1134435:AC731 RS15620
gene id: 1134435:AC731_RS15620
uniprot id: A0A127K8F0
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1134435:AC731 RS17625
gene id: 1134435:AC731_RS17625
uniprot id: A0A127K9F7
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

1134435:AC731 RS08035
gene id: 1134435:AC731_RS08035
uniprot id: A0A127K5G8
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS01150
gene id: 1134435:AC731_RS01150
uniprot id: A0A140ID50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

1134435:AC731 RS14595
gene id: 1134435:AC731_RS14595
uniprot id: A0A127K7W2
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS05870
gene id: 1134435:AC731_RS05870
uniprot id: A0A127K3H8
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS01325
gene id: 1134435:AC731_RS01325
uniprot id: A0A140ID81
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1134435:AC731 RS04685
gene id: 1134435:AC731_RS04685
uniprot id: A0A127K2V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1134435:AC731 RS01135
gene id: 1134435:AC731_RS01135
uniprot id: A0A140ID47
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1134435:AC731 RS16615
gene id: 1134435:AC731_RS16615
uniprot id: A0A127K9R8
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

1134435:AC731 RS18195
gene id: 1134435:AC731_RS18195
uniprot id: A0A127K9S9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS03300
gene id: 1134435:AC731_RS03300
uniprot id: A0A140IE73
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

1134435:AC731 RS10540
gene id: 1134435:AC731_RS10540
uniprot id: A0A127K6R5
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

1134435:AC731 RS11095
gene id: 1134435:AC731_RS11095
uniprot id: A0A127K691
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1134435:AC731 RS01270
gene id: 1134435:AC731_RS01270
uniprot id: A0A140ID71
names: Similarity
messages: Belongs to the type III secretion exporter family.

1134435:AC731 RS14885
gene id: 1134435:AC731_RS14885
uniprot id: A0A127K812
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS06120
gene id: 1134435:AC731_RS06120
uniprot id: A0A127K3L0
names: Similarity
messages: Belongs to the threonine synthase family.

1134435:AC731 RS02955
gene id: 1134435:AC731_RS02955
uniprot id: A0A140IE16
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS04610
gene id: 1134435:AC731_RS04610
uniprot id: A0A127KAR0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1134435:AC731 RS12010
gene id: 1134435:AC731_RS12010
uniprot id: A0A127K6P7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS12930
gene id: 1134435:AC731_RS12930
uniprot id: A0A127K742
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

1134435:AC731 RS15530
gene id: 1134435:AC731_RS15530
uniprot id: A0A127K978
names: Similarity
messages: Belongs to the IMPACT family.

1134435:AC731 RS01770
gene id: 1134435:AC731_RS01770
uniprot id: A0A140IDF9
names: Similarity
messages: Belongs to the TmoD/XamoD family.

1134435:AC731 RS06065
gene id: 1134435:AC731_RS06065
uniprot id: A0A127K3K8
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1134435:AC731 RS03590
gene id: 1134435:AC731_RS03590
uniprot id: A0A140IEC6
names: Similarity
messages: Belongs to the class-C beta-lactamase family.

1134435:AC731 RS15535
gene id: 1134435:AC731_RS15535
uniprot id: A0A127K8D8
names: Similarity
messages: Belongs to the Dps family.

1134435:AC731 RS06795
gene id: 1134435:AC731_RS06795
uniprot id: A0A127K400
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

1134435:AC731 RS17535
gene id: 1134435:AC731_RS17535
uniprot id: A0A127K9D5
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

1134435:AC731 RS10595
gene id: 1134435:AC731_RS10595
uniprot id: A0A127K5X3
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1134435:AC731 RS00735
gene id: 1134435:AC731_RS00735
uniprot id: A0A140ICX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbiQ family.
messages: Membrane

1134435:AC731 RS03270
gene id: 1134435:AC731_RS03270
uniprot id: A0A127KBB4
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS19100
gene id: 1134435:AC731_RS19100
uniprot id: A0A127KB16
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

1134435:AC731 RS02295
gene id: 1134435:AC731_RS02295
uniprot id: A0A140IDQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

1134435:AC731 RS07700
gene id: 1134435:AC731_RS07700
uniprot id: A0A127K4G0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

1134435:AC731 RS16015
gene id: 1134435:AC731_RS16015
uniprot id: A0A127K8N9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

1134435:AC731 RS05190
gene id: 1134435:AC731_RS05190
uniprot id: A0A127K342
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

1134435:AC731 RS05565
gene id: 1134435:AC731_RS05565
uniprot id: A0A127K3B6
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

1134435:AC731 RS17410
gene id: 1134435:AC731_RS17410
uniprot id: A0A127KA70
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1134435:AC731 RS13845
gene id: 1134435:AC731_RS13845
uniprot id: A0A127K7H7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

1134435:AC731 RS11820
gene id: 1134435:AC731_RS11820
uniprot id: A0A127K6H2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1134435:AC731 RS11545
gene id: 1134435:AC731_RS11545
uniprot id: A0A127K6E3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

1134435:AC731 RS09210
gene id: 1134435:AC731_RS09210
uniprot id: A0A127K575
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

1134435:AC731 RS12095
gene id: 1134435:AC731_RS12095
uniprot id: A0A127K6L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1134435:AC731 RS12125
gene id: 1134435:AC731_RS12125
uniprot id: A0A127K6S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1134435:AC731 RS17920
gene id: 1134435:AC731_RS17920
uniprot id: A0A127K9M9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1134435:AC731 RS19350
gene id: 1134435:AC731_RS19350
uniprot id: A0A127KAC8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters.

1134435:AC731 RS06910
gene id: 1134435:AC731_RS06910
uniprot id: A0A127K406
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

1134435:AC731 RS16825
gene id: 1134435:AC731_RS16825
uniprot id: A0A127K915
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS00220
gene id: 1134435:AC731_RS00220
uniprot id: A0A140ICP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1134435:AC731 RS15005
gene id: 1134435:AC731_RS15005
uniprot id: A0A127K852
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.

1134435:AC731 RS12675
gene id: 1134435:AC731_RS12675
uniprot id: A0A127K7R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

1134435:AC731 RS05815
gene id: 1134435:AC731_RS05815
uniprot id: A0A127K4G1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

1134435:AC731 RS09730
gene id: 1134435:AC731_RS09730
uniprot id: A0A127K5H9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

1134435:AC731 RS14415
gene id: 1134435:AC731_RS14415
uniprot id: A0A127K7T3
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS18830
gene id: 1134435:AC731_RS18830
uniprot id: A0A127KA20
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

1134435:AC731 RS02830
gene id: 1134435:AC731_RS02830
uniprot id: A0A140IDZ2
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1134435:AC731 RS01175
gene id: 1134435:AC731_RS01175
uniprot id: A0A140ID55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1134435:AC731 RS01485
gene id: 1134435:AC731_RS01485
uniprot id: A0A140IDB0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.
messages: Belongs to the type-I restriction system S methylase family.

1134435:AC731 RS16515
gene id: 1134435:AC731_RS16515
uniprot id: A0A127K8V1
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1134435:AC731 RS01215
gene id: 1134435:AC731_RS01215
uniprot id: A0A140ID62
names: Subcellular Location Annotation
messages: Cytoplasm

1134435:AC731 RS16645
gene id: 1134435:AC731_RS16645
uniprot id: A0A127K8X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

1134435:AC731 RS12855
gene id: 1134435:AC731_RS12855
uniprot id: A0A127K704
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1134435:AC731 RS17260
gene id: 1134435:AC731_RS17260
uniprot id: A0A127K9B0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

1134435:AC731 RS16440
gene id: 1134435:AC731_RS16440
uniprot id: A0A127K8Y9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1134435:AC731 RS18310
gene id: 1134435:AC731_RS18310
uniprot id: A0A127K9U9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1134435:AC731 RS01400
gene id: 1134435:AC731_RS01400
uniprot id: A0A140ID96
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

1134435:AC731 RS02870
gene id: 1134435:AC731_RS02870
uniprot id: A0A140IE00
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

1134435:AC731 RS00865
gene id: 1134435:AC731_RS00865
uniprot id: A0A140ID03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1134435:AC731 RS11360
gene id: 1134435:AC731_RS11360
uniprot id: A0A127K697
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

1134435:AC731 RS18565
gene id: 1134435:AC731_RS18565
uniprot id: A0A127K9Y1
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

1134435:AC731 RS08700
gene id: 1134435:AC731_RS08700
uniprot id: A0A127K4X7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1134435:AC731 RS03310
gene id: 1134435:AC731_RS03310
uniprot id: A0A140IE75
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

1134435:AC731 RS01145
gene id: 1134435:AC731_RS01145
uniprot id: A0A140ID49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1134435:AC731 RS18955
gene id: 1134435:AC731_RS18955
uniprot id: A0A127KA40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

1134435:AC731 RS16380
gene id: 1134435:AC731_RS16380
uniprot id: A0A127K904
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1134435:AC731 RS15400
gene id: 1134435:AC731_RS15400
uniprot id: A0A127K8B7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1134435:AC731 RS06195
gene id: 1134435:AC731_RS06195
uniprot id: A0A127K3N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1134435:AC731 RS13680
gene id: 1134435:AC731_RS13680
uniprot id: A0A127K7H8
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS11450
gene id: 1134435:AC731_RS11450
uniprot id: A0A127K6B7
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS19175
gene id: 1134435:AC731_RS19175
uniprot id: A0A127KAA2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

1134435:AC731 RS11655
gene id: 1134435:AC731_RS11655
uniprot id: A0A127K6I7
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

1134435:AC731 RS01805
gene id: 1134435:AC731_RS01805
uniprot id: A0A140IDG6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1134435:AC731 RS09215
gene id: 1134435:AC731_RS09215
uniprot id: A0A127K577
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1134435:AC731 RS16770
gene id: 1134435:AC731_RS16770
uniprot id: A0A127K903
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1134435:AC731 RS14485
gene id: 1134435:AC731_RS14485
uniprot id: A0A127K7U3
names: Function
names: Subcellular Location Annotation
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

1134435:AC731 RS14900
gene id: 1134435:AC731_RS14900
uniprot id: A0A127K833
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1134435:AC731 RS10185
gene id: 1134435:AC731_RS10185
uniprot id: A0A127K5Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1134435:AC731 RS18995
gene id: 1134435:AC731_RS18995
uniprot id: A0A127KA72
names: Function
names: Similarity
messages: Belongs to the DadA oxidoreductase family.
messages: Oxidative deamination of D-amino acids.

1134435:AC731 RS03365
gene id: 1134435:AC731_RS03365
uniprot id: A0A140IE85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

1134435:AC731 RS07545
gene id: 1134435:AC731_RS07545
uniprot id: A0A127K4E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1134435:AC731 RS13075
gene id: 1134435:AC731_RS13075
uniprot id: A0A127K740
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

1134435:AC731 RS08340
gene id: 1134435:AC731_RS08340
uniprot id: A0A127K4R3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

1134435:AC731 RS05830
gene id: 1134435:AC731_RS05830
uniprot id: A0A127K3G3
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

1134435:AC731 RS11405
gene id: 1134435:AC731_RS11405
uniprot id: A0A127K758
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

1134435:AC731 RS07540
gene id: 1134435:AC731_RS07540
uniprot id: A0A127K4D8
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

1134435:AC731 RS06790
gene id: 1134435:AC731_RS06790
uniprot id: A0A127K4W9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

1134435:AC731 RS00520
gene id: 1134435:AC731_RS00520
uniprot id: A0A140ICU3
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS02585
gene id: 1134435:AC731_RS02585
uniprot id: A0A140IDV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1134435:AC731 RS09715
gene id: 1134435:AC731_RS09715
uniprot id: A0A127K5I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1134435:AC731 RS06825
gene id: 1134435:AC731_RS06825
uniprot id: A0A127K3Z1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1134435:AC731 RS16235
gene id: 1134435:AC731_RS16235
uniprot id: A0A127K9J5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1134435:AC731 RS04135
gene id: 1134435:AC731_RS04135
uniprot id: A0A140IEM1
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS07405
gene id: 1134435:AC731_RS07405
uniprot id: A0A127K4A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

1134435:AC731 RS06075
gene id: 1134435:AC731_RS06075
uniprot id: A0A127K3J5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

1134435:AC731 RS02590
gene id: 1134435:AC731_RS02590
uniprot id: A0A127KAH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1134435:AC731 RS05570
gene id: 1134435:AC731_RS05570
uniprot id: A0A127K3B7
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

1134435:AC731 RS07360
gene id: 1134435:AC731_RS07360
uniprot id: A0A127K490
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

1134435:AC731 RS02140
gene id: 1134435:AC731_RS02140
uniprot id: A0A140IDM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1134435:AC731 RS12610
gene id: 1134435:AC731_RS12610
uniprot id: A0A127K7Q8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PriB family.
messages: Binds single-stranded DNA at the primosome assembly site (PAS).
messages: Component of the preprimosomal complex composed of PriA, PriB, PriC, DnaB and DnaT. Upon transient interaction with DnaG it forms the primosome.

1134435:AC731 RS14935
gene id: 1134435:AC731_RS14935
uniprot id: A0A127K823
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1134435:AC731 RS11055
gene id: 1134435:AC731_RS11055
uniprot id: A0A127K6Z3
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS02835
gene id: 1134435:AC731_RS02835
uniprot id: A0A140IDZ3
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

1134435:AC731 RS02055
gene id: 1134435:AC731_RS02055
uniprot id: A0A140IDL1
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

1134435:AC731 RS02635
gene id: 1134435:AC731_RS02635
uniprot id: A0A140IDV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1134435:AC731 RS05685
gene id: 1134435:AC731_RS05685
uniprot id: A0A127K3D4
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
messages: Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).

1134435:AC731 RS11875
gene id: 1134435:AC731_RS11875
uniprot id: A0A127K6H5
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS11495
gene id: 1134435:AC731_RS11495
uniprot id: A0A127K6D8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

1134435:AC731 RS08330
gene id: 1134435:AC731_RS08330
uniprot id: A0A127K4R2
names: Similarity
messages: Belongs to the universal stress protein A family.

1134435:AC731 RS05205
gene id: 1134435:AC731_RS05205
uniprot id: A0A127K349
names: Similarity
messages: Belongs to the HesB/IscA family.

1134435:AC731 RS18940
gene id: 1134435:AC731_RS18940
uniprot id: A0A127KA64
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS13000
gene id: 1134435:AC731_RS13000
uniprot id: A0A127K754
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

1134435:AC731 RS03385
gene id: 1134435:AC731_RS03385
uniprot id: A0A140IE88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1134435:AC731 RS05090
gene id: 1134435:AC731_RS05090
uniprot id: A0A127K321
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

1134435:AC731 RS08730
gene id: 1134435:AC731_RS08730
uniprot id: A0A127K4Z4
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS10980
gene id: 1134435:AC731_RS10980
uniprot id: A0A127K671
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1134435:AC731 RS14580
gene id: 1134435:AC731_RS14580
uniprot id: A0A127K7W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1134435:AC731 RS12050
gene id: 1134435:AC731_RS12050
uniprot id: A0A127K6Q7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein.
messages: Oligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.

1134435:AC731 RS09350
gene id: 1134435:AC731_RS09350
uniprot id: A0A127K5A5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

1134435:AC731 RS05125
gene id: 1134435:AC731_RS05125
uniprot id: A0A127K339
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage.

1134435:AC731 RS15450
gene id: 1134435:AC731_RS15450
uniprot id: A0A127K8C7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1134435:AC731 RS01225
gene id: 1134435:AC731_RS01225
uniprot id: A0A140ID64
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

1134435:AC731 RS11325
gene id: 1134435:AC731_RS11325
uniprot id: A0A127K682
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS15235
gene id: 1134435:AC731_RS15235
uniprot id: A0A127K871
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS02120
gene id: 1134435:AC731_RS02120
uniprot id: A0A140IDM2
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

1134435:AC731 RS09985
gene id: 1134435:AC731_RS09985
uniprot id: A0A127K5M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

1134435:AC731 RS18855
gene id: 1134435:AC731_RS18855
uniprot id: A0A127KA21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

1134435:AC731 RS11635
gene id: 1134435:AC731_RS11635
uniprot id: A0A127K6E9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

1134435:AC731 RS03175
gene id: 1134435:AC731_RS03175
uniprot id: A0A140IE51
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1134435:AC731 RS08480
gene id: 1134435:AC731_RS08480
uniprot id: A0A127K4V7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1134435:AC731 RS05660
gene id: 1134435:AC731_RS05660
uniprot id: A0A127K3D8
names: Similarity
messages: Belongs to the ArsC family.

1134435:AC731 RS17355
gene id: 1134435:AC731_RS17355
uniprot id: A0A127K9B7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

1134435:AC731 RS11840
gene id: 1134435:AC731_RS11840
uniprot id: A0A127K6M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1134435:AC731 RS02285
gene id: 1134435:AC731_RS02285
uniprot id: A0A140IDQ1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

1134435:AC731 RS13045
gene id: 1134435:AC731_RS13045
uniprot id: A0A127K741
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

1134435:AC731 RS00810
gene id: 1134435:AC731_RS00810
uniprot id: A0A140ICZ3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

1134435:AC731 RS18370
gene id: 1134435:AC731_RS18370
uniprot id: A0A127K9W1
names: Similarity
messages: Belongs to the SCO1/2 family.

1134435:AC731 RS06740
gene id: 1134435:AC731_RS06740
uniprot id: A0A127K4V8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

1134435:AC731 RS17485
gene id: 1134435:AC731_RS17485
uniprot id: A0A127K9F1
names: Similarity
messages: Belongs to the RutC family.

1134435:AC731 RS04555
gene id: 1134435:AC731_RS04555
uniprot id: A0A127KAJ8
names: Similarity
messages: Belongs to the GppA/Ppx family.

1134435:AC731 RS11045
gene id: 1134435:AC731_RS11045
uniprot id: A0A127K649
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1134435:AC731 RS07975
gene id: 1134435:AC731_RS07975
uniprot id: A0A127K5F3
names: Similarity
messages: Belongs to the asparagine synthetase family.

1134435:AC731 RS03250
gene id: 1134435:AC731_RS03250
uniprot id: A0A140IE65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

1134435:AC731 RS10240
gene id: 1134435:AC731_RS10240
uniprot id: A0A127K5Q8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

1134435:AC731 RS13175
gene id: 1134435:AC731_RS13175
uniprot id: A0A127K808
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1134435:AC731 RS02145
gene id: 1134435:AC731_RS02145
uniprot id: A0A140IDM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1134435:AC731 RS17435
gene id: 1134435:AC731_RS17435
uniprot id: A0A127K9E1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1134435:AC731 RS11395
gene id: 1134435:AC731_RS11395
uniprot id: A0A127K6A7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

1134435:AC731 RS18875
gene id: 1134435:AC731_RS18875
uniprot id: A0A127KA49
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

1134435:AC731 RS14080
gene id: 1134435:AC731_RS14080
uniprot id: A0A127K7Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

1134435:AC731 RS13070
gene id: 1134435:AC731_RS13070
uniprot id: A0A127K7Y4
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

1134435:AC731 RS10560
gene id: 1134435:AC731_RS10560
uniprot id: A0A127K5V7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

1134435:AC731 RS10085
gene id: 1134435:AC731_RS10085
uniprot id: A0A127K5P0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

1134435:AC731 RS05700
gene id: 1134435:AC731_RS05700
uniprot id: A0A127K3D2
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TorC/TorY family.
messages: Binds 5 heme groups per subunit.
messages: Cell inner membrane
messages: Membrane

1134435:AC731 RS12145
gene id: 1134435:AC731_RS12145
uniprot id: A0A127K6N5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1134435:AC731 RS19130
gene id: 1134435:AC731_RS19130
uniprot id: A0A127KA83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1134435:AC731 RS04550
gene id: 1134435:AC731_RS04550
uniprot id: A0A127K2T7
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

1134435:AC731 RS16925
gene id: 1134435:AC731_RS16925
uniprot id: A0A127K931
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

1134435:AC731 RS00475
gene id: 1134435:AC731_RS00475
uniprot id: A0A140ICT7
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1134435:AC731 RS00790
gene id: 1134435:AC731_RS00790
uniprot id: A0A140ICY9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1134435:AC731 RS11825
gene id: 1134435:AC731_RS11825
uniprot id: A0A127K6H0
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS09120
gene id: 1134435:AC731_RS09120
uniprot id: A0A127K560
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS13565
gene id: 1134435:AC731_RS13565
uniprot id: A0A127K7C8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

1134435:AC731 RS11125
gene id: 1134435:AC731_RS11125
uniprot id: A0A127K660
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS15085
gene id: 1134435:AC731_RS15085
uniprot id: A0A127K879
names: Subcellular Location Annotation
messages: Cytoplasm

1134435:AC731 RS01680
gene id: 1134435:AC731_RS01680
uniprot id: A0A140IDE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1134435:AC731 RS14590
gene id: 1134435:AC731_RS14590
uniprot id: A0A127K7X9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1134435:AC731 RS05235
gene id: 1134435:AC731_RS05235
uniprot id: A0A127K356
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

1134435:AC731 RS18225
gene id: 1134435:AC731_RS18225
uniprot id: A0A127K9S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

1134435:AC731 RS18500
gene id: 1134435:AC731_RS18500
uniprot id: A0A127KB75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1134435:AC731 RS08750
gene id: 1134435:AC731_RS08750
uniprot id: A0A127K4Z3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1134435:AC731 RS05170
gene id: 1134435:AC731_RS05170
uniprot id: A0A127K341
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

1134435:AC731 RS06760
gene id: 1134435:AC731_RS06760
uniprot id: A0A127K3Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

1134435:AC731 RS06055
gene id: 1134435:AC731_RS06055
uniprot id: A0A127K3K3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1134435:AC731 RS11660
gene id: 1134435:AC731_RS11660
uniprot id: A0A127K6F8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS06775
gene id: 1134435:AC731_RS06775
uniprot id: A0A127K3X8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

1134435:AC731 RS18915
gene id: 1134435:AC731_RS18915
uniprot id: A0A127KA76
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS19105
gene id: 1134435:AC731_RS19105
uniprot id: A0A127KA67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

1134435:AC731 RS00420
gene id: 1134435:AC731_RS00420
uniprot id: A0A140ICS7
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS12305
gene id: 1134435:AC731_RS12305
uniprot id: A0A127K6R3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

1134435:AC731 RS10745
gene id: 1134435:AC731_RS10745
uniprot id: A0A127K625
names: Similarity
messages: Belongs to the bacterial secretin family.

1134435:AC731 RS09785
gene id: 1134435:AC731_RS09785
uniprot id: A0A127K5J1
names: Similarity
messages: Belongs to the UPF0307 family.

1134435:AC731 RS06315
gene id: 1134435:AC731_RS06315
uniprot id: A0A127K3Q4
names: Similarity
messages: Belongs to the Ahb/Nir family.

1134435:AC731 RS14350
gene id: 1134435:AC731_RS14350
uniprot id: A0A127K7T6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1134435:AC731 RS12755
gene id: 1134435:AC731_RS12755
uniprot id: A0A127K714
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.

1134435:AC731 RS15470
gene id: 1134435:AC731_RS15470
uniprot id: A0A127K8D2
names: Similarity
messages: Belongs to the hemerythrin family.

1134435:AC731 RS02005
gene id: 1134435:AC731_RS02005
uniprot id: A0A140IDK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1134435:AC731 RS11835
gene id: 1134435:AC731_RS11835
uniprot id: A0A127K6J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1134435:AC731 RS14275
gene id: 1134435:AC731_RS14275
uniprot id: A0A127KAZ0
names: Similarity
messages: Belongs to the CobH/CbiC family.

1134435:AC731 RS05135
gene id: 1134435:AC731_RS05135
uniprot id: A0A127K332
names: Similarity
messages: Belongs to the UDPGP type 2 family.

1134435:AC731 RS18860
gene id: 1134435:AC731_RS18860
uniprot id: A0A127KAX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

1134435:AC731 RS02790
gene id: 1134435:AC731_RS02790
uniprot id: A0A140IDY4
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS01170
gene id: 1134435:AC731_RS01170
uniprot id: A0A140ID54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

1134435:AC731 RS00170
gene id: 1134435:AC731_RS00170
uniprot id: A0A140ICN3
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS03775
gene id: 1134435:AC731_RS03775
uniprot id: A0A140IEF7
names: Similarity
messages: Belongs to the YkuD family.

