: 1136941:ACH46_RS07475
uniprot id: A0A0N9NFG1
names: Similarity
messages: Belongs to the YciI family.

1136941:ACH46 RS11705
gene id: 1136941:ACH46_RS11705
uniprot id: A0A0N9NBS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1136941:ACH46 RS19350
gene id: 1136941:ACH46_RS19350
uniprot id: A0A0N9N5V4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1136941:ACH46 RS04660
gene id: 1136941:ACH46_RS04660
uniprot id: A0A0N7FUC0
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1136941:ACH46 RS02070
gene id: 1136941:ACH46_RS02070
uniprot id: A0A0N9N0C6
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS02280
gene id: 1136941:ACH46_RS02280
uniprot id: A0A0N9NDD7
names: Similarity
messages: Belongs to the group II decarboxylase family.

1136941:ACH46 RS07875
gene id: 1136941:ACH46_RS07875
uniprot id: A0A0N9NGF2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1136941:ACH46 RS14930
gene id: 1136941:ACH46_RS14930
uniprot id: A0A0N9N400
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1136941:ACH46 RS04525
gene id: 1136941:ACH46_RS04525
uniprot id: A0A0N9N1B5
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS19610
gene id: 1136941:ACH46_RS19610
uniprot id: A0A0N9NCT0
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

1136941:ACH46 RS15035
gene id: 1136941:ACH46_RS15035
uniprot id: A0A0N9NAY6
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1136941:ACH46 RS00300
gene id: 1136941:ACH46_RS00300
uniprot id: A0A0N9N8I5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1136941:ACH46 RS05300
gene id: 1136941:ACH46_RS05300
uniprot id: A0A0N9NFH5
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1136941:ACH46 RS08175
gene id: 1136941:ACH46_RS08175
uniprot id: A0A0N7FUI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1136941:ACH46 RS07120
gene id: 1136941:ACH46_RS07120
uniprot id: A0A0N9NA29
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

1136941:ACH46 RS14895
gene id: 1136941:ACH46_RS14895
uniprot id: A0A0N9N4Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1136941:ACH46 RS16280
gene id: 1136941:ACH46_RS16280
uniprot id: A0A0N9MRU1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1136941:ACH46 RS02380
gene id: 1136941:ACH46_RS02380
uniprot id: A0A0N9NE93
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1136941:ACH46 RS09795
gene id: 1136941:ACH46_RS09795
uniprot id: A0A0N7FUM0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

1136941:ACH46 RS17970
gene id: 1136941:ACH46_RS17970
uniprot id: A0A0N9NC58
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1136941:ACH46 RS05480
gene id: 1136941:ACH46_RS05480
uniprot id: A0A0N9NFW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1136941:ACH46 RS15915
gene id: 1136941:ACH46_RS15915
uniprot id: A0A0N9NDB8
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1136941:ACH46 RS20665
gene id: 1136941:ACH46_RS20665
uniprot id: A0A0N9NFH8
names: Similarity
messages: Belongs to the ParB family.

1136941:ACH46 RS17625
gene id: 1136941:ACH46_RS17625
uniprot id: A0A0N9NJ67
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1136941:ACH46 RS11850
gene id: 1136941:ACH46_RS11850
uniprot id: A0A0N9NBP9
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

1136941:ACH46 RS17985
gene id: 1136941:ACH46_RS17985
uniprot id: A0A0N9NG13
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

1136941:ACH46 RS04315
gene id: 1136941:ACH46_RS04315
uniprot id: A0A0N7FUB3
names: Similarity
messages: Belongs to the peptidase S1C family.

1136941:ACH46 RS20345
gene id: 1136941:ACH46_RS20345
uniprot id: A0A0N7FV80
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1136941:ACH46 RS16590
gene id: 1136941:ACH46_RS16590
uniprot id: A0A0N9MRY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1136941:ACH46 RS11625
gene id: 1136941:ACH46_RS11625
uniprot id: A0A0N9NBS1
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

1136941:ACH46 RS02755
gene id: 1136941:ACH46_RS02755
uniprot id: A0A0N9MTR8
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

1136941:ACH46 RS06525
gene id: 1136941:ACH46_RS06525
uniprot id: A0A0N9N9V1
names: Similarity
messages: Belongs to the peptidase C40 family.

1136941:ACH46 RS03600
gene id: 1136941:ACH46_RS03600
uniprot id: A0A0N9N999
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1136941:ACH46 RS13130
gene id: 1136941:ACH46_RS13130
uniprot id: A0A0N9NCA4
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS15395
gene id: 1136941:ACH46_RS15395
uniprot id: A0A0N9ND26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1136941:ACH46 RS00905
gene id: 1136941:ACH46_RS00905
uniprot id: A0A0N7FU44
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M.tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins). In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides.
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer.
messages: In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.
messages: In the N-terminal section; belongs to the LPG synthetase family.
messages: Membrane

1136941:ACH46 RS02765
gene id: 1136941:ACH46_RS02765
uniprot id: A0A0N9MLZ2
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

1136941:ACH46 RS19680
gene id: 1136941:ACH46_RS19680
uniprot id: A0A0N9N6U2
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

1136941:ACH46 RS10460
gene id: 1136941:ACH46_RS10460
uniprot id: A0A0N7FUN4
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup deamidase subfamily.

1136941:ACH46 RS08505
gene id: 1136941:ACH46_RS08505
uniprot id: A0A0N9NE42
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1136941:ACH46 RS07630
gene id: 1136941:ACH46_RS07630
uniprot id: A0A0N9N2F8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1136941:ACH46 RS01955
gene id: 1136941:ACH46_RS01955
uniprot id: A0A0N9MN51
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1136941:ACH46 RS02950
gene id: 1136941:ACH46_RS02950
uniprot id: A0A0N9N0P1
names: Similarity
messages: Belongs to the peptidase M18 family.

1136941:ACH46 RS02705
gene id: 1136941:ACH46_RS02705
uniprot id: A0A0N9N6V3
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1136941:ACH46 RS03990
gene id: 1136941:ACH46_RS03990
uniprot id: A0A0N9NFW6
names: Subcellular Location Annotation
messages: Cell membrane

1136941:ACH46 RS06850
gene id: 1136941:ACH46_RS06850
uniprot id: A0A0N9MND4
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

1136941:ACH46 RS18100
gene id: 1136941:ACH46_RS18100
uniprot id: A0A0N7FV36
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1136941:ACH46 RS01555
gene id: 1136941:ACH46_RS01555
uniprot id: A0A0N9MV38
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1136941:ACH46 RS16975
gene id: 1136941:ACH46_RS16975
uniprot id: A0A0N9NBR2
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS07315
gene id: 1136941:ACH46_RS07315
uniprot id: A0A0N9NFE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

1136941:ACH46 RS14760
gene id: 1136941:ACH46_RS14760
uniprot id: A0A0N9N4W6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1136941:ACH46 RS04185
gene id: 1136941:ACH46_RS04185
uniprot id: A0A0N9NE63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1136941:ACH46 RS11210
gene id: 1136941:ACH46_RS11210
uniprot id: A0A0N9NGU7
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS08570
gene id: 1136941:ACH46_RS08570
uniprot id: A0A0N9MVK1
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

1136941:ACH46 RS07535
gene id: 1136941:ACH46_RS07535
uniprot id: A0A0N9MNL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

1136941:ACH46 RS09995
gene id: 1136941:ACH46_RS09995
uniprot id: A0A0N9MPN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

1136941:ACH46 RS02925
gene id: 1136941:ACH46_RS02925
uniprot id: A0A0N9MZN1
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS11470
gene id: 1136941:ACH46_RS11470
uniprot id: A0A0N9NGX4
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS09900
gene id: 1136941:ACH46_RS09900
uniprot id: A0A0N7FUM2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1136941:ACH46 RS15835
gene id: 1136941:ACH46_RS15835
uniprot id: A0A0N9NDC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1136941:ACH46 RS06190
gene id: 1136941:ACH46_RS06190
uniprot id: A0A0N9MN67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1136941:ACH46 RS01285
gene id: 1136941:ACH46_RS01285
uniprot id: A0A0N9MZ97
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

1136941:ACH46 RS15455
gene id: 1136941:ACH46_RS15455
uniprot id: A0A0N9ND36
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1136941:ACH46 RS09870
gene id: 1136941:ACH46_RS09870
uniprot id: A0A0N9MPM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1136941:ACH46 RS07885
gene id: 1136941:ACH46_RS07885
uniprot id: A0A0N9N1E7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

1136941:ACH46 RS06790
gene id: 1136941:ACH46_RS06790
uniprot id: A0A0N9NF62
names: Similarity
messages: Belongs to the AccD/PCCB family.

1136941:ACH46 RS01450
gene id: 1136941:ACH46_RS01450
uniprot id: A0A0N9ND42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1136941:ACH46 RS07440
gene id: 1136941:ACH46_RS07440
uniprot id: A0A0N7FUH4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1136941:ACH46 RS09430
gene id: 1136941:ACH46_RS09430
uniprot id: A0A0N9N920
names: Similarity
messages: Belongs to the peptidase S51 family.

1136941:ACH46 RS15770
gene id: 1136941:ACH46_RS15770
uniprot id: A0A0N9NEV9
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family. MbtB subfamily.

1136941:ACH46 RS03320
gene id: 1136941:ACH46_RS03320
uniprot id: A0A0N9MZR6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1136941:ACH46 RS13715
gene id: 1136941:ACH46_RS13715
uniprot id: A0A0N9NGU8
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS02430
gene id: 1136941:ACH46_RS02430
uniprot id: A0A0N9N9A1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1136941:ACH46 RS16170
gene id: 1136941:ACH46_RS16170
uniprot id: A0A0N7FUZ5
names: Similarity
messages: Belongs to the CFA/CMAS family.

1136941:ACH46 RS07225
gene id: 1136941:ACH46_RS07225
uniprot id: A0A0N7FUH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1136941:ACH46 RS10130
gene id: 1136941:ACH46_RS10130
uniprot id: A0A0N9NGD9
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1136941:ACH46 RS09915
gene id: 1136941:ACH46_RS09915
uniprot id: A0A0N9NH59
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1136941:ACH46 RS19120
gene id: 1136941:ACH46_RS19120
uniprot id: A0A0N9MUZ9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1136941:ACH46 RS12945
gene id: 1136941:ACH46_RS12945
uniprot id: A0A0N9NDR0
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1136941:ACH46 RS10235
gene id: 1136941:ACH46_RS10235
uniprot id: A0A0N9NHA1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

1136941:ACH46 RS12815
gene id: 1136941:ACH46_RS12815
uniprot id: A0A0N9NC63
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS04100
gene id: 1136941:ACH46_RS04100
uniprot id: A0A0N9N010
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1136941:ACH46 RS13770
gene id: 1136941:ACH46_RS13770
uniprot id: A0A0N9MR21
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

1136941:ACH46 RS15830
gene id: 1136941:ACH46_RS15830
uniprot id: A0A0N9NEW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

1136941:ACH46 RS11075
gene id: 1136941:ACH46_RS11075
uniprot id: A0A0N9NGS7
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

1136941:ACH46 RS11405
gene id: 1136941:ACH46_RS11405
uniprot id: A0A0N7FUQ2
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

1136941:ACH46 RS08510
gene id: 1136941:ACH46_RS08510
uniprot id: A0A0N9MQD1
names: Similarity
messages: Belongs to the DprA/Smf family.

1136941:ACH46 RS02255
gene id: 1136941:ACH46_RS02255
uniprot id: A0A0N7FU71
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1136941:ACH46 RS05595
gene id: 1136941:ACH46_RS05595
uniprot id: A0A0N9N7R4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1136941:ACH46 RS14140
gene id: 1136941:ACH46_RS14140
uniprot id: A0A0N9NHV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1136941:ACH46 RS09590
gene id: 1136941:ACH46_RS09590
uniprot id: A0A0N9NB33
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS07790
gene id: 1136941:ACH46_RS07790
uniprot id: A0A0N9NAA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1136941:ACH46 RS16215
gene id: 1136941:ACH46_RS16215
uniprot id: A0A0N9N5G7
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

1136941:ACH46 RS10420
gene id: 1136941:ACH46_RS10420
uniprot id: A0A0N9N3E2
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1136941:ACH46 RS19840
gene id: 1136941:ACH46_RS19840
uniprot id: A0A0N9MUN2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1136941:ACH46 RS10780
gene id: 1136941:ACH46_RS10780
uniprot id: A0A0N7FUP0
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1136941:ACH46 RS10300
gene id: 1136941:ACH46_RS10300
uniprot id: A0A0N9NHB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

1136941:ACH46 RS16210
gene id: 1136941:ACH46_RS16210
uniprot id: A0A0N9NIM7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1136941:ACH46 RS03460
gene id: 1136941:ACH46_RS03460
uniprot id: A0A0N9NEP6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1136941:ACH46 RS07720
gene id: 1136941:ACH46_RS07720
uniprot id: A0A0N9NHN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1136941:ACH46 RS09035
gene id: 1136941:ACH46_RS09035
uniprot id: A0A0N9NC45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1136941:ACH46 RS07220
gene id: 1136941:ACH46_RS07220
uniprot id: A0A0N9MNH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1136941:ACH46 RS08715
gene id: 1136941:ACH46_RS08715
uniprot id: A0A0N9NFW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1136941:ACH46 RS06050
gene id: 1136941:ACH46_RS06050
uniprot id: A0A0N9N0N4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1136941:ACH46 RS09775
gene id: 1136941:ACH46_RS09775
uniprot id: A0A0N9NB58
names: Similarity
messages: Belongs to the peptidase A24 family.