1134435:AC731 RS01970
gene id: 1134435:AC731_RS01970
uniprot id: A0A140IDJ4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS01115
gene id: 1134435:AC731_RS01115
uniprot id: A0A140ID43
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1134435:AC731 RS11515
gene id: 1134435:AC731_RS11515
uniprot id: A0A127K778
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

1134435:AC731 RS01790
gene id: 1134435:AC731_RS01790
uniprot id: A0A140IDG3
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

1134435:AC731 RS13245
gene id: 1134435:AC731_RS13245
uniprot id: A0A127K776
names: Similarity
messages: Belongs to the LOG family.

1134435:AC731 RS00915
gene id: 1134435:AC731_RS00915
uniprot id: A0A140ID09
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

1134435:AC731 RS01670
gene id: 1134435:AC731_RS01670
uniprot id: A0A140IDE0
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

1134435:AC731 RS16295
gene id: 1134435:AC731_RS16295
uniprot id: A0A127K8R2
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

1134435:AC731 RS05585
gene id: 1134435:AC731_RS05585
uniprot id: A0A127K3B4
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

1134435:AC731 RS18545
gene id: 1134435:AC731_RS18545
uniprot id: A0A127K9Y3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

1134435:AC731 RS00905
gene id: 1134435:AC731_RS00905
uniprot id: A0A140ID08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

1134435:AC731 RS15300
gene id: 1134435:AC731_RS15300
uniprot id: A0A127K881
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1134435:AC731 RS07280
gene id: 1134435:AC731_RS07280
uniprot id: A0A127K546
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

1134435:AC731 RS05035
gene id: 1134435:AC731_RS05035
uniprot id: A0A127K314
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

1134435:AC731 RS16340
gene id: 1134435:AC731_RS16340
uniprot id: A0A127K9L4
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS08045
gene id: 1134435:AC731_RS08045
uniprot id: A0A127K4M6
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1134435:AC731 RS10005
gene id: 1134435:AC731_RS10005
uniprot id: A0A127K5L8
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1134435:AC731 RS11085
gene id: 1134435:AC731_RS11085
uniprot id: A0A127K684
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

1134435:AC731 RS10490
gene id: 1134435:AC731_RS10490
uniprot id: A0A127K5Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

1134435:AC731 RS13405
gene id: 1134435:AC731_RS13405
uniprot id: A0A127K7A6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

1134435:AC731 RS14135
gene id: 1134435:AC731_RS14135
uniprot id: A0A127K7P6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1134435:AC731 RS00130
gene id: 1134435:AC731_RS00130
uniprot id: A0A140ICM5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SoxA family.
messages: Binds 2 heme groups per subunit.
messages: Heterodimer of SoxA and SoxX.
messages: Periplasm

1134435:AC731 RS03375
gene id: 1134435:AC731_RS03375
uniprot id: A0A140IE87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

1134435:AC731 RS18290
gene id: 1134435:AC731_RS18290
uniprot id: A0A127K9T2
names: Similarity
messages: Belongs to the CFA/CMAS family.

1134435:AC731 RS00180
gene id: 1134435:AC731_RS00180
uniprot id: A0A140ICN5
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS10650
gene id: 1134435:AC731_RS10650
uniprot id: A0A127K6T3
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

1134435:AC731 RS00040
gene id: 1134435:AC731_RS00040
uniprot id: A0A140ICK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

1134435:AC731 RS07735
gene id: 1134435:AC731_RS07735
uniprot id: A0A127K5C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

1134435:AC731 RS10180
gene id: 1134435:AC731_RS10180
uniprot id: A0A127K5S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

1134435:AC731 RS06905
gene id: 1134435:AC731_RS06905
uniprot id: A0A127K3Z7
names: Similarity
messages: Belongs to the peptidase S16 family.

1134435:AC731 RS13320
gene id: 1134435:AC731_RS13320
uniprot id: A0A127K791
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

1134435:AC731 RS14770
gene id: 1134435:AC731_RS14770
uniprot id: A0A127K807
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1134435:AC731 RS11550
gene id: 1134435:AC731_RS11550
uniprot id: A0A127K6H1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

1134435:AC731 RS12345
gene id: 1134435:AC731_RS12345
uniprot id: A0A127K6S3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

1134435:AC731 RS09975
gene id: 1134435:AC731_RS09975
uniprot id: A0A127K5L2
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.

1134435:AC731 RS10925
gene id: 1134435:AC731_RS10925
uniprot id: A0A127K661
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

1134435:AC731 RS14820
gene id: 1134435:AC731_RS14820
uniprot id: A0A127K802
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

1134435:AC731 RS02620
gene id: 1134435:AC731_RS02620
uniprot id: A0A140IDV6
names: Function
names: Similarity
messages: Belongs to the SsuD family.
messages: Catalyzes the desulfonation of aliphatic sulfonates.

1134435:AC731 RS06325
gene id: 1134435:AC731_RS06325
uniprot id: A0A127K3R0
names: Similarity
messages: Belongs to the Ahb/Nir family.

1134435:AC731 RS07840
gene id: 1134435:AC731_RS07840
uniprot id: A0A127KAV2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1134435:AC731 RS04150
gene id: 1134435:AC731_RS04150
uniprot id: A0A140IEM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

1134435:AC731 RS07355
gene id: 1134435:AC731_RS07355
uniprot id: A0A127K491
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

1134435:AC731 RS15330
gene id: 1134435:AC731_RS15330
uniprot id: A0A127K899
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Member of a two-component regulatory system.

1134435:AC731 RS00655
gene id: 1134435:AC731_RS00655
uniprot id: A0A127KAD0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS16755
gene id: 1134435:AC731_RS16755
uniprot id: A0A127K948
names: Similarity
messages: Belongs to the thioesterase PaaI family.

1134435:AC731 RS07305
gene id: 1134435:AC731_RS07305
uniprot id: A0A127K481
names: Similarity
messages: Belongs to the glutathione peroxidase family.

1134435:AC731 RS01870
gene id: 1134435:AC731_RS01870
uniprot id: A0A140IDH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1134435:AC731 RS09950
gene id: 1134435:AC731_RS09950
uniprot id: A0A127K5M1
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1134435:AC731 RS00050
gene id: 1134435:AC731_RS00050
uniprot id: A0A127KAF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

1134435:AC731 RS17925
gene id: 1134435:AC731_RS17925
uniprot id: A0A127KBA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

1134435:AC731 RS08405
gene id: 1134435:AC731_RS08405
uniprot id: A0A127K4U1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1134435:AC731 RS17300
gene id: 1134435:AC731_RS17300
uniprot id: A0A127KA51
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

1134435:AC731 RS10900
gene id: 1134435:AC731_RS10900
uniprot id: A0A127K606
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

1134435:AC731 RS17395
gene id: 1134435:AC731_RS17395
uniprot id: A0A127K9J4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1134435:AC731 RS05230
gene id: 1134435:AC731_RS05230
uniprot id: A0A127K358
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

1134435:AC731 RS15775
gene id: 1134435:AC731_RS15775
uniprot id: A0A127K8H5
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1134435:AC731 RS09755
gene id: 1134435:AC731_RS09755
uniprot id: A0A127K5J3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1134435:AC731 RS16560
gene id: 1134435:AC731_RS16560
uniprot id: A0A127K8W2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

1134435:AC731 RS12265
gene id: 1134435:AC731_RS12265
uniprot id: A0A127K6T9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1134435:AC731 RS17120
gene id: 1134435:AC731_RS17120
uniprot id: A0A127K973
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1134435:AC731 RS04170
gene id: 1134435:AC731_RS04170
uniprot id: A0A140IEM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

1134435:AC731 RS10435
gene id: 1134435:AC731_RS10435
uniprot id: A0A127K5V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1134435:AC731 RS11645
gene id: 1134435:AC731_RS11645
uniprot id: A0A127K6J1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

1134435:AC731 RS11570
gene id: 1134435:AC731_RS11570
uniprot id: A0A127K787
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

1134435:AC731 RS16460
gene id: 1134435:AC731_RS16460
uniprot id: A0A127K8U1
names: Similarity
messages: Belongs to the thioredoxin family.

1134435:AC731 RS07785
gene id: 1134435:AC731_RS07785
uniprot id: A0A127K4G5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1134435:AC731 RS04050
gene id: 1134435:AC731_RS04050
uniprot id: A0A140IEK8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1134435:AC731 RS07930
gene id: 1134435:AC731_RS07930
uniprot id: A0A127K4J7
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1134435:AC731 RS16570
gene id: 1134435:AC731_RS16570
uniprot id: A0A127K8W1
names: Subcellular Location Annotation
messages: Mitochondrion

1134435:AC731 RS01285
gene id: 1134435:AC731_RS01285
uniprot id: A0A140ID74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

1134435:AC731 RS06860
gene id: 1134435:AC731_RS06860
uniprot id: A0A127K409
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

1134435:AC731 RS07450
gene id: 1134435:AC731_RS07450
uniprot id: A0A127K4B3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

1134435:AC731 RS19185
gene id: 1134435:AC731_RS19185
uniprot id: A0A127KA79
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

1134435:AC731 RS18805
gene id: 1134435:AC731_RS18805
uniprot id: A0A127KAW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

1134435:AC731 RS12685
gene id: 1134435:AC731_RS12685
uniprot id: A0A127K6X6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

1134435:AC731 RS01260
gene id: 1134435:AC731_RS01260
uniprot id: A0A140ID70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility.
messages: Bacterial flagellum basal body
messages: Belongs to the YcgR family.
messages: Monomer. Interacts with the flagellar basal bodies.

1134435:AC731 RS07965
gene id: 1134435:AC731_RS07965
uniprot id: A0A127K4J6
names: Similarity
messages: Belongs to the peptidase M42 family.

1134435:AC731 RS14395
gene id: 1134435:AC731_RS14395
uniprot id: A0A127K7Z9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS18015
gene id: 1134435:AC731_RS18015
uniprot id: A0A127KAH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane

1134435:AC731 RS15555
gene id: 1134435:AC731_RS15555
uniprot id: A0A127K8E9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

1134435:AC731 RS10955
gene id: 1134435:AC731_RS10955
uniprot id: A0A127K617
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

1134435:AC731 RS04980
gene id: 1134435:AC731_RS04980
uniprot id: A0A127K307
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

1134435:AC731 RS10590
gene id: 1134435:AC731_RS10590
uniprot id: A0A127K6S5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

1134435:AC731 RS10750
gene id: 1134435:AC731_RS10750
uniprot id: A0A127K607
names: Similarity
messages: Belongs to the GSP E family.

1134435:AC731 RS01010
gene id: 1134435:AC731_RS01010
uniprot id: A0A140ID25
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

1134435:AC731 RS10990
gene id: 1134435:AC731_RS10990
uniprot id: A0A127K645
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1134435:AC731 RS03645
gene id: 1134435:AC731_RS03645
uniprot id: A0A140IED5
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

1134435:AC731 RS09235
gene id: 1134435:AC731_RS09235
uniprot id: A0A127K580
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

1134435:AC731 RS17425
gene id: 1134435:AC731_RS17425
uniprot id: A0A127K9E0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1134435:AC731 RS05470
gene id: 1134435:AC731_RS05470
uniprot id: A0A127K390
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1134435:AC731 RS01410
gene id: 1134435:AC731_RS01410
uniprot id: A0A127KAG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

1134435:AC731 RS12190
gene id: 1134435:AC731_RS12190
uniprot id: A0A127K7J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

1134435:AC731 RS17175
gene id: 1134435:AC731_RS17175
uniprot id: A0A127K982
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

1134435:AC731 RS00575
gene id: 1134435:AC731_RS00575
uniprot id: A0A140ICV4
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

1134435:AC731 RS13365
gene id: 1134435:AC731_RS13365
uniprot id: A0A127K7F1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

1134435:AC731 RS12540
gene id: 1134435:AC731_RS12540
uniprot id: A0A127K6V7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1134435:AC731 RS06260
gene id: 1134435:AC731_RS06260
uniprot id: A0A127K3P5
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

1134435:AC731 RS07285
gene id: 1134435:AC731_RS07285
uniprot id: A0A127K486
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS14365
gene id: 1134435:AC731_RS14365
uniprot id: A0A127KBJ2
names: Similarity
messages: Belongs to the UxaA family.

1134435:AC731 RS04515
gene id: 1134435:AC731_RS04515
uniprot id: A0A127K2T6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS05115
gene id: 1134435:AC731_RS05115
uniprot id: A0A127K327
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

1134435:AC731 RS17235
gene id: 1134435:AC731_RS17235
uniprot id: A0A127KA42
names: Similarity
messages: Belongs to the UPF0178 family.

1134435:AC731 RS18770
gene id: 1134435:AC731_RS18770
uniprot id: A0A127KA10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1134435:AC731 RS06840
gene id: 1134435:AC731_RS06840
uniprot id: A0A127KAP4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

1134435:AC731 RS01995
gene id: 1134435:AC731_RS01995
uniprot id: A0A140IDJ9
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

1134435:AC731 RS13695
gene id: 1134435:AC731_RS13695
uniprot id: A0A127K890
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS05785
gene id: 1134435:AC731_RS05785
uniprot id: A0A127K3F9
names: Similarity
messages: Belongs to the CIA30 family.

1134435:AC731 RS04060
gene id: 1134435:AC731_RS04060
uniprot id: A0A140IEL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

1134435:AC731 RS09895
gene id: 1134435:AC731_RS09895
uniprot id: A0A127K5L0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

1134435:AC731 RS04970
gene id: 1134435:AC731_RS04970
uniprot id: A0A127K301
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

1134435:AC731 RS15525
gene id: 1134435:AC731_RS15525
uniprot id: A0A127K8E7
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

1134435:AC731 RS08200
gene id: 1134435:AC731_RS08200
uniprot id: A0A127K4Q2
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1134435:AC731 RS04625
gene id: 1134435:AC731_RS04625
uniprot id: A0A127K2U1
names: Similarity
messages: Belongs to the YciI family.

1134435:AC731 RS03315
gene id: 1134435:AC731_RS03315
uniprot id: A0A140IE76
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

1134435:AC731 RS10945
gene id: 1134435:AC731_RS10945
uniprot id: A0A127K6X7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1134435:AC731 RS18850
gene id: 1134435:AC731_RS18850
uniprot id: A0A127KA66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

1134435:AC731 RS08415
gene id: 1134435:AC731_RS08415
uniprot id: A0A127K4U3
names: Similarity
messages: Belongs to the TPP enzyme family.

1134435:AC731 RS03090
gene id: 1134435:AC731_RS03090
uniprot id: A0A140IE38
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

1134435:AC731 RS11110
gene id: 1134435:AC731_RS11110
uniprot id: A0A127K664
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Catalyzes the synthesis of activated sulfate.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1134435:AC731 RS18715
gene id: 1134435:AC731_RS18715
uniprot id: A0A127KA09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

1134435:AC731 RS07415
gene id: 1134435:AC731_RS07415
uniprot id: A0A127K4A0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

1134435:AC731 RS09925
gene id: 1134435:AC731_RS09925
uniprot id: A0A127K5K4
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

1134435:AC731 RS03130
gene id: 1134435:AC731_RS03130
uniprot id: A0A140IE44
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1134435:AC731 RS14980
gene id: 1134435:AC731_RS14980
uniprot id: A0A127K831
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapD family.
messages: Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

1134435:AC731 RS12285
gene id: 1134435:AC731_RS12285
uniprot id: A0A127K6R6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1134435:AC731 RS06250
gene id: 1134435:AC731_RS06250
uniprot id: A0A127K3P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1134435:AC731 RS09075
gene id: 1134435:AC731_RS09075
uniprot id: A0A127K557
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

1134435:AC731 RS15040
gene id: 1134435:AC731_RS15040
uniprot id: A0A127K844
names: Similarity
messages: Belongs to the thioredoxin family. DsbE subfamily.

1134435:AC731 RS02000
gene id: 1134435:AC731_RS02000
uniprot id: A0A140IDK0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

1134435:AC731 RS15390
gene id: 1134435:AC731_RS15390
uniprot id: A0A127K8C4
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

1134435:AC731 RS14475
gene id: 1134435:AC731_RS14475
uniprot id: A0A127K7U1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aromatic amine dehydrogenase heavy chain family.
messages: Methylamine dehydrogenase carries out the oxidation of methylamine. Electrons are passed from methylamine dehydrogenase to amicyanin.
messages: Periplasm
messages: Tetramer of two light and two heavy chains.

1134435:AC731 RS09635
gene id: 1134435:AC731_RS09635
uniprot id: A0A127K6B4
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS08125
gene id: 1134435:AC731_RS08125
uniprot id: A0A127K4M3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1134435:AC731 RS17950
gene id: 1134435:AC731_RS17950
uniprot id: A0A127K9R1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane.
messages: Periplasm

1134435:AC731 RS15255
gene id: 1134435:AC731_RS15255
uniprot id: A0A127K8B2
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS03685
gene id: 1134435:AC731_RS03685
uniprot id: A0A140IEE2
names: Similarity
messages: Belongs to the transposase 7 family.

1134435:AC731 RS04220
gene id: 1134435:AC731_RS04220
uniprot id: A0A140IEN4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1134435:AC731 RS13065
gene id: 1134435:AC731_RS13065
uniprot id: A0A127K739
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1134435:AC731 RS00550
gene id: 1134435:AC731_RS00550
uniprot id: A0A140ICU9
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS19085
gene id: 1134435:AC731_RS19085
uniprot id: A0A127KAE2
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS03105
gene id: 1134435:AC731_RS03105
uniprot id: A0A127KAH7
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

1134435:AC731 RS02860
gene id: 1134435:AC731_RS02860
uniprot id: A0A140IDZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

1134435:AC731 RS16145
gene id: 1134435:AC731_RS16145
uniprot id: A0A127K8P3
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

1134435:AC731 RS16230
gene id: 1134435:AC731_RS16230
uniprot id: A0A127K8R0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1134435:AC731 RS12355
gene id: 1134435:AC731_RS12355
uniprot id: A0A127K6S6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

1134435:AC731 RS02265
gene id: 1134435:AC731_RS02265
uniprot id: A0A140IDP7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

1134435:AC731 RS16785
gene id: 1134435:AC731_RS16785
uniprot id: A0A127K8Z2
names: Similarity
messages: Belongs to the PrpF family.

1134435:AC731 RS12780
gene id: 1134435:AC731_RS12780
uniprot id: A0A127K7T8
names: Similarity
messages: Belongs to the GSP E family.

1134435:AC731 RS13380
gene id: 1134435:AC731_RS13380
uniprot id: A0A127K841
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1134435:AC731 RS07460
gene id: 1134435:AC731_RS07460
uniprot id: A0A127K4B1
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

1134435:AC731 RS02430
gene id: 1134435:AC731_RS02430
uniprot id: A0A140IDS6
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

1134435:AC731 RS13940
gene id: 1134435:AC731_RS13940
uniprot id: A0A127K8C2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

1134435:AC731 RS00860
gene id: 1134435:AC731_RS00860
uniprot id: A0A140ID02
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

1134435:AC731 RS08365
gene id: 1134435:AC731_RS08365
uniprot id: A0A127K4T2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ureidoglycolate lyase family.
messages: Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source.
messages: Homodimer.

1134435:AC731 RS07905
gene id: 1134435:AC731_RS07905
uniprot id: A0A127K4I6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1134435:AC731 RS00150
gene id: 1134435:AC731_RS00150
uniprot id: A0A140ICM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1134435:AC731 RS14515
gene id: 1134435:AC731_RS14515
uniprot id: A0A127K7W5
names: Function
names: Subcellular Location Annotation
messages: Periplasm
messages: Transfers electrons from cytochrome c551 to cytochrome oxidase.

1134435:AC731 RS00035
gene id: 1134435:AC731_RS00035
uniprot id: A0A140ICK8
names: Cofactor
messages: Can also use Mn(2+) ion.

1134435:AC731 RS05215
gene id: 1134435:AC731_RS05215
uniprot id: A0A127K354
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

1134435:AC731 RS04740
gene id: 1134435:AC731_RS04740
uniprot id: A0A127KAS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1134435:AC731 RS02020
gene id: 1134435:AC731_RS02020
uniprot id: A0A140IDK4
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

1134435:AC731 RS06205
gene id: 1134435:AC731_RS06205
uniprot id: A0A127K3N5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

1134435:AC731 RS18215
gene id: 1134435:AC731_RS18215
uniprot id: A0A127K9Z7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1134435:AC731 RS18025
gene id: 1134435:AC731_RS18025
uniprot id: A0A127K9P3
names: Similarity
messages: Belongs to the MlaA family.

1134435:AC731 RS02040
gene id: 1134435:AC731_RS02040
uniprot id: A0A140IDK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

1134435:AC731 RS10205
gene id: 1134435:AC731_RS10205
uniprot id: A0A127K5S4
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

1134435:AC731 RS08825
gene id: 1134435:AC731_RS08825
uniprot id: A0A127K517
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1134435:AC731 RS00975
gene id: 1134435:AC731_RS00975
uniprot id: A0A140ID18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

1134435:AC731 RS16640
gene id: 1134435:AC731_RS16640
uniprot id: A0A127K8Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

1134435:AC731 RS14785
gene id: 1134435:AC731_RS14785
uniprot id: A0A127K839
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

1134435:AC731 RS07300
gene id: 1134435:AC731_RS07300
uniprot id: A0A127K489
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

1134435:AC731 RS11510
gene id: 1134435:AC731_RS11510
uniprot id: A0A127K6D1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

1134435:AC731 RS08620
gene id: 1134435:AC731_RS08620
uniprot id: A0A127K4Z1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1134435:AC731 RS16125
gene id: 1134435:AC731_RS16125
uniprot id: A0A127K8N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1134435:AC731 RS10210
gene id: 1134435:AC731_RS10210
uniprot id: A0A127K6M6
names: Similarity
messages: Belongs to the GARS family.

1134435:AC731 RS19360
gene id: 1134435:AC731_RS19360
uniprot id: A0A127KAC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1134435:AC731 RS04000
gene id: 1134435:AC731_RS04000
uniprot id: A0A140IEJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1134435:AC731 RS02560
gene id: 1134435:AC731_RS02560
uniprot id: A0A140IDU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

1134435:AC731 RS05160
gene id: 1134435:AC731_RS05160
uniprot id: A0A127K443
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

1134435:AC731 RS16705
gene id: 1134435:AC731_RS16705
uniprot id: A0A127K938
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

1134435:AC731 RS10670
gene id: 1134435:AC731_RS10670
uniprot id: A0A127K5X6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

1134435:AC731 RS11580
gene id: 1134435:AC731_RS11580
uniprot id: A0A127K6D3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

1134435:AC731 RS14115
gene id: 1134435:AC731_RS14115
uniprot id: A0A127K7M8
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

1134435:AC731 RS16150
gene id: 1134435:AC731_RS16150
uniprot id: A0A127K8N1
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS18150
gene id: 1134435:AC731_RS18150
uniprot id: A0A127K9R6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

1134435:AC731 RS18210
gene id: 1134435:AC731_RS18210
uniprot id: A0A127K9R7
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

1134435:AC731 RS01600
gene id: 1134435:AC731_RS01600
uniprot id: A0A127KAI3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1134435:AC731 RS04690
gene id: 1134435:AC731_RS04690
uniprot id: A0A127K2V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

1134435:AC731 RS07670
gene id: 1134435:AC731_RS07670
uniprot id: A0A127K4E5
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

1134435:AC731 RS12500
gene id: 1134435:AC731_RS12500
uniprot id: A0A127K6U8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

1134435:AC731 RS11615
gene id: 1134435:AC731_RS11615
uniprot id: A0A127K6F5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

1134435:AC731 RS07690
gene id: 1134435:AC731_RS07690
uniprot id: A0A127K4G4
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

1134435:AC731 RS18540
gene id: 1134435:AC731_RS18540
uniprot id: A0A127K9W7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

1134435:AC731 RS12395
gene id: 1134435:AC731_RS12395
uniprot id: A0A127K6U9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NosZ family.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytochrome c oxidase subunit 2 family.
messages: Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide.
messages: Periplasm

1134435:AC731 RS00585
gene id: 1134435:AC731_RS00585
uniprot id: A0A140ICV6
names: Subcellular Location Annotation
messages: Cytoplasm

1134435:AC731 RS03115
gene id: 1134435:AC731_RS03115
uniprot id: A0A127KAI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1134435:AC731 RS10445
gene id: 1134435:AC731_RS10445
uniprot id: A0A127K6Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

1134435:AC731 RS05240
gene id: 1134435:AC731_RS05240
uniprot id: A0A127K352
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

1134435:AC731 RS12600
gene id: 1134435:AC731_RS12600
uniprot id: A0A127K6X8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

1134435:AC731 RS17875
gene id: 1134435:AC731_RS17875
uniprot id: A0A127K9K7
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS17145
gene id: 1134435:AC731_RS17145
uniprot id: A0A127K965
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.