1136941:ACH46 RS12760
gene id: 1136941:ACH46_RS12760
uniprot id: A0A0N9NA47
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

1136941:ACH46 RS06150
gene id: 1136941:ACH46_RS06150
uniprot id: A0A0N9N7X7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1136941:ACH46 RS09905
gene id: 1136941:ACH46_RS09905
uniprot id: A0A0N9NL41
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1136941:ACH46 RS10305
gene id: 1136941:ACH46_RS10305
uniprot id: A0A0N7FUN1
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

1136941:ACH46 RS09000
gene id: 1136941:ACH46_RS09000
uniprot id: A0A0N7FUK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1136941:ACH46 RS06860
gene id: 1136941:ACH46_RS06860
uniprot id: A0A0N9N7N9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1136941:ACH46 RS10950
gene id: 1136941:ACH46_RS10950
uniprot id: A0A0N7FUP3
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

1136941:ACH46 RS20605
gene id: 1136941:ACH46_RS20605
uniprot id: A0A0N9NFG7
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS03390
gene id: 1136941:ACH46_RS03390
uniprot id: A0A0N9N977
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbxX/CfxQ family.
messages: Cytoplasm

1136941:ACH46 RS20645
gene id: 1136941:ACH46_RS20645
uniprot id: A0A0N7FV86
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1136941:ACH46 RS00380
gene id: 1136941:ACH46_RS00380
uniprot id: A0A0N7FU34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diaminopimelate dehydrogenase family.
messages: Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.
messages: Homodimer.

1136941:ACH46 RS00875
gene id: 1136941:ACH46_RS00875
uniprot id: A0A0N9NDT6
names: Similarity
messages: Belongs to the glutamate synthase family.

1136941:ACH46 RS16225
gene id: 1136941:ACH46_RS16225
uniprot id: A0A0N7FUZ6
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1136941:ACH46 RS18035
gene id: 1136941:ACH46_RS18035
uniprot id: A0A0N9N675
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

1136941:ACH46 RS01240
gene id: 1136941:ACH46_RS01240
uniprot id: A0A0N9MLM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arabinosyl transferase responsible for the polymerization of arabinose into the arabinan of arabinogalactan.
messages: Belongs to the emb family.
messages: Cell membrane
messages: Membrane

1136941:ACH46 RS07835
gene id: 1136941:ACH46_RS07835
uniprot id: A0A0N9N8G7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1136941:ACH46 RS17380
gene id: 1136941:ACH46_RS17380
uniprot id: A0A0N7FV20
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

1136941:ACH46 RS01795
gene id: 1136941:ACH46_RS01795
uniprot id: A0A0N9NKG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1136941:ACH46 RS01000
gene id: 1136941:ACH46_RS01000
uniprot id: A0A0N9N6E3
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

1136941:ACH46 RS03245
gene id: 1136941:ACH46_RS03245
uniprot id: A0A0N9NEL1
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family.

1136941:ACH46 RS01040
gene id: 1136941:ACH46_RS01040
uniprot id: A0A0N9MLL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1136941:ACH46 RS07635
gene id: 1136941:ACH46_RS07635
uniprot id: A0A0N9N8E0
names: Similarity
messages: Belongs to the group II decarboxylase family.

1136941:ACH46 RS15330
gene id: 1136941:ACH46_RS15330
uniprot id: A0A0N7FUX8
names: Similarity
messages: Belongs to the WXG100 family.

1136941:ACH46 RS07335
gene id: 1136941:ACH46_RS07335
uniprot id: A0A0N7FUH2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1136941:ACH46 RS09030
gene id: 1136941:ACH46_RS09030
uniprot id: A0A0N9MQJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1136941:ACH46 RS09150
gene id: 1136941:ACH46_RS09150
uniprot id: A0A0N9MPB0
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1136941:ACH46 RS05975
gene id: 1136941:ACH46_RS05975
uniprot id: A0A0N9MVC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1136941:ACH46 RS02990
gene id: 1136941:ACH46_RS02990
uniprot id: A0A0N9N8P5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1136941:ACH46 RS20675
gene id: 1136941:ACH46_RS20675
uniprot id: A0A0N9N6D4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

1136941:ACH46 RS06915
gene id: 1136941:ACH46_RS06915
uniprot id: A0A0N9NG27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1136941:ACH46 RS04390
gene id: 1136941:ACH46_RS04390
uniprot id: A0A0N9MP24
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1136941:ACH46 RS13585
gene id: 1136941:ACH46_RS13585
uniprot id: A0A0N9NAF0
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS16725
gene id: 1136941:ACH46_RS16725
uniprot id: A0A0N9N4S3
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Could possibly oxidize fatty acids using specific components.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS15810
gene id: 1136941:ACH46_RS15810
uniprot id: A0A0N9NIG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1136941:ACH46 RS13100
gene id: 1136941:ACH46_RS13100
uniprot id: A0A0N9NDU0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1136941:ACH46 RS04925
gene id: 1136941:ACH46_RS04925
uniprot id: A0A0N9N9B5
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1136941:ACH46 RS14925
gene id: 1136941:ACH46_RS14925
uniprot id: A0A0N9NIX7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1136941:ACH46 RS01875
gene id: 1136941:ACH46_RS01875
uniprot id: A0A0N9MN41
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1136941:ACH46 RS17305
gene id: 1136941:ACH46_RS17305
uniprot id: A0A0N9MS57
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1136941:ACH46 RS08665
gene id: 1136941:ACH46_RS08665
uniprot id: A0A0N9NC04
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1136941:ACH46 RS08025
gene id: 1136941:ACH46_RS08025
uniprot id: A0A0N9NAD2
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

1136941:ACH46 RS15815
gene id: 1136941:ACH46_RS15815
uniprot id: A0A0N9N5B1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1136941:ACH46 RS02365
gene id: 1136941:ACH46_RS02365
uniprot id: A0A0N9N990
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1136941:ACH46 RS10770
gene id: 1136941:ACH46_RS10770
uniprot id: A0A0N9MQ08
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

1136941:ACH46 RS06330
gene id: 1136941:ACH46_RS06330
uniprot id: A0A0N9N0S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

1136941:ACH46 RS20230
gene id: 1136941:ACH46_RS20230
uniprot id: A0A0N9MUU0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1136941:ACH46 RS17400
gene id: 1136941:ACH46_RS17400
uniprot id: A0A0N7FVF3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1136941:ACH46 RS04065
gene id: 1136941:ACH46_RS04065
uniprot id: A0A0N9N784
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1136941:ACH46 RS12580
gene id: 1136941:ACH46_RS12580
uniprot id: A0A0N9NBZ7
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.
messages: Homodimer.

1136941:ACH46 RS09985
gene id: 1136941:ACH46_RS09985
uniprot id: A0A0N9NB81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1136941:ACH46 RS07695
gene id: 1136941:ACH46_RS07695
uniprot id: A0A0N9N2G2
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS16970
gene id: 1136941:ACH46_RS16970
uniprot id: A0A0N9N5S5
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS07880
gene id: 1136941:ACH46_RS07880
uniprot id: A0A0N9N705
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1136941:ACH46 RS07245
gene id: 1136941:ACH46_RS07245
uniprot id: A0A0N9MPZ7
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1136941:ACH46 RS11260
gene id: 1136941:ACH46_RS11260
uniprot id: A0A0N9NL75
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family.

1136941:ACH46 RS12450
gene id: 1136941:ACH46_RS12450
uniprot id: A0A0N7FUS1
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1136941:ACH46 RS17260
gene id: 1136941:ACH46_RS17260
uniprot id: A0A0N9NFR5
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1136941:ACH46 RS19820
gene id: 1136941:ACH46_RS19820
uniprot id: A0A0N9NK02
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1136941:ACH46 RS07435
gene id: 1136941:ACH46_RS07435
uniprot id: A0A0N9N162
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1136941:ACH46 RS10140
gene id: 1136941:ACH46_RS10140
uniprot id: A0A0N9N9A3
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1136941:ACH46 RS08560
gene id: 1136941:ACH46_RS08560
uniprot id: A0A0N9N2R0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1136941:ACH46 RS15845
gene id: 1136941:ACH46_RS15845
uniprot id: A0A0N9NJ86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1136941:ACH46 RS07665
gene id: 1136941:ACH46_RS07665
uniprot id: A0A0N7FUH8
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

1136941:ACH46 RS07190
gene id: 1136941:ACH46_RS07190
uniprot id: A0A0N9NA40
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS17240
gene id: 1136941:ACH46_RS17240
uniprot id: A0A0N9NJ11
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS16670
gene id: 1136941:ACH46_RS16670
uniprot id: A0A0N9NIU3
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

1136941:ACH46 RS20400
gene id: 1136941:ACH46_RS20400
uniprot id: A0A0N9N8P4
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

1136941:ACH46 RS11670
gene id: 1136941:ACH46_RS11670
uniprot id: A0A0N9MUE5
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1136941:ACH46 RS04785
gene id: 1136941:ACH46_RS04785
uniprot id: A0A0N9N995
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1136941:ACH46 RS15120
gene id: 1136941:ACH46_RS15120
uniprot id: A0A0N9NCY6
names: Similarity
messages: Belongs to the DEAD box helicase family.

1136941:ACH46 RS17965
gene id: 1136941:ACH46_RS17965
uniprot id: A0A0N9N657
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

1136941:ACH46 RS03475
gene id: 1136941:ACH46_RS03475
uniprot id: A0A0N9MM62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1136941:ACH46 RS12440
gene id: 1136941:ACH46_RS12440
uniprot id: A0A0N9NBX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

1136941:ACH46 RS11510
gene id: 1136941:ACH46_RS11510
uniprot id: A0A0N9ND60
names: Similarity
messages: Belongs to the AHA1 family.

1136941:ACH46 RS08590
gene id: 1136941:ACH46_RS08590
uniprot id: A0A0N9NC00
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1136941:ACH46 RS12770
gene id: 1136941:ACH46_RS12770
uniprot id: A0A0N9NDN0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1136941:ACH46 RS02310
gene id: 1136941:ACH46_RS02310
uniprot id: A0A0N9N980
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1136941:ACH46 RS19545
gene id: 1136941:ACH46_RS19545
uniprot id: A0A0N9N6S2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1136941:ACH46 RS09920
gene id: 1136941:ACH46_RS09920
uniprot id: A0A0N9N2A3
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1136941:ACH46 RS17770
gene id: 1136941:ACH46_RS17770
uniprot id: A0A0N9N7R6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1136941:ACH46 RS17930
gene id: 1136941:ACH46_RS17930
uniprot id: A0A0N9NE96
names: Similarity
messages: Belongs to the asp23 family.

1136941:ACH46 RS06675
gene id: 1136941:ACH46_RS06675
uniprot id: A0A0N7FVB2
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

1136941:ACH46 RS09095
gene id: 1136941:ACH46_RS09095
uniprot id: A0A0N7FUK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1136941:ACH46 RS15560
gene id: 1136941:ACH46_RS15560
uniprot id: A0A0N9NID6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

1136941:ACH46 RS12910
gene id: 1136941:ACH46_RS12910
uniprot id: A0A0N7FUT0
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1136941:ACH46 RS10600
gene id: 1136941:ACH46_RS10600
uniprot id: A0A0N9NBF9
names: Caution
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS20225
gene id: 1136941:ACH46_RS20225
uniprot id: A0A0N9ND29
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1136941:ACH46 RS02620
gene id: 1136941:ACH46_RS02620
uniprot id: A0A0N9N0L1
names: Cofactor
messages: Can also use Mn(2+) ion.

1136941:ACH46 RS03955
gene id: 1136941:ACH46_RS03955
uniprot id: A0A0N9N903
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1136941:ACH46 RS02495
gene id: 1136941:ACH46_RS02495
uniprot id: A0A0N9N6T2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

1136941:ACH46 RS16265
gene id: 1136941:ACH46_RS16265
uniprot id: A0A0N9N4L2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1136941:ACH46 RS08585
gene id: 1136941:ACH46_RS08585
uniprot id: A0A0N9MQE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1136941:ACH46 RS15410
gene id: 1136941:ACH46_RS15410
uniprot id: A0A0N9ND49
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

1136941:ACH46 RS03520
gene id: 1136941:ACH46_RS03520
uniprot id: A0A0N9N992
names: Similarity
messages: Belongs to the TmoD/XamoD family.

1136941:ACH46 RS09375
gene id: 1136941:ACH46_RS09375
uniprot id: A0A0N7FUL2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1136941:ACH46 RS11830
gene id: 1136941:ACH46_RS11830
uniprot id: A0A0N7FUQ9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1136941:ACH46 RS08500
gene id: 1136941:ACH46_RS08500
uniprot id: A0A0N9N7R7
names: Similarity
messages: Belongs to the UPF0102 family.

1136941:ACH46 RS17030
gene id: 1136941:ACH46_RS17030
uniprot id: A0A0N9NIY1
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1136941:ACH46 RS12260
gene id: 1136941:ACH46_RS12260
uniprot id: A0A0N9NH70
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1136941:ACH46 RS07210
gene id: 1136941:ACH46_RS07210
uniprot id: A0A0N9N139
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1136941:ACH46 RS07930
gene id: 1136941:ACH46_RS07930
uniprot id: A0A0N9MQ62
names: Similarity
messages: Belongs to the YciI family.

1136941:ACH46 RS01460
gene id: 1136941:ACH46_RS01460
uniprot id: A0A0N7FU56
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1136941:ACH46 RS00385
gene id: 1136941:ACH46_RS00385
uniprot id: A0A0N9NL57
names: Similarity
messages: Belongs to the universal stress protein A family.