1134435:AC731 RS06785
gene id: 1134435:AC731_RS06785
uniprot id: A0A127K3Y5
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

1134435:AC731 RS02455
gene id: 1134435:AC731_RS02455
uniprot id: A0A140IDT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

1134435:AC731 RS07680
gene id: 1134435:AC731_RS07680
uniprot id: A0A127K4F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1134435:AC731 RS11565
gene id: 1134435:AC731_RS11565
uniprot id: A0A127K6E7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

1134435:AC731 RS17700
gene id: 1134435:AC731_RS17700
uniprot id: A0A127K9I9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1134435:AC731 RS16130
gene id: 1134435:AC731_RS16130
uniprot id: A0A127K8N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1134435:AC731 RS10075
gene id: 1134435:AC731_RS10075
uniprot id: A0A127K5N0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1134435:AC731 RS12895
gene id: 1134435:AC731_RS12895
uniprot id: A0A127K733
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1134435:AC731 RS15595
gene id: 1134435:AC731_RS15595
uniprot id: A0A127K8H9
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1134435:AC731 RS14210
gene id: 1134435:AC731_RS14210
uniprot id: A0A127K7Q9
names: Function
names: Similarity
messages: Belongs to the AMP nucleosidase family.
messages: Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.

1134435:AC731 RS14610
gene id: 1134435:AC731_RS14610
uniprot id: A0A127K837
names: Similarity
messages: Belongs to the hemerythrin family.

1134435:AC731 RS07775
gene id: 1134435:AC731_RS07775
uniprot id: A0A127K4F8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1134435:AC731 RS02085
gene id: 1134435:AC731_RS02085
uniprot id: A0A140IDL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

1134435:AC731 RS13970
gene id: 1134435:AC731_RS13970
uniprot id: A0A127K7J7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

1134435:AC731 RS18300
gene id: 1134435:AC731_RS18300
uniprot id: A0A127K9S7
names: Similarity
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.

1134435:AC731 RS13040
gene id: 1134435:AC731_RS13040
uniprot id: A0A127K757
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1134435:AC731 RS01685
gene id: 1134435:AC731_RS01685
uniprot id: A0A140IDE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1134435:AC731 RS03370
gene id: 1134435:AC731_RS03370
uniprot id: A0A140IE86
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

1134435:AC731 RS18340
gene id: 1134435:AC731_RS18340
uniprot id: A0A127K9X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1134435:AC731 RS13830
gene id: 1134435:AC731_RS13830
uniprot id: A0A127K8A7
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

1134435:AC731 RS18630
gene id: 1134435:AC731_RS18630
uniprot id: A0A127KA13
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

1134435:AC731 RS09955
gene id: 1134435:AC731_RS09955
uniprot id: A0A127K5K9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

1134435:AC731 RS11080
gene id: 1134435:AC731_RS11080
uniprot id: A0A127K643
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS01740
gene id: 1134435:AC731_RS01740
uniprot id: A0A140IDF3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

1134435:AC731 RS18950
gene id: 1134435:AC731_RS18950
uniprot id: A0A127KA60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

1134435:AC731 RS12640
gene id: 1134435:AC731_RS12640
uniprot id: A0A127K6Z9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

1134435:AC731 RS19230
gene id: 1134435:AC731_RS19230
uniprot id: A0A127KA86
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS17775
gene id: 1134435:AC731_RS17775
uniprot id: A0A127K9J3
names: Subcellular Location Annotation
messages: Cell inner membrane

1134435:AC731 RS10915
gene id: 1134435:AC731_RS10915
uniprot id: A0A127K658
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1134435:AC731 RS01130
gene id: 1134435:AC731_RS01130
uniprot id: A0A140ID46
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of five rings (E,L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

1134435:AC731 RS08815
gene id: 1134435:AC731_RS08815
uniprot id: A0A127K511
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1134435:AC731 RS17915
gene id: 1134435:AC731_RS17915
uniprot id: A0A127KB67
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1134435:AC731 RS05200
gene id: 1134435:AC731_RS05200
uniprot id: A0A127K347
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

1134435:AC731 RS06060
gene id: 1134435:AC731_RS06060
uniprot id: A0A127K3K7
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

1134435:AC731 RS11530
gene id: 1134435:AC731_RS11530
uniprot id: A0A127K6C6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

1134435:AC731 RS14065
gene id: 1134435:AC731_RS14065
uniprot id: A0A127K7M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

1134435:AC731 RS17285
gene id: 1134435:AC731_RS17285
uniprot id: A0A127K9E4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1134435:AC731 RS07510
gene id: 1134435:AC731_RS07510
uniprot id: A0A127K4C1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

1134435:AC731 RS12085
gene id: 1134435:AC731_RS12085
uniprot id: A0A127K6M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1134435:AC731 RS09800
gene id: 1134435:AC731_RS09800
uniprot id: A0A127K5I8
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

1134435:AC731 RS09640
gene id: 1134435:AC731_RS09640
uniprot id: A0A127KAR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

1134435:AC731 RS17375
gene id: 1134435:AC731_RS17375
uniprot id: A0A127K9D1
names: Similarity
messages: Belongs to the asparaginase 1 family.

1134435:AC731 RS00080
gene id: 1134435:AC731_RS00080
uniprot id: A0A127KAB8
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

1134435:AC731 RS09325
gene id: 1134435:AC731_RS09325
uniprot id: A0A127K653
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0761 family.
messages: Cell membrane
messages: Membrane

1134435:AC731 RS04465
gene id: 1134435:AC731_RS04465
uniprot id: A0A127K2S9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

1134435:AC731 RS02070
gene id: 1134435:AC731_RS02070
uniprot id: A0A140IDL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

1134435:AC731 RS04080
gene id: 1134435:AC731_RS04080
uniprot id: A0A140IEL2
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

1134435:AC731 RS08470
gene id: 1134435:AC731_RS08470
uniprot id: A0A127K4U0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1134435:AC731 RS12810
gene id: 1134435:AC731_RS12810
uniprot id: A0A127K6Z8
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1134435:AC731 RS09595
gene id: 1134435:AC731_RS09595
uniprot id: A0A127K5F5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1134435:AC731 RS17520
gene id: 1134435:AC731_RS17520
uniprot id: A0A127K9D9
names: Similarity
messages: Belongs to the peptidase S13 family.

1134435:AC731 RS05210
gene id: 1134435:AC731_RS05210
uniprot id: A0A127K452
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

1134435:AC731 RS10545
gene id: 1134435:AC731_RS10545
uniprot id: A0A127K5W3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS04545
gene id: 1134435:AC731_RS04545
uniprot id: A0A127K2T4
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1134435:AC731 RS18735
gene id: 1134435:AC731_RS18735
uniprot id: A0A127KA46
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS12745
gene id: 1134435:AC731_RS12745
uniprot id: A0A127K709
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

1134435:AC731 RS01095
gene id: 1134435:AC731_RS01095
uniprot id: A0A140ID39
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

1134435:AC731 RS15760
gene id: 1134435:AC731_RS15760
uniprot id: A0A127K8L6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1134435:AC731 RS03625
gene id: 1134435:AC731_RS03625
uniprot id: A0A140IED1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane
messages: Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.

1134435:AC731 RS14755
gene id: 1134435:AC731_RS14755
uniprot id: A0A127K814
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS09795
gene id: 1134435:AC731_RS09795
uniprot id: A0A127K5J0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

1134435:AC731 RS10630
gene id: 1134435:AC731_RS10630
uniprot id: A0A127K5Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

1134435:AC731 RS14235
gene id: 1134435:AC731_RS14235
uniprot id: A0A127K7T4
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1134435:AC731 RS19000
gene id: 1134435:AC731_RS19000
uniprot id: A0A127KA71
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS01795
gene id: 1134435:AC731_RS01795
uniprot id: A0A140IDG4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS01350
gene id: 1134435:AC731_RS01350
uniprot id: A0A140ID86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1134435:AC731 RS16050
gene id: 1134435:AC731_RS16050
uniprot id: A0A127K8N2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1134435:AC731 RS13235
gene id: 1134435:AC731_RS13235
uniprot id: A0A127K772
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

1134435:AC731 RS02530
gene id: 1134435:AC731_RS02530
uniprot id: A0A140IDU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine.
messages: Cytoplasm
messages: Homodimer.

1134435:AC731 RS03010
gene id: 1134435:AC731_RS03010
uniprot id: A0A140IE27
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1134435:AC731 RS05120
gene id: 1134435:AC731_RS05120
uniprot id: A0A127K333
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0114 family.
messages: Cell membrane
messages: Membrane

1134435:AC731 RS15035
gene id: 1134435:AC731_RS15035
uniprot id: A0A127K856
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

1134435:AC731 RS10840
gene id: 1134435:AC731_RS10840
uniprot id: A0A127K611
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

1134435:AC731 RS09365
gene id: 1134435:AC731_RS09365
uniprot id: A0A127K5A8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

1134435:AC731 RS12260
gene id: 1134435:AC731_RS12260
uniprot id: A0A127K6P4
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS00660
gene id: 1134435:AC731_RS00660
uniprot id: A0A140ICW4
names: Similarity
messages: Belongs to the thioredoxin family.

1134435:AC731 RS00310
gene id: 1134435:AC731_RS00310
uniprot id: A0A140ICQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1134435:AC731 RS07480
gene id: 1134435:AC731_RS07480
uniprot id: A0A127K4B9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

1134435:AC731 RS16485
gene id: 1134435:AC731_RS16485
uniprot id: A0A127K923
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

1134435:AC731 RS14630
gene id: 1134435:AC731_RS14630
uniprot id: A0A127K7X0
names: PTM
messages: Binds 1 heme group per subunit.

1134435:AC731 RS06700
gene id: 1134435:AC731_RS06700
uniprot id: A0A127K3X5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

1134435:AC731 RS17910
gene id: 1134435:AC731_RS17910
uniprot id: A0A127K9M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

1134435:AC731 RS07745
gene id: 1134435:AC731_RS07745
uniprot id: A0A127K4H5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhD family.
messages: Cytoplasm
messages: Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Homodimer; disulfide-linked. Forms a heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The C-terminal region contains a putative helix-turn-helix (HTH) motif, suggesting that this region may bind DNA.

1134435:AC731 RS15700
gene id: 1134435:AC731_RS15700
uniprot id: A0A127K8F6
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS18620
gene id: 1134435:AC731_RS18620
uniprot id: A0A127KAT8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

1134435:AC731 RS11065
gene id: 1134435:AC731_RS11065
uniprot id: A0A127K639
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1134435:AC731 RS16120
gene id: 1134435:AC731_RS16120
uniprot id: A0A127K9H6
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

1134435:AC731 RS00545
gene id: 1134435:AC731_RS00545
uniprot id: A0A140ICU8
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS00070
gene id: 1134435:AC731_RS00070
uniprot id: A0A140ICL4
names: Similarity
messages: Belongs to the UPF0758 family.

1134435:AC731 RS17325
gene id: 1134435:AC731_RS17325
uniprot id: A0A127K993
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS13350
gene id: 1134435:AC731_RS13350
uniprot id: A0A127K796
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS15840
gene id: 1134435:AC731_RS15840
uniprot id: A0A127K8K8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1134435:AC731 RS03965
gene id: 1134435:AC731_RS03965
uniprot id: A0A140IEJ2
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

1134435:AC731 RS17935
gene id: 1134435:AC731_RS17935
uniprot id: A0A127K9M7
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

1134435:AC731 RS14930
gene id: 1134435:AC731_RS14930
uniprot id: A0A127K836
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

1134435:AC731 RS16875
gene id: 1134435:AC731_RS16875
uniprot id: A0A127K924
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

1134435:AC731 RS00515
gene id: 1134435:AC731_RS00515
uniprot id: A0A140ICU2
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS01210
gene id: 1134435:AC731_RS01210
uniprot id: A0A140ID61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

1134435:AC731 RS05645
gene id: 1134435:AC731_RS05645
uniprot id: A0A127K3C3
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

1134435:AC731 RS11480
gene id: 1134435:AC731_RS11480
uniprot id: A0A127K6B6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

1134435:AC731 RS18535
gene id: 1134435:AC731_RS18535
uniprot id: A0A127K9Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

1134435:AC731 RS15505
gene id: 1134435:AC731_RS15505
uniprot id: A0A127K8C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

1134435:AC731 RS11505
gene id: 1134435:AC731_RS11505
uniprot id: A0A127K6C5
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

1134435:AC731 RS16195
gene id: 1134435:AC731_RS16195
uniprot id: A0A127K8R9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

1134435:AC731 RS10250
gene id: 1134435:AC731_RS10250
uniprot id: A0A127K5R2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

1134435:AC731 RS16690
gene id: 1134435:AC731_RS16690
uniprot id: A0A127K900
names: Function
names: Similarity
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.

1134435:AC731 RS12105
gene id: 1134435:AC731_RS12105
uniprot id: A0A127K6L7
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

1134435:AC731 RS09920
gene id: 1134435:AC731_RS09920
uniprot id: A0A127K5K6
names: Similarity
messages: Belongs to the ALAD family.

1134435:AC731 RS07250
gene id: 1134435:AC731_RS07250
uniprot id: A0A127K471
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

1134435:AC731 RS00175
gene id: 1134435:AC731_RS00175
uniprot id: A0A140ICN4
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS11780
gene id: 1134435:AC731_RS11780
uniprot id: A0A127K6L3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1134435:AC731 RS03990
gene id: 1134435:AC731_RS03990
uniprot id: A0A140IEJ7
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS13260
gene id: 1134435:AC731_RS13260
uniprot id: A0A127K7D0
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

1134435:AC731 RS12615
gene id: 1134435:AC731_RS12615
uniprot id: A0A127K6X2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

1134435:AC731 RS08475
gene id: 1134435:AC731_RS08475
uniprot id: A0A127K4U4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1134435:AC731 RS18845
gene id: 1134435:AC731_RS18845
uniprot id: A0A127KAA3
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

1134435:AC731 RS00710
gene id: 1134435:AC731_RS00710
uniprot id: A0A140ICX4
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

1134435:AC731 RS17370
gene id: 1134435:AC731_RS17370
uniprot id: A0A127K9B1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1134435:AC731 RS14390
gene id: 1134435:AC731_RS14390
uniprot id: A0A127K7S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

1134435:AC731 RS10995
gene id: 1134435:AC731_RS10995
uniprot id: A0A127K6Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1134435:AC731 RS07710
gene id: 1134435:AC731_RS07710
uniprot id: A0A127K4E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheZ family.
messages: Cytoplasm

1134435:AC731 RS17585
gene id: 1134435:AC731_RS17585
uniprot id: A0A127K9G9
names: Similarity
messages: Belongs to the glutamate synthase family.

1134435:AC731 RS17680
gene id: 1134435:AC731_RS17680
uniprot id: A0A127K9H0
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Member of a two-component regulatory system.

1134435:AC731 RS00720
gene id: 1134435:AC731_RS00720
uniprot id: A0A140ICX6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

1134435:AC731 RS01220
gene id: 1134435:AC731_RS01220
uniprot id: A0A140ID63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

1134435:AC731 RS16780
gene id: 1134435:AC731_RS16780
uniprot id: A0A127K926
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1134435:AC731 RS16765
gene id: 1134435:AC731_RS16765
uniprot id: A0A127K9U5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1134435:AC731 RS12765
gene id: 1134435:AC731_RS12765
uniprot id: A0A127K744
names: Similarity
messages: Belongs to the YggT family.

1134435:AC731 RS07665
gene id: 1134435:AC731_RS07665
uniprot id: A0A127K4E6
names: Similarity
messages: Belongs to the UPF0434 family.

1134435:AC731 RS04900
gene id: 1134435:AC731_RS04900
uniprot id: A0A127K3Z2
names: Similarity
messages: Belongs to the HisA/HisF family.

1134435:AC731 RS18200
gene id: 1134435:AC731_RS18200
uniprot id: A0A127K9Q2
names: Similarity
messages: Belongs to the TrpC family.

1134435:AC731 RS17070
gene id: 1134435:AC731_RS17070
uniprot id: A0A127K966
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

1134435:AC731 RS13670
gene id: 1134435:AC731_RS13670
uniprot id: A0A127K7E5
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

1134435:AC731 RS01265
gene id: 1134435:AC731_RS01265
uniprot id: A0A127KAE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility.
messages: Bacterial flagellum basal body
messages: Belongs to the YcgR family.
messages: Monomer. Interacts with the flagellar basal bodies.

1134435:AC731 RS08680
gene id: 1134435:AC731_RS08680
uniprot id: A0A127K4X8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

1134435:AC731 RS14530
gene id: 1134435:AC731_RS14530
uniprot id: A0A127KB31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

1134435:AC731 RS16405
gene id: 1134435:AC731_RS16405
uniprot id: A0A127K8T1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1134435:AC731 RS02025
gene id: 1134435:AC731_RS02025
uniprot id: A0A140IDK5
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS18900
gene id: 1134435:AC731_RS18900
uniprot id: A0A127KA43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

1134435:AC731 RS12785
gene id: 1134435:AC731_RS12785
uniprot id: A0A127K6Z7
names: Similarity
messages: Belongs to the GSP E family.

1134435:AC731 RS01125
gene id: 1134435:AC731_RS01125
uniprot id: A0A140ID45
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

1134435:AC731 RS19265
gene id: 1134435:AC731_RS19265
uniprot id: A0A127KAH0
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

1134435:AC731 RS03860
gene id: 1134435:AC731_RS03860
uniprot id: A0A140IEH3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

1134435:AC731 RS02660
gene id: 1134435:AC731_RS02660
uniprot id: A0A140IDW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1134435:AC731 RS11880
gene id: 1134435:AC731_RS11880
uniprot id: A0A127K6N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1134435:AC731 RS09710
gene id: 1134435:AC731_RS09710
uniprot id: A0A127K6C4
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

1134435:AC731 RS13215
gene id: 1134435:AC731_RS13215
uniprot id: A0A127K792
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

1134435:AC731 RS17440
gene id: 1134435:AC731_RS17440
uniprot id: A0A127K9C6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1134435:AC731 RS15825
gene id: 1134435:AC731_RS15825
uniprot id: A0A127K9C8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1134435:AC731 RS15460
gene id: 1134435:AC731_RS15460
uniprot id: A0A127K8I3
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

1134435:AC731 RS13615
gene id: 1134435:AC731_RS13615
uniprot id: A0A127K7K0
names: Similarity
messages: Belongs to the HypE family.

1134435:AC731 RS03680
gene id: 1134435:AC731_RS03680
uniprot id: A0A140IEE1
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

1134435:AC731 RS14145
gene id: 1134435:AC731_RS14145
uniprot id: A0A127K7N5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1134435:AC731 RS15080
gene id: 1134435:AC731_RS15080
uniprot id: A0A127K853
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

1134435:AC731 RS03730
gene id: 1134435:AC731_RS03730
uniprot id: A0A140IEF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

1134435:AC731 RS01370
gene id: 1134435:AC731_RS01370
uniprot id: A0A140ID90
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1134435:AC731 RS04955
gene id: 1134435:AC731_RS04955
uniprot id: A0A127K306
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1134435:AC731 RS17460
gene id: 1134435:AC731_RS17460
uniprot id: A0A127KA78
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1134435:AC731 RS15920
gene id: 1134435:AC731_RS15920
uniprot id: A0A127K8J2
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS15705
gene id: 1134435:AC731_RS15705
uniprot id: A0A127K8N6
names: Similarity
messages: Belongs to the leucine-binding protein family.

1134435:AC731 RS18080
gene id: 1134435:AC731_RS18080
uniprot id: A0A127K9P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

1134435:AC731 RS04140
gene id: 1134435:AC731_RS04140
uniprot id: A0A140IEM2
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

1134435:AC731 RS17250
gene id: 1134435:AC731_RS17250
uniprot id: A0A127K989
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

1134435:AC731 RS14085
gene id: 1134435:AC731_RS14085
uniprot id: A0A127K7N6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

1134435:AC731 RS18235
gene id: 1134435:AC731_RS18235
uniprot id: A0A127K9S0
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

1134435:AC731 RS00685
gene id: 1134435:AC731_RS00685
uniprot id: A0A140ICW9
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Dimer of large and small chains.

1134435:AC731 RS13195
gene id: 1134435:AC731_RS13195
uniprot id: A0A127K766
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

1134435:AC731 RS06710
gene id: 1134435:AC731_RS06710
uniprot id: A0A127K3X4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

1134435:AC731 RS03000
gene id: 1134435:AC731_RS03000
uniprot id: A0A140IE25
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS07780
gene id: 1134435:AC731_RS07780
uniprot id: A0A127K4G6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1134435:AC731 RS12460
gene id: 1134435:AC731_RS12460
uniprot id: A0A127KAX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsB sub-subfamily.
messages: Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane

1134435:AC731 RS00835
gene id: 1134435:AC731_RS00835
uniprot id: A0A140ICZ8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS12155
gene id: 1134435:AC731_RS12155
uniprot id: A0A127K6P2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

1134435:AC731 RS11090
gene id: 1134435:AC731_RS11090
uniprot id: A0A127K665
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

1134435:AC731 RS00555
gene id: 1134435:AC731_RS00555
uniprot id: A0A140ICV0
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS00755
gene id: 1134435:AC731_RS00755
uniprot id: A0A140ICY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

1134435:AC731 RS02875
gene id: 1134435:AC731_RS02875
uniprot id: A0A140IE01
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1134435:AC731 RS04665
gene id: 1134435:AC731_RS04665
uniprot id: A0A127K2V8
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

1134435:AC731 RS00065
gene id: 1134435:AC731_RS00065
uniprot id: A0A140ICL3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

1134435:AC731 RS11575
gene id: 1134435:AC731_RS11575
uniprot id: A0A127K6D7
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

1134435:AC731 RS19180
gene id: 1134435:AC731_RS19180
uniprot id: A0A127KAA1
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

1134435:AC731 RS06955
gene id: 1134435:AC731_RS06955
uniprot id: A0A127K411
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1134435:AC731 RS08485
gene id: 1134435:AC731_RS08485
uniprot id: A0A127K4U6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1134435:AC731 RS17530
gene id: 1134435:AC731_RS17530
uniprot id: A0A127K9F8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

1134435:AC731 RS02665
gene id: 1134435:AC731_RS02665
uniprot id: A0A140IDW4
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1134435:AC731 RS13985
gene id: 1134435:AC731_RS13985
uniprot id: A0A127K7J8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

1134435:AC731 RS06845
gene id: 1134435:AC731_RS06845
uniprot id: A0A127K3Z3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

1134435:AC731 RS08445
gene id: 1134435:AC731_RS08445
uniprot id: A0A127K5P6
names: Similarity
messages: Belongs to the pyruvate kinase family.

1134435:AC731 RS12060
gene id: 1134435:AC731_RS12060
uniprot id: A0A127K6N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1134435:AC731 RS17040
gene id: 1134435:AC731_RS17040
uniprot id: A0A127K972
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1134435:AC731 RS07630
gene id: 1134435:AC731_RS07630
uniprot id: A0A127K4F4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1134435:AC731 RS17045
gene id: 1134435:AC731_RS17045
uniprot id: A0A127K944
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

1134435:AC731 RS00510
gene id: 1134435:AC731_RS00510
uniprot id: A0A127KAG2
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

1134435:AC731 RS10300
gene id: 1134435:AC731_RS10300
uniprot id: A0A127K5R7
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

1134435:AC731 RS10450
gene id: 1134435:AC731_RS10450
uniprot id: A0A127K5V5
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS07860
gene id: 1134435:AC731_RS07860
uniprot id: A0A127K4I7
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Member of a two-component regulatory system.

1134435:AC731 RS17570
gene id: 1134435:AC731_RS17570
uniprot id: A0A127KA96
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1134435:AC731 RS20150
gene id: 1134435:AC731_RS20150
uniprot id: A0A127K4Q8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1134435:AC731 RS04255
gene id: 1134435:AC731_RS04255
uniprot id: A0A140IEP0
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

1134435:AC731 RS17245
gene id: 1134435:AC731_RS17245
uniprot id: A0A127KB59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

1134435:AC731 RS09305
gene id: 1134435:AC731_RS09305
uniprot id: A0A127K597
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1134435:AC731 RS06920
gene id: 1134435:AC731_RS06920
uniprot id: A0A127K4Y5
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

1134435:AC731 RS12680
gene id: 1134435:AC731_RS12680
uniprot id: A0A127K6X9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1134435:AC731 RS14420
gene id: 1134435:AC731_RS14420
uniprot id: A0A127K7T5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

1134435:AC731 RS14070
gene id: 1134435:AC731_RS14070
uniprot id: A0A127K7L3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

1134435:AC731 RS18880
gene id: 1134435:AC731_RS18880
uniprot id: A0A127KA30
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

1134435:AC731 RS04920
gene id: 1134435:AC731_RS04920
uniprot id: A0A127K2Z9
names: Similarity
messages: Belongs to the FwdC/FmdC family.

1134435:AC731 RS08775
gene id: 1134435:AC731_RS08775
uniprot id: A0A127K519
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS00690
gene id: 1134435:AC731_RS00690
uniprot id: A0A140ICX0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

1134435:AC731 RS02100
gene id: 1134435:AC731_RS02100
uniprot id: A0A140IDL8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1134435:AC731 RS09770
gene id: 1134435:AC731_RS09770
uniprot id: A0A127K6E0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

1134435:AC731 RS16960
gene id: 1134435:AC731_RS16960
uniprot id: A0A127K985
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0065 (bug) family.
messages: Periplasm

1134435:AC731 RS04415
gene id: 1134435:AC731_RS04415
uniprot id: A0A127K3R7
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

1134435:AC731 RS07765
gene id: 1134435:AC731_RS07765
uniprot id: A0A127K4G3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1134435:AC731 RS15200
gene id: 1134435:AC731_RS15200
uniprot id: A0A127K908
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

1134435:AC731 RS15730
gene id: 1134435:AC731_RS15730
uniprot id: A0A127K8G9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

1134435:AC731 RS18965
gene id: 1134435:AC731_RS18965
uniprot id: A0A127KA48
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1134435:AC731 RS16665
gene id: 1134435:AC731_RS16665
uniprot id: A0A127K9S4
names: Function
names: Similarity
messages: Belongs to the UbiT family.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Likely functions as an accessory factor.

1134435:AC731 RS14375
gene id: 1134435:AC731_RS14375
uniprot id: A0A127K7T9
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

1134435:AC731 RS05840
gene id: 1134435:AC731_RS05840
uniprot id: A0A127K3G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

1134435:AC731 RS19035
gene id: 1134435:AC731_RS19035
uniprot id: A0A127KA95
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

1134435:AC731 RS18825
gene id: 1134435:AC731_RS18825
uniprot id: A0A127KA39
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

1134435:AC731 RS17895
gene id: 1134435:AC731_RS17895
uniprot id: A0A127K9L5
names: Similarity
messages: Belongs to the PhoH family.

1134435:AC731 RS06095
gene id: 1134435:AC731_RS06095
uniprot id: A0A127K3L2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

1134435:AC731 RS02550
gene id: 1134435:AC731_RS02550
uniprot id: A0A140IDU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1134435:AC731 RS18550
gene id: 1134435:AC731_RS18550
uniprot id: A0A127K9X5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1134435:AC731 RS00665
gene id: 1134435:AC731_RS00665
uniprot id: A0A140ICW5
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

1134435:AC731 RS02555
gene id: 1134435:AC731_RS02555
uniprot id: A0A140IDU5
names: Function
names: Similarity
messages: Belongs to the SsuD family.
messages: Catalyzes the desulfonation of aliphatic sulfonates.

1134435:AC731 RS11625
gene id: 1134435:AC731_RS11625
uniprot id: A0A127K6E8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1134435:AC731 RS13570
gene id: 1134435:AC731_RS13570
uniprot id: A0A127K870
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

1134435:AC731 RS11170
gene id: 1134435:AC731_RS11170
uniprot id: A0A127K6A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

1134435:AC731 RS03630
gene id: 1134435:AC731_RS03630
uniprot id: A0A140IED2
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

1134435:AC731 RS17740
gene id: 1134435:AC731_RS17740
uniprot id: A0A127K9J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

1134435:AC731 RS00740
gene id: 1134435:AC731_RS00740
uniprot id: A0A140ICX9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS16930
gene id: 1134435:AC731_RS16930
uniprot id: A0A127K930
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS11620
gene id: 1134435:AC731_RS11620
uniprot id: A0A127K797
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

1134435:AC731 RS09300
gene id: 1134435:AC731_RS09300
uniprot id: A0A127K591
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS12920
gene id: 1134435:AC731_RS12920
uniprot id: A0A127K737
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS11785
gene id: 1134435:AC731_RS11785
uniprot id: A0A127K6I3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS14055
gene id: 1134435:AC731_RS14055
uniprot id: A0A127K7N0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

1134435:AC731 RS05040
gene id: 1134435:AC731_RS05040
uniprot id: A0A127K312
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1134435:AC731 RS17640
gene id: 1134435:AC731_RS17640
uniprot id: A0A127K9F5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

1134435:AC731 RS13955
gene id: 1134435:AC731_RS13955
uniprot id: A0A127K7L4
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

1134435:AC731 RS08515
gene id: 1134435:AC731_RS08515
uniprot id: A0A127K4W5
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

1134435:AC731 RS14325
gene id: 1134435:AC731_RS14325
uniprot id: A0A127K7R7
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

1134435:AC731 RS01160
gene id: 1134435:AC731_RS01160
uniprot id: A0A140ID52
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

1134435:AC731 RS11180
gene id: 1134435:AC731_RS11180
uniprot id: A0A127K676
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1134435:AC731 RS19310
gene id: 1134435:AC731_RS19310
uniprot id: A0A127KAB4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

1134435:AC731 RS10550
gene id: 1134435:AC731_RS10550
uniprot id: A0A127K5V2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

1134435:AC731 RS17135
gene id: 1134435:AC731_RS17135
uniprot id: A0A127K970
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

1134435:AC731 RS13150
gene id: 1134435:AC731_RS13150
uniprot id: A0A127K779
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS03030
gene id: 1134435:AC731_RS03030
uniprot id: A0A140IE29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

1134435:AC731 RS00245
gene id: 1134435:AC731_RS00245
uniprot id: A0A140ICP6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

1134435:AC731 RS20380
gene id: 1134435:AC731_RS20380
uniprot id: A0A127K8X6
names: Similarity
messages: Belongs to the arginase family.

1134435:AC731 RS11490
gene id: 1134435:AC731_RS11490
uniprot id: A0A127K6F4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1134435:AC731 RS16095
gene id: 1134435:AC731_RS16095
uniprot id: A0A127KB13
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

1134435:AC731 RS04145
gene id: 1134435:AC731_RS04145
uniprot id: A0A140IEM3
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

1134435:AC731 RS18375
gene id: 1134435:AC731_RS18375
uniprot id: A0A127K9V7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

1134435:AC731 RS00815
gene id: 1134435:AC731_RS00815
uniprot id: A0A140ICZ4
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

1134435:AC731 RS06370
gene id: 1134435:AC731_RS06370
uniprot id: A0A127K3R6
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS04085
gene id: 1134435:AC731_RS04085
uniprot id: A0A140IEL3
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

1134435:AC731 RS10530
gene id: 1134435:AC731_RS10530
uniprot id: A0A127K5V9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

1134435:AC731 RS19195
gene id: 1134435:AC731_RS19195
uniprot id: A0A127KA90
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1134435:AC731 RS19315
gene id: 1134435:AC731_RS19315
uniprot id: A0A127KAA7
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

1134435:AC731 RS17230
gene id: 1134435:AC731_RS17230
uniprot id: A0A127K994
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

1134435:AC731 RS01985
gene id: 1134435:AC731_RS01985
uniprot id: A0A140IDJ7
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

1134435:AC731 RS02435
gene id: 1134435:AC731_RS02435
uniprot id: A0A140IDS7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1134435:AC731 RS12270
gene id: 1134435:AC731_RS12270
uniprot id: A0A127K6R7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

1134435:AC731 RS11630
gene id: 1134435:AC731_RS11630
uniprot id: A0A127K6E2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

1134435:AC731 RS06160
gene id: 1134435:AC731_RS06160
uniprot id: A0A127K3M7
names: Similarity
messages: Belongs to the PhoH family.

1134435:AC731 RS17035
gene id: 1134435:AC731_RS17035
uniprot id: A0A127K950
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

1134435:AC731 RS14600
gene id: 1134435:AC731_RS14600
uniprot id: A0A127K7X8
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

1134435:AC731 RS01515
gene id: 1134435:AC731_RS01515
uniprot id: A0A140IDB6
names: Similarity
messages: Belongs to the pirin family.

1134435:AC731 RS01615
gene id: 1134435:AC731_RS01615
uniprot id: A0A140IDD1
names: Similarity
messages: Belongs to the GST superfamily.

1134435:AC731 RS04295
gene id: 1134435:AC731_RS04295
uniprot id: A0A140IEP6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1134435:AC731 RS08020
gene id: 1134435:AC731_RS08020
uniprot id: A0A127KAQ2
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

1134435:AC731 RS03890
gene id: 1134435:AC731_RS03890
uniprot id: A0A140IEH9
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

1134435:AC731 RS13185
gene id: 1134435:AC731_RS13185
uniprot id: A0A127K762
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1134435:AC731 RS10965
gene id: 1134435:AC731_RS10965
uniprot id: A0A127K624
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1134435:AC731 RS07740
gene id: 1134435:AC731_RS07740
uniprot id: A0A127K4G7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhC family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.

1134435:AC731 RS15960
gene id: 1134435:AC731_RS15960
uniprot id: A0A127K8M9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1134435:AC731 RS07310
gene id: 1134435:AC731_RS07310
uniprot id: A0A127K480
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

1134435:AC731 RS00745
gene id: 1134435:AC731_RS00745
uniprot id: A0A140ICY0
names: Similarity
messages: Belongs to the TrpF family.

1134435:AC731 RS06085
gene id: 1134435:AC731_RS06085
uniprot id: A0A127K3K1
names: Similarity
messages: Belongs to the UPF0229 family.

1134435:AC731 RS10140
gene id: 1134435:AC731_RS10140
uniprot id: A0A127K5Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

1134435:AC731 RS05050
gene id: 1134435:AC731_RS05050
uniprot id: A0A127K320
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

1134435:AC731 RS07645
gene id: 1134435:AC731_RS07645
uniprot id: A0A127KAQ8
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS11860
gene id: 1134435:AC731_RS11860
uniprot id: A0A127K6J0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

1134435:AC731 RS16905
gene id: 1134435:AC731_RS16905
uniprot id: A0A127K9A6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1134435:AC731 RS14315
gene id: 1134435:AC731_RS14315
uniprot id: A0A127K7R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1134435:AC731 RS02305
gene id: 1134435:AC731_RS02305
uniprot id: A0A140IDQ5
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

1134435:AC731 RS17665
gene id: 1134435:AC731_RS17665
uniprot id: A0A127K9L1
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1134435:AC731 RS02210
gene id: 1134435:AC731_RS02210
uniprot id: A0A127KAF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

1134435:AC731 RS02990
gene id: 1134435:AC731_RS02990
uniprot id: A0A140IE23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

1134435:AC731 RS02030
gene id: 1134435:AC731_RS02030
uniprot id: A0A140IDK6
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

1134435:AC731 RS17495
gene id: 1134435:AC731_RS17495
uniprot id: A0A127K9D6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

1134435:AC731 RS02390
gene id: 1134435:AC731_RS02390
uniprot id: A0A140IDR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane

1134435:AC731 RS02160
gene id: 1134435:AC731_RS02160
uniprot id: A0A140IDN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1134435:AC731 RS03975
gene id: 1134435:AC731_RS03975
uniprot id: A0A140IEJ4
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

1134435:AC731 RS11650
gene id: 1134435:AC731_RS11650
uniprot id: A0A127K6G7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1134435:AC731 RS08310
gene id: 1134435:AC731_RS08310
uniprot id: A0A127K4S2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1134435:AC731 RS00855
gene id: 1134435:AC731_RS00855
uniprot id: A0A140ID01
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1134435:AC731 RS14090
gene id: 1134435:AC731_RS14090
uniprot id: A0A127K8F2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

1134435:AC731 RS18810
gene id: 1134435:AC731_RS18810
uniprot id: A0A127KA14
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

1134435:AC731 RS00350
gene id: 1134435:AC731_RS00350
uniprot id: A0A140ICR5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1134435:AC731 RS00410
gene id: 1134435:AC731_RS00410
uniprot id: A0A140ICS5
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS02290
gene id: 1134435:AC731_RS02290
uniprot id: A0A140IDQ2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1134435:AC731 RS11600
gene id: 1134435:AC731_RS11600
uniprot id: A0A127K6F7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

1134435:AC731 RS06110
gene id: 1134435:AC731_RS06110
uniprot id: A0A127K3L5
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

1134435:AC731 RS18130
gene id: 1134435:AC731_RS18130
uniprot id: A0A127K9Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

1134435:AC731 RS18490
gene id: 1134435:AC731_RS18490
uniprot id: A0A127K9X3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

1134435:AC731 RS03810
gene id: 1134435:AC731_RS03810
uniprot id: A0A127KAI8
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

1134435:AC731 RS18795
gene id: 1134435:AC731_RS18795
uniprot id: A0A127KA56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1134435:AC731 RS00775
gene id: 1134435:AC731_RS00775
uniprot id: A0A140ICY6
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS13895
gene id: 1134435:AC731_RS13895
uniprot id: A0A127K7J0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1134435:AC731 RS18705
gene id: 1134435:AC731_RS18705
uniprot id: A0A127KA00
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1134435:AC731 RS09340
gene id: 1134435:AC731_RS09340
uniprot id: A0A127K5A0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

1134435:AC731 RS05250
gene id: 1134435:AC731_RS05250
uniprot id: A0A127K353
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1134435:AC731 RS02080
gene id: 1134435:AC731_RS02080
uniprot id: A0A140IDL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

1134435:AC731 RS01360
gene id: 1134435:AC731_RS01360
uniprot id: A0A140ID88
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1134435:AC731 RS13625
gene id: 1134435:AC731_RS13625
uniprot id: A0A127KB21
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

1134435:AC731 RS02315
gene id: 1134435:AC731_RS02315
uniprot id: A0A140IDQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

1134435:AC731 RS18095
gene id: 1134435:AC731_RS18095
uniprot id: A0A127K9N3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

1134435:AC731 RS14730
gene id: 1134435:AC731_RS14730
uniprot id: A0A127K805
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

1134435:AC731 RS04845
gene id: 1134435:AC731_RS04845
uniprot id: A0A127K2X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCH family.
messages: Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl-H(4)MPT.
messages: Cytoplasm

1134435:AC731 RS05825
gene id: 1134435:AC731_RS05825
uniprot id: A0A127K3G6
names: Similarity
messages: Belongs to the ModE family.

1134435:AC731 RS12735
gene id: 1134435:AC731_RS12735
uniprot id: A0A127K6Y6
names: Similarity
messages: Belongs to the DNA photolyase family.

1134435:AC731 RS18115
gene id: 1134435:AC731_RS18115
uniprot id: A0A127K9U1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1134435:AC731 RS13415
gene id: 1134435:AC731_RS13415
uniprot id: A0A127K7A7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1134435:AC731 RS09575
gene id: 1134435:AC731_RS09575
uniprot id: A0A127K5F4
names: Similarity
messages: Belongs to the AOR/FOR family.

1134435:AC731 RS00565
gene id: 1134435:AC731_RS00565
uniprot id: A0A140ICV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1134435:AC731 RS07760
gene id: 1134435:AC731_RS07760
uniprot id: A0A127K4H0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1134435:AC731 RS17605
gene id: 1134435:AC731_RS17605
uniprot id: A0A127K9N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1134435:AC731 RS18390
gene id: 1134435:AC731_RS18390
uniprot id: A0A127K9U4
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

1134435:AC731 RS00325
gene id: 1134435:AC731_RS00325
uniprot id: A0A140ICR1
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

1134435:AC731 RS02115
gene id: 1134435:AC731_RS02115
uniprot id: A0A140IDM1
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

1134435:AC731 RS07225
gene id: 1134435:AC731_RS07225
uniprot id: A0A127K535
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

1134435:AC731 RS13430
gene id: 1134435:AC731_RS13430
uniprot id: A0A127K7B3
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

1134435:AC731 RS12565
gene id: 1134435:AC731_RS12565
uniprot id: A0A127KB02
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1134435:AC731 RS07650
gene id: 1134435:AC731_RS07650
uniprot id: A0A127K4E1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

1134435:AC731 RS15315
gene id: 1134435:AC731_RS15315
uniprot id: A0A127K8A5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1134435:AC731 RS19095
gene id: 1134435:AC731_RS19095
uniprot id: A0A127KA62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

1134435:AC731 RS01205
gene id: 1134435:AC731_RS01205
uniprot id: A0A140ID60
names: Function
names: Similarity
messages: Belongs to the FliK family.
messages: Controls the length of the flagellar hook.

1134435:AC731 RS02195
gene id: 1134435:AC731_RS02195
uniprot id: A0A140IDN7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

1134435:AC731 RS14445
gene id: 1134435:AC731_RS14445
uniprot id: A0A127K809
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

1134435:AC731 RS10860
gene id: 1134435:AC731_RS10860
uniprot id: A0A127K647
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

1134435:AC731 RS04035
gene id: 1134435:AC731_RS04035
uniprot id: A0A127KAI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

1134435:AC731 RS09835
gene id: 1134435:AC731_RS09835
uniprot id: A0A127K5J6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

1134435:AC731 RS12535
gene id: 1134435:AC731_RS12535
uniprot id: A0A127K6W0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

1134435:AC731 RS17655
gene id: 1134435:AC731_RS17655
uniprot id: A0A127KBB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1134435:AC731 RS08740
gene id: 1134435:AC731_RS08740
uniprot id: A0A127K518
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1134435:AC731 RS07570
gene id: 1134435:AC731_RS07570
uniprot id: A0A127K4D0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

1134435:AC731 RS18555
gene id: 1134435:AC731_RS18555
uniprot id: A0A127KA55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

1134435:AC731 RS14670
gene id: 1134435:AC731_RS14670
uniprot id: A0A127K7Z4
names: Similarity
messages: Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.

1134435:AC731 RS12720
gene id: 1134435:AC731_RS12720
uniprot id: A0A127K6Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

1134435:AC731 RS00875
gene id: 1134435:AC731_RS00875
uniprot id: A0A140ID04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

1134435:AC731 RS10220
gene id: 1134435:AC731_RS10220
uniprot id: A0A127K5R0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

1134435:AC731 RS12515
gene id: 1134435:AC731_RS12515
uniprot id: A0A127K6V6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1134435:AC731 RS14565
gene id: 1134435:AC731_RS14565
uniprot id: A0A127K7Z8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

1134435:AC731 RS04175
gene id: 1134435:AC731_RS04175
uniprot id: A0A140IEM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

1134435:AC731 RS14725
gene id: 1134435:AC731_RS14725
uniprot id: A0A127KB07
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1134435:AC731 RS13965
gene id: 1134435:AC731_RS13965
uniprot id: A0A127K7K9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

1134435:AC731 RS18430
gene id: 1134435:AC731_RS18430
uniprot id: A0A127K9V0
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1134435:AC731 RS18640
gene id: 1134435:AC731_RS18640
uniprot id: A0A127K9Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1134435:AC731 RS10060
gene id: 1134435:AC731_RS10060
uniprot id: A0A127K5N8
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

1134435:AC731 RS10880
gene id: 1134435:AC731_RS10880
uniprot id: A0A127K618
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS01230
gene id: 1134435:AC731_RS01230
uniprot id: A0A140ID65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

1134435:AC731 RS18980
gene id: 1134435:AC731_RS18980
uniprot id: A0A127KA41
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

1134435:AC731 RS16935
gene id: 1134435:AC731_RS16935
uniprot id: A0A127K956
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1134435:AC731 RS16395
gene id: 1134435:AC731_RS16395
uniprot id: A0A127K9M4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

1134435:AC731 RS09380
gene id: 1134435:AC731_RS09380
uniprot id: A0A127K5B8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

1134435:AC731 RS02320
gene id: 1134435:AC731_RS02320
uniprot id: A0A140IDQ8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1134435:AC731 RS08210
gene id: 1134435:AC731_RS08210
uniprot id: A0A127K4P9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1134435:AC731 RS06695
gene id: 1134435:AC731_RS06695
uniprot id: A0A127K3X3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

1134435:AC731 RS11305
gene id: 1134435:AC731_RS11305
uniprot id: A0A127K689
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

1134435:AC731 RS07410
gene id: 1134435:AC731_RS07410
uniprot id: A0A127K4A1
names: Subcellular Location Annotation
messages: Cytoplasm

1134435:AC731 RS01830
gene id: 1134435:AC731_RS01830
uniprot id: A0A140IDH0
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

1134435:AC731 RS03100
gene id: 1134435:AC731_RS03100
uniprot id: A0A140IE40
names: Subcellular Location Annotation
messages: Cytoplasm

1134435:AC731 RS09790
gene id: 1134435:AC731_RS09790
uniprot id: A0A127KAR6
names: Similarity
messages: Belongs to the peptidase U62 family.

1134435:AC731 RS05175
gene id: 1134435:AC731_RS05175
uniprot id: A0A127K343
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.

1134435:AC731 RS10360
gene id: 1134435:AC731_RS10360
uniprot id: A0A127K5W2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1134435:AC731 RS10390
gene id: 1134435:AC731_RS10390
uniprot id: A0A127K5U9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

1134435:AC731 RS11050
gene id: 1134435:AC731_RS11050
uniprot id: A0A127K656
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1134435:AC731 RS02755
gene id: 1134435:AC731_RS02755
uniprot id: A0A140IDY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

1134435:AC731 RS13610
gene id: 1134435:AC731_RS13610
uniprot id: A0A127K7D7
names: Similarity
messages: Belongs to the HypD family.

1134435:AC731 RS03185
gene id: 1134435:AC731_RS03185
uniprot id: A0A140IE53
names: Function
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

1134435:AC731 RS11485
gene id: 1134435:AC731_RS11485
uniprot id: A0A127K6B1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

1134435:AC731 RS16275
gene id: 1134435:AC731_RS16275
uniprot id: A0A127K8V5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

1134435:AC731 RS12670
gene id: 1134435:AC731_RS12670
uniprot id: A0A127K6X3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS13095
gene id: 1134435:AC731_RS13095
uniprot id: A0A127K770
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1134435:AC731 RS13870
gene id: 1134435:AC731_RS13870
uniprot id: A0A127K7Q1
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

1134435:AC731 RS05940
gene id: 1134435:AC731_RS05940
uniprot id: A0A127K3I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

1134435:AC731 RS05020
gene id: 1134435:AC731_RS05020
uniprot id: A0A127K311
names: Similarity
messages: Belongs to the UPF0246 family.

1134435:AC731 RS17510
gene id: 1134435:AC731_RS17510
uniprot id: A0A127K9E3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

1134435:AC731 RS18450
gene id: 1134435:AC731_RS18450
uniprot id: A0A127K9Z6
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

1134435:AC731 RS00820
gene id: 1134435:AC731_RS00820
uniprot id: A0A140ICZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

1134435:AC731 RS03530
gene id: 1134435:AC731_RS03530
uniprot id: A0A140IEB6
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

1134435:AC731 RS16490
gene id: 1134435:AC731_RS16490
uniprot id: A0A127K8Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1134435:AC731 RS12075
gene id: 1134435:AC731_RS12075
uniprot id: A0A127K6N3
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

1134435:AC731 RS01070
gene id: 1134435:AC731_RS01070
uniprot id: A0A140ID34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

1134435:AC731 RS10050
gene id: 1134435:AC731_RS10050
uniprot id: A0A127K5P2
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO large chain family. Type I subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterohexadecamer of 8 large chains and 8 small chains.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.

1134435:AC731 RS00415
gene id: 1134435:AC731_RS00415
uniprot id: A0A140ICS6
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS02625
gene id: 1134435:AC731_RS02625
uniprot id: A0A140IDV7
names: Similarity
messages: Belongs to the SsuE family.