1136941:ACH46 RS06430
gene id: 1136941:ACH46_RS06430
uniprot id: A0A0N9NFZ1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1136941:ACH46 RS13745
gene id: 1136941:ACH46_RS13745
uniprot id: A0A0N9MUK5
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1136941:ACH46 RS05730
gene id: 1136941:ACH46_RS05730
uniprot id: A0A0N9NAQ9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1136941:ACH46 RS02945
gene id: 1136941:ACH46_RS02945
uniprot id: A0A0N9NDL8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

1136941:ACH46 RS08245
gene id: 1136941:ACH46_RS08245
uniprot id: A0A0N9NG42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1136941:ACH46 RS04375
gene id: 1136941:ACH46_RS04375
uniprot id: A0A0N9NE92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

1136941:ACH46 RS18735
gene id: 1136941:ACH46_RS18735
uniprot id: A0A0N9NEL6
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

1136941:ACH46 RS10030
gene id: 1136941:ACH46_RS10030
uniprot id: A0A0N9NCI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

1136941:ACH46 RS06670
gene id: 1136941:ACH46_RS06670
uniprot id: A0A0N9NB62
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1136941:ACH46 RS03810
gene id: 1136941:ACH46_RS03810
uniprot id: A0A0N9N8Y8
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

1136941:ACH46 RS08685
gene id: 1136941:ACH46_RS08685
uniprot id: A0A0N7FVC0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1136941:ACH46 RS13705
gene id: 1136941:ACH46_RS13705
uniprot id: A0A0N9NHQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1136941:ACH46 RS15910
gene id: 1136941:ACH46_RS15910
uniprot id: A0A0N9N4G3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1136941:ACH46 RS10765
gene id: 1136941:ACH46_RS10765
uniprot id: A0A0N9NBH5
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

1136941:ACH46 RS00290
gene id: 1136941:ACH46_RS00290
uniprot id: A0A0N7FU32
names: Similarity
messages: Belongs to the TfdA dioxygenase family.

1136941:ACH46 RS11965
gene id: 1136941:ACH46_RS11965
uniprot id: A0A0N9MRK3
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.

1136941:ACH46 RS04985
gene id: 1136941:ACH46_RS04985
uniprot id: A0A0N7FVA4
names: Similarity
messages: Belongs to the pirin family.

1136941:ACH46 RS12470
gene id: 1136941:ACH46_RS12470
uniprot id: A0A0N9NH98
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS14960
gene id: 1136941:ACH46_RS14960
uniprot id: A0A0N9NAX4
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

1136941:ACH46 RS01310
gene id: 1136941:ACH46_RS01310
uniprot id: A0A0N9ND23
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1136941:ACH46 RS17410
gene id: 1136941:ACH46_RS17410
uniprot id: A0A0N9NFT3
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

1136941:ACH46 RS08320
gene id: 1136941:ACH46_RS08320
uniprot id: A0A0N9MNZ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

1136941:ACH46 RS17230
gene id: 1136941:ACH46_RS17230
uniprot id: A0A0N9MS50
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

1136941:ACH46 RS03270
gene id: 1136941:ACH46_RS03270
uniprot id: A0A0N9MM48
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1136941:ACH46 RS16055
gene id: 1136941:ACH46_RS16055
uniprot id: A0A0N9NDE6
names: Similarity
messages: Belongs to the cytochrome P450 family.

1136941:ACH46 RS09120
gene id: 1136941:ACH46_RS09120
uniprot id: A0A0N9NGW3
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

1136941:ACH46 RS00975
gene id: 1136941:ACH46_RS00975
uniprot id: A0A0N9NCY1
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS11800
gene id: 1136941:ACH46_RS11800
uniprot id: A0A0N9MQD0
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1136941:ACH46 RS02410
gene id: 1136941:ACH46_RS02410
uniprot id: A0A0N9NDF6
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1136941:ACH46 RS19530
gene id: 1136941:ACH46_RS19530
uniprot id: A0A0N7FV63
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS03830
gene id: 1136941:ACH46_RS03830
uniprot id: A0A0N9N9C2
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family.

1136941:ACH46 RS05335
gene id: 1136941:ACH46_RS05335
uniprot id: A0A0N9NEN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

1136941:ACH46 RS10985
gene id: 1136941:ACH46_RS10985
uniprot id: A0A0N9N2P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1136941:ACH46 RS06735
gene id: 1136941:ACH46_RS06735
uniprot id: A0A0N9N845
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

1136941:ACH46 RS14880
gene id: 1136941:ACH46_RS14880
uniprot id: A0A0N9NCW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

1136941:ACH46 RS06225
gene id: 1136941:ACH46_RS06225
uniprot id: A0A0N9NKS3
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

1136941:ACH46 RS19755
gene id: 1136941:ACH46_RS19755
uniprot id: A0A0N9NJZ2
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1136941:ACH46 RS15265
gene id: 1136941:ACH46_RS15265
uniprot id: A0A0N9ND07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

1136941:ACH46 RS06715
gene id: 1136941:ACH46_RS06715
uniprot id: A0A0N7FUG0
names: Similarity
messages: Belongs to the citrate synthase family.

1136941:ACH46 RS17040
gene id: 1136941:ACH46_RS17040
uniprot id: A0A0N7FV13
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1136941:ACH46 RS18830
gene id: 1136941:ACH46_RS18830
uniprot id: A0A0N9MST2
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

1136941:ACH46 RS07135
gene id: 1136941:ACH46_RS07135
uniprot id: A0A0N9N134
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1136941:ACH46 RS02175
gene id: 1136941:ACH46_RS02175
uniprot id: A0A0N9N7A8
names: Similarity
messages: Belongs to the AHA1 family.

1136941:ACH46 RS06300
gene id: 1136941:ACH46_RS06300
uniprot id: A0A0N7FUF2
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS08660
gene id: 1136941:ACH46_RS08660
uniprot id: A0A0N9MQE7
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

1136941:ACH46 RS16240
gene id: 1136941:ACH46_RS16240
uniprot id: A0A0N9MT79
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1136941:ACH46 RS09760
gene id: 1136941:ACH46_RS09760
uniprot id: A0A0N9NAY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1136941:ACH46 RS08030
gene id: 1136941:ACH46_RS08030
uniprot id: A0A0N9N7R0
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

1136941:ACH46 RS15885
gene id: 1136941:ACH46_RS15885
uniprot id: A0A0N9MT34
names: Similarity
messages: Belongs to the creatininase superfamily.

1136941:ACH46 RS11795
gene id: 1136941:ACH46_RS11795
uniprot id: A0A0N9NBT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1136941:ACH46 RS07395
gene id: 1136941:ACH46_RS07395
uniprot id: A0A0N9MQ10
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1136941:ACH46 RS06170
gene id: 1136941:ACH46_RS06170
uniprot id: A0A0N9N9Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

1136941:ACH46 RS02560
gene id: 1136941:ACH46_RS02560
uniprot id: A0A0N9N9C4
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS18095
gene id: 1136941:ACH46_RS18095
uniprot id: A0A0N9N684
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

1136941:ACH46 RS08750
gene id: 1136941:ACH46_RS08750
uniprot id: A0A0N9NAL6
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.