1134435:AC731 RS03045
gene id: 1134435:AC731_RS03045
uniprot id: A0A140IE31
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1134435:AC731 RS11610
gene id: 1134435:AC731_RS11610
uniprot id: A0A127K6E4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

1134435:AC731 RS18660
gene id: 1134435:AC731_RS18660
uniprot id: A0A127KA37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

1134435:AC731 RS18515
gene id: 1134435:AC731_RS18515
uniprot id: A0A127K9X2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

1134435:AC731 RS15000
gene id: 1134435:AC731_RS15000
uniprot id: A0A127K877
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapB family.
messages: Binds 2 heme C groups per subunit.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Electron transfer subunit of the periplasmic nitrate reductase complex NapAB.
messages: Periplasm

1134435:AC731 RS10885
gene id: 1134435:AC731_RS10885
uniprot id: A0A127K629
names: Similarity
messages: Belongs to the ribonuclease N1/T1 family.

1134435:AC731 RS10125
gene id: 1134435:AC731_RS10125
uniprot id: A0A127K5P3
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

1134435:AC731 RS09290
gene id: 1134435:AC731_RS09290
uniprot id: A0A127K588
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1134435:AC731 RS07320
gene id: 1134435:AC731_RS07320
uniprot id: A0A127K483
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

1134435:AC731 RS13605
gene id: 1134435:AC731_RS13605
uniprot id: A0A127K7G7
names: Similarity
messages: Belongs to the HupF/HypC family.

1134435:AC731 RS02970
gene id: 1134435:AC731_RS02970
uniprot id: A0A140IE19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane

1134435:AC731 RS18105
gene id: 1134435:AC731_RS18105
uniprot id: A0A127K9P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

1134435:AC731 RS15025
gene id: 1134435:AC731_RS15025
uniprot id: A0A127K869
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1134435:AC731 RS02225
gene id: 1134435:AC731_RS02225
uniprot id: A0A140IDP2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS18320
gene id: 1134435:AC731_RS18320
uniprot id: A0A127K9T0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

1134435:AC731 RS02135
gene id: 1134435:AC731_RS02135
uniprot id: A0A140IDM5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1134435:AC731 RS14265
gene id: 1134435:AC731_RS14265
uniprot id: A0A127K7Q7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

1134435:AC731 RS18910
gene id: 1134435:AC731_RS18910
uniprot id: A0A127KAB2
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS00450
gene id: 1134435:AC731_RS00450
uniprot id: A0A127KAD4
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

1134435:AC731 RS07945
gene id: 1134435:AC731_RS07945
uniprot id: A0A127K4K0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1134435:AC731 RS08250
gene id: 1134435:AC731_RS08250
uniprot id: A0A127K4R4
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

1134435:AC731 RS08360
gene id: 1134435:AC731_RS08360
uniprot id: A0A127K4S4
names: Similarity
messages: Belongs to the allantoicase family.

1134435:AC731 RS17210
gene id: 1134435:AC731_RS17210
uniprot id: A0A127K987
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

1134435:AC731 RS16365
gene id: 1134435:AC731_RS16365
uniprot id: A0A127K8U0
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS15820
gene id: 1134435:AC731_RS15820
uniprot id: A0A127K8J8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1134435:AC731 RS15710
gene id: 1134435:AC731_RS15710
uniprot id: A0A127K8K0
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

1134435:AC731 RS07655
gene id: 1134435:AC731_RS07655
uniprot id: A0A127K4D9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1134435:AC731 RS08005
gene id: 1134435:AC731_RS08005
uniprot id: A0A127K4K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1134435:AC731 RS03835
gene id: 1134435:AC731_RS03835
uniprot id: A0A140IEG8
names: Similarity
messages: Belongs to the DEAD box helicase family.

1134435:AC731 RS08615
gene id: 1134435:AC731_RS08615
uniprot id: A0A127K4Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

1134435:AC731 RS18960
gene id: 1134435:AC731_RS18960
uniprot id: A0A127KA52
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

1134435:AC731 RS08900
gene id: 1134435:AC731_RS08900
uniprot id: A0A127K545
names: Caution
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS08130
gene id: 1134435:AC731_RS08130
uniprot id: A0A127K4M8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1134435:AC731 RS03825
gene id: 1134435:AC731_RS03825
uniprot id: A0A140IEG6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

1134435:AC731 RS10760
gene id: 1134435:AC731_RS10760
uniprot id: A0A127K5Z9
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS03700
gene id: 1134435:AC731_RS03700
uniprot id: A0A140IEE5
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

1134435:AC731 RS17270
gene id: 1134435:AC731_RS17270
uniprot id: A0A127K9B6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1134435:AC731 RS05070
gene id: 1134435:AC731_RS05070
uniprot id: A0A127K322
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

1134435:AC731 RS17445
gene id: 1134435:AC731_RS17445
uniprot id: A0A127K9K3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1134435:AC731 RS11500
gene id: 1134435:AC731_RS11500
uniprot id: A0A127K6F9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

1134435:AC731 RS13300
gene id: 1134435:AC731_RS13300
uniprot id: A0A127K7B4
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS12320
gene id: 1134435:AC731_RS12320
uniprot id: A0A127K6U7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1134435:AC731 RS05820
gene id: 1134435:AC731_RS05820
uniprot id: A0A127K3G9
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

1134435:AC731 RS15445
gene id: 1134435:AC731_RS15445
uniprot id: A0A127K8B9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1134435:AC731 RS11400
gene id: 1134435:AC731_RS11400
uniprot id: A0A127K6B3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1134435:AC731 RS18435
gene id: 1134435:AC731_RS18435
uniprot id: A0A127K9W4
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

1134435:AC731 RS03915
gene id: 1134435:AC731_RS03915
uniprot id: A0A140IEI4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1134435:AC731 RS02900
gene id: 1134435:AC731_RS02900
uniprot id: A0A140IE06
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1134435:AC731 RS07470
gene id: 1134435:AC731_RS07470
uniprot id: A0A127K4A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

1134435:AC731 RS11810
gene id: 1134435:AC731_RS11810
uniprot id: A0A127K6I1
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS15695
gene id: 1134435:AC731_RS15695
uniprot id: A0A127K8G8
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS13285
gene id: 1134435:AC731_RS13285
uniprot id: A0A127K782
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

1134435:AC731 RS18730
gene id: 1134435:AC731_RS18730
uniprot id: A0A127KA84
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS05095
gene id: 1134435:AC731_RS05095
uniprot id: A0A127K330
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS10890
gene id: 1134435:AC731_RS10890
uniprot id: A0A127K6X1
names: Similarity
messages: Belongs to the barstar family.

1134435:AC731 RS12020
gene id: 1134435:AC731_RS12020
uniprot id: A0A127K6M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

1134435:AC731 RS16335
gene id: 1134435:AC731_RS16335
uniprot id: A0A127K8S8
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS13315
gene id: 1134435:AC731_RS13315
uniprot id: A0A127K7B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

1134435:AC731 RS06215
gene id: 1134435:AC731_RS06215
uniprot id: A0A127K3P0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

1134435:AC731 RS12655
gene id: 1134435:AC731_RS12655
uniprot id: A0A127K6Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

1134435:AC731 RS02520
gene id: 1134435:AC731_RS02520
uniprot id: A0A140IDU0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1134435:AC731 RS15430
gene id: 1134435:AC731_RS15430
uniprot id: A0A127K8B8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1134435:AC731 RS15205
gene id: 1134435:AC731_RS15205
uniprot id: A0A127K873
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

1134435:AC731 RS17480
gene id: 1134435:AC731_RS17480
uniprot id: A0A127K9C1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

1134435:AC731 RS13960
gene id: 1134435:AC731_RS13960
uniprot id: A0A127K7J6
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

1134435:AC731 RS13200
gene id: 1134435:AC731_RS13200
uniprot id: A0A127K795
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1134435:AC731 RS01180
gene id: 1134435:AC731_RS01180
uniprot id: A0A140ID56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

1134435:AC731 RS01050
gene id: 1134435:AC731_RS01050
uniprot id: A0A127KAH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1134435:AC731 RS03870
gene id: 1134435:AC731_RS03870
uniprot id: A0A140IEH5
names: Caution
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

1134435:AC731 RS10275
gene id: 1134435:AC731_RS10275
uniprot id: A0A127K5T0
names: Similarity
messages: Belongs to the fructosamine kinase family.

1134435:AC731 RS12070
gene id: 1134435:AC731_RS12070
uniprot id: A0A127K6M5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

1134435:AC731 RS04520
gene id: 1134435:AC731_RS04520
uniprot id: A0A127K3T2
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

1134435:AC731 RS02125
gene id: 1134435:AC731_RS02125
uniprot id: A0A140IDM3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1134435:AC731 RS05165
gene id: 1134435:AC731_RS05165
uniprot id: A0A127K346
names: Similarity
messages: Belongs to the GSP E family.

1134435:AC731 RS00700
gene id: 1134435:AC731_RS00700
uniprot id: A0A140ICX2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1134435:AC731 RS18755
gene id: 1134435:AC731_RS18755
uniprot id: A0A127KA03
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1134435:AC731 RS05195
gene id: 1134435:AC731_RS05195
uniprot id: A0A127K340
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

1134435:AC731 RS10110
gene id: 1134435:AC731_RS10110
uniprot id: A0A127K5P7
names: Similarity
messages: Belongs to the SAICAR synthetase family.

1134435:AC731 RS14045
gene id: 1134435:AC731_RS14045
uniprot id: A0A127K7L5
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

1134435:AC731 RS12840
gene id: 1134435:AC731_RS12840
uniprot id: A0A127K7U8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

1134435:AC731 RS00090
gene id: 1134435:AC731_RS00090
uniprot id: A0A140ICL7
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

1134435:AC731 RS15560
gene id: 1134435:AC731_RS15560
uniprot id: A0A127K8D7
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

1134435:AC731 RS10385
gene id: 1134435:AC731_RS10385
uniprot id: A0A127K6Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

1134435:AC731 RS07295
gene id: 1134435:AC731_RS07295
uniprot id: A0A127K484
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1134435:AC731 RS01820
gene id: 1134435:AC731_RS01820
uniprot id: A0A127KB93
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

1134435:AC731 RS01040
gene id: 1134435:AC731_RS01040
uniprot id: A0A140ID30
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1134435:AC731 RS02855
gene id: 1134435:AC731_RS02855
uniprot id: A0A140IDZ7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

1134435:AC731 RS13460
gene id: 1134435:AC731_RS13460
uniprot id: A0A127K7B6
names: Similarity
messages: Belongs to the UPF0145 family.

1134435:AC731 RS14225
gene id: 1134435:AC731_RS14225
uniprot id: A0A127K7P2
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS01535
gene id: 1134435:AC731_RS01535
uniprot id: A0A140IDB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diaminopimelate dehydrogenase family.
messages: Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.
messages: Homodimer.

1134435:AC731 RS04775
gene id: 1134435:AC731_RS04775
uniprot id: A0A127K2W9
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS17845
gene id: 1134435:AC731_RS17845
uniprot id: A0A127K9K0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1134435:AC731 RS02345
gene id: 1134435:AC731_RS02345
uniprot id: A0A127KAN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

1134435:AC731 RS10155
gene id: 1134435:AC731_RS10155
uniprot id: A0A127K5Q1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

1134435:AC731 RS03220
gene id: 1134435:AC731_RS03220
uniprot id: A0A140IE59
names: Similarity
messages: Belongs to the UPF0225 family.

1134435:AC731 RS15970
gene id: 1134435:AC731_RS15970
uniprot id: A0A127K8L5
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS02595
gene id: 1134435:AC731_RS02595
uniprot id: A0A140IDV1
names: Similarity
messages: Belongs to the CmpA/NrtA family.

1134435:AC731 RS10020
gene id: 1134435:AC731_RS10020
uniprot id: A0A127K5Q7
names: Similarity
messages: Belongs to the pyruvate kinase family.

1134435:AC731 RS11590
gene id: 1134435:AC731_RS11590
uniprot id: A0A127K6D2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

1134435:AC731 RS14095
gene id: 1134435:AC731_RS14095
uniprot id: A0A127K7M4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

1134435:AC731 RS17455
gene id: 1134435:AC731_RS17455
uniprot id: A0A127K9D4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

1134435:AC731 RS15885
gene id: 1134435:AC731_RS15885
uniprot id: A0A127K8K7
names: Similarity
messages: Belongs to the P(II) protein family.

1134435:AC731 RS13935
gene id: 1134435:AC731_RS13935
uniprot id: A0A127KB54
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

1134435:AC731 RS15055
gene id: 1134435:AC731_RS15055
uniprot id: A0A127K886
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

1134435:AC731 RS13690
gene id: 1134435:AC731_RS13690
uniprot id: A0A127KAZ7
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS13180
gene id: 1134435:AC731_RS13180
uniprot id: A0A127K765
names: Similarity
messages: Belongs to the polysaccharide synthase family.

1134435:AC731 RS03240
gene id: 1134435:AC731_RS03240
uniprot id: A0A140IE63
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

1134435:AC731 RS16425
gene id: 1134435:AC731_RS16425
uniprot id: A0A127K8T2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

1134435:AC731 RS14695
gene id: 1134435:AC731_RS14695
uniprot id: A0A127K7Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1134435:AC731 RS07245
gene id: 1134435:AC731_RS07245
uniprot id: A0A127K479
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS15020
gene id: 1134435:AC731_RS15020
uniprot id: A0A127K845
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1134435:AC731 RS05635
gene id: 1134435:AC731_RS05635
uniprot id: A0A127K3C1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

1134435:AC731 RS11980
gene id: 1134435:AC731_RS11980
uniprot id: A0A127K6K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

1134435:AC731 RS17645
gene id: 1134435:AC731_RS17645
uniprot id: A0A127K9H9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

1134435:AC731 RS13230
gene id: 1134435:AC731_RS13230
uniprot id: A0A127K775
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

1134435:AC731 RS00460
gene id: 1134435:AC731_RS00460
uniprot id: A0A140ICT4
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS04700
gene id: 1134435:AC731_RS04700
uniprot id: A0A127K3W3
names: Function
names: Similarity
messages: Belongs to the PqqB family.
messages: May be involved in the transport of PQQ or its precursor to the periplasm.

1134435:AC731 RS06725
gene id: 1134435:AC731_RS06725
uniprot id: A0A127K3W9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

1134435:AC731 RS10470
gene id: 1134435:AC731_RS10470
uniprot id: A0A127K5U7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

1134435:AC731 RS04765
gene id: 1134435:AC731_RS04765
uniprot id: A0A127K3X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1134435:AC731 RS07380
gene id: 1134435:AC731_RS07380
uniprot id: A0A127K570
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

1134435:AC731 RS10565
gene id: 1134435:AC731_RS10565
uniprot id: A0A127K5Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1134435:AC731 RS17310
gene id: 1134435:AC731_RS17310
uniprot id: A0A127K9A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1134435:AC731 RS09930
gene id: 1134435:AC731_RS09930
uniprot id: A0A127K5L4
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

1134435:AC731 RS09355
gene id: 1134435:AC731_RS09355
uniprot id: A0A127K5A7
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS16070
gene id: 1134435:AC731_RS16070
uniprot id: A0A127K8P9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1134435:AC731 RS06140
gene id: 1134435:AC731_RS06140
uniprot id: A0A127K4L5
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

1134435:AC731 RS09650
gene id: 1134435:AC731_RS09650
uniprot id: A0A127K5G9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS14125
gene id: 1134435:AC731_RS14125
uniprot id: A0A127K7V0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

1134435:AC731 RS10305
gene id: 1134435:AC731_RS10305
uniprot id: A0A127KAS1
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

1134435:AC731 RS19090
gene id: 1134435:AC731_RS19090
uniprot id: A0A127KAA5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS12290
gene id: 1134435:AC731_RS12290
uniprot id: A0A127KAY2
names: Similarity
messages: Belongs to the peptidase M16 family.

1134435:AC731 RS06210
gene id: 1134435:AC731_RS06210
uniprot id: A0A127K3N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

1134435:AC731 RS04975
gene id: 1134435:AC731_RS04975
uniprot id: A0A127K309
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

1134435:AC731 RS18330
gene id: 1134435:AC731_RS18330
uniprot id: A0A127K9T3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

1134435:AC731 RS00785
gene id: 1134435:AC731_RS00785
uniprot id: A0A140ICY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

1134435:AC731 RS04095
gene id: 1134435:AC731_RS04095
uniprot id: A0A140IEL5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

1134435:AC731 RS19145
gene id: 1134435:AC731_RS19145
uniprot id: A0A127KAB5
names: Similarity
messages: Belongs to the DEAD box helicase family.

1134435:AC731 RS14815
gene id: 1134435:AC731_RS14815
uniprot id: A0A127K828
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS18085
gene id: 1134435:AC731_RS18085
uniprot id: A0A127K9Q3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

1134435:AC731 RS01200
gene id: 1134435:AC731_RS01200
uniprot id: A0A140ID59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

1134435:AC731 RS12350
gene id: 1134435:AC731_RS12350
uniprot id: A0A127K7M5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

1134435:AC731 RS05110
gene id: 1134435:AC731_RS05110
uniprot id: A0A127K334
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

1134435:AC731 RS02275
gene id: 1134435:AC731_RS02275
uniprot id: A0A140IDP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

1134435:AC731 RS01155
gene id: 1134435:AC731_RS01155
uniprot id: A0A140ID51
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

1134435:AC731 RS14540
gene id: 1134435:AC731_RS14540
uniprot id: A0A127K7W9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1134435:AC731 RS15765
gene id: 1134435:AC731_RS15765
uniprot id: A0A127K8I4
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1134435:AC731 RS09960
gene id: 1134435:AC731_RS09960
uniprot id: A0A127K5M0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

1134435:AC731 RS00780
gene id: 1134435:AC731_RS00780
uniprot id: A0A140ICY7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS03985
gene id: 1134435:AC731_RS03985
uniprot id: A0A140IEJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

1134435:AC731 RS13715
gene id: 1134435:AC731_RS13715
uniprot id: A0A127K7F0
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

1134435:AC731 RS13905
gene id: 1134435:AC731_RS13905
uniprot id: A0A127K7I4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

1134435:AC731 RS04600
gene id: 1134435:AC731_RS04600
uniprot id: A0A127K2V1
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

1134435:AC731 RS12965
gene id: 1134435:AC731_RS12965
uniprot id: A0A127K720
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

1134435:AC731 RS12510
gene id: 1134435:AC731_RS12510
uniprot id: A0A127K6W8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS08115
gene id: 1134435:AC731_RS08115
uniprot id: A0A127K4M2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1134435:AC731 RS17415
gene id: 1134435:AC731_RS17415
uniprot id: A0A127K9B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

1134435:AC731 RS08150
gene id: 1134435:AC731_RS08150
uniprot id: A0A127K4P1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS15770
gene id: 1134435:AC731_RS15770
uniprot id: A0A127K9B8
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1134435:AC731 RS07335
gene id: 1134435:AC731_RS07335
uniprot id: A0A127K497
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

1134435:AC731 RS16740
gene id: 1134435:AC731_RS16740
uniprot id: A0A127K910
names: Subcellular Location Annotation
messages: Cytoplasm

1134435:AC731 RS08880
gene id: 1134435:AC731_RS08880
uniprot id: A0A127K524
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1134435:AC731 RS02915
gene id: 1134435:AC731_RS02915
uniprot id: A0A140IE08
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1134435:AC731 RS15095
gene id: 1134435:AC731_RS15095
uniprot id: A0A127K866
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS16360
gene id: 1134435:AC731_RS16360
uniprot id: A0A127K8R8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

1134435:AC731 RS01120
gene id: 1134435:AC731_RS01120
uniprot id: A0A140ID44
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

1134435:AC731 RS06705
gene id: 1134435:AC731_RS06705
uniprot id: A0A127K3Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

1134435:AC731 RS14550
gene id: 1134435:AC731_RS14550
uniprot id: A0A127K7W8
names: Similarity
messages: Belongs to the Smg family.

1134435:AC731 RS08930
gene id: 1134435:AC731_RS08930
uniprot id: A0A127K538
names: Similarity
messages: Belongs to the CcdB toxin family.

1134435:AC731 RS08010
gene id: 1134435:AC731_RS08010
uniprot id: A0A127KA69
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1134435:AC731 RS14185
gene id: 1134435:AC731_RS14185
uniprot id: A0A127K7S1
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS18970
gene id: 1134435:AC731_RS18970
uniprot id: A0A127KAC3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

1134435:AC731 RS01085
gene id: 1134435:AC731_RS01085
uniprot id: A0A140ID37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1134435:AC731 RS09935
gene id: 1134435:AC731_RS09935
uniprot id: A0A127KAV3
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS01195
gene id: 1134435:AC731_RS01195
uniprot id: A0A140ID58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

1134435:AC731 RS15380
gene id: 1134435:AC731_RS15380
uniprot id: A0A127K8A4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

1134435:AC731 RS17725
gene id: 1134435:AC731_RS17725
uniprot id: A0A127KAC6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1134435:AC731 RS14260
gene id: 1134435:AC731_RS14260
uniprot id: A0A127K7R9
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS14575
gene id: 1134435:AC731_RS14575
uniprot id: A0A127K8P5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

1134435:AC731 RS07340
gene id: 1134435:AC731_RS07340
uniprot id: A0A127K4A2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

1134435:AC731 RS03745
gene id: 1134435:AC731_RS03745
uniprot id: A0A140IEF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

1134435:AC731 RS08420
gene id: 1134435:AC731_RS08420
uniprot id: A0A127K4T1
names: Similarity
messages: Belongs to the hyi family.

1134435:AC731 RS12975
gene id: 1134435:AC731_RS12975
uniprot id: A0A127K726
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1134435:AC731 RS00750
gene id: 1134435:AC731_RS00750
uniprot id: A0A140ICY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

1134435:AC731 RS13390
gene id: 1134435:AC731_RS13390
uniprot id: A0A127K7A3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

1134435:AC731 RS09165
gene id: 1134435:AC731_RS09165
uniprot id: A0A127K573
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1134435:AC731 RS17850
gene id: 1134435:AC731_RS17850
uniprot id: A0A127K9L2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1134435:AC731 RS17280
gene id: 1134435:AC731_RS17280
uniprot id: A0A127K9H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1134435:AC731 RS12420
gene id: 1134435:AC731_RS12420
uniprot id: A0A127K6U2
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS02300
gene id: 1134435:AC731_RS02300
uniprot id: A0A140IDQ4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

1134435:AC731 RS14105
gene id: 1134435:AC731_RS14105
uniprot id: A0A127K7N9
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS02825
gene id: 1134435:AC731_RS02825
uniprot id: A0A140IDZ1
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

1134435:AC731 RS20180
gene id: 1134435:AC731_RS20180
uniprot id: A0A127KA69
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

1134435:AC731 RS17265
gene id: 1134435:AC731_RS17265
uniprot id: A0A127K983
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

1134435:AC731 RS17400
gene id: 1134435:AC731_RS17400
uniprot id: A0A127K9G4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1134435:AC731 RS14555
gene id: 1134435:AC731_RS14555
uniprot id: A0A127K7V4
names: Similarity
messages: Belongs to the DprA/Smf family.

1134435:AC731 RS14545
gene id: 1134435:AC731_RS14545
uniprot id: A0A127K7V1
names: Similarity
messages: Belongs to the type IA topoisomerase family.

1134435:AC731 RS10850
gene id: 1134435:AC731_RS10850
uniprot id: A0A127K605
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

1134435:AC731 RS10145
gene id: 1134435:AC731_RS10145
uniprot id: A0A127K6L9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

1134435:AC731 RS18990
gene id: 1134435:AC731_RS18990
uniprot id: A0A127KA47
names: Similarity
messages: Belongs to the hemerythrin family.

1134435:AC731 RS03040
gene id: 1134435:AC731_RS03040
uniprot id: A0A127KAJ5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

1134435:AC731 RS05045
gene id: 1134435:AC731_RS05045
uniprot id: A0A127K317
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

1134435:AC731 RS00295
gene id: 1134435:AC731_RS00295
uniprot id: A0A140ICQ6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

1134435:AC731 RS14035
gene id: 1134435:AC731_RS14035
uniprot id: A0A127K7K6
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

1134435:AC731 RS14100
gene id: 1134435:AC731_RS14100
uniprot id: A0A127K7M6
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS04070
gene id: 1134435:AC731_RS04070
uniprot id: A0A127KAK0
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

1134435:AC731 RS08235
gene id: 1134435:AC731_RS08235
uniprot id: A0A127K4N8
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

1134435:AC731 RS02215
gene id: 1134435:AC731_RS02215
uniprot id: A0A140IDP0
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

1134435:AC731 RS00800
gene id: 1134435:AC731_RS00800
uniprot id: A0A140ICZ1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1134435:AC731 RS03855
gene id: 1134435:AC731_RS03855
uniprot id: A0A140IEH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

1134435:AC731 RS07520
gene id: 1134435:AC731_RS07520
uniprot id: A0A127K4B5
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS11445
gene id: 1134435:AC731_RS11445
uniprot id: A0A127K6E5
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

1134435:AC731 RS11475
gene id: 1134435:AC731_RS11475
uniprot id: A0A127K6B0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

1134435:AC731 RS16695
gene id: 1134435:AC731_RS16695
uniprot id: A0A127K8Y3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

1134435:AC731 RS03770
gene id: 1134435:AC731_RS03770
uniprot id: A0A127KBC3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

1134435:AC731 RS06715
gene id: 1134435:AC731_RS06715
uniprot id: A0A127K3X9
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

1134435:AC731 RS04155
gene id: 1134435:AC731_RS04155
uniprot id: A0A140IEM5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

1134435:AC731 RS01300
gene id: 1134435:AC731_RS01300
uniprot id: A0A140ID77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

1134435:AC731 RS15925
gene id: 1134435:AC731_RS15925
uniprot id: A0A127K8S6
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS03955
gene id: 1134435:AC731_RS03955
uniprot id: A0A140IEJ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1134435:AC731 RS08670
gene id: 1134435:AC731_RS08670
uniprot id: A0A127K4Z2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1134435:AC731 RS01075
gene id: 1134435:AC731_RS01075
uniprot id: A0A140ID35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

1134435:AC731 RS18045
gene id: 1134435:AC731_RS18045
uniprot id: A0A127KB52
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1134435:AC731 RS19365
gene id: 1134435:AC731_RS19365
uniprot id: A0A127KAB7
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

1134435:AC731 RS16190
gene id: 1134435:AC731_RS16190
uniprot id: A0A127K8P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

1134435:AC731 RS01815
gene id: 1134435:AC731_RS01815
uniprot id: A0A140IDG8
names: Caution
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS10410
gene id: 1134435:AC731_RS10410
uniprot id: A0A127K5U0
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS09270
gene id: 1134435:AC731_RS09270
uniprot id: A0A127K644
names: Similarity
messages: Belongs to the universal stress protein A family.

1134435:AC731 RS02205
gene id: 1134435:AC731_RS02205
uniprot id: A0A140IDN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Membrane

1134435:AC731 RS08955
gene id: 1134435:AC731_RS08955
uniprot id: A0A127K531
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1134435:AC731 RS11025
gene id: 1134435:AC731_RS11025
uniprot id: A0A127K674
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

1134435:AC731 RS06235
gene id: 1134435:AC731_RS06235
uniprot id: A0A127K3N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

1134435:AC731 RS01675
gene id: 1134435:AC731_RS01675
uniprot id: A0A140IDE1
names: Similarity
messages: Belongs to the asparaginase 1 family.

1134435:AC731 RS13005
gene id: 1134435:AC731_RS13005
uniprot id: A0A127K728
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1134435:AC731 RS11075
gene id: 1134435:AC731_RS11075
uniprot id: A0A127K642
names: Similarity
messages: Belongs to the peptidase S11 family.

1134435:AC731 RS04715
gene id: 1134435:AC731_RS04715
uniprot id: A0A127K2V9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. PqqE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
messages: Interacts with PqqD. The interaction is necessary for activity of PqqE.

1134435:AC731 RS18650
gene id: 1134435:AC731_RS18650
uniprot id: A0A127K9Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

1134435:AC731 RS18495
gene id: 1134435:AC731_RS18495
uniprot id: A0A127K9W6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

1134435:AC731 RS18125
gene id: 1134435:AC731_RS18125
uniprot id: A0A127KAJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1134435:AC731 RS18055
gene id: 1134435:AC731_RS18055
uniprot id: A0A127K9W5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS00945
gene id: 1134435:AC731_RS00945
uniprot id: A0A127KAE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

1134435:AC731 RS12605
gene id: 1134435:AC731_RS12605
uniprot id: A0A127K6W4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

1134435:AC731 RS11560
gene id: 1134435:AC731_RS11560
uniprot id: A0A127KAX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

1134435:AC731 RS19270
gene id: 1134435:AC731_RS19270
uniprot id: A0A127KAD5
names: Similarity
messages: Belongs to the peptidase U62 family.

1134435:AC731 RS18580
gene id: 1134435:AC731_RS18580
uniprot id: A0A127KA02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

1134435:AC731 RS18260
gene id: 1134435:AC731_RS18260
uniprot id: A0A127K9T4
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

1134435:AC731 RS05790
gene id: 1134435:AC731_RS05790
uniprot id: A0A127K3F1
names: Similarity
messages: Belongs to the hemerythrin family.

1134435:AC731 RS13030
gene id: 1134435:AC731_RS13030
uniprot id: A0A127K736
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1134435:AC731 RS09385
gene id: 1134435:AC731_RS09385
uniprot id: A0A127K5B6
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

1134435:AC731 RS18655
gene id: 1134435:AC731_RS18655
uniprot id: A0A127KA74
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

1134435:AC731 RS00195
gene id: 1134435:AC731_RS00195
uniprot id: A0A140ICN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1134435:AC731 RS13825
gene id: 1134435:AC731_RS13825
uniprot id: A0A127K7G3
names: Similarity
messages: Belongs to the peptidase C56 family.

1134435:AC731 RS10045
gene id: 1134435:AC731_RS10045
uniprot id: A0A127K6K1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1134435:AC731 RS01605
gene id: 1134435:AC731_RS01605
uniprot id: A0A140IDC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1134435:AC731 RS07365
gene id: 1134435:AC731_RS07365
uniprot id: A0A127K485
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1134435:AC731 RS07940
gene id: 1134435:AC731_RS07940
uniprot id: A0A127K4J4
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS05130
gene id: 1134435:AC731_RS05130
uniprot id: A0A127K336
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

1134435:AC731 RS16920
gene id: 1134435:AC731_RS16920
uniprot id: A0A127K9X7
names: Function
names: Similarity
messages: Belongs to the bacterial two-domain DSD family.
messages: Catalyzes the conversion of 3-dehydroshikimate to protocatechuate (3,4-dihydroxybenzoate), a common intermediate of quinate and shikimate degradation pathways.

1134435:AC731 RS05715
gene id: 1134435:AC731_RS05715
uniprot id: A0A127K3E3
names: Similarity
messages: Belongs to the hemerythrin family.

1134435:AC731 RS03075
gene id: 1134435:AC731_RS03075
uniprot id: A0A140IE35
names: Similarity
messages: Belongs to the RecJ family.

1134435:AC731 RS01080
gene id: 1134435:AC731_RS01080
uniprot id: A0A140ID36
names: Similarity
messages: Belongs to the MotB family.

1134435:AC731 RS00705
gene id: 1134435:AC731_RS00705
uniprot id: A0A140ICX3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1134435:AC731 RS17305
gene id: 1134435:AC731_RS17305
uniprot id: A0A127K999
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

1134435:AC731 RS07325
gene id: 1134435:AC731_RS07325
uniprot id: A0A127K487
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

1134435:AC731 RS00940
gene id: 1134435:AC731_RS00940
uniprot id: A0A140ID14
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1134435:AC731 RS13930
gene id: 1134435:AC731_RS13930
uniprot id: A0A127K7I9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1134435:AC731 RS12470
gene id: 1134435:AC731_RS12470
uniprot id: A0A127K6V1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

1134435:AC731 RS09890
gene id: 1134435:AC731_RS09890
uniprot id: A0A127K5K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

1134435:AC731 RS05620
gene id: 1134435:AC731_RS05620
uniprot id: A0A127K3C7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

1134435:AC731 RS01055
gene id: 1134435:AC731_RS01055
uniprot id: A0A140ID31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

1134435:AC731 RS12775
gene id: 1134435:AC731_RS12775
uniprot id: A0A127K6Z4
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

1134435:AC731 RS08765
gene id: 1134435:AC731_RS08765
uniprot id: A0A127K506
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1134435:AC731 RS04915
gene id: 1134435:AC731_RS04915
uniprot id: A0A127K2Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FTR family.
messages: Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT).
messages: Cytoplasm
messages: Homotetramer.

1134435:AC731 RS05140
gene id: 1134435:AC731_RS05140
uniprot id: A0A127K331
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS13360
gene id: 1134435:AC731_RS13360
uniprot id: A0A127K799
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

1134435:AC731 RS13410
gene id: 1134435:AC731_RS13410
uniprot id: A0A127K7D3
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS07350
gene id: 1134435:AC731_RS07350
uniprot id: A0A127K499
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

1134435:AC731 RS03120
gene id: 1134435:AC731_RS03120
uniprot id: A0A140IE42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

1134435:AC731 RS14750
gene id: 1134435:AC731_RS14750
uniprot id: A0A127K7Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

1134435:AC731 RS04630
gene id: 1134435:AC731_RS04630
uniprot id: A0A127K2U3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

1134435:AC731 RS16760
gene id: 1134435:AC731_RS16760
uniprot id: A0A127K907
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1134435:AC731 RS16210
gene id: 1134435:AC731_RS16210
uniprot id: A0A127K8Q4
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1134435:AC731 RS07345
gene id: 1134435:AC731_RS07345
uniprot id: A0A127K493
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

1134435:AC731 RS02155
gene id: 1134435:AC731_RS02155
uniprot id: A0A140IDM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

1134435:AC731 RS07770
gene id: 1134435:AC731_RS07770
uniprot id: A0A127K4F9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

1134435:AC731 RS06805
gene id: 1134435:AC731_RS06805
uniprot id: A0A127K3Z6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

1134435:AC731 RS14290
gene id: 1134435:AC731_RS14290
uniprot id: A0A127K7U6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the precorrin methyltransferase family.
messages: Homodimer.
messages: Methylates precorrin-2 at the C-20 position to produce precorrin-3A.

1134435:AC731 RS16400
gene id: 1134435:AC731_RS16400
uniprot id: A0A127K8T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1134435:AC731 RS11425
gene id: 1134435:AC731_RS11425
uniprot id: A0A127KAV8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1134435:AC731 RS12295
gene id: 1134435:AC731_RS12295
uniprot id: A0A127K7L2
names: Similarity
messages: Belongs to the peptidase M16 family.

1134435:AC731 RS15845
gene id: 1134435:AC731_RS15845
uniprot id: A0A127K8I6
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

1134435:AC731 RS02105
gene id: 1134435:AC731_RS02105
uniprot id: A0A140IDL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1134435:AC731 RS19215
gene id: 1134435:AC731_RS19215
uniprot id: A0A127KA87
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

1134435:AC731 RS11455
gene id: 1134435:AC731_RS11455
uniprot id: A0A127K6C1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

1134435:AC731 RS00075
gene id: 1134435:AC731_RS00075
uniprot id: A0A140ICL5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS01990
gene id: 1134435:AC731_RS01990
uniprot id: A0A140IDJ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS09295
gene id: 1134435:AC731_RS09295
uniprot id: A0A127K599
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

1134435:AC731 RS04405
gene id: 1134435:AC731_RS04405
uniprot id: A0A127K2Q5
names: Similarity
messages: Belongs to the ArsC family.

1134435:AC731 RS01980
gene id: 1134435:AC731_RS01980
uniprot id: A0A140IDJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

1134435:AC731 RS09700
gene id: 1134435:AC731_RS09700
uniprot id: A0A127K5I3
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

1134435:AC731 RS11990
gene id: 1134435:AC731_RS11990
uniprot id: A0A127K6Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

1134435:AC731 RS03335
gene id: 1134435:AC731_RS03335
uniprot id: A0A140IE79
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

1134435:AC731 RS14280
gene id: 1134435:AC731_RS14280
uniprot id: A0A127K7Q3
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

1134435:AC731 RS18270
gene id: 1134435:AC731_RS18270
uniprot id: A0A127KA07
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1134435:AC731 RS14880
gene id: 1134435:AC731_RS14880
uniprot id: A0A127K826
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1134435:AC731 RS13750
gene id: 1134435:AC731_RS13750
uniprot id: A0A127K7G2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1134435:AC731 RS06625
gene id: 1134435:AC731_RS06625
uniprot id: A0A127K3V7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

1134435:AC731 RS00795
gene id: 1134435:AC731_RS00795
uniprot id: A0A140ICZ0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

1134435:AC731 RS12195
gene id: 1134435:AC731_RS12195
uniprot id: A0A127K6Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

1134435:AC731 RS11010
gene id: 1134435:AC731_RS11010
uniprot id: A0A127K628
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS00140
gene id: 1134435:AC731_RS00140
uniprot id: A0A140ICM7
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

1134435:AC731 RS11535
gene id: 1134435:AC731_RS11535
uniprot id: A0A127K6C2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

1134435:AC731 RS12525
gene id: 1134435:AC731_RS12525
uniprot id: A0A127K6V9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

1134435:AC731 RS09760
gene id: 1134435:AC731_RS09760
uniprot id: A0A127KAS7
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1134435:AC731 RS18350
gene id: 1134435:AC731_RS18350
uniprot id: A0A127KBB7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS11745
gene id: 1134435:AC731_RS11745
uniprot id: A0A127K7C0
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS16660
gene id: 1134435:AC731_RS16660
uniprot id: A0A127K8Y7
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

1134435:AC731 RS17385
gene id: 1134435:AC731_RS17385
uniprot id: A0A127K9D0
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS04100
gene id: 1134435:AC731_RS04100
uniprot id: A0A140IEL6
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

1134435:AC731 RS16385
gene id: 1134435:AC731_RS16385
uniprot id: A0A127K8X9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1134435:AC731 RS16390
gene id: 1134435:AC731_RS16390
uniprot id: A0A127K8T5
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

1134435:AC731 RS11385
gene id: 1134435:AC731_RS11385
uniprot id: A0A127K6B9
names: Function
names: Subunit
messages: Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein.
messages: Monomer in both c-di-GMP-bound and free forms.

1134435:AC731 RS12065
gene id: 1134435:AC731_RS12065
uniprot id: A0A127K6R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1134435:AC731 RS03805
gene id: 1134435:AC731_RS03805
uniprot id: A0A140IEG3
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

1134435:AC731 RS18525
gene id: 1134435:AC731_RS18525
uniprot id: A0A127K9X1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

1134435:AC731 RS10855
gene id: 1134435:AC731_RS10855
uniprot id: A0A127K602
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

1134435:AC731 RS06880
gene id: 1134435:AC731_RS06880
uniprot id: A0A127K404
names: Subcellular Location Annotation
messages: Cell inner membrane

1134435:AC731 RS11670
gene id: 1134435:AC731_RS11670
uniprot id: A0A127K6G2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1134435:AC731 RS01060
gene id: 1134435:AC731_RS01060
uniprot id: A0A140ID32
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

1134435:AC731 RS15870
gene id: 1134435:AC731_RS15870
uniprot id: A0A127K8N7
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

1134435:AC731 RS14060
gene id: 1134435:AC731_RS14060
uniprot id: A0A127K7L7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

1134435:AC731 RS04040
gene id: 1134435:AC731_RS04040
uniprot id: A0A140IEK6
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS11895
gene id: 1134435:AC731_RS11895
uniprot id: A0A127K6J8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

1134435:AC731 RS18120
gene id: 1134435:AC731_RS18120
uniprot id: A0A127K9Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

1134435:AC731 RS03785
gene id: 1134435:AC731_RS03785
uniprot id: A0A140IEF9
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

1134435:AC731 RS14430
gene id: 1134435:AC731_RS14430
uniprot id: A0A127K7T7
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

1134435:AC731 RS16540
gene id: 1134435:AC731_RS16540
uniprot id: A0A127K933
names: Similarity
messages: Belongs to the RutC family.

1134435:AC731 RS14490
gene id: 1134435:AC731_RS14490
uniprot id: A0A127K7V8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aromatic amine dehydrogenase light chain family.
messages: Heterotetramer of two light and two heavy chains.
messages: Methylamine dehydrogenase carries out the oxidation of methylamine. Electrons are passed from methylamine dehydrogenase to amicyanin.
messages: Periplasm

1134435:AC731 RS00375
gene id: 1134435:AC731_RS00375
uniprot id: A0A140ICS0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

1134435:AC731 RS02095
gene id: 1134435:AC731_RS02095
uniprot id: A0A140IDL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1134435:AC731 RS14075
gene id: 1134435:AC731_RS14075
uniprot id: A0A127K7U0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

1134435:AC731 RS18425
gene id: 1134435:AC731_RS18425
uniprot id: A0A127K9W8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

1134435:AC731 RS03390
gene id: 1134435:AC731_RS03390
uniprot id: A0A140IE89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

1134435:AC731 RS04300
gene id: 1134435:AC731_RS04300
uniprot id: A0A140IEP7
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

1134435:AC731 RS10225
gene id: 1134435:AC731_RS10225
uniprot id: A0A127KAY5
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

1134435:AC731 RS03895
gene id: 1134435:AC731_RS03895
uniprot id: A0A140IEI0
names: Similarity
messages: Belongs to the UPF0234 family.

1134435:AC731 RS13555
gene id: 1134435:AC731_RS13555
uniprot id: A0A127K7J4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

1134435:AC731 RS02940
gene id: 1134435:AC731_RS02940
uniprot id: A0A140IE13
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

1134435:AC731 RS16585
gene id: 1134435:AC731_RS16585
uniprot id: A0A127K8Y0
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

1134435:AC731 RS11285
gene id: 1134435:AC731_RS11285
uniprot id: A0A127K6C0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1134435:AC731 RS14535
gene id: 1134435:AC731_RS14535
uniprot id: A0A127K7V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

1134435:AC731 RS10695
gene id: 1134435:AC731_RS10695
uniprot id: A0A127K620
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

1134435:AC731 RS09080
gene id: 1134435:AC731_RS09080
uniprot id: A0A127K559
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

1134435:AC731 RS17100
gene id: 1134435:AC731_RS17100
uniprot id: A0A127K981
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

1134435:AC731 RS10120
gene id: 1134435:AC731_RS10120
uniprot id: A0A127K5S0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

1134435:AC731 RS17255
gene id: 1134435:AC731_RS17255
uniprot id: A0A127K990
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS11460
gene id: 1134435:AC731_RS11460
uniprot id: A0A127K767
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

1134435:AC731 RS08910
gene id: 1134435:AC731_RS08910
uniprot id: A0A127K529
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS16610
gene id: 1134435:AC731_RS16610
uniprot id: A0A127K8X5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

1134435:AC731 RS10310
gene id: 1134435:AC731_RS10310
uniprot id: A0A127K5U4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

1134435:AC731 RS13080
gene id: 1134435:AC731_RS13080
uniprot id: A0A127K743
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1134435:AC731 RS12365
gene id: 1134435:AC731_RS12365
uniprot id: A0A127K6T0
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

1134435:AC731 RS18510
gene id: 1134435:AC731_RS18510
uniprot id: A0A127KA06
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS10175
gene id: 1134435:AC731_RS10175
uniprot id: A0A127K5P9
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

1134435:AC731 RS06750
gene id: 1134435:AC731_RS06750
uniprot id: A0A127K3Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

1134435:AC731 RS14855
gene id: 1134435:AC731_RS14855
uniprot id: A0A127K8U5
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS14910
gene id: 1134435:AC731_RS14910
uniprot id: A0A127K820
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

1134435:AC731 RS00805
gene id: 1134435:AC731_RS00805
uniprot id: A0A140ICZ2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

1134435:AC731 RS19340
gene id: 1134435:AC731_RS19340
uniprot id: A0A127KAA9
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

1134435:AC731 RS01395
gene id: 1134435:AC731_RS01395
uniprot id: A0A140ID95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

1134435:AC731 RS11715
gene id: 1134435:AC731_RS11715
uniprot id: A0A127K6F0
names: Subcellular Location Annotation
messages: Cell inner membrane

1134435:AC731 RS11525
gene id: 1134435:AC731_RS11525
uniprot id: A0A127K6C3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

1134435:AC731 RS02150
gene id: 1134435:AC731_RS02150
uniprot id: A0A140IDM8
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS11605
gene id: 1134435:AC731_RS11605
uniprot id: A0A127K6G2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

1134435:AC731 RS12220
gene id: 1134435:AC731_RS12220
uniprot id: A0A127K6R2
names: Similarity
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.

1134435:AC731 RS15900
gene id: 1134435:AC731_RS15900
uniprot id: A0A127K8J5
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

1134435:AC731 RS10065
gene id: 1134435:AC731_RS10065
uniprot id: A0A127K5N1
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS07505
gene id: 1134435:AC731_RS07505
uniprot id: A0A127K4C9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

1134435:AC731 RS08245
gene id: 1134435:AC731_RS08245
uniprot id: A0A127K4Q6
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

1134435:AC731 RS13550
gene id: 1134435:AC731_RS13550
uniprot id: A0A127K7C7
names: Similarity
messages: Belongs to the CutA family.

1134435:AC731 RS08675
gene id: 1134435:AC731_RS08675
uniprot id: A0A127K500
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Catalyzes the synthesis of activated sulfate.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

1134435:AC731 RS06810
gene id: 1134435:AC731_RS06810
uniprot id: A0A127KAQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

1134435:AC731 RS00760
gene id: 1134435:AC731_RS00760
uniprot id: A0A140ICY3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

1134435:AC731 RS01105
gene id: 1134435:AC731_RS01105
uniprot id: A0A140ID41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

1134435:AC731 RS11465
gene id: 1134435:AC731_RS11465
uniprot id: A0A127K6B5
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

1134435:AC731 RS02260
gene id: 1134435:AC731_RS02260
uniprot id: A0A140IDP6
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

1134435:AC731 RS13980
gene id: 1134435:AC731_RS13980
uniprot id: A0A127K7N1
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

1134435:AC731 RS03295
gene id: 1134435:AC731_RS03295
uniprot id: A0A140IE72
names: Cofactor
names: Subunit
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

1134435:AC731 RS17150
gene id: 1134435:AC731_RS17150
uniprot id: A0A127KB49
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS17995
gene id: 1134435:AC731_RS17995
uniprot id: A0A127K9M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

1134435:AC731 RS10940
gene id: 1134435:AC731_RS10940
uniprot id: A0A127K638
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

1134435:AC731 RS18505
gene id: 1134435:AC731_RS18505
uniprot id: A0A127KA45
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.

1134435:AC731 RS11640
gene id: 1134435:AC731_RS11640
uniprot id: A0A127K6E1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

1134435:AC731 RS09255
gene id: 1134435:AC731_RS09255
uniprot id: A0A127K5A2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

1134435:AC731 RS07515
gene id: 1134435:AC731_RS07515
uniprot id: A0A127K4C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

1134435:AC731 RS06320
gene id: 1134435:AC731_RS06320
uniprot id: A0A127K3Q6
names: Similarity
messages: Belongs to the Ahb/Nir family.

1134435:AC731 RS00880
gene id: 1134435:AC731_RS00880
uniprot id: A0A140ID05
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

1134435:AC731 RS01935
gene id: 1134435:AC731_RS01935
uniprot id: A0A140IDI8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1134435:AC731 RS01250
gene id: 1134435:AC731_RS01250
uniprot id: A0A140ID68
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

1134435:AC731 RS02185
gene id: 1134435:AC731_RS02185
uniprot id: A0A140IDN5
names: Similarity
messages: Belongs to the P(II) protein family.

1134435:AC731 RS12530
gene id: 1134435:AC731_RS12530
uniprot id: A0A127K6V3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.

1134435:AC731 RS10000
gene id: 1134435:AC731_RS10000
uniprot id: A0A127K5N2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

1134435:AC731 RS15935
gene id: 1134435:AC731_RS15935
uniprot id: A0A127K8L7
names: Similarity
messages: Belongs to the leucine-binding protein family.