1136941:ACH46 RS08300
gene id: 1136941:ACH46_RS08300
uniprot id: A0A0N9NGK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1136941:ACH46 RS08710
gene id: 1136941:ACH46_RS08710
uniprot id: A0A0N9MP49
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1136941:ACH46 RS06475
gene id: 1136941:ACH46_RS06475
uniprot id: A0A0N9N0T9
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

1136941:ACH46 RS12185
gene id: 1136941:ACH46_RS12185
uniprot id: A0A0N9N3Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1136941:ACH46 RS09165
gene id: 1136941:ACH46_RS09165
uniprot id: A0A0N9N8X4
names: Subcellular Location Annotation
messages: Cytoplasm

1136941:ACH46 RS18615
gene id: 1136941:ACH46_RS18615
uniprot id: A0A0N9N5L1
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS15460
gene id: 1136941:ACH46_RS15460
uniprot id: A0A0N9NJ45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1136941:ACH46 RS07795
gene id: 1136941:ACH46_RS07795
uniprot id: A0A0N9NGE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1136941:ACH46 RS12995
gene id: 1136941:ACH46_RS12995
uniprot id: A0A0N9NHH0
names: Similarity
messages: Belongs to the CdaR family.

1136941:ACH46 RS11605
gene id: 1136941:ACH46_RS11605
uniprot id: A0A0N9NBL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

1136941:ACH46 RS00940
gene id: 1136941:ACH46_RS00940
uniprot id: A0A0N9N8Q6
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1136941:ACH46 RS11880
gene id: 1136941:ACH46_RS11880
uniprot id: A0A0N7FUR0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1136941:ACH46 RS00405
gene id: 1136941:ACH46_RS00405
uniprot id: A0A0N9NCQ8
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS00375
gene id: 1136941:ACH46_RS00375
uniprot id: A0A0N9MYY5
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS03045
gene id: 1136941:ACH46_RS03045
uniprot id: A0A0N9MTS7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1136941:ACH46 RS09725
gene id: 1136941:ACH46_RS09725
uniprot id: A0A0N9NG86
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1136941:ACH46 RS10445
gene id: 1136941:ACH46_RS10445
uniprot id: A0A0N9NB82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

1136941:ACH46 RS02045
gene id: 1136941:ACH46_RS02045
uniprot id: A0A0N9N8S8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1136941:ACH46 RS01645
gene id: 1136941:ACH46_RS01645
uniprot id: A0A0N9N8X8
names: Similarity
names: Subunit
messages: Belongs to the muconolactone Delta-isomerase family.
messages: Homodecamer.

1136941:ACH46 RS20000
gene id: 1136941:ACH46_RS20000
uniprot id: A0A0N9MT99
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS12540
gene id: 1136941:ACH46_RS12540
uniprot id: A0A0N9NC23
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1136941:ACH46 RS10370
gene id: 1136941:ACH46_RS10370
uniprot id: A0A0N7FUN2
names: Similarity
messages: Belongs to the UPF0098 family.

1136941:ACH46 RS08205
gene id: 1136941:ACH46_RS08205
uniprot id: A0A0N9N2M5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

1136941:ACH46 RS05820
gene id: 1136941:ACH46_RS05820
uniprot id: A0A0N9NAS0
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

1136941:ACH46 RS17360
gene id: 1136941:ACH46_RS17360
uniprot id: A0A0N9N507
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1136941:ACH46 RS05275
gene id: 1136941:ACH46_RS05275
uniprot id: A0A0N9MPB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

1136941:ACH46 RS06460
gene id: 1136941:ACH46_RS06460
uniprot id: A0A0N7FVB1
names: Similarity
messages: Belongs to the peptidase S11 family.

1136941:ACH46 RS15655
gene id: 1136941:ACH46_RS15655
uniprot id: A0A0N9NB74
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1136941:ACH46 RS15030
gene id: 1136941:ACH46_RS15030
uniprot id: A0A0N9N503
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

1136941:ACH46 RS16995
gene id: 1136941:ACH46_RS16995
uniprot id: A0A0N9NFM6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1136941:ACH46 RS08285
gene id: 1136941:ACH46_RS08285
uniprot id: A0A0N9MQ99
names: Function
names: Similarity
messages: Belongs to the acetyltransferase family. EctA subfamily.
messages: Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.

1136941:ACH46 RS13160
gene id: 1136941:ACH46_RS13160
uniprot id: A0A0N9MS23
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS15780
gene id: 1136941:ACH46_RS15780
uniprot id: A0A0N9NJ79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1136941:ACH46 RS16490
gene id: 1136941:ACH46_RS16490
uniprot id: A0A0N7FV02
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1136941:ACH46 RS02760
gene id: 1136941:ACH46_RS02760
uniprot id: A0A0N9N8Z9
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

1136941:ACH46 RS02415
gene id: 1136941:ACH46_RS02415
uniprot id: A0A0N9N0H1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

1136941:ACH46 RS11475
gene id: 1136941:ACH46_RS11475
uniprot id: A0A0N7FUQ3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1136941:ACH46 RS11245
gene id: 1136941:ACH46_RS11245
uniprot id: A0A0N9NBH7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1136941:ACH46 RS01250
gene id: 1136941:ACH46_RS01250
uniprot id: A0A0N9N004
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1136941:ACH46 RS06285
gene id: 1136941:ACH46_RS06285
uniprot id: A0A0N9N213
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1136941:ACH46 RS20545
gene id: 1136941:ACH46_RS20545
uniprot id: A0A0N9NL26
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS09815
gene id: 1136941:ACH46_RS09815
uniprot id: A0A0N9N962
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1136941:ACH46 RS07710
gene id: 1136941:ACH46_RS07710
uniprot id: A0A0N9MQ38
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1136941:ACH46 RS00025
gene id: 1136941:ACH46_RS00025
uniprot id: A0A0N7FU27
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1136941:ACH46 RS20350
gene id: 1136941:ACH46_RS20350
uniprot id: A0A0N9NK78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

1136941:ACH46 RS17905
gene id: 1136941:ACH46_RS17905
uniprot id: A0A0N9N649
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

1136941:ACH46 RS12905
gene id: 1136941:ACH46_RS12905
uniprot id: A0A0N9MQP3
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1136941:ACH46 RS00635
gene id: 1136941:ACH46_RS00635
uniprot id: A0A0N9MZR5
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

1136941:ACH46 RS11715
gene id: 1136941:ACH46_RS11715
uniprot id: A0A0N9MQB9
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS12220
gene id: 1136941:ACH46_RS12220
uniprot id: A0A0N9NDE7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1136941:ACH46 RS12010
gene id: 1136941:ACH46_RS12010
uniprot id: A0A0N9MQF2
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

1136941:ACH46 RS05225
gene id: 1136941:ACH46_RS05225
uniprot id: A0A0N7FVA5
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1136941:ACH46 RS06090
gene id: 1136941:ACH46_RS06090
uniprot id: A0A0N9NAW5
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS06245
gene id: 1136941:ACH46_RS06245
uniprot id: A0A0N9NFT1
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1136941:ACH46 RS17390
gene id: 1136941:ACH46_RS17390
uniprot id: A0A0N9N5X8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1136941:ACH46 RS09295
gene id: 1136941:ACH46_RS09295
uniprot id: A0A0N9N2Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1136941:ACH46 RS00610
gene id: 1136941:ACH46_RS00610
uniprot id: A0A0N7FV89
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

1136941:ACH46 RS01365
gene id: 1136941:ACH46_RS01365
uniprot id: A0A0N9N8I6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1136941:ACH46 RS06395
gene id: 1136941:ACH46_RS06395
uniprot id: A0A0N7FUF4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS19795
gene id: 1136941:ACH46_RS19795
uniprot id: A0A0N9N8N5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate, the first step in the de novo biosynthesis of NAD(+).
messages: Cytoplasm

1136941:ACH46 RS09825
gene id: 1136941:ACH46_RS09825
uniprot id: A0A0N9NCF3
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

1136941:ACH46 RS08945
gene id: 1136941:ACH46_RS08945
uniprot id: A0A0N9NFY4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.