1134435:AC731 RS12335
gene id: 1134435:AC731_RS12335
uniprot id: A0A127K6T8
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

1134435:AC731 RS00590
gene id: 1134435:AC731_RS00590
uniprot id: A0A140ICV7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1134435:AC731 RS03710
gene id: 1134435:AC731_RS03710
uniprot id: A0A140IEE7
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

1134435:AC731 RS14985
gene id: 1134435:AC731_RS14985
uniprot id: A0A127K846
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

1134435:AC731 RS16065
gene id: 1134435:AC731_RS16065
uniprot id: A0A127K8M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

1134435:AC731 RS16205
gene id: 1134435:AC731_RS16205
uniprot id: A0A127K8N8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

1134435:AC731 RS17615
gene id: 1134435:AC731_RS17615
uniprot id: A0A127K9G3
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

1134435:AC731 RS02950
gene id: 1134435:AC731_RS02950
uniprot id: A0A140IE15
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS05600
gene id: 1134435:AC731_RS05600
uniprot id: A0A127K3C4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

1134435:AC731 RS16240
gene id: 1134435:AC731_RS16240
uniprot id: A0A127K8Q3
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS11965
gene id: 1134435:AC731_RS11965
uniprot id: A0A127KAU6
names: Similarity
messages: Belongs to the Fur family.

1134435:AC731 RS13465
gene id: 1134435:AC731_RS13465
uniprot id: A0A127K7E2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

1134435:AC731 RS10895
gene id: 1134435:AC731_RS10895
uniprot id: A0A127K621
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

1134435:AC731 RS09905
gene id: 1134435:AC731_RS09905
uniprot id: A0A127K5K7
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

1134435:AC731 RS14810
gene id: 1134435:AC731_RS14810
uniprot id: A0A127K804
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

1134435:AC731 RS00830
gene id: 1134435:AC731_RS00830
uniprot id: A0A140ICZ7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

1134435:AC731 RS00765
gene id: 1134435:AC731_RS00765
uniprot id: A0A140ICY4
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

1134435:AC731 RS16880
gene id: 1134435:AC731_RS16880
uniprot id: A0A127K920
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1134435:AC731 RS19355
gene id: 1134435:AC731_RS19355
uniprot id: A0A127KAA6
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS03255
gene id: 1134435:AC731_RS03255
uniprot id: A0A140IE66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

1134435:AC731 RS18765
gene id: 1134435:AC731_RS18765
uniprot id: A0A127KA28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

1134435:AC731 RS04015
gene id: 1134435:AC731_RS04015
uniprot id: A0A140IEK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1134435:AC731 RS02010
gene id: 1134435:AC731_RS02010
uniprot id: A0A140IDK2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

1134435:AC731 RS09265
gene id: 1134435:AC731_RS09265
uniprot id: A0A127K589
names: Similarity
messages: Belongs to the peptidase M1 family.

1134435:AC731 RS05705
gene id: 1134435:AC731_RS05705
uniprot id: A0A127K3D5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Exported by the Tat system.
messages: Periplasm
messages: Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions.

1134435:AC731 RS03705
gene id: 1134435:AC731_RS03705
uniprot id: A0A140IEE6
names: Similarity
messages: Belongs to the MoaD family.

1134435:AC731 RS18050
gene id: 1134435:AC731_RS18050
uniprot id: A0A127K9N8
names: Similarity
messages: Belongs to the BolA/IbaG family.

1134435:AC731 RS15060
gene id: 1134435:AC731_RS15060
uniprot id: A0A127K863
names: Function
names: Similarity
messages: Belongs to the DadA oxidoreductase family.
messages: Oxidative deamination of D-amino acids.

1134435:AC731 RS05860
gene id: 1134435:AC731_RS05860
uniprot id: A0A127K3G2
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS05075
gene id: 1134435:AC731_RS05075
uniprot id: A0A127K329
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS05105
gene id: 1134435:AC731_RS05105
uniprot id: A0A127K433
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

1134435:AC731 RS13575
gene id: 1134435:AC731_RS13575
uniprot id: A0A127K7D4
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

1134435:AC731 RS04500
gene id: 1134435:AC731_RS04500
uniprot id: A0A127K2S4
names: Similarity
messages: Belongs to the MEMO1 family.

1134435:AC731 RS17840
gene id: 1134435:AC731_RS17840
uniprot id: A0A127KAE6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1134435:AC731 RS17960
gene id: 1134435:AC731_RS17960
uniprot id: A0A127KAG6
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

1134435:AC731 RS03850
gene id: 1134435:AC731_RS03850
uniprot id: A0A140IEH1
names: Similarity
messages: Belongs to the histone deacetylase family.

1134435:AC731 RS14835
gene id: 1134435:AC731_RS14835
uniprot id: A0A127K878
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

1134435:AC731 RS03875
gene id: 1134435:AC731_RS03875
uniprot id: A0A140IEH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

1134435:AC731 RS17505
gene id: 1134435:AC731_RS17505
uniprot id: A0A127K9I3
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

1134435:AC731 RS13650
gene id: 1134435:AC731_RS13650
uniprot id: A0A127K7E7
names: Similarity
messages: Belongs to the DEAD box helicase family.

1134435:AC731 RS12560
gene id: 1134435:AC731_RS12560
uniprot id: A0A127K6V8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

1134435:AC731 RS01640
gene id: 1134435:AC731_RS01640
uniprot id: A0A140IDD5
names: Similarity
messages: Belongs to the peptidase A31 family.

1134435:AC731 RS09550
gene id: 1134435:AC731_RS09550
uniprot id: A0A127K5E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1134435:AC731 RS04660
gene id: 1134435:AC731_RS04660
uniprot id: A0A127K2U9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS18800
gene id: 1134435:AC731_RS18800
uniprot id: A0A127KA12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1134435:AC731 RS10095
gene id: 1134435:AC731_RS10095
uniprot id: A0A127K6K9
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

1134435:AC731 RS18925
gene id: 1134435:AC731_RS18925
uniprot id: A0A127KAY9
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

1134435:AC731 RS04505
gene id: 1134435:AC731_RS04505
uniprot id: A0A127K2S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

1134435:AC731 RS10570
gene id: 1134435:AC731_RS10570
uniprot id: A0A127K5X7
names: Similarity
messages: Belongs to the acylphosphatase family.

1134435:AC731 RS12970
gene id: 1134435:AC731_RS12970
uniprot id: A0A127K752
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

1134435:AC731 RS04185
gene id: 1134435:AC731_RS04185
uniprot id: A0A140IEM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

1134435:AC731 RS10615
gene id: 1134435:AC731_RS10615
uniprot id: A0A127KAT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

1134435:AC731 RS13640
gene id: 1134435:AC731_RS13640
uniprot id: A0A127K880
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1134435:AC731 RS02640
gene id: 1134435:AC731_RS02640
uniprot id: A0A140IDW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

1134435:AC731 RS07835
gene id: 1134435:AC731_RS07835
uniprot id: A0A127K4H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

1134435:AC731 RS09320
gene id: 1134435:AC731_RS09320
uniprot id: A0A127K5A4
names: Similarity
messages: Belongs to the WrbA family.

1134435:AC731 RS14170
gene id: 1134435:AC731_RS14170
uniprot id: A0A127K7P3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1134435:AC731 RS08660
gene id: 1134435:AC731_RS08660
uniprot id: A0A127K4Y8
names: Function
names: Similarity
messages: Belongs to the CofC family.
messages: Guanylyltransferase that catalyzes the activation of (2R)-3-phosphoglycerate (3PG) as 3-[(R)-glyceryl]-diphospho-5'-guanosine, via the condensation of 3PG with GTP. It is involved in the biosynthesis of a derivative of the hydride carrier cofactor coenzyme F420, 3PG-F420.

1134435:AC731 RS16055
gene id: 1134435:AC731_RS16055
uniprot id: A0A127K9G6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

1134435:AC731 RS17890
gene id: 1134435:AC731_RS17890
uniprot id: A0A127K9Q1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

1134435:AC731 RS09735
gene id: 1134435:AC731_RS09735
uniprot id: A0A127K5H7
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

1134435:AC731 RS05515
gene id: 1134435:AC731_RS05515
uniprot id: A0A127K3A7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

1134435:AC731 RS14195
gene id: 1134435:AC731_RS14195
uniprot id: A0A127K8H1
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS18135
gene id: 1134435:AC731_RS18135
uniprot id: A0A127K9R3
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

1134435:AC731 RS18185
gene id: 1134435:AC731_RS18185
uniprot id: A0A127K9R0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

1134435:AC731 RS19335
gene id: 1134435:AC731_RS19335
uniprot id: A0A127KB57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

1134435:AC731 RS03330
gene id: 1134435:AC731_RS03330
uniprot id: A0A140IE78
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1134435:AC731 RS14905
gene id: 1134435:AC731_RS14905
uniprot id: A0A127K8V8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

1134435:AC731 RS05100
gene id: 1134435:AC731_RS05100
uniprot id: A0A127K328
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

1134435:AC731 RS13420
gene id: 1134435:AC731_RS13420
uniprot id: A0A127K7H4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

1134435:AC731 RS14130
gene id: 1134435:AC731_RS14130
uniprot id: A0A127K7R0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

1134435:AC731 RS00840
gene id: 1134435:AC731_RS00840
uniprot id: A0A127KAD2
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

1134435:AC731 RS18075
gene id: 1134435:AC731_RS18075
uniprot id: A0A127KAI6
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1134435:AC731 RS01845
gene id: 1134435:AC731_RS01845
uniprot id: A0A140IDH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.
messages: Homotetramer.

1134435:AC731 RS10645
gene id: 1134435:AC731_RS10645
uniprot id: A0A127K5Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

1134435:AC731 RS10055
gene id: 1134435:AC731_RS10055
uniprot id: A0A127K5M8
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO small chain family.
messages: Heterohexadecamer of 8 large and 8 small subunits.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site. Although the small subunit is not catalytic it is essential for maximal activity.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.

1134435:AC731 RS02675
gene id: 1134435:AC731_RS02675
uniprot id: A0A140IDW5
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

1134435:AC731 RS06240
gene id: 1134435:AC731_RS06240
uniprot id: A0A127K3N3
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

1134435:AC731 RS02045
gene id: 1134435:AC731_RS02045
uniprot id: A0A140IDK9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

1134435:AC731 RS18100
gene id: 1134435:AC731_RS18100
uniprot id: A0A127K9Q6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

1134435:AC731 RS13685
gene id: 1134435:AC731_RS13685
uniprot id: A0A127K7E8
names: Similarity
messages: Belongs to the leucine-binding protein family.

1134435:AC731 RS10910
gene id: 1134435:AC731_RS10910
uniprot id: A0A127K614
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

1134435:AC731 RS03980
gene id: 1134435:AC731_RS03980
uniprot id: A0A140IEJ5
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

1134435:AC731 RS11950
gene id: 1134435:AC731_RS11950
uniprot id: A0A127K6K6
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS01290
gene id: 1134435:AC731_RS01290
uniprot id: A0A140ID75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

1134435:AC731 RS09765
gene id: 1134435:AC731_RS09765
uniprot id: A0A127K5I5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

1134435:AC731 RS16940
gene id: 1134435:AC731_RS16940
uniprot id: A0A127K921
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1134435:AC731 RS13995
gene id: 1134435:AC731_RS13995
uniprot id: A0A127K7K5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

1134435:AC731 RS14890
gene id: 1134435:AC731_RS14890
uniprot id: A0A127K884
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S49 family.
messages: Cell inner membrane

1134435:AC731 RS03325
gene id: 1134435:AC731_RS03325
uniprot id: A0A127KAK9
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

1134435:AC731 RS14870
gene id: 1134435:AC731_RS14870
uniprot id: A0A127K838
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

1134435:AC731 RS06850
gene id: 1134435:AC731_RS06850
uniprot id: A0A127K4X6
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

1134435:AC731 RS08335
gene id: 1134435:AC731_RS08335
uniprot id: A0A127K4S1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1134435:AC731 RS07230
gene id: 1134435:AC731_RS07230
uniprot id: A0A127K476
names: Similarity
messages: Belongs to the creatininase superfamily.

1134435:AC731 RS16100
gene id: 1134435:AC731_RS16100
uniprot id: A0A127K8V4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

1134435:AC731 RS11850
gene id: 1134435:AC731_RS11850
uniprot id: A0A127K6J2
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.

1134435:AC731 RS13635
gene id: 1134435:AC731_RS13635
uniprot id: A0A127KAZ6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1134435:AC731 RS01720
gene id: 1134435:AC731_RS01720
uniprot id: A0A140IDE9
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1134435:AC731 RS03160
gene id: 1134435:AC731_RS03160
uniprot id: A0A140IE48
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1134435:AC731 RS16520
gene id: 1134435:AC731_RS16520
uniprot id: A0A127K8X4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

1134435:AC731 RS18155
gene id: 1134435:AC731_RS18155
uniprot id: A0A127K9Q8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

1134435:AC731 RS02110
gene id: 1134435:AC731_RS02110
uniprot id: A0A140IDM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

1134435:AC731 RS14840
gene id: 1134435:AC731_RS14840
uniprot id: A0A127K849
names: Subcellular Location Annotation
messages: Nucleus

1134435:AC731 RS17810
gene id: 1134435:AC731_RS17810
uniprot id: A0A127K9K9
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS14310
gene id: 1134435:AC731_RS14310
uniprot id: A0A127K7R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

1134435:AC731 RS13160
gene id: 1134435:AC731_RS13160
uniprot id: A0A127K7B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

1134435:AC731 RS09855
gene id: 1134435:AC731_RS09855
uniprot id: A0A127K5J5
names: Similarity
messages: Belongs to the peptidase S41A family.

1134435:AC731 RS16630
gene id: 1134435:AC731_RS16630
uniprot id: A0A127K8Z3
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

1134435:AC731 RS12485
gene id: 1134435:AC731_RS12485
uniprot id: A0A127K6V2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

1134435:AC731 RS05680
gene id: 1134435:AC731_RS05680
uniprot id: A0A127K3D7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

1134435:AC731 RS14480
gene id: 1134435:AC731_RS14480
uniprot id: A0A127K7V9
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

1134435:AC731 RS09250
gene id: 1134435:AC731_RS09250
uniprot id: A0A127K592
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

1134435:AC731 RS09880
gene id: 1134435:AC731_RS09880
uniprot id: A0A127K6G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

1134435:AC731 RS18865
gene id: 1134435:AC731_RS18865
uniprot id: A0A127KA25
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

1134435:AC731 RS13630
gene id: 1134435:AC731_RS13630
uniprot id: A0A127K7D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

1134435:AC731 RS18325
gene id: 1134435:AC731_RS18325
uniprot id: A0A127K9U7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

1134435:AC731 RS07950
gene id: 1134435:AC731_RS07950
uniprot id: A0A127K4J2
names: Similarity
messages: Belongs to the PheA/TfdB FAD monooxygenase family.

1134435:AC731 RS17540
gene id: 1134435:AC731_RS17540
uniprot id: A0A127K9F9
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

1134435:AC731 RS06180
gene id: 1134435:AC731_RS06180
uniprot id: A0A127K3M2
names: Similarity
messages: Belongs to the UPF0751 family.

1134435:AC731 RS00930
gene id: 1134435:AC731_RS00930
uniprot id: A0A140ID12
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

1134435:AC731 RS11120
gene id: 1134435:AC731_RS11120
uniprot id: A0A127K713
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

1134435:AC731 RS04440
gene id: 1134435:AC731_RS04440
uniprot id: A0A127K2R9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

1134435:AC731 RS08585
gene id: 1134435:AC731_RS08585
uniprot id: A0A127K4Y0
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS07675
gene id: 1134435:AC731_RS07675
uniprot id: A0A127K5B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

1134435:AC731 RS04395
gene id: 1134435:AC731_RS04395
uniprot id: A0A127K2Q3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

1134435:AC731 RS12180
gene id: 1134435:AC731_RS12180
uniprot id: A0A127K6P5
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS16855
gene id: 1134435:AC731_RS16855
uniprot id: A0A127K996
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1134435:AC731 RS00030
gene id: 1134435:AC731_RS00030
uniprot id: A0A127KAJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

1134435:AC731 RS17060
gene id: 1134435:AC731_RS17060
uniprot id: A0A127K9D3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

1134435:AC731 RS08595
gene id: 1134435:AC731_RS08595
uniprot id: A0A127K4W0
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

1134435:AC731 RS19325
gene id: 1134435:AC731_RS19325
uniprot id: A0A127KAE4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

1134435:AC731 RS19220
gene id: 1134435:AC731_RS19220
uniprot id: A0A127KB34
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

1134435:AC731 RS10200
gene id: 1134435:AC731_RS10200
uniprot id: A0A127K5R1
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

1134435:AC731 RS12795
gene id: 1134435:AC731_RS12795
uniprot id: A0A127K719
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

1134435:AC731 RS06720
gene id: 1134435:AC731_RS06720
uniprot id: A0A127K3X1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

1134435:AC731 RS07925
gene id: 1134435:AC731_RS07925
uniprot id: A0A127K5E3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1134435:AC731 RS17880
gene id: 1134435:AC731_RS17880
uniprot id: A0A127K9T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

1134435:AC731 RS14520
gene id: 1134435:AC731_RS14520
uniprot id: A0A127K8N4
names: PTM
messages: Binds 1 heme group per subunit.

1134435:AC731 RS10195
gene id: 1134435:AC731_RS10195
uniprot id: A0A127K5R6
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

1134435:AC731 RS05755
gene id: 1134435:AC731_RS05755
uniprot id: A0A127K3E5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS00265
gene id: 1134435:AC731_RS00265
uniprot id: A0A140ICQ0
names: Similarity
messages: Belongs to the universal stress protein A family.

1134435:AC731 RS15950
gene id: 1134435:AC731_RS15950
uniprot id: A0A127K8K4
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

1134435:AC731 RS06800
gene id: 1134435:AC731_RS06800
uniprot id: A0A127K3Z9
names: Similarity
messages: Belongs to the fabD family.

1134435:AC731 RS16655
gene id: 1134435:AC731_RS16655
uniprot id: A0A127K928
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

1134435:AC731 RS17630
gene id: 1134435:AC731_RS17630
uniprot id: A0A127K9H1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

1134435:AC731 RS00525
gene id: 1134435:AC731_RS00525
uniprot id: A0A140ICU4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

1134435:AC731 RS19345
gene id: 1134435:AC731_RS19345
uniprot id: A0A127KAD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

1134435:AC731 RS01330
gene id: 1134435:AC731_RS01330
uniprot id: A0A140ID82
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

1134435:AC731 RS04820
gene id: 1134435:AC731_RS04820
uniprot id: A0A127K2Y2
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

1134435:AC731 RS03225
gene id: 1134435:AC731_RS03225
uniprot id: A0A140IE60
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

1134435:AC731 RS09705
gene id: 1134435:AC731_RS09705
uniprot id: A0A127K5H8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1134435:AC731 RS04265
gene id: 1134435:AC731_RS04265
uniprot id: A0A140IEP2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

1134435:AC731 RS15725
gene id: 1134435:AC731_RS15725
uniprot id: A0A127K8G4
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

1134435:AC731 RS03640
gene id: 1134435:AC731_RS03640
uniprot id: A0A140IED4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1134435:AC731 RS08630
gene id: 1134435:AC731_RS08630
uniprot id: A0A127K4X3
names: Similarity
messages: Belongs to the ArsC family.

1134435:AC731 RS04065
gene id: 1134435:AC731_RS04065
uniprot id: A0A127KAK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

1134435:AC731 RS15780
gene id: 1134435:AC731_RS15780
uniprot id: A0A127K8H7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1134435:AC731 RS10080
gene id: 1134435:AC731_RS10080
uniprot id: A0A127K5N7
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1134435:AC731 RS17065
gene id: 1134435:AC731_RS17065
uniprot id: A0A127K9A7
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

1134435:AC731 RS10535
gene id: 1134435:AC731_RS10535
uniprot id: A0A127K5X0
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

1134435:AC731 RS09025
gene id: 1134435:AC731_RS09025
uniprot id: A0A127K548
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

1134435:AC731 RS04385
gene id: 1134435:AC731_RS04385
uniprot id: A0A127K2Q9
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

1134435:AC731 RS13975
gene id: 1134435:AC731_RS13975
uniprot id: A0A127K7S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

1134435:AC731 RS03265
gene id: 1134435:AC731_RS03265
uniprot id: A0A140IE68
names: Similarity
messages: Belongs to the ABC transporter superfamily.

1134435:AC731 RS15865
gene id: 1134435:AC731_RS15865
uniprot id: A0A127K8R5
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

1134435:AC731 RS11540
gene id: 1134435:AC731_RS11540
uniprot id: A0A127K6G6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

1134435:AC731 RS18775
gene id: 1134435:AC731_RS18775
uniprot id: A0A127KA24
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

1134435:AC731 RS18365
gene id: 1134435:AC731_RS18365
uniprot id: A0A127K9T6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

1134435:AC731 RS17815
gene id: 1134435:AC731_RS17815
uniprot id: A0A127K9J7
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS01190
gene id: 1134435:AC731_RS01190
uniprot id: A0A140ID57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

1134435:AC731 RS18645
gene id: 1134435:AC731_RS18645
uniprot id: A0A127KA05
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

1134435:AC731 RS00680
gene id: 1134435:AC731_RS00680
uniprot id: A0A140ICW8
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

1134435:AC731 RS09830
gene id: 1134435:AC731_RS09830
uniprot id: A0A127K5K3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS10030
gene id: 1134435:AC731_RS10030
uniprot id: A0A127K5M7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

1134435:AC731 RS04460
gene id: 1134435:AC731_RS04460
uniprot id: A0A127K2R7
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

1134435:AC731 RS18465
gene id: 1134435:AC731_RS18465
uniprot id: A0A127K9W0
names: Similarity
messages: Belongs to the UPF0102 family.

1134435:AC731 RS18090
gene id: 1134435:AC731_RS18090
uniprot id: A0A127K9Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

1134435:AC731 RS12995
gene id: 1134435:AC731_RS12995
uniprot id: A0A127K781
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

1134435:AC731 RS15975
gene id: 1134435:AC731_RS15975
uniprot id: A0A127K8K2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1134435:AC731 RS16250
gene id: 1134435:AC731_RS16250
uniprot id: A0A127K8S9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1134435:AC731 RS08155
gene id: 1134435:AC731_RS08155
uniprot id: A0A127K4N4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.

1134435:AC731 RS09825
gene id: 1134435:AC731_RS09825
uniprot id: A0A127K6F2
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

1134435:AC731 RS19165
gene id: 1134435:AC731_RS19165
uniprot id: A0A127KBC7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1134435:AC731 RS10070
gene id: 1134435:AC731_RS10070
uniprot id: A0A127K5R4
names: Similarity
messages: Belongs to the phosphoribulokinase family.

1134435:AC731 RS12240
gene id: 1134435:AC731_RS12240
uniprot id: A0A127K7K1
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

1134435:AC731 RS09995
gene id: 1134435:AC731_RS09995
uniprot id: A0A127K6I8
names: Similarity
messages: Belongs to the phosphoribulokinase family.

1134435:AC731 RS10010
gene id: 1134435:AC731_RS10010
uniprot id: A0A127K5M9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

1134435:AC731 RS04990
gene id: 1134435:AC731_RS04990
uniprot id: A0A127K303
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1134435:AC731 RS04455
gene id: 1134435:AC731_RS04455
uniprot id: A0A127K2R3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

1134435:AC731 RS17430
gene id: 1134435:AC731_RS17430
uniprot id: A0A127K9B2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1134435:AC731 RS08905
gene id: 1134435:AC731_RS08905
uniprot id: A0A127K528
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

1134435:AC731 RS11890
gene id: 1134435:AC731_RS11890
uniprot id: A0A127K6M8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1134435:AC731 RS01140
gene id: 1134435:AC731_RS01140
uniprot id: A0A140ID48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

1134435:AC731 RS09395
gene id: 1134435:AC731_RS09395
uniprot id: A0A127K5B9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

1134435:AC731 RS11555
gene id: 1134435:AC731_RS11555
uniprot id: A0A127K6D4
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

1134435:AC731 RS02420
gene id: 1134435:AC731_RS02420
uniprot id: A0A140IDS4
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS15435
gene id: 1134435:AC731_RS15435
uniprot id: A0A127K8C0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1134435:AC731 RS18840
gene id: 1134435:AC731_RS18840
uniprot id: A0A127KA29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1134435:AC731 RS02650
gene id: 1134435:AC731_RS02650
uniprot id: A0A140IDW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

1134435:AC731 RS17575
gene id: 1134435:AC731_RS17575
uniprot id: A0A127K9F0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

1134435:AC731 RS09965
gene id: 1134435:AC731_RS09965
uniprot id: A0A127K5L3
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

1134435:AC731 RS01520
gene id: 1134435:AC731_RS01520
uniprot id: A0A140IDB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

1134435:AC731 RS06255
gene id: 1134435:AC731_RS06255
uniprot id: A0A127K3P4
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS02180
gene id: 1134435:AC731_RS02180
uniprot id: A0A140IDN4
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS14940
gene id: 1134435:AC731_RS14940
uniprot id: A0A127K895
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

1134435:AC731 RS10150
gene id: 1134435:AC731_RS10150
uniprot id: A0A127K5Q9
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

1134435:AC731 RS19200
gene id: 1134435:AC731_RS19200
uniprot id: A0A127KAF8
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

1134435:AC731 RS10605
gene id: 1134435:AC731_RS10605
uniprot id: A0A127K5W4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

1134435:AC731 RS06175
gene id: 1134435:AC731_RS06175
uniprot id: A0A127K3L4
names: Similarity
messages: Belongs to the peptidase C40 family.

1134435:AC731 RS07790
gene id: 1134435:AC731_RS07790
uniprot id: A0A127KAN8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

1134435:AC731 RS00320
gene id: 1134435:AC731_RS00320
uniprot id: A0A140ICR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

1134435:AC731 RS09670
gene id: 1134435:AC731_RS09670
uniprot id: A0A127K5G7
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

1134435:AC731 RS18560
gene id: 1134435:AC731_RS18560
uniprot id: A0A127KA17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

1134435:AC731 RS18175
gene id: 1134435:AC731_RS18175
uniprot id: A0A127K9R5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

1134435:AC731 RS05845
gene id: 1134435:AC731_RS05845
uniprot id: A0A127K3G1
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS16715
gene id: 1134435:AC731_RS16715
uniprot id: A0A127K9T7
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

1134435:AC731 RS03305
gene id: 1134435:AC731_RS03305
uniprot id: A0A140IE74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

1134435:AC731 RS03840
gene id: 1134435:AC731_RS03840
uniprot id: A0A140IEG9
names: Similarity
messages: Belongs to the YjdM family.

1134435:AC731 RS09130
gene id: 1134435:AC731_RS09130
uniprot id: A0A127K572
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

1134435:AC731 RS00055
gene id: 1134435:AC731_RS00055
uniprot id: A0A140ICL1
names: Subcellular Location Annotation
messages: Cytoplasm

1134435:AC731 RS19255
gene id: 1134435:AC731_RS19255
uniprot id: A0A127KAA4
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

1134435:AC731 RS06815
gene id: 1134435:AC731_RS06815
uniprot id: A0A127K3Z8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

1134435:AC731 RS09805
gene id: 1134435:AC731_RS09805
uniprot id: A0A127K5I7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1134435:AC731 RS10375
gene id: 1134435:AC731_RS10375
uniprot id: A0A127K5U2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1134435:AC731 RS06070
gene id: 1134435:AC731_RS06070
uniprot id: A0A127K3K0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

1134435:AC731 RS00925
gene id: 1134435:AC731_RS00925
uniprot id: A0A140ID11
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

1134435:AC731 RS09230
gene id: 1134435:AC731_RS09230
uniprot id: A0A127K583
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

1134435:AC731 RS17195
gene id: 1134435:AC731_RS17195
uniprot id: A0A127K9A1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

1134435:AC731 RS02270
gene id: 1134435:AC731_RS02270
uniprot id: A0A140IDP8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

1134435:AC731 RS00845
gene id: 1134435:AC731_RS00845
uniprot id: A0A140ICZ9
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

1134435:AC731 RS10700
gene id: 1134435:AC731_RS10700
uniprot id: A0A127K5Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

1134435:AC731 RS14965
gene id: 1134435:AC731_RS14965
uniprot id: A0A127K835
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1134435:AC731 RS11520
gene id: 1134435:AC731_RS11520
uniprot id: A0A127K6C7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

1134435:AC731 RS15030
gene id: 1134435:AC731_RS15030
uniprot id: A0A127K843
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

1134435:AC731 RS06930
gene id: 1134435:AC731_RS06930
uniprot id: A0A127K418
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

1134435:AC731 RS00470
gene id: 1134435:AC731_RS00470
uniprot id: A0A140ICT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

1134435:AC731 RS16505
gene id: 1134435:AC731_RS16505
uniprot id: A0A127K8V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

1134435:AC731 RS11595
gene id: 1134435:AC731_RS11595
uniprot id: A0A127K6I0
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

1134435:AC731 RS09645
gene id: 1134435:AC731_RS09645
uniprot id: A0A127KAS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

1134435:AC731 RS14440
gene id: 1134435:AC731_RS14440
uniprot id: A0A127K7T1
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 104 family.
messages: Protein-arginine rhamnosyltransferase that catalyzes the transfer of a single rhamnose to elongation factor P (EF-P) on 'Lys-32', a modification required for EF-P-dependent rescue of polyproline stalled ribosomes.

1134435:AC731 RS09655
gene id: 1134435:AC731_RS09655
uniprot id: A0A127K5G3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

1134435:AC731 RS03165
gene id: 1134435:AC731_RS03165
uniprot id: A0A140IE49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

1134435:AC731 RS12015
gene id: 1134435:AC731_RS12015
uniprot id: A0A127K6L5
names: Similarity
messages: Belongs to the UPF0502 family.

1134435:AC731 RS02065
gene id: 1134435:AC731_RS02065
uniprot id: A0A140IDL2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

1134435:AC731 RS13240
gene id: 1134435:AC731_RS13240
uniprot id: A0A127K7A0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

1134435:AC731 RS17835
gene id: 1134435:AC731_RS17835
uniprot id: A0A127K9K4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1134435:AC731 RS11245
gene id: 1134435:AC731_RS11245
uniprot id: A0A127K729
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS17500
gene id: 1134435:AC731_RS17500
uniprot id: A0A127K9L3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

1134435:AC731 RS11015
gene id: 1134435:AC731_RS11015
uniprot id: A0A127K631
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS00215
gene id: 1134435:AC731_RS00215
uniprot id: A0A140ICP0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1134435:AC731 RS09335
gene id: 1134435:AC731_RS09335
uniprot id: A0A127K5A6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

1134435:AC731 RS16680
gene id: 1134435:AC731_RS16680
uniprot id: A0A127K906
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1134435:AC731 RS11060
gene id: 1134435:AC731_RS11060
uniprot id: A0A127K650
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS02905
gene id: 1134435:AC731_RS02905
uniprot id: A0A127KAG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

1134435:AC731 RS13945
gene id: 1134435:AC731_RS13945
uniprot id: A0A127K7I2
names: Similarity
messages: Belongs to the UPF0250 family.

1134435:AC731 RS00085
gene id: 1134435:AC731_RS00085
uniprot id: A0A140ICL6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

1134435:AC731 RS00045
gene id: 1134435:AC731_RS00045
uniprot id: A0A140ICL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

1134435:AC731 RS02130
gene id: 1134435:AC731_RS02130
uniprot id: A0A140IDM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

1134435:AC731 RS15895
gene id: 1134435:AC731_RS15895
uniprot id: A0A127K8J4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

1134435:AC731 RS17095
gene id: 1134435:AC731_RS17095
uniprot id: A0A127K952
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1134435:AC731 RS05145
gene id: 1134435:AC731_RS05145
uniprot id: A0A127K337
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.

1134435:AC731 RS03285
gene id: 1134435:AC731_RS03285
uniprot id: A0A140IE71
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

1134435:AC731 RS08745
gene id: 1134435:AC731_RS08745
uniprot id: A0A127K4Y6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

1134435:AC731 RS17760
gene id: 1134435:AC731_RS17760
uniprot id: A0A127K9I7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

1134435:AC731 RS09820
gene id: 1134435:AC731_RS09820
uniprot id: A0A127K5J4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

1134435:AC731 RS00605
gene id: 1134435:AC731_RS00605
uniprot id: A0A140ICW0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

1134435:AC731 RS16670
gene id: 1134435:AC731_RS16670
uniprot id: A0A127K8Y6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiV subfamily.
messages: Forms an heterodimer with UbiU.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiU, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

1134435:AC731 RS06855
gene id: 1134435:AC731_RS06855
uniprot id: A0A127K410
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

1134435:AC731 RS08085
gene id: 1134435:AC731_RS08085
uniprot id: A0A127K4L2
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS05060
gene id: 1134435:AC731_RS05060
uniprot id: A0A127K325
names: Similarity
messages: Belongs to the skp family.

1134435:AC731 RS17450
gene id: 1134435:AC731_RS17450
uniprot id: A0A127K9H4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

1134435:AC731 RS10265
gene id: 1134435:AC731_RS10265
uniprot id: A0A127K5T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

1134435:AC731 RS11690
gene id: 1134435:AC731_RS11690
uniprot id: A0A127K7A8
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.

1134435:AC731 RS18065
gene id: 1134435:AC731_RS18065
uniprot id: A0A127K9T1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

1134435:AC731 RS12980
gene id: 1134435:AC731_RS12980
uniprot id: A0A127K749
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

1134435:AC731 RS14745
gene id: 1134435:AC731_RS14745
uniprot id: A0A127K7Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

1134435:AC731 RS18530
gene id: 1134435:AC731_RS18530
uniprot id: A0A127K9Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

1134435:AC731 RS16415
gene id: 1134435:AC731_RS16415
uniprot id: A0A127K8T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

1134435:AC731 RS12275
gene id: 1134435:AC731_RS12275
uniprot id: A0A127K6W5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

1134435:AC731 RS16300
gene id: 1134435:AC731_RS16300
uniprot id: A0A127K8T9
names: Function
names: Similarity
messages: Also exhibits in vitro acyl transferase activity, transferring the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates.
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family.
messages: Catalyzes the hydrolysis of short-chain aliphatic amides to their corresponding organic acids with release of ammonia.

1134435:AC731 RS07625
gene id: 1134435:AC731_RS07625
uniprot id: A0A127K4E8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1134435:AC731 RS13990
gene id: 1134435:AC731_RS13990
uniprot id: A0A127K8D6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

1134435:AC731 RS18520
gene id: 1134435:AC731_RS18520
uniprot id: A0A127KAS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

1134435:AC731 RS01365
gene id: 1134435:AC731_RS01365
uniprot id: A0A140ID89
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

1134435:AC731 RS14780
gene id: 1134435:AC731_RS14780
uniprot id: A0A127K867
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS08050
gene id: 1134435:AC731_RS08050
uniprot id: A0A127K4L3
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1134435:AC731 RS16375
gene id: 1134435:AC731_RS16375
uniprot id: A0A127K8S2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

1134435:AC731 RS06350
gene id: 1134435:AC731_RS06350
uniprot id: A0A127K4Q1
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.

1134435:AC731 RS04710
gene id: 1134435:AC731_RS04710
uniprot id: A0A127K2W6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PqqD family.
messages: Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.
messages: Monomer. Interacts with PqqE.

1134435:AC731 RS00230
gene id: 1134435:AC731_RS00230
uniprot id: A0A140ICP3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

1134435:AC731 RS17205
gene id: 1134435:AC731_RS17205
uniprot id: A0A127K9A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

1134435:AC731 RS08025
gene id: 1134435:AC731_RS08025
uniprot id: A0A127K4K6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1134435:AC731 RS06770
gene id: 1134435:AC731_RS06770
uniprot id: A0A127K3Y1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

1134435:AC731 RS04595
gene id: 1134435:AC731_RS04595
uniprot id: A0A127K2U0
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

1134435:AC731 RS13655
gene id: 1134435:AC731_RS13655
uniprot id: A0A127K7H1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

1134435:AC731 RS13275
gene id: 1134435:AC731_RS13275
uniprot id: A0A127K825
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

1134435:AC731 RS17350
gene id: 1134435:AC731_RS17350
uniprot id: A0A127KB43
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

1134435:AC731 RS09140
gene id: 1134435:AC731_RS09140
uniprot id: A0A127K566
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS19150
gene id: 1134435:AC731_RS19150
uniprot id: A0A127KA75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
messages: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
messages: Cytoplasm
messages: Monomer.

1134435:AC731 RS01005
gene id: 1134435:AC731_RS01005
uniprot id: A0A140ID24
names: Similarity
messages: Belongs to the histone deacetylase family.

1134435:AC731 RS14005
gene id: 1134435:AC731_RS14005
uniprot id: A0A127K7M0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

1134435:AC731 RS01030
gene id: 1134435:AC731_RS01030
uniprot id: A0A140ID29
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

1134435:AC731 RS00595
gene id: 1134435:AC731_RS00595
uniprot id: A0A140ICV8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

1134435:AC731 RS04580
gene id: 1134435:AC731_RS04580
uniprot id: A0A127K2U6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1134435:AC731 RS05085
gene id: 1134435:AC731_RS05085
uniprot id: A0A127K323
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

1134435:AC731 RS01110
gene id: 1134435:AC731_RS01110
uniprot id: A0A140ID42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

1134435:AC731 RS11830
gene id: 1134435:AC731_RS11830
uniprot id: A0A127K6M1
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS08560
gene id: 1134435:AC731_RS08560
uniprot id: A0A127K4X4
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.

1134435:AC731 RS01405
gene id: 1134435:AC731_RS01405
uniprot id: A0A140ID97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

1134435:AC731 RS00330
gene id: 1134435:AC731_RS00330
uniprot id: A0A127KAE5
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

1134435:AC731 RS08380
gene id: 1134435:AC731_RS08380
uniprot id: A0A127K4T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

1134435:AC731 RS13020
gene id: 1134435:AC731_RS13020
uniprot id: A0A127K734
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

1134435:AC731 RS06735
gene id: 1134435:AC731_RS06735
uniprot id: A0A127K3X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

1134435:AC731 RS09660
gene id: 1134435:AC731_RS09660
uniprot id: A0A127K5H1
names: Similarity
messages: Belongs to the cytochrome P450 family.

1134435:AC731 RS01635
gene id: 1134435:AC731_RS01635
uniprot id: A0A140IDD4
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

1134435:AC731 RS03320
gene id: 1134435:AC731_RS03320
uniprot id: A0A140IE77
names: Similarity
messages: Belongs to the citrate synthase family.

1134435:AC731 RS09360
gene id: 1134435:AC731_RS09360
uniprot id: A0A127K5C1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

1134435:AC731 RS01100
gene id: 1134435:AC731_RS01100
uniprot id: A0A140ID40
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

1134435:AC731 RS10315
gene id: 1134435:AC731_RS10315
uniprot id: A0A127K5T1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

1134435:AC731 RS09100
gene id: 1134435:AC731_RS09100
uniprot id: A0A127K568
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS07875
gene id: 1134435:AC731_RS07875
uniprot id: A0A127K4J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Cytoplasm

1134435:AC731 RS12770
gene id: 1134435:AC731_RS12770
uniprot id: A0A127K712
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

1134435:AC731 RS13225
gene id: 1134435:AC731_RS13225
uniprot id: A0A127K813
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

1134435:AC731 RS03275
gene id: 1134435:AC731_RS03275
uniprot id: A0A140IE69
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1134435:AC731 RS10875
gene id: 1134435:AC731_RS10875
uniprot id: A0A127K651
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

1134435:AC731 RS05080
gene id: 1134435:AC731_RS05080
uniprot id: A0A127K324
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

1134435:AC731 RS17945
gene id: 1134435:AC731_RS17945
uniprot id: A0A127K9U3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

1134435:AC731 RS04180
gene id: 1134435:AC731_RS04180
uniprot id: A0A140IEM8
names: Similarity
messages: Belongs to the disproportionating enzyme family.

1134435:AC731 RS07660
gene id: 1134435:AC731_RS07660
uniprot id: A0A127K4D5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

1134435:AC731 RS13425
gene id: 1134435:AC731_RS13425
uniprot id: A0A127K7D2
names: Similarity
messages: Belongs to the TlyA family.

1134435:AC731 RS19110
gene id: 1134435:AC731_RS19110
uniprot id: A0A127KA92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

1134435:AC731 RS14660
gene id: 1134435:AC731_RS14660
uniprot id: A0A127K847
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0187 family.
messages: Membrane

1134435:AC731 RS18180
gene id: 1134435:AC731_RS18180
uniprot id: A0A127KAK5
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

1134435:AC731 RS04225
gene id: 1134435:AC731_RS04225
uniprot id: A0A140IEN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

1134435:AC731 RS11005
gene id: 1134435:AC731_RS11005
uniprot id: A0A127KB04
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

1134435:AC731 RS00960
gene id: 1134435:AC731_RS00960
uniprot id: A0A140ID16
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

1134435:AC731 RS10655
gene id: 1134435:AC731_RS10655
uniprot id: A0A127K5Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

1134435:AC731 RS13590
gene id: 1134435:AC731_RS13590
uniprot id: A0A127K7D6
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

1134435:AC731 RS15225
gene id: 1134435:AC731_RS15225
uniprot id: A0A127K872
names: Similarity
messages: Belongs to the universal stress protein A family.

1134435:AC731 RS14010
gene id: 1134435:AC731_RS14010
uniprot id: A0A127K7K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

1134435:AC731 RS00715
gene id: 1134435:AC731_RS00715
uniprot id: A0A140ICX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

1134435:AC731 RS10820
gene id: 1134435:AC731_RS10820
uniprot id: A0A127K609
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

1134435:AC731 RS05055
gene id: 1134435:AC731_RS05055
uniprot id: A0A127K422
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

1134435:AC731 RS05590
gene id: 1134435:AC731_RS05590
uniprot id: A0A127K3B8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

1134435:AC731 RS13280
gene id: 1134435:AC731_RS13280
uniprot id: A0A127K784
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

1134435:AC731 RS03260
gene id: 1134435:AC731_RS03260
uniprot id: A0A140IE67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

1134435:AC731 RS04680
gene id: 1134435:AC731_RS04680
uniprot id: A0A127K2V6
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

1134435:AC731 RS18000
gene id: 1134435:AC731_RS18000
uniprot id: A0A127K9V8
names: Similarity
messages: Belongs to the GSP E family.

1134435:AC731 RS11020
gene id: 1134435:AC731_RS11020
uniprot id: A0A127K633
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

1134435:AC731 RS01245
gene id: 1134435:AC731_RS01245
uniprot id: A0A127KB81
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

1134435:AC731 RS03960
gene id: 1134435:AC731_RS03960
uniprot id: A0A140IEJ1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

1134435:AC731 RS03880
gene id: 1134435:AC731_RS03880
uniprot id: A0A140IEH7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

1134435:AC731 RS02840
gene id: 1134435:AC731_RS02840
uniprot id: A0A140IDZ4
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

1134435:AC731 RS08545
gene id: 1134435:AC731_RS08545
uniprot id: A0A127K5R3
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

1134435:AC731 RS14735
gene id: 1134435:AC731_RS14735
uniprot id: A0A127K8S3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

1134435:AC731 RS11985
gene id: 1134435:AC731_RS11985
uniprot id: A0A127K6J4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

1134435:AC731 RS00165
gene id: 1134435:AC731_RS00165
uniprot id: A0A140ICN2
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.

1134435:AC731 RS12205
gene id: 1134435:AC731_RS12205
uniprot id: A0A127K6P9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

1134435:AC731 RS04075
gene id: 1134435:AC731_RS04075
uniprot id: A0A140IEL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

1134435:AC731 RS00695
gene id: 1134435:AC731_RS00695
uniprot id: A0A140ICX1
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS09840
gene id: 1134435:AC731_RS09840
uniprot id: A0A127K5K2
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

1134435:AC731 RS07330
gene id: 1134435:AC731_RS07330
uniprot id: A0A127K556
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

1134435:AC731 RS10365
gene id: 1134435:AC731_RS10365
uniprot id: A0A127K5T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

1134435:AC731 RS15660
gene id: 1134435:AC731_RS15660
uniprot id: A0A127K8G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

1134435:AC731 RS11390
gene id: 1134435:AC731_RS11390
uniprot id: A0A127K6D6
names: Similarity
messages: Belongs to the pirin family.

1134435:AC731 RS07500
gene id: 1134435:AC731_RS07500
uniprot id: A0A127K4C3
names: Similarity
messages: Belongs to the peptidase C40 family.

1134435:AC731 RS05610
gene id: 1134435:AC731_RS05610
uniprot id: A0A127K3C5
names: Similarity
messages: Belongs to the transglycosylase Slt family.

1134435:AC731 RS05065
gene id: 1134435:AC731_RS05065
uniprot id: A0A127K318
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

1134435:AC731 RS02730
gene id: 1134435:AC731_RS02730
uniprot id: A0A140IDX5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SoxA family.
messages: Heterodimer of SoxA and SoxX.
messages: Periplasm

1134435:AC731 RS10575
gene id: 1134435:AC731_RS10575
uniprot id: A0A127K600
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

1134435:AC731 RS09815
gene id: 1134435:AC731_RS09815
uniprot id: A0A127K5J9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 7 family.
messages: Homodimer.
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: Periplasm

1134435:AC731 RS13290
gene id: 1134435:AC731_RS13290
uniprot id: A0A127K7A9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

1134435:AC731 RS00725
gene id: 1134435:AC731_RS00725
uniprot id: A0A127KB72
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

1134435:AC731 RS01960
gene id: 1134435:AC731_RS01960
uniprot id: A0A140IDJ2
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

1134435:AC731 RS16010
gene id: 1134435:AC731_RS16010
uniprot id: A0A127K8L2
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS01850
gene id: 1134435:AC731_RS01850
uniprot id: A0A140IDH4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

1134435:AC731 RS15015
gene id: 1134435:AC731_RS15015
uniprot id: A0A127K840
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

1134435:AC731 RS18070
gene id: 1134435:AC731_RS18070
uniprot id: A0A127K9P6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

1134435:AC731 RS18740
gene id: 1134435:AC731_RS18740
uniprot id: A0A127KA04
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family.

1134435:AC731 RS17580
gene id: 1134435:AC731_RS17580
uniprot id: A0A127K9G1
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

1134435:AC731 RS16675
gene id: 1134435:AC731_RS16675
uniprot id: A0A127K8Y1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiU subfamily.
messages: Forms an heterodimer with UbiV.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiV, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

1134435:AC731 RS16040
gene id: 1134435:AC731_RS16040
uniprot id: A0A127K8U4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

1134435:AC731 RS13450
gene id: 1134435:AC731_RS13450
uniprot id: A0A127K7B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

1134435:AC731 RS10690
gene id: 1134435:AC731_RS10690
uniprot id: A0A127K5Z6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

1134435:AC731 RS14620
gene id: 1134435:AC731_RS14620
uniprot id: A0A127K7Y5
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family.

1134435:AC731 RS01090
gene id: 1134435:AC731_RS01090
uniprot id: A0A140ID38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

1134435:AC731 RS10755
gene id: 1134435:AC731_RS10755
uniprot id: A0A127K632
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS09310
gene id: 1134435:AC731_RS09310
uniprot id: A0A127K5B2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

1134435:AC731 RS11275
gene id: 1134435:AC731_RS11275
uniprot id: A0A127K6B8
names: Similarity
messages: Belongs to the asparagine synthetase family.

1134435:AC731 RS18475
gene id: 1134435:AC731_RS18475
uniprot id: A0A127K9X4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

1134435:AC731 RS00060
gene id: 1134435:AC731_RS00060
uniprot id: A0A140ICL2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

1134435:AC731 RS18230
gene id: 1134435:AC731_RS18230
uniprot id: A0A127KAL3
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.

1134435:AC731 RS07620
gene id: 1134435:AC731_RS07620
uniprot id: A0A127K5A3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

1134435:AC731 RS07825
gene id: 1134435:AC731_RS07825
uniprot id: A0A127K4G9
names: Subcellular Location Annotation
messages: Membrane

1134435:AC731 RS18470
gene id: 1134435:AC731_RS18470
uniprot id: A0A127K9Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

1134435:AC731 RS00935
gene id: 1134435:AC731_RS00935
uniprot id: A0A140ID13
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

1134435:AC731 RS02230
gene id: 1134435:AC731_RS02230
uniprot id: A0A140IDP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: Membrane

1134435:AC731 RS14570
gene id: 1134435:AC731_RS14570
uniprot id: A0A127K7X6
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

1134435:AC731 RS12110
gene id: 1134435:AC731_RS12110
uniprot id: A0A127K6R1
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

1134435:AC731 RS07935
gene id: 1134435:AC731_RS07935
uniprot id: A0A127K4K7
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

1134435:AC731 RS16025
gene id: 1134435:AC731_RS16025
uniprot id: A0A127K8M1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

1134435:AC731 RS11750
gene id: 1134435:AC731_RS11750
uniprot id: A0A127K6G5
names: Subcellular Location Annotation
messages: Membrane