1136941:ACH46 RS04510
gene id: 1136941:ACH46_RS04510
uniprot id: A0A0N9MME6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

1136941:ACH46 RS17980
gene id: 1136941:ACH46_RS17980
uniprot id: A0A0N9NH56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

1136941:ACH46 RS18005
gene id: 1136941:ACH46_RS18005
uniprot id: A0A0N9N5C1
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS09840
gene id: 1136941:ACH46_RS09840
uniprot id: A0A0N9NH49
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1136941:ACH46 RS05780
gene id: 1136941:ACH46_RS05780
uniprot id: A0A0N9NLI0
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS09040
gene id: 1136941:ACH46_RS09040
uniprot id: A0A0N7FUK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1136941:ACH46 RS14645
gene id: 1136941:ACH46_RS14645
uniprot id: A0A0N7FUW4
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS07140
gene id: 1136941:ACH46_RS07140
uniprot id: A0A0N9NAD0
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1136941:ACH46 RS12480
gene id: 1136941:ACH46_RS12480
uniprot id: A0A0N9N436
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1136941:ACH46 RS05010
gene id: 1136941:ACH46_RS05010
uniprot id: A0A0N7FUC7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1136941:ACH46 RS07975
gene id: 1136941:ACH46_RS07975
uniprot id: A0A0N9NAJ0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1136941:ACH46 RS19470
gene id: 1136941:ACH46_RS19470
uniprot id: A0A0N9N8M2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

1136941:ACH46 RS00305
gene id: 1136941:ACH46_RS00305
uniprot id: A0A0N9N7X8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1136941:ACH46 RS05670
gene id: 1136941:ACH46_RS05670
uniprot id: A0A0N9N9J9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF beta-subunit/FixA family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1136941:ACH46 RS03695
gene id: 1136941:ACH46_RS03695
uniprot id: A0A0N9N744
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

1136941:ACH46 RS06205
gene id: 1136941:ACH46_RS06205
uniprot id: A0A0N9NEZ1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1136941:ACH46 RS08405
gene id: 1136941:ACH46_RS08405
uniprot id: A0A0N9N2P1
names: Similarity
messages: Belongs to the P(II) protein family.

1136941:ACH46 RS08640
gene id: 1136941:ACH46_RS08640
uniprot id: A0A0N9NGF6
names: Similarity
messages: Belongs to the MQO family.

1136941:ACH46 RS07480
gene id: 1136941:ACH46_RS07480
uniprot id: A0A0N9N2D7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1136941:ACH46 RS02230
gene id: 1136941:ACH46_RS02230
uniprot id: A0A0N9N975
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1136941:ACH46 RS11305
gene id: 1136941:ACH46_RS11305
uniprot id: A0A0N9N3R3
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

1136941:ACH46 RS13915
gene id: 1136941:ACH46_RS13915
uniprot id: A0A0N7FUV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1136941:ACH46 RS06425
gene id: 1136941:ACH46_RS06425
uniprot id: A0A0N9N804
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

1136941:ACH46 RS00740
gene id: 1136941:ACH46_RS00740
uniprot id: A0A0N9NDR9
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

1136941:ACH46 RS12660
gene id: 1136941:ACH46_RS12660
uniprot id: A0A0N9NI46
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS04865
gene id: 1136941:ACH46_RS04865
uniprot id: A0A0N9N9P3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

1136941:ACH46 RS03615
gene id: 1136941:ACH46_RS03615
uniprot id: A0A0N9N0W4
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

1136941:ACH46 RS04600
gene id: 1136941:ACH46_RS04600
uniprot id: A0A0N9NEB8
names: Similarity
messages: Belongs to the CdaR family.

1136941:ACH46 RS04825
gene id: 1136941:ACH46_RS04825
uniprot id: A0A0N9N7H2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1136941:ACH46 RS11190
gene id: 1136941:ACH46_RS11190
uniprot id: A0A0N9NHL5
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

1136941:ACH46 RS00415
gene id: 1136941:ACH46_RS00415
uniprot id: A0A0N9N674
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

1136941:ACH46 RS08960
gene id: 1136941:ACH46_RS08960
uniprot id: A0A0N9N2U4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

1136941:ACH46 RS12855
gene id: 1136941:ACH46_RS12855
uniprot id: A0A0N7FUS9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1136941:ACH46 RS15585
gene id: 1136941:ACH46_RS15585
uniprot id: A0A0N9MSZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1136941:ACH46 RS18875
gene id: 1136941:ACH46_RS18875
uniprot id: A0A0N9NEN1
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

1136941:ACH46 RS07215
gene id: 1136941:ACH46_RS07215
uniprot id: A0A0N9NAD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1136941:ACH46 RS01810
gene id: 1136941:ACH46_RS01810
uniprot id: A0A0N9MZD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

1136941:ACH46 RS19965
gene id: 1136941:ACH46_RS19965
uniprot id: A0A0N9MUQ4
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS15405
gene id: 1136941:ACH46_RS15405
uniprot id: A0A0N9N480
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1136941:ACH46 RS05675
gene id: 1136941:ACH46_RS05675
uniprot id: A0A0N9NFM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

1136941:ACH46 RS08610
gene id: 1136941:ACH46_RS08610
uniprot id: A0A0N9NAR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

1136941:ACH46 RS05055
gene id: 1136941:ACH46_RS05055
uniprot id: A0A0N9NFD9
names: Similarity
messages: Belongs to the TrpF family.

1136941:ACH46 RS18000
gene id: 1136941:ACH46_RS18000
uniprot id: A0A0N9NK45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1136941:ACH46 RS00280
gene id: 1136941:ACH46_RS00280
uniprot id: A0A0N9N651
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS14500
gene id: 1136941:ACH46_RS14500
uniprot id: A0A0N9N3U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1136941:ACH46 RS01605
gene id: 1136941:ACH46_RS01605
uniprot id: A0A0N9MZB9
names: Subcellular Location Annotation
messages: Cytoplasm

1136941:ACH46 RS16315
gene id: 1136941:ACH46_RS16315
uniprot id: A0A0N7FUZ8
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1136941:ACH46 RS07310
gene id: 1136941:ACH46_RS07310
uniprot id: A0A0N9MNI8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1136941:ACH46 RS07165
gene id: 1136941:ACH46_RS07165
uniprot id: A0A0N7FUG9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1136941:ACH46 RS04895
gene id: 1136941:ACH46_RS04895
uniprot id: A0A0N9MP75
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1136941:ACH46 RS06635
gene id: 1136941:ACH46_RS06635
uniprot id: A0A0N9NF50
names: Similarity
messages: Belongs to the FPG family.

1136941:ACH46 RS06710
gene id: 1136941:ACH46_RS06710
uniprot id: A0A0N9MNC2
names: Function
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.

1136941:ACH46 RS14305
gene id: 1136941:ACH46_RS14305
uniprot id: A0A0N9N4S2
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

1136941:ACH46 RS01765
gene id: 1136941:ACH46_RS01765
uniprot id: A0A0N9ND76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1136941:ACH46 RS00590
gene id: 1136941:ACH46_RS00590
uniprot id: A0A0N7FU38
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

1136941:ACH46 RS07115
gene id: 1136941:ACH46_RS07115
uniprot id: A0A0N9NBD1
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

1136941:ACH46 RS09935
gene id: 1136941:ACH46_RS09935
uniprot id: A0A0N9NGA9
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the maleate isomerase family.
messages: Catalyzes cis-trans isomerization of the C2-C3 double bond in maleate to yield fumarate.
messages: Homodimer.
messages: Reaction is initiated by nucleophilic attack of cysteine at the double bond, yielding a covalent succinylcysteine-like intermediate.

1136941:ACH46 RS19770
gene id: 1136941:ACH46_RS19770
uniprot id: A0A0N9MUM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

1136941:ACH46 RS02330
gene id: 1136941:ACH46_RS02330
uniprot id: A0A0N9N8V8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1136941:ACH46 RS01515
gene id: 1136941:ACH46_RS01515
uniprot id: A0A0N7FU57
names: Function
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: May catalyze the transamination reaction in phenylalanine biosynthesis.

1136941:ACH46 RS17475
gene id: 1136941:ACH46_RS17475
uniprot id: A0A0N9NE05
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1136941:ACH46 RS05660
gene id: 1136941:ACH46_RS05660
uniprot id: A0A0N9MPF5
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

1136941:ACH46 RS15210
gene id: 1136941:ACH46_RS15210
uniprot id: A0A0N9N447
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1136941:ACH46 RS02240
gene id: 1136941:ACH46_RS02240
uniprot id: A0A0N9NE64
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.

1136941:ACH46 RS06295
gene id: 1136941:ACH46_RS06295
uniprot id: A0A0N9MPQ2
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS14555
gene id: 1136941:ACH46_RS14555
uniprot id: A0A0N7FUW2
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

1136941:ACH46 RS06765
gene id: 1136941:ACH46_RS06765
uniprot id: A0A0N9N0Y1
names: Similarity
messages: Belongs to the SufE family.

1136941:ACH46 RS02890
gene id: 1136941:ACH46_RS02890
uniprot id: A0A0N9N9H5
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1136941:ACH46 RS07655
gene id: 1136941:ACH46_RS07655
uniprot id: A0A0N9NA89
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

1136941:ACH46 RS03215
gene id: 1136941:ACH46_RS03215
uniprot id: A0A0N9N0S2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1136941:ACH46 RS09990
gene id: 1136941:ACH46_RS09990
uniprot id: A0A0N9N7U8
names: Caution
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS19585
gene id: 1136941:ACH46_RS19585
uniprot id: A0A0N9NF16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

1136941:ACH46 RS20650
gene id: 1136941:ACH46_RS20650
uniprot id: A0A0N9ND89
names: Similarity
messages: Belongs to the thioredoxin family.

1136941:ACH46 RS18405
gene id: 1136941:ACH46_RS18405
uniprot id: A0A0N9NJG8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

1136941:ACH46 RS19110
gene id: 1136941:ACH46_RS19110
uniprot id: A0A0N9NEU9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1136941:ACH46 RS04515
gene id: 1136941:ACH46_RS04515
uniprot id: A0A0N9NFU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Cell membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

1136941:ACH46 RS08535
gene id: 1136941:ACH46_RS08535
uniprot id: A0A0N9NGN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1136941:ACH46 RS06145
gene id: 1136941:ACH46_RS06145
uniprot id: A0A0N9N1Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily.
messages: Periplasm

1136941:ACH46 RS14455
gene id: 1136941:ACH46_RS14455
uniprot id: A0A0N9NAR3
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1136941:ACH46 RS08935
gene id: 1136941:ACH46_RS08935
uniprot id: A0A0N9NAV7
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1136941:ACH46 RS12135
gene id: 1136941:ACH46_RS12135
uniprot id: A0A0N9MRM1
names: Similarity
messages: Belongs to the TrpC family.

1136941:ACH46 RS19460
gene id: 1136941:ACH46_RS19460
uniprot id: A0A0N9NJV4
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS12265
gene id: 1136941:ACH46_RS12265
uniprot id: A0A0N9NGQ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1136941:ACH46 RS07145
gene id: 1136941:ACH46_RS07145
uniprot id: A0A0N9MNF3
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

1136941:ACH46 RS01650
gene id: 1136941:ACH46_RS01650
uniprot id: A0A0N9N8B1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

1136941:ACH46 RS06550
gene id: 1136941:ACH46_RS06550
uniprot id: A0A0N9MNB2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1136941:ACH46 RS02150
gene id: 1136941:ACH46_RS02150
uniprot id: A0A0N9MN76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1136941:ACH46 RS04220
gene id: 1136941:ACH46_RS04220
uniprot id: A0A0N9NF38
names: Similarity
messages: Belongs to the AHA1 family.

1136941:ACH46 RS18700
gene id: 1136941:ACH46_RS18700
uniprot id: A0A0N7FV47
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1136941:ACH46 RS18330
gene id: 1136941:ACH46_RS18330
uniprot id: A0A0N9NH81
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1136941:ACH46 RS18290
gene id: 1136941:ACH46_RS18290
uniprot id: A0A0N9N040
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

1136941:ACH46 RS11085
gene id: 1136941:ACH46_RS11085
uniprot id: A0A0N7FUP6
names: Similarity
messages: Belongs to the pirin family.

1136941:ACH46 RS09875
gene id: 1136941:ACH46_RS09875
uniprot id: A0A0N9NGA1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS07910
gene id: 1136941:ACH46_RS07910
uniprot id: A0A0N7FUI3
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1136941:ACH46 RS15380
gene id: 1136941:ACH46_RS15380
uniprot id: A0A0N7FUX9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1136941:ACH46 RS01840
gene id: 1136941:ACH46_RS01840
uniprot id: A0A0N9NDF5
names: Subcellular Location Annotation
messages: Membrane

1136941:ACH46 RS15335
gene id: 1136941:ACH46_RS15335
uniprot id: A0A0N9NJ31
names: Similarity
messages: Belongs to the WXG100 family.